|
Enzyme Commission (EC): Methyltransferases
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: EC Hierarchy (from IntEnz release 70)
Shortest distance to current term (+ for parents, - for children) |
EC term [EC ID] <#Children> |
(#SF|#FA) |
#Supra-domain (Single|Duplex|Triple) |
+ + + 3: | root [root] <7> |
+ + 2: | Transferases [2] <10> | (445|680) |
(444|535|275) |
+ 1: | Transferring one-carbon groups [2.1] <5> | (79|117) |
(79|68|26) |
0: | Methyltransferases [2.1.1] <378> | (59|94) |
(59|48|10) |
- 1: | (+)-6a-hydroxymaackiain 3-O-methyltransferase [2.1.1.270] | (0|0) |
(0|0|0) |
- 1: | (+)-O-methylkolavelool synthase [2.1.1.347] | (0|0) |
(0|0|0) |
- 1: | (-)-pluviatolide 4-O-methyltransferase [2.1.1.323] | (0|0) |
(0|0|0) |
- 1: | (Iso)eugenol O-methyltransferase [2.1.1.146] | (1|2) |
(1|1|0) |
- 1: | (NAD(P)H-oxidizing) [2.1.1.74] | (1|0) |
(1|0|0) |
- 1: | (R,S)-reticuline 7-O-methyltransferase [2.1.1.291] | (0|0) |
(0|0|0) |
- 1: | (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase [2.1.1.115] | (0|0) |
(0|0|0) |
- 1: | (RS)-norcoclaurine 6-O-methyltransferase [2.1.1.128] | (1|2) |
(1|1|0) |
- 1: | (S)-coclaurine-N-methyltransferase [2.1.1.140] | (0|0) |
(0|0|0) |
- 1: | (S)-scoulerine 9-O-methyltransferase [2.1.1.117] | (1|2) |
(1|1|0) |
- 1: | (S)-tetrahydroprotoberberine N-methyltransferase [2.1.1.122] | (0|1) |
(0|0|0) |
- 1: | 10-hydroxydihydrosanguinarine 10-O-methyltransferase [2.1.1.119] | (0|0) |
(0|0|0) |
- 1: | 12-hydroxydihydrochelirubine 12-O-methyltransferase [2.1.1.120] | (0|0) |
(0|0|0) |
- 1: | 16S rRNA (adenine(1408)-N(1))-methyltransferase [2.1.1.180] | (0|0) |
(0|0|0) |
- 1: | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase [2.1.1.182] | (1|1) |
(1|0|0) |
- 1: | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase [2.1.1.198] | (1|1) |
(1|0|0) |
- 1: | 16S rRNA (cytidine(1409)-2'-O)-methyltransferase [2.1.1.227] | (0|0) |
(0|0|0) |
- 1: | 16S rRNA (cytosine(1402)-N(4))-methyltransferase [2.1.1.199] | (2|2) |
(2|1|0) |
- 1: | 16S rRNA (cytosine(1407)-C(5))-methyltransferase [2.1.1.178] | (1|1) |
(1|0|0) |
- 1: | 16S rRNA (cytosine(967)-C(5))-methyltransferase [2.1.1.176] | (2|2) |
(2|1|0) |
- 1: | 16S rRNA (guanine(1207)-N(2))-methyltransferase [2.1.1.172] | (1|1) |
(1|1|0) |
- 1: | 16S rRNA (guanine(1405)-N(7))-methyltransferase [2.1.1.179] | (0|0) |
(0|0|0) |
- 1: | 16S rRNA (guanine(1516)-N(2))-methyltransferase [2.1.1.242] | (1|1) |
(1|0|0) |
- 1: | 16S rRNA (guanine(527)-N(7))-methyltransferase [2.1.1.170] | (1|1) |
(1|0|0) |
- 1: | 16S rRNA (guanine(966)-N(2))-methyltransferase [2.1.1.171] | (0|1) |
(0|0|0) |
- 1: | 16S rRNA (uracil(1498)-N(3))-methyltransferase [2.1.1.193] | (2|2) |
(2|1|0) |
- 1: | 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase [2.1.1.183] | (0|1) |
(0|0|0) |
- 1: | 18S rRNA (guanine(1575)-N(7))-methyltransferase [2.1.1.309] | (0|0) |
(0|0|0) |
- 1: | 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase [2.1.1.241] | (0|0) |
(0|0|0) |
- 1: | 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase [2.1.1.212] | (1|2) |
(1|1|0) |
- 1: | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase [2.1.1.303] | (0|0) |
(0|0|0) |
- 1: | 2-ketoarginine methyltransferase [2.1.1.243] | (0|0) |
(0|0|0) |
- 1: | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [2.1.1.201] | (1|1) |
(1|0|0) |
- 1: | 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase [2.1.1.295] | (0|0) |
(0|0|0) |
- 1: | 2-polyprenyl-6-hydroxyphenol methylase [2.1.1.222] | (1|0) |
(1|0|0) |
- 1: | 21S rRNA (uridine(2791)-2'-O)-methyltransferase [2.1.1.168] | (0|0) |
(0|0|0) |
- 1: | 23S rRNA (adenine(1618)-N(6))-methyltransferase [2.1.1.181] | (1|1) |
(1|0|0) |
- 1: | 23S rRNA (adenine(2030)-N(6))-methyltransferase [2.1.1.266] | (0|0) |
(0|0|0) |
- 1: | 23S rRNA (adenine(2085)-N(6))-dimethyltransferase [2.1.1.184] | (0|1) |
(0|0|0) |
- 1: | 23S rRNA (adenine(2503)-C(2))-methyltransferase [2.1.1.192] | (1|1) |
(1|0|0) |
- 1: | 23S rRNA (adenine(2503)-C(8))-methyltransferase [2.1.1.224] | (1|0) |
(1|0|0) |
- 1: | 23S rRNA (adenosine(1067)-2'-O)-methyltransferase [2.1.1.230] | (1|1) |
(1|0|0) |
- 1: | 23S rRNA (cytidine(1920)-2'-O)-methyltransferase [2.1.1.226] | (0|0) |
(0|0|0) |
- 1: | 23S rRNA (cytidine(2498)-2'-O)-methyltransferase [2.1.1.186] | (1|1) |
(1|0|0) |
- 1: | 23S rRNA (cytosine(1962)-C(5))-methyltransferase [2.1.1.191] | (2|2) |
(2|1|0) |
- 1: | 23S rRNA (guanine(1835)-N(2))-methyltransferase [2.1.1.174] | (1|1) |
(1|0|0) |
- 1: | 23S rRNA (guanine(2069)-N(7))-methyltransferase [2.1.1.264] | (1|1) |
(1|1|0) |
- 1: | 23S rRNA (guanine(2445)-N(2))-methyltransferase [2.1.1.173] | (1|1) |
(1|1|0) |
- 1: | 23S rRNA (guanine(2535)-N(1))-methyltransferase [2.1.1.209] | (0|0) |
(0|0|0) |
- 1: | 23S rRNA (guanine(745)-N(1))-methyltransferase [2.1.1.187] | (0|0) |
(0|0|0) |
- 1: | 23S rRNA (guanine(748)-N(1))-methyltransferase [2.1.1.188] | (0|0) |
(0|0|0) |
- 1: | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase [2.1.1.185] | (2|2) |
(2|1|0) |
- 1: | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase [2.1.1.177] | (1|1) |
(1|0|0) |
- 1: | 23S rRNA (uracil(1939)-C(5))-methyltransferase [2.1.1.190] | (2|2) |
(2|1|0) |
- 1: | 23S rRNA (uracil(747)-C(5))-methyltransferase [2.1.1.189] | (1|1) |
(1|0|0) |
- 1: | 23S rRNA (uridine(2479)-2'-O)-methyltransferase [2.1.1.208] | (0|0) |
(0|0|0) |
- 1: | 23S rRNA (uridine(2552)-2'-O)-methyltransferase [2.1.1.166] | (1|1) |
(1|1|0) |
- 1: | 24-methylenesterol C-methyltransferase [2.1.1.143] | (0|0) |
(0|0|0) |
- 1: | 25S rRNA (adenine(2142)-N(1))-methyltransferase [2.1.1.286] | (0|0) |
(0|0|0) |
- 1: | 25S rRNA (adenine(645)-N(1))-methyltransferase [2.1.1.287] | (0|0) |
(0|0|0) |
- 1: | 25S rRNA (cytosine(2278)-C(5))-methyltransferase [2.1.1.311] | (0|0) |
(0|0|0) |
- 1: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase [2.1.1.310] | (0|0) |
(0|0|0) |
- 1: | 25S rRNA (uracil(2634)-N(3))-methyltransferase [2.1.1.313] | (0|0) |
(0|0|0) |
- 1: | 25S rRNA (uracil(2843)-N(3))-methyltransferase [2.1.1.312] | (0|0) |
(0|0|0) |
- 1: | 27-O-demethylrifamycin SV methyltransferase [2.1.1.315] | (0|0) |
(0|0|0) |
- 1: | 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase [2.1.1.167] | (0|0) |
(0|0|0) |
- 1: | 3'-demethylstaurosporine O-methyltransferase [2.1.1.139] | (0|0) |
(0|0|0) |
- 1: | 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase [2.1.1.116] | (1|2) |
(1|1|0) |
- 1: | 3,7-dimethylquercetin 4'-O-methyltransferase [2.1.1.83] | (0|0) |
(0|0|0) |
- 1: | 3-O-acetyl-4'-O-demethylpapaveroxine 4'-O-methyltransferase [2.1.1.352] | (0|0) |
(0|0|0) |
- 1: | 3-aminomethylindole N-methyltransferase [2.1.1.340] | (0|0) |
(0|0|0) |
- 1: | 3-demethylubiquinol 3-O-methyltransferase [2.1.1.64] | (1|0) |
(1|0|0) |
- 1: | 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase [2.1.1.99] | (0|0) |
(0|0|0) |
- 1: | 3-hydroxy-5-methyl-1-naphthoate 3-O-methyltransferase [2.1.1.302] | (0|0) |
(0|0|0) |
- 1: | 3-hydroxyanthranilate 4-C-methyltransferase [2.1.1.97] | (0|0) |
(0|0|0) |
- 1: | 3-methylquercetin 7-O-methyltransferase [2.1.1.82] | (0|0) |
(0|0|0) |
- 1: | 3-phospho-methyltransferase [2.1.1.294] | (0|0) |
(0|0|0) |
- 1: | 4-amino-anhydrotetracycline N(4)-methyltransferase [2.1.1.335] | (0|0) |
(0|0|0) |
- 1: | 4-dimethylallyltryptophan N-methyltransferase [2.1.1.261] | (0|0) |
(0|0|0) |
- 1: | 5'-demethylyatein 5'-O-methyltransferase [2.1.1.330] | (0|0) |
(0|0|0) |
- 1: | 5-hydroxyfuranocoumarin 5-O-methyltransferase [2.1.1.69] | (0|0) |
(0|0|0) |
- 1: | 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase [2.1.1.14] | (1|1) |
(1|1|0) |
- 1: | 5-pentadecatrienyl resorcinol O-methyltransferase [2.1.1.n7] | (0|0) |
(0|0|0) |
- 1: | 6-O-methylnorlaudanosoline 5'-O-methyltransferase [2.1.1.121] | (0|0) |
(0|0|0) |
- 1: | 6-hydroxymellein O-methyltransferase [2.1.1.108] | (0|0) |
(0|0|0) |
- 1: | 6-hydroxytryprostatin B O-methyltransferase [2.1.1.293] | (1|1) |
(1|1|0) |
- 1: | 7-methylxanthosine synthase [2.1.1.158] | (0|0) |
(0|0|0) |
- 1: | 8-amino-8-demethylriboflavin N,N-dimethyltransferase [2.1.1.343] | (0|0) |
(0|0|0) |
- 1: | 8-demethyl-8-alpha-L-rhamnosyl tetracenomycin-C 2'-O-methyltransferase [2.1.1.305] | (0|0) |
(0|0|0) |
- 1: | 8-demethylnovobiocic acid C(8)-methyltransferase [2.1.1.284] | (0|0) |
(0|0|0) |
- 1: | 8-hydroxyfuranocoumarin 8-O-methyltransferase [2.1.1.70] | (0|0) |
(0|0|0) |
