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Enzyme Commission (EC): Transferases
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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: EC Hierarchy (from IntEnz release 70)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this EC term (Not in SDEC)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Phosphohistidine domain | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| HPr-like | 0 | DIRECT |
| CoA-transferase family III (CaiB/BaiF) | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| QueA-like | 0 | DIRECT |
| Pyridoxine 5'-phosphate synthase | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| NusB-like | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| tRNA-guanine transglycosylase | 0 | DIRECT |
| Prenyltransferase-like | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Retrovirus capsid dimerization domain-like | 0 | DIRECT |
| Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | DIRECT |
| ApbE-like | 0 | DIRECT |
| Malate synthase G | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| L domain-like | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | DIRECT |
| OMPA-like | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
| GlnB-like | 0 | DIRECT |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
| DNA polymerase III chi subunit | 0 | DIRECT |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| HAMP domain-like | 0 | DIRECT |
| PilZ domain-like | 0 | DIRECT |
| CheW-like | 0 | DIRECT |
| Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
| ARM repeat | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| Methyl-coenzyme M reductase subunits | 0 | DIRECT |
| PPK N-terminal domain-like | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Pentapeptide repeat-like | 0 | DIRECT |
| Riboflavin kinase-like | 0 | DIRECT |
| Methionine synthase activation domain-like | 0 | DIRECT |
| TAF(II)230 TBP-binding fragment | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | DIRECT |
| NadA-like | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Retroviral matrix proteins | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
| DAK1/DegV-like | 0 | DIRECT |
| PK C-terminal domain-like | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| alpha-D-mannose-specific plant lectins | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| Glycerate kinase I | 0 | DIRECT |
| MoeA N-terminal region -like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| ThiG-like | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| Pre-PUA domain | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
| Methionine synthase domain | 0 | DIRECT |
| BAR/IMD domain-like | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| TTHA0583/YokD-like | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| Molybdopterin synthase subunit MoaE | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| YgbK-like | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| RNA polymerase subunits | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| DmpA/ArgJ-like | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| Ankyrin repeat | 0 | DIRECT |
| PTS system fructose IIA component-like | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| Trimerization domain of TRAF | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| E set domains | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Monomethylamine methyltransferase MtmB | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| Sporulation response regulatory protein Spo0B | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Tetrapyrrole methylase | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| RNA polymerase subunit RPB10 | 0 | DIRECT |
| RPB5-like RNA polymerase subunit | 0 | DIRECT |
| MoeA C-terminal domain-like | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| PsbU/PolX domain-like | 0 | DIRECT |
| PTS IIb component | 0 | DIRECT |
| PLP-dependent transferases | 0 | DIRECT |
| NRDP1 C-terminal domain-like | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| Thymidylate synthase-complementing protein Thy1 | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| PHP domain-like | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
| Zinc hairpin stack | 0 | DIRECT |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Immunoglobulin | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0 | DIRECT |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | DIRECT |
| Cobalamin adenosyltransferase-like | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| Insert subdomain of RNA polymerase alpha subunit | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| PHP14-like | 0 | DIRECT |
| Lumazine synthase | 0 | DIRECT |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 0 | DIRECT |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Leucine zipper domain | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Glucose permease domain IIB | 0 | DIRECT |
| Cyclin-like | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
| Phosphoglycerate kinase | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| CheY-binding domain of CheA | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| SSo0622-like | 0 | DIRECT |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| Siroheme synthase middle domains-like | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| Trm112p-like | 0 | DIRECT |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
| Thiamin pyrophosphokinase, catalytic domain | 0 | DIRECT |
| PTS system IIB component-like | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | DIRECT |
| AF1531-like | 0 | DIRECT |
| Poly(A) polymerase catalytic subunit-like | 0 | DIRECT |
| RING/U-box | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| CofD-like | 0 | DIRECT |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | DIRECT |
| FAT domain of focal adhesion kinase | 0 | DIRECT |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | DIRECT |
| YojJ-like | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| Protein kinase-like (PK-like) | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| Docking domain B of the erythromycin polyketide synthase (DEBS) | 0 | DIRECT |
| SAM/Pointed domain | 0 | DIRECT |
| C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
| Aspartate/ornithine carbamoyltransferase | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Thiamin phosphate synthase | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| Carbamate kinase-like | 0 | DIRECT |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | DIRECT |
| CbiD-like | 0 | DIRECT |
| CHY zinc finger-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | DIRECT |
| RPB6/omega subunit-like | 0 | DIRECT |
| AFP III-like domain | 0 | DIRECT |
| Poly A polymerase C-terminal region-like | 0 | DIRECT |
| DhaL-like | 0 | DIRECT |
| PH domain-like | 0.00000000000000277 | DIRECT |
| Fic-like | 0.000000000000006994 | DIRECT |
| Sensory domain-like | 0.00000000000004896 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0.0000000000001514 | DIRECT |
| TRAF domain-like | 0.0000000000005217 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0.0000000000006668 | DIRECT |
| Molybdenum cofactor biosynthesis proteins | 0.0000000000006732 | DIRECT |
| RNI-like | 0.000000000001847 | DIRECT |
| FYVE/PHD zinc finger | 0.000000000009672 | DIRECT |
| Bromodomain | 0.00000000001264 | DIRECT |
| beta-beta-alpha zinc fingers | 0.00000000001664 | DIRECT |
| L30e-like | 0.00000000003133 | DIRECT |
| CCCH zinc finger | 0.00000000007581 | DIRECT |
| Homeodomain-like | 0.0000000001152 | DIRECT |
| Ricin B-like lectins | 0.0000000005723 | DIRECT |
| ClpP/crotonase | 0.0000000007921 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0.000000002565 | DIRECT |
| Phospholipase D/nuclease | 0.000000005204 | DIRECT |
| WW domain | 0.000000005545 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0.0000001122 | DIRECT |
| Single hybrid motif | 0.0000001684 | DIRECT |
| HprK N-terminal domain-like | 0.0000001793 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.0000002019 | DIRECT |
| Chromo domain-like | 0.0000009356 | DIRECT |
| post-AAA+ oligomerization domain-like | 0.000001016 | DIRECT |
| Ubiquitin-like | 0.000002716 | DIRECT |
| WD40 repeat-like | 0.000007361 | DIRECT |
| NHL repeat | 0.00001305 | DIRECT |
| PIN domain-like | 0.00001868 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.00006736 | DIRECT |
| Second domain of FERM | 0.00008173 | DIRECT |
| GckA/TtuD-like | 0.0001011 | DIRECT |
| Glycosyl hydrolase domain | 0.0001532 | DIRECT |
| ACP-like | 0.0001549 | DIRECT |
| TPR-like | 0.0002792 | DIRECT |
| SMAD/FHA domain | 0.0002936 | DIRECT |
| GAF domain-like | 0.0004318 | DIRECT |
| EF-hand | 0.0006043 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0.001014 | INHERITED FROM: 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase || Nucleoside deoxyribosyltransferase || Transferring other glycosyl groups || Glycosyltransferases |
| beta-sandwich domain of Sec23/24 | 0.001231 | INHERITED FROM: Protein-serine/threonine kinases || Transferring phosphorus-containing groups |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.001514 | INHERITED FROM: Transferring one-carbon groups || Hydroxymethyl-, formyl- and related transferases || Glutamate formimidoyltransferase |
| Duplicated hybrid motif | 0.001626 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || phosphotransferase || Protein-N(pi)-phosphohistidine--D-glucose phosphotransferase || Transferring phosphorus-containing groups |
| Replicase NSP9 | 0.007238 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Coronavirus NSP10-like | 0.007238 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Coronavirus NSP8-like | 0.007238 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Coronavirus NSP7-like | 0.007238 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| YWTD domain | 0.0078 | INHERITED FROM: Protein-tyrosine kinases || Receptor protein-tyrosine kinase || Transferring phosphorus-containing groups |
| Ran binding protein zinc finger-like | 0.008813 | INHERITED FROM: Aminoacyltransferases || RBR-type E3 ubiquitin transferase || Acyltransferases |
| PX domain | 0.008915 | INHERITED FROM: Protein-serine/threonine kinases || Phosphatidylinositol-4-phosphate 3-kinase || Non-specific serine/threonine protein kinase || Transferring phosphorus-containing groups |
| HMG-box | 0.01027 | INHERITED FROM: Transferring one-carbon groups || [Histone H3]-lysine(4) N-trimethyltransferase || Methyltransferases |
| MFS general substrate transporter | 0.01027 | INHERITED FROM: Spermidine synthase || Transferring alkyl or aryl groups, other than methyl groups |
| CRAL/TRIO domain | 0.01081 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || Transferring phosphorus-containing groups |
| FabD/lysophospholipase-like | 0.01557 | INHERITED FROM: Fatty-acyl-CoA synthase system || Lovastatin nonaketide synthase || Fatty-acid synthase system || 10-deoxymethynolide syntase || Transferring groups other than amino-acyl groups || [Acyl-carrier-protein] S-malonyltransferase || [Acyl-carrier-protein] S-acetyltransferase || 2-methylbutanoate polyketide synthase || Beta-ketoacyl-[acyl-carrier-protein] synthase I || 6-deoxyerythronolide-B synthase || 6-methylsalicylic acid synthase || Acyltransferases || Narbonolide synthase |
| RNA-binding domain, RBD | 0.02208 | INHERITED FROM: Transferring one-carbon groups || [Histone H3]-lysine(4) N-trimethyltransferase || Polynucleotide adenylyltransferase || RNA uridylyltransferase || Methyltransferases || RING-type E3 ubiquitin transferase || tRNA (carboxymethyluridine(34)-5-O)-methyltransferase |
| SAP domain | 0.02264 | INHERITED FROM: NAD(+) ADP-ribosyltransferase || Aminoacyltransferases || Acyltransferases || RING-type E3 ubiquitin transferase |
| Galactose oxidase, central domain | 0.02773 | INHERITED FROM: Guanylate kinase || Transferring groups other than amino-acyl groups || Phosphotransferases with a phosphate group as acceptor || Transferring one-carbon groups || Acyltransferases || Methyltransferases || methoxycarbonyltransferase || tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase |
| GroEL apical domain-like | 0.02819 | INHERITED FROM: 1-phosphatidylinositol-3-phosphate 5-kinase || Phosphotransferases with an alcohol group as acceptor || Transferring phosphorus-containing groups |
| Outer arm dynein light chain 1 | 0.04089 | INHERITED FROM: Transferring alkyl or aryl groups, other than methyl groups || Protein geranylgeranyltransferase type II |
| ACT-like | 0.04103 | INHERITED FROM: Acetolactate synthase || Aspartate kinase || Phosphotransferases with a carboxy group as acceptor || Diphosphotransferases || GTP diphosphokinase || Transferring aldehyde or ketonic groups || Nucleotidyltransferases || [Protein-PII] uridylyltransferase || Transferring phosphorus-containing groups |
| NSP3A-like | 0.04984 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| SCP-like | 0.05086 | INHERITED FROM: Propanoyl-CoA C-acyltransferase || Transferring groups other than amino-acyl groups || Acyltransferases |
| Acid proteases | 0.06175 | INHERITED FROM: DNA-directed DNA polymerase || RNA-directed DNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| PA domain | 0.09218 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || RING-type E3 ubiquitin transferase |
| YrdC/RibB | 0.1047 | INHERITED FROM: L-threonylcarbamoyladenylate synthase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| DEATH domain | 0.1327 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase || Aminoacyltransferases || Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || Transferring phosphorus-containing groups || RING-type E3 ubiquitin transferase |
| SARS Nsp1-like | 0.1745 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases |
| Chaperone J-domain | 0.1858 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Tropomyosin | 0.1858 | INHERITED FROM: Acyltransferases |
| Cell wall binding repeat | 0.2196 | INHERITED FROM: Dextransucrase || Glycosyltransferases || Hexosyltransferases |
| Trypsin-like serine proteases | 0.2567 | INHERITED FROM: Methyltransferase cap1 || RNA-directed RNA polymerase || Nucleotidyltransferases || mRNA (guanine-N(7)-)-methyltransferase || Transferring phosphorus-containing groups |
| GTPase activation domain, GAP | 0.2678 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Formin homology 2 domain (FH2 domain) | 0.268 | INHERITED FROM: Aminoacyltransferases || RING-type E3 ubiquitin transferase |
| Quinoprotein alcohol dehydrogenase-like | 0.2769 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || Transferring phosphorus-containing groups |
| UBA-like | 0.314 | INHERITED FROM: Aminoacyltransferases || HECT-type E3 ubiquitin transferase || Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || Acyltransferases |
| Hedgehog/intein (Hint) domain | 0.3289 | INHERITED FROM: DNA-directed DNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Terpenoid synthases | 0.3415 | INHERITED FROM: (2E,6E)-farnesyl diphosphate synthase || All-trans-decaprenyl-diphosphate synthase || Transferring alkyl or aryl groups, other than methyl groups || Squalene synthase || 15-cis-phytoene synthase || specific) || Geranylgeranyl diphosphate synthase || Dimethylallyltranstransferase || All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) || Presqualene diphosphate synthase || 4,4'-diapophytoene synthase || Geranylfarnesyl diphosphate synthase |
| MIT domain | 0.3822 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || Transferring phosphorus-containing groups |
| MAPEG domain-like | 0.3831 | INHERITED FROM: Glutathione transferase || Transferring alkyl or aryl groups, other than methyl groups |
| C-terminal domain of transcriptional repressors | 0.4202 | INHERITED FROM: Pantothenate kinase || Phosphotransferases with an alcohol group as acceptor |
| C-type lectin-like | 0.5019 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| GroEL-intermediate domain like | 0.5388 | INHERITED FROM: 1-phosphatidylinositol-3-phosphate 5-kinase || Phosphotransferases with an alcohol group as acceptor |
| Homing endonucleases | 0.5486 | INHERITED FROM: DNA-directed DNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Multidrug efflux transporter AcrB transmembrane domain | 0.5783 | INHERITED FROM: Transferring alkyl or aryl groups, other than methyl groups || Heme o synthase |
| Concanavalin A-like lectins/glucanases | 0.5828 | INHERITED FROM: Xyloglucan:xyloglucosyl transferase || Aminoacyltransferases || Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || Acyltransferases || Glycosyltransferases || Hexosyltransferases || RING-type E3 ubiquitin transferase |
| HCP-like | 0.6764 | INHERITED FROM: [Elongation factor 2] kinase || Protein-serine/threonine kinases |
| Rubredoxin-like | 0.697 | INHERITED FROM: Adenylate kinase || Phosphotransferases with a phosphate group as acceptor |
| Carbon-nitrogen hydrolase | 0.7558 | INHERITED FROM: Transferring groups other than amino-acyl groups || Acyltransferases || Apolipoprotein N-acyltransferase |
| UROD/MetE-like | 0.8355 | INHERITED FROM: Transferring one-carbon groups || methyltransferase || 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase || Methyltransferases |
| Cobalamin (vitamin B12)-binding domain | 0.8528 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Methionine synthase |
| Tudor/PWWP/MBT | 0.9556 | INHERITED FROM: HECT-type E3 ubiquitin transferase || DNA (cytosine-5-)-methyltransferase |
| NTF2-like | 0.9767 | INHERITED FROM: Protein-serine/threonine kinases || Calcium/calmodulin-dependent protein kinase || Transferring phosphorus-containing groups |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: 23S rRNA (uracil(1939)-C(5))-methyltransferase || Polyribonucleotide nucleotidyltransferase || mRNA guanylyltransferase || Lysyltransferase || Nucleotidyltransferases |
| SAICAR synthase-like | 1 | INHERITED FROM: 1-phosphatidylinositol-3-phosphate 5-kinase || Inositol-hexakisphosphate kinase || Inositol-trisphosphate 3-kinase || Inositol-tetrakisphosphate 5-kinase || 1-phosphatidylinositol-4-phosphate 5-kinase || Phosphotransferases with an alcohol group as acceptor || Phosphatidylinositol-4,5-bisphosphate 3-kinase || 1-phosphatidylinositol-5-phosphate 4-kinase || Inositol-polyphosphate multikinase |
| Cysteine proteinases | 1 | INHERITED FROM: Glutathione gamma-glutamylcysteinyltransferase || Arylamine N-acetyltransferase || Aminoacyltransferases || RNA-directed RNA polymerase || Acyltransferases || Protein-glutamine gamma-glutamyltransferase |
| "Winged helix" DNA-binding domain | 1 | INHERITED FROM: 1-phosphatidylinositol-3-phosphate 5-kinase || Acetylserotonin O-methyltransferase || Flavone 3'-O-methyltransferase || 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase || Histone acetyltransferase || Isoflavone 4'-O-methyltransferase || (S)-scoulerine 9-O-methyltransferase || Caffeate O-methyltransferase || 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase || Isoflavone 7-O-methyltransferase || (RS)-norcoclaurine 6-O-methyltransferase || (Iso)eugenol O-methyltransferase || CTP-dependent riboflavin kinase || 6-hydroxytryprostatin B O-methyltransferase || Methyltransferases |
| Thioredoxin-like | 1 | INHERITED FROM: Glutathione transferase || Transferring alkyl or aryl groups, other than methyl groups || Protein-histidine kinases |
| Zn-dependent exopeptidases | 1 | INHERITED FROM: Glutaminyl-peptide cyclotransferase |
| (Phosphotyrosine protein) phosphatases II | 1 | INHERITED FROM: mRNA guanylyltransferase |
| Ribonuclease Rh-like | 1 | INHERITED FROM: RNA-directed RNA polymerase |
| Kringle-like | 1 | INHERITED FROM: Protein-tyrosine kinases || Receptor protein-tyrosine kinase |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | INHERITED FROM: Transaminases || Gamma-glutamyltransferase || Transferring nitrogenous groups || Amidophosphoribosyltransferase || Aminoacyltransferases || Glutamine--fructose-6-phosphate transaminase (isomerizing) |
| DNase I-like | 1 | INHERITED FROM: RNA-directed DNA polymerase |
| cAMP-binding domain-like | 1 | INHERITED FROM: cGMP-dependent protein kinase || Protein-serine/threonine kinases |
| ALDH-like | 1 | INHERITED FROM: Glutamate 5-kinase |
| RuvA domain 2-like | 1 | INHERITED FROM: Diadenylate cyclase |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Carboxy- and carbamoyltransferases || Aspartate carbamoyltransferase |
| vWA-like | 1 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || RING-type E3 ubiquitin transferase |
| Dihydropteroate synthetase-like | 1 | INHERITED FROM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase || Transferring alkyl or aryl groups, other than methyl groups || Transferring one-carbon groups || Diphosphotransferases || Dihydropteroate synthase || Co-methyltransferase || Tetrahydromethanopterin S-methyltransferase || Methyltransferases || Methionine synthase |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: Ethanol O-acetyltransferase || Homoserine O-succinyltransferase || Phospholipid:diacylglycerol acyltransferase || Homoserine O-acetyltransferase || Phosphatidylcholine--sterol O-acyltransferase || Fatty-acid synthase system || Bile acid-CoA:amino acid N-acyltransferase || Diacylglycerol O-acyltransferase || Transferring groups other than amino-acyl groups || Malonyl-[acyl-carrier protein] O-methyltransferase || Sinapoylglucose--sinapoylglucose O-sinapoyltransferase || [Acyl-carrier-protein] S-acetyltransferase || Trehalose O-mycolyltransferase || Acyltransferases |
| Terpenoid cyclases/Protein prenyltransferases | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than methyl groups || Protein farnesyltransferase || Protein geranylgeranyltransferase type I || Protein geranylgeranyltransferase type II |
| FMN-linked oxidoreductases | 1 | INHERITED FROM: Phosphoglycerol geranylgeranyltransferase || Transferring alkyl or aryl groups, other than methyl groups || [Acyl-carrier-protein] S-malonyltransferase || Heptaprenylglyceryl phosphate synthase |
| CBS-domain pair | 1 | INHERITED FROM: Homoserine O-acetyltransferase || Transferring groups other than amino-acyl groups |
| Lysozyme-like | 1 | INHERITED FROM: Peptidoglycan glycosyltransferase || Glycosyltransferases || Hexosyltransferases |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | INHERITED FROM: NAD(+) ADP-ribosyltransferase || Thymidine kinase || Phosphotransferases with an alcohol group as acceptor || Transferring phosphorus-containing groups |
| Nudix | 1 | INHERITED FROM: ADP-D-ribose pyrophosphorylase |
| Glycoside hydrolase/deacetylase | 1 | INHERITED FROM: Beta-galactoside alpha-(2,6)-sialyltransferase || Transferring other glycosyl groups |
| Inosine monophosphate dehydrogenase (IMPDH) | 1 | INHERITED FROM: Fatty-acyl-CoA synthase system || [Acyl-carrier-protein] S-malonyltransferase || [Acyl-carrier-protein] S-acetyltransferase |
| CheY-like | 1 | INHERITED FROM: Protein-histidine kinases || Transferring phosphorus-containing groups |
| Glutamine synthetase, N-terminal domain | 1 | INHERITED FROM: Protein S-acyltransferase |
| Prismane protein-like | 1 | INHERITED FROM: CO-methylating acetyl-CoA synthase |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase || Transferases for other substituted phosphate groups |
| Heme oxygenase-like | 1 | INHERITED FROM: Phosphooxymethylpyrimidine kinase || Hydroxymethylpyrimidine kinase |
| tRNA-binding arm | 1 | INHERITED FROM: glycyltransferase |
| Glutamine synthetase/guanido kinase | 1 | INHERITED FROM: Protein-arginine kinases || Arginine kinase || Creatine kinase || Protein S-acyltransferase || Phosphotransferases with a nitrogenous group as acceptor || Transferring phosphorus-containing groups |
| HIT-like | 1 | INHERITED FROM: ATP adenylyltransferase || Sulfate adenylyltransferase (ADP) || UDP-glucose--hexose-1-phosphate uridylyltransferase || Nucleotidyltransferases |
| HAD-like | 1 | INHERITED FROM: Alpha,alpha-trehalose-phosphate synthase (UDP-forming) || N-acylneuraminate cytidylyltransferase || Polynucleotide 5'-hydroxyl-kinase |
| FAD-linked oxidases, C-terminal domain | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than methyl groups || Alkylglycerone-phosphate synthase |
| Families 57/38 glycoside transferase middle domain | 1 | INHERITED FROM: 1,4-alpha-glucan branching enzyme || Hexosyltransferases |
| Ribonuclease H-like | 1 | INHERITED FROM: DNA-directed DNA polymerase || RNA-directed DNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Clavaminate synthase-like | 1 | INHERITED FROM: RNA-directed RNA polymerase || methoxycarbonyltransferase || tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase || tRNA (carboxymethyluridine(34)-5-O)-methyltransferase |
| Cytochrome c | 1 | INHERITED FROM: Transferring sulfur-containing groups || Thiosulfotransferases |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than methyl groups || Cysteate synthase || N-(2-amino-2-carboxyethyl)-L-glutamate synthase || Cysteine synthase |
| (Trans)glycosidases | 1 | INHERITED FROM: Dextransucrase || Starch synthase (maltosyl-transferring) || Sucrose phosphorylase || 4-alpha-glucanotransferase || Cyclomaltodextrin glucanotransferase || Glucosylglycerate phosphorylase || 1,4-alpha-glucan branching enzyme || Alpha-1,3-glucan synthase || Glycosyltransferases || Hexosyltransferases || Galactinol--sucrose galactosyltransferase |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | INHERITED FROM: Fatty-acyl-CoA synthase system || [Acyl-carrier-protein] S-malonyltransferase || [Acyl-carrier-protein] S-acetyltransferase |
| Adenine nucleotide alpha hydrolases-like | 1 | INHERITED FROM: tRNA-5-taurinomethyluridine 2-sulfurtransferase || tRNA-uridine 2-sulfurtransferase || FAD synthase || tRNA uracil 4-sulfurtransferase || Transferring sulfur-containing groups || Sulfurtransferases || Sulfate adenylyltransferase |
| Cyclophilin-like | 1 | INHERITED FROM: Aminoacyltransferases || RING-type E3 ubiquitin transferase |
| lambda repressor-like DNA-binding domains | 1 | INHERITED FROM: Ribosylnicotinamide kinase || Nicotinamide-nucleotide adenylyltransferase || DNA (cytosine-5-)-methyltransferase |
| BRCT domain | 1 | INHERITED FROM: NAD(+) ADP-ribosyltransferase || DNA nucleotidylexotransferase || RING-type E3 ubiquitin transferase |
| Kelch motif | 1 | INHERITED FROM: Transferring groups other than amino-acyl groups || Methyltransferases || methoxycarbonyltransferase || tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase |
| CYTH-like phosphatases | 1 | INHERITED FROM: mRNA guanylyltransferase || mRNA (guanine-N(7)-)-methyltransferase |
| Riboflavin synthase domain-like | 1 | INHERITED FROM: Riboflavin synthase |
| Globin-like | 1 | INHERITED FROM: Diguanylate cyclase |
| post-HMGL domain-like | 1 | INHERITED FROM: Acyl groups converted into alkyl groups on transfer || 2-isopropylmalate synthase || Acyltransferases |
| Phosphoglucomutase, C-terminal domain | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| FAD/NAD(P)-binding domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase || Cysteine-dependent adenosine diphosphate thiazole synthase || Transferring one-carbon groups || Pentosyltransferases || (NAD(P)H-oxidizing) || Methyltransferases || Sulfide-dependent adenosine diphosphate thiazole synthase |
| Nucleotidylyl transferase | 1 | INHERITED FROM: Ethanolamine-phosphate cytidylyltransferase || Choline-phosphate cytidylyltransferase || Nicotinamide-nucleotide adenylyltransferase || Nicotinate-nucleotide adenylyltransferase || Riboflavin kinase || D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase || Glycerol-3-phosphate cytidylyltransferase || D-glycero-beta-D-manno-heptose-7-phosphate kinase || FAD synthase || Pantetheine-phosphate adenylyltransferase || Nucleotidyltransferases || Transferring phosphorus-containing groups || Sulfate adenylyltransferase |
| SGNH hydrolase | 1 | INHERITED FROM: N-acylneuraminate cytidylyltransferase || Diglucosylglycerate octanoyltransferase |
| Macro domain-like | 1 | INHERITED FROM: Polynucleotide adenylyltransferase || RNA-directed RNA polymerase || Nucleotidyltransferases |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: Carboxy- and carbamoyltransferases || Aspartate carbamoyltransferase |
| Starch-binding domain-like | 1 | INHERITED FROM: Cyclomaltodextrin glucanotransferase || Glycosyltransferases || Hexosyltransferases |
| IpsF-like | 1 | INHERITED FROM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase |
| Galactose mutarotase-like | 1 | INHERITED FROM: Kojibiose phosphorylase || Hexosyltransferases |
| FAD-linked reductases, C-terminal domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase || Transferring one-carbon groups || Methyltransferases |
| Nicotinate/Quinolinate PRTase N-terminal domain-like | 1 | INHERITED FROM: Nicotinate-nucleotide diphosphorylase (carboxylating) || Pentosyltransferases || Glycosyltransferases |
| ADC synthase | 1 | INHERITED FROM: Transaminases || Transferring nitrogenous groups || Aminodeoxychorismate synthase |
| Class II aaRS and biotin synthetases | 1 | INHERITED FROM: Transferring groups other than amino-acyl groups || Lipoyl(octanoyl) transferase || Octanoyl-[GcvH]:protein N-octanoyltransferase || Lysyltransferase || Acyltransferases |
| PurM C-terminal domain-like | 1 | INHERITED FROM: Thiamine-phosphate kinase || Selenide, water dikinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase |
| Rudiment single hybrid motif | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
| Acetyl-CoA synthetase-like | 1 | INHERITED FROM: Transferring groups other than amino-acyl groups || Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase |
| PFL-like glycyl radical enzymes | 1 | INHERITED FROM: Transferring groups other than amino-acyl groups || Formate C-acetyltransferase |
| Sec63 N-terminal domain-like | 1 | INHERITED FROM: DNA-directed DNA polymerase |
| PreATP-grasp domain | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | INHERITED FROM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase || Diphosphotransferases || Dihydropteroate synthase |
| PDZ domain-like | 1 | INHERITED FROM: Aminoacyltransferases || Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || RING-type E3 ubiquitin transferase |
| Class I glutamine amidotransferase-like | 1 | INHERITED FROM: Homoserine O-succinyltransferase || Homoserine O-acetyltransferase || Transferring groups other than amino-acyl groups || 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase || Aminodeoxychorismate synthase || Acyltransferases |
| HD-domain/PDEase-like | 1 | INHERITED FROM: tRNA (cytidine(56)-2'-O)-methyltransferase || Diphosphotransferases || GTP diphosphokinase || Nucleotidyltransferases || [Protein-PII] uridylyltransferase || Transferring phosphorus-containing groups |
| P-loop containing nucleoside triphosphate hydrolases | 1 | INHERITED FROM: Adenylyl-sulfate kinase || 6-phosphofructo-2-kinase || Guanylate kinase || Adenylate dimethylallyltransferase (AMP-dependent) || Adenylate kinase || Ribosylnicotinamide kinase || Transferring alkyl or aryl groups, other than methyl groups || Uridine kinase || Methyltransferase cap1 || Shikimate kinase || Dephospho-CoA kinase || Thymidine kinase || Phosphotransferases with a phosphate group as acceptor || Tetraacyldisaccharide 4'-kinase || Polynucleotide 5'-hydroxyl-kinase || Polynucleotide adenylyltransferase || Phosphotransferases with an alcohol group as acceptor || Phosphate acetyltransferase || Nicotinate riboside kinase || RNA-directed RNA polymerase || tRNA dimethylallyltransferase || Sulfotransferases || [Pyruvate, phosphate dikinase] kinase || tRNA(Met) cytidine acetyltransferase || (d)CMP kinase || Adenosylcobinamide-phosphate guanylyltransferase || Phosphoribulokinase || dTMP kinase || mRNA (guanine-N(7)-)-methyltransferase || Gluconokinase || Transferring phosphorus-containing groups || Adenylate dimethylallyltransferase (ADP/ATP-dependent) || Sulfate adenylyltransferase |
| Nucleotide-binding domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase || Methyltransferases |
| NagB/RpiA/CoA transferase-like | 1 | INHERITED FROM: 3-oxoacid CoA-transferase || CoA-transferases || Transferring sulfur-containing groups |
| PurM N-terminal domain-like | 1 | INHERITED FROM: Thiamine-phosphate kinase || Selenide, water dikinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase |
| Dihydrofolate reductase-like | 1 | INHERITED FROM: Transferring one-carbon groups || Thymidylate synthase || Methyltransferases |
| Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| SIS domain | 1 | INHERITED FROM: Transaminases || Transferring nitrogenous groups || Glucokinase || Glutamine--fructose-6-phosphate transaminase (isomerizing) |
| beta-lactamase/transpeptidase-like | 1 | INHERITED FROM: Peptidoglycan glycosyltransferase || Glycosyltransferases || Hexosyltransferases |
| Phosphoglycerate mutase-like | 1 | INHERITED FROM: 6-phosphofructo-2-kinase || Inositol-hexakisphosphate kinase || Diphosphoinositol-pentakisphosphate kinase |
| RmlC-like cupins | 1 | INHERITED FROM: Guanosine phosphorylase || Pyrimidine-nucleoside phosphorylase || Uridine phosphorylase || Mannose-1-phosphate guanylyltransferase || Thymidine phosphorylase || Pentosyltransferases || Glycosyltransferases |
| SCOP hierarchy in SUPERFAMILY | 1 | INHERITED FROM: cAMP-dependent protein kinase || 3-deoxy-7-phosphoheptulonate synthase || Protein-serine/threonine kinases || Nicotinamide phosphoribosyltransferase |
| ADC-like | 1 | INHERITED FROM: AMP phosphorylase |
| Pentein | 1 | INHERITED FROM: Amidinotransferases |
| Zinc beta-ribbon | 1 | INHERITED FROM: Histone acetyltransferase || DNA-directed RNA polymerase |
| Translation proteins | 1 | INHERITED FROM: Adenylyl-sulfate kinase || Nucleotidyltransferases || Sulfate adenylyltransferase |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: mRNA guanylyltransferase || mRNA (guanine-N(7)-)-methyltransferase |
| Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: Inositol-hexakisphosphate kinase || Inositol-tetrakisphosphate 1-kinase || ATP citrate synthase || Phosphotransferases with paired acceptors || Inositol-1,3,4-trisphosphate 5/6-kinase || Pyruvate, water dikinase || Pyruvate, phosphate dikinase || Diphosphoinositol-pentakisphosphate kinase || Phosphoribosylglycinamide formyltransferase |
| Dimeric alpha+beta barrel | 1 | INHERITED FROM: Acyl groups converted into alkyl groups on transfer || Homocitrate synthase |
| TGS-like | 1 | INHERITED FROM: Diphosphotransferases || GTP diphosphokinase |
| Arabinanase/levansucrase/invertase | 1 | INHERITED FROM: Levansucrase || Glycosyltransferases || Hexosyltransferases |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Fatty-acyl-CoA synthase system || Lovastatin nonaketide synthase || Fatty-acid synthase system || 10-deoxymethynolide syntase || Shikimate kinase || ATP citrate synthase || UDP-4-amino-4-deoxy-L-arabinose formyltransferase || Aspartate kinase || [Acyl-carrier-protein] S-acetyltransferase || 2-methylbutanoate polyketide synthase || Beta-ketoacyl-[acyl-carrier-protein] synthase I || Uroporphyrinogen-III C-methyltransferase || 6-deoxyerythronolide-B synthase || 3-phosphoshikimate 1-carboxyvinyltransferase || 6-methylsalicylic acid synthase || Narbonolide synthase |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 1 | INHERITED FROM: Nicotinate-nucleotide diphosphorylase (carboxylating) || Pentosyltransferases || Nicotinamide phosphoribosyltransferase || Glycosyltransferases |
