Enzyme Commission (EC): Fatty-acid synthase system

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children)	EC term [EC ID] <#Children>	(#SF|#FA)	#Supra-domain (Single|Duplex|Triple)
+ + + + 4:	root [root] <7>
+ + + 3:	Transferases [2] <10>	(445|680)	(444|535|275)
+ + 2:	Acyltransferases [2.3] <3>	(128|157)	(128|116|43)
+ 1:	Transferring groups other than amino-acyl groups [2.3.1] <303>	(68|81)	(68|45|17)
0:	Fatty-acid synthase system [2.3.1.85]	(8|8)	(8|5|3)

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Superfamily

Superfamily domains annotated to this EC term (SDEC level: Highly Informative)
Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
GroES-like	0.0000000000003876	DIRECT
ACP-like	0.0000000000005052	DIRECT
FabD/lysophospholipase-like	0.00000000007513	DIRECT
Probable ACP-binding domain of malonyl-CoA ACP transacylase	0.0000000007769	DIRECT
S-adenosyl-L-methionine-dependent methyltransferases	0.0000007666	DIRECT
alpha/beta-Hydrolases	0.000002665	DIRECT
NAD(P)-binding Rossmann-fold domains	0.000005643	DIRECT
Thiolase-like	0.0002955	DIRECT

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Family

Family domains annotated to this EC term (Not in SDEC)
Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
Acyl-carrier protein (ACP)	0	DIRECT
Thioesterase domain of polypeptide, polyketide and fatty acid synthases	3.693e-16	DIRECT
Alcohol dehydrogenase-like, C-terminal domain	0.0000000000001558	DIRECT
Alcohol dehydrogenase-like, N-terminal domain	0.0000000000002099	DIRECT
Tyrosine-dependent oxidoreductases	0.00000000002274	DIRECT
FabD-like	0.000000003329	DIRECT
Probable ACP-binding domain of malonyl-CoA ACP transacylase	0.0000000206	DIRECT
Thiolase-related	0.0000005824	DIRECT

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Supra-domain (including individual superfamily)

Supra-domains annotated to this EC term (SPEC level: Highly Informative)
Highlighted in gray are those with FDR>0.001

Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
GroES-like	0.0000000000002767	DIRECT
ACP-like	0.000000000000361	DIRECT
FabD/lysophospholipase-like	0.00000000005505	DIRECT
Probable ACP-binding domain of malonyl-CoA ACP transacylase	0.0000000005773	DIRECT
S-adenosyl-L-methionine-dependent methyltransferases	0.0000005963	DIRECT
alpha/beta-Hydrolases	0.000002089	DIRECT
NAD(P)-binding Rossmann-fold domains	0.000004439	DIRECT
Thiolase-like	0.0002405	DIRECT

Supra-domains annotated to this EC term (SPEC level: Highly Informative)
Highlighted in gray are those with FDR>0.001

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
47336,53474 47336 - ACP-like 53474 - alpha/beta-Hydrolases	7.073e-16	DIRECT
50129,51735 50129 - GroES-like 51735 - NAD(P)-binding Rossmann-fold domains	0.0000000000002673	DIRECT
51735,51735 51735 - NAD(P)-binding Rossmann-fold domains 51735 - NAD(P)-binding Rossmann-fold domains	0.00000000001109	DIRECT
51735,47336 51735 - NAD(P)-binding Rossmann-fold domains 47336 - ACP-like	0.00000000001598	DIRECT
52151,55048 52151 - FabD/lysophospholipase-like 55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase	0.0000000005773	DIRECT

Supra-domains annotated to this EC term (SPEC level: Highly Informative)
Highlighted in gray are those with FDR>0.001

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
51735,47336,53474 51735 - NAD(P)-binding Rossmann-fold domains 47336 - ACP-like 53474 - alpha/beta-Hydrolases	0	DIRECT
50129,51735,51735 50129 - GroES-like 51735 - NAD(P)-binding Rossmann-fold domains 51735 - NAD(P)-binding Rossmann-fold domains	0.0000000000001077	DIRECT
51735,51735,47336 51735 - NAD(P)-binding Rossmann-fold domains 51735 - NAD(P)-binding Rossmann-fold domains 47336 - ACP-like	0.000000000009157	DIRECT