- 1: | 8-hydroxyquercetin 8-O-methyltransferase [2.1.1.88] | (0|0) |
(0|0|0) |
- 1: | Acetylserotonin O-methyltransferase [2.1.1.4] | (1|2) |
(1|1|0) |
- 1: | Aklanonic acid methyltransferase [2.1.1.288] | (0|0) |
(0|0|0) |
- 1: | Amine N-methyltransferase [2.1.1.49] | (0|1) |
(0|0|0) |
- 1: | Anaerobilin synthase [2.1.1.342] | (0|0) |
(0|0|0) |
- 1: | Anthranilate N-methyltransferase [2.1.1.111] | (0|0) |
(0|0|0) |
- 1: | Anthranilate O-methyltransferase [2.1.1.277] | (0|1) |
(0|0|0) |
- 1: | Apigenin 4'-O-methyltransferase [2.1.1.75] | (0|0) |
(0|0|0) |
- 1: | Arsenite methyltransferase [2.1.1.137] | (0|0) |
(0|0|0) |
- 1: | Bacteriochlorophyllide d C-12(1)-methyltransferase [2.1.1.331] | (0|0) |
(0|0|0) |
- 1: | Bacteriochlorophyllide d C-20 methyltransferase [2.1.1.333] | (0|0) |
(0|0|0) |
- 1: | Bacteriochlorophyllide d C-8(2)-methyltransferase [2.1.1.332] | (0|0) |
(0|0|0) |
- 1: | Benzoate O-methyltransferase [2.1.1.273] | (0|1) |
(0|0|0) |
- 1: | Betaine--homocysteine S-methyltransferase [2.1.1.5] | (1|1) |
(1|0|0) |
- 1: | Botryococcene C-methyltransferase [2.1.1.263] | (0|0) |
(0|0|0) |
- 1: | Caffeate O-methyltransferase [2.1.1.68] | (1|2) |
(1|1|0) |
- 1: | Caffeine synthase [2.1.1.160] | (0|1) |
(0|0|0) |
- 1: | Caffeoyl-CoA O-methyltransferase [2.1.1.104] | (0|1) |
(0|0|0) |
- 1: | Calmodulin-lysine N-methyltransferase [2.1.1.60] | (0|0) |
(0|0|0) |
- 1: | Carminomycin 4-O-methyltransferase [2.1.1.292] | (0|0) |
(0|0|0) |
- 1: | Carnosine N-methyltransferase [2.1.1.22] | (0|0) |
(0|0|0) |
- 1: | Catechol O-methyltransferase [2.1.1.6] | (0|1) |
(0|0|0) |
- 1: | Chlorophenol O-methyltransferase [2.1.1.136] | (0|0) |
(0|0|0) |
- 1: | Co-methyltransferase [2.1.1.245] | (1|0) |
(1|0|0) |
- 1: | Co-methyltransferase [2.1.1.258] | (0|0) |
(0|0|0) |
- 1: | Cobalt-factor II C(20)-methyltransferase [2.1.1.151] | (0|0) |
(0|0|0) |
- 1: | Cobalt-factor III methyltransferase [2.1.1.272] | (0|0) |
(0|0|0) |
- 1: | Cobalt-precorrin-4 methyltransferase [2.1.1.271] | (1|1) |
(1|0|0) |
- 1: | Cobalt-precorrin-5B (C(1))-methyltransferase [2.1.1.195] | (1|1) |
(1|0|0) |
- 1: | Cobalt-precorrin-6B (C(15))-methyltransferase (decarboxylating) [2.1.1.196] | (0|1) |
(0|0|0) |
- 1: | Cobalt-precorrin-7 (C(5))-methyltransferase [2.1.1.289] | (1|1) |
(1|0|0) |
- 1: | Columbamine O-methyltransferase [2.1.1.118] | (0|0) |
(0|0|0) |
- 1: | Corydaline synthase [2.1.1.147] | (0|0) |
(0|0|0) |
- 1: | Cycloartenol 24-C-methyltransferase [2.1.1.142] | (0|0) |
(0|0|0) |
- 1: | Cyclopropane-fatty-acyl-phospholipid synthase [2.1.1.79] | (0|1) |
(0|0|0) |
- 1: | Cypemycin N-terminal methyltransferase [2.1.1.301] | (0|0) |
(0|0|0) |
- 1: | Cytidylyl-2-hydroxyethylphosphonate methyltransferase [2.1.1.308] | (0|0) |
(0|0|0) |
- 1: | DNA (cytosine-5-)-methyltransferase [2.1.1.37] | (5|3) |
(5|2|0) |
- 1: | Deleted entry [2.1.1.30] | (0|0) |
(0|0|0) |
- 1: | Deleted entry [2.1.1.194] | (0|0) |
(0|0|0) |
- 1: | Deleted entry [2.1.1.138] | (0|0) |
(0|0|0) |
- 1: | Demethyldecarbamoylnovobiocin O-methyltransferase [2.1.1.285] | (0|0) |
(0|0|0) |
- 1: | Demethylluteothin O-methyltransferase [2.1.1.353] | (0|0) |
(0|0|0) |
- 1: | Demethylmacrocin O-methyltransferase [2.1.1.102] | (0|0) |
(0|0|0) |
- 1: | Demethylmenaquinone methyltransferase [2.1.1.163] | (1|1) |
(1|0|0) |
- 1: | Demethylphylloquinol methyltransferase [2.1.1.329] | (0|0) |
(0|0|0) |
- 1: | Demethylrebeccamycin-D-glucose O-methyltransferase [2.1.1.164] | (0|0) |
(0|0|0) |
- 1: | Demethylspheroidene O-methyltransferase [2.1.1.210] | (0|0) |
(0|0|0) |
- 1: | Demethylsterigmatocystin 6-O-methyltransferase [2.1.1.109] | (0|0) |
(0|0|0) |
- 1: | Deoxycytidylate C-methyltransferase [2.1.1.54] | (0|0) |
(0|0|0) |
- 1: | Desmethylxanthohumol 6'-O-methyltransferase [2.1.1.338] | (0|0) |
(0|0|0) |
- 1: | Dimethylglycine N-methyltransferase [2.1.1.161] | (0|0) |
(0|0|0) |
- 1: | Dimethylsulfoniopropionate demethylase [2.1.1.269] | (0|0) |
(0|0|0) |
- 1: | Diphthine methyl ester synthase [2.1.1.314] | (1|1) |
(1|0|0) |
- 1: | Diphthine synthase [2.1.1.98] | (1|1) |
(1|0|0) |
- 1: | Emodin O-methyltransferase [2.1.1.283] | (0|0) |
(0|0|0) |
- 1: | Erythromycin 3''-O-methyltransferase [2.1.1.254] | (0|0) |
(0|0|0) |
- 1: | Fatty-acid O-methyltransferase [2.1.1.15] | (0|0) |
(0|0|0) |
- 1: | Flavone 3'-O-methyltransferase [2.1.1.42] | (1|2) |
(1|1|0) |
- 1: | Flavonoid 3',5'-methyltransferase [2.1.1.267] | (0|0) |
(0|0|0) |
- 1: | Flavonoid 4'-O-methyltransferase [2.1.1.231] | (0|0) |
(0|0|0) |
- 1: | Geranyl diphosphate 2-C-methyltransferase [2.1.1.255] | (0|0) |
(0|0|0) |
- 1: | Gibberellin A(4) carboxyl methyltransferase [2.1.1.276] | (0|0) |
(0|0|0) |
- 1: | Gibberellin A(9) O-methyltransferase [2.1.1.275] | (0|0) |
(0|0|0) |
- 1: | Glucuronoxylan 4-O-methyltransferase [2.1.1.112] | (0|0) |
(0|0|0) |
- 1: | Glycine N-methyltransferase [2.1.1.20] | (0|1) |
(0|0|0) |
- 1: | Glycine/sarcosine N-methyltransferase [2.1.1.156] | (0|1) |
(0|0|0) |
- 1: | Glycine/sarcosine/dimethylglycine N-methyltransferase [2.1.1.162] | (0|0) |
(0|0|0) |
- 1: | Guanidinoacetate N-methyltransferase [2.1.1.2] | (0|1) |
(0|0|0) |
- 1: | Histamine N-methyltransferase [2.1.1.8] | (0|1) |
(0|0|0) |
- 1: | Homocysteine S-methyltransferase [2.1.1.10] | (1|1) |
(1|0|0) |
- 1: | Indole-3-acetate O-methyltransferase [2.1.1.278] | (0|0) |
(0|0|0) |
- 1: | Indolepyruvate C-methyltransferase [2.1.1.47] | (0|0) |
(0|0|0) |
- 1: | Inositol 1-methyltransferase [2.1.1.40] | (0|0) |
(0|0|0) |
- 1: | Inositol 3-methyltransferase [2.1.1.39] | (0|0) |
(0|0|0) |
- 1: | Inositol 4-methyltransferase [2.1.1.129] | (0|0) |
(0|0|0) |
- 1: | Iodophenol O-methyltransferase [2.1.1.26] | (0|0) |
(0|0|0) |
- 1: | Isobutyraldoxime O-methyltransferase [2.1.1.91] | (0|0) |
(0|0|0) |
- 1: | Isoflavone 4'-O-methyltransferase [2.1.1.46] | (1|2) |
(1|1|0) |
- 1: | Isoflavone 7-O-methyltransferase [2.1.1.150] | (1|2) |
(1|1|0) |
- 1: | Isoliquiritigenin 2'-O-methyltransferase [2.1.1.154] | (0|0) |
(0|0|0) |
- 1: | Isoorientin 3'-O-methyltransferase [2.1.1.78] | (0|0) |
(0|0|0) |
- 1: | Jasmonate O-methyltransferase [2.1.1.141] | (0|0) |
(0|0|0) |
- 1: | Juvenile hormone-III synthase [2.1.1.325] | (0|0) |
(0|0|0) |
- 1: | Kaempferol 4'-O-methyltransferase [2.1.1.155] | (0|0) |
(0|0|0) |
- 1: | L-histidine N(alpha)-methyltransferase [2.1.1.44] | (0|0) |
(0|0|0) |
- 1: | L-olivosyl-oleandolide 3-O-methyltransferase [2.1.1.239] | (0|0) |
(0|0|0) |
- 1: | L-tyrosine C(3)-methyltransferase [2.1.1.304] | (0|0) |
(0|0|0) |
- 1: | Licodione 2'-O-methyltransferase [2.1.1.65] | (0|0) |
(0|0|0) |
- 1: | Loganate O-methyltransferase [2.1.1.50] | (0|0) |
(0|0|0) |
- 1: | M methyltransferase [2.1.1.253] | (0|0) |
(0|0|0) |
- 1: | Macrocin O-methyltransferase [2.1.1.101] | (0|0) |
(0|0|0) |
- 1: | Magnesium protoporphyrin IX methyltransferase [2.1.1.11] | (0|0) |
(0|0|0) |
- 1: | Malonyl-[acyl-carrier protein] O-methyltransferase [2.1.1.197] | (2|1) |
(2|1|0) |
- 1: | Menaquinone C(8)-methyltransferase [2.1.1.350] | (0|0) |
(0|0|0) |
- 1: | Methanethiol S-methyltransferase [2.1.1.334] | (0|0) |
(0|0|0) |
- 1: | Methanol--corrinoid protein Co-methyltransferase [2.1.1.90] | (0|0) |
(0|0|0) |
- 1: | Methionine S-methyltransferase [2.1.1.12] | (1|0) |
(1|2|1) |
- 1: | Methionine synthase [2.1.1.13] | (5|5) |
(5|4|3) |
- 1: | Methyl halide transferase [2.1.1.165] | (0|0) |
(0|0|0) |
- 1: | Methylamine--glutamate N-methyltransferase [2.1.1.21] | (0|0) |
(0|0|0) |
- 1: | Methylated-DNA--[protein]-cysteine S-methyltransferase [2.1.1.63] | (2|2) |
(2|1|0) |
- 1: | Methylated-thiol--coenzyme M methyltransferase [2.1.1.251] | (0|0) |
(0|0|0) |
- 1: | Methylene-fatty-acyl-phospholipid synthase [2.1.1.16] | (0|0) |
(0|0|0) |
- 1: | Methylphosphotriester-DNA--[protein]-cysteine S-methyltransferase [2.1.1.n11] | (2|1) |
(2|1|0) |
- 1: | Methylquercetagetin 6-O-methyltransferase [2.1.1.84] | (0|0) |
(0|0|0) |
- 1: | Methyltransferase cap1 [2.1.1.57] | (7|7) |
(7|4|1) |
- 1: | Methyltransferase cap2 [2.1.1.296] | (0|0) |
(0|0|0) |
- 1: | Mitomycin 6-O-methyltransferase [2.1.1.316] | (0|0) |
(0|0|0) |
- 1: | Multisite-specific tRNA:(cytosine-C(5))-methyltransferase [2.1.1.202] | (0|0) |
(0|0|0) |
- 1: | Mycinamicin III 3''-O-methyltransferase [2.1.1.237] | (0|0) |
(0|0|0) |
- 1: | Mycinamicin VI 2''-O-methyltransferase [2.1.1.238] | (0|0) |
(0|0|0) |
- 1: | N,N-dimethyltransferase [2.1.1.234] | (0|0) |
(0|0|0) |
