SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

E set domains superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.


All 107 SUPERFAMILY models representing the E set domains superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0047387 159 2008-09-10 d1imhc1 NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
0052345 722 2008-09-10 d2cxka1 NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
0034795 193 2005-09-08 d1a02n1 NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
0045704 526 2008-09-10 d1a3qa1 NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
0042075 117 2005-09-08 d1oy3c_ NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
0046996 413 2008-09-10 d1gjia1 NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
0047381 496 2008-09-10 d1iknc_ NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
0049691 149 2008-09-10 d1ttua1 NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
0047116 48 2008-09-10 d1h3ga1 E-set domains of sugar-utilizing enzymes
0051973 1287 2008-09-10 d2bhua1 E-set domains of sugar-utilizing enzymes
0046137 1105 2008-09-10 d1cgta1 E-set domains of sugar-utilizing enzymes
0046527 201 2008-09-10 d1edqa1 E-set domains of sugar-utilizing enzymes
0049897 4 2008-09-10 d1ug9a2 E-set domains of sugar-utilizing enzymes
0045945 564 2008-09-10 d1bf2a1 E-set domains of sugar-utilizing enzymes
0048722 372 2008-09-10 d1pama1 E-set domains of sugar-utilizing enzymes
0042695 25 2005-09-08 d1qbaa1 E-set domains of sugar-utilizing enzymes
0046167 116 2008-09-10 d1clca2 E-set domains of sugar-utilizing enzymes
0047072 186 2008-09-10 d1gvia1 E-set domains of sugar-utilizing enzymes
0047590 126 2008-09-10 d1ji1a1 E-set domains of sugar-utilizing enzymes
0051961 319 2008-09-10 d2bema_ E-set domains of sugar-utilizing enzymes
0053915 102 2010-05-31 d2fhfa2 E-set domains of sugar-utilizing enzymes
0046503 157 2008-09-10 d1ea9c1 E-set domains of sugar-utilizing enzymes
0049731 293 2008-09-10 d1txka1 E-set domains of sugar-utilizing enzymes
0046264 504 2008-09-10 d1d3ca1 E-set domains of sugar-utilizing enzymes
0046681 38 2008-09-10 d1f1sa2 E-set domains of sugar-utilizing enzymes
0050400 7 2008-09-10 d1w8oa1 E-set domains of sugar-utilizing enzymes
0046150 1032 2008-09-10 d1ciua1 E-set domains of sugar-utilizing enzymes
0046558 712 2008-09-10 d1eh9a1 E-set domains of sugar-utilizing enzymes
0047489 185 2008-09-10 d1j0ha1 E-set domains of sugar-utilizing enzymes
0048958 631 2008-09-10 d1qhoa1 E-set domains of sugar-utilizing enzymes
0049996 112 2008-09-10 d1ut9a2 E-set domains of sugar-utilizing enzymes
0053914 1857 2010-05-31 d2fhfa1 E-set domains of sugar-utilizing enzymes
0036195 405 2005-09-08 d1cyga1 E-set domains of sugar-utilizing enzymes
0046021 154 2008-09-10 d1bvza1 E-set domains of sugar-utilizing enzymes
0047739 257 2008-09-10 d1k3ia1 E-set domains of sugar-utilizing enzymes
0048116 2201 2008-09-10 d1m7xa1 E-set domains of sugar-utilizing enzymes
0052060 3 2008-09-10 d2bvya1 E-set domains of sugar-utilizing enzymes
0047990 422 2008-09-10 d1llaa3 Arthropod hemocyanin, C-terminal domain
0053584 417 2010-05-31 d1hc1a3 Arthropod hemocyanin, C-terminal domain
0048589 2941 2008-09-10 d1okea1 Class II viral fusion proteins C-terminal domain
0049329 2968 2008-09-10 d1s6na_ Class II viral fusion proteins C-terminal domain
0051500 2917 2008-09-10 d1z66a1 Class II viral fusion proteins C-terminal domain
0049480 2917 2008-09-10 d1svba1 Class II viral fusion proteins C-terminal domain
0049153 312 2008-09-10 d1rera1 Class II viral fusion proteins C-terminal domain
0048773 2953 2008-09-10 d1pjwa_ Class II viral fusion proteins C-terminal domain
0047385 34 2008-09-10 d1im3d_ Cytomegalovirus protein US2
0048564 914 2008-09-10 d1ogpa1 Molybdenum-containing oxidoreductases-like dimerisation domain
