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Domain assignment for POLG_AEVL2 from UniProt viral sequences

Domain architecture


Domain assignment details

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Strong hits

Sequence:  POLG_AEVL2
Domain Number 1 Region: 1656-2123
Classification Level Classification E-value
Superfamily DNA/RNA polymerases 2.77e-100
Family RNA-dependent RNA-polymerase 0.00000127
Further Details:      
 
Domain Number 2 Region: 251-492
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 6.86e-47
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.0013
Further Details:      
 
Domain Number 3 Region: 5-241
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 2.19e-45
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.00093
Further Details:      
 
Domain Number 4 Region: 1436-1643
Classification Level Classification E-value
Superfamily Trypsin-like serine proteases 8.57e-37
Family Viral cysteine protease of trypsin fold 0.0000324
Further Details:      
 
Domain Number 5 Region: 485-731
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 1.45e-34
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.0097
Further Details:      
 
Domain Number 6 Region: 1141-1280
Classification Level Classification E-value
Superfamily P-loop containing nucleoside triphosphate hydrolases 0.0000133
Family Extended AAA-ATPase domain 0.042
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) POLG_AEVL2
Sequence length 2134
Comment AC=Q6WQ42; DE=RecName: Full=Genome polyprotein; Contains: RecName: Full=Protein VP0; AltName: Full=VP4-VP2; Contains: RecName: Full=Protein VP4; AltName: Full=P1A; AltName: Full=Virion protein 4; Contains: RecName: Full=Protein VP2; AltName: Full=P1B; AltName: Full=Virion protein 2; Contains: RecName: Full=Protein VP3; AltName: Full=P1C; AltName: Full=Virion protein 3; Contains: RecName: Full=Protein VP1; AltName: Full=P1D; AltName: Full=Virion protein 1; Contains: RecName: Full=Protein 2A; Contains: RecName: Full=Protein 2B; Contains: RecName: Full=Protein 2C; Contains: RecName: Full=Protein 3A; Contains: RecName: Full=Protein 3B; AltName: Full=VPg; Contains: RecName: Full=Picornain 3C; AltName: Full=Protease 3C; Contains: RecName: Full=RNA-directed RNA polymerase 3D-POL; OS=Avian encephalomyelitis virus (strain L2Z) (AEV). OC=Viruses; ssRNA positive-strand viruses, no DNA stage; Picornavirales; OC=Picornaviridae; Tremovirus.
Sequence
MSKLFSTVGRTVDEVLSVLNDEDTESYAGPDRTAVVGGGFLTTVDQSSVSTATMGSLQDV
QYRTAVDIPGSRVTQGERFFLIDQREWNSTQSEWQLLGKIDIVKELLDQSYAVDGLLKYH
SYARFGLDVIVQINPTSFQAGGLIAALVPYDQVDIESIVAMTTYCHGKVNCNINYVVRMK
VPYIYSRGCYNLRNSAYSIWMLVIRVWSRLQLGSGTSTQITITTLARFVDLELHGLSPLV
AQMMRNEFRLSSSSNIVNLANYDDARAKVSLALGQEEFSRDSSSTGGELVHHFSQWTSIP
CLAFTFTFPGTVGPGTHIWSTTVDPFSCNLRASSTVHPTNLSSIAGMFCFWRGDIVFEFQ
VFCTKYHSGRLMFVYVPGDENTKISTLTAKQASTGLTAVFDINGVNSTLVFRCPFISDTP
YRVNPTTHKSLWPYATGKLVCYVYNILNAPASVSPSVSINVYKSAADLELYAPVYGVSPT
NTSIFAQGKEDEGGFFSVPEVEQHVVEDKEPQGPLHVTPFGAVKAMEDPQLARKTPGTFP
ELAPGKPRHTVDHMDLYKFMGRAHYLWGHEFTKTDMQYTFQIPLSPIKEGFVTGTLRWFL
SLFQLYRGSLDITMTFAGKTNVDGIVYFVPEGVAIETEREEQTPLLTLNYKTSVGAIRFN
TGQTTNVQFRIPFYTPLEHIATHSKNAMDSVLGAITTQITNYSAQDEYLQVTYYISFNED
SQFSVPRAVPVVSSFTDTSSKTVMNTYWLDDDELVEESSHSSFDEIEEAQCSKCKMDLGD
IVICSGEKAKHFGVYVGDGVVHVDPEGNATNWFMKRKATVKKSKNLDKWCFALSPRIDRT
LICETANLMVGREVEYDIFVKNCETYARGIASGDYGTKEGEKWKTLLSAVGVAAMTTTMM
AMRHQLLDTSLTKLPQKVGEVTNEVRKILEDTSAGVREFKEKVSSILRKTWPGKTSIKIM
KWTFRIVKMCVGVGLCYAHGWDSKPVTAVVTMFSMDFLDLVIDGIEIGRMIIHELTTPKA
QGLSEINQVLSIAKNAKDVIKMLIEIFCKVIERITGEHGKKIQWAQDKKEEIMNVLERAE
KWITTSDDHSEGIECLKLVRSIQSVIRGEESLKELAGELRAVGTHVLNKLGRLDKPNAPI
LVRAEPTVLYLYGNRGGGKSLASMAIAVKLCKELGISHVEGIYTKPIMSDFWDGYAGQPV
VIMDDLGQSTSDEDWTNFCQLVSSCPLRLNMANLEKKGTQFNSPFIIASSNLSHPCPKTV
YCTDAIARRLHIKVKVSPKEEFSTHAMLDVAKAKKAGAYCNLDCLDFQKISDLASTPVSV
QDIVLALLHTNVDKQTVMGNIIQYWAQSNPREVFDTMAEGKNSGKYLWLFEKIKTSKWYI
LGCVGAALSVSVLGVFAYHMIKNHFRDQQHDQSAYSAAIKPLRVVRLEQSDAQSVVDISN
VVHGNLVRVGVGPNEARIHWLNNGWGVYNTYILMPYHGIKDADVDDDLYIERAGTIYSTN
MKMVQVLFLESREGDLVLINVPRLPKFRDIRNHFSTEENIRRAEGMPGTLCTLDHERFTL
VTESDLKMVEAATYVCEDDKGVRTDISVGRSWKAKACTVAGMCGGALVTSNNKMQNAIVG
IHVAGGAPAISRVITKEMIEEMLKTRAQCSRIWKTEFVEKKISVGSKTKYHKSPLYDFCP
QKVIKCPTKLFYQGEIDVMQVMLAKYSSPIVSEPLGYATVVEAYTNRMVSFFSEPRQLTY
DECINGIEGLDAIDLKTSAGFPYNTLSLKKSDLIINGKKAQRLQQDVEKMEEDLHMNRSI
QVVFTTCAKDELRPLSKGMLGKTRAIKACPVSFTILFRKYLGYALAQIQSHPGFHTGIAV
GVDPDQDWHCMWYSIVTQCDLVVGLDFSNYDASLSPFMIYHAGRVLGQICGLDPRLVDRI
MEPIVNSVHQLGSMRYYVDGSMPSGTPATSVLNSIINVVNISHVLCALEKISVFEVFKLS
KILTYGDDVLFCIKKESLDQKSFPLSSFVQGLKELGMSPTGADKMEVKVTPVHKMSFLKR
TFYVDEWSICHPRISEETVYSMLAWKSDNASMKHVIETSIWFMFHHGPRKYVIFCTCLRG
VLCRVGIGLYIPTYKELEVRYDRLVKDRVIDDSF
Download sequence
Identical sequences Q6WQ42
POLG_AEVL2

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