- 1: | N-acetyl-demethylphosphinothricin P-methyltransferase [2.1.1.326] | (0|0) |
(0|0|0) |
- 1: | N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase [2.1.1.105] | (0|0) |
(0|0|0) |
- 1: | N-demethylindolmycin N-methyltransferase [2.1.1.328] | (0|0) |
(0|0|0) |
- 1: | Naringenin 7-O-methyltransferase [2.1.1.232] | (0|0) |
(0|0|0) |
- 1: | Nicotinamide N-methyltransferase [2.1.1.1] | (0|1) |
(0|0|0) |
- 1: | Nicotinate N-methyltransferase [2.1.1.7] | (0|0) |
(0|0|0) |
- 1: | Nocamycin O-methyltransferase [2.1.1.351] | (0|0) |
(0|0|0) |
- 1: | Norbelladine O-methyltransferase [2.1.1.336] | (0|0) |
(0|0|0) |
- 1: | O-demethylpuromycin O-methyltransferase [2.1.1.38] | (0|0) |
(0|0|0) |
- 1: | Ornithine lipid N-methyltransferase [2.1.1.344] | (0|0) |
(0|0|0) |
- 1: | Pavine N-methyltransferase [2.1.1.300] | (0|0) |
(0|0|0) |
- 1: | Peptide chain release factor N(5)-glutamine methyltransferase [2.1.1.297] | (1|1) |
(1|0|0) |
- 1: | Phenazine-1-carboxylate N-methyltransferase [2.1.1.327] | (0|0) |
(0|0|0) |
- 1: | Phenol O-methyltransferase [2.1.1.25] | (0|0) |
(0|0|0) |
- 1: | Phenylethanolamine N-methyltransferase [2.1.1.28] | (0|1) |
(0|0|0) |
- 1: | Phenylpyruvate C(3)-methyltransferase [2.1.1.281] | (0|0) |
(0|0|0) |
- 1: | Phosphatidyl-N-methylethanolamine N-methyltransferase [2.1.1.71] | (0|0) |
(0|0|0) |
- 1: | Phosphatidylethanolamine N-methyltransferase [2.1.1.17] | (0|0) |
(0|0|0) |
- 1: | Phosphoethanolamine N-methyltransferase [2.1.1.103] | (0|0) |
(0|1|0) |
- 1: | Polyprenyldihydroxybenzoate methyltransferase [2.1.1.114] | (0|0) |
(0|0|0) |
- 1: | Polysaccharide O-methyltransferase [2.1.1.18] | (0|0) |
(0|0|0) |
- 1: | Precorrin-2 C(20)-methyltransferase [2.1.1.130] | (1|1) |
(1|0|0) |
- 1: | Precorrin-3B C(17)-methyltransferase [2.1.1.131] | (0|0) |
(0|0|0) |
- 1: | Precorrin-4 C(11)-methyltransferase [2.1.1.133] | (1|1) |
(1|0|0) |
- 1: | Precorrin-6A synthase (deacetylating) [2.1.1.152] | (0|0) |
(0|0|0) |
- 1: | Precorrin-6B C(5,15)-methyltransferase (decarboxylating) [2.1.1.132] | (1|1) |
(1|1|0) |
- 1: | Protein N-terminal methyltransferase [2.1.1.244] | (0|1) |
(0|0|0) |
- 1: | Protein N-terminal monomethyltransferase [2.1.1.299] | (0|1) |
(0|0|0) |
- 1: | Protein-L-isoaspartate(D-aspartate) O-methyltransferase [2.1.1.77] | (1|1) |
(1|0|0) |
- 1: | Protein-S-isoprenylcysteine O-methyltransferase [2.1.1.100] | (0|0) |
(0|0|0) |
- 1: | Protein-glutamate O-methyltransferase [2.1.1.80] | (1|2) |
(1|1|0) |
- 1: | Protein-histidine N-methyltransferase [2.1.1.85] | (2|2) |
(2|1|0) |
- 1: | Psilocybin synthase [2.1.1.345] | (0|0) |
(0|0|0) |
- 1: | Putrescine N-methyltransferase [2.1.1.53] | (0|1) |
(0|0|0) |
- 1: | Pyridine N-methyltransferase [2.1.1.87] | (0|0) |
(0|0|0) |
- 1: | Quercetin 3-O-methyltransferase [2.1.1.76] | (0|0) |
(0|0|0) |
- 1: | Resorcinol O-methyltransferase [2.1.1.n1] | (0|0) |
(0|0|0) |
- 1: | Reticuline N-methyltransferase [2.1.1.337] | (0|0) |
(0|0|0) |
- 1: | Ribosomal protein L3 N(5)-glutamine methyltransferase [2.1.1.298] | (0|1) |
(0|0|0) |
- 1: | Salicylate carboxymethyltransferase [2.1.1.274] | (0|1) |
(0|0|0) |
- 1: | Sarcosine/dimethylglycine N-methyltransferase [2.1.1.157] | (0|1) |
(0|0|0) |
- 1: | Selenocysteine Se-methyltransferase [2.1.1.280] | (0|0) |
(0|0|0) |
- 1: | Site-specific DNA-methyltransferase (adenine-specific) [2.1.1.72] | (1|4) |
(1|0|0) |
- 1: | Site-specific DNA-methyltransferase (cytosine-N(4)-specific) [2.1.1.113] | (0|1) |
(0|1|0) |
- 1: | Small RNA 2'-O-methyltransferase [2.1.1.n8] | (0|0) |
(0|0|0) |
- 1: | Sphingolipid C(9)-methyltransferase [2.1.1.317] | (0|1) |
(0|0|0) |
- 1: | Squalene methyltransferase [2.1.1.262] | (0|0) |
(0|0|0) |
- 1: | Sterigmatocystin 8-O-methyltransferase [2.1.1.110] | (0|0) |
(0|0|0) |
- 1: | Sterol 24-C-methyltransferase [2.1.1.41] | (0|0) |
(0|0|0) |
- 1: | Tabersonine 16-O-methyltransferase [2.1.1.94] | (0|0) |
(0|0|0) |
- 1: | Tellurite methyltransferase [2.1.1.265] | (0|0) |
(0|0|0) |
- 1: | Tetrahydrocolumbamine 2-O-methyltransferase [2.1.1.89] | (0|0) |
(0|0|0) |
- 1: | Tetrahydromethanopterin S-methyltransferase [2.1.1.86] | (1|0) |
(1|0|0) |
- 1: | Tetramethylammonium--corrinoid protein Co-methyltransferase [2.1.1.252] | (0|0) |
(0|0|0) |
- 1: | Theobromine synthase [2.1.1.159] | (0|1) |
(0|0|0) |
- 1: | Thetin--homocysteine S-methyltransferase [2.1.1.3] | (0|0) |
(0|0|0) |
- 1: | Thiocyanate methyltransferase [2.1.1.n4] | (0|0) |
(0|0|0) |
- 1: | Thioether S-methyltransferase [2.1.1.96] | (0|1) |
(0|0|0) |
- 1: | Thiol S-methyltransferase [2.1.1.9] | (0|0) |
(0|0|0) |
- 1: | Thiopurine S-methyltransferase [2.1.1.67] | (1|1) |
(1|0|0) |
- 1: | Thymidylate synthase [2.1.1.45] | (2|2) |
(2|1|0) |
- 1: | Thymidylate synthase (FAD) [2.1.1.148] | (1|1) |
(1|0|0) |
- 1: | Tocopherol C-methyltransferase [2.1.1.95] | (0|0) |
(0|0|0) |
- 1: | Toxoflavin synthase [2.1.1.349] | (0|0) |
(0|0|0) |
- 1: | Trans-aconitate 2-methyltransferase [2.1.1.144] | (1|0) |
(1|0|0) |
- 1: | Trans-aconitate 3-methyltransferase [2.1.1.145] | (0|0) |
(0|0|0) |
- 1: | Trans-anol O-methyltransferase [2.1.1.279] | (0|0) |
(0|0|0) |
- 1: | Trans-resveratrol di-O-methyltransferase [2.1.1.240] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 1.16.1.8 [2.1.1.135] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.129 [2.1.1.134] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.171, 2.1.1.172, 2.1.1.173 and 2.1.1.174 [2.1.1.52] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.181, 2.1.1.182, 2.1.1.183 and 2.1.1.184 [2.1.1.48] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.187 and 2.1.1.188 [2.1.1.51] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.202, 2.1.1.203 and 2.1.1.204 [2.1.1.29] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.211 [2.1.1.n2] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.213, 2.1.1.214, 2.1.1.215 and 2.1.1.216 [2.1.1.32] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.217, 2.1.1.218, 2.1.1.219 and 2.1.1.220 [2.1.1.36] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.221 and 2.1.1.228 [2.1.1.31] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.230 [2.1.1.66] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.244 [2.1.1.n5] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.255 [2.1.1.n6] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.267 [2.1.1.149] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.274 [2.1.1.n9] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.278 [2.1.1.n10] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.280 [2.1.1.n3] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.297 [2.1.1.n16] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.298 [2.1.1.n15] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.300 [2.1.1.n14] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.301 [2.1.1.n13] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.319, 2.1.1.320, 2.1.1.321 and 2.1.1.322 [2.1.1.124] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.319, 2.1.1.320, 2.1.1.321 and 2.1.1.322 [2.1.1.23] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.319, 2.1.1.320, 2.1.1.321 and 2.1.1.322 [2.1.1.125] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.319, 2.1.1.320, 2.1.1.321 and 2.1.1.322 [2.1.1.126] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.329 [2.1.1.n12] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.354 [2.1.1.43] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.37 [2.1.1.73] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.49 [2.1.1.81] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.57 [2.1.1.58] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.69 [2.1.1.92] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.70 [2.1.1.93] | (0|0) |
(0|0|0) |
- 1: | Transferred entry: 2.1.1.77, 2.1.1.80 and 2.1.1.100 [2.1.1.24] | (0|0) |
(0|0|0) |
- 1: | Tricetin 3',4',5'-O-trimethyltransferase [2.1.1.169] | (0|0) |
(0|0|0) |
- 1: | Tricin synthase [2.1.1.175] | (0|0) |
(0|0|0) |
- 1: | Trimethylsulfonium--tetrahydrofolate N-methyltransferase [2.1.1.19] | (0|0) |
(0|0|0) |
- 1: | Tryptophan 2-C-methyltransferase [2.1.1.106] | (0|0) |
(0|0|0) |
- 1: | Type I protein arginine methyltransferase [2.1.1.319] | (1|2) |
(1|1|0) |
- 1: | Type II protein arginine methyltransferase [2.1.1.320] | (1|2) |
(1|1|0) |
- 1: | Type III protein arginine methyltransferase [2.1.1.321] | (0|1) |
(0|1|0) |
- 1: | Type IV protein arginine methyltransferase [2.1.1.322] | (0|0) |