| Succinyl-CoA synthetase domains | 1 | INHERITED FROM: ATP citrate synthase || Acyl groups converted into alkyl groups on transfer |
| MesJ substrate recognition domain-like | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
| Six-hairpin glycosidases | 1 | INHERITED FROM: Kojibiose phosphorylase || 4-alpha-glucanotransferase || Hexosyltransferases |
| dUTPase-like | 1 | INHERITED FROM: DNA-directed DNA polymerase || RNA-directed DNA polymerase |
| Galactose-binding domain-like | 1 | INHERITED FROM: Protein-tyrosine kinases || HECT-type E3 ubiquitin transferase || Receptor protein-tyrosine kinase |
| Dehydroquinate synthase-like | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than methyl groups || Shikimate kinase || Phosphotransferases with an alcohol group as acceptor || 3-phosphoshikimate 1-carboxyvinyltransferase |
| GroES-like | 1 | INHERITED FROM: Fatty-acid synthase system || [Acyl-carrier-protein] S-malonyltransferase || [Acyl-carrier-protein] S-acetyltransferase || 2-methylbutanoate polyketide synthase || Beta-ketoacyl-[acyl-carrier-protein] synthase I |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | INHERITED FROM: tRNA (guanine(37)-N(1))-methyltransferase || 6-phosphofructokinase |
| FAD-binding/transporter-associated domain-like | 1 | INHERITED FROM: Alkylglycerone-phosphate synthase |
| PheT/TilS domain | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
| Nucleotide cyclase | 1 | INHERITED FROM: Diguanylate cyclase || Nucleotidyltransferases |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Phosphohistidine domain | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| HPr-like | 0 | Direct |
| CoA-transferase family III (CaiB/BaiF) | 0 | Direct |
| LanC-like | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| QueA-like | 0 | Direct |
| Pyridoxine 5'-phosphate synthase | 0 | Direct |
| PUA domain-like | 0 | Direct |
| NusB-like | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| tRNA-guanine transglycosylase | 0 | Direct |
| Prenyltransferase-like | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Retrovirus capsid dimerization domain-like | 0 | Direct |
| Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
| KA1-like | 0 | Direct |
| Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | Direct |
| ApbE-like | 0 | Direct |
| Malate synthase G | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| L domain-like | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | Direct |
| OMPA-like | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
| GlnB-like | 0 | Direct |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
| DNA polymerase III chi subunit | 0 | Direct |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| HAMP domain-like | 0 | Direct |
| PilZ domain-like | 0 | Direct |
| CheW-like | 0 | Direct |
| Putative methyltransferase TM0872, insert domain | 0 | Direct |
| ARM repeat | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| SH3-domain | 0 | Direct |
| Methyl-coenzyme M reductase subunits | 0 | Direct |
| PPK N-terminal domain-like | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Pentapeptide repeat-like | 0 | Direct |
| Riboflavin kinase-like | 0 | Direct |
| Methionine synthase activation domain-like | 0 | Direct |
| TAF(II)230 TBP-binding fragment | 0 | Direct |
| EndoU-like | 0 | Direct |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | Direct |
| NadA-like | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Retroviral matrix proteins | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
| DAK1/DegV-like | 0 | Direct |
| PK C-terminal domain-like | 0 | Direct |
| MIR domain | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| alpha-D-mannose-specific plant lectins | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| Glycerate kinase I | 0 | Direct |
| MoeA N-terminal region -like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| ThiG-like | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| Pre-PUA domain | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
| Methionine synthase domain | 0 | Direct |
| BAR/IMD domain-like | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| TTHA0583/YokD-like | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| Molybdopterin synthase subunit MoaE | 0 | Direct |
| ClpS-like | 0 | Direct |
| YgbK-like | 0 | Direct |
| Thiolase-like | 0 | Direct |
| RNA polymerase subunits | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| DmpA/ArgJ-like | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| Ankyrin repeat | 0 | Direct |
| PTS system fructose IIA component-like | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| Trimerization domain of TRAF | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| E set domains | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Monomethylamine methyltransferase MtmB | 0 | Direct |
| Polo-box domain | 0 | Direct |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| Sporulation response regulatory protein Spo0B | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| SET domain | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| TAZ domain | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Tetrapyrrole methylase | 0 | Direct |
| PRTase-like | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| CCHHC domain | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| RNA polymerase subunit RPB10 | 0 | Direct |
| RPB5-like RNA polymerase subunit | 0 | Direct |
| MoeA C-terminal domain-like | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| PsbU/PolX domain-like | 0 | Direct |
| PTS IIb component | 0 | Direct |
| PLP-dependent transferases | 0 | Direct |
| NRDP1 C-terminal domain-like | 0 | Direct |
| Aldolase | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| Thymidylate synthase-complementing protein Thy1 | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| WGR domain-like | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| PHP domain-like | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | Direct |
| Zinc hairpin stack | 0 | Direct |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Immunoglobulin | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0 | Direct |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | Direct |
| Cobalamin adenosyltransferase-like | 0 | Direct |
| Formyltransferase | 0 | Direct |
| Insert subdomain of RNA polymerase alpha subunit | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| PHP14-like | 0 | Direct |
| Lumazine synthase | 0 | Direct |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | Direct |
| SH2 domain | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 0 | Direct |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
| UBC-like | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Leucine zipper domain | 0 | Direct |
| Sema domain | 0 | Direct |
| Glucose permease domain IIB | 0 | Direct |
| Cyclin-like | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
| Phosphoglycerate kinase | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| CheY-binding domain of CheA | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| L27 domain | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| Notch domain | 0 | Direct |
| SSo0622-like | 0 | Direct |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| Siroheme synthase middle domains-like | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| Trm112p-like | 0 | Direct |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
| Thiamin pyrophosphokinase, catalytic domain | 0 | Direct |
| PTS system IIB component-like | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | Direct |
| AF1531-like | 0 | Direct |
| Poly(A) polymerase catalytic subunit-like | 0 | Direct |
| RING/U-box | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| CofD-like | 0 | Direct |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | Direct |
| FAT domain of focal adhesion kinase | 0 | Direct |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | Direct |
| YojJ-like | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| Protein kinase-like (PK-like) | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| Docking domain B of the erythromycin polyketide synthase (DEBS) | 0 | Direct |
| SAM/Pointed domain | 0 | Direct |
| C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
| Aspartate/ornithine carbamoyltransferase | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| WWE domain | 0 | Direct |
| Thiamin phosphate synthase | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| Carbamate kinase-like | 0 | Direct |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | Direct |
| CbiD-like | 0 | Direct |
| CHY zinc finger-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | Direct |
| RPB6/omega subunit-like | 0 | Direct |
| AFP III-like domain | 0 | Direct |
| Poly A polymerase C-terminal region-like | 0 | Direct |
| DhaL-like | 0 | Direct |
| PH domain-like | 0.00000000000000277 | Direct |
| Fic-like | 0.000000000000006994 | Direct |
| Sensory domain-like | 0.00000000000004896 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0.0000000000001514 | Direct |
| TRAF domain-like | 0.0000000000005217 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0.0000000000006668 | Direct |
| Molybdenum cofactor biosynthesis proteins | 0.0000000000006732 | Direct |
| RNI-like | 0.000000000001847 | Direct |
| FYVE/PHD zinc finger | 0.000000000009672 | Direct |
| Bromodomain | 0.00000000001264 | Direct |
| beta-beta-alpha zinc fingers | 0.00000000001664 | Direct |
| L30e-like | 0.00000000003133 | Direct |
| CCCH zinc finger | 0.00000000007581 | Direct |
| Homeodomain-like | 0.0000000001152 | Direct |
| Ricin B-like lectins | 0.0000000005723 | Direct |
| ClpP/crotonase | 0.0000000007921 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0.000000002565 | Direct |
| Phospholipase D/nuclease | 0.000000005204 | Direct |
| WW domain | 0.000000005545 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0.0000001122 | Direct |
| Single hybrid motif | 0.0000001684 | Direct |
| HprK N-terminal domain-like | 0.0000001793 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.0000002019 | Direct |
| Chromo domain-like | 0.0000009356 | Direct |
| post-AAA+ oligomerization domain-like | 0.000001016 | Direct |
| Ubiquitin-like | 0.000002716 | Direct |
| WD40 repeat-like | 0.000007361 | Direct |
| NHL repeat | 0.00001305 | Direct |
| PIN domain-like | 0.00001868 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.00006736 | Direct |
| Second domain of FERM | 0.00008173 | Direct |
| GckA/TtuD-like | 0.0001011 | Direct |
| Glycosyl hydrolase domain | 0.0001532 | Direct |
| ACP-like | 0.0001549 | Direct |
| TPR-like | 0.0002792 | Direct |
| SMAD/FHA domain | 0.0002936 | Direct |
| GAF domain-like | 0.0004318 | Direct |
| EF-hand | 0.0006043 | Direct |
| N-(deoxy)ribosyltransferase-like | 0.001014 | Inherited |
| beta-sandwich domain of Sec23/24 | 0.001231 | Inherited |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.001514 | Inherited |
| Duplicated hybrid motif | 0.001626 | Inherited |
| Replicase NSP9 | 0.007238 | Inherited |
| Coronavirus NSP10-like | 0.007238 | Inherited |
| Coronavirus NSP8-like | 0.007238 | Inherited |
| Coronavirus NSP7-like | 0.007238 | Inherited |
| YWTD domain | 0.0078 | Inherited |
| Ran binding protein zinc finger-like | 0.008813 | Inherited |
| PX domain | 0.008915 | Inherited |
| HMG-box | 0.01027 | Inherited |
| MFS general substrate transporter | 0.01027 | Inherited |
| CRAL/TRIO domain | 0.01081 | Inherited |
| FabD/lysophospholipase-like | 0.01557 | Inherited |
| RNA-binding domain, RBD | 0.02208 | Inherited |
| SAP domain | 0.02264 | Inherited |
| Galactose oxidase, central domain | 0.02773 | Inherited |
| GroEL apical domain-like | 0.02819 | Inherited |
| Outer arm dynein light chain 1 | 0.04089 | Inherited |
| ACT-like | 0.04103 | Inherited |
| NSP3A-like | 0.04984 | Inherited |
| SCP-like | 0.05086 | Inherited |
| Acid proteases | 0.06175 | Inherited |
| PA domain | 0.09218 | Inherited |
| YrdC/RibB | 0.1047 | Inherited |
| DEATH domain | 0.1327 | Inherited |
| SARS Nsp1-like | 0.1745 | Inherited |
| Chaperone J-domain | 0.1858 | Inherited |
| Tropomyosin | 0.1858 | Inherited |
| Cell wall binding repeat | 0.2196 | Inherited |
| Trypsin-like serine proteases | 0.2567 | Inherited |
| GTPase activation domain, GAP | 0.2678 | Inherited |
| Formin homology 2 domain (FH2 domain) | 0.268 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.2769 | Inherited |
| UBA-like | 0.314 | Inherited |
| Hedgehog/intein (Hint) domain | 0.3289 | Inherited |
| Terpenoid synthases | 0.3415 | Inherited |
| MIT domain | 0.3822 | Inherited |
| MAPEG domain-like | 0.3831 | Inherited |
| C-terminal domain of transcriptional repressors | 0.4202 | Inherited |
| C-type lectin-like | 0.5019 | Inherited |
| GroEL-intermediate domain like | 0.5388 | Inherited |
| Homing endonucleases | 0.5486 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.5783 | Inherited |
| Concanavalin A-like lectins/glucanases | 0.5828 | Inherited |
| HCP-like | 0.6764 | Inherited |
| Rubredoxin-like | 0.697 | Inherited |
| Carbon-nitrogen hydrolase | 0.7558 | Inherited |
| UROD/MetE-like | 0.8355 | Inherited |
| Cobalamin (vitamin B12)-binding domain | 0.8528 | Inherited |
| Tudor/PWWP/MBT | 0.9556 | Inherited |
| NTF2-like | 0.9767 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
| SAICAR synthase-like | 1 | Inherited |
| Cysteine proteinases | 1 | Inherited |
| "Winged helix" DNA-binding domain | 1 | Inherited |
| Thioredoxin-like | 1 | Inherited |
| Zn-dependent exopeptidases | 1 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 1 | Inherited |
| Ribonuclease Rh-like | 1 | Inherited |
| Kringle-like | 1 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | Inherited |
| DNase I-like | 1 | Inherited |
| cAMP-binding domain-like | 1 | Inherited |
| ALDH-like | 1 | Inherited |
| RuvA domain 2-like | 1 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| vWA-like | 1 | Inherited |
| Dihydropteroate synthetase-like | 1 | Inherited |
| alpha/beta-Hydrolases | 1 | Inherited |
| Terpenoid cyclases/Protein prenyltransferases | 1 | Inherited |
| FMN-linked oxidoreductases | 1 | Inherited |
| CBS-domain pair | 1 | Inherited |
| Lysozyme-like | 1 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | Inherited |
| Nudix | 1 | Inherited |
| Glycoside hydrolase/deacetylase | 1 | Inherited |
| Inosine monophosphate dehydrogenase (IMPDH) | 1 | Inherited |
| CheY-like | 1 | Inherited |
| Glutamine synthetase, N-terminal domain | 1 | Inherited |
| Prismane protein-like | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| Heme oxygenase-like | 1 | Inherited |
| tRNA-binding arm | 1 | Inherited |
| Glutamine synthetase/guanido kinase | 1 | Inherited |
| HIT-like | 1 | Inherited |
| HAD-like | 1 | Inherited |
| FAD-linked oxidases, C-terminal domain | 1 | Inherited |
| Families 57/38 glycoside transferase middle domain | 1 | Inherited |
| Ribonuclease H-like | 1 | Inherited |
| Clavaminate synthase-like | 1 | Inherited |
| Cytochrome c | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| (Trans)glycosidases | 1 | Inherited |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | Inherited |
| Adenine nucleotide alpha hydrolases-like | 1 | Inherited |
| Cyclophilin-like | 1 | Inherited |
| lambda repressor-like DNA-binding domains | 1 | Inherited |
| BRCT domain | 1 | Inherited |
| Kelch motif | 1 | Inherited |
| CYTH-like phosphatases | 1 | Inherited |
| Riboflavin synthase domain-like | 1 | Inherited |
| Globin-like | 1 | Inherited |
| post-HMGL domain-like | 1 | Inherited |
| Phosphoglucomutase, C-terminal domain | 1 | Inherited |
| FAD/NAD(P)-binding domain | 1 | Inherited |
| Nucleotidylyl transferase | 1 | Inherited |
| SGNH hydrolase | 1 | Inherited |
| Macro domain-like | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
| Starch-binding domain-like | 1 | Inherited |
| IpsF-like | 1 | Inherited |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Galactose mutarotase-like | 1 | Inherited |
| FAD-linked reductases, C-terminal domain | 1 | Inherited |
| Nicotinate/Quinolinate PRTase N-terminal domain-like | 1 | Inherited |
| ADC synthase | 1 | Inherited |
| Class II aaRS and biotin synthetases | 1 | Inherited |
| PurM C-terminal domain-like | 1 | Inherited |
| Rudiment single hybrid motif | 1 | Inherited |
| Acetyl-CoA synthetase-like | 1 | Inherited |
| PFL-like glycyl radical enzymes | 1 | Inherited |
| Sec63 N-terminal domain-like | 1 | Inherited |
| PreATP-grasp domain | 1 | Inherited |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | Inherited |
| PDZ domain-like | 1 | Inherited |
| Class I glutamine amidotransferase-like | 1 | Inherited |
| HD-domain/PDEase-like | 1 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 1 | Inherited |
| Nucleotide-binding domain | 1 | Inherited |
| NagB/RpiA/CoA transferase-like | 1 | Inherited |
| PurM N-terminal domain-like | 1 | Inherited |
| Dihydrofolate reductase-like | 1 | Inherited |
| Phosphoglucomutase, first 3 domains | 1 | Inherited |
| SIS domain | 1 | Inherited |
| beta-lactamase/transpeptidase-like | 1 | Inherited |
| Phosphoglycerate mutase-like | 1 | Inherited |
| RmlC-like cupins | 1 | Inherited |
| SCOP hierarchy in SUPERFAMILY | 1 | Inherited |
| ADC-like | 1 | Inherited |
| Pentein | 1 | Inherited |
| Zinc beta-ribbon | 1 | Inherited |
| Translation proteins | 1 | Inherited |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
| Dimeric alpha+beta barrel | 1 | Inherited |
| TGS-like | 1 | Inherited |
| Arabinanase/levansucrase/invertase | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 1 | Inherited |
| Succinyl-CoA synthetase domains | 1 | Inherited |
| MesJ substrate recognition domain-like | 1 | Inherited |
| Six-hairpin glycosidases | 1 | Inherited |
| dUTPase-like | 1 | Inherited |
| Galactose-binding domain-like | 1 | Inherited |
| Dehydroquinate synthase-like | 1 | Inherited |
| GroES-like | 1 | Inherited |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | Inherited |
| FAD-binding/transporter-associated domain-like | 1 | Inherited |
| PheT/TilS domain | 1 | Inherited |
| Nucleotide cyclase | 1 | Inherited |
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Family(show details)
Family domains annotated to this EC term (SDEC level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| alpha-D-mannose-specific plant lectins | 0 | DIRECT |
| Guanidinoacetate methyltransferase | 0 | DIRECT |
| Glycogenin | 0 | DIRECT |
| Galactoside acetyltransferase-like | 0 | DIRECT |
| hypothetical RNA methyltransferase | 0 | DIRECT |
| Archaeal tRNA CCA-adding enzyme | 0 | DIRECT |
| Chemotaxis receptor methyltransferase CheR, C-terminal domain | 0 | DIRECT |
| YhiQ-like | 0 | DIRECT |
| BphP N-terminal domain-like | 0 | DIRECT |
| HTLV-II matrix protein | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| TK-like Pyr module | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| KaiB-like | 0 | DIRECT |
| CofD-like | 0 | DIRECT |
| mRNA cap (Guanine N-7) methyltransferase | 0 | DIRECT |
| Leucine zipper domain | 0 | DIRECT |
| RNA polymerase omega subunit | 0 | DIRECT |
| Trimerization domain of TRAF | 0 | DIRECT |
| AD-003 protein-like | 0 | DIRECT |
| Glutathione S-transferase (GST), C-terminal domain | 0 | DIRECT |
| Glutaminyl-peptide cyclotransferase-like | 0 | DIRECT |
| Thiamin pyrophosphokinase, catalytic domain | 0 | DIRECT |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| DNA polymerase beta-like, second domain | 0 | DIRECT |
| PTS system, Fructose specific IIB subunit-like | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| GrpB-like | 0 | DIRECT |
| YgbK-like | 0 | DIRECT |
| CoaX-like | 0 | DIRECT |
| Polygalacturonase inhibiting protein PGIP | 0 | DIRECT |
| T7 RNA polymerase | 0 | DIRECT |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| DhaL-like | 0 | DIRECT |
| ArgJ-like | 0 | DIRECT |
| N-acetylglucosaminyltransferase I | 0 | DIRECT |
| Methyl-coenzyme M reductase alpha and beta chain N-terminal domain | 0 | DIRECT |
| UBC-related | 0 | DIRECT |
| RIO1-like kinases | 0 | DIRECT |
| Fumble-like | 0 | DIRECT |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | DIRECT |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | DIRECT |
| Glycosyl transferases group 1 | 0 | DIRECT |
| PAPS sulfotransferase | 0 | DIRECT |
| Glucose-inhibited division protein B (GidB) | 0 | DIRECT |
| N-6 DNA Methylase-like | 0 | DIRECT |
| PPK middle domain-like | 0 | DIRECT |
| ThiG-like | 0 | DIRECT |
| Plant O-methyltransferase, N-terminal domain | 0 | DIRECT |
| PTS IIb component | 0 | DIRECT |
| Viral proteases | 0 | DIRECT |
| AF1531-like | 0 | DIRECT |
| SPRY domain | 0 | DIRECT |
| PyrH-like | 0 | DIRECT |
| Ssp2 C-terminal domain-like | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Protein kinases, catalytic subunit | 0 | DIRECT |
| ADP-specific Phosphofructokinase/Glucokinase | 0 | DIRECT |
| Receiver domain of the ethylene receptor | 0 | DIRECT |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | DIRECT |
| Sensory domain of two-component sensor kinase | 0 | DIRECT |
| YhhF-like | 0 | DIRECT |
| Amidinotransferase | 0 | DIRECT |
| Plant O-methyltransferase, C-terminal domain | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| Phytochelatin synthase | 0 | DIRECT |
| Thi4-like | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| RWD domain | 0 | DIRECT |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
| Viral cysteine protease of trypsin fold | 0 | DIRECT |
| TrmB-like | 0 | DIRECT |
| Chemotaxis protein CheA P1 domain | 0 | DIRECT |
| TRM1-like | 0 | DIRECT |
| Pyruvate phosphate dikinase, N-terminal domain | 0 | DIRECT |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
| Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
| CoA-transferase family III (CaiB/BaiF) | 0 | DIRECT |
| FCH domain | 0 | DIRECT |
| Ribonuclease PH domain 1-like | 0 | DIRECT |
| ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain | 0 | DIRECT |
| RmsB N-terminal domain-like | 0 | DIRECT |
| TK-like PP module | 0 | DIRECT |
| Transcriptional factor domain | 0 | DIRECT |
| Molybdopterin synthase subunit MoaE | 0 | DIRECT |
| Mib/herc2 domain | 0 | DIRECT |
| Malate synthase G | 0 | DIRECT |
| L domain | 0 | DIRECT |
| Archaeal tRNA CCA-adding enzyme substrate-binding domain | 0 | DIRECT |
| PB1 domain | 0 | DIRECT |
| Thiolase-related | 0 | DIRECT |
| tRNA(1-methyladenosine) methyltransferase-like | 0 | DIRECT |
| Phosphomethylpyrimidine kinase C-terminal domain-like | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| ROK | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| Archaeal tRNA CCA-adding enzyme catalytic domain | 0 | DIRECT |
| IIA domain of mannitol-specific and ntr phosphotransferase EII | 0 | DIRECT |
| AF0751-like | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| Sporulation response regulatory protein Spo0B | 0 | DIRECT |
| Glycine N-methyltransferase | 0 | DIRECT |
| HAMP domain | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| RpiR-like | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Shikimate kinase (AroK) | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| PBP transglycosylase domain-like | 0 | DIRECT |
| E-set domains of sugar-utilizing enzymes | 0 | DIRECT |
| Riboflavin synthase | 0 | DIRECT |
| NOL1/NOP2/sun | 0 | DIRECT |
| 4'-Phosphopantetheinyl transferase SFP | 0 | DIRECT |
| Adenylyltransferase | 0 | DIRECT |
| MoeA N-terminal region -like | 0 | DIRECT |
| Salicylic acid carboxyl methyltransferase (SAMT) | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| HMGL-like | 0 | DIRECT |
| Multidomain sulfurtransferase (rhodanese) | 0 | DIRECT |
| DNA polymerase III chi subunit | 0 | DIRECT |
| Adenosine-5'phosphosulfate kinase (APS kinase) | 0 | DIRECT |
| RPB6 | 0 | DIRECT |
| CTP-dependent riboflavin kinase-like | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| FMDV leader protease | 0 | DIRECT |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | DIRECT |
| Histone lysine methyltransferases | 0 | DIRECT |
| Methicillin resistance protein FemA probable tRNA-binding arm | 0 | DIRECT |
| Filamin repeat (rod domain) | 0 | DIRECT |
| 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase IspE | 0 | DIRECT |
| Insert subdomain of RNA polymerase alpha subunit | 0 | DIRECT |
| YbeA-like | 0 | DIRECT |
| BRCT domain | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
| RNA helicase | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| Classic zinc finger, C2H2 | 0 | DIRECT |
| UDPGT-like | 0 | DIRECT |
| Trehalose-6-phosphate synthase, OtsA | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| rRNA adenine dimethylase-like | 0 | DIRECT |
| Outer membrane enzyme PagP | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| Transcription factor IIB (TFIIB), core domain | 0 | DIRECT |
| MoeA C-terminal domain-like | 0 | DIRECT |
| Type II thymidine kinase | 0 | DIRECT |
| THUMP domain | 0 | DIRECT |
| Glucokinase | 0 | DIRECT |
| SepSecS-like | 0 | DIRECT |
| Swapped Polo-box domain | 0 | DIRECT |
| ThiI-like | 0 | DIRECT |
| RNA methyltransferase FtsJ | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| DNA polymerase beta-like | 0 | DIRECT |
| GlmU C-terminal domain-like | 0 | DIRECT |
| FucT-like | 0 | DIRECT |
| Ketopantoate hydroxymethyltransferase PanB | 0 | DIRECT |
| Type II DNA methylase | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | DIRECT |
| Pyruvate oxidase and decarboxylase PP module | 0 | DIRECT |
| Gluconate kinase | 0 | DIRECT |
| Thiopurine S-methyltransferase | 0 | DIRECT |
| ATP sulfurylase catalytic domain | 0 | DIRECT |
| Glucose permease domain IIB | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Cobalamin adenosyltransferase | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| Nsp15 N-terminal domain-like | 0 | DIRECT |
| Thymidylate synthase-complementing protein Thy1 | 0 | DIRECT |
| Retrovirus capsid protein C-terminal domain | 0 | DIRECT |
| AAT-like | 0 | DIRECT |
| FAT domain of focal adhesion kinase | 0 | DIRECT |
| APC10-like | 0 | DIRECT |
| PWWP domain | 0 | DIRECT |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| CbiD-like | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| Cold shock DNA-binding domain-like | 0 | DIRECT |
| Calmodulin-like | 0 | DIRECT |
| MarR-like transcriptional regulators | 0 | DIRECT |
| Legume lectins | 0 | DIRECT |
| Post formyltransferase domain | 0 | DIRECT |
| Hypothetical protein MJ0882 | 0 | DIRECT |
| Leucine carboxy methyltransferase Ppm1 | 0 | DIRECT |
| Glycerol kinase | 0 | DIRECT |
| Protein-L-isoaspartyl O-methyltransferase | 0 | DIRECT |
| CPH domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Chalcone synthase-like | 0 | DIRECT |
| Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain | 0 | DIRECT |
| Peptidoglycan biosynthesis glycosyltransferase MurG | 0 | DIRECT |
| CAT-like | 0 | DIRECT |
| beta-lactamase inhibitor protein-II, BLIP-II | 0 | DIRECT |
| AF1056-like | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| RNA polymerase subunit RPB10 | 0 | DIRECT |
| QueA-like | 0 | DIRECT |
| Monomethylamine methyltransferase MtmB | 0 | DIRECT |
| Chromo barrel domain | 0 | DIRECT |
| Siroheme synthase middle domains-like | 0 | DIRECT |
| Archaeosine tRNA-guanine transglycosylase, C2 domain | 0 | DIRECT |
| AFP III-like domain | 0 | DIRECT |
| Molybdenum cofactor biosynthesis protein MobA | 0 | DIRECT |
| Phosphate binding protein-like | 0 | DIRECT |
| Methionine synthase SAM-binding domain | 0 | DIRECT |
| Exostosin | 0 | DIRECT |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | DIRECT |
| Mycobacterial antigens | 0 | DIRECT |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | DIRECT |
| Cobalamin-independent methionine synthase | 0 | DIRECT |
| I set domains | 0 | DIRECT |
| Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
| Variant RING domain | 0 | DIRECT |
| Homeodomain | 0 | DIRECT |
| Zinc hairpin stack | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| Molybdenum cofactor biosynthesis protein MoeB | 0 | DIRECT |
| YeaZ-like | 0 | DIRECT |
| RBP11/RpoL | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| Met-10+ protein-like | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| COMT-like | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| NadA-like | 0 | DIRECT |
| N6 adenine-specific DNA methylase, DAM | 0 | DIRECT |
| (Uracil-5-)-methyltransferase | 0 | DIRECT |
| Pyridoxine 5'-phosphate synthase | 0 | DIRECT |
| Squalene synthase | 0 | DIRECT |
| V set domains (antibody variable domain-like) | 0 | DIRECT |
| mRNA capping enzyme | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| Pentapeptide repeats | 0 | DIRECT |
| FabD-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| O-acetyltransferase | 0 | DIRECT |
| Protein prenyltransferases | 0 | DIRECT |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | DIRECT |
| Immunodeficiency virus matrix proteins | 0 | DIRECT |
| Pyruvate phosphate dikinase, C-terminal domain | 0 | DIRECT |
| DAK1 | 0 | DIRECT |
| Single-domain sulfurtransferase | 0 | DIRECT |
| Caliciviridae-like VP | 0 | DIRECT |
| FemXAB nonribosomal peptidyltransferases | 0 | DIRECT |
| Cytidylytransferase | 0 | DIRECT |
| Histamine methyltransferase | 0 | DIRECT |
| Ankyrin repeat | 0 | DIRECT |
| Polyphosphate kinase C-terminal domain | 0 | DIRECT |
| Phosphoglycerate kinase | 0 | DIRECT |
| Nsp15 C-terminal domain-like | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| Mycolic acid cyclopropane synthase | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| MHCK/EF2 kinase | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| Docking domain B of the erythromycin polyketide synthase (DEBS) | 0 | DIRECT |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | DIRECT |
| Enolpyruvate transferase, EPT | 0 | DIRECT |
| Trm112p-like | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Phosphoribosyltransferases (PRTases) | 0 | DIRECT |
| Glycerate kinase I | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| PTS system, Lactose/Cellobiose specific IIB subunit | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| N5-glutamine methyltransferase, HemK | 0 | DIRECT |
| YojJ-like | 0 | DIRECT |
| Pyruvate kinase beta-barrel domain | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| Methyl-coenzyme M reductase gamma chain | 0 | DIRECT |
| ATP sulfurylase N-terminal domain | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | DIRECT |
| AmyC C-terminal domain-like | 0 | DIRECT |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | DIRECT |
| mannose-1-phosphate guanylyl transferase | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | DIRECT |
| Nucleotide and nucleoside kinases | 0 | DIRECT |
| Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
| Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | DIRECT |
| Autoinducer synthetase | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Deoxyhypusine synthase, DHS | 0 | DIRECT |
| 1,3-glucuronyltransferase | 0 | DIRECT |
| Prenyltransferase-like | 0 | DIRECT |
| Aminoglycoside 3-N-acetyltransferase-like | 0 | DIRECT |
| Lumazine synthase | 0 | DIRECT |
| N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system | 0 | DIRECT |
| GAG polyprotein M-domain | 0 | DIRECT |
| Phosphoribulokinase/pantothenate kinase | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| RPB5 | 0 | DIRECT |
| Phytochrome-specific domain | 0 | DIRECT |
| CHY zinc finger | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | DIRECT |
| GABA-aminotransferase-like | 0 | DIRECT |
| Retroviral integrase, catalytic domain | 0 | DIRECT |
| U-box | 0 | DIRECT |
| Homoserine kinase | 0 | DIRECT |
| DhaM-like | 0 | DIRECT |
| Arylamine N-acetyltransferase | 0 | DIRECT |
| SpoU-like RNA 2'-O ribose methyltransferase | 0 | DIRECT |
| MMLV matrix protein-like | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| N-deoxyribosyltransferase | 0 | DIRECT |
| Choline/Carnitine O-acyltransferase | 0 | DIRECT |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| Glucose permease-like | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | DIRECT |
| Tetrapyrrole methylase | 0 | DIRECT |
| TAF(II)230 TBP-binding fragment | 0 | DIRECT |
| CheW-like | 0 | DIRECT |
| Aspartate/ornithine carbamoyltransferase | 0 | DIRECT |
| IBR domain | 0 | DIRECT |
| Carbamate kinase | 0 | DIRECT |
| LFTR-like | 0 | DIRECT |
| RPA4359-like | 0 | DIRECT |
| Thiamin biosynthesis kinases | 0 | DIRECT |
| Histidine kinase | 0 | DIRECT |
| AmyC N-terminal domain-like | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| ZZ domain | 0 | DIRECT |
| APH phosphotransferases | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| Pyruvate kinase, C-terminal domain | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Spore coat polysaccharide biosynthesis protein SpsA | 0 | DIRECT |
| glucose-1-phosphate thymidylyltransferase | 0 | DIRECT |
| Galactokinase | 0 | DIRECT |
| ApbE-like | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| Precorrin-6Y methyltransferase (CbiT) | 0 | DIRECT |
| SSo0622-like | 0 | DIRECT |
| Methionine synthase domain | 0 | DIRECT |
| N-acetyl-l-glutamate kinase | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| NAD kinase-like | 0 | DIRECT |
| Poxvirus poly(A) polymerase catalytic subunit-like | 0 | DIRECT |
| AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC | 0 | DIRECT |
| Siroheme synthase N-terminal domain-like | 0 | DIRECT |
| alpha-1,3-galactosyltransferase-like | 0 | DIRECT |
| HTS-like | 0 | DIRECT |
| Plasmid maintenance system epsilon/zeta, toxin zeta subunit | 0 | DIRECT |
| Methyltransferase 10 domain | 0 | DIRECT |
| Holo-(acyl carrier protein) synthase ACPS | 0 | DIRECT |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | DIRECT |
| Poly A polymerase C-terminal region-like | 0 | DIRECT |
| Hexose-1-phosphate uridylyltransferase | 0 | DIRECT |
| C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
| Kinase associated domain 1, KA1 | 0 | DIRECT |
| double-SIS domain | 0 | DIRECT |
| Pyruvate phosphate dikinase, central domain | 0 | DIRECT |
| Cystathionine synthase-like | 0 | DIRECT |
| Serine acetyltransferase | 0 | DIRECT |
| UDP N-acetylglucosamine acyltransferase | 0 | DIRECT |
| RhoA-binding domain | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| Acetokinase-like | 0 | DIRECT |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
| Inosicase | 0 | DIRECT |
| Aminomethyltransferase folate-binding domain | 0 | DIRECT |
| Reverse transcriptase | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| ATP-dependent riboflavin kinase-like | 0 | DIRECT |
| Flavin-binding PAS domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Pyruvate kinase | 0 | DIRECT |
| Hypothetical RNA methyltransferase domain (HRMD) | 0 | DIRECT |
| SIAH, seven in absentia homolog | 0 | DIRECT |
| VPA0057-like | 0 | DIRECT |
| GlnE-like domain | 0 | DIRECT |
| N-acetyl transferase, NAT | 0 | DIRECT |
| SRA domain-like | 0 | DIRECT |
| Lrp/AsnC-like transcriptional regulator C-terminal domain | 0 | DIRECT |
| YrdC-like | 0 | DIRECT |
| tRNA-guanine transglycosylase | 0 | DIRECT |
| Aspartokinase allosteric domain-like | 0 | DIRECT |
| MoeA central domain-like | 0 | DIRECT |
