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Cytokine superfamily domain assignments
in
Homo sapiens

Assignment details

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Homo sapiens (NCBI version) has 67 significant domains in 65 proteins.

     

Sequence ID   Evalue   Region   Family  
gi|10190672|ref|NP_065688.1|   1.49e-48   33-169   Fibroblast growth factors (FGF)  
gi|10190674|ref|NP_065689.1|   5.3e-37   40-167   Fibroblast growth factors (FGF)  
gi|10835145|ref|NP_000567.1|   2.43e-54   122-266   Interleukin-1 (IL-1)  
gi|10835147|ref|NP_000568.1|   4.32e-49   17-158   Interleukin-1 (IL-1)  
gi|11136630|ref|NP_066360.1|   7.96e-74   73-204   Fibroblast growth factors (FGF)  
gi|15055541|ref|NP_149127.1|   0.00000000000412   8-57   Fibroblast growth factors (FGF)  
gi|15055545|ref|NP_149128.1|   0.00000000000667   8-57   Fibroblast growth factors (FGF)  
gi|15055549|ref|NP_149134.1|   0.000000216   77-119   Fibroblast growth factors (FGF)  
gi|15147343|ref|NP_066276.2|   2.36e-45   82-207   Fibroblast growth factors (FGF)  
gi|15147346|ref|NP_149353.1|   3.14e-49   64-207   Fibroblast growth factors (FGF)  
gi|15147348|ref|NP_149354.1|   2.75e-49   53-196   Fibroblast growth factors (FGF)  
gi|15147350|ref|NP_149355.1|   1.81e-49   24-167   Fibroblast growth factors (FGF)  
gi|153285461|ref|NP_001997.5|   6.71e-52   136-286   Fibroblast growth factors (FGF)  
gi|16306543|ref|NP_378668.1|   1.71e-74   16-147   Fibroblast growth factors (FGF)  
gi|20070252|ref|NP_055253.2|   4.71e-27   10-146   Interleukin-1 (IL-1)  
gi|20127524|ref|NP_055254.2|   8.24e-40   57-205   Interleukin-1 (IL-1)  
gi|213417606|ref|NP_001132970.1|   2.94e-53   24-166   Fibroblast growth factors (FGF)  
gi|213417610|ref|NP_001132972.1|   6.28e-53   80-222   Fibroblast growth factors (FGF)  
gi|213417614|ref|NP_001132973.1|   4.52e-53   51-193   Fibroblast growth factors (FGF)  
gi|213417634|ref|NP_001132974.1|   4.52e-53   51-193   Fibroblast growth factors (FGF)  
gi|21614511|ref|NP_004104.3|   1.32e-51   12-152   Fibroblast growth factors (FGF)  
gi|222144221|ref|NP_001138364.1|   7.11e-65   29-152   Fibroblast growth factors (FGF)  
gi|222144271|ref|NP_001138406.1|   7.11e-65   29-152   Fibroblast growth factors (FGF)  
gi|222144273|ref|NP_001138407.1|   7.11e-65   29-152   Fibroblast growth factors (FGF)  
gi|237681091|ref|NP_001153702.1|   0.0000341   412-463   Interleukin-1 (IL-1)  
gi|27894296|ref|NP_775294.1|   5.89e-40   36-184   Interleukin-1 (IL-1)  
gi|27894298|ref|NP_775295.1|   1.96e-32   44-144   Interleukin-1 (IL-1)  
gi|27894300|ref|NP_775296.1|   2.16e-32   65-165   Interleukin-1 (IL-1)  
gi|27894302|ref|NP_775297.1|   5.49e-40   31-179   Interleukin-1 (IL-1)  
gi|27894304|ref|NP_115945.4|   4.71e-42   8-151   Interleukin-1 (IL-1)  
gi|27894307|ref|NP_775184.1|   4.71e-42   8-151   Interleukin-1 (IL-1)  
