SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Cysteine proteinases superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.


All 75 SUPERFAMILY models representing the Cysteine proteinases superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0046317 1708 2008-09-10 d1deua_ Papain-like
0048105 1727 2008-09-10 d1m6da_ Papain-like
0036163 6 2005-09-08 d1cv8a_ Papain-like
0039241 1203 2005-09-08 d1iwda_ Papain-like
0043495 1140 2005-09-08 d1s4va_ Papain-like
0045662 1206 2005-09-08 d8pch.1 Papain-like
0047662 1788 2008-09-10 d1jqpa2 Papain-like
0035021 1180 2005-09-08 d1aeca_ Papain-like
0045204 708 2005-09-08 d2cb5a_ Papain-like
0046780 1741 2008-09-10 d1fh0a_ Papain-like
0048736 1858 2008-09-10 d1pcia_ Papain-like
0053371 1836 2008-09-10 d7pcka_ Papain-like
0046209 1753 2008-09-10 d1cs8a_ Papain-like
0047807 1822 2008-09-10 d1khqa_ Papain-like
0051746 3505 2008-09-10 d2acta_ Papain-like
0045544 1100 2005-09-08 d3pbha_ Papain-like
0047010 1767 2008-09-10 d1gloa_ Papain-like
0048933 1783 2008-09-10 d1qdqa_ Papain-like
0051417 3585 2008-09-10 d1yvba1 Papain-like
0040950 1161 2005-09-08 d1mira_ Papain-like
0046688 1661 2008-09-10 d1f2aa_ Papain-like
0048477 1874 2008-09-10 d1o0ea_ Papain-like
0050999 1647 2008-09-10 d1xkga1 Papain-like
0046199 1733 2008-09-10 d1cqda_ Papain-like
0047735 1790 2008-09-10 d1k3b.1 Papain-like
0042510 28 2005-09-08 d1pxva_ Papain-like
0045515 492 2005-09-08 d3gcba_ Papain-like
0046968 1775 2008-09-10 d1gece_ Papain-like
0048830 64 2008-09-10 d1pvja_ Papain-like
0051256 1775 2008-09-10 d1yala_ Papain-like
0053622 3678 2010-05-31 d1vsna1 Papain-like
0042902 16 2005-09-08 d1qola_ FMDV leader protease
0049065 970 2008-09-10 d1qxpa4 Calpain large subunit, catalytic domain (domain II)
0051557 974 2008-09-10 d1zcma1 Calpain large subunit, catalytic domain (domain II)
0036392 232 2005-09-08 d1df0a3 Calpain large subunit, catalytic domain (domain II)
0040066 230 2005-09-08 d1kful3 Calpain large subunit, catalytic domain (domain II)
0051581 973 2008-09-10 d1ziva1 Calpain large subunit, catalytic domain (domain II)
0040429 174 2005-09-08 d1l9na4 Transglutaminase core
0053901 830 2010-05-31 d2f4ma1 Transglutaminase core
0037874 173 2005-09-08 d1g0da4 Transglutaminase core
0040275 221 2005-09-08 d1kv3a4 Transglutaminase core
0050793 1372 2008-09-10 d1x3za1 Transglutaminase core
0037324 232 2005-09-08 d1f13a4 Transglutaminase core
0052043 247 2008-09-10 d2bsza1 Arylamine N-acetyltransferase
0036721 102 2005-09-08 d1e2ta_ Arylamine N-acetyltransferase
0050362 426 2008-09-10 d1w4ta1 Arylamine N-acetyltransferase
0038312 104 2005-09-08 d1gx3a_ Arylamine N-acetyltransferase
0050922 415 2008-09-10 d1xd3a_ Ubiquitin carboxyl-terminal hydrolase UCH-L
0052516 412 2008-09-10 d2etla1 Ubiquitin carboxyl-terminal hydrolase UCH-L
0036067 122 2005-09-08 d1cmxa_ Ubiquitin carboxyl-terminal hydrolase UCH-L
0037200 422 2005-09-08 d1euva_ Adenain-like
0044004 404 2005-09-08 d1th0a_ Adenain-like
0052181 1212 2008-09-10 d2ckha1 Adenain-like
0051992 613 2008-09-10 d2bkra1 Adenain-like
0035230 85 2005-09-08 d1avpa_ Adenain-like
0039200 9 2005-09-08 d1iu4a_ Microbial transglutaminase
0051855 3367 2008-09-10 d2ayna1 Ubiquitin carboxyl-terminal hydrolase, UCH
0041295 1022 2005-09-08 d1nbfa_ Ubiquitin carboxyl-terminal hydrolase, UCH
0052887 1849 2008-09-10 d2gfoa1 Ubiquitin carboxyl-terminal hydrolase, UCH
0044814 1003 2005-09-08 d1vjva_ Ubiquitin carboxyl-terminal hydrolase, UCH
0054026 3461 2010-05-31 d2hd5a1 Ubiquitin carboxyl-terminal hydrolase, UCH
0044406 18 2005-09-08 d1ukfa_ Avirulence protein Avrpph3
0043989 89 2005-09-08 d1tffa_ Ubiquitin thiolesterase protein OTUB2 (Otubain-2)
0051162 29 2008-09-10 d1y08a_ IgG-specific endopeptidase IdeS (Sib38)
0053117 104 2008-09-10 d2im9a1 Lpg0564-like
0052048 129 2008-09-10 d2bu3a1 Phytochelatin synthase
0053121 202 2008-09-10 d2io8a2 CHAP domain
0052526 2065 2008-09-10 d2evra2 NlpC/P60
0053877 2 2010-05-31 d2ebfx3 PMT C-terminal domain like
0054137 6 2010-05-31 d2ihoa2 MOA C-terminal domain-like
0054051 7 2010-05-31 d2hlya1 Atu2299-like
0054201 55 2010-05-31 d2j7qa1 M48USP-like
0054133 425 2010-05-31 d2if6a1 YiiX-like
0054753 289 2010-05-31 d2z0da1 Autophagin-like
0054476 287 2010-05-31 d2p82a1 Autophagin-like