| Transketolase C-terminal domain-like | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| PlsX-like | 0 | DIRECT |
| Ecto-ART | 0 | DIRECT |
| AstA-like | 0 | DIRECT |
| Extracellular domain of cell surface receptors | 0 | DIRECT |
| Pyruvate oxidase and decarboxylase Pyr module | 0 | DIRECT |
| Glutamine synthase adenylyltransferase GlnE, domain 2 | 0 | DIRECT |
| Methyltetrahydrofolate-utiluzing methyltransferases | 0 | DIRECT |
| Gtf glycosyltransferase | 0 | DIRECT |
| DEP domain | 0 | DIRECT |
| RcsC linker domain-like | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| MraW-like putative methyltransferases | 0 | DIRECT |
| Retroviral protease (retropepsin) | 0 | DIRECT |
| RNA polymerase alpha subunit dimerisation domain | 0 | DIRECT |
| CoA transferase beta subunit-like | 0 | DIRECT |
| MM2497-like | 0 | DIRECT |
| Galactosyltransferase LgtC | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| mRNA cap methylase | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Diacylglycerol kinase-like | 0 | DIRECT |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | DIRECT |
| LplA-like | 0 | DIRECT |
| RNA-dependent RNA-polymerase | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Biotin synthase | 0 | DIRECT |
| Spermidine synthase | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
| CheY-binding domain of CheA | 0 | DIRECT |
| Thiamin phosphate synthase | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| Arylamine N-methyltransferase | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Acyl-carrier protein (ACP) | 0 | DIRECT |
| NeuB-like | 0 | DIRECT |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
| YggJ N-terminal domain-like | 0 | DIRECT |
| ATP sulfurylase C-terminal domain | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| USP8 interacting domain | 0 | DIRECT |
| Oligosaccharide phosphorylase | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| TM1225-like predicted glycosylases | 0 | DIRECT |
| RING finger domain, C3HC4 | 0 | DIRECT |
| Mevalonate kinase | 0 | DIRECT |
| Guanido kinase catalytic domain | 0 | DIRECT |
| LuxQ-periplasmic domain-like | 0 | DIRECT |
| RNA 2'-O ribose methyltransferase substrate binding domain | 0 | DIRECT |
| IlvH-like | 0 | DIRECT |
| TRAM domain | 0 | DIRECT |
| DNA methylase TaqI, N-terminal domain | 0 | DIRECT |
| tRNA(m1G37)-methyltransferase TrmD | 0 | DIRECT |
| Type II thymidine kinase zinc finger | 0 | DIRECT |
| HPr-like | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Class-II DAHP synthetase | 0 | DIRECT |
| Motor proteins | 0 | DIRECT |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | DIRECT |
| Ephrin receptor ligand binding domain | 0 | DIRECT |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | DIRECT |
| N-myristoyl transferase, NMT | 0 | DIRECT |
| PPK N-terminal domain-like | 0 | DIRECT |
| Tpt1/KptA | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Poly A polymerase head domain-like | 0 | DIRECT |
| Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| UbiE/COQ5-like | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Glutathione S-transferase (GST), N-terminal domain | 0 | DIRECT |
| PfkB-like kinase | 0 | DIRECT |
| C5 cytosine-specific DNA methylase, DCM | 0 | DIRECT |
| Sir2 family of transcriptional regulators | 0 | DIRECT |
| Transglutaminase N-terminal domain | 0 | DIRECT |
| YggJ C-terminal domain-like | 0 | DIRECT |
| WGR domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| Arginine methyltransferase | 0 | DIRECT |
| Class I DAHP synthetase | 0 | DIRECT |
| RuBisCo LSMT catalytic domain | 0 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 3.693e-16 | DIRECT |
| Phosphotransacetylase | 7.357e-16 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 7.357e-16 | DIRECT |
| Fic-like | 0.000000000000001826 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0.00000000000001351 | DIRECT |
| Dihydropteroate synthetase | 0.0000000000002468 | DIRECT |
| PAPS reductase-like | 0.0000000000002952 | DIRECT |
| PHD domain | 0.0000000000004718 | DIRECT |
| Synaptotagmin-like (S variant) | 0.0000000000007611 | DIRECT |
| Bromodomain | 0.000000000001023 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0.000000000001255 | DIRECT |
| GGDEF domain | 0.000000000003258 | DIRECT |
| Growth factor receptor domain | 0.000000000004983 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0.00000000000568 | DIRECT |
| CCCH zinc finger | 0.000000000008446 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0.00000000001546 | DIRECT |
| Ras-binding domain, RBD | 0.00000000002181 | DIRECT |
| Ricin B-like | 0.0000000002014 | DIRECT |
| RelA/SpoT domain | 0.0000000004135 | DIRECT |
| WW domain | 0.0000000004344 | DIRECT |
| Biotinyl/lipoyl-carrier proteins and domains | 0.000000001659 | DIRECT |
| Armadillo repeat | 0.000000003401 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0.000000006109 | DIRECT |
| ADP-ribosylating toxins | 0.000000009547 | DIRECT |
| Class II viral fusion proteins C-terminal domain | 0.00000001134 | DIRECT |
| CoA transferase alpha subunit-like | 0.00000001542 | DIRECT |
| Glycosyltransferase family 36 N-terminal domain | 0.0000000269 | DIRECT |
| WD40-repeat | 0.0000002036 | DIRECT |
| Levansucrase | 0.0000002127 | DIRECT |
| Macro domain | 0.0000004929 | DIRECT |
| Heme-binding PAS domain | 0.00000168 | DIRECT |
| MogA-like | 0.000005844 | DIRECT |
| NHL repeat | 0.000007574 | DIRECT |
| Glycosyl hydrolases family 16 | 0.000008751 | DIRECT |
| Acetyl-CoA synthase | 0.00001532 | DIRECT |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.00002156 | DIRECT |
| PHP domain | 0.00002573 | DIRECT |
| FHA domain | 0.00003283 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.00003432 | DIRECT |
| Di-heme cytochrome c SoxA | 0.00003698 | DIRECT |
| Second domain of FERM | 0.00003752 | DIRECT |
| DRTGG domain | 0.0001039 | DIRECT |
| GckA/TtuD-like | 0.0001044 | DIRECT |
| PARP-type zinc finger | 0.0001861 | DIRECT |
| Ngr ectodomain-like | 0.0002176 | DIRECT |
| Transglutaminase core | 0.0003873 | DIRECT |
| LIM domain | 0.000619 | DIRECT |
| phosphatase domain of polynucleotide kinase | 0.0008174 | DIRECT |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.0008174 | DIRECT |
| NadC N-terminal domain-like | 0.0009011 | DIRECT |
| PX domain | 0.001 | INHERITED FROM: directed |
| Glycosyltransferase family 36 C-terminal domain | 0.001027 | INHERITED FROM: Kojibiose phosphorylase || Glycosyltransferases || Hexosyltransferases |
| Coronavirus NSP7-like | 0.002076 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Coronavirus NSP10-like | 0.002076 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Coronavirus NSP8-like | 0.002076 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Replicase NSP9 | 0.002076 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| DsbA-like | 0.00229 | INHERITED FROM: Glutathione transferase || Transferring alkyl or aryl groups, other than methyl groups |
| NadC C-terminal domain-like | 0.002828 | INHERITED FROM: Nicotinate-nucleotide diphosphorylase (carboxylating) || Pentosyltransferases || Glycosyltransferases |
| Ran binding protein zinc finger-like | 0.003571 | INHERITED FROM: Aminoacyltransferases || RBR-type E3 ubiquitin transferase || Acyltransferases |
| PFL-like | 0.003787 | INHERITED FROM: Transferring groups other than amino-acyl groups || Formate C-acetyltransferase || Acyltransferases |
| ADP ribosyl cyclase-like | 0.005953 | INHERITED FROM: 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase || Transferring other glycosyl groups || Glycosyltransferases |
| BadF/BadG/BcrA/BcrD-like | 0.005953 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || N-acetylglucosamine kinase || Transferring phosphorus-containing groups |
| HMG-box | 0.006424 | INHERITED FROM: Transferring one-carbon groups || [Histone H3]-lysine(4) N-trimethyltransferase || Methyltransferases |
| SAP domain | 0.009866 | INHERITED FROM: NAD(+) ADP-ribosyltransferase || Aminoacyltransferases || Acyltransferases || RING-type E3 ubiquitin transferase |
| First domain of FERM | 0.01241 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase || Aminoacyltransferases || RING-type E3 ubiquitin transferase |
| Ubiquitin-related | 0.01731 | INHERITED FROM: Aminoacyltransferases || Phosphotransferases with an alcohol group as acceptor || RBR-type E3 ubiquitin transferase || 1-phosphatidylinositol 4-kinase || Acyltransferases |
| Tropomyosin | 0.01804 | INHERITED FROM: Acyltransferases |
| NSP3A-like | 0.02139 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Starch-binding domain | 0.02641 | INHERITED FROM: Cyclomaltodextrin glucanotransferase || Glycosyltransferases || Hexosyltransferases |
| Outer arm dynein light chain 1 | 0.02674 | INHERITED FROM: Transferring alkyl or aryl groups, other than methyl groups || Protein geranylgeranyltransferase type II |
| MATH domain | 0.02946 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || RING-type E3 ubiquitin transferase |
| Leucine rich effector protein YopM | 0.03069 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || RING-type E3 ubiquitin transferase |
| Third domain of FERM | 0.03096 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase || Aminoacyltransferases || RING-type E3 ubiquitin transferase |
| Sterol carrier protein, SCP | 0.03123 | INHERITED FROM: Propanoyl-CoA C-acyltransferase || Transferring groups other than amino-acyl groups || Acyltransferases |
| GAF domain | 0.03783 | INHERITED FROM: Protein-histidine kinases || Transferring phosphorus-containing groups |
| Mason-Pfizer monkey virus matrix protein | 0.0504 | INHERITED FROM: DNA-directed DNA polymerase || RNA-directed DNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Probable phosphatase YrbI | 0.0504 | INHERITED FROM: N-acylneuraminate cytidylyltransferase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.0504 | INHERITED FROM: Fatty-acid synthase system || Transferring groups other than amino-acyl groups || [Acyl-carrier-protein] S-malonyltransferase || [Acyl-carrier-protein] S-acetyltransferase || Beta-ketoacyl-[acyl-carrier-protein] synthase I || Acyltransferases |
| Chromo domain | 0.05515 | INHERITED FROM: Histone acetyltransferase || [Histone H3]-lysine(9) N-trimethyltransferase || Transferring one-carbon groups || DNA (cytosine-5-)-methyltransferase || Methyltransferases |
| NRPS condensation domain (amide synthase) | 0.06334 | INHERITED FROM: Transferring groups other than amino-acyl groups || Phenolphthiocerol/phthiocerol/phthiodiolone dimycocerosyl transferase || Acyltransferases |
| Pyruvate oxidase and decarboxylase, middle domain | 0.06603 | INHERITED FROM: Sulfoacetaldehyde acetyltransferase || Acetolactate synthase || Acyl groups converted into alkyl groups on transfer || Transferring aldehyde or ketonic groups |
| PDZ domain | 0.08107 | INHERITED FROM: Aminoacyltransferases || Protein-serine/threonine kinases || Acyltransferases || RING-type E3 ubiquitin transferase |
| Tetratricopeptide repeat (TPR) | 0.09403 | INHERITED FROM: Aminoacyltransferases || Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || Protein O-GlcNAc transferase || Dolichyl-phosphate-mannose--protein mannosyltransferase || Glycosyltransferases || Hexosyltransferases || RING-type E3 ubiquitin transferase |
| SARS Nsp1-like | 0.1234 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases |
| Chaperone J-domain | 0.1361 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| UBA domain | 0.147 | INHERITED FROM: Aminoacyltransferases || HECT-type E3 ubiquitin transferase || Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || Acyltransferases |
| Cell wall binding repeat | 0.1507 | INHERITED FROM: Dextransucrase || Glycosyltransferases || Hexosyltransferases |
| MIT domain | 0.1663 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || Transferring phosphorus-containing groups |
| Oxygen-independent coproporphyrinogen III oxidase HemN | 0.1881 | INHERITED FROM: Transferring alkylthio groups || Transferring sulfur-containing groups || tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase |
| BCR-homology GTPase activation domain (BH-domain) | 0.1977 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Canonical RBD | 0.2117 | INHERITED FROM: Transferring one-carbon groups || [Histone H3]-lysine(4) N-trimethyltransferase || Polynucleotide adenylyltransferase || RNA uridylyltransferase || Methyltransferases || tRNA (carboxymethyluridine(34)-5-O)-methyltransferase |
| MAPEG domain | 0.2141 | INHERITED FROM: Glutathione transferase || Transferring alkyl or aryl groups, other than methyl groups |
| HD domain | 0.2212 | INHERITED FROM: Diphosphotransferases || GTP diphosphokinase || Transferring phosphorus-containing groups |
| AlkB-like | 0.2533 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || tRNA (carboxymethyluridine(34)-5-O)-methyltransferase |
| Biotin repressor (BirA) | 0.3325 | INHERITED FROM: Pantothenate kinase || Phosphotransferases with an alcohol group as acceptor |
| Sulfatase-modifying factor-like | 0.3541 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| EF-hand modules in multidomain proteins | 0.3872 | INHERITED FROM: Aminoacyltransferases || Diacylglycerol kinase (ATP) || Phosphotransferases with an alcohol group as acceptor || Acyltransferases || RING-type E3 ubiquitin transferase |
| Intein (protein splicing domain) | 0.4337 | INHERITED FROM: DNA-directed DNA polymerase || Nucleotidyltransferases |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0.5044 | INHERITED FROM: Transferring groups other than amino-acyl groups || Transferring one-carbon groups || Acyltransferases || Methyltransferases || methoxycarbonyltransferase || tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase |
| Cobalamin (vitamin B12)-binding domain | 0.5739 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Methionine synthase |
| Homoserine dehydrogenase-like | 0.6191 | INHERITED FROM: Aspartate kinase || Phosphotransferases with a carboxy group as acceptor |
| TENA/THI-4 | 0.648 | INHERITED FROM: Phosphooxymethylpyrimidine kinase || Hydroxymethylpyrimidine kinase || Phosphotransferases with a phosphate group as acceptor || Phosphotransferases with an alcohol group as acceptor |
| PLC-like (P variant) | 0.6709 | INHERITED FROM: Non-specific protein-tyrosine kinase || Aminoacyltransferases || HECT-type E3 ubiquitin transferase || Protein-serine/threonine kinases || Phosphatidylinositol-4,5-bisphosphate 3-kinase || Phosphatidylinositol 3-kinase || Transferring phosphorus-containing groups || Protein kinase C |
| MaoC-like | 0.8215 | INHERITED FROM: Fatty-acyl-CoA synthase system || Transferring groups other than amino-acyl groups || [Acyl-carrier-protein] S-malonyltransferase || [Acyl-carrier-protein] S-acetyltransferase || Acyltransferases |
| Quinoprotein alcohol dehydrogenase-like | 0.8829 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Biotin holoenzyme synthetase | 0.9044 | INHERITED FROM: Pantothenate kinase |
| DmpG/LeuA communication domain-like | 0.9185 | INHERITED FROM: Acyl groups converted into alkyl groups on transfer || 2-isopropylmalate synthase || Acyltransferases |
| Caspase recruitment domain, CARD | 0.964 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase || Aminoacyltransferases || Non-specific serine/threonine protein kinase || RING-type E3 ubiquitin transferase |
| cAMP-binding domain | 0.9807 | INHERITED FROM: cGMP-dependent protein kinase || Protein-serine/threonine kinases |
| CoA-binding domain | 1 | INHERITED FROM: ATP citrate synthase || Acyl groups converted into alkyl groups on transfer || Acyltransferases |
| Branched-chain alpha-keto acid dehydrogenase PP module | 1 | INHERITED FROM: Dihydrolipoyllysine-residue succinyltransferase || 2-hydroxy-3-oxoadipate synthase || Transferring aldehyde or ketonic groups |
| PP-loop ATPase | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
| Dihydrofolate reductases | 1 | INHERITED FROM: Transferring one-carbon groups || Thymidylate synthase || Methyltransferases |
| Ribonuclease H | 1 | INHERITED FROM: DNA-directed DNA polymerase || RNA-directed DNA polymerase || Nucleotidyltransferases |
| ALDH-like | 1 | INHERITED FROM: Glutamate 5-kinase |
| Elongation factors | 1 | INHERITED FROM: Adenylyl-sulfate kinase || Nucleotidyltransferases || Transferring phosphorus-containing groups || Sulfate adenylyltransferase |
| Acetyl-CoA synthetase-like | 1 | INHERITED FROM: Transferring groups other than amino-acyl groups || Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Carboxy- and carbamoyltransferases || Aspartate carbamoyltransferase |
| Succinyl-CoA synthetase, beta-chain, N-terminal domain | 1 | INHERITED FROM: ATP citrate synthase |
| Biotin biosynthesis protein BioH | 1 | INHERITED FROM: Malonyl-[acyl-carrier protein] O-methyltransferase |
| Dual specificity phosphatase-like | 1 | INHERITED FROM: mRNA guanylyltransferase |
| Ribonuclease Rh-like | 1 | INHERITED FROM: RNA-directed RNA polymerase |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 1 | INHERITED FROM: mRNA guanylyltransferase |
| PurM N-terminal domain-like | 1 | INHERITED FROM: Thiamine-phosphate kinase || Selenide, water dikinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase |
| Serine carboxypeptidase-like | 1 | INHERITED FROM: Sinapoylglucose--sinapoylglucose O-sinapoyltransferase |
| Class I aldolase | 1 | INHERITED FROM: Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase || 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase || Transaldolase || 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase || Transferring aldehyde or ketonic groups |
| DNase I-like | 1 | INHERITED FROM: RNA-directed DNA polymerase |
| PUA domain | 1 | INHERITED FROM: Pentosyltransferases || tRNA-guanine(15) transglycosylase || Glycosyltransferases |
| Class I glutamine amidotransferases (GAT) | 1 | INHERITED FROM: Aminodeoxychorismate synthase |
| Globins | 1 | INHERITED FROM: Diguanylate cyclase |
| Dehydroquinate synthase, DHQS | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than methyl groups || Shikimate kinase || Phosphotransferases with an alcohol group as acceptor || 3-phosphoshikimate 1-carboxyvinyltransferase |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: Carboxy- and carbamoyltransferases || Aspartate carbamoyltransferase |
| mono-SIS domain | 1 | INHERITED FROM: Glucokinase |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 1 | INHERITED FROM: Lysyltransferase |
| UDP-N-acetylglucosamine 2-epimerase | 1 | INHERITED FROM: N-acylmannosamine kinase || Phosphotransferases with an alcohol group as acceptor |
| DNA ligase | 1 | INHERITED FROM: NAD(+) ADP-ribosyltransferase |
| BC C-terminal domain-like | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
| PurM C-terminal domain-like | 1 | INHERITED FROM: Thiamine-phosphate kinase || Selenide, water dikinase || Phosphotransferases with paired acceptors || Phosphoribosylglycinamide formyltransferase |
| FMN-linked oxidoreductases | 1 | INHERITED FROM: Phosphoglycerol geranylgeranyltransferase || Transferring alkyl or aryl groups, other than methyl groups || Heptaprenylglyceryl phosphate synthase |
| Glutamine synthetase, N-terminal domain | 1 | INHERITED FROM: Protein S-acyltransferase |
| Tyrosine-dependent oxidoreductases | 1 | INHERITED FROM: Lovastatin nonaketide synthase || Fatty-acid synthase system || 10-deoxymethynolide syntase || UDP-4-amino-4-deoxy-L-arabinose formyltransferase || Hydroxymethyl-, formyl- and related transferases || [Acyl-carrier-protein] S-malonyltransferase || [Acyl-carrier-protein] S-acetyltransferase || 2-methylbutanoate polyketide synthase || Beta-ketoacyl-[acyl-carrier-protein] synthase I || 6-deoxyerythronolide-B synthase || 6-methylsalicylic acid synthase || Narbonolide synthase |
| ADC synthase | 1 | INHERITED FROM: Transaminases || Transferring nitrogenous groups || Aminodeoxychorismate synthase |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 1 | INHERITED FROM: Carboxy- and carbamoyltransferases || Aspartate carbamoyltransferase |
| Aminoacid dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase |
| RecA protein-like (ATPase-domain) | 1 | INHERITED FROM: Adenosylcobinamide kinase || Corrinoid adenosyltransferase || Adenosylcobinamide-phosphate guanylyltransferase |
| Trehalose-phosphatase | 1 | INHERITED FROM: Alpha,alpha-trehalose-phosphate synthase (UDP-forming) || Hexosyltransferases |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than methyl groups || Cysteate synthase || N-(2-amino-2-carboxyethyl)-L-glutamate synthase || Cysteine synthase |
| G proteins | 1 | INHERITED FROM: Adenylyl-sulfate kinase || Nucleotidyltransferases || Sulfate adenylyltransferase |
| beta-Lactamase/D-ala carboxypeptidase | 1 | INHERITED FROM: Peptidoglycan glycosyltransferase || Glycosyltransferases || Hexosyltransferases |
| Alcohol dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Fatty-acid synthase system || [Acyl-carrier-protein] S-malonyltransferase || [Acyl-carrier-protein] S-acetyltransferase || 2-methylbutanoate polyketide synthase || Beta-ketoacyl-[acyl-carrier-protein] synthase I |
| Crotonase-like | 1 | INHERITED FROM: Histone acetyltransferase |
| Achaeal helicase C-terminal domain | 1 | INHERITED FROM: DNA-directed DNA polymerase |
| FAD-linked oxidases, N-terminal domain | 1 | INHERITED FROM: Alkylglycerone-phosphate synthase |
| MutT-like | 1 | INHERITED FROM: ADP-D-ribose pyrophosphorylase |
| Cyclophilin (peptidylprolyl isomerase) | 1 | INHERITED FROM: Aminoacyltransferases || RING-type E3 ubiquitin transferase |
| BC N-terminal domain-like | 1 | INHERITED FROM: Aspartate carbamoyltransferase || Phosphoribosylglycinamide formyltransferase |
| CheY-related | 1 | INHERITED FROM: Protein-histidine kinases |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
| Uroporphyrinogen decarboxylase, UROD | 1 | INHERITED FROM: methyltransferase |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 1 | INHERITED FROM: Dihydrolipoyllysine-residue succinyltransferase || 2-hydroxy-3-oxoadipate synthase || Transferring aldehyde or ketonic groups |
| IpsF-like | 1 | INHERITED FROM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) | 1 | INHERITED FROM: Phosphotransferases with a phosphate group as acceptor || (d)CMP kinase |
| HpcH/HpaI aldolase | 1 | INHERITED FROM: Acyl groups converted into alkyl groups on transfer || Malate synthase |
| Alcohol dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Fatty-acid synthase system || [Acyl-carrier-protein] S-malonyltransferase || [Acyl-carrier-protein] S-acetyltransferase || 2-methylbutanoate polyketide synthase || Beta-ketoacyl-[acyl-carrier-protein] synthase I |
| Succinyl-CoA synthetase domains | 1 | INHERITED FROM: ATP citrate synthase || Acyl groups converted into alkyl groups on transfer |
| CBS-domain pair | 1 | INHERITED FROM: Homoserine O-acetyltransferase || Transferring groups other than amino-acyl groups || Acyltransferases |
| Nitrogenase iron protein-like | 1 | INHERITED FROM: Non-specific protein-tyrosine kinase |
| Anticodon-binding domain | 1 | INHERITED FROM: Lysyltransferase |
| PA domain | 1 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || RING-type E3 ubiquitin transferase |
| Glutamine synthetase catalytic domain | 1 | INHERITED FROM: Protein S-acyltransferase |
| MoCo biosynthesis proteins | 1 | INHERITED FROM: 23S rRNA (adenine(2503)-C(2))-methyltransferase |
| Decarboxylase | 1 | INHERITED FROM: Orotate phosphoribosyltransferase |
| dUTPase-like | 1 | INHERITED FROM: DNA-directed DNA polymerase || RNA-directed DNA polymerase |
| Extended AAA-ATPase domain | 1 | INHERITED FROM: DNA-directed DNA polymerase |
| BC ATP-binding domain-like | 1 | INHERITED FROM: Aspartate carbamoyltransferase || Phosphoribosylglycinamide formyltransferase |
| Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| Shikimate dehydrogenase-like | 1 | INHERITED FROM: Transferring alkyl or aryl groups, other than methyl groups || Shikimate kinase || Phosphotransferases with an alcohol group as acceptor || 3-phosphoshikimate 1-carboxyvinyltransferase |
| D-aminoacid oxidase-like | 1 | INHERITED FROM: Thiazole synthase |
| Kringle modules | 1 | INHERITED FROM: Protein-tyrosine kinases || Receptor protein-tyrosine kinase |
| DHN aldolase/epimerase | 1 | INHERITED FROM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase || Diphosphotransferases || Dihydropteroate synthase |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| alpha-D-mannose-specific plant lectins | 0 | Direct |
| Guanidinoacetate methyltransferase | 0 | Direct |
| Glycogenin | 0 | Direct |
| Galactoside acetyltransferase-like | 0 | Direct |
| hypothetical RNA methyltransferase | 0 | Direct |
| Archaeal tRNA CCA-adding enzyme | 0 | Direct |
| Chemotaxis receptor methyltransferase CheR, C-terminal domain | 0 | Direct |
| YhiQ-like | 0 | Direct |
| BphP N-terminal domain-like | 0 | Direct |
| HTLV-II matrix protein | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| TK-like Pyr module | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| KaiB-like | 0 | Direct |
| CofD-like | 0 | Direct |
| mRNA cap (Guanine N-7) methyltransferase | 0 | Direct |
| Leucine zipper domain | 0 | Direct |
| RNA polymerase omega subunit | 0 | Direct |
| Trimerization domain of TRAF | 0 | Direct |
| AD-003 protein-like | 0 | Direct |
| Glutathione S-transferase (GST), C-terminal domain | 0 | Direct |
| Glutaminyl-peptide cyclotransferase-like | 0 | Direct |
| Thiamin pyrophosphokinase, catalytic domain | 0 | Direct |
| Poly(ADP-ribose) polymerase, C-terminal domain | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| DNA polymerase beta-like, second domain | 0 | Direct |
| PTS system, Fructose specific IIB subunit-like | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| GrpB-like | 0 | Direct |
| YgbK-like | 0 | Direct |
| CoaX-like | 0 | Direct |
| Polygalacturonase inhibiting protein PGIP | 0 | Direct |
| T7 RNA polymerase | 0 | Direct |
| PAS domain of steroid receptor coactivator 1A, NCo-A1 | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| DhaL-like | 0 | Direct |
| ArgJ-like | 0 | Direct |
| N-acetylglucosaminyltransferase I | 0 | Direct |
| Methyl-coenzyme M reductase alpha and beta chain N-terminal domain | 0 | Direct |
| UBC-related | 0 | Direct |
| RIO1-like kinases | 0 | Direct |
| Fumble-like | 0 | Direct |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | Direct |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | Direct |
| Glycosyl transferases group 1 | 0 | Direct |
| PAPS sulfotransferase | 0 | Direct |
| Glucose-inhibited division protein B (GidB) | 0 | Direct |
| N-6 DNA Methylase-like | 0 | Direct |
| PPK middle domain-like | 0 | Direct |
| ThiG-like | 0 | Direct |
| Plant O-methyltransferase, N-terminal domain | 0 | Direct |
| PTS IIb component | 0 | Direct |
| Viral proteases | 0 | Direct |
| AF1531-like | 0 | Direct |
| SPRY domain | 0 | Direct |
| PyrH-like | 0 | Direct |
| Ssp2 C-terminal domain-like | 0 | Direct |
| Plexin repeat | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Protein kinases, catalytic subunit | 0 | Direct |
| ADP-specific Phosphofructokinase/Glucokinase | 0 | Direct |
| Receiver domain of the ethylene receptor | 0 | Direct |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | Direct |
| Sensory domain of two-component sensor kinase | 0 | Direct |
| YhhF-like | 0 | Direct |
| Amidinotransferase | 0 | Direct |
| Plant O-methyltransferase, C-terminal domain | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| Phytochelatin synthase | 0 | Direct |
| Thi4-like | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| RWD domain | 0 | Direct |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
| Viral cysteine protease of trypsin fold | 0 | Direct |
| TrmB-like | 0 | Direct |
| Chemotaxis protein CheA P1 domain | 0 | Direct |
| TRM1-like | 0 | Direct |
| Pyruvate phosphate dikinase, N-terminal domain | 0 | Direct |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
| Putative methyltransferase TM0872, insert domain | 0 | Direct |
| CoA-transferase family III (CaiB/BaiF) | 0 | Direct |
| FCH domain | 0 | Direct |
| Ribonuclease PH domain 1-like | 0 | Direct |
| ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain | 0 | Direct |
| RmsB N-terminal domain-like | 0 | Direct |
| TK-like PP module | 0 | Direct |
| Transcriptional factor domain | 0 | Direct |
| Molybdopterin synthase subunit MoaE | 0 | Direct |
| Mib/herc2 domain | 0 | Direct |
| Malate synthase G | 0 | Direct |
| L domain | 0 | Direct |
| Archaeal tRNA CCA-adding enzyme substrate-binding domain | 0 | Direct |
| PB1 domain | 0 | Direct |
| Thiolase-related | 0 | Direct |
| tRNA(1-methyladenosine) methyltransferase-like | 0 | Direct |
| Phosphomethylpyrimidine kinase C-terminal domain-like | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| ROK | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| Archaeal tRNA CCA-adding enzyme catalytic domain | 0 | Direct |
| IIA domain of mannitol-specific and ntr phosphotransferase EII | 0 | Direct |
| AF0751-like | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| SH2 domain | 0 | Direct |
| Sporulation response regulatory protein Spo0B | 0 | Direct |
| Glycine N-methyltransferase | 0 | Direct |
| HAMP domain | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain | 0 | Direct |
| L27 domain | 0 | Direct |
| RpiR-like | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Shikimate kinase (AroK) | 0 | Direct |
| MIR domain | 0 | Direct |
| PBP transglycosylase domain-like | 0 | Direct |
| E-set domains of sugar-utilizing enzymes | 0 | Direct |
| Riboflavin synthase | 0 | Direct |
| NOL1/NOP2/sun | 0 | Direct |
| 4'-Phosphopantetheinyl transferase SFP | 0 | Direct |
| Adenylyltransferase | 0 | Direct |
| MoeA N-terminal region -like | 0 | Direct |
| Salicylic acid carboxyl methyltransferase (SAMT) | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| HMGL-like | 0 | Direct |
| Multidomain sulfurtransferase (rhodanese) | 0 | Direct |
| DNA polymerase III chi subunit | 0 | Direct |
| Adenosine-5'phosphosulfate kinase (APS kinase) | 0 | Direct |
| RPB6 | 0 | Direct |
| CTP-dependent riboflavin kinase-like | 0 | Direct |
| Choline kinase | 0 | Direct |
| FMDV leader protease | 0 | Direct |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | Direct |
| Histone lysine methyltransferases | 0 | Direct |
| Methicillin resistance protein FemA probable tRNA-binding arm | 0 | Direct |
| Filamin repeat (rod domain) | 0 | Direct |
| 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase IspE | 0 | Direct |
| Insert subdomain of RNA polymerase alpha subunit | 0 | Direct |
| YbeA-like | 0 | Direct |
| BRCT domain | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
| RNA helicase | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| Classic zinc finger, C2H2 | 0 | Direct |
| UDPGT-like | 0 | Direct |
| Trehalose-6-phosphate synthase, OtsA | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| rRNA adenine dimethylase-like | 0 | Direct |
| Outer membrane enzyme PagP | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| Transcription factor IIB (TFIIB), core domain | 0 | Direct |
| MoeA C-terminal domain-like | 0 | Direct |
| Type II thymidine kinase | 0 | Direct |
| THUMP domain | 0 | Direct |
| Glucokinase | 0 | Direct |
| SepSecS-like | 0 | Direct |
| Swapped Polo-box domain | 0 | Direct |
| ThiI-like | 0 | Direct |
| RNA methyltransferase FtsJ | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| DNA polymerase beta-like | 0 | Direct |
| GlmU C-terminal domain-like | 0 | Direct |
| FucT-like | 0 | Direct |
| Ketopantoate hydroxymethyltransferase PanB | 0 | Direct |
| Type II DNA methylase | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | Direct |
| Pyruvate oxidase and decarboxylase PP module | 0 | Direct |
| Gluconate kinase | 0 | Direct |
| Thiopurine S-methyltransferase | 0 | Direct |
| ATP sulfurylase catalytic domain | 0 | Direct |
| Glucose permease domain IIB | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Cobalamin adenosyltransferase | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| Nsp15 N-terminal domain-like | 0 | Direct |
| Thymidylate synthase-complementing protein Thy1 | 0 | Direct |
| Retrovirus capsid protein C-terminal domain | 0 | Direct |
| AAT-like | 0 | Direct |
| FAT domain of focal adhesion kinase | 0 | Direct |
| APC10-like | 0 | Direct |
| PWWP domain | 0 | Direct |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| CbiD-like | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| Cold shock DNA-binding domain-like | 0 | Direct |
| Calmodulin-like | 0 | Direct |
| MarR-like transcriptional regulators | 0 | Direct |
| Legume lectins | 0 | Direct |
| Post formyltransferase domain | 0 | Direct |
| Hypothetical protein MJ0882 | 0 | Direct |
| Leucine carboxy methyltransferase Ppm1 | 0 | Direct |
| Glycerol kinase | 0 | Direct |
| Protein-L-isoaspartyl O-methyltransferase | 0 | Direct |
| CPH domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Chalcone synthase-like | 0 | Direct |
| Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain | 0 | Direct |
| Peptidoglycan biosynthesis glycosyltransferase MurG | 0 | Direct |
| CAT-like | 0 | Direct |
| beta-lactamase inhibitor protein-II, BLIP-II | 0 | Direct |
| AF1056-like | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| RNA polymerase subunit RPB10 | 0 | Direct |
| QueA-like | 0 | Direct |
| Monomethylamine methyltransferase MtmB | 0 | Direct |
| Chromo barrel domain | 0 | Direct |
| Siroheme synthase middle domains-like | 0 | Direct |
| Archaeosine tRNA-guanine transglycosylase, C2 domain | 0 | Direct |
| AFP III-like domain | 0 | Direct |
| Molybdenum cofactor biosynthesis protein MobA | 0 | Direct |
| Phosphate binding protein-like | 0 | Direct |
| Methionine synthase SAM-binding domain | 0 | Direct |
| Exostosin | 0 | Direct |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | Direct |
| Mycobacterial antigens | 0 | Direct |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | Direct |
| Cobalamin-independent methionine synthase | 0 | Direct |
| I set domains | 0 | Direct |
| Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
| Variant RING domain | 0 | Direct |
| Homeodomain | 0 | Direct |
| Zinc hairpin stack | 0 | Direct |
| TAZ domain | 0 | Direct |
| Molybdenum cofactor biosynthesis protein MoeB | 0 | Direct |
| YeaZ-like | 0 | Direct |
| RBP11/RpoL | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| Met-10+ protein-like | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| COMT-like | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| NadA-like | 0 | Direct |
| N6 adenine-specific DNA methylase, DAM | 0 | Direct |
| (Uracil-5-)-methyltransferase | 0 | Direct |
| Pyridoxine 5'-phosphate synthase | 0 | Direct |
| Squalene synthase | 0 | Direct |
| V set domains (antibody variable domain-like) | 0 | Direct |
| mRNA capping enzyme | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| Pentapeptide repeats | 0 | Direct |
| FabD-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| O-acetyltransferase | 0 | Direct |
| Protein prenyltransferases | 0 | Direct |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | Direct |
| Immunodeficiency virus matrix proteins | 0 | Direct |
| Pyruvate phosphate dikinase, C-terminal domain | 0 | Direct |
| DAK1 | 0 | Direct |
| Single-domain sulfurtransferase | 0 | Direct |
| Caliciviridae-like VP | 0 | Direct |