gi|27894310|ref|NP_775262.1|   4.32e-51   3-155   Interleukin-1 (IL-1)  
gi|27894313|ref|NP_775270.1|   3.02e-49   10-155   Interleukin-1 (IL-1)  
gi|27894317|ref|NP_776213.1|   6.67e-49   38-179   Interleukin-1 (IL-1)  
gi|27894319|ref|NP_776214.1|   6.28e-49   35-176   Interleukin-1 (IL-1)  
gi|27894321|ref|NP_776215.1|   5.49e-49   2-142   Interleukin-1 (IL-1)  
gi|27894330|ref|NP_000566.3|   1.33e-42   122-266   Interleukin-1 (IL-1)  
gi|28872756|ref|NP_787125.1|   4.52e-51   77-218   Fibroblast growth factors (FGF)  
gi|329755303|ref|NP_001193318.1|   3.53e-37   2-103   Fibroblast growth factors (FGF)  
gi|341914780|ref|XP_003403865.1|   7.28e-18   85-202   Fibroblast growth factors (FGF)  
  0.0000377   9-73   Fibroblast growth factors (FGF)  
gi|341915426|ref|XP_002342894.2|   1.2e-17   85-202   Fibroblast growth factors (FGF)  
  0.0000377   9-73   Fibroblast growth factors (FGF)  
gi|4501919|ref|NP_001103.1|   0.0000353   412-463   Interleukin-1 (IL-1)  
gi|4503691|ref|NP_003859.1|   5.3e-55   53-199   Fibroblast growth factors (FGF)  
gi|4503693|ref|NP_003858.1|   3.53e-45   37-178   Fibroblast growth factors (FGF)  
gi|4503695|ref|NP_003853.1|   8.44e-46   39-178   Fibroblast growth factors (FGF)  
gi|4503697|ref|NP_000791.1|   7.11e-65   29-152   Fibroblast growth factors (FGF)  
gi|4503701|ref|NP_001998.1|   2.75e-46   67-205   Fibroblast growth factors (FGF)  
gi|4503705|ref|NP_002000.1|   1.22e-51   57-193   Fibroblast growth factors (FGF)  
gi|4503707|ref|NP_002001.1|   6.28e-55   54-201   Fibroblast growth factors (FGF)  
gi|4504653|ref|NP_001553.1|   2.83e-63   37-192   Interleukin-1 (IL-1)  
gi|4758360|ref|NP_004456.1|   7.85e-51   70-206   Fibroblast growth factors (FGF)  
gi|4758362|ref|NP_004103.1|   1.57e-47   72-215   Fibroblast growth factors (FGF)  
gi|4758366|ref|NP_004105.1|   5.3e-53   70-212   Fibroblast growth factors (FGF)  
gi|4758368|ref|NP_004106.1|   4.32e-51   72-213   Fibroblast growth factors (FGF)  
gi|4826726|ref|NP_005108.1|   8.05e-40   42-175   Fibroblast growth factors (FGF)  
gi|4885233|ref|NP_005238.1|   1.57e-46   36-184   Fibroblast growth factors (FGF)  
gi|5174439|ref|NP_006110.1|   2.16e-49   35-178   Fibroblast growth factors (FGF)  
gi|6912432|ref|NP_036407.1|   4.32e-51   3-155   Interleukin-1 (IL-1)  
gi|73486655|ref|NP_004455.2|   1.41e-49   79-234   Fibroblast growth factors (FGF)  
gi|7657092|ref|NP_055255.1|   9.42e-49   10-156   Interleukin-1 (IL-1)  
gi|7669477|ref|NP_056648.1|   0.0000114   412-478   Interleukin-1 (IL-1)  
gi|7669479|ref|NP_056649.1|   0.0000108   412-478   Interleukin-1 (IL-1)  
gi|9506597|ref|NP_061986.1|   2.75e-35   43-172   Fibroblast growth factors (FGF)  
gi|9665234|ref|NP_062564.1|   2.16e-47   20-167   Interleukin-1 (IL-1)  
