SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

SMAD/FHA domain superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.


All 19 SUPERFAMILY models representing the SMAD/FHA domain superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0040092 110 2005-09-08 d1khua_ SMAD domain
0036359 121 2005-09-08 d1dd1a_ SMAD domain
0047810 157 2008-09-10 d1khxa_ SMAD domain
0043096 641 2005-09-08 d1r21a_ FHA domain
0052027 80 2008-09-10 d2brfa1 FHA domain
0040495 514 2005-09-08 d1lgpa_ FHA domain
0050650 819 2008-09-10 d1wlna1 FHA domain
0037914 626 2005-09-08 d1g3ga_ FHA domain
0044400 77 2005-09-08 d1ujxa_ FHA domain
0052671 2395 2008-09-10 d2ff4a3 FHA domain
0049041 147 2008-09-10 d1qu5a_ FHA domain
0044369 753 2005-09-08 d1uhta_ FHA domain
0052287 1458 2008-09-10 d2cswa1 FHA domain
0041155 631 2005-09-08 d1mzka_ FHA domain
0038313 236 2005-09-08 d1gxca_ FHA domain
0052821 760 2008-09-10 d2g1la1 FHA domain
0043024 333 2005-09-08 d1qwta_ Interferon regulatory factor 3 (IRF3), transactivation domain
0050719 7 2008-09-10 d1wv3a2 EssC N-terminal domain-like
0050718 7 2008-09-10 d1wv3a1 EssC N-terminal domain-like