SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Disease Ontology (DO): primary biliary cirrhosis

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   disease [DOID:4] <8>
+ + + + + 5:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + + 4:   immune system disease [DOID:2914] <4>(39|47) (42|27|16)
+ + + + 4:   gastrointestinal system disease [DOID:77] <14>(33|43) (35|18|5)
+ + + 3:   hypersensitivity reaction disease [DOID:0060056] <5>(35|46) (37|23|14)
+ + + 3:   hepatobiliary disease [DOID:3118] <2>(8|11) (8|6|1)
+ + 2:   liver disease [DOID:409] <8>(8|10) (8|6|1)
+ + 2:   hypersensitivity reaction type II disease [DOID:417] <26>(33|43) (35|23|14)
+ 1:   autoimmune disease of urogenital tract [DOID:0060049] <1>(4|2) (4|3|1)
+ 1:   liver cirrhosis [DOID:5082] <2>(5|3) (5|3|1)
0:   primary biliary cirrhosis [DOID:12236](4|2) (4|3|1)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
Single hybrid motif0.000005828Direct
CoA-dependent acyltransferases0.00001077Direct
ABC transporter transmembrane region0.0007467Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Biotinyl/lipoyl-carrier proteins and domains0.000004908Direct
ABC transporter transmembrane region0.0003429Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
Single hybrid motif0.000003137Direct
CoA-dependent acyltransferases0.000005918Direct
ABC transporter transmembrane region0.0004604Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47005,52777
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    51230,47005
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 0Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0004604Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    51230,47005,52777
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)