gi|9789947|ref|NP_062825.1|   4.98e-80   57-196   Fibroblast growth factors (FGF)  

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Select to display   Genome       Domains   Proteins
No Yes ALL   28248 28248
No Yes Homo sapiens 76_38 Human 99 99
No Yes Pan troglodytes 76_2.1.4 Chimpanzee 38 37
No Yes Gorilla gorilla 76_3.1 Western gorilla 41 41
No Yes Pongo abelii 76_2 Sumatran orangutan 38 38
No Yes Nomascus leucogenys 76_1.0 Northern white-cheeked gibbon 29 29
No Yes Papio anubis 76 Olive baboon 35 35
No Yes Macaca mulatta 76_1 Rhesus monkey 50 50
No Yes Callithrix jacchus 76_3.2.1 White-tufted-ear marmoset 59 58
No Yes Otolemur garnettii 76_3 Small-eared galago 35 34
No Yes Microcebus murinus 76_1 Gray mouse lemur 31 29
No Yes Rattus norvegicus 76_5.0 Norway rat 36 36
No Yes Mus musculus 76_38 House mouse 62 62
No Yes Dipodomys ordii 76_1 Ord's kangaroo rat 23 21
No Yes Ictidomys tridecemlineatus 76_2 Thirteen-lined ground squirrel 35 35
No Yes Heterocephalus glaber v1.7-2 Naked mole-rat 37 36
No Yes Cavia porcellus 76_3 Domestic guinea pig 39 39
No Yes Oryctolagus cuniculus 76_2 Rabbit 29 29
No Yes Ochotona princeps 76 American pika 30 26
No Yes Tupaia belangeri 76 Northern tree shrew 31 29
No Yes Sus scrofa 76_10.2 Pig 32 32
No Yes Bos taurus 76_3.1 Cattle 38 37
No Yes Ovis aries 76_3.1 Sheep 39 38
No Yes Vicugna pacos 76_1 Alpaca 18 18
No Yes Tursiops truncatus 76_1 Bottlenose dolphin 27 27
No Yes Mustela putorius furo 76_1.0 Domestic ferret 30 30
No Yes Ailuropoda melanoleuca 76_1 Giant panda 34 33
No Yes Canis familiaris 76_3.1 Dog 40 39
No Yes Felis catus 76_6.2 Domestic cat 30 29
No Yes Equus caballus 76_2 Horse 33 33
No Yes Myotis lucifugus 76_2.0 Little brown bat 33 33
No Yes Pteropus vampyrus 76_1 Large flying fox 29 28
No Yes Sorex araneus 76_1 European shrew 26 22
No Yes Erinaceus europaeus 76 Western European hedgehog 24 23
No Yes Procavia capensis 76_1 Cape rock hyrax 30 27
No Yes Loxodonta africana 76_3 African savanna elephant 31 31
No Yes Echinops telfairi 76 Small Madagascar hedgehog 23 23
No Yes Dasypus novemcinctus 76_2 Nine-banded armadillo 31 30
No Yes Choloepus hoffmanni 76_1 Hoffmann's two-fingered sloth 12 12
No Yes Macropus eugenii 76_1.0 Tammar wallaby 25 23
No Yes Sarcophilus harrisii 76_7.0 Tasmanian devil 37 36
No Yes Monodelphis domestica 76_5 Gray short-tailed opossum 33 33
No Yes Ornithorhynchus anatinus 76_5 Platypus 26 26
No Yes Saccoglossus kowalevskii v3.0   29 27
No Yes Petromyzon marinus 76_7.0 Sea lamprey 11 9
No Yes Meleagris gallopavo 76_2 Turkey 25 24
No Yes Gallus gallus 76_4 Chicken 24 23
No Yes Anas platyrhynchos 76_1.0 Mallard 24 24
No Yes Taeniopygia guttata 76_3.2.4 Zebra finch 23 22
No Yes Ficedula albicollis 76_1.0 Collared flycatcher 29 28
No Yes Pelodiscus sinensis 76_1.0 Chinese soft-shelled turtle 24 24
No Yes Anolis carolinensis 76_2.0 Green anole 29 28