(0|0|0) |
- 1: | Tyramine N-methyltransferase [2.1.1.27] | (0|0) |
(0|0|0) |
- 1: | U6 snRNA m(6)A methyltransferase [2.1.1.346] | (0|1) |
(0|0|0) |
- 1: | Uroporphyrinogen-III C-methyltransferase [2.1.1.107] | (3|3) |
(3|2|1) |
- 1: | Vanillate/3-O-methylgallate O-demethylase [2.1.1.341] | (0|0) |
(0|0|0) |
- 1: | Vitexin 2''-O-rhamnoside 7-O-methyltransferase [2.1.1.153] | (0|0) |
(0|0|0) |
- 1: | Xanthohumol 4-O-methyltransferase [2.1.1.339] | (0|0) |
(0|0|0) |
- 1: | [Cytochrome c]-lysine N-methyltransferase [2.1.1.59] | (1|0) |
(1|0|0) |
- 1: | [Cytochrome c]-methionine S-methyltransferase [2.1.1.123] | (0|0) |
(0|0|0) |
- 1: | [Dimethylamine--corrinoid protein] Co-methyltransferase [2.1.1.249] | (0|0) |
(0|0|0) |
- 1: | [Fructose-bisphosphate aldolase]-lysine N-methyltransferase [2.1.1.259] | (0|0) |
(0|0|0) |
- 1: | [Histone H3]-dimethyl-L-lysine(36) N-methyltransferase [2.1.1.358] | (0|0) |
(0|0|0) |
- 1: | [Histone H3]-lysine(27) N-trimethyltransferase [2.1.1.356] | (0|0) |
(0|0|0) |
- 1: | [Histone H3]-lysine(36) N-dimethyltransferase [2.1.1.357] | (0|0) |
(0|0|0) |
- 1: | [Histone H3]-lysine(36) N-trimethyltransferase [2.1.1.359] | (0|0) |
(0|0|0) |
- 1: | [Histone H3]-lysine(4) N-trimethyltransferase [2.1.1.354] | (4|4) |
(4|1|1) |
- 1: | [Histone H3]-lysine(79) N-trimethyltransferase [2.1.1.360] | (0|0) |
(0|0|0) |
- 1: | [Histone H3]-lysine(9) N-trimethyltransferase [2.1.1.355] | (2|2) |
(2|1|0) |
- 1: | [Histone H4]-N-methyl-L-lysine(20) N-methyltransferase [2.1.1.362] | (0|0) |
(0|0|0) |
- 1: | [Histone H4]-lysine(20) N-methyltransferase [2.1.1.361] | (0|0) |
(0|0|0) |
- 1: | [Methylamine--corrinoid protein] Co-methyltransferase [2.1.1.248] | (1|1) |
(1|0|0) |
- 1: | [Phosphatase 2A protein]-leucine-carboxy methyltransferase [2.1.1.233] | (0|1) |
(0|0|0) |
- 1: | [Ribulose-bisphosphate carboxylase]-lysine N-methyltransferase [2.1.1.127] | (0|0) |
(0|0|0) |
- 1: | [Trehalose-6-phosphate synthase]-L-cysteine S-methyltransferase [2.1.1.318] | (0|0) |
(0|0|0) |
- 1: | [Trimethylamine--corrinoid protein] Co-methyltransferase [2.1.1.250] | (0|0) |
(0|0|0) |
- 1: | dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase [2.1.1.236] | (0|0) |
(0|0|0) |
- 1: | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase [2.1.1.235] | (0|0) |
(0|0|0) |
- 1: | dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase [2.1.1.324] | (0|0) |
(0|0|0) |
- 1: | mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase [2.1.1.62] | (1|1) |
(1|0|0) |
- 1: | mRNA (guanine-N(7)-)-methyltransferase [2.1.1.56] | (9|8) |
(9|5|1) |
- 1: | mRNA m(6)A methyltransferase [2.1.1.348] | (0|1) |
(0|0|0) |
- 1: | methyltransferase [2.1.1.306] | (0|0) |
(0|0|0) |
- 1: | methyltransferase [2.1.1.246] | (0|0) |
(0|0|0) |
- 1: | methyltransferase [2.1.1.247] | (1|1) |
(1|0|0) |
- 1: | methyltransferase [2.1.1.307] | (0|0) |
(0|0|0) |
- 1: | methyltransferase [2.1.1.282] | (1|1) |
(1|0|0) |
- 1: | rRNA small subunit pseudouridine methyltransferase Nep1 [2.1.1.260] | (0|0) |
(0|0|0) |
- 1: | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase [2.1.1.61] | (3|0) |
(3|3|1) |
- 1: | tRNA (adenine(22)-N(1))-methyltransferase [2.1.1.217] | (0|0) |
(0|0|0) |
- 1: | tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase [2.1.1.219] | (0|0) |
(0|0|0) |
- 1: | tRNA (adenine(58)-N(1))-methyltransferase [2.1.1.220] | (0|1) |
(0|0|0) |
- 1: | tRNA (adenine(9)-N(1))-methyltransferase [2.1.1.218] | (0|0) |
(0|0|0) |
- 1: | tRNA (adenine-N(6)-)-methyltransferase [2.1.1.55] | (0|0) |
(0|0|0) |
- 1: | tRNA (carboxymethyluridine(34)-5-O)-methyltransferase [2.1.1.229] | (2|2) |
(2|2|1) |
- 1: | tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase [2.1.1.205] | (0|1) |
(0|0|0) |
- 1: | tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase [2.1.1.200] | (1|0) |
(1|0|0) |
- 1: | tRNA (cytidine(34)-2'-O)-methyltransferase [2.1.1.207] | (1|1) |
(1|0|0) |
- 1: | tRNA (cytidine(56)-2'-O)-methyltransferase [2.1.1.206] | (2|1) |
(2|1|0) |
- 1: | tRNA (cytosine(34)-C(5))-methyltransferase [2.1.1.203] | (0|1) |
(0|0|0) |
- 1: | tRNA (cytosine(38)-C(5))-methyltransferase [2.1.1.204] | (0|1) |
(0|0|0) |
- 1: | tRNA (guanine(10)-N(2))-dimethyltransferase [2.1.1.213] | (1|0) |
(1|1|0) |
- 1: | tRNA (guanine(10)-N(2))-methyltransferase [2.1.1.214] | (0|0) |
(0|0|0) |
- 1: | tRNA (guanine(26)-N(2))-dimethyltransferase [2.1.1.216] | (1|1) |
(1|0|0) |
- 1: | tRNA (guanine(26)-N(2)/guanine(27)-N(2))-dimethyltransferase [2.1.1.215] | (0|0) |
(0|0|0) |
- 1: | tRNA (guanine(37)-N(1))-methyltransferase [2.1.1.228] | (2|2) |
(2|2|0) |
- 1: | tRNA (guanine(46)-N(7))-methyltransferase [2.1.1.33] | (1|1) |
(1|0|0) |
- 1: | tRNA (guanine(6)-N(2))-methyltransferase [2.1.1.256] | (1|0) |
(1|1|0) |
- 1: | tRNA (guanine(9)-N(1))-methyltransferase [2.1.1.221] | (0|0) |
(0|0|0) |
- 1: | tRNA (guanosine(18)-2'-O)-methyltransferase [2.1.1.34] | (1|1) |
(1|0|0) |
- 1: | tRNA (pseudouridine(54)-N(1))-methyltransferase [2.1.1.257] | (1|1) |
(1|0|0) |
- 1: | tRNA (uracil(54)-C(5))-methyltransferase [2.1.1.35] | (1|1) |
(1|0|0) |
- 1: | tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase [2.1.1.223] | (1|1) |
(1|0|0) |
- 1: | tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase [2.1.1.290] | (3|2) |
(3|3|1) |
- 1: | tRNA(Ser) (uridine(44)-2'-O)-methyltransferase [2.1.1.211] | (0|0) |
(0|0|0) |
- 1: | tRNA(Thr) (cytosine(32)-N(3))-methyltransferase [2.1.1.268] | (0|0) |
(0|0|0) |
- 1: | tRNA:m(4)X modification enzyme [2.1.1.225] | (0|0) |
(0|0|0) |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this EC term (Not in SDEC)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
NusB-like | 0 | DIRECT |
Radical SAM enzymes | 0 | DIRECT |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | DIRECT |
L30e-like | 0 | DIRECT |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
Methionine synthase activation domain-like | 0 | DIRECT |
Methionine synthase domain | 0 | DIRECT |
Flavivirus capsid protein C | 0 | DIRECT |
alpha/beta knot | 0 | DIRECT |
Homocysteine S-methyltransferase | 0 | DIRECT |
Monomethylamine methyltransferase MtmB | 0 | DIRECT |
SET domain | 0 | DIRECT |
FAD/NAD(P)-binding domain | 0 | DIRECT |
RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
Tetrapyrrole methylase | 0 | DIRECT |
Thymidylate synthase-complementing protein Thy1 | 0 | DIRECT |
Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
SSo0622-like | 0 | DIRECT |
Siroheme synthase middle domains-like | 0 | DIRECT |
Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
Methylated DNA-protein cysteine methyltransferase domain | 0 | DIRECT |
Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | DIRECT |
UROD/MetE-like | 0 | DIRECT |
Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
CbiD-like | 0 | DIRECT |
RNA-binding domain, RBD | 0.0000000000001395 | DIRECT |
Cobalamin (vitamin B12)-binding domain | 0.000000000002439 | DIRECT |
Dihydropteroate synthetase-like | 0.00000000005932 | DIRECT |
Chromo domain-like | 0.0000000001068 | DIRECT |
FAD-linked reductases, C-terminal domain | 0.00000007286 | DIRECT |
Galactose oxidase, central domain | 0.0000002344 | DIRECT |
HMG-box | 0.0000005933 | DIRECT |
Dihydrofolate reductase-like | 0.000002463 | DIRECT |
E set domains | 0.000008279 | DIRECT |
"Winged helix" DNA-binding domain | 0.00003105 | DIRECT |
Nucleotide-binding domain | 0.00009811 | DIRECT |
Kelch motif | 0.0001121 | DIRECT |
PUA domain-like | 0.0003359 | DIRECT |
CYTH-like phosphatases | 0.001163 | INHERITED FROM: mRNA (guanine-N(7)-)-methyltransferase |
Trypsin-like serine proteases | 0.002608 | INHERITED FROM: mRNA (guanine-N(7)-)-methyltransferase || Methyltransferase cap1 |
Homeodomain-like | 0.009011 | INHERITED FROM: Methylphosphotriester-DNA--[protein]-cysteine S-methyltransferase |
Tudor/PWWP/MBT | 0.01285 | INHERITED FROM: DNA (cytosine-5-)-methyltransferase |
FYVE/PHD zinc finger | 0.01788 | INHERITED FROM: DNA (cytosine-5-)-methyltransferase || [Histone H3]-lysine(4) N-trimethyltransferase |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.08625 | INHERITED FROM: tRNA (guanine(37)-N(1))-methyltransferase |
WW domain | 0.2173 | INHERITED FROM: mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase |
lambda repressor-like DNA-binding domains | 0.7971 | INHERITED FROM: DNA (cytosine-5-)-methyltransferase |
