SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from Please contact us if you experience any problems.

BRCT domain superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.

All 10 SUPERFAMILY models representing the BRCT domain superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0035932 349 2005-09-08 d1cdza_ DNA-repair protein XRCC1
0040406 580 2005-09-08 d1l7ba_ DNA ligase
0039090 258 2005-09-08 d1in1a_ DNA ligase
0039669 296 2005-09-08 d1jnxx2 BRCT domain
0040339 180 2005-09-08 d1l0ba2 BRCT domain
0039668 275 2005-09-08 d1jnxx1 BRCT domain
0040338 350 2005-09-08 d1l0ba1 BRCT domain
0047914 264 2008-09-10 d1kzyc1 53BP1
0047091 64 2008-09-10 d1gzhb2 53BP1
0050485 1034 2008-09-10 d1wf6a_ DNA topoisomerase II binding protein 1, TopBP1