SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from Please contact us if you experience any problems.

SIS domain superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.

All 17 SUPERFAMILY models representing the SIS domain superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0050600 47 2008-09-10 d1wiwa_ double-SIS domain
0049747 2557 2008-09-10 d1tzba_ double-SIS domain
0048203 1996 2008-09-10 d1moqa_ double-SIS domain
0039383 762 2005-09-08 d1j5xa_ double-SIS domain
0047338 621 2008-09-10 d1iata_ Phosphoglucose isomerase, PGI
0046090 616 2008-09-10 d1c7qa_ Phosphoglucose isomerase, PGI
0047090 615 2008-09-10 d1gzda_ Phosphoglucose isomerase, PGI
0049514 1143 2008-09-10 d1t10a_ Phosphoglucose isomerase, PGI
0046385 1154 2008-09-10 d1dqra_ Phosphoglucose isomerase, PGI
0049756 1148 2008-09-10 d1u0fa_ Phosphoglucose isomerase, PGI
0044035 859 2005-09-08 d1tk9a_ mono-SIS domain
0048425 2082 2008-09-10 d1nria_ mono-SIS domain
0039507 988 2005-09-08 d1jeoa_ mono-SIS domain
0050197 2200 2008-09-10 d1vima_ mono-SIS domain
0045017 848 2005-09-08 d1x94a_ mono-SIS domain
0048077 3362 2008-09-10 d1m3sa_ mono-SIS domain
0050875 1968 2008-09-10 d1x92a_ mono-SIS domain