Clavaminate synthase-like | 0.9813 | INHERITED FROM: tRNA (carboxymethyluridine(34)-5-O)-methyltransferase || tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase |
THUMP domain-like | 0.9926 | INHERITED FROM: tRNA (guanine(6)-N(2))-methyltransferase || tRNA (guanine(10)-N(2))-dimethyltransferase |
Nucleic acid-binding proteins | 1 | INHERITED FROM: 23S rRNA (uracil(1939)-C(5))-methyltransferase |
alpha/beta-Hydrolases | 1 | INHERITED FROM: Malonyl-[acyl-carrier protein] O-methyltransferase |
SH3-domain | 1 | INHERITED FROM: Type I protein arginine methyltransferase |
PLP-dependent transferases | 1 | INHERITED FROM: Methionine S-methyltransferase |
TPR-like | 1 | INHERITED FROM: Type II protein arginine methyltransferase |
HD-domain/PDEase-like | 1 | INHERITED FROM: tRNA (cytidine(56)-2'-O)-methyltransferase |
P-loop containing nucleoside triphosphate hydrolases | 1 | INHERITED FROM: mRNA (guanine-N(7)-)-methyltransferase || Methyltransferase cap1 |
DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: mRNA (guanine-N(7)-)-methyltransferase |
NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Uroporphyrinogen-III C-methyltransferase |
DNA/RNA polymerases | 1 | INHERITED FROM: mRNA (guanine-N(7)-)-methyltransferase || Methyltransferase cap1 |
SCOP term | FDR (all) | Annotation (direct or inherited) |
NusB-like | 0 | Direct |
Radical SAM enzymes | 0 | Direct |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | Direct |
L30e-like | 0 | Direct |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
Putative methyltransferase TM0872, insert domain | 0 | Direct |
Methionine synthase activation domain-like | 0 | Direct |
Methionine synthase domain | 0 | Direct |
Flavivirus capsid protein C | 0 | Direct |
alpha/beta knot | 0 | Direct |
Homocysteine S-methyltransferase | 0 | Direct |
Monomethylamine methyltransferase MtmB | 0 | Direct |
SET domain | 0 | Direct |
FAD/NAD(P)-binding domain | 0 | Direct |
RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
Tetrapyrrole methylase | 0 | Direct |
Thymidylate synthase-complementing protein Thy1 | 0 | Direct |
Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
SSo0622-like | 0 | Direct |
Siroheme synthase middle domains-like | 0 | Direct |
Viral glycoprotein, central and dimerisation domains | 0 | Direct |
Methylated DNA-protein cysteine methyltransferase domain | 0 | Direct |
Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | Direct |
UROD/MetE-like | 0 | Direct |
Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
CbiD-like | 0 | Direct |
RNA-binding domain, RBD | 0.0000000000001395 | Direct |
Cobalamin (vitamin B12)-binding domain | 0.000000000002439 | Direct |
Dihydropteroate synthetase-like | 0.00000000005932 | Direct |
Chromo domain-like | 0.0000000001068 | Direct |
FAD-linked reductases, C-terminal domain | 0.00000007286 | Direct |
Galactose oxidase, central domain | 0.0000002344 | Direct |
HMG-box | 0.0000005933 | Direct |
Dihydrofolate reductase-like | 0.000002463 | Direct |
E set domains | 0.000008279 | Direct |
"Winged helix" DNA-binding domain | 0.00003105 | Direct |
Nucleotide-binding domain | 0.00009811 | Direct |
Kelch motif | 0.0001121 | Direct |
PUA domain-like | 0.0003359 | Direct |
CYTH-like phosphatases | 0.001163 | Inherited |
Trypsin-like serine proteases | 0.002608 | Inherited |
Homeodomain-like | 0.009011 | Inherited |
Tudor/PWWP/MBT | 0.01285 | Inherited |
FYVE/PHD zinc finger | 0.01788 | Inherited |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.08625 | Inherited |
WW domain | 0.2173 | Inherited |
lambda repressor-like DNA-binding domains | 0.7971 | Inherited |
Clavaminate synthase-like | 0.9813 | Inherited |
THUMP domain-like | 0.9926 | Inherited |
Nucleic acid-binding proteins | 1 | Inherited |
alpha/beta-Hydrolases | 1 | Inherited |
SH3-domain | 1 | Inherited |
PLP-dependent transferases | 1 | Inherited |
TPR-like | 1 | Inherited |
HD-domain/PDEase-like | 1 | Inherited |
P-loop containing nucleoside triphosphate hydrolases | 1 | Inherited |
DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
DNA/RNA polymerases | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this EC term (SDEC level: Informative)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
Guanidinoacetate methyltransferase | 0 | DIRECT |
hypothetical RNA methyltransferase | 0 | DIRECT |
Chemotaxis receptor methyltransferase CheR, C-terminal domain | 0 | DIRECT |
YhiQ-like | 0 | DIRECT |
mRNA cap (Guanine N-7) methyltransferase | 0 | DIRECT |
AD-003 protein-like | 0 | DIRECT |
Glucose-inhibited division protein B (GidB) | 0 | DIRECT |
N-6 DNA Methylase-like | 0 | DIRECT |
Plant O-methyltransferase, N-terminal domain | 0 | DIRECT |
Viral proteases | 0 | DIRECT |
YhhF-like | 0 | DIRECT |
Plant O-methyltransferase, C-terminal domain | 0 | DIRECT |
TrmB-like | 0 | DIRECT |
TRM1-like | 0 | DIRECT |
Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
RmsB N-terminal domain-like | 0 | DIRECT |
tRNA(1-methyladenosine) methyltransferase-like | 0 | DIRECT |
AF0751-like | 0 | DIRECT |
Glycine N-methyltransferase | 0 | DIRECT |
NOL1/NOP2/sun | 0 | DIRECT |
Salicylic acid carboxyl methyltransferase (SAMT) | 0 | DIRECT |
Histone lysine methyltransferases | 0 | DIRECT |
YbeA-like | 0 | DIRECT |
Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
RNA helicase | 0 | DIRECT |
rRNA adenine dimethylase-like | 0 | DIRECT |
RNA methyltransferase FtsJ | 0 | DIRECT |
Type II DNA methylase | 0 | DIRECT |
Thiopurine S-methyltransferase | 0 | DIRECT |
Thymidylate synthase-complementing protein Thy1 | 0 | DIRECT |
PWWP domain | 0 | DIRECT |
CbiD-like | 0 | DIRECT |
Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
Hypothetical protein MJ0882 | 0 | DIRECT |
Leucine carboxy methyltransferase Ppm1 | 0 | DIRECT |
Protein-L-isoaspartyl O-methyltransferase | 0 | DIRECT |
AF1056-like | 0 | DIRECT |
Monomethylamine methyltransferase MtmB | 0 | DIRECT |
Siroheme synthase middle domains-like | 0 | DIRECT |
Methionine synthase SAM-binding domain | 0 | DIRECT |
Cobalamin-independent methionine synthase | 0 | DIRECT |
Class II viral fusion proteins C-terminal domain | 0 | DIRECT |
Flavivirus capsid protein C | 0 | DIRECT |
Met-10+ protein-like | 0 | DIRECT |
COMT-like | 0 | DIRECT |
N6 adenine-specific DNA methylase, DAM | 0 | DIRECT |
(Uracil-5-)-methyltransferase | 0 | DIRECT |
Histamine methyltransferase | 0 | DIRECT |
Mycolic acid cyclopropane synthase | 0 | DIRECT |
N5-glutamine methyltransferase, HemK | 0 | DIRECT |
Homocysteine S-methyltransferase | 0 | DIRECT |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | DIRECT |
SpoU-like RNA 2'-O ribose methyltransferase | 0 | DIRECT |
Methylated DNA-protein cysteine methyltransferase domain | 0 | DIRECT |
Tetrapyrrole methylase | 0 | DIRECT |
RPA4359-like | 0 | DIRECT |
Precorrin-6Y methyltransferase (CbiT) | 0 | DIRECT |
SSo0622-like | 0 | DIRECT |
Methionine synthase domain | 0 | DIRECT |
Siroheme synthase N-terminal domain-like | 0 | DIRECT |
Methyltransferase 10 domain | 0 | DIRECT |
Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
Hypothetical RNA methyltransferase domain (HRMD) | 0 | DIRECT |
Methyltetrahydrofolate-utiluzing methyltransferases | 0 | DIRECT |
MraW-like putative methyltransferases | 0 | DIRECT |
mRNA cap methylase | 0 | DIRECT |
RNA-dependent RNA-polymerase | 0 | DIRECT |
Arylamine N-methyltransferase | 0 | DIRECT |
YggJ N-terminal domain-like | 0 | DIRECT |
RNA 2'-O ribose methyltransferase substrate binding domain | 0 | DIRECT |
TRAM domain | 0 | DIRECT |
DNA methylase TaqI, N-terminal domain | 0 | DIRECT |
tRNA(m1G37)-methyltransferase TrmD | 0 | DIRECT |
Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | DIRECT |
UbiE/COQ5-like | 0 | DIRECT |
C5 cytosine-specific DNA methylase, DCM | 0 | DIRECT |
YggJ C-terminal domain-like | 0 | DIRECT |
Arginine methyltransferase | 0 | DIRECT |
RuBisCo LSMT catalytic domain | 0 | DIRECT |
Chromo domain | 1.855e-16 | DIRECT |
Cobalamin (vitamin B12)-binding domain | 0.00000000000003275 | DIRECT |
Dihydrofolate reductases | 0.00000001167 | DIRECT |
HMG-box | 0.0000002009 | DIRECT |
Canonical RBD | 0.000000498 | DIRECT |
Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0.000007371 | DIRECT |
AlkB-like | 0.001856 | INHERITED FROM: tRNA (carboxymethyluridine(34)-5-O)-methyltransferase |
PHD domain | 0.03322 | INHERITED FROM: [Histone H3]-lysine(4) N-trimethyltransferase |
WW domain | 0.1178 | INHERITED FROM: mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase |
