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Disease Ontology (DO): severe combined immunodeficiency

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   disease [DOID:4] <8>
+ + + + 4:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + 3:   immune system disease [DOID:2914] <4>(39|47) (42|27|16)
+ + 2:   primary immunodeficiency disease [DOID:612] <8>(6|3) (6|3|0)
+ 1:   combined T cell and B cell immunodeficiency [DOID:628] <5>(0|1) (0|1|0)
0:   severe combined immunodeficiency [DOID:627] <21>(0|1) (0|1|0)
- 1:   CD3delta deficiency [DOID:0060016](0|0) (0|0|0)
- 1:   CD3epsilon deficiency [DOID:0060017](0|0) (0|0|0)
- 1:   CD3gamma deficiency [DOID:0060018](0|0) (0|0|0)
- 1:   CD3zeta deficiency [DOID:0060007](0|0) (0|0|0)
- 1:   CD45 deficiency [DOID:0060014](0|0) (0|0|0)
- 1:   MHC class I deficiency [DOID:0060009](0|0) (0|0|0)
- 1:   MHC class II deficiency [DOID:5812](0|0) (0|0|0)
- 1:   Omenn syndrome [DOID:0060010](0|0) (0|0|0)
- 1:   T-cell immunodeficiency, congenital alopecia, and nail dystrophy [DOID:0060769](0|0) (0|0|0)
- 1:   adenosine deaminase deficiency [DOID:5810](0|0) (0|0|0)
- 1:   artemis deficiency [DOID:0060006](0|0) (0|0|0)
- 1:   coronin-1A deficiency [DOID:0060019](0|0) (0|0|0)
- 1:   gamma chain deficiency [DOID:0060013](0|0) (0|0|0)
- 1:   interleukin-7 receptor alpha deficiency [DOID:0060015](0|0) (0|0|0)
- 1:   janus kinase-3 deficiency [DOID:0060008](0|0) (0|0|0)
- 1:   recombinase activating gene 1 deficiency [DOID:0060011](0|0) (0|0|0)
- 1:   recombinase activating gene 2 deficiency [DOID:0060012](0|0) (0|0|0)
- 1:   reticular dysgenesis [DOID:0060020](0|0) (0|0|0)
- 1:   severe combined immunodeficiency with sensitivity to ionizing radiation [DOID:0090012](0|0) (0|0|0)
- 1:   severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-pos [DOID:0090013](0|0) (0|0|0)
- 1:   severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-pos [DOID:0090014](0|0) (0|0|0)


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
C1 set domains (antibody constant domain-like)0.0008321Direct


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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.0003868Direct