No Yes Xenopus laevis African clawed frog 55 55
No Yes Xenopus tropicalis 76_4.2 Tropical clawed frog 33 32
No Yes Latimeria chalumnae 76_1 Coelacanth 26 25
No Yes Lepisosteus oculatus 76 Spotted gar 27 26
No Yes Gadus morhua 76_1 Atlantic cod 34 33
No Yes Tetraodon nigroviridis 76_8 Spotted green pufferfish 33 33
No Yes Takifugu rubripes 76_4 Torafugu 61 61
No Yes Gasterosteus aculeatus 76_1 Three-spined stickleback 43 43
No Yes Oryzias latipes 76_1 Japanese medaka 40 40
No Yes Xiphophorus maculatus 76_4.4.2 Southern platyfish 36 36
No Yes Poecilia formosa 76 Amazon molly 37 37
No Yes Oreochromis niloticus 76_1.0 Nile tilapia 38 38
No Yes Astyanax mexicanus 76 Mexican tetra 33 33
No Yes Danio rerio 76_9 Zebrafish 50 50
No Yes Oikopleura dioica   5 5
No Yes Ciona savignyi 76_2.0 Pacific transparent sea squirt 5 5
No Yes Ciona intestinalis 76 Vase tunicate 10 9
No Yes Strongylocentrotus purpuratus v3.1 Purple sea urchin 3 3
No Yes Adineta vaga   3 3
No Yes Octopus bimaculoides 280   3 3
No Yes Crassostrea gigas 22 Pacific oyster 4 3
No Yes Lottia gigantea Owl limpet 4 4
No Yes Helobdella robusta   2 2
No Yes Capitella sp. I   4 2
No Yes Danaus plexippus OGS1.0 Monarch butterfly 3 3
No Yes Heliconius melpomene Postman butterfly 2 2
No Yes Bombyx mori Domestic silkworm 2 2
No Yes Nasonia vitripennis Jewel wasp 1 1
No Yes Apis mellifera 38.2d (Not maintained) Honey bee 2 2
No Yes Harpegnathos saltator v3.3 Jerdon's jumping ant 4 4
No Yes Linepithema humile v1.1 Argentine ant 4 4
No Yes Pogonomyrmex barbatus v1.2 Red harvester ant 4 4
No Yes Solenopsis invicta v.2.2.3 Red fire ant 3 3
No Yes Acromyrmex echinatior v3.8 Panamanian leafcutter ant 4 4
No Yes Atta cephalotes v1.1   4 4
No Yes Camponotus floridanus v3.3 Florida carpenter ant 3 3
No Yes Lucilia cuprina Australian sheep blowfly 4 4
No Yes Drosophila grimshawi 1.3   5 5
No Yes Drosophila willistoni 1.3   3 3
No Yes Drosophila pseudoobscura 2.13   3 3
No Yes Drosophila persimilis 1.3   1 1
No Yes Drosophila suzukii   3 3
No Yes Drosophila yakuba 1.3   3 3
No Yes Drosophila simulans 1.3   3 3
No Yes Drosophila sechellia 1.3   3 3
No Yes Drosophila melanogaster 76_5 Fruit fly 6 6
No Yes Drosophila erecta 1.3   3 3
No Yes Drosophila ananassae 1.3   3 3
No Yes Drosophila virilis 1.2   3 3
No Yes Drosophila mojavensis 1.3   3 3
No Yes Megaselia scalaris 22   2 2
No Yes Culex pipiens quinquefasciatus Southern house mosquito 2 2
No Yes Anopheles darlingi 22 American malaria mosquito 4 4
No Yes Anopheles gambiae 49_3j African malaria mosquito 2 2
No Yes Tribolium castaneum 3.0 Red flour beetle 5 5
No Yes Pediculus humanus corporis (Early assembly) Human body louse 4 4
No Yes Acyrthosiphon pisum Pea aphid 1 1
No Yes Rhodnius prolixus 22   3 3
No Yes Daphnia pulex Common water flea 2 2
No Yes Strigamia maritima 22   3 3