Biotin biosynthesis protein BioH | 0.5293 | INHERITED FROM: Malonyl-[acyl-carrier protein] O-methyltransferase |
MoCo biosynthesis proteins | 0.5315 | INHERITED FROM: 23S rRNA (adenine(2503)-C(2))-methyltransferase |
SH3-domain | 0.9219 | INHERITED FROM: Type I protein arginine methyltransferase |
Spermidine synthase | 0.9825 | INHERITED FROM: Putrescine N-methyltransferase |
Uroporphyrinogen decarboxylase, UROD | 1 | INHERITED FROM: methyltransferase |
SCOP term | FDR (all) | Annotation (direct or inherited) |
Guanidinoacetate methyltransferase | 0 | Direct |
hypothetical RNA methyltransferase | 0 | Direct |
Chemotaxis receptor methyltransferase CheR, C-terminal domain | 0 | Direct |
YhiQ-like | 0 | Direct |
mRNA cap (Guanine N-7) methyltransferase | 0 | Direct |
AD-003 protein-like | 0 | Direct |
Glucose-inhibited division protein B (GidB) | 0 | Direct |
N-6 DNA Methylase-like | 0 | Direct |
Plant O-methyltransferase, N-terminal domain | 0 | Direct |
Viral proteases | 0 | Direct |
YhhF-like | 0 | Direct |
Plant O-methyltransferase, C-terminal domain | 0 | Direct |
TrmB-like | 0 | Direct |
TRM1-like | 0 | Direct |
Putative methyltransferase TM0872, insert domain | 0 | Direct |
RmsB N-terminal domain-like | 0 | Direct |
tRNA(1-methyladenosine) methyltransferase-like | 0 | Direct |
AF0751-like | 0 | Direct |
Glycine N-methyltransferase | 0 | Direct |
NOL1/NOP2/sun | 0 | Direct |
Salicylic acid carboxyl methyltransferase (SAMT) | 0 | Direct |
Histone lysine methyltransferases | 0 | Direct |
YbeA-like | 0 | Direct |
Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
RNA helicase | 0 | Direct |
rRNA adenine dimethylase-like | 0 | Direct |
RNA methyltransferase FtsJ | 0 | Direct |
Type II DNA methylase | 0 | Direct |
Thiopurine S-methyltransferase | 0 | Direct |
Thymidylate synthase-complementing protein Thy1 | 0 | Direct |
PWWP domain | 0 | Direct |
CbiD-like | 0 | Direct |
Viral glycoprotein, central and dimerisation domains | 0 | Direct |
Hypothetical protein MJ0882 | 0 | Direct |
Leucine carboxy methyltransferase Ppm1 | 0 | Direct |
Protein-L-isoaspartyl O-methyltransferase | 0 | Direct |
AF1056-like | 0 | Direct |
Monomethylamine methyltransferase MtmB | 0 | Direct |
Siroheme synthase middle domains-like | 0 | Direct |
Methionine synthase SAM-binding domain | 0 | Direct |
Cobalamin-independent methionine synthase | 0 | Direct |
Class II viral fusion proteins C-terminal domain | 0 | Direct |
Flavivirus capsid protein C | 0 | Direct |
Met-10+ protein-like | 0 | Direct |
COMT-like | 0 | Direct |
N6 adenine-specific DNA methylase, DAM | 0 | Direct |
(Uracil-5-)-methyltransferase | 0 | Direct |
Histamine methyltransferase | 0 | Direct |
Mycolic acid cyclopropane synthase | 0 | Direct |
N5-glutamine methyltransferase, HemK | 0 | Direct |
Homocysteine S-methyltransferase | 0 | Direct |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | Direct |
SpoU-like RNA 2'-O ribose methyltransferase | 0 | Direct |
Methylated DNA-protein cysteine methyltransferase domain | 0 | Direct |
Tetrapyrrole methylase | 0 | Direct |
RPA4359-like | 0 | Direct |
Precorrin-6Y methyltransferase (CbiT) | 0 | Direct |
SSo0622-like | 0 | Direct |
Methionine synthase domain | 0 | Direct |
Siroheme synthase N-terminal domain-like | 0 | Direct |
Methyltransferase 10 domain | 0 | Direct |
Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
Hypothetical RNA methyltransferase domain (HRMD) | 0 | Direct |
Methyltetrahydrofolate-utiluzing methyltransferases | 0 | Direct |
MraW-like putative methyltransferases | 0 | Direct |
mRNA cap methylase | 0 | Direct |
RNA-dependent RNA-polymerase | 0 | Direct |
Arylamine N-methyltransferase | 0 | Direct |
YggJ N-terminal domain-like | 0 | Direct |
RNA 2'-O ribose methyltransferase substrate binding domain | 0 | Direct |
TRAM domain | 0 | Direct |
DNA methylase TaqI, N-terminal domain | 0 | Direct |
tRNA(m1G37)-methyltransferase TrmD | 0 | Direct |
Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | Direct |
UbiE/COQ5-like | 0 | Direct |
C5 cytosine-specific DNA methylase, DCM | 0 | Direct |
YggJ C-terminal domain-like | 0 | Direct |
Arginine methyltransferase | 0 | Direct |
RuBisCo LSMT catalytic domain | 0 | Direct |
Chromo domain | 1.855e-16 | Direct |
Cobalamin (vitamin B12)-binding domain | 0.00000000000003275 | Direct |
Dihydrofolate reductases | 0.00000001167 | Direct |
HMG-box | 0.0000002009 | Direct |
Canonical RBD | 0.000000498 | Direct |
Hypoxia-inducible factor HIF ihhibitor (FIH1) | 0.000007371 | Direct |
AlkB-like | 0.001856 | Inherited |
PHD domain | 0.03322 | Inherited |
WW domain | 0.1178 | Inherited |
Biotin biosynthesis protein BioH | 0.5293 | Inherited |
MoCo biosynthesis proteins | 0.5315 | Inherited |
SH3-domain | 0.9219 | Inherited |
Spermidine synthase | 0.9825 | Inherited |
Uroporphyrinogen decarboxylase, UROD | 1 | Inherited |
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
 |
Plot tree as:
| |
Download Newick format tree:
|
(show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this EC term (SPEC level: Informative)
Highlighted in gray are those with FDR>0.001
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
L30e-like | 0 | DIRECT |
Flavivirus capsid protein C | 0 | DIRECT |
Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
Tetrapyrrole methylase | 0 | DIRECT |
Methionine synthase activation domain-like | 0 | DIRECT |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | DIRECT |
Siroheme synthase middle domains-like | 0 | DIRECT |
Radical SAM enzymes | 0 | DIRECT |
alpha/beta knot | 0 | DIRECT |
NusB-like | 0 | DIRECT |
Methylated DNA-protein cysteine methyltransferase domain | 0 | DIRECT |
Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
Monomethylamine methyltransferase MtmB | 0 | DIRECT |
SET domain | 0 | DIRECT |
UROD/MetE-like | 0 | DIRECT |
Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | DIRECT |
Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
Methionine synthase domain | 0 | DIRECT |
Homocysteine S-methyltransferase | 0 | DIRECT |
Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
Thymidylate synthase-complementing protein Thy1 | 0 | DIRECT |
RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
SSo0622-like | 0 | DIRECT |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
CbiD-like | 0 | DIRECT |
FAD/NAD(P)-binding domain | 0 | DIRECT |
RNA-binding domain, RBD | 0.00000000000009889 | DIRECT |
Cobalamin (vitamin B12)-binding domain | 0.000000000001756 | DIRECT |
Dihydropteroate synthetase-like | 0.00000000004339 | DIRECT |
Chromo domain-like | 0.00000000007849 | DIRECT |
FAD-linked reductases, C-terminal domain | 0.00000005558 | DIRECT |
Galactose oxidase, central domain | 0.0000001804 | DIRECT |
HMG-box | 0.0000004598 | DIRECT |
Dihydrofolate reductase-like | 0.000001932 | DIRECT |
E set domains | 0.000006532 | DIRECT |
"Winged helix" DNA-binding domain | 0.00002476 | DIRECT |
Nucleotide-binding domain | 0.00007903 | DIRECT |
Kelch motif | 0.00009052 | DIRECT |
PUA domain-like | 0.0002736 | DIRECT |
CYTH-like phosphatases | 0.0009604 | DIRECT |
Trypsin-like serine proteases | 0.002176 | INHERITED FROM: Methyltransferase cap1 || mRNA (guanine-N(7)-)-methyltransferase |
Homeodomain-like | 0.007621 | INHERITED FROM: Methylphosphotriester-DNA--[protein]-cysteine S-methyltransferase |
Tudor/PWWP/MBT | 0.01092 | INHERITED FROM: DNA (cytosine-5-)-methyltransferase |
FYVE/PHD zinc finger | 0.01525 | INHERITED FROM: DNA (cytosine-5-)-methyltransferase || [Histone H3]-lysine(4) N-trimethyltransferase |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.07503 | INHERITED FROM: tRNA (guanine(37)-N(1))-methyltransferase |
WW domain | 0.193 | INHERITED FROM: mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase |
lambda repressor-like DNA-binding domains | 0.7337 | INHERITED FROM: DNA (cytosine-5-)-methyltransferase |
Clavaminate synthase-like | 0.9085 | INHERITED FROM: tRNA (carboxymethyluridine(34)-5-O)-methyltransferase || tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase |
THUMP domain-like | 0.9194 | INHERITED FROM: tRNA (guanine(6)-N(2))-methyltransferase || tRNA (guanine(10)-N(2))-dimethyltransferase |
TPR-like | 0.9283 | INHERITED FROM: Type II protein arginine methyltransferase |
DNA/RNA polymerases | 0.9446 | INHERITED FROM: Methyltransferase cap1 || mRNA (guanine-N(7)-)-methyltransferase |