| FemXAB nonribosomal peptidyltransferases | 0 | Direct |
| Cytidylytransferase | 0 | Direct |
| Histamine methyltransferase | 0 | Direct |
| Ankyrin repeat | 0 | Direct |
| Polyphosphate kinase C-terminal domain | 0 | Direct |
| Phosphoglycerate kinase | 0 | Direct |
| Nsp15 C-terminal domain-like | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| Mycolic acid cyclopropane synthase | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| MHCK/EF2 kinase | 0 | Direct |
| Formyltransferase | 0 | Direct |
| Docking domain B of the erythromycin polyketide synthase (DEBS) | 0 | Direct |
| Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain | 0 | Direct |
| Enolpyruvate transferase, EPT | 0 | Direct |
| Trm112p-like | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Phosphoribosyltransferases (PRTases) | 0 | Direct |
| Glycerate kinase I | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| PTS system, Lactose/Cellobiose specific IIB subunit | 0 | Direct |
| Notch domain | 0 | Direct |
| N5-glutamine methyltransferase, HemK | 0 | Direct |
| YojJ-like | 0 | Direct |
| Pyruvate kinase beta-barrel domain | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| Methyl-coenzyme M reductase gamma chain | 0 | Direct |
| ATP sulfurylase N-terminal domain | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | Direct |
| AmyC C-terminal domain-like | 0 | Direct |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | Direct |
| mannose-1-phosphate guanylyl transferase | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | Direct |
| Nucleotide and nucleoside kinases | 0 | Direct |
| Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
| Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | Direct |
| Autoinducer synthetase | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Deoxyhypusine synthase, DHS | 0 | Direct |
| 1,3-glucuronyltransferase | 0 | Direct |
| Prenyltransferase-like | 0 | Direct |
| Aminoglycoside 3-N-acetyltransferase-like | 0 | Direct |
| Lumazine synthase | 0 | Direct |
| N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system | 0 | Direct |
| GAG polyprotein M-domain | 0 | Direct |
| Phosphoribulokinase/pantothenate kinase | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| RPB5 | 0 | Direct |
| Phytochrome-specific domain | 0 | Direct |
| CHY zinc finger | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | Direct |
| GABA-aminotransferase-like | 0 | Direct |
| Retroviral integrase, catalytic domain | 0 | Direct |
| U-box | 0 | Direct |
| Homoserine kinase | 0 | Direct |
| DhaM-like | 0 | Direct |
| Arylamine N-acetyltransferase | 0 | Direct |
| SpoU-like RNA 2'-O ribose methyltransferase | 0 | Direct |
| MMLV matrix protein-like | 0 | Direct |
| Hexokinase | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| N-deoxyribosyltransferase | 0 | Direct |
| Choline/Carnitine O-acyltransferase | 0 | Direct |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| Glucose permease-like | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | Direct |
| Tetrapyrrole methylase | 0 | Direct |
| TAF(II)230 TBP-binding fragment | 0 | Direct |
| CheW-like | 0 | Direct |
| Aspartate/ornithine carbamoyltransferase | 0 | Direct |
| IBR domain | 0 | Direct |
| Carbamate kinase | 0 | Direct |
| LFTR-like | 0 | Direct |
| RPA4359-like | 0 | Direct |
| Thiamin biosynthesis kinases | 0 | Direct |
| Histidine kinase | 0 | Direct |
| AmyC N-terminal domain-like | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| ZZ domain | 0 | Direct |
| APH phosphotransferases | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| Pyruvate kinase, C-terminal domain | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Spore coat polysaccharide biosynthesis protein SpsA | 0 | Direct |
| glucose-1-phosphate thymidylyltransferase | 0 | Direct |
| Galactokinase | 0 | Direct |
| ApbE-like | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| Precorrin-6Y methyltransferase (CbiT) | 0 | Direct |
| SSo0622-like | 0 | Direct |
| Methionine synthase domain | 0 | Direct |
| N-acetyl-l-glutamate kinase | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| NAD kinase-like | 0 | Direct |
| Poxvirus poly(A) polymerase catalytic subunit-like | 0 | Direct |
| AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC | 0 | Direct |
| Siroheme synthase N-terminal domain-like | 0 | Direct |
| alpha-1,3-galactosyltransferase-like | 0 | Direct |
| HTS-like | 0 | Direct |
| Plasmid maintenance system epsilon/zeta, toxin zeta subunit | 0 | Direct |
| Methyltransferase 10 domain | 0 | Direct |
| Holo-(acyl carrier protein) synthase ACPS | 0 | Direct |
| Biotin dependent carboxylase carboxyltransferase domain | 0 | Direct |
| Poly A polymerase C-terminal region-like | 0 | Direct |
| Hexose-1-phosphate uridylyltransferase | 0 | Direct |
| C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
| Kinase associated domain 1, KA1 | 0 | Direct |
| double-SIS domain | 0 | Direct |
| Pyruvate phosphate dikinase, central domain | 0 | Direct |
| Cystathionine synthase-like | 0 | Direct |
| Serine acetyltransferase | 0 | Direct |
| UDP N-acetylglucosamine acyltransferase | 0 | Direct |
| RhoA-binding domain | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| Acetokinase-like | 0 | Direct |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
| Inosicase | 0 | Direct |
| Aminomethyltransferase folate-binding domain | 0 | Direct |
| Reverse transcriptase | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| ATP-dependent riboflavin kinase-like | 0 | Direct |
| Flavin-binding PAS domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Pyruvate kinase | 0 | Direct |
| Hypothetical RNA methyltransferase domain (HRMD) | 0 | Direct |
| SIAH, seven in absentia homolog | 0 | Direct |
| VPA0057-like | 0 | Direct |
| GlnE-like domain | 0 | Direct |
| N-acetyl transferase, NAT | 0 | Direct |
| SRA domain-like | 0 | Direct |
| Lrp/AsnC-like transcriptional regulator C-terminal domain | 0 | Direct |
| YrdC-like | 0 | Direct |
| tRNA-guanine transglycosylase | 0 | Direct |
| Aspartokinase allosteric domain-like | 0 | Direct |
| MoeA central domain-like | 0 | Direct |
| Transketolase C-terminal domain-like | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| PlsX-like | 0 | Direct |
| Ecto-ART | 0 | Direct |
| AstA-like | 0 | Direct |
| Extracellular domain of cell surface receptors | 0 | Direct |
| Pyruvate oxidase and decarboxylase Pyr module | 0 | Direct |
| Glutamine synthase adenylyltransferase GlnE, domain 2 | 0 | Direct |
| Methyltetrahydrofolate-utiluzing methyltransferases | 0 | Direct |
| Gtf glycosyltransferase | 0 | Direct |
| DEP domain | 0 | Direct |
| RcsC linker domain-like | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| MraW-like putative methyltransferases | 0 | Direct |
| Retroviral protease (retropepsin) | 0 | Direct |
| RNA polymerase alpha subunit dimerisation domain | 0 | Direct |
| CoA transferase beta subunit-like | 0 | Direct |
| MM2497-like | 0 | Direct |
| Galactosyltransferase LgtC | 0 | Direct |
| SH3-domain | 0 | Direct |
| mRNA cap methylase | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Diacylglycerol kinase-like | 0 | Direct |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | Direct |
| LplA-like | 0 | Direct |
| RNA-dependent RNA-polymerase | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Biotin synthase | 0 | Direct |
| Spermidine synthase | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | Direct |
| CCHHC domain | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| DnaQ-like 3'-5' exonuclease | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
| CheY-binding domain of CheA | 0 | Direct |
| Thiamin phosphate synthase | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Cyclin | 0 | Direct |
| Arylamine N-methyltransferase | 0 | Direct |
| WWE domain | 0 | Direct |
| Acyl-carrier protein (ACP) | 0 | Direct |
| NeuB-like | 0 | Direct |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
| YggJ N-terminal domain-like | 0 | Direct |
| ATP sulfurylase C-terminal domain | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| USP8 interacting domain | 0 | Direct |
| Oligosaccharide phosphorylase | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| TM1225-like predicted glycosylases | 0 | Direct |
| RING finger domain, C3HC4 | 0 | Direct |
| Mevalonate kinase | 0 | Direct |
| Guanido kinase catalytic domain | 0 | Direct |
| LuxQ-periplasmic domain-like | 0 | Direct |
| RNA 2'-O ribose methyltransferase substrate binding domain | 0 | Direct |
| IlvH-like | 0 | Direct |
| TRAM domain | 0 | Direct |
| DNA methylase TaqI, N-terminal domain | 0 | Direct |
| tRNA(m1G37)-methyltransferase TrmD | 0 | Direct |
| Type II thymidine kinase zinc finger | 0 | Direct |
| HPr-like | 0 | Direct |
| LanC-like | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Class-II DAHP synthetase | 0 | Direct |
| Motor proteins | 0 | Direct |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | Direct |
| Ephrin receptor ligand binding domain | 0 | Direct |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
| beta 1,4 galactosyltransferase (b4GalT1) | 0 | Direct |
| N-myristoyl transferase, NMT | 0 | Direct |
| PPK N-terminal domain-like | 0 | Direct |
| Tpt1/KptA | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Poly A polymerase head domain-like | 0 | Direct |
| Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| UbiE/COQ5-like | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Sema domain | 0 | Direct |
| Glutathione S-transferase (GST), N-terminal domain | 0 | Direct |
| PfkB-like kinase | 0 | Direct |
| C5 cytosine-specific DNA methylase, DCM | 0 | Direct |
| Sir2 family of transcriptional regulators | 0 | Direct |
| Transglutaminase N-terminal domain | 0 | Direct |
| YggJ C-terminal domain-like | 0 | Direct |
| WGR domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| Arginine methyltransferase | 0 | Direct |
| Class I DAHP synthetase | 0 | Direct |
| RuBisCo LSMT catalytic domain | 0 | Direct |
| Pleckstrin-homology domain (PH domain) | 3.693e-16 | Direct |
| Phosphotransacetylase | 7.357e-16 | Direct |
| Gamma-glutamyltranspeptidase-like | 7.357e-16 | Direct |
| Fic-like | 0.000000000000001826 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0.00000000000001351 | Direct |
| Dihydropteroate synthetase | 0.0000000000002468 | Direct |
| PAPS reductase-like | 0.0000000000002952 | Direct |
| PHD domain | 0.0000000000004718 | Direct |
| Synaptotagmin-like (S variant) | 0.0000000000007611 | Direct |
| Bromodomain | 0.000000000001023 | Direct |
| 5' to 3' exonuclease catalytic domain | 0.000000000001255 | Direct |
| GGDEF domain | 0.000000000003258 | Direct |
| Growth factor receptor domain | 0.000000000004983 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0.00000000000568 | Direct |
| CCCH zinc finger | 0.000000000008446 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0.00000000001546 | Direct |
| Ras-binding domain, RBD | 0.00000000002181 | Direct |
| Ricin B-like | 0.0000000002014 | Direct |
| RelA/SpoT domain | 0.0000000004135 | Direct |
| WW domain | 0.0000000004344 | Direct |
| Biotinyl/lipoyl-carrier proteins and domains | 0.000000001659 | Direct |
| Armadillo repeat | 0.000000003401 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0.000000006109 | Direct |
| ADP-ribosylating toxins | 0.000000009547 | Direct |
| Class II viral fusion proteins C-terminal domain | 0.00000001134 | Direct |
| CoA transferase alpha subunit-like | 0.00000001542 | Direct |
| Glycosyltransferase family 36 N-terminal domain | 0.0000000269 | Direct |
| WD40-repeat | 0.0000002036 | Direct |
| Levansucrase | 0.0000002127 | Direct |
| Macro domain | 0.0000004929 | Direct |
| Heme-binding PAS domain | 0.00000168 | Direct |
| MogA-like | 0.000005844 | Direct |
| NHL repeat | 0.000007574 | Direct |
| Glycosyl hydrolases family 16 | 0.000008751 | Direct |
| Acetyl-CoA synthase | 0.00001532 | Direct |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.00002156 | Direct |
| PHP domain | 0.00002573 | Direct |
| FHA domain | 0.00003283 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.00003432 | Direct |
| Di-heme cytochrome c SoxA | 0.00003698 | Direct |
| Second domain of FERM | 0.00003752 | Direct |
| DRTGG domain | 0.0001039 | Direct |
| GckA/TtuD-like | 0.0001044 | Direct |
| PARP-type zinc finger | 0.0001861 | Direct |
| Ngr ectodomain-like | 0.0002176 | Direct |
| Transglutaminase core | 0.0003873 | Direct |
| LIM domain | 0.000619 | Direct |
| phosphatase domain of polynucleotide kinase | 0.0008174 | Direct |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.0008174 | Direct |
| NadC N-terminal domain-like | 0.0009011 | Direct |
| PX domain | 0.001 | Inherited |
| Glycosyltransferase family 36 C-terminal domain | 0.001027 | Inherited |
| Coronavirus NSP7-like | 0.002076 | Inherited |
| Coronavirus NSP10-like | 0.002076 | Inherited |
| Coronavirus NSP8-like | 0.002076 | Inherited |
| Replicase NSP9 | 0.002076 | Inherited |
| DsbA-like | 0.00229 | Inherited |
| NadC C-terminal domain-like | 0.002828 | Inherited |
| Ran binding protein zinc finger-like | 0.003571 | Inherited |
| PFL-like | 0.003787 | Inherited |
| ADP ribosyl cyclase-like | 0.005953 | Inherited |
| BadF/BadG/BcrA/BcrD-like | 0.005953 | Inherited |
| HMG-box | 0.006424 | Inherited |
| SAP domain | 0.009866 | Inherited |
| First domain of FERM | 0.01241 | Inherited |
| Ubiquitin-related | 0.01731 | Inherited |
| Tropomyosin | 0.01804 | Inherited |
| NSP3A-like | 0.02139 | Inherited |
| Starch-binding domain | 0.02641 | Inherited |
| Outer arm dynein light chain 1 | 0.02674 | Inherited |
| MATH domain | 0.02946 | Inherited |
| Leucine rich effector protein YopM | 0.03069 | Inherited |
| Third domain of FERM | 0.03096 | Inherited |
| Sterol carrier protein, SCP | 0.03123 | Inherited |
| GAF domain | 0.03783 | Inherited |
| Mason-Pfizer monkey virus matrix protein | 0.0504 | Inherited |
| Probable phosphatase YrbI | 0.0504 | Inherited |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.0504 | Inherited |
| Chromo domain | 0.05515 | Inherited |
| NRPS condensation domain (amide synthase) | 0.06334 | Inherited |
| Pyruvate oxidase and decarboxylase, middle domain | 0.06603 | Inherited |
| PDZ domain | 0.08107 | Inherited |
| Tetratricopeptide repeat (TPR) | 0.09403 | Inherited |
| SARS Nsp1-like | 0.1234 | Inherited |
| Chaperone J-domain | 0.1361 | Inherited |
| UBA domain | 0.147 | Inherited |
| Cell wall binding repeat | 0.1507 | Inherited |
| MIT domain | 0.1663 | Inherited |
| Oxygen-independent coproporphyrinogen III oxidase HemN | 0.1881 | Inherited |
| BCR-homology GTPase activation domain (BH-domain) | 0.1977 | Inherited |
| Canonical RBD | 0.2117 | Inherited |
| MAPEG domain | 0.2141 | Inherited |
| HD domain | 0.2212 | Inherited |
| AlkB-like | 0.2533 | Inherited |
| Biotin repressor (BirA) | 0.3325 | Inherited |
| Sulfatase-modifying factor-like | 0.3541 | Inherited |
| EF-hand modules in multidomain proteins | 0.3872 | Inherited |
| Intein (protein splicing domain) | 0.4337 | Inherited |
| Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0.5044 | Inherited |
| Cobalamin (vitamin B12)-binding domain | 0.5739 | Inherited |
| Homoserine dehydrogenase-like | 0.6191 | Inherited |
| TENA/THI-4 | 0.648 | Inherited |
| PLC-like (P variant) | 0.6709 | Inherited |
| MaoC-like | 0.8215 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.8829 | Inherited |
| Biotin holoenzyme synthetase | 0.9044 | Inherited |
| DmpG/LeuA communication domain-like | 0.9185 | Inherited |
| Caspase recruitment domain, CARD | 0.964 | Inherited |
| cAMP-binding domain | 0.9807 | Inherited |
| CoA-binding domain | 1 | Inherited |
| Branched-chain alpha-keto acid dehydrogenase PP module | 1 | Inherited |
| PP-loop ATPase | 1 | Inherited |
| Dihydrofolate reductases | 1 | Inherited |
| Ribonuclease H | 1 | Inherited |
| ALDH-like | 1 | Inherited |
| Elongation factors | 1 | Inherited |
| Acetyl-CoA synthetase-like | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| Succinyl-CoA synthetase, beta-chain, N-terminal domain | 1 | Inherited |
| Biotin biosynthesis protein BioH | 1 | Inherited |
| Dual specificity phosphatase-like | 1 | Inherited |
| Ribonuclease Rh-like | 1 | Inherited |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 1 | Inherited |
| PurM N-terminal domain-like | 1 | Inherited |
| Serine carboxypeptidase-like | 1 | Inherited |
| Class I aldolase | 1 | Inherited |
| DNase I-like | 1 | Inherited |
| PUA domain | 1 | Inherited |
| Class I glutamine amidotransferases (GAT) | 1 | Inherited |
| Globins | 1 | Inherited |
| Dehydroquinate synthase, DHQS | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
| mono-SIS domain | 1 | Inherited |
| Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain | 1 | Inherited |
| UDP-N-acetylglucosamine 2-epimerase | 1 | Inherited |
| DNA ligase | 1 | Inherited |
| BC C-terminal domain-like | 1 | Inherited |
| PurM C-terminal domain-like | 1 | Inherited |
| FMN-linked oxidoreductases | 1 | Inherited |
| Glutamine synthetase, N-terminal domain | 1 | Inherited |
| Tyrosine-dependent oxidoreductases | 1 | Inherited |
| ADC synthase | 1 | Inherited |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 1 | Inherited |
| Aminoacid dehydrogenase-like, C-terminal domain | 1 | Inherited |
| RecA protein-like (ATPase-domain) | 1 | Inherited |
| Trehalose-phosphatase | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| G proteins | 1 | Inherited |
| beta-Lactamase/D-ala carboxypeptidase | 1 | Inherited |
| Alcohol dehydrogenase-like, C-terminal domain | 1 | Inherited |
| Crotonase-like | 1 | Inherited |
| Achaeal helicase C-terminal domain | 1 | Inherited |
| FAD-linked oxidases, N-terminal domain | 1 | Inherited |
| MutT-like | 1 | Inherited |
| Cyclophilin (peptidylprolyl isomerase) | 1 | Inherited |
| BC N-terminal domain-like | 1 | Inherited |
| CheY-related | 1 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Uroporphyrinogen decarboxylase, UROD | 1 | Inherited |
| Branched-chain alpha-keto acid dehydrogenase Pyr module | 1 | Inherited |
| IpsF-like | 1 | Inherited |
| Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) | 1 | Inherited |
| HpcH/HpaI aldolase | 1 | Inherited |
| Alcohol dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Succinyl-CoA synthetase domains | 1 | Inherited |
| CBS-domain pair | 1 | Inherited |
| Nitrogenase iron protein-like | 1 | Inherited |
| Anticodon-binding domain | 1 | Inherited |
| PA domain | 1 | Inherited |
| Glutamine synthetase catalytic domain | 1 | Inherited |
| MoCo biosynthesis proteins | 1 | Inherited |
| Decarboxylase | 1 | Inherited |
| dUTPase-like | 1 | Inherited |
| Extended AAA-ATPase domain | 1 | Inherited |
| BC ATP-binding domain-like | 1 | Inherited |
| Phosphoglucomutase, first 3 domains | 1 | Inherited |
| Shikimate dehydrogenase-like | 1 | Inherited |
| D-aminoacid oxidase-like | 1 | Inherited |
| Kringle modules | 1 | Inherited |
| DHN aldolase/epimerase | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this EC term (Not in SPEC)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0 | DIRECT |
| Citrate synthase | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
| Thiamin pyrophosphokinase, catalytic domain | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Retrovirus capsid dimerization domain-like | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| DNA polymerase III chi subunit | 0 | DIRECT |
| CoA-transferase family III (CaiB/BaiF) | 0 | DIRECT |
| PTS system fructose IIA component-like | 0 | DIRECT |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | DIRECT |
| PLP-dependent transferases | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| Pentapeptide repeat-like | 0 | DIRECT |
| AF1531-like | 0 | DIRECT |
| Tetrapyrrole methylase | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| ClpS-like | 0 | DIRECT |
| PHP14-like | 0 | DIRECT |
| PABC (PABP) domain | 0 | DIRECT |
| Methionine synthase activation domain-like | 0 | DIRECT |
| SAM/Pointed domain | 0 | DIRECT |
| Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
| Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | DIRECT |
| alpha-D-mannose-specific plant lectins | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| SWIB/MDM2 domain | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Trimerization domain of TRAF | 0 | DIRECT |
| Immunoglobulin | 0 | DIRECT |
| Docking domain B of the erythromycin polyketide synthase (DEBS) | 0 | DIRECT |
| Folate-binding domain | 0 | DIRECT |
| Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| MoeA N-terminal region -like | 0 | DIRECT |
| Poly A polymerase C-terminal region-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| Siroheme synthase middle domains-like | 0 | DIRECT |
| QueA-like | 0 | DIRECT |
| RPB5-like RNA polymerase subunit | 0 | DIRECT |
| Radical SAM enzymes | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| CHY zinc finger-like | 0 | DIRECT |
| Sporulation response regulatory protein Spo0B | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| YojJ-like | 0 | DIRECT |
| alpha/beta knot | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Pyridoxine 5'-phosphate synthase | 0 | DIRECT |
| ApbE-like | 0 | DIRECT |
| BAR/IMD domain-like | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | DIRECT |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| RNA polymerase subunits | 0 | DIRECT |
| Formyltransferase | 0 | DIRECT |
| E set domains | 0 | DIRECT |
| tRNA-guanine transglycosylase | 0 | DIRECT |
| Mib/herc2 domain-like | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| CofD-like | 0 | DIRECT |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | DIRECT |
| Phosphohistidine domain | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| DAK1/DegV-like | 0 | DIRECT |
| FAT domain of focal adhesion kinase | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Carbamate kinase-like | 0 | DIRECT |
| RING/U-box | 0 | DIRECT |
| ThiG-like | 0 | DIRECT |
| Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
| LanC-like | 0 | DIRECT |
| Protein kinase-like (PK-like) | 0 | DIRECT |
| Periplasmic binding protein-like II | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| Prenyltransferase-like | 0 | DIRECT |
| YgbK-like | 0 | DIRECT |
| Zinc hairpin stack | 0 | DIRECT |
| Poly(A) polymerase catalytic subunit-like | 0 | DIRECT |
| OMPA-like | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| GlnB-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Pre-PUA domain | 0 | DIRECT |
| Cobalamin adenosyltransferase-like | 0 | DIRECT |
| Malate synthase G | 0 | DIRECT |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Leucine zipper domain | 0 | DIRECT |
| NusB-like | 0 | DIRECT |
| WGR domain-like | 0 | DIRECT |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | DIRECT |
| DhaL-like | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| GST C-terminal domain-like | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| ADP-ribosylation | 0 | DIRECT |
| Nuclear receptor coactivator interlocking domain | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Glucose permease domain IIB | 0 | DIRECT |
| Trm112p-like | 0 | DIRECT |
| RNA polymerase subunit RPB10 | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| CheY-binding domain of CheA | 0 | DIRECT |
| Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
| WWE domain | 0 | DIRECT |
| Transglutaminase, two C-terminal domains | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Kix domain of CBP (creb binding protein) | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Riboflavin kinase-like | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
| Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
| Thiamin phosphate synthase | 0 | DIRECT |
| Monomethylamine methyltransferase MtmB | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| N-terminal domain of cbl (N-cbl) | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| Molybdopterin synthase subunit MoaE | 0 | DIRECT |
| SET domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | DIRECT |
| Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | DIRECT |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
| Retroviral matrix proteins | 0 | DIRECT |
| Purine and uridine phosphorylases | 0 | DIRECT |
| RCC1/BLIP-II | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| NRDP1 C-terminal domain-like | 0 | DIRECT |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | DIRECT |
| EPT/RTPC-like | 0 | DIRECT |
| Insert subdomain of RNA polymerase alpha subunit | 0 | DIRECT |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | DIRECT |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
| DHS-like NAD/FAD-binding domain | 0 | DIRECT |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | DIRECT |
| ARM repeat | 0 | DIRECT |
| TAF(II)230 TBP-binding fragment | 0 | DIRECT |
| PRTase-like | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| DmpA/ArgJ-like | 0 | DIRECT |
| Cyclin-like | 0 | DIRECT |
| Phosphoglycerate kinase | 0 | DIRECT |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| Ankyrin repeat | 0 | DIRECT |
| RPB6/omega subunit-like | 0 | DIRECT |
| THUMP domain-like | 0 | DIRECT |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
| PsbU/PolX domain-like | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Glycerate kinase I | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| TAZ domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 0 | DIRECT |
| MOSC N-terminal domain-like | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| PHP domain-like | 0 | DIRECT |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | DIRECT |
| HPr-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| Methyl-coenzyme M reductase subunits | 0 | DIRECT |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | DIRECT |
| Methionine synthase domain | 0 | DIRECT |
| HAMP domain-like | 0 | DIRECT |
| Protein prenylyltransferase | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
| Homocysteine S-methyltransferase | 0 | DIRECT |
| L domain-like | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| CheW-like | 0 | DIRECT |
| Thymidylate synthase-complementing protein Thy1 | 0 | DIRECT |
| NadA-like | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| Undecaprenyl diphosphate synthase | 0 | DIRECT |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
| PK C-terminal domain-like | 0 | DIRECT |
| Lumazine synthase | 0 | DIRECT |
| TTHA0583/YokD-like | 0 | DIRECT |
| Aspartate/ornithine carbamoyltransferase | 0 | DIRECT |
| PTS system IIB component-like | 0 | DIRECT |
| SSo0622-like | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| PPK N-terminal domain-like | 0 | DIRECT |
| S-adenosylmethionine synthetase | 0 | DIRECT |
| PTS IIb component | 0 | DIRECT |
| Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
| UBC-like | 0 | DIRECT |
| CoA-dependent acyltransferases | 0 | DIRECT |
| PilZ domain-like | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| TK C-terminal domain-like | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| AFP III-like domain | 0 | DIRECT |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Thiolase-like | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| CCHHC domain | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| CbiD-like | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| FMT C-terminal domain-like | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | DIRECT |
| Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
| MoeA C-terminal domain-like | 0 | DIRECT |
| PH domain-like | 0.000000000000001936 | DIRECT |
| Fic-like | 0.000000000000004899 | DIRECT |
| Sensory domain-like | 0.00000000000003457 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0.0000000000001074 | DIRECT |
| TRAF domain-like | 0.0000000000003728 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0.000000000000477 | DIRECT |
| Molybdenum cofactor biosynthesis proteins | 0.0000000000004816 | DIRECT |
| RNI-like | 0.000000000001328 | DIRECT |
| FYVE/PHD zinc finger | 0.000000000006992 | DIRECT |
| Bromodomain | 0.000000000009154 | DIRECT |
| beta-beta-alpha zinc fingers | 0.00000000001206 | DIRECT |
| L30e-like | 0.00000000002283 | DIRECT |
| CCCH zinc finger | 0.00000000005556 | DIRECT |
| Homeodomain-like | 0.00000000008468 | DIRECT |
| Ricin B-like lectins | 0.0000000004246 | DIRECT |
| ClpP/crotonase | 0.0000000005885 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0.000000001918 | DIRECT |
| Phospholipase D/nuclease | 0.000000003911 | DIRECT |
| WW domain | 0.000000004169 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0.00000008581 | DIRECT |
| Single hybrid motif | 0.0000001291 | DIRECT |
| HprK N-terminal domain-like | 0.0000001376 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.0000001551 | DIRECT |
| Chromo domain-like | 0.000000728 | DIRECT |
| post-AAA+ oligomerization domain-like | 0.0000007907 | DIRECT |
| Ubiquitin-like | 0.00000213 | DIRECT |
| WD40 repeat-like | 0.0000058 | DIRECT |
| NHL repeat | 0.00001035 | DIRECT |
| PIN domain-like | 0.00001487 | DIRECT |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.00005404 | DIRECT |
| Second domain of FERM | 0.00006572 | DIRECT |
| GckA/TtuD-like | 0.00008149 | DIRECT |
| Glycosyl hydrolase domain | 0.000124 | DIRECT |
| ACP-like | 0.0001254 | DIRECT |
| TPR-like | 0.0002271 | DIRECT |
| SMAD/FHA domain | 0.0002389 | DIRECT |
| GAF domain-like | 0.0003524 | DIRECT |
| EF-hand | 0.0004953 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0.0008354 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0.001017 | INHERITED FROM: Protein-serine/threonine kinases || Transferring phosphorus-containing groups |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.001254 | INHERITED FROM: Glutamate formimidoyltransferase || Transferring one-carbon groups || Hydroxymethyl-, formyl- and related transferases |
| Duplicated hybrid motif | 0.001348 | INHERITED FROM: Protein-N(pi)-phosphohistidine--D-glucose phosphotransferase || phosphotransferase || Phosphotransferases with an alcohol group as acceptor || Transferring phosphorus-containing groups |
| Replicase NSP9 | 0.006099 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Coronavirus NSP8-like | 0.006099 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Coronavirus NSP10-like | 0.006099 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| Coronavirus NSP7-like | 0.006099 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| YWTD domain | 0.006582 | INHERITED FROM: Protein-tyrosine kinases || Receptor protein-tyrosine kinase || Transferring phosphorus-containing groups |
| Ran binding protein zinc finger-like | 0.007452 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || RBR-type E3 ubiquitin transferase |
| PX domain | 0.007538 | INHERITED FROM: Phosphatidylinositol-4-phosphate 3-kinase || Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorus-containing groups |
| HMG-box | 0.008695 | INHERITED FROM: Transferring one-carbon groups || [Histone H3]-lysine(4) N-trimethyltransferase || Methyltransferases |
| MFS general substrate transporter | 0.008695 | INHERITED FROM: Spermidine synthase || Transferring alkyl or aryl groups, other than methyl groups |
| CRAL/TRIO domain | 0.009161 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorus-containing groups |
| FabD/lysophospholipase-like | 0.01326 | INHERITED FROM: Fatty-acyl-CoA synthase system || Fatty-acid synthase system || [Acyl-carrier-protein] S-acetyltransferase || [Acyl-carrier-protein] S-malonyltransferase || Transferring groups other than amino-acyl groups || 6-methylsalicylic acid synthase || 10-deoxymethynolide syntase || Acyltransferases || Beta-ketoacyl-[acyl-carrier-protein] synthase I || 6-deoxyerythronolide-B synthase || Lovastatin nonaketide synthase || 2-methylbutanoate polyketide synthase || Narbonolide synthase |
| RNA-binding domain, RBD | 0.01888 | INHERITED FROM: tRNA (carboxymethyluridine(34)-5-O)-methyltransferase || Polynucleotide adenylyltransferase || RNA uridylyltransferase || Transferring one-carbon groups || [Histone H3]-lysine(4) N-trimethyltransferase || Methyltransferases || RING-type E3 ubiquitin transferase |
| SAP domain | 0.01937 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || NAD(+) ADP-ribosyltransferase || RING-type E3 ubiquitin transferase |
| Galactose oxidase, central domain | 0.02378 | INHERITED FROM: tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase || Transferring groups other than amino-acyl groups || Transferring one-carbon groups || Acyltransferases || methoxycarbonyltransferase || Methyltransferases || Guanylate kinase || Phosphotransferases with a phosphate group as acceptor |
| GroEL apical domain-like | 0.02417 | INHERITED FROM: 1-phosphatidylinositol-3-phosphate 5-kinase || Phosphotransferases with an alcohol group as acceptor || Transferring phosphorus-containing groups |
| Outer arm dynein light chain 1 | 0.03518 | INHERITED FROM: Protein geranylgeranyltransferase type II || Transferring alkyl or aryl groups, other than methyl groups |
| ACT-like | 0.03531 | INHERITED FROM: GTP diphosphokinase || Transferring aldehyde or ketonic groups || Aspartate kinase || Nucleotidyltransferases || Diphosphotransferases || [Protein-PII] uridylyltransferase || Acetolactate synthase || Phosphotransferases with a carboxy group as acceptor || Transferring phosphorus-containing groups |
| NSP3A-like | 0.04304 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
| SCP-like | 0.04394 | INHERITED FROM: Transferring groups other than amino-acyl groups || Propanoyl-CoA C-acyltransferase || Acyltransferases |
| Acid proteases | 0.05354 | INHERITED FROM: RNA-directed DNA polymerase || Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorus-containing groups |
| PA domain | 0.0803 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || RING-type E3 ubiquitin transferase |
| YrdC/RibB | 0.09132 | INHERITED FROM: Nucleotidyltransferases || L-threonylcarbamoyladenylate synthase || Transferring phosphorus-containing groups |
| DEATH domain | 0.1162 | INHERITED FROM: Protein-tyrosine kinases || Aminoacyltransferases || Non-specific protein-tyrosine kinase || Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || RING-type E3 ubiquitin transferase || Transferring phosphorus-containing groups |
| SARS Nsp1-like | 0.154 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases |
| Tropomyosin | 0.1641 | INHERITED FROM: Acyltransferases |
| Chaperone J-domain | 0.1641 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
| Cell wall binding repeat | 0.1951 | INHERITED FROM: Dextransucrase || Glycosyltransferases || Hexosyltransferases |
| Trypsin-like serine proteases | 0.2291 | INHERITED FROM: RNA-directed RNA polymerase || mRNA (guanine-N(7)-)-methyltransferase || Nucleotidyltransferases || Methyltransferase cap1 || Transferring phosphorus-containing groups |
| GTPase activation domain, GAP | 0.2399 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
| Formin homology 2 domain (FH2 domain) | 0.24 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || RING-type E3 ubiquitin transferase |
| Quinoprotein alcohol dehydrogenase-like | 0.2488 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorus-containing groups |
| UBA-like | 0.2836 | INHERITED FROM: HECT-type E3 ubiquitin transferase || Aminoacyltransferases || Acyltransferases || Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
