SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from Please contact us if you experience any problems.

SET domain superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.

All 5 SUPERFAMILY models representing the SET domain superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0041233 367 2005-09-08 d1n6aa2 Histone lysine methyltransferases
0048228 1977 2008-09-10 d1mvha_ Histone lysine methyltransferases
0048183 2185 2008-09-10 d1ml9a_ Histone lysine methyltransferases
0048273 1937 2008-09-10 d1n3ja_ Viral histone H3 Lysine 27 Methyltransferase
0040998 623 2005-09-08 d1mlva2 RuBisCo LSMT catalytic domain