SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from Please contact us if you experience any problems.

Hedgehog/intein (Hint) domain superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.

All 6 SUPERFAMILY models representing the Hedgehog/intein (Hint) domain superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0035189 95 2005-09-08 d1at0a_ Hedgehog C-terminal (Hog) autoprocessing domain
0035098 112 2005-09-08 d1am2a_ Intein (protein splicing domain)
0048160 373 2008-09-10 d1mi8a_ Intein (protein splicing domain)
0036550 97 2005-09-08 d1dq3a1 Intein (protein splicing domain)
0047695 70 2008-09-10 d1jvaa1 Intein (protein splicing domain)
0038214 49 2005-09-08 d1gppa_ Intein (protein splicing domain)