| Hedgehog/intein (Hint) domain | 0.2973 | INHERITED FROM: Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorus-containing groups |
| Terpenoid synthases | 0.3087 | INHERITED FROM: Squalene synthase || Geranylfarnesyl diphosphate synthase || (2E,6E)-farnesyl diphosphate synthase || 4,4'-diapophytoene synthase || All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) || specific) || 15-cis-phytoene synthase || Geranylgeranyl diphosphate synthase || Presqualene diphosphate synthase || Transferring alkyl or aryl groups, other than methyl groups || All-trans-decaprenyl-diphosphate synthase || Dimethylallyltranstransferase |
| MIT domain | 0.3462 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorus-containing groups |
| MAPEG domain-like | 0.347 | INHERITED FROM: Glutathione transferase || Transferring alkyl or aryl groups, other than methyl groups |
| C-terminal domain of transcriptional repressors | 0.3814 | INHERITED FROM: Pantothenate kinase || Phosphotransferases with an alcohol group as acceptor |
| C-type lectin-like | 0.4585 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
| GroEL-intermediate domain like | 0.4931 | INHERITED FROM: 1-phosphatidylinositol-3-phosphate 5-kinase || Phosphotransferases with an alcohol group as acceptor |
| Homing endonucleases | 0.5023 | INHERITED FROM: Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorus-containing groups |
| Multidrug efflux transporter AcrB transmembrane domain | 0.5305 | INHERITED FROM: Heme o synthase || Transferring alkyl or aryl groups, other than methyl groups |
| Concanavalin A-like lectins/glucanases | 0.5347 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || Non-specific serine/threonine protein kinase || Glycosyltransferases || Protein-serine/threonine kinases || Hexosyltransferases || Xyloglucan:xyloglucosyl transferase || RING-type E3 ubiquitin transferase |
| HCP-like | 0.6215 | INHERITED FROM: [Elongation factor 2] kinase || Protein-serine/threonine kinases |
| Rubredoxin-like | 0.6406 | INHERITED FROM: Adenylate kinase || Phosphotransferases with a phosphate group as acceptor |
| Carbon-nitrogen hydrolase | 0.6954 | INHERITED FROM: Transferring groups other than amino-acyl groups || Acyltransferases || Apolipoprotein N-acyltransferase |
| UROD/MetE-like | 0.7699 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase || methyltransferase |
| Cobalamin (vitamin B12)-binding domain | 0.7862 | INHERITED FROM: Transferring one-carbon groups || Methionine synthase || Methyltransferases |
| Tudor/PWWP/MBT | 0.8839 | INHERITED FROM: HECT-type E3 ubiquitin transferase || DNA (cytosine-5-)-methyltransferase |
| NTF2-like | 0.9039 | INHERITED FROM: Calcium/calmodulin-dependent protein kinase || Protein-serine/threonine kinases || Transferring phosphorus-containing groups |
| Starch-binding domain-like | 0.9703 | INHERITED FROM: Cyclomaltodextrin glucanotransferase || Glycosyltransferases || Hexosyltransferases |
| Galactose-binding domain-like | 1 | INHERITED FROM: Protein-tyrosine kinases || HECT-type E3 ubiquitin transferase || Receptor protein-tyrosine kinase |
| Lysozyme-like | 1 | INHERITED FROM: Peptidoglycan glycosyltransferase || Glycosyltransferases || Hexosyltransferases |
| BRCT domain | 1 | INHERITED FROM: DNA nucleotidylexotransferase || NAD(+) ADP-ribosyltransferase || RING-type E3 ubiquitin transferase |
| Adenine nucleotide alpha hydrolases-like | 1 | INHERITED FROM: Sulfate adenylyltransferase || FAD synthase || tRNA-uridine 2-sulfurtransferase || Transferring sulfur-containing groups || tRNA uracil 4-sulfurtransferase || Sulfurtransferases || tRNA-5-taurinomethyluridine 2-sulfurtransferase |
| "Winged helix" DNA-binding domain | 1 | INHERITED FROM: Histone acetyltransferase || CTP-dependent riboflavin kinase || (RS)-norcoclaurine 6-O-methyltransferase || Isoflavone 4'-O-methyltransferase || 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase || Acetylserotonin O-methyltransferase || (Iso)eugenol O-methyltransferase || Methyltransferases || Isoflavone 7-O-methyltransferase || Caffeate O-methyltransferase || (S)-scoulerine 9-O-methyltransferase || 1-phosphatidylinositol-3-phosphate 5-kinase || Flavone 3'-O-methyltransferase || 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase || 6-hydroxytryprostatin B O-methyltransferase |
| PreATP-grasp domain | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase || Aspartate carbamoyltransferase |
| Ribonuclease H-like | 1 | INHERITED FROM: RNA-directed DNA polymerase || Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorus-containing groups |
| RmlC-like cupins | 1 | INHERITED FROM: Pyrimidine-nucleoside phosphorylase || Mannose-1-phosphate guanylyltransferase || Pentosyltransferases || Thymidine phosphorylase || Glycosyltransferases || Uridine phosphorylase || Guanosine phosphorylase |
| Dehydroquinate synthase-like | 1 | INHERITED FROM: Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase || Transferring alkyl or aryl groups, other than methyl groups || Phosphotransferases with an alcohol group as acceptor |
| Cyclophilin-like | 1 | INHERITED FROM: Aminoacyltransferases || RING-type E3 ubiquitin transferase |
| (Phosphotyrosine protein) phosphatases II | 1 | INHERITED FROM: mRNA guanylyltransferase |
| Glycoside hydrolase/deacetylase | 1 | INHERITED FROM: Transferring other glycosyl groups || Beta-galactoside alpha-(2,6)-sialyltransferase |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | INHERITED FROM: tRNA (guanine(37)-N(1))-methyltransferase || 6-phosphofructokinase |
| NagB/RpiA/CoA transferase-like | 1 | INHERITED FROM: 3-oxoacid CoA-transferase || Transferring sulfur-containing groups || CoA-transferases |
| Thioredoxin-like | 1 | INHERITED FROM: Glutathione transferase || Transferring alkyl or aryl groups, other than methyl groups || Protein-histidine kinases |
| Heme oxygenase-like | 1 | INHERITED FROM: Phosphooxymethylpyrimidine kinase || Hydroxymethylpyrimidine kinase |
| Sec63 N-terminal domain-like | 1 | INHERITED FROM: DNA-directed DNA polymerase |
| Nucleotide cyclase | 1 | INHERITED FROM: Diguanylate cyclase || Nucleotidyltransferases |
| Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: Inositol-hexakisphosphate kinase || Phosphoribosylglycinamide formyltransferase || ATP citrate synthase || Phosphotransferases with paired acceptors || Diphosphoinositol-pentakisphosphate kinase || Inositol-1,3,4-trisphosphate 5/6-kinase || Pyruvate, phosphate dikinase || Inositol-tetrakisphosphate 1-kinase || Pyruvate, water dikinase |
| Nucleotide-binding domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase || Methyltransferases |
| Kelch motif | 1 | INHERITED FROM: tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase || Transferring groups other than amino-acyl groups || methoxycarbonyltransferase || Methyltransferases |
| SGNH hydrolase | 1 | INHERITED FROM: Diglucosylglycerate octanoyltransferase || N-acylneuraminate cytidylyltransferase |
| Dihydrofolate reductase-like | 1 | INHERITED FROM: Transferring one-carbon groups || Methyltransferases || Thymidylate synthase |
| Dimeric alpha+beta barrel | 1 | INHERITED FROM: Homocitrate synthase || Acyl groups converted into alkyl groups on transfer |
| PheT/TilS domain | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
| Rudiment single hybrid motif | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
| TGS-like | 1 | INHERITED FROM: GTP diphosphokinase || Diphosphotransferases |
| FMN-linked oxidoreductases | 1 | INHERITED FROM: [Acyl-carrier-protein] S-malonyltransferase || Heptaprenylglyceryl phosphate synthase || Phosphoglycerol geranylgeranyltransferase || Transferring alkyl or aryl groups, other than methyl groups |
| Inosine monophosphate dehydrogenase (IMPDH) | 1 | INHERITED FROM: Fatty-acyl-CoA synthase system || [Acyl-carrier-protein] S-acetyltransferase || [Acyl-carrier-protein] S-malonyltransferase |
| Phosphoglycerate mutase-like | 1 | INHERITED FROM: Inositol-hexakisphosphate kinase || Diphosphoinositol-pentakisphosphate kinase || 6-phosphofructo-2-kinase |
| Six-hairpin glycosidases | 1 | INHERITED FROM: 4-alpha-glucanotransferase || Kojibiose phosphorylase || Hexosyltransferases |
| Zn-dependent exopeptidases | 1 | INHERITED FROM: Glutaminyl-peptide cyclotransferase |
| tRNA-binding arm | 1 | INHERITED FROM: glycyltransferase |
| Kringle-like | 1 | INHERITED FROM: Protein-tyrosine kinases || Receptor protein-tyrosine kinase |
| CheY-like | 1 | INHERITED FROM: Protein-histidine kinases || Transferring phosphorus-containing groups |
| Terpenoid cyclases/Protein prenyltransferases | 1 | INHERITED FROM: Protein geranylgeranyltransferase type I || Protein farnesyltransferase || Protein geranylgeranyltransferase type II || Transferring alkyl or aryl groups, other than methyl groups |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | INHERITED FROM: Glutamine--fructose-6-phosphate transaminase (isomerizing) || Aminoacyltransferases || Amidophosphoribosyltransferase || Gamma-glutamyltransferase || Transaminases || Transferring nitrogenous groups |
| DNase I-like | 1 | INHERITED FROM: RNA-directed DNA polymerase |
| lambda repressor-like DNA-binding domains | 1 | INHERITED FROM: Ribosylnicotinamide kinase || Nicotinamide-nucleotide adenylyltransferase || DNA (cytosine-5-)-methyltransferase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Aspartate carbamoyltransferase || Carboxy- and carbamoyltransferases |
| Glutamine synthetase, N-terminal domain | 1 | INHERITED FROM: Protein S-acyltransferase |
| Glutamine synthetase/guanido kinase | 1 | INHERITED FROM: Phosphotransferases with a nitrogenous group as acceptor || Protein-arginine kinases || Protein S-acyltransferase || Arginine kinase || Creatine kinase || Transferring phosphorus-containing groups |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 1 | INHERITED FROM: Nicotinamide phosphoribosyltransferase || Nicotinate-nucleotide diphosphorylase (carboxylating) || Pentosyltransferases || Glycosyltransferases |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: Fatty-acid synthase system || [Acyl-carrier-protein] S-acetyltransferase || Transferring groups other than amino-acyl groups || Phospholipid:diacylglycerol acyltransferase || Bile acid-CoA:amino acid N-acyltransferase || Diacylglycerol O-acyltransferase || Acyltransferases || Phosphatidylcholine--sterol O-acyltransferase || Trehalose O-mycolyltransferase || Sinapoylglucose--sinapoylglucose O-sinapoyltransferase || Ethanol O-acetyltransferase || Homoserine O-acetyltransferase || Homoserine O-succinyltransferase || Malonyl-[acyl-carrier protein] O-methyltransferase |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: mRNA guanylyltransferase || mRNA (guanine-N(7)-)-methyltransferase |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Fatty-acyl-CoA synthase system || Fatty-acid synthase system || Uroporphyrinogen-III C-methyltransferase || [Acyl-carrier-protein] S-acetyltransferase || ATP citrate synthase || Aspartate kinase || 6-methylsalicylic acid synthase || 10-deoxymethynolide syntase || Shikimate kinase || Beta-ketoacyl-[acyl-carrier-protein] synthase I || 6-deoxyerythronolide-B synthase || 3-phosphoshikimate 1-carboxyvinyltransferase || Lovastatin nonaketide synthase || UDP-4-amino-4-deoxy-L-arabinose formyltransferase || 2-methylbutanoate polyketide synthase || Narbonolide synthase |
| IpsF-like | 1 | INHERITED FROM: Nucleotidyltransferases || 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase || Transferring phosphorus-containing groups |
| SIS domain | 1 | INHERITED FROM: Glutamine--fructose-6-phosphate transaminase (isomerizing) || Glucokinase || Transaminases || Transferring nitrogenous groups |
| Ribonuclease Rh-like | 1 | INHERITED FROM: RNA-directed RNA polymerase |
| Nudix | 1 | INHERITED FROM: ADP-D-ribose pyrophosphorylase |
| P-loop containing nucleoside triphosphate hydrolases | 1 | INHERITED FROM: Nicotinate riboside kinase || Sulfate adenylyltransferase || Uridine kinase || RNA-directed RNA polymerase || Polynucleotide adenylyltransferase || Sulfotransferases || Phosphoribulokinase || dTMP kinase || Adenosylcobinamide-phosphate guanylyltransferase || (d)CMP kinase || mRNA (guanine-N(7)-)-methyltransferase || Adenylate dimethylallyltransferase (ADP/ATP-dependent) || Dephospho-CoA kinase || Adenylate kinase || tRNA(Met) cytidine acetyltransferase || Shikimate kinase || Polynucleotide 5'-hydroxyl-kinase || Gluconokinase || Adenylate dimethylallyltransferase (AMP-dependent) || Ribosylnicotinamide kinase || 6-phosphofructo-2-kinase || Guanylate kinase || Adenylyl-sulfate kinase || Transferring alkyl or aryl groups, other than methyl groups || tRNA dimethylallyltransferase || Phosphate acetyltransferase || Tetraacyldisaccharide 4'-kinase || Phosphotransferases with an alcohol group as acceptor || Phosphotransferases with a phosphate group as acceptor || Deoxycytidine kinase || Methyltransferase cap1 || [Pyruvate, phosphate dikinase] kinase || Thymidine kinase || Transferring phosphorus-containing groups |
| beta-lactamase/transpeptidase-like | 1 | INHERITED FROM: Peptidoglycan glycosyltransferase || Glycosyltransferases || Hexosyltransferases |
| HIT-like | 1 | INHERITED FROM: Sulfate adenylyltransferase (ADP) || Nucleotidyltransferases || ATP adenylyltransferase || UDP-glucose--hexose-1-phosphate uridylyltransferase |
| ADC-like | 1 | INHERITED FROM: AMP phosphorylase |
| post-HMGL domain-like | 1 | INHERITED FROM: Acyltransferases || 2-isopropylmalate synthase || Acyl groups converted into alkyl groups on transfer |
| Families 57/38 glycoside transferase middle domain | 1 | INHERITED FROM: 1,4-alpha-glucan branching enzyme || Hexosyltransferases |
| Pentein | 1 | INHERITED FROM: Amidinotransferases |
| Galactose mutarotase-like | 1 | INHERITED FROM: Kojibiose phosphorylase || Hexosyltransferases |
| Nucleotidylyl transferase | 1 | INHERITED FROM: Sulfate adenylyltransferase || D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase || D-glycero-beta-D-manno-heptose-7-phosphate kinase || Riboflavin kinase || FAD synthase || Ethanolamine-phosphate cytidylyltransferase || Pantetheine-phosphate adenylyltransferase || Glycerol-3-phosphate cytidylyltransferase || Nucleotidyltransferases || Nicotinate-nucleotide adenylyltransferase || Nicotinamide-nucleotide adenylyltransferase || Choline-phosphate cytidylyltransferase || Transferring phosphorus-containing groups |
| Clavaminate synthase-like | 1 | INHERITED FROM: tRNA (carboxymethyluridine(34)-5-O)-methyltransferase || RNA-directed RNA polymerase || tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase || methoxycarbonyltransferase |
| cAMP-binding domain-like | 1 | INHERITED FROM: Protein-serine/threonine kinases || cGMP-dependent protein kinase |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | INHERITED FROM: NAD(+) ADP-ribosyltransferase || Phosphotransferases with an alcohol group as acceptor || Thymidine kinase || Transferring phosphorus-containing groups |
| MesJ substrate recognition domain-like | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
| Dihydropteroate synthetase-like | 1 | INHERITED FROM: Transferring one-carbon groups || Diphosphotransferases || Methionine synthase || Tetrahydromethanopterin S-methyltransferase || Methyltransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase || Transferring alkyl or aryl groups, other than methyl groups || Co-methyltransferase || Dihydropteroate synthase |
| Cysteine proteinases | 1 | INHERITED FROM: RNA-directed RNA polymerase || Glutathione gamma-glutamylcysteinyltransferase || Aminoacyltransferases || Acyltransferases || Protein-glutamine gamma-glutamyltransferase || Arylamine N-acetyltransferase |
| GroES-like | 1 | INHERITED FROM: Fatty-acid synthase system || [Acyl-carrier-protein] S-acetyltransferase || [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-[acyl-carrier-protein] synthase I || 2-methylbutanoate polyketide synthase |
| CYTH-like phosphatases | 1 | INHERITED FROM: mRNA guanylyltransferase || mRNA (guanine-N(7)-)-methyltransferase || Methyltransferases |
| PurM C-terminal domain-like | 1 | INHERITED FROM: Selenide, water dikinase || Phosphoribosylglycinamide formyltransferase || Phosphotransferases with paired acceptors || Thiamine-phosphate kinase |
| Class II aaRS and biotin synthetases | 1 | INHERITED FROM: Octanoyl-[GcvH]:protein N-octanoyltransferase || Transferring groups other than amino-acyl groups || Lysyltransferase || Acyltransferases || Lipoyl(octanoyl) transferase |
| Cytochrome c | 1 | INHERITED FROM: Thiosulfotransferases || Transferring sulfur-containing groups |
| SAICAR synthase-like | 1 | INHERITED FROM: 1-phosphatidylinositol-4-phosphate 5-kinase || Inositol-hexakisphosphate kinase || Inositol-polyphosphate multikinase || Phosphatidylinositol-4,5-bisphosphate 3-kinase || Inositol-tetrakisphosphate 5-kinase || 1-phosphatidylinositol-5-phosphate 4-kinase || 1-phosphatidylinositol-3-phosphate 5-kinase || Phosphotransferases with an alcohol group as acceptor || Inositol-trisphosphate 3-kinase |
| PurM N-terminal domain-like | 1 | INHERITED FROM: Selenide, water dikinase || Phosphoribosylglycinamide formyltransferase || Phosphotransferases with paired acceptors || Thiamine-phosphate kinase |
| HD-domain/PDEase-like | 1 | INHERITED FROM: GTP diphosphokinase || Nucleotidyltransferases || Diphosphotransferases || tRNA (cytidine(56)-2'-O)-methyltransferase || [Protein-PII] uridylyltransferase || Transferring phosphorus-containing groups |
| FAD-binding/transporter-associated domain-like | 1 | INHERITED FROM: Alkylglycerone-phosphate synthase |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: mRNA guanylyltransferase || 23S rRNA (uracil(1939)-C(5))-methyltransferase || Lysyltransferase || Nucleotidyltransferases || Polyribonucleotide nucleotidyltransferase |
| Translation proteins | 1 | INHERITED FROM: Sulfate adenylyltransferase || Nucleotidyltransferases || Adenylyl-sulfate kinase |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | INHERITED FROM: Fatty-acyl-CoA synthase system || [Acyl-carrier-protein] S-acetyltransferase || [Acyl-carrier-protein] S-malonyltransferase |
| Riboflavin synthase domain-like | 1 | INHERITED FROM: Riboflavin synthase |
| Macro domain-like | 1 | INHERITED FROM: RNA-directed RNA polymerase || Polynucleotide adenylyltransferase || Nucleotidyltransferases |
| (Trans)glycosidases | 1 | INHERITED FROM: Galactinol--sucrose galactosyltransferase || 4-alpha-glucanotransferase || Alpha-1,3-glucan synthase || Cyclomaltodextrin glucanotransferase || Dextransucrase || Starch synthase (maltosyl-transferring) || Sucrose phosphorylase || 1,4-alpha-glucan branching enzyme || Glycosyltransferases || Glucosylglycerate phosphorylase || Hexosyltransferases |
| FAD-linked oxidases, C-terminal domain | 1 | INHERITED FROM: Alkylglycerone-phosphate synthase || Transferring alkyl or aryl groups, other than methyl groups |
| Prismane protein-like | 1 | INHERITED FROM: CO-methylating acetyl-CoA synthase |
| Globin-like | 1 | INHERITED FROM: Diguanylate cyclase |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: Cysteate synthase || Cysteine synthase || N-(2-amino-2-carboxyethyl)-L-glutamate synthase || Transferring alkyl or aryl groups, other than methyl groups |
| ADC synthase | 1 | INHERITED FROM: Transaminases || Transferring nitrogenous groups || Aminodeoxychorismate synthase |
| Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| HAD-like | 1 | INHERITED FROM: Polynucleotide 5'-hydroxyl-kinase || Alpha,alpha-trehalose-phosphate synthase (UDP-forming) || N-acylneuraminate cytidylyltransferase |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
| dUTPase-like | 1 | INHERITED FROM: RNA-directed DNA polymerase || DNA-directed DNA polymerase |
| Nicotinate/Quinolinate PRTase N-terminal domain-like | 1 | INHERITED FROM: Nicotinate-nucleotide diphosphorylase (carboxylating) || Pentosyltransferases || Glycosyltransferases |
| Zinc beta-ribbon | 1 | INHERITED FROM: Histone acetyltransferase || DNA-directed RNA polymerase |
| Arabinanase/levansucrase/invertase | 1 | INHERITED FROM: Levansucrase || Glycosyltransferases || Hexosyltransferases |
| CBS-domain pair | 1 | INHERITED FROM: Transferring groups other than amino-acyl groups || Acyltransferases || Homoserine O-acetyltransferase |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | INHERITED FROM: Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase || Dihydropteroate synthase |
| FAD-linked reductases, C-terminal domain | 1 | INHERITED FROM: Transferring one-carbon groups || tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase || Methyltransferases |
| Class I glutamine amidotransferase-like | 1 | INHERITED FROM: Transferring groups other than amino-acyl groups || Acyltransferases || Homoserine O-acetyltransferase || Homoserine O-succinyltransferase || 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase || Aminodeoxychorismate synthase |
| PDZ domain-like | 1 | INHERITED FROM: Aminoacyltransferases || Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || RING-type E3 ubiquitin transferase |
| ALDH-like | 1 | INHERITED FROM: Glutamate 5-kinase |
| vWA-like | 1 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || RING-type E3 ubiquitin transferase |
| Acetyl-CoA synthetase-like | 1 | INHERITED FROM: Transferring groups other than amino-acyl groups || Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: Aspartate carbamoyltransferase || Carboxy- and carbamoyltransferases |
| PFL-like glycyl radical enzymes | 1 | INHERITED FROM: Formate C-acetyltransferase || Transferring groups other than amino-acyl groups |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Transferases for other substituted phosphate groups || Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase |
| FAD/NAD(P)-binding domain | 1 | INHERITED FROM: (NAD(P)H-oxidizing) || Sulfide-dependent adenosine diphosphate thiazole synthase || Transferring one-carbon groups || tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase || Pentosyltransferases || Methyltransferases || Cysteine-dependent adenosine diphosphate thiazole synthase |
| Phosphoglucomutase, C-terminal domain | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase |
| RuvA domain 2-like | 1 | INHERITED FROM: Diadenylate cyclase |
| Succinyl-CoA synthetase domains | 1 | INHERITED FROM: ATP citrate synthase || Acyl groups converted into alkyl groups on transfer |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
| Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
| UDP-Glycosyltransferase/glycogen phosphorylase | 0 | Direct |
| Citrate synthase | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
| Thiamin pyrophosphokinase, catalytic domain | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Retrovirus capsid dimerization domain-like | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| SH2 domain | 0 | Direct |
| DNA polymerase III chi subunit | 0 | Direct |
| CoA-transferase family III (CaiB/BaiF) | 0 | Direct |
| PTS system fructose IIA component-like | 0 | Direct |
| Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | Direct |
| PLP-dependent transferases | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| Pentapeptide repeat-like | 0 | Direct |
| AF1531-like | 0 | Direct |
| Tetrapyrrole methylase | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| ClpS-like | 0 | Direct |
| PHP14-like | 0 | Direct |
| PABC (PABP) domain | 0 | Direct |
| Methionine synthase activation domain-like | 0 | Direct |
| SAM/Pointed domain | 0 | Direct |
| Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
| Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | Direct |
| alpha-D-mannose-specific plant lectins | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| SWIB/MDM2 domain | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Trimerization domain of TRAF | 0 | Direct |
| Immunoglobulin | 0 | Direct |
| Docking domain B of the erythromycin polyketide synthase (DEBS) | 0 | Direct |
| Folate-binding domain | 0 | Direct |
| Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| MoeA N-terminal region -like | 0 | Direct |
| Poly A polymerase C-terminal region-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| Siroheme synthase middle domains-like | 0 | Direct |
| QueA-like | 0 | Direct |
| RPB5-like RNA polymerase subunit | 0 | Direct |
| Radical SAM enzymes | 0 | Direct |
| Aldolase | 0 | Direct |
| CHY zinc finger-like | 0 | Direct |
| Sporulation response regulatory protein Spo0B | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| YojJ-like | 0 | Direct |
| alpha/beta knot | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Pyridoxine 5'-phosphate synthase | 0 | Direct |
| ApbE-like | 0 | Direct |
| BAR/IMD domain-like | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
| Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | Direct |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| RNA polymerase subunits | 0 | Direct |
| Formyltransferase | 0 | Direct |
| E set domains | 0 | Direct |
| tRNA-guanine transglycosylase | 0 | Direct |
| Mib/herc2 domain-like | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| CofD-like | 0 | Direct |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | Direct |
| Phosphohistidine domain | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| DAK1/DegV-like | 0 | Direct |
| FAT domain of focal adhesion kinase | 0 | Direct |
| MIR domain | 0 | Direct |
| Carbamate kinase-like | 0 | Direct |
| RING/U-box | 0 | Direct |
| ThiG-like | 0 | Direct |
| Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
| LanC-like | 0 | Direct |
| Protein kinase-like (PK-like) | 0 | Direct |
| Periplasmic binding protein-like II | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| Prenyltransferase-like | 0 | Direct |
| YgbK-like | 0 | Direct |
| Zinc hairpin stack | 0 | Direct |
| Poly(A) polymerase catalytic subunit-like | 0 | Direct |
| OMPA-like | 0 | Direct |
| KA1-like | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| GlnB-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Pre-PUA domain | 0 | Direct |
| Cobalamin adenosyltransferase-like | 0 | Direct |
| Malate synthase G | 0 | Direct |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Leucine zipper domain | 0 | Direct |
| NusB-like | 0 | Direct |
| WGR domain-like | 0 | Direct |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Methylated DNA-protein cysteine methyltransferase domain | 0 | Direct |
| DhaL-like | 0 | Direct |
| EndoU-like | 0 | Direct |
| GST C-terminal domain-like | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| ADP-ribosylation | 0 | Direct |
| Nuclear receptor coactivator interlocking domain | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Glucose permease domain IIB | 0 | Direct |
| Trm112p-like | 0 | Direct |
| RNA polymerase subunit RPB10 | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| CheY-binding domain of CheA | 0 | Direct |
| Putative methyltransferase TM0872, insert domain | 0 | Direct |
| WWE domain | 0 | Direct |
| Transglutaminase, two C-terminal domains | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Kix domain of CBP (creb binding protein) | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Riboflavin kinase-like | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| Plexin repeat | 0 | Direct |
| C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
| Domain of poly(ADP-ribose) polymerase | 0 | Direct |
| Thiamin phosphate synthase | 0 | Direct |
| Monomethylamine methyltransferase MtmB | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| N-terminal domain of cbl (N-cbl) | 0 | Direct |
| PUA domain-like | 0 | Direct |
| Molybdopterin synthase subunit MoaE | 0 | Direct |
| SET domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | Direct |
| Rhodanese/Cell cycle control phosphatase | 0 | Direct |
| Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | Direct |
| Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
| Retroviral matrix proteins | 0 | Direct |
| Purine and uridine phosphorylases | 0 | Direct |
| RCC1/BLIP-II | 0 | Direct |
| SH3-domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| NRDP1 C-terminal domain-like | 0 | Direct |
| Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | Direct |
| EPT/RTPC-like | 0 | Direct |
| Insert subdomain of RNA polymerase alpha subunit | 0 | Direct |
| D-aminoacid aminotransferase-like PLP-dependent enzymes | 0 | Direct |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | Direct |
| DHS-like NAD/FAD-binding domain | 0 | Direct |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | Direct |
| ARM repeat | 0 | Direct |
| TAF(II)230 TBP-binding fragment | 0 | Direct |
| PRTase-like | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| DmpA/ArgJ-like | 0 | Direct |
| Cyclin-like | 0 | Direct |
| Phosphoglycerate kinase | 0 | Direct |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| Ankyrin repeat | 0 | Direct |
| RPB6/omega subunit-like | 0 | Direct |
| THUMP domain-like | 0 | Direct |
| Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
| PsbU/PolX domain-like | 0 | Direct |
| Sema domain | 0 | Direct |
| Glycerate kinase I | 0 | Direct |
| L27 domain | 0 | Direct |
| TAZ domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 0 | Direct |
| MOSC N-terminal domain-like | 0 | Direct |
| Polo-box domain | 0 | Direct |
| PHP domain-like | 0 | Direct |
| Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) | 0 | Direct |
| HPr-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| Methyl-coenzyme M reductase subunits | 0 | Direct |
| 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | Direct |
| Methionine synthase domain | 0 | Direct |
| HAMP domain-like | 0 | Direct |
| Protein prenylyltransferase | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
| Homocysteine S-methyltransferase | 0 | Direct |
| L domain-like | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| CheW-like | 0 | Direct |
| Thymidylate synthase-complementing protein Thy1 | 0 | Direct |
| NadA-like | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| Undecaprenyl diphosphate synthase | 0 | Direct |
| RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
| PK C-terminal domain-like | 0 | Direct |
| Lumazine synthase | 0 | Direct |
| TTHA0583/YokD-like | 0 | Direct |
| Aspartate/ornithine carbamoyltransferase | 0 | Direct |
| PTS system IIB component-like | 0 | Direct |
| SSo0622-like | 0 | Direct |
| Notch domain | 0 | Direct |
| PPK N-terminal domain-like | 0 | Direct |
| S-adenosylmethionine synthetase | 0 | Direct |
| PTS IIb component | 0 | Direct |
| Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
| S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
| UBC-like | 0 | Direct |
| CoA-dependent acyltransferases | 0 | Direct |
| PilZ domain-like | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| TK C-terminal domain-like | 0 | Direct |
| HR1 repeat | 0 | Direct |
| AFP III-like domain | 0 | Direct |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Thiolase-like | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| CCHHC domain | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| CbiD-like | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| FMT C-terminal domain-like | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | Direct |
| Aminomethyltransferase beta-barrel domain | 0 | Direct |
| MoeA C-terminal domain-like | 0 | Direct |
| PH domain-like | 0.000000000000001936 | Direct |
| Fic-like | 0.000000000000004899 | Direct |
| Sensory domain-like | 0.00000000000003457 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0.0000000000001074 | Direct |
| TRAF domain-like | 0.0000000000003728 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0.000000000000477 | Direct |
| Molybdenum cofactor biosynthesis proteins | 0.0000000000004816 | Direct |
| RNI-like | 0.000000000001328 | Direct |
| FYVE/PHD zinc finger | 0.000000000006992 | Direct |
| Bromodomain | 0.000000000009154 | Direct |
| beta-beta-alpha zinc fingers | 0.00000000001206 | Direct |
| L30e-like | 0.00000000002283 | Direct |
| CCCH zinc finger | 0.00000000005556 | Direct |
| Homeodomain-like | 0.00000000008468 | Direct |
| Ricin B-like lectins | 0.0000000004246 | Direct |
| ClpP/crotonase | 0.0000000005885 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0.000000001918 | Direct |
| Phospholipase D/nuclease | 0.000000003911 | Direct |
| WW domain | 0.000000004169 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0.00000008581 | Direct |
| Single hybrid motif | 0.0000001291 | Direct |
| HprK N-terminal domain-like | 0.0000001376 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.0000001551 | Direct |
| Chromo domain-like | 0.000000728 | Direct |
| post-AAA+ oligomerization domain-like | 0.0000007907 | Direct |
| Ubiquitin-like | 0.00000213 | Direct |
| WD40 repeat-like | 0.0000058 | Direct |
| NHL repeat | 0.00001035 | Direct |
| PIN domain-like | 0.00001487 | Direct |
| Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | 0.00005404 | Direct |
| Second domain of FERM | 0.00006572 | Direct |
| GckA/TtuD-like | 0.00008149 | Direct |
| Glycosyl hydrolase domain | 0.000124 | Direct |
| ACP-like | 0.0001254 | Direct |
| TPR-like | 0.0002271 | Direct |
| SMAD/FHA domain | 0.0002389 | Direct |
| GAF domain-like | 0.0003524 | Direct |
| EF-hand | 0.0004953 | Direct |
| N-(deoxy)ribosyltransferase-like | 0.0008354 | Direct |
| beta-sandwich domain of Sec23/24 | 0.001017 | Inherited |
| Methenyltetrahydrofolate cyclohydrolase-like | 0.001254 | Inherited |
| Duplicated hybrid motif | 0.001348 | Inherited |
| Replicase NSP9 | 0.006099 | Inherited |
| Coronavirus NSP8-like | 0.006099 | Inherited |
| Coronavirus NSP10-like | 0.006099 | Inherited |
| Coronavirus NSP7-like | 0.006099 | Inherited |
| YWTD domain | 0.006582 | Inherited |
| Ran binding protein zinc finger-like | 0.007452 | Inherited |
| PX domain | 0.007538 | Inherited |
| HMG-box | 0.008695 | Inherited |
| MFS general substrate transporter | 0.008695 | Inherited |
| CRAL/TRIO domain | 0.009161 | Inherited |
| FabD/lysophospholipase-like | 0.01326 | Inherited |
| RNA-binding domain, RBD | 0.01888 | Inherited |
| SAP domain | 0.01937 | Inherited |
| Galactose oxidase, central domain | 0.02378 | Inherited |
| GroEL apical domain-like | 0.02417 | Inherited |
| Outer arm dynein light chain 1 | 0.03518 | Inherited |
| ACT-like | 0.03531 | Inherited |
| NSP3A-like | 0.04304 | Inherited |
| SCP-like | 0.04394 | Inherited |
| Acid proteases | 0.05354 | Inherited |
| PA domain | 0.0803 | Inherited |
| YrdC/RibB | 0.09132 | Inherited |
| DEATH domain | 0.1162 | Inherited |
| SARS Nsp1-like | 0.154 | Inherited |
| Tropomyosin | 0.1641 | Inherited |
| Chaperone J-domain | 0.1641 | Inherited |
| Cell wall binding repeat | 0.1951 | Inherited |
| Trypsin-like serine proteases | 0.2291 | Inherited |
| GTPase activation domain, GAP | 0.2399 | Inherited |
| Formin homology 2 domain (FH2 domain) | 0.24 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.2488 | Inherited |
| UBA-like | 0.2836 | Inherited |
| Hedgehog/intein (Hint) domain | 0.2973 | Inherited |
| Terpenoid synthases | 0.3087 | Inherited |
| MIT domain | 0.3462 | Inherited |
| MAPEG domain-like | 0.347 | Inherited |
| C-terminal domain of transcriptional repressors | 0.3814 | Inherited |
| C-type lectin-like | 0.4585 | Inherited |
| GroEL-intermediate domain like | 0.4931 | Inherited |
| Homing endonucleases | 0.5023 | Inherited |
