SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from Please contact us if you experience any problems.

GTPase activation domain, GAP superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.

All 6 SUPERFAMILY models representing the GTPase activation domain, GAP superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0044148 1112 2005-09-08 d1tx4a_ BCR-homology GTPase activation domain (BH-domain)
0037426 1077 2005-09-08 d1f7ca_ BCR-homology GTPase activation domain (BH-domain)
0050892 3095 2008-09-10 d1xa6a1 BCR-homology GTPase activation domain (BH-domain)
0042243 1042 2005-09-08 d1pbwa_ BCR-homology GTPase activation domain (BH-domain)
0044971 243 2005-09-08 d1wera_ p120GAP domain-like
0041355 228 2005-09-08 d1nf1a_ p120GAP domain-like