No Yes Tetranychus urticae Two-spotted spider mite 1 1
No Yes Ixodes scapularis (Preliminary) Black-legged tick 3 3
No Yes Pristionchus pacificus   2 2
No Yes Meloidogyne hapla   1 1
No Yes Onchocerca volvulus 22   2 2
No Yes Brugia malayi WS250 Agent of lymphatic filariasis 2 2
No Yes Caenorhabditis japonica   2 2
No Yes Caenorhabditis brenneri   1 1
No Yes Caenorhabditis remanei   2 2
No Yes Caenorhabditis elegans 76_235 Roundworm 3 3
No Yes Caenorhabditis briggsae 2   2 2
No Yes Trichinella spiralis 22   2 2
No Yes Hymenolepis microstoma   2 2
No Yes Echinococcus multilocularis   1 1
No Yes Taenia solium Pork tapeworm 1 1
No Yes Mnemiopsis leidyi Sea walnut 1 1
No Yes Acropora digitifera v1.0   13 13
No Yes Nematostella vectensis 1.0 Starlet sea anemone 17 15
No Yes Hydra vulgaris   11 11
No Yes Amphimedon queenslandica   3 3
No Yes Trichoplax adhaerens   1 1
No Yes Proterospongia sp. ATCC 50818   1 1
No Yes Monosiga brevicollis   2 2
No Yes Trichoderma harzianum CBS 226.95 v1.0   1 1
No Yes Arabidopsis lyrata Lyrate rockcress 1 1
No Yes Arabidopsis thaliana 10 Thale cress 2 2
No Yes Bigelowiella natans CCMP2755 22   1 1
No Yes Giardia lamblia 2.3   1 1
No Yes Fragilariopsis cylindrus   1 1
No Yes Theileria parva   1 1
No Yes Xenopus (Silurana) tropicalis v7.1 (annotation v7.2) Tropical clawed frog 48 48
No Yes Drosophila melanogaster FlyBase 5.12 (FlyBase) Fruit fly 4 4
No Yes Anopheles gambiae VectorBase AgamP3.6 (VectorBase) African malaria mosquito 2 2
No Yes Ascaris suum Victoria/Ghent Pig roundworm 2 2
No Yes Caenorhabditis elegans WormBase WS218 (WormBase) Roundworm 2 2
No Yes Homo sapiens 75_37 (old version GRC) Human 98 98
No Yes Homo sapiens (NCBI version) Human 67 65
No Yes Mus musculus 63_37 (longest transcript per gene) (Duplicate) House mouse 31 31
No Yes Heliconius numata (Incomplete)   1 1
No Yes Loa loa v3.3 (Request) Eye worm 2 2
No Yes Wuchereria bancrofti v1.0 (Request) Agent of lymphatic filariasis 1 1
No Yes Brugia malayi v1.0 (Duplicate) Agent of lymphatic filariasis 2 2
No Yes Homo sapiens 69_37 Human 35 35
No Yes Pan troglodytes 69_2.1.4 Chimpanzee 31 31
No Yes Gorilla gorilla 69_3.1 Western gorilla 35 35
No Yes Pongo abelii 69_2 Sumatran orangutan 33 33
No Yes Nomascus leucogenys 69_1.0 Northern white-cheeked gibbon 31 31
No Yes Macaca mulatta 69_1 Rhesus monkey 34 34
No Yes Callithrix jacchus 69_3.2.1 White-tufted-ear marmoset 33 33
No Yes Otolemur garnettii 69_3 Small-eared galago 35 34
No Yes Microcebus murinus 69_1 Gray mouse lemur 31 29
No Yes Rattus norvegicus 69_3.4 Norway rat 33 33
No Yes Mus musculus 69_38 House mouse 32 32
No Yes Dipodomys ordii 69_1 Ord's kangaroo rat 23 21
No Yes Ictidomys tridecemlineatus 69_2 Thirteen-lined ground squirrel 35 35
No Yes Cavia porcellus 69_3 Domestic guinea pig 35 35
No Yes Oryctolagus cuniculus 69_2 Rabbit 28 28