| Multidrug efflux transporter AcrB transmembrane domain | 0.5305 | Inherited |
| Concanavalin A-like lectins/glucanases | 0.5347 | Inherited |
| HCP-like | 0.6215 | Inherited |
| Rubredoxin-like | 0.6406 | Inherited |
| Carbon-nitrogen hydrolase | 0.6954 | Inherited |
| UROD/MetE-like | 0.7699 | Inherited |
| Cobalamin (vitamin B12)-binding domain | 0.7862 | Inherited |
| Tudor/PWWP/MBT | 0.8839 | Inherited |
| NTF2-like | 0.9039 | Inherited |
| Starch-binding domain-like | 0.9703 | Inherited |
| Galactose-binding domain-like | 1 | Inherited |
| Lysozyme-like | 1 | Inherited |
| BRCT domain | 1 | Inherited |
| Adenine nucleotide alpha hydrolases-like | 1 | Inherited |
| "Winged helix" DNA-binding domain | 1 | Inherited |
| PreATP-grasp domain | 1 | Inherited |
| Ribonuclease H-like | 1 | Inherited |
| RmlC-like cupins | 1 | Inherited |
| Dehydroquinate synthase-like | 1 | Inherited |
| Cyclophilin-like | 1 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 1 | Inherited |
| Glycoside hydrolase/deacetylase | 1 | Inherited |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | Inherited |
| NagB/RpiA/CoA transferase-like | 1 | Inherited |
| Thioredoxin-like | 1 | Inherited |
| Heme oxygenase-like | 1 | Inherited |
| Sec63 N-terminal domain-like | 1 | Inherited |
| Nucleotide cyclase | 1 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
| Nucleotide-binding domain | 1 | Inherited |
| Kelch motif | 1 | Inherited |
| SGNH hydrolase | 1 | Inherited |
| Dihydrofolate reductase-like | 1 | Inherited |
| Dimeric alpha+beta barrel | 1 | Inherited |
| PheT/TilS domain | 1 | Inherited |
| Rudiment single hybrid motif | 1 | Inherited |
| TGS-like | 1 | Inherited |
| FMN-linked oxidoreductases | 1 | Inherited |
| Inosine monophosphate dehydrogenase (IMPDH) | 1 | Inherited |
| Phosphoglycerate mutase-like | 1 | Inherited |
| Six-hairpin glycosidases | 1 | Inherited |
| Zn-dependent exopeptidases | 1 | Inherited |
| tRNA-binding arm | 1 | Inherited |
| Kringle-like | 1 | Inherited |
| CheY-like | 1 | Inherited |
| Terpenoid cyclases/Protein prenyltransferases | 1 | Inherited |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | Inherited |
| DNase I-like | 1 | Inherited |
| lambda repressor-like DNA-binding domains | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| Glutamine synthetase, N-terminal domain | 1 | Inherited |
| Glutamine synthetase/guanido kinase | 1 | Inherited |
| Nicotinate/Quinolinate PRTase C-terminal domain-like | 1 | Inherited |
| alpha/beta-Hydrolases | 1 | Inherited |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| IpsF-like | 1 | Inherited |
| SIS domain | 1 | Inherited |
| Ribonuclease Rh-like | 1 | Inherited |
| Nudix | 1 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 1 | Inherited |
| beta-lactamase/transpeptidase-like | 1 | Inherited |
| HIT-like | 1 | Inherited |
| ADC-like | 1 | Inherited |
| post-HMGL domain-like | 1 | Inherited |
| Families 57/38 glycoside transferase middle domain | 1 | Inherited |
| Pentein | 1 | Inherited |
| Galactose mutarotase-like | 1 | Inherited |
| Nucleotidylyl transferase | 1 | Inherited |
| Clavaminate synthase-like | 1 | Inherited |
| cAMP-binding domain-like | 1 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 1 | Inherited |
| MesJ substrate recognition domain-like | 1 | Inherited |
| Dihydropteroate synthetase-like | 1 | Inherited |
| Cysteine proteinases | 1 | Inherited |
| GroES-like | 1 | Inherited |
| CYTH-like phosphatases | 1 | Inherited |
| PurM C-terminal domain-like | 1 | Inherited |
| Class II aaRS and biotin synthetases | 1 | Inherited |
| Cytochrome c | 1 | Inherited |
| SAICAR synthase-like | 1 | Inherited |
| PurM N-terminal domain-like | 1 | Inherited |
| HD-domain/PDEase-like | 1 | Inherited |
| FAD-binding/transporter-associated domain-like | 1 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
| Translation proteins | 1 | Inherited |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | Inherited |
| Riboflavin synthase domain-like | 1 | Inherited |
| Macro domain-like | 1 | Inherited |
| (Trans)glycosidases | 1 | Inherited |
| FAD-linked oxidases, C-terminal domain | 1 | Inherited |
| Prismane protein-like | 1 | Inherited |
| Globin-like | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| ADC synthase | 1 | Inherited |
| Phosphoglucomutase, first 3 domains | 1 | Inherited |
| HAD-like | 1 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | Inherited |
| dUTPase-like | 1 | Inherited |
| Nicotinate/Quinolinate PRTase N-terminal domain-like | 1 | Inherited |
| Zinc beta-ribbon | 1 | Inherited |
| Arabinanase/levansucrase/invertase | 1 | Inherited |
| CBS-domain pair | 1 | Inherited |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | Inherited |
| FAD-linked reductases, C-terminal domain | 1 | Inherited |
| Class I glutamine amidotransferase-like | 1 | Inherited |
| PDZ domain-like | 1 | Inherited |
| ALDH-like | 1 | Inherited |
| vWA-like | 1 | Inherited |
| Acetyl-CoA synthetase-like | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
| PFL-like glycyl radical enzymes | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| FAD/NAD(P)-binding domain | 1 | Inherited |
| Phosphoglucomutase, C-terminal domain | 1 | Inherited |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | Inherited |
| RuvA domain 2-like | 1 | Inherited |
| Succinyl-CoA synthetase domains | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (Not in SPEC)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56112,101288
56112 - Protein kinase-like (PK-like)
101288 - L27 domain | 0 | DIRECT |
55604,51261
55604 - Glucose permease domain IIB
51261 - Duplicated hybrid motif | 0 | DIRECT |
53850,56112
53850 - Periplasmic binding protein-like II
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55021,56112
55021 - ACT-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53448,51161
53448 - Nucleotide-diphospho-sugar transferases
51161 - Trimeric LpxA-like enzymes | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51230,52777
51230 - Single hybrid motif
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
52025,57850
52025 - PA domain
57850 - RING/U-box | 0 | DIRECT |
56235,53271
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
53271 - PRTase-like | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
55315,75217
55315 - L30e-like
75217 - alpha/beta knot | 0 | DIRECT |
56112,54427
56112 - Protein kinase-like (PK-like)
54427 - NTF2-like | 0 | DIRECT |
82282,51717
82282 - Homocysteine S-methyltransferase
51717 - Dihydropteroate synthetase-like | 0 | DIRECT |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
81301,81891
81301 - Nucleotidyltransferase
81891 - Poly A polymerase C-terminal region-like | 0 | DIRECT |
103190,47384
103190 - Sensory domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
52374,52540
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
81296,51445
81296 - E set domains
51445 - (Trans)glycosidases | 0 | DIRECT |
52540,51569
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | DIRECT |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,47473
56112 - Protein kinase-like (PK-like)
47473 - EF-hand | 0 | DIRECT |
52374,82114
52374 - Nucleotidylyl transferase
82114 - Riboflavin kinase-like | 0 | DIRECT |
57850,57667
57850 - RING/U-box
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
52540,47648
52540 - P-loop containing nucleoside triphosphate hydrolases
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
49599,50156
49599 - TRAF domain-like
50156 - PDZ domain-like | 0 | DIRECT |
53155,46767
53155 - Methylated DNA-protein cysteine methyltransferase domain
46767 - Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | DIRECT |
55608,56672
55608 - Homing endonucleases
56672 - DNA/RNA polymerases | 0 | DIRECT |
56112,57850
56112 - Protein kinase-like (PK-like)
57850 - RING/U-box | 0 | DIRECT |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | DIRECT |
161245,57850
161245 - Zinc hairpin stack
57850 - RING/U-box | 0 | DIRECT |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
81593,81891
81593 - Nucleotidyltransferase substrate binding subunit/domain
81891 - Poly A polymerase C-terminal region-like | 0 | DIRECT |
88697,52374
88697 - PUA domain-like
52374 - Nucleotidylyl transferase | 0 | DIRECT |
56112,52799
56112 - Protein kinase-like (PK-like)
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
56112,50998
56112 - Protein kinase-like (PK-like)
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
82199,81822
82199 - SET domain
81822 - RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
55666,46915
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
81296,54001
81296 - E set domains
54001 - Cysteine proteinases | 0 | DIRECT |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
68906,57850
68906 - SAP domain
57850 - RING/U-box | 0 | DIRECT |
56219,56672
56219 - DNase I-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | DIRECT |
53300,57850
53300 - vWA-like
57850 - RING/U-box | 0 | DIRECT |
50800,51621
50800 - PK beta-barrel domain-like
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
56784,52540
56784 - HAD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47807,53098
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like | 0 | DIRECT |
158472,55785
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
117839,117839
117839 - WWE domain
117839 - WWE domain | 0 | DIRECT |
55083,51717
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
51717 - Dihydropteroate synthetase-like | 0 | DIRECT |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
57884,46689
57884 - Ada DNA repair protein, N-terminal domain (N-Ada 10)
46689 - Homeodomain-like | 0 | DIRECT |
51726,51726
51726 - UROD/MetE-like
51726 - UROD/MetE-like | 0 | DIRECT |
52151,51412
52151 - FabD/lysophospholipase-like
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
52172,55785
52172 - CheY-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
52949,52540
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
64484,-9
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
-9 - PDB | 0 | DIRECT |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
47212,56112
47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55781,47384
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
48452,140931
48452 - TPR-like
140931 - Fic-like | 0 | DIRECT |
47648,52418
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
53474,53335
53474 - alpha/beta-Hydrolases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
51230,51230
51230 - Single hybrid motif
51230 - Single hybrid motif | 0 | DIRECT |
63882,53218
63882 - MoeA N-terminal region -like
53218 - Molybdenum cofactor biosynthesis proteins | 0 | DIRECT |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
53474,54631
53474 - alpha/beta-Hydrolases
54631 - CBS-domain pair | 0 | DIRECT |
55205,52540
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53790,53335
53790 - Tetrapyrrole methylase
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
56112,52540
56112 - Protein kinase-like (PK-like)
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | DIRECT |
50037,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | DIRECT |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
53098,53098
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | DIRECT |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | DIRECT |
56112,50044
56112 - Protein kinase-like (PK-like)
50044 - SH3-domain | 0 | DIRECT |
52799,56091
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
55804,52794
55804 - Phoshotransferase/anion transport protein
52794 - PTS system IIB component-like | 0 | DIRECT |
88697,75217
88697 - PUA domain-like
75217 - alpha/beta knot | 0 | DIRECT |
47986,56112
47986 - DEATH domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,48403
56112 - Protein kinase-like (PK-like)
48403 - Ankyrin repeat | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
56112,50978
56112 - Protein kinase-like (PK-like)
50978 - WD40 repeat-like | 0 | DIRECT |
158472,47384
158472 - HAMP domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
53335,53335
53335 - S-adenosyl-L-methionine-dependent methyltransferases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
102114,53383
102114 - Radical SAM enzymes
53383 - PLP-dependent transferases | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
52821,52821
52821 - Rhodanese/Cell cycle control phosphatase
52821 - Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
55116,101262
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
101262 - Methenyltetrahydrofolate cyclohydrolase-like | 0 | DIRECT |
47836,47943
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
55890,55874
55890 - Sporulation response regulatory protein Spo0B
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
64484,64484
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
53850,54913
53850 - Periplasmic binding protein-like II
54913 - GlnB-like | 0 | DIRECT |
48403,47769
48403 - Ankyrin repeat
47769 - SAM/Pointed domain | 0 | DIRECT |
53613,52374
53613 - Ribokinase-like
52374 - Nucleotidylyl transferase | 0 | DIRECT |
54277,56112
54277 - CAD & PB1 domains
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | DIRECT |
109604,55021
109604 - HD-domain/PDEase-like
55021 - ACT-like | 0 | DIRECT |
54160,82199
54160 - Chromo domain-like
82199 - SET domain | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
88798,50249
88798 - N-terminal, heterodimerisation domain of RBP7 (RpoE)
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
51197,53335
51197 - Clavaminate synthase-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
52540,53271
52540 - P-loop containing nucleoside triphosphate hydrolases
53271 - PRTase-like | 0 | DIRECT |
53328,50486
53328 - Formyltransferase
50486 - FMT C-terminal domain-like | 0 | DIRECT |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | DIRECT |
50249,89550
50249 - Nucleic acid-binding proteins
89550 - PHP domain-like | 0 | DIRECT |
46689,53697
46689 - Homeodomain-like
53697 - SIS domain | 0 | DIRECT |
54160,53335
54160 - Chromo domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
52047,56112
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
51621,52935
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like | 0 | DIRECT |
54197,54197
54197 - HIT-like
54197 - HIT-like | 0 | DIRECT |
69593,56801
69593 - Glycerol-3-phosphate (1)-acyltransferase
56801 - Acetyl-CoA synthetase-like | 0 | DIRECT |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
88697,53335
88697 - PUA domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | DIRECT |
51735,75615
51735 - NAD(P)-binding Rossmann-fold domains
75615 - Siroheme synthase middle domains-like | 0 | DIRECT |
57850,101898
57850 - RING/U-box
101898 - NHL repeat | 0 | DIRECT |
54277,57889
54277 - CAD & PB1 domains
57889 - Cysteine-rich domain | 0 | DIRECT |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55874,52172
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like | 0 | DIRECT |
57850,50978
57850 - RING/U-box
50978 - WD40 repeat-like | 0 | DIRECT |
50249,56300
50249 - Nucleic acid-binding proteins
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
56672,90234
56672 - DNA/RNA polymerases
90234 - Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
57953,49599
57953 - Trimerization domain of TRAF
49599 - TRAF domain-like | 0 | DIRECT |
90209,57850
90209 - Ran binding protein zinc finger-like
57850 - RING/U-box | 0 | DIRECT |
50044,53335
50044 - SH3-domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | DIRECT |
55729,47370
55729 - Acyl-CoA N-acyltransferases (Nat)
47370 - Bromodomain | 0 | DIRECT |
55073,56112
55073 - Nucleotide cyclase
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53850,55785
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
56112,116846
56112 - Protein kinase-like (PK-like)
116846 - MIT domain | 0 | DIRECT |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | DIRECT |
55781,55874
55781 - GAF domain-like
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
52172,47226
52172 - CheY-like
47226 - Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
56672,46919
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | DIRECT |
47226,55052
47226 - Histidine-containing phosphotransfer domain, HPT domain
55052 - CheY-binding domain of CheA | 0 | DIRECT |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | DIRECT |
48013,53335
48013 - NusB-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
56112,48452
56112 - Protein kinase-like (PK-like)
48452 - TPR-like | 0 | DIRECT |
52540,52402
52540 - P-loop containing nucleoside triphosphate hydrolases
52402 - Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
52418,54680
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
54680 - Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | DIRECT |
55116,55116
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | DIRECT |
52113,142921
52113 - BRCT domain
142921 - WGR domain-like | 0 | DIRECT |
51569,51269
51569 - Aldolase
51269 - AFP III-like domain | 0 | DIRECT |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | DIRECT |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | DIRECT |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | DIRECT |
75217,54593
75217 - alpha/beta knot
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
53335,53383
53335 - S-adenosyl-L-methionine-dependent methyltransferases
53383 - PLP-dependent transferases | 0 | DIRECT |
75217,109604
75217 - alpha/beta knot
109604 - HD-domain/PDEase-like | 0 | DIRECT |
53448,69765
53448 - Nucleotide-diphospho-sugar transferases
69765 - IpsF-like | 0 | DIRECT |
51110,51110
51110 - alpha-D-mannose-specific plant lectins
51110 - alpha-D-mannose-specific plant lectins | 0 | DIRECT |
53448,50370
53448 - Nucleotide-diphospho-sugar transferases
50370 - Ricin B-like lectins | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
56796,55205
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like | 0 | DIRECT |
57783,47954
57783 - Zinc beta-ribbon
47954 - Cyclin-like | 0 | DIRECT |
143437,53335
143437 - THUMP domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
51621,55804
51621 - Phosphoenolpyruvate/pyruvate domain
55804 - Phoshotransferase/anion transport protein | 0 | DIRECT |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | DIRECT |
51391,53613
51391 - Thiamin phosphate synthase
53613 - Ribokinase-like | 0 | DIRECT |
53335,50249
53335 - S-adenosyl-L-methionine-dependent methyltransferases
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
53218,63867
53218 - Molybdenum cofactor biosynthesis proteins
63867 - MoeA C-terminal domain-like | 0 | DIRECT |
55594,47831
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
49562,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
69593,47473
69593 - Glycerol-3-phosphate (1)-acyltransferase
47473 - EF-hand | 0 | DIRECT |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56042,53328
56042 - PurM C-terminal domain-like
53328 - Formyltransferase | 0 | DIRECT |
49879,57850
49879 - SMAD/FHA domain
57850 - RING/U-box | 0 | DIRECT |
55931,48034
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain | 0 | DIRECT |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
50729,69322
50729 - PH domain-like
69322 - Tricorn protease domain 2 | 0 | DIRECT |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | DIRECT |
57440,56112
57440 - Kringle-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53448,53448
53448 - Nucleotide-diphospho-sugar transferases
53448 - Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
57774,52540
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
50486,51735
50486 - FMT C-terminal domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
52833,47384
52833 - Thioredoxin-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
55785,55781
55785 - PYP-like sensor domain (PAS domain)
55781 - GAF domain-like | 0 | DIRECT |
54791,50249
54791 - Eukaryotic type KH-domain (KH-domain type I)
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | DIRECT |
56214,56214
56214 - 4'-phosphopantetheinyl transferase
56214 - 4'-phosphopantetheinyl transferase | 0 | DIRECT |
101288,101288
101288 - L27 domain
101288 - L27 domain | 0 | DIRECT |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53756,53756
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53756 - UDP-Glycosyltransferase/glycogen phosphorylase | 0 | DIRECT |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | DIRECT |
46585,49562
46585 - HR1 repeat
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57903,57850
57903 - FYVE/PHD zinc finger
57850 - RING/U-box | 0 | DIRECT |
63570,56204
63570 - PABC (PABP) domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
52210,51735
52210 - Succinyl-CoA synthetase domains
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
47413,53335
47413 - lambda repressor-like DNA-binding domains
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
63999,63862
63999 - Thiamin pyrophosphokinase, catalytic domain
63862 - Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
55785,55890
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B | 0 | DIRECT |
47802,81585
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like | 0 | DIRECT |
51717,47644
51717 - Dihydropteroate synthetase-like
47644 - Methionine synthase domain | 0 | DIRECT |
103190,158472
103190 - Sensory domain-like
158472 - HAMP domain-like | 0 | DIRECT |
48452,57850
48452 - TPR-like
57850 - RING/U-box | 0 | DIRECT |
53633,53720
53633 - Carbamate kinase-like
53720 - ALDH-like | 0 | DIRECT |
55785,47384
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
81301,47473
81301 - Nucleotidyltransferase
47473 - EF-hand | 0 | DIRECT |
57716,50156
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like | 0 | DIRECT |
52335,53927
52335 - Methylglyoxal synthase-like
53927 - Cytidine deaminase-like | 0 | DIRECT |
54637,52151
54637 - Thioesterase/thiol ester dehydrase-isomerase
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
49599,57953
49599 - TRAF domain-like
57953 - Trimerization domain of TRAF | 0 | DIRECT |
81301,81593
81301 - Nucleotidyltransferase
81593 - Nucleotidyltransferase substrate binding subunit/domain | 0 | DIRECT |
-9,-7
-9 - PDB
-7 - CATH | 0 | DIRECT |
81631,81301
81631 - PAP/OAS1 substrate-binding domain
81301 - Nucleotidyltransferase | 0 | DIRECT |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
52540,57802
52540 - P-loop containing nucleoside triphosphate hydrolases
57802 - Rubredoxin-like | 0 | DIRECT |
52794,52794
52794 - PTS system IIB component-like
52794 - PTS system IIB component-like | 0 | DIRECT |
57850,49599
57850 - RING/U-box
49599 - TRAF domain-like | 0 | DIRECT |
56112,50985
56112 - Protein kinase-like (PK-like)
50985 - RCC1/BLIP-II | 0 | DIRECT |
56112,64268
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | DIRECT |
48452,53335
48452 - TPR-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
53271,53271
53271 - PRTase-like
53271 - PRTase-like | 0 | DIRECT |
53067,56112
53067 - Actin-like ATPase domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
54236,90209
54236 - Ubiquitin-like
90209 - Ran binding protein zinc finger-like | 0 | DIRECT |
51735,48256
51735 - NAD(P)-binding Rossmann-fold domains
48256 - Citrate synthase | 0 | DIRECT |
50249,53335
50249 - Nucleic acid-binding proteins
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
55088,48081
55088 - Methyl-coenzyme M reductase subunits
48081 - Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | DIRECT |
52317,47648
52317 - Class I glutamine amidotransferase-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
56235,53697
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
53697 - SIS domain | 0 | DIRECT |
53756,53067
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53067 - Actin-like ATPase domain | 0 | DIRECT |
46785,56112
46785 - "Winged helix" DNA-binding domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81296,101898
81296 - E set domains
101898 - NHL repeat | 0 | DIRECT |
48403,57850
48403 - Ankyrin repeat
57850 - RING/U-box | 0 | DIRECT |
56112,90257
56112 - Protein kinase-like (PK-like)
90257 - Myosin rod fragments | 0 | DIRECT |
46785,82114
46785 - "Winged helix" DNA-binding domain
82114 - Riboflavin kinase-like | 0 | DIRECT |
49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
52540,75138
52540 - P-loop containing nucleoside triphosphate hydrolases
75138 - HprK N-terminal domain-like | 0 | DIRECT |
143724,56024
143724 - PHP14-like
56024 - Phospholipase D/nuclease | 0 | DIRECT |
53062,55594
53062 - PTS system fructose IIA component-like
55594 - HPr-like | 0 | DIRECT |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | DIRECT |
53955,56601
53955 - Lysozyme-like
56601 - beta-lactamase/transpeptidase-like | 0 | DIRECT |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
52317,56322
52317 - Class I glutamine amidotransferase-like
56322 - ADC synthase | 0 | DIRECT |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
52009,51621
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | DIRECT |
143437,52402
143437 - THUMP domain-like
52402 - Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
64268,49562
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
46785,57903
46785 - "Winged helix" DNA-binding domain
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
53901,55718
53901 - Thiolase-like
55718 - SCP-like | 0 | DIRECT |
55154,56091
55154 - CYTH-like phosphatases
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | DIRECT |
56672,55608
56672 - DNA/RNA polymerases
55608 - Homing endonucleases | 0 | DIRECT |
88802,88697
88802 - Pre-PUA domain
88697 - PUA domain-like | 0 | DIRECT |
75217,75217
75217 - alpha/beta knot
75217 - alpha/beta knot | 0 | DIRECT |
50998,56112
50998 - Quinoprotein alcohol dehydrogenase-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57850,48371
57850 - RING/U-box
48371 - ARM repeat | 0 | DIRECT |
54919,54919
54919 - Nucleoside diphosphate kinase, NDK
54919 - Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
50965,52540
50965 - Galactose oxidase, central domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
116846,116846
116846 - MIT domain
116846 - MIT domain | 0 | DIRECT |
48371,117839
48371 - ARM repeat
117839 - WWE domain | 0 | DIRECT |
49899,56112
49899 - Concanavalin A-like lectins/glucanases
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49785,50985
49785 - Galactose-binding domain-like
50985 - RCC1/BLIP-II | 0 | DIRECT |
50156,56112
50156 - PDZ domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56672,51294
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
56112,54928
56112 - Protein kinase-like (PK-like)
54928 - RNA-binding domain, RBD | 0 | DIRECT |
52151,55048
52151 - FabD/lysophospholipase-like
55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | DIRECT |
52087,46966
52087 - CRAL/TRIO domain
46966 - Spectrin repeat | 0 | DIRECT |
55112,55112
55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase
55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
82549,101473
82549 - DAK1/DegV-like
101473 - DhaL-like | 0 | DIRECT |
140356,143724
140356 - PPK N-terminal domain-like
143724 - PHP14-like | 0 | DIRECT |
49562,48350
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | DIRECT |
57850,57933
57850 - RING/U-box
57933 - TAZ domain | 0 | DIRECT |
53448,51182
53448 - Nucleotide-diphospho-sugar transferases
51182 - RmlC-like cupins | 0 | DIRECT |
49785,159034
49785 - Galactose-binding domain-like
159034 - Mib/herc2 domain-like | 0 | DIRECT |
75615,53790
75615 - Siroheme synthase middle domains-like
53790 - Tetrapyrrole methylase | 0 | DIRECT |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | DIRECT |
51294,56672
51294 - Hedgehog/intein (Hint) domain
56672 - DNA/RNA polymerases | 0 | DIRECT |
53850,54782
53850 - Periplasmic binding protein-like II
54782 - Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | DIRECT |
52794,55804
52794 - PTS system IIB component-like
55804 - Phoshotransferase/anion transport protein | 0 | DIRECT |
47757,53335
47757 - Chemotaxis receptor methyltransferase CheR, N-terminal domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
57850,159034
57850 - RING/U-box
159034 - Mib/herc2 domain-like | 0 | DIRECT |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | DIRECT |
81585,81301
81585 - PsbU/PolX domain-like
81301 - Nucleotidyltransferase | 0 | DIRECT |
47644,52242
47644 - Methionine synthase domain
52242 - Cobalamin (vitamin B12)-binding domain | 0 | DIRECT |
81995,56112
81995 - beta-sandwich domain of Sec23/24
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | DIRECT |
47769,56399
47769 - SAM/Pointed domain
56399 - ADP-ribosylation | 0 | DIRECT |
49309,49309
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
51569,54909
51569 - Aldolase
54909 - Dimeric alpha+beta barrel | 0 | DIRECT |
54495,57850
54495 - UBC-like
57850 - RING/U-box | 0 | DIRECT |
161219,161245
161219 - CHY zinc finger-like
161245 - Zinc hairpin stack | 0 | DIRECT |
50465,52540
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
159034,57850
159034 - Mib/herc2 domain-like
57850 - RING/U-box | 0 | DIRECT |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
46785,53335
46785 - "Winged helix" DNA-binding domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
55257,47789
55257 - RBP11-like subunits of RNA polymerase
47789 - C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
52242,56507
52242 - Cobalamin (vitamin B12)-binding domain
56507 - Methionine synthase activation domain-like | 0 | DIRECT |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
52058,56112
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
46589,55729
46589 - tRNA-binding arm
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | DIRECT |
55666,54791
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
57889,111331
57889 - Cysteine-rich domain
111331 - NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
54236,56112
54236 - Ubiquitin-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | DIRECT |
53633,55021
53633 - Carbamate kinase-like
55021 - ACT-like | 0 | DIRECT |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
53335,50965
53335 - S-adenosyl-L-methionine-dependent methyltransferases
50965 - Galactose oxidase, central domain | 0 | DIRECT |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | DIRECT |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
75138,53659
75138 - HprK N-terminal domain-like
53659 - Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
55874,50341
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
50341 - CheW-like | 0 | DIRECT |
53448,52266
53448 - Nucleotide-diphospho-sugar transferases
52266 - SGNH hydrolase | 0 | DIRECT |
56553,55257
56553 - Insert subdomain of RNA polymerase alpha subunit
55257 - RBP11-like subunits of RNA polymerase | 0 | DIRECT |
-9,51569
-9 - PDB
51569 - Aldolase | 0 | DIRECT |
48403,52113
48403 - Ankyrin repeat
52113 - BRCT domain | 0 | DIRECT |
52402,52821
52402 - Adenine nucleotide alpha hydrolases-like
52821 - Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
55620,55083
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53633,55729
53633 - Carbamate kinase-like
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
49265,63825
49265 - Fibronectin type III
63825 - YWTD domain | 0 | DIRECT |
55729,46589
55729 - Acyl-CoA N-acyltransferases (Nat)
46589 - tRNA-binding arm | 0 | DIRECT |
51735,52540
51735 - NAD(P)-binding Rossmann-fold domains
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
56112,103243
56112 - Protein kinase-like (PK-like)
103243 - KA1-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
51569,53223
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
48371,48403
48371 - ARM repeat
48403 - Ankyrin repeat | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
47807,56672
47807 - 5' to 3' exonuclease, C-terminal subdomain
56672 - DNA/RNA polymerases | 0 | DIRECT |
53448,56784
53448 - Nucleotide-diphospho-sugar transferases
56784 - HAD-like | 0 | DIRECT |
89550,53098
89550 - PHP domain-like
53098 - Ribonuclease H-like | 0 | DIRECT |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
52540,57774
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
50965,51197
50965 - Galactose oxidase, central domain
51197 - Clavaminate synthase-like | 0 | DIRECT |
55021,51735
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,57716
52540 - P-loop containing nucleoside triphosphate hydrolases
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
55052,47384
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
49265,49899
49265 - Fibronectin type III
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
55781,55785
55781 - GAF domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
63825,49265
63825 - YWTD domain
49265 - Fibronectin type III | 0 | DIRECT |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | DIRECT |
69360,51445
69360 - Cell wall binding repeat
51445 - (Trans)glycosidases | 0 | DIRECT |
52540,55729
52540 - P-loop containing nucleoside triphosphate hydrolases
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
56112,48726
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin | 0 | DIRECT |
48439,49594
48439 - Protein prenylyltransferase
49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | DIRECT |
52540,88697
52540 - P-loop containing nucleoside triphosphate hydrolases
88697 - PUA domain-like | 0 | DIRECT |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | DIRECT |
53633,88697
53633 - Carbamate kinase-like
88697 - PUA domain-like | 0 | DIRECT |
103190,55785
103190 - Sensory domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
89837,89837
89837 - Doublecortin (DC)
89837 - Doublecortin (DC) | 0 | DIRECT |
50692,47648
50692 - ADC-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
53597,55831
53597 - Dihydrofolate reductase-like
55831 - Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
56037,53271
56037 - PheT/TilS domain
53271 - PRTase-like | 0 | DIRECT |
54928,51197
54928 - RNA-binding domain, RBD
51197 - Clavaminate synthase-like | 0 | DIRECT |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
63380,63380
63380 - Riboflavin synthase domain-like
63380 - Riboflavin synthase domain-like | 0 | DIRECT |
47831,52009
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain | 0 | DIRECT |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
103473,53335
103473 - MFS general substrate transporter
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
51569,47473
51569 - Aldolase
47473 - EF-hand | 0 | DIRECT |
90229,57850
90229 - CCCH zinc finger
57850 - RING/U-box | 0 | DIRECT |
64268,56112
64268 - PX domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52113,47802
52113 - BRCT domain
47802 - DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
81631,57756
81631 - PAP/OAS1 substrate-binding domain
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
53271,51366
53271 - PRTase-like
51366 - Ribulose-phoshate binding barrel | 0 | DIRECT |
46915,54211
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
52540,81301
52540 - P-loop containing nucleoside triphosphate hydrolases
81301 - Nucleotidyltransferase | 0 | DIRECT |
51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0 | DIRECT |
54593,53784
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
53784 - Phosphofructokinase | 0 | DIRECT |
47592,90209
47592 - SWIB/MDM2 domain
90209 - Ran binding protein zinc finger-like | 0 | DIRECT |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | DIRECT |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | DIRECT |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57667,54928
