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Domain assignment for D2IE21_9PICO from UniProt viral sequences

Domain architecture


Domain assignment details

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Strong hits

Sequence:  D2IE21_9PICO
Domain Number 1 Region: 1714-2173
Classification Level Classification E-value
Superfamily DNA/RNA polymerases 1.48e-111
Family RNA-dependent RNA-polymerase 0.0000196
Further Details:      
 
Domain Number 2 Region: 23-280
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 1.04e-53
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.0046
Further Details:      
 
Domain Number 3 Region: 261-538
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 8.47e-52
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.0064
Further Details:      
 
Domain Number 4 Region: 559-758
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 3.4e-31
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.028
Further Details:      
 
Domain Number 5 Region: 1512-1698
Classification Level Classification E-value
Superfamily Trypsin-like serine proteases 3.08e-28
Family Viral cysteine protease of trypsin fold 0.026
Further Details:      
 
Domain Number 6 Region: 1148-1303
Classification Level Classification E-value
Superfamily P-loop containing nucleoside triphosphate hydrolases 0.00000000188
Family RecA protein-like (ATPase-domain) 0.079
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) D2IE21_9PICO
Sequence length 2177
Comment AC=D2IE21; DE=SubName: Full=Polyprotein; OS=Human parechovirus 3. OC=Viruses; ssRNA positive-strand viruses, no DNA stage; Picornavirales; OC=Picornaviridae; Parechovirus.
Sequence
MESIKDLVNVATGAMDTLSLSNVEAEANNIISGNEVGGEIITKVADDASNLLGPNSFATT
AQPENKDVVQATTTVNTTNLTQHPSAPTIPFTPDFRNVDNFHSMAYDITTGDKNPSKLIR
LDTASWQTSYSRQYKITTVELPKSFWDDTRKPAYGQAKYFAAVRCGFHFQVQVNVNQGTA
GSALVVYEPKPVIDSRQYLEFGSLTNLPHVLMNLAETTQADLCIPYVADTNYVKTDSSDL
GQLRVYVWTPLSVPTGASNEVDVTVMGSLLQLDFQNPRPYGEDVEIYDNGPNKVNASKFN
KRKFLTASTKYKWTRTKVDIAEGPGTMNMANVLSTTGAQSVALVGERAFYDPRTAGSKSR
FDDMIKIAQLFSVMSDNTTPSSSSGIDKYGYFDWAATVAPQNMVHRNVVTLDQFPNLNLF
MNTYSYFRGSLIIRLSIYASTFNRGRLRMGFFPNCTHDTQLELDNAIYTICDIGSDNSFE
LTIPYSFSTWMRKTHGHQLGLFQVEVLNRLTYNSSSPNKVHCIVQGRLGDDAKFFCPTGS
LVSFQNSWGSQMDLTDPLCIEDNMENCKQSISPNELGLTSAQDDGPLGNEKPNYFLNFRT
MNVDIFTVSHTKVDNIFGRAWYVTSHDFNNGDTWRQKLTFPKEGHGMLSQFFAYFTGEIN
IHILYMAEQGFLRVAHTYDTEDNRKTFLSSNGVITIPAGEQMTLSVPFYSNKPLRTVRHD
SALGFLMCRPMMHGTTRTTAEVYVSLRCPNFFFPVPAPKPTGSRATALYDESPYVPTDNR
KMQLAYLDRGFYKHYGIIVGENVYQLDSDDIFKTALTGKARFTKTKLTPDWVIEEECELD
YFRVKYLESSVNSEHIFSVDHNCETIAKDIFGTHTLNQHQAIGLVGTILLTAGLMSTIKT
PVNATTIKEFFNHAVEGDEQGLSLLVQKCTTFFSSAATEILDNDLVKFIVKILVRILCYM
VLYCHKPNILTTACLSTLLIMDVTSSSVLSPSCKALMQCLMDGDVKKLAEVVAESMSNTD
DEEIKEQICDTVKYTKSILSNQGPFKGFNEVSTAFRHIDWWIHTLLKIKDMVLSVFKPSM
ESKAIQWLERNKEHVCAILDYASDIIVESKDQTKMKSQEFYQRYTDCLSKFKPIMAICFR
SCHNSISNTVYRLFQELARIPSRISTQNDLIRVEPIGVWIQGEPGQGKSFLTHTLSRQLQ
KSCKLNGVYTNPTASEFMDGYDNQDIHLIDDLGQTRKEKDIEMLCNCISSVPFIVPMAHL
EEKGKFYTSKLVIATTNKSDFSSTVLQDSGALKRRFPYIMHIRAAKAYSKAGKLNVSQAM
STMATGECWEVSKNGRDWETLKLKDLVQKITEDYQERQKNYDCWKQQLENQTLDDLDDAV
SYIKHNFPDAIPYIDEYLNIEMSTLIEQMEAFIEPRPSVFKCFATRVANQTRKAAKEVVE
WFSSKIKSMLSFVERNKAWLTVASAVTSAISILLLVTKIFKKEDSKDERAYNPTLPMAKP
KGTFPVSQREFKNEAPYDGQLEHIISQMAYITGSTTGHLTHCAGYQHDEIILHGHSIKYL
EQEEDLTLHYKNKVFTIENPSVTQVTLGGKPMDLAILKCKLPFRFKKNSKYYTNKIGTES
MLIWMTEQGIITKEVRRVHHSGGIKTREGTESTKTISYTVKSCKGMCGGLLISKVEGNFK
ILGMHIAGNGEMGVAIPFNFLKNDMSDQGIVTEITPMQPMYINTKTQIHKSPVYGAVEVK
MGPAVLSKSDPRLEEPVECLIKKSAAKYRVNKFQVNNELWQGVKACVKSKFREIFGINGI
VDMKTAILGTSHVNSMDLSTSAGYNFVKSGYKKKDLICLEPFSVSPMLEKLVQDKFHALL
KGNQITTVFNTCLKDELRKLDKISAGKTRCIEACEVDYCIVYRMIMMEIYDKIYQTPCYY
SGLAVGINPYKDWHFMINALNDYNYEMDYSQYDGSLSSMLLWEAVEVLAYCHDSPDLVMQ
LHKPVIDSDHVVFNERWLIHGGMPSGSPCTTVLNSLCNLMMCIYTTNLISPGIDCLPIVY
GDDVILSLDREIDPEKLQGIMADSFGAEVTGSRKDEPPSLKPRLEVEFLKRKPGYFPEST
FIVGKLDTENMIQHLMWMKNFSTFKQQLQSYLMELCLHGKDTYLYYIKILDPYLKEWNIT
VDDYDVVIAKLMPMVFD
Download sequence
Identical sequences D2IE21
D2IE21_9PICO

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