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Disease Ontology (DO): primary immunodeficiency disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   disease [DOID:4] <8>
+ + 2:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ 1:   immune system disease [DOID:2914] <4>(39|47) (42|27|16)
0:   primary immunodeficiency disease [DOID:612] <8>(6|3) (6|3|0)
- 1:   complement deficiency [DOID:626] <12>(0|0) (0|0|0)
- 1:   B cell deficiency [DOID:2115] <7>(3|2) (3|1|0)
- 1:   combined T cell and B cell immunodeficiency [DOID:628] <5>(0|1) (0|1|0)
- 1:   familial cold autoinflammatory syndrome [DOID:0090061] <4>(0|0) (0|0|0)
- 1:   lymphoproliferative syndrome [DOID:0060704] <4>(0|0) (0|0|0)
- 1:   T cell deficiency [DOID:11200] <2>(0|0) (0|0|0)
- 1:   phagocyte bactericidal dysfunction [DOID:3262] <1>(3|0) (3|1|0)
- 1:   WHIM syndrome [DOID:0060591](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.01628Inherited
SET domain0.03477Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.06464Inherited
Riboflavin synthase domain-like0.06464Inherited
TNF-like0.09383Inherited
4-helical cytokines0.2577Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
TNF receptor-like0.05408Inherited
TNF-like0.06948Inherited
C1 set domains (antibody constant domain-like)0.4258Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TNF receptor-like0.01161Inherited
SET domain0.02593Inherited
Riboflavin synthase domain-like0.04991Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.04991Inherited
TNF-like0.07426Inherited
4-helical cytokines0.2167Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0.0005902Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.006572Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.05723Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)