57667 - beta-beta-alpha zinc fingers
54928 - RNA-binding domain, RBD | 0 | DIRECT |
51713,88802
51713 - tRNA-guanine transglycosylase
88802 - Pre-PUA domain | 0 | DIRECT |
49594,52075
49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
52075 - Outer arm dynein light chain 1 | 0 | DIRECT |
89000,110921
89000 - post-HMGL domain-like
110921 - 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | DIRECT |
117281,51197
117281 - Kelch motif
51197 - Clavaminate synthase-like | 0 | DIRECT |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49599,160088
49599 - TRAF domain-like
160088 - NRDP1 C-terminal domain-like | 0 | DIRECT |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | DIRECT |
52935,52009
52935 - PK C-terminal domain-like
52009 - Phosphohistidine domain | 0 | DIRECT |
54160,55729
54160 - Chromo domain-like
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
55021,55021
55021 - ACT-like
55021 - ACT-like | 0 | DIRECT |
56112,55681
56112 - Protein kinase-like (PK-like)
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81891,109604
81891 - Poly A polymerase C-terminal region-like
109604 - HD-domain/PDEase-like | 0 | DIRECT |
47391,52540
47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47384,55874
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
56059,52009
56059 - Glutathione synthetase ATP-binding domain-like
52009 - Phosphohistidine domain | 0 | DIRECT |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | DIRECT |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
53613,51391
53613 - Ribokinase-like
51391 - Thiamin phosphate synthase | 0 | DIRECT |
52172,52172
52172 - CheY-like
52172 - CheY-like | 0 | DIRECT |
53335,51905
53335 - S-adenosyl-L-methionine-dependent methyltransferases
51905 - FAD/NAD(P)-binding domain | 0 | DIRECT |
49562,51045
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
51045 - WW domain | 0 | DIRECT |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
53335,81799
53335 - S-adenosyl-L-methionine-dependent methyltransferases
81799 - Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
52518,52467
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain | 0.000000000000001409 | DIRECT |
52467,52518
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0.000000000000001409 | DIRECT |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.000000000000007509 | DIRECT |
88723,47807
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain | 0.0000000000001074 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.0000000000006475 | DIRECT |
52047,52058
52047 - RNI-like
52058 - L domain-like | 0.000000000004556 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0.00000000007955 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.00000000007955 | DIRECT |
51735,51735
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.0000000005044 | DIRECT |
109604,81301
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase | 0.00000001393 | DIRECT |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0.00000002213 | DIRECT |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0.0000001498 | DIRECT |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0.0000002024 | DIRECT |
51011,81296
51011 - Glycosyl hydrolase domain
81296 - E set domains | 0.0000002024 | DIRECT |
81296,49452
81296 - E set domains
49452 - Starch-binding domain-like | 0.0000002024 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0.0000007907 | DIRECT |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0.000001393 | DIRECT |
51206,56112
51206 - cAMP-binding domain-like
56112 - Protein kinase-like (PK-like) | 0.000003736 | DIRECT |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0.000004246 | DIRECT |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0.000005442 | DIRECT |
81301,81271
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.000006691 | DIRECT |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.000009861 | DIRECT |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.00003311 | DIRECT |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0.00006854 | DIRECT |
47336,53474
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.00006854 | DIRECT |
74650,48208
74650 - Galactose mutarotase-like
48208 - Six-hairpin glycosidases | 0.00007426 | DIRECT |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0.00009991 | DIRECT |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.0002522 | DIRECT |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0.0003719 | DIRECT |
-9,-9
-9 - PDB
-9 - PDB | 0.0004755 | DIRECT |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.0008354 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.002445 | INHERITED FROM: Protein-tyrosine kinases || Aminoacyltransferases || Non-specific protein-tyrosine kinase || RING-type E3 ubiquitin transferase || Transferring phosphorus-containing groups |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.002532 | INHERITED FROM: Transferring one-carbon groups || Aspartate carbamoyltransferase || Carboxy- and carbamoyltransferases |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.002788 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
52374,52374
52374 - Nucleotidylyl transferase
52374 - Nucleotidylyl transferase | 0.00533 | INHERITED FROM: Ethanolamine-phosphate cytidylyltransferase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0.006099 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.006099 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.006099 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Transferring phosphorus-containing groups |
51445,69360
51445 - (Trans)glycosidases
69360 - Cell wall binding repeat | 0.006582 | INHERITED FROM: Dextransucrase || Glycosyltransferases || Hexosyltransferases |
69360,69360
69360 - Cell wall binding repeat
69360 - Cell wall binding repeat | 0.006582 | INHERITED FROM: Dextransucrase || Glycosyltransferases || Hexosyltransferases |
53335,51735
53335 - S-adenosyl-L-methionine-dependent methyltransferases
51735 - NAD(P)-binding Rossmann-fold domains | 0.008695 | INHERITED FROM: Transferring groups other than amino-acyl groups || Acyltransferases || Lovastatin nonaketide synthase |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0.009161 | INHERITED FROM: 1-phosphatidylinositol 4-kinase || Transferring phosphorus-containing groups |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0.01334 | INHERITED FROM: Aminoacyltransferases || Acyltransferases || RING-type E3 ubiquitin transferase |
51246,55326
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like | 0.02227 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase || Transferring one-carbon groups || Hydroxymethyl-, formyl- and related transferases |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.0223 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases || Transferring phosphorus-containing groups |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0.02289 | INHERITED FROM: Protein-tyrosine kinases || Receptor protein-tyrosine kinase || Transferring phosphorus-containing groups |
51690,-9
51690 - Nicotinate/Quinolinate PRTase C-terminal domain-like
-9 - PDB | 0.02289 | INHERITED FROM: Nicotinamide phosphoribosyltransferase || Pentosyltransferases || Glycosyltransferases |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.05243 | INHERITED FROM: Protein-tyrosine kinases || Aminoacyltransferases || Non-specific protein-tyrosine kinase || RING-type E3 ubiquitin transferase |
57756,51283
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0.07349 | INHERITED FROM: RNA-directed DNA polymerase || Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorus-containing groups |
51283,50630
51283 - dUTPase-like
50630 - Acid proteases | 0.07349 | INHERITED FROM: RNA-directed DNA polymerase || Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorus-containing groups |
55785,55073
55785 - PYP-like sensor domain (PAS domain)
55073 - Nucleotide cyclase | 0.07873 | INHERITED FROM: Diguanylate cyclase || Nucleotidyltransferases |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.1221 | INHERITED FROM: RNA-directed DNA polymerase || Nucleotidyltransferases || DNA-directed DNA polymerase || Transferring phosphorus-containing groups |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0.154 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.1641 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0.3814 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase || Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
55681,50037
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors | 0.3814 | INHERITED FROM: Pantothenate kinase || Phosphotransferases with an alcohol group as acceptor |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.4464 | INHERITED FROM: RNA-directed RNA polymerase || mRNA (guanine-N(7)-)-methyltransferase || Nucleotidyltransferases || Polynucleotide 5'-hydroxyl-kinase || Transferring alkyl or aryl groups, other than methyl groups || tRNA dimethylallyltransferase || Methyltransferase cap1 |
46626,46626
46626 - Cytochrome c
46626 - Cytochrome c | 0.471 | INHERITED FROM: Thiosulfotransferases || Transferring sulfur-containing groups |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.4931 | INHERITED FROM: 1-phosphatidylinositol-3-phosphate 5-kinase || Phosphotransferases with an alcohol group as acceptor |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.5346 | INHERITED FROM: Protein-tyrosine kinases || Receptor protein-tyrosine kinase || Transferring phosphorus-containing groups |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.6922 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
47336,52777
47336 - ACP-like
52777 - CoA-dependent acyltransferases | 0.7138 | INHERITED FROM: Transferring groups other than amino-acyl groups || Acyltransferases || Lovastatin nonaketide synthase |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0.7712 | INHERITED FROM: Transferring one-carbon groups || Acetyl-CoA carboxytransferase || Carboxy- and carbamoyltransferases |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.7872 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9324 | INHERITED FROM: Non-specific serine/threonine protein kinase || Protein-serine/threonine kinases |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 1 | INHERITED FROM: Aspartate carbamoyltransferase |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 1 | INHERITED FROM: Aspartate carbamoyltransferase || Carboxy- and carbamoyltransferases |
82829,56037
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 1 | INHERITED FROM: Selenide, water dikinase || Phosphoribosylglycinamide formyltransferase || Phosphotransferases with paired acceptors || Thiamine-phosphate kinase |
55620,55620
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55620 - Tetrahydrobiopterin biosynthesis enzymes-like | 1 | INHERITED FROM: Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase || Dihydropteroate synthase |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 1 | INHERITED FROM: mRNA guanylyltransferase |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 1 | INHERITED FROM: Lysyltransferase |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 1 | INHERITED FROM: Protein-histidine kinases |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 1 | INHERITED FROM: Hexosyltransferases |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 1 | INHERITED FROM: Alkylglycerone-phosphate synthase || Transferring alkyl or aryl groups, other than methyl groups |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | INHERITED FROM: Aspartate carbamoyltransferase || Carboxy- and carbamoyltransferases |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Shikimate kinase || 3-phosphoshikimate 1-carboxyvinyltransferase || Transferring alkyl or aryl groups, other than methyl groups |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
56042,55326
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | INHERITED FROM: Aspartate carbamoyltransferase || Carboxy- and carbamoyltransferases |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 1 | INHERITED FROM: Cyclomaltodextrin glucanotransferase || Starch synthase (maltosyl-transferring) || 1,4-alpha-glucan branching enzyme || Glycosyltransferases || Hexosyltransferases |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 1 | INHERITED FROM: Sulfate adenylyltransferase || Nucleotidyltransferases || Adenylyl-sulfate kinase || Transferring phosphorus-containing groups |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Fatty-acid synthase system || [Acyl-carrier-protein] S-acetyltransferase || [Acyl-carrier-protein] S-malonyltransferase || Beta-ketoacyl-[acyl-carrier-protein] synthase I || 2-methylbutanoate polyketide synthase |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 1 | INHERITED FROM: ATP citrate synthase || Acyl groups converted into alkyl groups on transfer |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: Phosphoribosylglycinamide formyltransferase || Aspartate carbamoyltransferase |
53383,53383
53383 - PLP-dependent transferases
53383 - PLP-dependent transferases | 1 | INHERITED FROM: Methionine S-methyltransferase |
52402,82829
52402 - Adenine nucleotide alpha hydrolases-like
82829 - MesJ substrate recognition domain-like | 1 | INHERITED FROM: Hypoxanthine phosphoribosyltransferase |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 1 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase || Methyltransferases |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 1 | INHERITED FROM: Protein-serine/threonine kinases || cGMP-dependent protein kinase |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 1 | INHERITED FROM: Beta-ketoacyl-[acyl-carrier-protein] synthase I |
54675,51690
54675 - Nicotinate/Quinolinate PRTase N-terminal domain-like
51690 - Nicotinate/Quinolinate PRTase C-terminal domain-like | 1 | INHERITED FROM: Nicotinate-nucleotide diphosphorylase (carboxylating) || Pentosyltransferases || Glycosyltransferases |
54368,55931
54368 - Glutamine synthetase, N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 1 | INHERITED FROM: Protein S-acyltransferase |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Aspartate carbamoyltransferase || Carboxy- and carbamoyltransferases |
51569,89000
51569 - Aldolase
89000 - post-HMGL domain-like | 1 | INHERITED FROM: Acyltransferases || 2-isopropylmalate synthase || Acyl groups converted into alkyl groups on transfer |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56112,101288
56112 - Protein kinase-like (PK-like)
101288 - L27 domain | 0 | Direct |
55604,51261
55604 - Glucose permease domain IIB
51261 - Duplicated hybrid motif | 0 | Direct |
53850,56112
53850 - Periplasmic binding protein-like II
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55021,56112
55021 - ACT-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53448,51161
53448 - Nucleotide-diphospho-sugar transferases
51161 - Trimeric LpxA-like enzymes | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
57850,52540
57850 - RING/U-box
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51230,52777
51230 - Single hybrid motif
52777 - CoA-dependent acyltransferases | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
52025,57850
52025 - PA domain
57850 - RING/U-box | 0 | Direct |
56235,53271
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
53271 - PRTase-like | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
55315,75217
55315 - L30e-like
75217 - alpha/beta knot | 0 | Direct |
56112,54427
56112 - Protein kinase-like (PK-like)
54427 - NTF2-like | 0 | Direct |
82282,51717
82282 - Homocysteine S-methyltransferase
51717 - Dihydropteroate synthetase-like | 0 | Direct |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
81301,81891
81301 - Nucleotidyltransferase
81891 - Poly A polymerase C-terminal region-like | 0 | Direct |
103190,47384
103190 - Sensory domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
52374,52540
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
81296,51445
81296 - E set domains
51445 - (Trans)glycosidases | 0 | Direct |
52540,51569
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | Direct |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,47473
56112 - Protein kinase-like (PK-like)
47473 - EF-hand | 0 | Direct |
52374,82114
52374 - Nucleotidylyl transferase
82114 - Riboflavin kinase-like | 0 | Direct |
57850,57667
57850 - RING/U-box
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
52540,47648
52540 - P-loop containing nucleoside triphosphate hydrolases
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
49599,50156
49599 - TRAF domain-like
50156 - PDZ domain-like | 0 | Direct |
53155,46767
53155 - Methylated DNA-protein cysteine methyltransferase domain
46767 - Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | Direct |
55608,56672
55608 - Homing endonucleases
56672 - DNA/RNA polymerases | 0 | Direct |
56112,57850
56112 - Protein kinase-like (PK-like)
57850 - RING/U-box | 0 | Direct |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | Direct |
161245,57850
161245 - Zinc hairpin stack
57850 - RING/U-box | 0 | Direct |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
81593,81891
81593 - Nucleotidyltransferase substrate binding subunit/domain
81891 - Poly A polymerase C-terminal region-like | 0 | Direct |
88697,52374
88697 - PUA domain-like
52374 - Nucleotidylyl transferase | 0 | Direct |
56112,52799
56112 - Protein kinase-like (PK-like)
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
56112,50998
56112 - Protein kinase-like (PK-like)
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
82199,81822
82199 - SET domain
81822 - RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
55666,46915
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
81296,54001
81296 - E set domains
54001 - Cysteine proteinases | 0 | Direct |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
68906,57850
68906 - SAP domain
57850 - RING/U-box | 0 | Direct |
56219,56672
56219 - DNase I-like
56672 - DNA/RNA polymerases | 0 | Direct |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | Direct |
90229,90229
90229 - CCCH zinc finger
90229 - CCCH zinc finger | 0 | Direct |
53300,57850
53300 - vWA-like
57850 - RING/U-box | 0 | Direct |
50800,51621
50800 - PK beta-barrel domain-like
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
56784,52540
56784 - HAD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47807,53098
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like | 0 | Direct |
158472,55785
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
117839,117839
117839 - WWE domain
117839 - WWE domain | 0 | Direct |
55083,51717
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
51717 - Dihydropteroate synthetase-like | 0 | Direct |
52518,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
57884,46689
57884 - Ada DNA repair protein, N-terminal domain (N-Ada 10)
46689 - Homeodomain-like | 0 | Direct |
51726,51726
51726 - UROD/MetE-like
51726 - UROD/MetE-like | 0 | Direct |
52151,51412
52151 - FabD/lysophospholipase-like
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
52172,55785
52172 - CheY-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
52949,52540
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
64484,-9
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
-9 - PDB | 0 | Direct |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
47212,56112
47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55781,47384
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
48452,140931
48452 - TPR-like
140931 - Fic-like | 0 | Direct |
47648,52418
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
53474,53335
53474 - alpha/beta-Hydrolases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | Direct |
51230,51230
51230 - Single hybrid motif
51230 - Single hybrid motif | 0 | Direct |
63882,53218
63882 - MoeA N-terminal region -like
53218 - Molybdenum cofactor biosynthesis proteins | 0 | Direct |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | Direct |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
53474,54631
53474 - alpha/beta-Hydrolases
54631 - CBS-domain pair | 0 | Direct |
55205,52540
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53790,53335
53790 - Tetrapyrrole methylase
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
56112,52540
56112 - Protein kinase-like (PK-like)
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | Direct |
50037,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | Direct |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
53098,53098
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | Direct |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | Direct |
56112,50044
56112 - Protein kinase-like (PK-like)
50044 - SH3-domain | 0 | Direct |
52799,56091
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
55804,52794
55804 - Phoshotransferase/anion transport protein
52794 - PTS system IIB component-like | 0 | Direct |
88697,75217
88697 - PUA domain-like
75217 - alpha/beta knot | 0 | Direct |
47986,56112
47986 - DEATH domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,48403
56112 - Protein kinase-like (PK-like)
48403 - Ankyrin repeat | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
56112,50978
56112 - Protein kinase-like (PK-like)
50978 - WD40 repeat-like | 0 | Direct |
158472,47384
158472 - HAMP domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
53335,53335
53335 - S-adenosyl-L-methionine-dependent methyltransferases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0 | Direct |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
102114,53383
102114 - Radical SAM enzymes
53383 - PLP-dependent transferases | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
52821,52821
52821 - Rhodanese/Cell cycle control phosphatase
52821 - Rhodanese/Cell cycle control phosphatase | 0 | Direct |
55116,101262
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
101262 - Methenyltetrahydrofolate cyclohydrolase-like | 0 | Direct |
47836,47943
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
55890,55874
55890 - Sporulation response regulatory protein Spo0B
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
64484,64484
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
54001,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
53850,54913
53850 - Periplasmic binding protein-like II
54913 - GlnB-like | 0 | Direct |
48403,47769
48403 - Ankyrin repeat
47769 - SAM/Pointed domain | 0 | Direct |
53613,52374
53613 - Ribokinase-like
52374 - Nucleotidylyl transferase | 0 | Direct |
54277,56112
54277 - CAD & PB1 domains
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | Direct |
109604,55021
109604 - HD-domain/PDEase-like
55021 - ACT-like | 0 | Direct |
54160,82199
54160 - Chromo domain-like
82199 - SET domain | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
88798,50249
88798 - N-terminal, heterodimerisation domain of RBP7 (RpoE)
50249 - Nucleic acid-binding proteins | 0 | Direct |
51197,53335
51197 - Clavaminate synthase-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
52540,53271
52540 - P-loop containing nucleoside triphosphate hydrolases
53271 - PRTase-like | 0 | Direct |
53328,50486
53328 - Formyltransferase
50486 - FMT C-terminal domain-like | 0 | Direct |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | Direct |
50249,89550
50249 - Nucleic acid-binding proteins
89550 - PHP domain-like | 0 | Direct |
46689,53697
46689 - Homeodomain-like
53697 - SIS domain | 0 | Direct |
54160,53335
54160 - Chromo domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
52047,56112
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
51621,52935
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like | 0 | Direct |
54197,54197
54197 - HIT-like
54197 - HIT-like | 0 | Direct |
69593,56801
69593 - Glycerol-3-phosphate (1)-acyltransferase
56801 - Acetyl-CoA synthetase-like | 0 | Direct |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | Direct |
88697,53335
88697 - PUA domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | Direct |
51735,75615
51735 - NAD(P)-binding Rossmann-fold domains
75615 - Siroheme synthase middle domains-like | 0 | Direct |
57850,101898
57850 - RING/U-box
101898 - NHL repeat | 0 | Direct |
54277,57889
54277 - CAD & PB1 domains
57889 - Cysteine-rich domain | 0 | Direct |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55874,52172
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like | 0 | Direct |
57850,50978
57850 - RING/U-box
50978 - WD40 repeat-like | 0 | Direct |
50249,56300
50249 - Nucleic acid-binding proteins
56300 - Metallo-dependent phosphatases | 0 | Direct |
56672,90234
56672 - DNA/RNA polymerases
90234 - Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
57953,49599
57953 - Trimerization domain of TRAF
49599 - TRAF domain-like | 0 | Direct |
90209,57850
90209 - Ran binding protein zinc finger-like
57850 - RING/U-box | 0 | Direct |
50044,53335
50044 - SH3-domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
55550,57850
55550 - SH2 domain
57850 - RING/U-box | 0 | Direct |
55729,47370
55729 - Acyl-CoA N-acyltransferases (Nat)
47370 - Bromodomain | 0 | Direct |
55073,56112
55073 - Nucleotide cyclase
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53850,55785
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
56112,116846
56112 - Protein kinase-like (PK-like)
116846 - MIT domain | 0 | Direct |
55973,55973
55973 - S-adenosylmethionine synthetase
55973 - S-adenosylmethionine synthetase | 0 | Direct |
55781,55874
55781 - GAF domain-like
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
52172,47226
52172 - CheY-like
47226 - Histidine-containing phosphotransfer domain, HPT domain | 0 | Direct |
56672,46919
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | Direct |
47226,55052
47226 - Histidine-containing phosphotransfer domain, HPT domain
55052 - CheY-binding domain of CheA | 0 | Direct |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | Direct |
57850,57845
57850 - RING/U-box
57845 - B-box zinc-binding domain | 0 | Direct |
48013,53335
48013 - NusB-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
56112,48452
56112 - Protein kinase-like (PK-like)
48452 - TPR-like | 0 | Direct |
52540,52402
52540 - P-loop containing nucleoside triphosphate hydrolases
52402 - Adenine nucleotide alpha hydrolases-like | 0 | Direct |
52418,54680
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
54680 - Pyrimidine nucleoside phosphorylase C-terminal domain | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | Direct |
55116,55116
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 0 | Direct |
52113,142921
52113 - BRCT domain
142921 - WGR domain-like | 0 | Direct |
51569,51269
51569 - Aldolase
51269 - AFP III-like domain | 0 | Direct |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
57850,117839
57850 - RING/U-box
117839 - WWE domain | 0 | Direct |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | Direct |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | Direct |
75217,54593
75217 - alpha/beta knot
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
53335,53383
53335 - S-adenosyl-L-methionine-dependent methyltransferases
53383 - PLP-dependent transferases | 0 | Direct |
75217,109604
75217 - alpha/beta knot
109604 - HD-domain/PDEase-like | 0 | Direct |
53448,69765
53448 - Nucleotide-diphospho-sugar transferases
69765 - IpsF-like | 0 | Direct |
51110,51110
51110 - alpha-D-mannose-specific plant lectins
51110 - alpha-D-mannose-specific plant lectins | 0 | Direct |
53448,50370
53448 - Nucleotide-diphospho-sugar transferases
50370 - Ricin B-like lectins | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
56796,55205
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like | 0 | Direct |
57783,47954
57783 - Zinc beta-ribbon
47954 - Cyclin-like | 0 | Direct |
143437,53335
143437 - THUMP domain-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
51621,55804
51621 - Phosphoenolpyruvate/pyruvate domain
55804 - Phoshotransferase/anion transport protein | 0 | Direct |
47005,52777
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
52777 - CoA-dependent acyltransferases | 0 | Direct |
51391,53613
51391 - Thiamin phosphate synthase
53613 - Ribokinase-like | 0 | Direct |
53335,50249
53335 - S-adenosyl-L-methionine-dependent methyltransferases
50249 - Nucleic acid-binding proteins | 0 | Direct |
53218,63867
53218 - Molybdenum cofactor biosynthesis proteins
63867 - MoeA C-terminal domain-like | 0 | Direct |
55594,47831
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
49562,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
69593,47473
69593 - Glycerol-3-phosphate (1)-acyltransferase
47473 - EF-hand | 0 | Direct |
52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | Direct |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0 | Direct |
54495,46934
54495 - UBC-like
46934 - UBA-like | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56042,53328
56042 - PurM C-terminal domain-like
53328 - Formyltransferase | 0 | Direct |
49879,57850
49879 - SMAD/FHA domain
57850 - RING/U-box | 0 | Direct |
55931,48034
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain | 0 | Direct |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
50729,69322
50729 - PH domain-like
69322 - Tricorn protease domain 2 | 0 | Direct |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | Direct |
57440,56112
57440 - Kringle-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53448,53448
53448 - Nucleotide-diphospho-sugar transferases
53448 - Nucleotide-diphospho-sugar transferases | 0 | Direct |
57774,52540
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
50486,51735
50486 - FMT C-terminal domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
52833,47384
52833 - Thioredoxin-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
55785,55781
55785 - PYP-like sensor domain (PAS domain)
55781 - GAF domain-like | 0 | Direct |
54791,50249
54791 - Eukaryotic type KH-domain (KH-domain type I)
50249 - Nucleic acid-binding proteins | 0 | Direct |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | Direct |
56214,56214
56214 - 4'-phosphopantetheinyl transferase
56214 - 4'-phosphopantetheinyl transferase | 0 | Direct |
101288,101288
101288 - L27 domain
101288 - L27 domain | 0 | Direct |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53756,53756
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53756 - UDP-Glycosyltransferase/glycogen phosphorylase | 0 | Direct |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | Direct |
46585,49562
46585 - HR1 repeat
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57903,57850
57903 - FYVE/PHD zinc finger
57850 - RING/U-box | 0 | Direct |
63570,56204
63570 - PABC (PABP) domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
52210,51735
52210 - Succinyl-CoA synthetase domains
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
47413,53335
47413 - lambda repressor-like DNA-binding domains
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
63999,63862
63999 - Thiamin pyrophosphokinase, catalytic domain
63862 - Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
55785,55890
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B | 0 | Direct |
47802,81585
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like | 0 | Direct |
51717,47644
51717 - Dihydropteroate synthetase-like
47644 - Methionine synthase domain | 0 | Direct |
103190,158472
103190 - Sensory domain-like
158472 - HAMP domain-like | 0 | Direct |
48452,57850
48452 - TPR-like
57850 - RING/U-box | 0 | Direct |
53633,53720
53633 - Carbamate kinase-like
53720 - ALDH-like | 0 | Direct |
55785,47384
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
81301,47473
81301 - Nucleotidyltransferase
47473 - EF-hand | 0 | Direct |
57716,50156
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like | 0 | Direct |
52335,53927
52335 - Methylglyoxal synthase-like
53927 - Cytidine deaminase-like | 0 | Direct |
54637,52151
54637 - Thioesterase/thiol ester dehydrase-isomerase
52151 - FabD/lysophospholipase-like | 0 | Direct |
49599,57953
49599 - TRAF domain-like
57953 - Trimerization domain of TRAF | 0 | Direct |
81301,81593
81301 - Nucleotidyltransferase
81593 - Nucleotidyltransferase substrate binding subunit/domain | 0 | Direct |
-9,-7
-9 - PDB
-7 - CATH | 0 | Direct |
81631,81301
81631 - PAP/OAS1 substrate-binding domain
81301 - Nucleotidyltransferase | 0 | Direct |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
52540,57802
52540 - P-loop containing nucleoside triphosphate hydrolases
57802 - Rubredoxin-like | 0 | Direct |
52794,52794
52794 - PTS system IIB component-like
52794 - PTS system IIB component-like | 0 | Direct |
57850,49599
57850 - RING/U-box
49599 - TRAF domain-like | 0 | Direct |
56112,50985
56112 - Protein kinase-like (PK-like)
50985 - RCC1/BLIP-II | 0 | Direct |
56112,64268
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | Direct |
48452,53335
48452 - TPR-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
53271,53271
53271 - PRTase-like
53271 - PRTase-like | 0 | Direct |
53067,56112
53067 - Actin-like ATPase domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
54236,90209
54236 - Ubiquitin-like
90209 - Ran binding protein zinc finger-like | 0 | Direct |
51735,48256
51735 - NAD(P)-binding Rossmann-fold domains
48256 - Citrate synthase | 0 | Direct |
50249,53335
50249 - Nucleic acid-binding proteins
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
55729,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
55088,48081
55088 - Methyl-coenzyme M reductase subunits
48081 - Methyl-coenzyme M reductase alpha and beta chain C-terminal domain | 0 | Direct |
52317,47648
52317 - Class I glutamine amidotransferase-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
56235,53697
56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
53697 - SIS domain | 0 | Direct |
53756,53067
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53067 - Actin-like ATPase domain | 0 | Direct |
46785,56112
46785 - "Winged helix" DNA-binding domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81296,101898
81296 - E set domains
101898 - NHL repeat | 0 | Direct |
48403,57850
48403 - Ankyrin repeat
57850 - RING/U-box | 0 | Direct |
56112,90257
56112 - Protein kinase-like (PK-like)
90257 - Myosin rod fragments | 0 | Direct |
46785,82114
46785 - "Winged helix" DNA-binding domain
82114 - Riboflavin kinase-like | 0 | Direct |
49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | Direct |
52540,75138
52540 - P-loop containing nucleoside triphosphate hydrolases
75138 - HprK N-terminal domain-like | 0 | Direct |
143724,56024
143724 - PHP14-like
56024 - Phospholipase D/nuclease | 0 | Direct |
53062,55594
53062 - PTS system fructose IIA component-like
55594 - HPr-like | 0 | Direct |
103025,101790
103025 - Folate-binding domain
101790 - Aminomethyltransferase beta-barrel domain | 0 | Direct |
53955,56601
53955 - Lysozyme-like
56601 - beta-lactamase/transpeptidase-like | 0 | Direct |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
52317,56322
52317 - Class I glutamine amidotransferase-like
56322 - ADC synthase | 0 | Direct |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | Direct |
52009,51621
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | Direct |
143437,52402
143437 - THUMP domain-like
52402 - Adenine nucleotide alpha hydrolases-like | 0 | Direct |
