SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Domain assignment for Q66774_9PICO from UniProt viral sequences

Domain architecture


Domain assignment details

(
show help)
Strong hits

Sequence:  Q66774_9PICO
Domain Number 1 Region: 1785-2243
Classification Level Classification E-value
Superfamily DNA/RNA polymerases 5.44e-115
Family RNA-dependent RNA-polymerase 0.00000000176
Further Details:      
 
Domain Number 2 Region: 11-203
Classification Level Classification E-value
Superfamily Cysteine proteinases 7.15e-81
Family FMDV leader protease 0.00015
Further Details:      
 
Domain Number 3 Region: 210-514
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 2.68e-79
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.00000619
Further Details:      
 
Domain Number 4 Region: 552-746,780-969
Classification Level Classification E-value
Superfamily Positive stranded ssRNA viruses 5e-52
Family Picornaviridae-like VP (VP1, VP2, VP3 and VP4) 0.0000106
Further Details:      
 
Domain Number 5 Region: 1586-1779
Classification Level Classification E-value
Superfamily Trypsin-like serine proteases 6.74e-46
Family Viral cysteine protease of trypsin fold 0.0000251
Further Details:      
 
Domain Number 6 Region: 1211-1383
Classification Level Classification E-value
Superfamily P-loop containing nucleoside triphosphate hydrolases 0.00000000642
Family YjeE-like 0.081
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

(show help)

Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) Q66774_9PICO
Sequence length 2248
Comment AC=Q66774; DE=SubName: Full=Polyprotein; OS=Equine rhinitis A virus. OC=Viruses; ssRNA positive-strand viruses, no DNA stage; Picornavirales; OC=Picornaviridae; Aphthovirus.
Sequence
MMAASKVYRVCEQTLLAGAVRMMDKFLQKKTVFVPQLDKQVRLTGLHNYDNTCWLNALTQ
LTQILGIRLFDEHFGNRGLFTRKTIDWVSDQTGIKDLKSGAPPLVVVYKLWQHGHLDVGT
MEKPRSITLWSGPKVCLSDFWACVSAKPGHAVFYLLTSEGWICVDDKKIYPETPKTEDVL
VFAPYDFESLGKDPPKLHQRYEKAFERLSGAGTSTPTTGNQNMSGNSGSIVQNFYMQQYQ
NSIDADLGDNVISPEGQGSNTSSSTSSSQSSGLGGWFSSLLNLGTKLLADKKTEETTNIE
DRIETTVVGVTIINSQGSVGTTYCYSRPDSKAPSTVSDPVTRLGPTLSRHYTFKVGEWPH
SQSHGHAWICPLPGDKLKKMGSFHEVVKSHHLVKNGWDVVVQVNASFAHSGALCVAAVPE
YKHTHEKALKWSELEEPAYTYQQLSVFPHQLLNLRTNSSVHLVMPYIGPGPTTNLTLHNP
WTIVILILSELTGPGQTVPVTMSVAPIDAMVNGPLPNPEAPIRVVSVPESDSFMSSVPDN
STPLYPKVVVPPRQVPGRFTNFIDVAKQTYSFCSISGKPYFEVTNTSGDEPLFQMDVSLS
AAELHGTYVASLSSFFAQYRGSLNFNFIFTGAAATKAKFLVAFVPPHTAAPKTRDEAMAC
IHAVWDVGLNSAFSFNVPYSSPSDFMAVYSADATVVNVSGWLQVYALTALTSTDIAVNSK
GRVLVAVSAGPDFSLRHPVDLPDKQVTNVGEDGEPGETEPRHALSPVDMHVHTDVSFLLD
RFFDVETIELSNLTGSPTTHLLDPFGSTAQLAWARLLNTCTYFFSDLELSIQFKFTTTPS
SVGEGFVWVKWFPVGAPTKTTDAWQLKGGGNSVRIQKLAVAGLSPTVVFKIAGSRSQACG
FNVPYTSMWRVVPVLYNGWGAPTKEESTYNWLPGAHFGSILLTSDAHDKGGCYLRYRFPR
ASMYCPRPIPPAFTRPADKTRHKFPTNINKQCTNYALLKLAGDVESNPGPTIFSKASADL
NALSTSLGELTGMLKDLKAKAETYSPFYKTAKMLFKLATLAVTAMRTKDPVVVVMLIADF
GLEVFDTGFFFSYFQEKLQPYMKTIPGKISELVTDAATAAAQIPKGVYSFVSSFFETPEG
VVEKQVSLRTVNDIFTLLKNSDWFIKTLVALKKWLTSWFAQEQQADDALYSELEKYPLYK
LKLKEPDTQEEARQWFKDMQQRALAVKDKGLFSLLQIPLVNLPTSRPEPVVCILRGASGQ
GKSYLANLMAQAISLLLVGKQGSVWSCPPDPTYFDGYNGQAVVIMDDLGQNPNGADFKYF
CQMVSTTAFVPPMAHLDDKGIPFTSPVVICTTNLHSSFTPITVSCPEALKRRFRFDVTVS
VKPGFVRTVGSSQLLNLPLALKPAGLPPHPIFENDMPILNGQAVKLALSGGEVTAFELIE
MILSEVQNRQDTHKMPIFKQSWSDLFKKCSTDEEQKMLQFLIDNKDSEILRAFVSERSIL
LHEEYLKWESYMTRRAKFHRLAADFAMFLSILTSLIVIFCLVYSMYQIFKTPDEHSAYDP
ATKPKPKTQEIKTLKIRTETGVPATDLQQSIMKNVQPIELYCDGNLVTDCSALGVYDNSY
LVPLHLFEFDFDTIVLGGRQYKKADCEKVEFELEINGDMVSSDACLLRVPTGPKVRNIVH
LFTNEIELKKMTQITGIMNSPHQARTVFFGSFLTVKKSILTSDGTVMPNVLSYAAQTSRG
YCGAAIVAGSPARIIGIHSAGTGSVAFCSLVSRDALERTLPQKQGNVVRLDDDVRVSVPR
RTKLVKSLAYPVFKPDYGPAPLSQFDKRLADGVKLDEVVFAKHTGDKDISAEDQKWLLRA
AHVYAQRVFARIGFDNQALTEQEAICGIPGLDKMEQDTAPGLPYAQQNKRRKDICDFDKG
QLKGAAKLQKDRFMAGDYSDLVYQSFLKDEIRPLEKVRAGKTRLIDVPPMPHVVVGRQLL
GRFVAKFHEANGFETGSAIGCDPDVDWTRFGLELERYRYVYACDYSRFDANHAADAMRVV
LNYFFSEDHGFDPGVPAFIESLVDSVHAYEEKRFNIYGGLPSGCSCTSILNTVLNNVYIL
AAMMKAFENFEPDDIQVICYGDDCLIASDLEIDFQKLVPVFSSFGQVITTADKTDFFKLT
TLSEVTFLKRAFVPDGAFYKPVMDVKTLEAILSFVRPGTQAEKLLSVAQLAGHCEPEQYE
RLFEPFAGMYYVPTWRDLRLQWLMKLGC
Download sequence
Identical sequences Q66774
Q66774_9PICO gi|21328571|ref|NP_653075.1| NP_653075.1.88786

Jump to [ Top of page · Domain architecture · Domain assignment details · Most Informative Gene Ontologies ]