0049432 870 2008-09-10 d1soxa1 Molybdenum-containing oxidoreductases-like dimerisation domain
0047877 233 2008-09-10 d1ktja_ ML domain
0048348 235 2008-09-10 d1nepa_ ML domain
0051134 237 2008-09-10 d1xwva_ ML domain
0040240 148 2005-09-08 d1kshb_ RhoGDI-like
0046368 194 2008-09-10 d1doab_ RhoGDI-like
0046854 188 2008-09-10 d1fsoa_ RhoGDI-like
0047834 188 2008-09-10 d1kmta_ RhoGDI-like
0046393 194 2008-09-10 d1ds6b_ RhoGDI-like
0046675 299 2008-09-10 d1f13a1 Transglutaminase N-terminal domain
0047946 304 2008-09-10 d1l9na1 Transglutaminase N-terminal domain
0047884 301 2008-09-10 d1kv3a1 Transglutaminase N-terminal domain
0046892 302 2008-09-10 d1g0da1 Transglutaminase N-terminal domain
0052398 4303 2008-09-10 d2d7pa1 Filamin repeat (rod domain)
0052458 4364 2008-09-10 d2dlga1 Filamin repeat (rod domain)
0054189 2853 2010-05-31 d2j3sa2 Filamin repeat (rod domain)
0048942 4149 2008-09-10 d1qfha2 Filamin repeat (rod domain)
0052395 4382 2008-09-10 d2d7ma1 Filamin repeat (rod domain)
0052436 4402 2008-09-10 d2diba1 Filamin repeat (rod domain)
0050647 4270 2008-09-10 d1wlha1 Filamin repeat (rod domain)
0052028 4362 2008-09-10 d2brqa1 Filamin repeat (rod domain)
0052433 4367 2008-09-10 d2di8a1 Filamin repeat (rod domain)
0052468 4216 2008-09-10 d2dmca1 Filamin repeat (rod domain)
0050024 4275 2008-09-10 d1v05a_ Filamin repeat (rod domain)
0052397 4360 2008-09-10 d2d7oa1 Filamin repeat (rod domain)
0052444 4382 2008-09-10 d2dj4a1 Filamin repeat (rod domain)
0048941 4324 2008-09-10 d1qfha1 Filamin repeat (rod domain)
0052435 4340 2008-09-10 d2diaa1 Filamin repeat (rod domain)
0052025 4386 2008-09-10 d2bp3a1 Filamin repeat (rod domain)
0052399 4324 2008-09-10 d2d7qa1 Filamin repeat (rod domain)
0052467 4200 2008-09-10 d2dmba1 Filamin repeat (rod domain)
0052396 4385 2008-09-10 d2d7na1 Filamin repeat (rod domain)
0052437 4384 2008-09-10 d2dica1 Filamin repeat (rod domain)
0052434 4292 2008-09-10 d2di9a1 Filamin repeat (rod domain)
0046920 383 2008-09-10 d1g4ma2 Arrestin/Vps26-like
0035950 136 2005-09-08 d1cf1a1 Arrestin/Vps26-like
0046127 421 2008-09-10 d1cf1a2 Arrestin/Vps26-like
0046919 228 2008-09-10 d1g4ma1 Arrestin/Vps26-like
0046222 14 2008-09-10 d1cvra1 Gingipain R (RgpB), C-terminal domain
0046563 51 2008-09-10 d1ehxa_ Cellulosomal scaffoldin protein CipC, module x2.1
0047603 20 2008-09-10 d1jjua3 Quinohemoprotein amine dehydrogenase A chain, domains 4 and 5
0047633 22 2008-09-10 d1jmxa4 Quinohemoprotein amine dehydrogenase A chain, domains 4 and 5
0039645 33 2005-09-08 d1jmxa3 Quinohemoprotein amine dehydrogenase A chain, domains 4 and 5
0047604 22 2008-09-10 d1jjua4 Quinohemoprotein amine dehydrogenase A chain, domains 4 and 5
0047131 587 2008-09-10 d1h6ua1 Internalin Ig-like domain
0047130 573 2008-09-10 d1h6ta1 Internalin Ig-like domain
0048504 571 2008-09-10 d1o6va1 Internalin Ig-like domain
0048306 593 2008-09-10 d1n9pa_ Cytoplasmic domain of inward rectifier potassium channel
0048708 586 2008-09-10 d1p7ba1 Cytoplasmic domain of inward rectifier potassium channel
0051013 586 2008-09-10 d1xl4a1 Cytoplasmic domain of inward rectifier potassium channel
0048082 355 2008-09-10 d1m42a_ Copper resistance protein C (CopC, PcoC)
0048052 352 2008-09-10 d1lyqa_ Copper resistance protein C (CopC, PcoC)
0044234 384 2005-09-08 d1uadc_ Other IPT/TIG domains
0050094 192 2008-09-10 d1v8ha1 SoxZ-like
0051882 122 2008-09-10 d2b20a1 Enterochelin esterase N-terminal domain-like
0053899 1085 2010-05-31 d2f15a1 AMPK-beta glycogen binding domain-like
0054614 622 2010-05-31 d2qlvb1 AMPK-beta glycogen binding domain-like
0053661 1123 2010-05-31 d1z0na1 AMPK-beta glycogen binding domain-like
0054572 518 2010-05-31 d2q0zx2 Sec63 C-terminal domain-like
0054967 99 2010-05-31 d3es6b1 SVA-like