64268,49562
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
46785,57903
46785 - "Winged helix" DNA-binding domain
57903 - FYVE/PHD zinc finger | 0 | Direct |
53901,55718
53901 - Thiolase-like
55718 - SCP-like | 0 | Direct |
55154,56091
55154 - CYTH-like phosphatases
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | Direct |
56672,55608
56672 - DNA/RNA polymerases
55608 - Homing endonucleases | 0 | Direct |
88802,88697
88802 - Pre-PUA domain
88697 - PUA domain-like | 0 | Direct |
75217,75217
75217 - alpha/beta knot
75217 - alpha/beta knot | 0 | Direct |
50998,56112
50998 - Quinoprotein alcohol dehydrogenase-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57850,48371
57850 - RING/U-box
48371 - ARM repeat | 0 | Direct |
54919,54919
54919 - Nucleoside diphosphate kinase, NDK
54919 - Nucleoside diphosphate kinase, NDK | 0 | Direct |
50965,52540
50965 - Galactose oxidase, central domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
116846,116846
116846 - MIT domain
116846 - MIT domain | 0 | Direct |
48371,117839
48371 - ARM repeat
117839 - WWE domain | 0 | Direct |
49899,56112
49899 - Concanavalin A-like lectins/glucanases
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49785,50985
49785 - Galactose-binding domain-like
50985 - RCC1/BLIP-II | 0 | Direct |
50156,56112
50156 - PDZ domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56672,51294
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
56112,54928
56112 - Protein kinase-like (PK-like)
54928 - RNA-binding domain, RBD | 0 | Direct |
52151,55048
52151 - FabD/lysophospholipase-like
55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0 | Direct |
52087,46966
52087 - CRAL/TRIO domain
46966 - Spectrin repeat | 0 | Direct |
55112,55112
55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase
55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
82549,101473
82549 - DAK1/DegV-like
101473 - DhaL-like | 0 | Direct |
140356,143724
140356 - PPK N-terminal domain-like
143724 - PHP14-like | 0 | Direct |
49562,48350
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | Direct |
57850,57933
57850 - RING/U-box
57933 - TAZ domain | 0 | Direct |
53448,51182
53448 - Nucleotide-diphospho-sugar transferases
51182 - RmlC-like cupins | 0 | Direct |
49785,159034
49785 - Galactose-binding domain-like
159034 - Mib/herc2 domain-like | 0 | Direct |
75615,53790
75615 - Siroheme synthase middle domains-like
53790 - Tetrapyrrole methylase | 0 | Direct |
52833,47616
52833 - Thioredoxin-like
47616 - GST C-terminal domain-like | 0 | Direct |
51294,56672
51294 - Hedgehog/intein (Hint) domain
56672 - DNA/RNA polymerases | 0 | Direct |
53850,54782
53850 - Periplasmic binding protein-like II
54782 - Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 0 | Direct |
52794,55804
52794 - PTS system IIB component-like
55804 - Phoshotransferase/anion transport protein | 0 | Direct |
47757,53335
47757 - Chemotaxis receptor methyltransferase CheR, N-terminal domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
57850,159034
57850 - RING/U-box
159034 - Mib/herc2 domain-like | 0 | Direct |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | Direct |
81585,81301
81585 - PsbU/PolX domain-like
81301 - Nucleotidyltransferase | 0 | Direct |
47644,52242
47644 - Methionine synthase domain
52242 - Cobalamin (vitamin B12)-binding domain | 0 | Direct |
81995,56112
81995 - beta-sandwich domain of Sec23/24
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | Direct |
47769,56399
47769 - SAM/Pointed domain
56399 - ADP-ribosylation | 0 | Direct |
49309,49309
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | Direct |
51569,54909
51569 - Aldolase
54909 - Dimeric alpha+beta barrel | 0 | Direct |
54495,57850
54495 - UBC-like
57850 - RING/U-box | 0 | Direct |
161219,161245
161219 - CHY zinc finger-like
161245 - Zinc hairpin stack | 0 | Direct |
50465,52540
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
159034,57850
159034 - Mib/herc2 domain-like
57850 - RING/U-box | 0 | Direct |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
142921,47587
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | Direct |
46785,53335
46785 - "Winged helix" DNA-binding domain
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
55257,47789
55257 - RBP11-like subunits of RNA polymerase
47789 - C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
52242,56507
52242 - Cobalamin (vitamin B12)-binding domain
56507 - Methionine synthase activation domain-like | 0 | Direct |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | Direct |
52058,56112
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
46589,55729
46589 - tRNA-binding arm
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
141673,50800
141673 - MOSC N-terminal domain-like
50800 - PK beta-barrel domain-like | 0 | Direct |
55666,54791
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
57889,111331
57889 - Cysteine-rich domain
111331 - NAD kinase/diacylglycerol kinase-like | 0 | Direct |
54236,56112
54236 - Ubiquitin-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 0 | Direct |
53633,55021
53633 - Carbamate kinase-like
55021 - ACT-like | 0 | Direct |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
53335,50965
53335 - S-adenosyl-L-methionine-dependent methyltransferases
50965 - Galactose oxidase, central domain | 0 | Direct |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | Direct |
47587,56399
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | Direct |
75138,53659
75138 - HprK N-terminal domain-like
53659 - Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
55874,50341
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
50341 - CheW-like | 0 | Direct |
53448,52266
53448 - Nucleotide-diphospho-sugar transferases
52266 - SGNH hydrolase | 0 | Direct |
56553,55257
56553 - Insert subdomain of RNA polymerase alpha subunit
55257 - RBP11-like subunits of RNA polymerase | 0 | Direct |
-9,51569
-9 - PDB
51569 - Aldolase | 0 | Direct |
48403,52113
48403 - Ankyrin repeat
52113 - BRCT domain | 0 | Direct |
52402,52821
52402 - Adenine nucleotide alpha hydrolases-like
52821 - Rhodanese/Cell cycle control phosphatase | 0 | Direct |
55620,55083
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53633,55729
53633 - Carbamate kinase-like
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
49265,63825
49265 - Fibronectin type III
63825 - YWTD domain | 0 | Direct |
55729,46589
55729 - Acyl-CoA N-acyltransferases (Nat)
46589 - tRNA-binding arm | 0 | Direct |
51735,52540
51735 - NAD(P)-binding Rossmann-fold domains
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
56112,103243
56112 - Protein kinase-like (PK-like)
103243 - KA1-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
51569,53223
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
48371,48403
48371 - ARM repeat
48403 - Ankyrin repeat | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
47807,56672
47807 - 5' to 3' exonuclease, C-terminal subdomain
56672 - DNA/RNA polymerases | 0 | Direct |
53448,56784
53448 - Nucleotide-diphospho-sugar transferases
56784 - HAD-like | 0 | Direct |
89550,53098
89550 - PHP domain-like
53098 - Ribonuclease H-like | 0 | Direct |
51230,47005
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | Direct |
52540,57774
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
50965,51197
50965 - Galactose oxidase, central domain
51197 - Clavaminate synthase-like | 0 | Direct |
55021,51735
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,57716
52540 - P-loop containing nucleoside triphosphate hydrolases
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
55052,47384
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
49265,49899
49265 - Fibronectin type III
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
55781,55785
55781 - GAF domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
63825,49265
63825 - YWTD domain
49265 - Fibronectin type III | 0 | Direct |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | Direct |
69360,51445
69360 - Cell wall binding repeat
51445 - (Trans)glycosidases | 0 | Direct |
52540,55729
52540 - P-loop containing nucleoside triphosphate hydrolases
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
56112,48726
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin | 0 | Direct |
48439,49594
48439 - Protein prenylyltransferase
49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain | 0 | Direct |
52540,88697
52540 - P-loop containing nucleoside triphosphate hydrolases
88697 - PUA domain-like | 0 | Direct |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | Direct |
53633,88697
53633 - Carbamate kinase-like
88697 - PUA domain-like | 0 | Direct |
103190,55785
103190 - Sensory domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
89837,89837
89837 - Doublecortin (DC)
89837 - Doublecortin (DC) | 0 | Direct |
50692,47648
50692 - ADC-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
53597,55831
53597 - Dihydrofolate reductase-like
55831 - Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
56037,53271
56037 - PheT/TilS domain
53271 - PRTase-like | 0 | Direct |
54928,51197
54928 - RNA-binding domain, RBD
51197 - Clavaminate synthase-like | 0 | Direct |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
63380,63380
63380 - Riboflavin synthase domain-like
63380 - Riboflavin synthase domain-like | 0 | Direct |
47831,52009
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain | 0 | Direct |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | Direct |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
103473,53335
103473 - MFS general substrate transporter
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
51569,47473
51569 - Aldolase
47473 - EF-hand | 0 | Direct |
90229,57850
90229 - CCCH zinc finger
57850 - RING/U-box | 0 | Direct |
64268,56112
64268 - PX domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52113,47802
52113 - BRCT domain
47802 - DNA polymerase beta, N-terminal domain-like | 0 | Direct |
81631,57756
81631 - PAP/OAS1 substrate-binding domain
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
53271,51366
53271 - PRTase-like
51366 - Ribulose-phoshate binding barrel | 0 | Direct |
46915,54211
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
47473,55550
47473 - EF-hand
55550 - SH2 domain | 0 | Direct |
52540,81301
52540 - P-loop containing nucleoside triphosphate hydrolases
81301 - Nucleotidyltransferase | 0 | Direct |
51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0 | Direct |
54593,53784
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
53784 - Phosphofructokinase | 0 | Direct |
47592,90209
47592 - SWIB/MDM2 domain
90209 - Ran binding protein zinc finger-like | 0 | Direct |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | Direct |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | Direct |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57667,54928
57667 - beta-beta-alpha zinc fingers
54928 - RNA-binding domain, RBD | 0 | Direct |
51713,88802
51713 - tRNA-guanine transglycosylase
88802 - Pre-PUA domain | 0 | Direct |
49594,52075
49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
52075 - Outer arm dynein light chain 1 | 0 | Direct |
89000,110921
89000 - post-HMGL domain-like
110921 - 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | Direct |
117281,51197
117281 - Kelch motif
51197 - Clavaminate synthase-like | 0 | Direct |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49599,160088
49599 - TRAF domain-like
160088 - NRDP1 C-terminal domain-like | 0 | Direct |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | Direct |
52935,52009
52935 - PK C-terminal domain-like
52009 - Phosphohistidine domain | 0 | Direct |
54160,55729
54160 - Chromo domain-like
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
55021,55021
55021 - ACT-like
55021 - ACT-like | 0 | Direct |
56112,55681
56112 - Protein kinase-like (PK-like)
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81891,109604
81891 - Poly A polymerase C-terminal region-like
109604 - HD-domain/PDEase-like | 0 | Direct |
47391,52540
47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47384,55874
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
56059,52009
56059 - Glutathione synthetase ATP-binding domain-like
52009 - Phosphohistidine domain | 0 | Direct |
47668,47473
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand | 0 | Direct |
57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | Direct |
53613,51391
53613 - Ribokinase-like
51391 - Thiamin phosphate synthase | 0 | Direct |
52172,52172
52172 - CheY-like
52172 - CheY-like | 0 | Direct |
53335,51905
53335 - S-adenosyl-L-methionine-dependent methyltransferases
51905 - FAD/NAD(P)-binding domain | 0 | Direct |
49562,51045
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
51045 - WW domain | 0 | Direct |
51045,56204
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | Direct |
53335,81799
53335 - S-adenosyl-L-methionine-dependent methyltransferases
81799 - Putative methyltransferase TM0872, insert domain | 0 | Direct |
52518,52467
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain | 0.000000000000001409 | Direct |
52467,52518
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 0.000000000000001409 | Direct |
52777,52777
52777 - CoA-dependent acyltransferases
52777 - CoA-dependent acyltransferases | 0.000000000000007509 | Direct |
88723,47807
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain | 0.0000000000001074 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.0000000000006475 | Direct |
52047,52058
52047 - RNI-like
52058 - L domain-like | 0.000000000004556 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0.00000000007955 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.00000000007955 | Direct |
51735,51735
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.0000000005044 | Direct |
109604,81301
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase | 0.00000001393 | Direct |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0.00000002213 | Direct |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0.0000001498 | Direct |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0.0000002024 | Direct |
51011,81296
51011 - Glycosyl hydrolase domain
81296 - E set domains | 0.0000002024 | Direct |
81296,49452
81296 - E set domains
49452 - Starch-binding domain-like | 0.0000002024 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0.0000007907 | Direct |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0.000001393 | Direct |
51206,56112
51206 - cAMP-binding domain-like
56112 - Protein kinase-like (PK-like) | 0.000003736 | Direct |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0.000004246 | Direct |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0.000005442 | Direct |
81301,81271
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.000006691 | Direct |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0.000009861 | Direct |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.00003311 | Direct |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0.00006854 | Direct |
47336,53474
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.00006854 | Direct |
74650,48208
74650 - Galactose mutarotase-like
48208 - Six-hairpin glycosidases | 0.00007426 | Direct |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0.00009991 | Direct |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.0002522 | Direct |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0.0003719 | Direct |
-9,-9
-9 - PDB
-9 - PDB | 0.0004755 | Direct |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.0008354 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.002445 | Inherited |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.002532 | Inherited |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.002788 | Inherited |
52374,52374
52374 - Nucleotidylyl transferase
52374 - Nucleotidylyl transferase | 0.00533 | Inherited |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0.006099 | Inherited |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.006099 | Inherited |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.006099 | Inherited |
51445,69360
51445 - (Trans)glycosidases
69360 - Cell wall binding repeat | 0.006582 | Inherited |
69360,69360
69360 - Cell wall binding repeat
69360 - Cell wall binding repeat | 0.006582 | Inherited |
53335,51735
53335 - S-adenosyl-L-methionine-dependent methyltransferases
51735 - NAD(P)-binding Rossmann-fold domains | 0.008695 | Inherited |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0.009161 | Inherited |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0.01334 | Inherited |
51246,55326
51246 - Rudiment single hybrid motif
55326 - PurM N-terminal domain-like | 0.02227 | Inherited |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.0223 | Inherited |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0.02289 | Inherited |
51690,-9
51690 - Nicotinate/Quinolinate PRTase C-terminal domain-like
-9 - PDB | 0.02289 | Inherited |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.05243 | Inherited |
57756,51283
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0.07349 | Inherited |
51283,50630
51283 - dUTPase-like
50630 - Acid proteases | 0.07349 | Inherited |
55785,55073
55785 - PYP-like sensor domain (PAS domain)
55073 - Nucleotide cyclase | 0.07873 | Inherited |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.1221 | Inherited |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0.154 | Inherited |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.1641 | Inherited |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0.3814 | Inherited |
55681,50037
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors | 0.3814 | Inherited |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.4464 | Inherited |
46626,46626
46626 - Cytochrome c
46626 - Cytochrome c | 0.471 | Inherited |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.4931 | Inherited |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.5346 | Inherited |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.6922 | Inherited |
47336,52777
47336 - ACP-like
52777 - CoA-dependent acyltransferases | 0.7138 | Inherited |
52096,52096
52096 - ClpP/crotonase
52096 - ClpP/crotonase | 0.7712 | Inherited |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.7872 | Inherited |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.9324 | Inherited |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 1 | Inherited |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 1 | Inherited |
82829,56037
82829 - MesJ substrate recognition domain-like
56037 - PheT/TilS domain | 1 | Inherited |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 1 | Inherited |
55620,55620
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55620 - Tetrahydrobiopterin biosynthesis enzymes-like | 1 | Inherited |
51971,54373
51971 - Nucleotide-binding domain
54373 - FAD-linked reductases, C-terminal domain | 1 | Inherited |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 1 | Inherited |
50249,55681
50249 - Nucleic acid-binding proteins
55681 - Class II aaRS and biotin synthetases | 1 | Inherited |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 1 | Inherited |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 1 | Inherited |
56176,55103
56176 - FAD-binding/transporter-associated domain-like
55103 - FAD-linked oxidases, C-terminal domain | 1 | Inherited |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 1 | Inherited |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | Inherited |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | Inherited |
56042,55326
56042 - PurM C-terminal domain-like
55326 - PurM N-terminal domain-like | 1 | Inherited |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 1 | Inherited |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | Inherited |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 1 | Inherited |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 1 | Inherited |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 1 | Inherited |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 1 | Inherited |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
53383,53383
53383 - PLP-dependent transferases
53383 - PLP-dependent transferases | 1 | Inherited |
52402,82829
52402 - Adenine nucleotide alpha hydrolases-like
82829 - MesJ substrate recognition domain-like | 1 | Inherited |
51905,54373
51905 - FAD/NAD(P)-binding domain
54373 - FAD-linked reductases, C-terminal domain | 1 | Inherited |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 1 | Inherited |
51735,50129
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like | 1 | Inherited |
54675,51690
54675 - Nicotinate/Quinolinate PRTase N-terminal domain-like
51690 - Nicotinate/Quinolinate PRTase C-terminal domain-like | 1 | Inherited |
54368,55931
54368 - Glutamine synthetase, N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 1 | Inherited |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
51569,89000
51569 - Aldolase
89000 - post-HMGL domain-like | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (Not in SPEC)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52058,52047,52058
52058 - L domain-like
52047 - RNI-like
52058 - L domain-like | 0 | DIRECT |
48065,50729,50044
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
89043,50494,56672
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
47031,50729,55550
47031 - Second domain of FERM
50729 - PH domain-like
55550 - SH2 domain | 0 | DIRECT |
50447,50465,52540
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
81296,54001,49309
81296 - E set domains
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
50729,50044,55550
50729 - PH domain-like
50044 - SH3-domain
55550 - SH2 domain | 0 | DIRECT |
53901,53901,55718
53901 - Thiolase-like
53901 - Thiolase-like
55718 - SCP-like | 0 | DIRECT |
57850,57850,57933
57850 - RING/U-box
57850 - RING/U-box
57933 - TAZ domain | 0 | DIRECT |
52113,142921,47587
52113 - BRCT domain
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase | 0 | DIRECT |
57924,57924,57924
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat
57924 - Inhibitor of apoptosis (IAP) repeat | 0 | DIRECT |
55681,50037,53067
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | DIRECT |
52540,51569,53223
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
51569,89000,110921
51569 - Aldolase
89000 - post-HMGL domain-like
110921 - 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 0 | DIRECT |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
51230,51230,47005
51230 - Single hybrid motif
51230 - Single hybrid motif
47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 0 | DIRECT |
55608,56672,51294
55608 - Homing endonucleases
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
55729,46589,55729
55729 - Acyl-CoA N-acyltransferases (Nat)
46589 - tRNA-binding arm
55729 - Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
55052,47384,55874
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
161219,161245,57850
161219 - CHY zinc finger-like
161245 - Zinc hairpin stack
57850 - RING/U-box | 0 | DIRECT |
57774,52540,57774
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
51283,46919,53098
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
57889,57889,111331
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
111331 - NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
51713,88802,88697
51713 - tRNA-guanine transglycosylase
88802 - Pre-PUA domain
88697 - PUA domain-like | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53098,56672,90234
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases
90234 - Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
50800,51621,52935
50800 - PK beta-barrel domain-like
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like | 0 | DIRECT |
55326,56042,53328
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like
53328 - Formyltransferase | 0 | DIRECT |
51735,50129,51735
51735 - NAD(P)-binding Rossmann-fold domains
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
46915,54211,55666
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
50630,56672,53098
50630 - Acid proteases
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | DIRECT |
81296,81296,51445
81296 - E set domains
81296 - E set domains
51445 - (Trans)glycosidases | 0 | DIRECT |
53850,53850,55785
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
51690,-9,-9
51690 - Nicotinate/Quinolinate PRTase C-terminal domain-like
-9 - PDB
-9 - PDB | 0 | DIRECT |
88723,47807,56672
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain
56672 - DNA/RNA polymerases | 0 | DIRECT |
52949,52540,52540
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,88697,52374
52540 - P-loop containing nucleoside triphosphate hydrolases
88697 - PUA domain-like
52374 - Nucleotidylyl transferase | 0 | DIRECT |
50630,56672,46919
50630 - Acid proteases
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
49599,49599,49599
49599 - TRAF domain-like
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
48097,56112,50729
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | DIRECT |
55666,46915,54211
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
143437,52402,52821
143437 - THUMP domain-like
52402 - Adenine nucleotide alpha hydrolases-like
52821 - Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
50044,48065,50729
50044 - SH3-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
142921,47587,56399
142921 - WGR domain-like
47587 - Domain of poly(ADP-ribose) polymerase
56399 - ADP-ribosylation | 0 | DIRECT |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
53098,56672,51294
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
49265,56112,48726
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin | 0 | DIRECT |
48034,55931,48034
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain | 0 | DIRECT |
50494,52540,89043
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
52540,57774,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51294,56672,55608
51294 - Hedgehog/intein (Hint) domain
56672 - DNA/RNA polymerases
55608 - Homing endonucleases | 0 | DIRECT |
54001,49309,49309
54001 - Cysteine proteinases
49309 - Transglutaminase, two C-terminal domains
49309 - Transglutaminase, two C-terminal domains | 0 | DIRECT |
52949,52540,56672
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
56672,53098,51283
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | DIRECT |
57850,49599,160088
57850 - RING/U-box
49599 - TRAF domain-like
160088 - NRDP1 C-terminal domain-like | 0 | DIRECT |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57889,49562,56112
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55785,55890,55874
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
47802,81585,81301
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like
81301 - Nucleotidyltransferase | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
50494,52540,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55620,55083,51717
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
51717 - Dihydropteroate synthetase-like | 0 | DIRECT |
52540,75138,53659
52540 - P-loop containing nucleoside triphosphate hydrolases
75138 - HprK N-terminal domain-like
53659 - Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
55205,52540,51569
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | DIRECT |
51445,69360,69360
51445 - (Trans)glycosidases
69360 - Cell wall binding repeat
69360 - Cell wall binding repeat | 0 | DIRECT |
56059,52210,51735
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
51735,47336,53474
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
52113,47802,81585
52113 - BRCT domain
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like | 0 | DIRECT |
103190,55785,55890
103190 - Sensory domain-like
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B | 0 | DIRECT |
47836,47943,47353
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | DIRECT |
55931,48034,55931
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
81301,81631,81301
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
81301 - Nucleotidyltransferase | 0 | DIRECT |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
49599,57953,49599
49599 - TRAF domain-like
57953 - Trimerization domain of TRAF
49599 - TRAF domain-like | 0 | DIRECT |
51197,52540,56672
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
57716,50156,56112
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53335,50965,51197
53335 - S-adenosyl-L-methionine-dependent methyltransferases
50965 - Galactose oxidase, central domain
51197 - Clavaminate synthase-like | 0 | DIRECT |
56553,55257,47789
56553 - Insert subdomain of RNA polymerase alpha subunit
55257 - RBP11-like subunits of RNA polymerase
47789 - C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
55785,47384,55874
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
57850,49599,49599
57850 - RING/U-box
49599 - TRAF domain-like
49599 - TRAF domain-like | 0 | DIRECT |
53062,55594,47831
53062 - PTS system fructose IIA component-like
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
-9,-9,-9
-9 - PDB
-9 - PDB
-9 - PDB | 0 | DIRECT |
52058,52058,56112
52058 - L domain-like
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50037,53067,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
54928,51197,53335
54928 - RNA-binding domain, RBD
51197 - Clavaminate synthase-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
53850,53850,56112
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
48371,56112,64268
48371 - ARM repeat
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | DIRECT |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | DIRECT |
52009,51621,55804
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain
55804 - Phoshotransferase/anion transport protein | 0 | DIRECT |
57184,52058,49265
57184 - Growth factor receptor domain
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
56672,53098,46919
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
47384,55874,52172
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like | 0 | DIRECT |
47353,57756,50630
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
101288,101288,50156
101288 - L27 domain
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
55666,54791,50249
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I)
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
158472,47384,55874
158472 - HAMP domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
82282,51717,47644
82282 - Homocysteine S-methyltransferase
51717 - Dihydropteroate synthetase-like
47644 - Methionine synthase domain | 0 | DIRECT |
56672,53098,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | DIRECT |
109604,55021,55021
109604 - HD-domain/PDEase-like
55021 - ACT-like
55021 - ACT-like | 0 | DIRECT |
51045,51045,51045
51045 - WW domain
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
63882,53218,63867
63882 - MoeA N-terminal region -like
53218 - Molybdenum cofactor biosynthesis proteins
63867 - MoeA C-terminal domain-like | 0 | DIRECT |
56672,52540,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50494,56672,88633
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
48403,52113,52113
48403 - Ankyrin repeat
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
90209,57850,57850
90209 - Ran binding protein zinc finger-like
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
-9,-7,56112
-9 - PDB
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53850,55785,47384
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
64484,-9,-9
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
-9 - PDB
-9 - PDB | 0 | DIRECT |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57850,49599,50156
57850 - RING/U-box
49599 - TRAF domain-like
50156 - PDZ domain-like | 0 | DIRECT |
56059,52009,51621
56059 - Glutathione synthetase ATP-binding domain-like
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
55021,51735,55347
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
52335,51556,51338
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
55785,55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
51621,52935,52009
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like
52009 - Phosphohistidine domain | 0 | DIRECT |
55874,52172,47226
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like
47226 - Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
52087,46966,46966
52087 - CRAL/TRIO domain
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
51569,53223,51735
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
52047,52047,52058
52047 - RNI-like
52047 - RNI-like
52058 - L domain-like | 0 | DIRECT |
47831,52009,51621
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
57716,57716,50156
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like | 0 | DIRECT |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
47384,55874,50341
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
50341 - CheW-like | 0 | DIRECT |
50729,57889,57889
50729 - PH domain-like
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
56112,101288,101288
56112 - Protein kinase-like (PK-like)
101288 - L27 domain
101288 - L27 domain | 0 | DIRECT |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
88723,47807,53098
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like | 0 | DIRECT |
88633,50494,52540
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52172,55785,47384
52172 - CheY-like
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
51045,51045,56204
51045 - WW domain
51045 - WW domain
56204 - Hect, E3 ligase catalytic domain | 0 | DIRECT |
54593,53784,53784
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | DIRECT |
56112,52799,49562
56112 - Protein kinase-like (PK-like)
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
56672,55608,56672
56672 - DNA/RNA polymerases
55608 - Homing endonucleases
56672 - DNA/RNA polymerases | 0 | DIRECT |
47031,50729,56112
47031 - Second domain of FERM
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54211,55666,54791
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
47473,47473,57889
47473 - EF-hand
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
56112,116846,116846
56112 - Protein kinase-like (PK-like)
116846 - MIT domain
116846 - MIT domain | 0 | DIRECT |
52317,47648,52418
52317 - Class I glutamine amidotransferase-like
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
50494,52540,56672
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
46785,57903,57903
46785 - "Winged helix" DNA-binding domain
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
47668,47473,55550
47668 - N-terminal domain of cbl (N-cbl)
47473 - EF-hand
55550 - SH2 domain | 0 | DIRECT |
48403,47769,56399
48403 - Ankyrin repeat
47769 - SAM/Pointed domain
56399 - ADP-ribosylation | 0 | DIRECT |
54236,90209,57850
54236 - Ubiquitin-like
90209 - Ran binding protein zinc finger-like
57850 - RING/U-box | 0 | DIRECT |
52518,52518,52922
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52922 - TK C-terminal domain-like | 0 | DIRECT |
158472,55785,47384
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
51283,50630,56672
51283 - dUTPase-like
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
52058,52047,56112
52058 - L domain-like
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56672,53098,50122
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
56059,52335,51556
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
51717,47644,52242
51717 - Dihydropteroate synthetase-like
| |