SH3-domain | 0.9911 | INHERITED FROM: Type I protein arginine methyltransferase |
PLP-dependent transferases | 1 | INHERITED FROM: Methionine S-methyltransferase |
alpha/beta-Hydrolases | 1 | INHERITED FROM: Malonyl-[acyl-carrier protein] O-methyltransferase |
DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: mRNA (guanine-N(7)-)-methyltransferase |
NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Uroporphyrinogen-III C-methyltransferase |
P-loop containing nucleoside triphosphate hydrolases | 1 | INHERITED FROM: Methyltransferase cap1 || mRNA (guanine-N(7)-)-methyltransferase |
HD-domain/PDEase-like | 1 | INHERITED FROM: tRNA (cytidine(56)-2'-O)-methyltransferase |
Nucleic acid-binding proteins | 1 | INHERITED FROM: 23S rRNA (uracil(1939)-C(5))-methyltransferase |
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
L30e-like | 0 | Direct |
Flavivirus capsid protein C | 0 | Direct |
Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
Tetrapyrrole methylase | 0 | Direct |
Methionine synthase activation domain-like | 0 | Direct |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | 0 | Direct |
Siroheme synthase middle domains-like | 0 | Direct |
Radical SAM enzymes | 0 | Direct |
alpha/beta knot | 0 | Direct |
NusB-like | 0 | Direct |
Methylated DNA-protein cysteine methyltransferase domain | 0 | Direct |
Putative methyltransferase TM0872, insert domain | 0 | Direct |
Monomethylamine methyltransferase MtmB | 0 | Direct |
SET domain | 0 | Direct |
UROD/MetE-like | 0 | Direct |
Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0 | Direct |
Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
Methionine synthase domain | 0 | Direct |
Homocysteine S-methyltransferase | 0 | Direct |
Viral glycoprotein, central and dimerisation domains | 0 | Direct |
Thymidylate synthase-complementing protein Thy1 | 0 | Direct |
RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
SSo0622-like | 0 | Direct |
S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
CbiD-like | 0 | Direct |
FAD/NAD(P)-binding domain | 0 | Direct |
RNA-binding domain, RBD | 0.00000000000009889 | Direct |
Cobalamin (vitamin B12)-binding domain | 0.000000000001756 | Direct |
Dihydropteroate synthetase-like | 0.00000000004339 | Direct |
Chromo domain-like | 0.00000000007849 | Direct |
FAD-linked reductases, C-terminal domain | 0.00000005558 | Direct |
Galactose oxidase, central domain | 0.0000001804 | Direct |
HMG-box | 0.0000004598 | Direct |
Dihydrofolate reductase-like | 0.000001932 | Direct |
E set domains | 0.000006532 | Direct |
"Winged helix" DNA-binding domain | 0.00002476 | Direct |
Nucleotide-binding domain | 0.00007903 | Direct |
Kelch motif | 0.00009052 | Direct |
PUA domain-like | 0.0002736 | Direct |
CYTH-like phosphatases | 0.0009604 | Direct |
Trypsin-like serine proteases | 0.002176 | Inherited |
Homeodomain-like | 0.007621 | Inherited |
Tudor/PWWP/MBT | 0.01092 | Inherited |
FYVE/PHD zinc finger | 0.01525 | Inherited |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.07503 | Inherited |
WW domain | 0.193 | Inherited |
lambda repressor-like DNA-binding domains | 0.7337 | Inherited |
Clavaminate synthase-like | 0.9085 | Inherited |
THUMP domain-like | 0.9194 | Inherited |
TPR-like | 0.9283 | Inherited |
DNA/RNA polymerases | 0.9446 | Inherited |
SH3-domain | 0.9911 | Inherited |
PLP-dependent transferases | 1 | Inherited |
alpha/beta-Hydrolases | 1 | Inherited |
DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
P-loop containing nucleoside triphosphate hydrolases | 1 | Inherited |
HD-domain/PDEase-like | 1 | Inherited |
Nucleic acid-binding proteins | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (SPEC level: Informative)
Highlighted in gray are those with FDR>0.001
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
55315,75217 55315 - L30e-like 75217 - alpha/beta knot | 0 | DIRECT |
82282,51717 82282 - Homocysteine S-methyltransferase 51717 - Dihydropteroate synthetase-like | 0 | DIRECT |
50494,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53155,46767 53155 - Methylated DNA-protein cysteine methyltransferase domain 46767 - Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | DIRECT |
82199,81822 82199 - SET domain 81822 - RuBisCo LSMT C-terminal, substrate-binding domain | 0 | DIRECT |
57884,46689 57884 - Ada DNA repair protein, N-terminal domain (N-Ada 10) 46689 - Homeodomain-like | 0 | DIRECT |
51726,51726 51726 - UROD/MetE-like 51726 - UROD/MetE-like | 0 | DIRECT |
56983,81296 56983 - Viral glycoprotein, central and dimerisation domains 81296 - E set domains | 0 | DIRECT |
53790,53335 53790 - Tetrapyrrole methylase 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
88697,75217 88697 - PUA domain-like 75217 - alpha/beta knot | 0 | DIRECT |
53335,53335 53335 - S-adenosyl-L-methionine-dependent methyltransferases 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
54160,82199 54160 - Chromo domain-like 82199 - SET domain | 0 | DIRECT |
51197,53335 51197 - Clavaminate synthase-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
54160,53335 54160 - Chromo domain-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
88697,53335 88697 - PUA domain-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
51735,75615 51735 - NAD(P)-binding Rossmann-fold domains 75615 - Siroheme synthase middle domains-like | 0 | DIRECT |
50044,53335 50044 - SH3-domain 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
48013,53335 48013 - NusB-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
75217,54593 75217 - alpha/beta knot 54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | DIRECT |
53335,53383 53335 - S-adenosyl-L-methionine-dependent methyltransferases 53383 - PLP-dependent transferases | 0 | DIRECT |
75217,109604 75217 - alpha/beta knot 109604 - HD-domain/PDEase-like | 0 | DIRECT |
143437,53335 143437 - THUMP domain-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
53335,50249 53335 - S-adenosyl-L-methionine-dependent methyltransferases 50249 - Nucleic acid-binding proteins | 0 | DIRECT |
53335,56672 53335 - S-adenosyl-L-methionine-dependent methyltransferases 56672 - DNA/RNA polymerases | 0 | DIRECT |
47413,53335 47413 - lambda repressor-like DNA-binding domains 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
51717,47644 51717 - Dihydropteroate synthetase-like 47644 - Methionine synthase domain | 0 | DIRECT |
48452,53335 48452 - TPR-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
50249,53335 50249 - Nucleic acid-binding proteins 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
55154,56091 55154 - CYTH-like phosphatases 56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
75217,75217 75217 - alpha/beta knot 75217 - alpha/beta knot | 0 | DIRECT |
75615,53790 75615 - Siroheme synthase middle domains-like 53790 - Tetrapyrrole methylase | 0 | DIRECT |
47757,53335 47757 - Chemotaxis receptor methyltransferase CheR, N-terminal domain 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
47644,52242 47644 - Methionine synthase domain 52242 - Cobalamin (vitamin B12)-binding domain | 0 | DIRECT |
46785,53335 46785 - "Winged helix" DNA-binding domain 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
52242,56507 52242 - Cobalamin (vitamin B12)-binding domain 56507 - Methionine synthase activation domain-like | 0 | DIRECT |
53335,50965 53335 - S-adenosyl-L-methionine-dependent methyltransferases 50965 - Galactose oxidase, central domain | 0 | DIRECT |
50965,51197 50965 - Galactose oxidase, central domain 51197 - Clavaminate synthase-like | 0 | DIRECT |
53597,55831 53597 - Dihydrofolate reductase-like 55831 - Thymidylate synthase/dCMP hydroxymethylase | 0 | DIRECT |
54928,51197 54928 - RNA-binding domain, RBD 51197 - Clavaminate synthase-like | 0 | DIRECT |
117281,51197 117281 - Kelch motif 51197 - Clavaminate synthase-like | 0 | DIRECT |
53335,51905 53335 - S-adenosyl-L-methionine-dependent methyltransferases 51905 - FAD/NAD(P)-binding domain | 0 | DIRECT |
53335,81799 53335 - S-adenosyl-L-methionine-dependent methyltransferases 81799 - Putative methyltransferase TM0872, insert domain | 0 | DIRECT |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0.0000000006318 | DIRECT |
53474,53335 53474 - alpha/beta-Hydrolases 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.00000002415 | DIRECT |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0.0000001825 | DIRECT |
