SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from Please contact us if you experience any problems.

PAP/OAS1 substrate-binding domain superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.

All 6 SUPERFAMILY models representing the PAP/OAS1 substrate-binding domain superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0046739 114 2008-09-10 d1fa0a3 Poly(A) polymerase, PAP, middle domain
0037393 111 2005-09-08 d1f5aa3 Poly(A) polymerase, PAP, middle domain
0042506 77 2005-09-08 d1px5a1 2'-5'-oligoadenylate synthetase 1, OAS1, second domain
0043167 38 2005-09-08 d1r89a1 Archaeal tRNA CCA-adding enzyme substrate-binding domain
0051903 367 2008-09-10 d2b4va1 RNA editing terminal uridyl transferase 2, RET2, domain 2
0054491 99 2010-05-31 d2pbea1 AadK C-terminal domain-like