SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from Please contact us if you experience any problems.

Caspase-like superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.

All 8 SUPERFAMILY models representing the Caspase-like superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0037330 263 2005-09-08 d1f1ja_ Caspase catalytic domain
0049359 965 2008-09-10 d1sc3.1 Caspase catalytic domain
0040830 258 2005-09-08 d1m72a_ Caspase catalytic domain
0042978 242 2005-09-08 d1qtn.1 Caspase catalytic domain
0039807 247 2005-09-08 d1jxqa_ Caspase catalytic domain
0036096 254 2005-09-08 d1cp3a_ Caspase catalytic domain
0042519 260 2005-09-08 d1pyo.1 Caspase catalytic domain
0036168 20 2005-09-08 d1cvra2 Gingipain R (RgpB), N-terminal domain