51971,54373 51971 - Nucleotide-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0.03216 | INHERITED FROM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.8609 | INHERITED FROM: Methyltransferase cap1 || mRNA (guanine-N(7)-)-methyltransferase |
53383,53383 53383 - PLP-dependent transferases 53383 - PLP-dependent transferases | 1 | INHERITED FROM: Methionine S-methyltransferase |
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
55315,75217 55315 - L30e-like 75217 - alpha/beta knot | 0 | Direct |
82282,51717 82282 - Homocysteine S-methyltransferase 51717 - Dihydropteroate synthetase-like | 0 | Direct |
50494,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53155,46767 53155 - Methylated DNA-protein cysteine methyltransferase domain 46767 - Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 0 | Direct |
82199,81822 82199 - SET domain 81822 - RuBisCo LSMT C-terminal, substrate-binding domain | 0 | Direct |
57884,46689 57884 - Ada DNA repair protein, N-terminal domain (N-Ada 10) 46689 - Homeodomain-like | 0 | Direct |
51726,51726 51726 - UROD/MetE-like 51726 - UROD/MetE-like | 0 | Direct |
56983,81296 56983 - Viral glycoprotein, central and dimerisation domains 81296 - E set domains | 0 | Direct |
53790,53335 53790 - Tetrapyrrole methylase 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
88697,75217 88697 - PUA domain-like 75217 - alpha/beta knot | 0 | Direct |
53335,53335 53335 - S-adenosyl-L-methionine-dependent methyltransferases 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
54160,82199 54160 - Chromo domain-like 82199 - SET domain | 0 | Direct |
51197,53335 51197 - Clavaminate synthase-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
54160,53335 54160 - Chromo domain-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
88697,53335 88697 - PUA domain-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
51735,75615 51735 - NAD(P)-binding Rossmann-fold domains 75615 - Siroheme synthase middle domains-like | 0 | Direct |
50044,53335 50044 - SH3-domain 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
48013,53335 48013 - NusB-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
75217,54593 75217 - alpha/beta knot 54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0 | Direct |
53335,53383 53335 - S-adenosyl-L-methionine-dependent methyltransferases 53383 - PLP-dependent transferases | 0 | Direct |
75217,109604 75217 - alpha/beta knot 109604 - HD-domain/PDEase-like | 0 | Direct |
143437,53335 143437 - THUMP domain-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
53335,50249 53335 - S-adenosyl-L-methionine-dependent methyltransferases 50249 - Nucleic acid-binding proteins | 0 | Direct |
53335,56672 53335 - S-adenosyl-L-methionine-dependent methyltransferases 56672 - DNA/RNA polymerases | 0 | Direct |
47413,53335 47413 - lambda repressor-like DNA-binding domains 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
51717,47644 51717 - Dihydropteroate synthetase-like 47644 - Methionine synthase domain | 0 | Direct |
48452,53335 48452 - TPR-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
50249,53335 50249 - Nucleic acid-binding proteins 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
55154,56091 55154 - CYTH-like phosphatases 56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
75217,75217 75217 - alpha/beta knot 75217 - alpha/beta knot | 0 | Direct |
75615,53790 75615 - Siroheme synthase middle domains-like 53790 - Tetrapyrrole methylase | 0 | Direct |
47757,53335 47757 - Chemotaxis receptor methyltransferase CheR, N-terminal domain 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
47644,52242 47644 - Methionine synthase domain 52242 - Cobalamin (vitamin B12)-binding domain | 0 | Direct |
46785,53335 46785 - "Winged helix" DNA-binding domain 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
52242,56507 52242 - Cobalamin (vitamin B12)-binding domain 56507 - Methionine synthase activation domain-like | 0 | Direct |
53335,50965 53335 - S-adenosyl-L-methionine-dependent methyltransferases 50965 - Galactose oxidase, central domain | 0 | Direct |
50965,51197 50965 - Galactose oxidase, central domain 51197 - Clavaminate synthase-like | 0 | Direct |
53597,55831 53597 - Dihydrofolate reductase-like 55831 - Thymidylate synthase/dCMP hydroxymethylase | 0 | Direct |
54928,51197 54928 - RNA-binding domain, RBD 51197 - Clavaminate synthase-like | 0 | Direct |
117281,51197 117281 - Kelch motif 51197 - Clavaminate synthase-like | 0 | Direct |
53335,51905 53335 - S-adenosyl-L-methionine-dependent methyltransferases 51905 - FAD/NAD(P)-binding domain | 0 | Direct |
53335,81799 53335 - S-adenosyl-L-methionine-dependent methyltransferases 81799 - Putative methyltransferase TM0872, insert domain | 0 | Direct |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0.0000000006318 | Direct |
53474,53335 53474 - alpha/beta-Hydrolases 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.00000002415 | Direct |
51905,54373 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0.0000001825 | Direct |
51971,54373 51971 - Nucleotide-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0.03216 | Inherited |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.8609 | Inherited |
53383,53383 53383 - PLP-dependent transferases 53383 - PLP-dependent transferases | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (SPEC level: Informative)
Highlighted in gray are those with FDR>0.001
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50494,52540,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53335,50965,51197 53335 - S-adenosyl-L-methionine-dependent methyltransferases 50965 - Galactose oxidase, central domain 51197 - Clavaminate synthase-like | 0 | DIRECT |
54928,51197,53335 54928 - RNA-binding domain, RBD 51197 - Clavaminate synthase-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
82282,51717,47644 82282 - Homocysteine S-methyltransferase 51717 - Dihydropteroate synthetase-like 47644 - Methionine synthase domain | 0 | DIRECT |
51717,47644,52242 51717 - Dihydropteroate synthetase-like 47644 - Methionine synthase domain 52242 - Cobalamin (vitamin B12)-binding domain | 0 | DIRECT |
57903,57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | DIRECT |
47644,52242,56507 47644 - Methionine synthase domain 52242 - Cobalamin (vitamin B12)-binding domain 56507 - Methionine synthase activation domain-like | 0 | DIRECT |
53335,51905,54373 53335 - S-adenosyl-L-methionine-dependent methyltransferases 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | DIRECT |
51735,75615,53790 51735 - NAD(P)-binding Rossmann-fold domains 75615 - Siroheme synthase middle domains-like 53790 - Tetrapyrrole methylase | 0 | DIRECT |
53335,53383,53383 53335 - S-adenosyl-L-methionine-dependent methyltransferases 53383 - PLP-dependent transferases 53383 - PLP-dependent transferases | 0 | DIRECT |
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50494,52540,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53335,50965,51197 53335 - S-adenosyl-L-methionine-dependent methyltransferases 50965 - Galactose oxidase, central domain 51197 - Clavaminate synthase-like | 0 | Direct |
54928,51197,53335 54928 - RNA-binding domain, RBD 51197 - Clavaminate synthase-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
82282,51717,47644 82282 - Homocysteine S-methyltransferase 51717 - Dihydropteroate synthetase-like 47644 - Methionine synthase domain | 0 | Direct |
51717,47644,52242 51717 - Dihydropteroate synthetase-like 47644 - Methionine synthase domain 52242 - Cobalamin (vitamin B12)-binding domain | 0 | Direct |
57903,57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | Direct |
47644,52242,56507 47644 - Methionine synthase domain 52242 - Cobalamin (vitamin B12)-binding domain 56507 - Methionine synthase activation domain-like | 0 | Direct |
53335,51905,54373 53335 - S-adenosyl-L-methionine-dependent methyltransferases 51905 - FAD/NAD(P)-binding domain 54373 - FAD-linked reductases, C-terminal domain | 0 | Direct |
51735,75615,53790 51735 - NAD(P)-binding Rossmann-fold domains 75615 - Siroheme synthase middle domains-like 53790 - Tetrapyrrole methylase | 0 | Direct |
53335,53383,53383 53335 - S-adenosyl-L-methionine-dependent methyltransferases 53383 - PLP-dependent transferases 53383 - PLP-dependent transferases | 0 | Direct |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
 |
Plot tree as:
| |
Download Newick format tree:
|
(show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|