No Yes Ochotona princeps 69 American pika 30 26
No Yes Tupaia belangeri 69 Northern tree shrew 31 29
No Yes Sus scrofa 69_10.2 Pig 30 30
No Yes Bos taurus 69_3.1 Cattle 34 33
No Yes Vicugna pacos 69_1 Alpaca 18 18
No Yes Tursiops truncatus 69_1 Bottlenose dolphin 27 27
No Yes Mustela putorius furo 69_1.0 Domestic ferret 30 30
No Yes Ailuropoda melanoleuca 69_1 Giant panda 32 31
No Yes Canis familiaris 69_3.1 Dog 32 32
No Yes Felis catus 69 Domestic cat 18 17
No Yes Equus caballus 69_2 Horse 33 33
No Yes Myotis lucifugus 69_2.0 Little brown bat 33 33
No Yes Pteropus vampyrus 69_1 Large flying fox 29 28
No Yes Sorex araneus 69_1 European shrew 26 22
No Yes Erinaceus europaeus 69 Western European hedgehog 24 23
No Yes Procavia capensis 69_1 Cape rock hyrax 30 27
No Yes Loxodonta africana 69_3 African savanna elephant 29 29
No Yes Echinops telfairi 69 Small Madagascar hedgehog 23 23
No Yes Dasypus novemcinctus 69_2 Nine-banded armadillo 23 20
No Yes Choloepus hoffmanni 69_1 Hoffmann's two-fingered sloth 12 12
No Yes Macropus eugenii 69_1.0 Tammar wallaby 25 23
No Yes Sarcophilus harrisii 69_7.0 Tasmanian devil 34 33
No Yes Monodelphis domestica 69_5 Gray short-tailed opossum 32 32
No Yes Ornithorhynchus anatinus 69_5 Platypus 24 24
No Yes Petromyzon marinus 69_7.0 Sea lamprey 9 8
No Yes Meleagris gallopavo 69_2 Turkey 21 20
No Yes Gallus gallus 69_2 Chicken 21 21
No Yes Taeniopygia guttata 69_3.2.4 Zebra finch 23 22
No Yes Pelodiscus sinensis 69_1.0 Chinese soft-shelled turtle 21 21
No Yes Anolis carolinensis 69_2.0 Green anole 27 26
No Yes Xenopus tropicalis 69_4.2 Tropical clawed frog 27 26
No Yes Latimeria chalumnae 69_1 Coelacanth 24 23
No Yes Gadus morhua 69_1 Atlantic cod 34 33
No Yes Tetraodon nigroviridis 69_8 Spotted green pufferfish 33 33
No Yes Takifugu rubripes 69_4 Torafugu 31 31
No Yes Gasterosteus aculeatus 69_1 Three-spined stickleback 33 33
No Yes Oryzias latipes 69_1 Japanese medaka 31 31
No Yes Xiphophorus maculatus 69_4.4.2 Southern platyfish 36 36
No Yes Oreochromis niloticus 69_1.0 Nile tilapia 34 34
No Yes Danio rerio 69_9 Zebrafish 38 38
No Yes Ciona savignyi 69_2.0 Pacific transparent sea squirt 5 5
No Yes Ciona intestinalis 69 Vase tunicate 10 9
No Yes Drosophila melanogaster 69_5 Fruit fly 3 3
No Yes Caenorhabditis elegans 69_215 Roundworm 2 2
No Yes Arabidopsis thaliana 10 Thale cress 1 1
No Yes NCBI 2017_08 genome   12398 12186
No Yes Protozoadb 2010_08 (Protozoadb)   3 3
No Yes STRING v9.0.5 (STRING)   843 835
No Yes Uniprot 2018_03 genome   6821 6688
No Yes NCBI viral sequences (Viral)   99 93
No Yes PDB chains (SCOP 1.75) (PDB)   61 61
No Yes Protein Data Bank (all PDB sequenc)   483 434
No Yes SCOP2 SCOPe CATH ECOD (all domain sequ)   1168 1149
No Yes TargetDB (Targets)   21 21
No Yes UniProt viral sequences (Viral)   95 90

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