SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

TNF-like superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.


All 19 SUPERFAMILY models representing the TNF-like superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0044063 128 2005-09-08 d1tnra_ TNF-like
0053009 23 2008-09-10 d2hewf1 TNF-like
0042351 246 2005-09-08 d1pk6a_ TNF-like
0048776 398 2008-09-10 d1pk6c_ TNF-like
0038234 288 2005-09-08 d1gr3a_ TNF-like
0045792 560 2008-09-10 d1alya_ TNF-like
0054573 116 2010-05-31 d2q1ma1 TNF-like
0043266 384 2005-09-08 d1rj8a_ TNF-like
0053008 22 2008-09-10 d2hevf1 TNF-like
0039757 468 2005-09-08 d1jtzx_ TNF-like
0048519 345 2008-09-10 d1o91a_ TNF-like
0036412 485 2005-09-08 d1dg6a_ TNF-like
0045607 135 2005-09-08 d4tsva_ TNF-like
0053308 585 2008-09-10 d2tnfa_ TNF-like
0042352 267 2005-09-08 d1pk6b_ TNF-like
0051107 448 2008-09-10 d1xu1a_ TNF-like
0039541 139 2005-09-08 d1jh5a_ TNF-like
0046065 393 2008-09-10 d1c28a_ TNF-like
0054584 219 2010-05-31 d2q8oa1 TNF-like