SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Class II aaRS and biotin synthetases superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.


All 38 SUPERFAMILY models representing the Class II aaRS and biotin synthetases superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0035444 973 2005-09-08 d1bbua2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0042520 693 2005-09-08 d1pysa_ Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0046922 2530 2008-09-10 d1g51a3 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0035005 737 2005-09-08 d1adja2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0041422 1043 2005-09-08 d1nj1a3 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0046437 2185 2008-09-10 d1e1oa2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0049183 856 2008-09-10 d1riqa2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0052835 21 2008-09-10 d2g4ca2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0037947 523 2005-09-08 d1g5ha2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0045676 264 2008-09-10 d12asa_ Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0048309 2265 2008-09-10 d1n9wa2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0035382 359 2005-09-08 d1b76a2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0041634 984 2005-09-08 d1nyra4 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0046638 2692 2008-09-10 d1evla2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0049994 1811 2008-09-10 d1usya_ Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0040152 837 2005-09-08 d1kmma2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0046052 2554 2008-09-10 d1c0aa3 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0048934 3333 2008-09-10 d1qe0a2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0051519 3185 2008-09-10 d1z7ma1 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0042525 458 2005-09-08 d1pysb5 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0047165 2510 2008-09-10 d1hc7a2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0035194 362 2005-09-08 d1atia2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0041426 790 2005-09-08 d1nj8a3 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0046597 2124 2008-09-10 d1eova2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0049378 2093 2008-09-10 d1seta2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0039382 511 2005-09-08 d1j5wa_ Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0045899 2215 2008-09-10 d1b8aa2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0048394 2404 2008-09-10 d1nnha_ Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0050706 3313 2008-09-10 d1wu7a2 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
0050689 1133 2008-09-10 d1wqwa2 Biotin holoenzyme synthetase
0035568 304 2005-09-08 d1biaa3 Biotin holoenzyme synthetase
0050295 956 2008-09-10 d1vqza2 LplA-like
0054461 581 2010-05-31 d2p5ia1 LplA-like
0053767 1004 2010-05-31 d2c8ma1 LplA-like
0050375 535 2008-09-10 d1w66a1 LplA-like
0054444 538 2010-05-31 d2p0la1 LplA-like
0053636 832 2010-05-31 d1x2ga2 LplA-like
0053816 36 2010-05-31 d2ddza1 PH0223-like