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Enzyme Commission (EC): Transferring phosphorus-containing groups
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: EC Hierarchy (from IntEnz release 70)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this EC term (SDEC level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Phosphohistidine domain | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| HPr-like | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Retrovirus capsid dimerization domain-like | 0 | DIRECT |
| Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
| EF-hand | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| YrdC/RibB | 0 | DIRECT |
| ApbE-like | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| L domain-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
| DNA polymerase III chi subunit | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| HAMP domain-like | 0 | DIRECT |
| CheW-like | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| PPK N-terminal domain-like | 0 | DIRECT |
| Riboflavin kinase-like | 0 | DIRECT |
| TAF(II)230 TBP-binding fragment | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Retroviral matrix proteins | 0 | DIRECT |
| DAK1/DegV-like | 0 | DIRECT |
| PK C-terminal domain-like | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| alpha-D-mannose-specific plant lectins | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| Glycerate kinase I | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| Ribonuclease H-like | 0 | DIRECT |
| Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
| BAR/IMD domain-like | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| YgbK-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| RNI-like | 0 | DIRECT |
| PTS system fructose IIA component-like | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| Sporulation response regulatory protein Spo0B | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| Trypsin-like serine proteases | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| RNA polymerase subunit RPB10 | 0 | DIRECT |
| RPB5-like RNA polymerase subunit | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| PsbU/PolX domain-like | 0 | DIRECT |
| PTS IIb component | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Fic-like | 0 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
| PHP domain-like | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| Immunoglobulin | 0 | DIRECT |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | DIRECT |
| Insert subdomain of RNA polymerase alpha subunit | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| PHP14-like | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Glucose permease domain IIB | 0 | DIRECT |
| Phosphoglycerate kinase | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| CheY-binding domain of CheA | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| Trm112p-like | 0 | DIRECT |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
| Thiamin pyrophosphokinase, catalytic domain | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| PTS system IIB component-like | 0 | DIRECT |
| AF1531-like | 0 | DIRECT |
| Poly(A) polymerase catalytic subunit-like | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| Sensory domain-like | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| CofD-like | 0 | DIRECT |
| FAT domain of focal adhesion kinase | 0 | DIRECT |
| GAF domain-like | 0 | DIRECT |
| YojJ-like | 0 | DIRECT |
| Protein kinase-like (PK-like) | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| SAM/Pointed domain | 0 | DIRECT |
| C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| Carbamate kinase-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| RPB6/omega subunit-like | 0 | DIRECT |
| Poly A polymerase C-terminal region-like | 0 | DIRECT |
| DhaL-like | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0.00000000000001193 | DIRECT |
| CheY-like | 0.000000000001922 | DIRECT |
| ARM repeat | 0.000000000006522 | DIRECT |
| Replicase NSP9 | 0.00000000001027 | DIRECT |
| Coronavirus NSP10-like | 0.00000000001027 | DIRECT |
| Coronavirus NSP8-like | 0.00000000001027 | DIRECT |
| Coronavirus NSP7-like | 0.00000000001027 | DIRECT |
| Ubiquitin-like | 0.0000000001648 | DIRECT |
| RNA polymerase subunits | 0.0000000001848 | DIRECT |
| Duplicated hybrid motif | 0.0000000003566 | DIRECT |
| GckA/TtuD-like | 0.000000002487 | DIRECT |
| HD-domain/PDEase-like | 0.000000008509 | DIRECT |
| NSP3A-like | 0.0000000541 | DIRECT |
| PX domain | 0.00000005433 | DIRECT |
| Hedgehog/intein (Hint) domain | 0.0000006691 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0.000004199 | DIRECT |
| GroEL apical domain-like | 0.000006709 | DIRECT |
| Second domain of FERM | 0.00001163 | DIRECT |
| CRAL/TRIO domain | 0.00001322 | DIRECT |
| YWTD domain | 0.00001811 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0.00003643 | DIRECT |
| Glutamine synthetase/guanido kinase | 0.00006841 | DIRECT |
| DEATH domain | 0.0001123 | DIRECT |
| IpsF-like | 0.0001406 | DIRECT |
| NTF2-like | 0.0001777 | DIRECT |
| Homing endonucleases | 0.0002917 | DIRECT |
| MIT domain | 0.0006833 | DIRECT |
| SARS Nsp1-like | 0.003921 | INHERITED FROM: Nucleotidyltransferases || RNA-directed RNA polymerase |
| Myosin rod fragments | 0.005558 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| HIT-like | 0.006852 | INHERITED FROM: ATP adenylyltransferase || Nucleotidyltransferases || Sulfate adenylyltransferase (ADP) || UDP-glucose--hexose-1-phosphate uridylyltransferase |
| GTPase activation domain, GAP | 0.007601 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Chaperone J-domain | 0.007985 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| TPR-like | 0.009254 | INHERITED FROM: Dual-specificity kinases (those acting on Ser/Thr and Tyr residues) || Dual-specificity kinase || Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || Protein adenylyltransferase |
| Molybdenum cofactor biosynthesis proteins | 0.01066 | INHERITED FROM: Nucleotidyltransferases || FAD synthase || Molybdopterin adenylyltransferase |
| PDZ domain-like | 0.01085 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Nucleic acid-binding proteins | 0.01358 | INHERITED FROM: Nucleotidyltransferases || mRNA guanylyltransferase || Polyribonucleotide nucleotidyltransferase |
| C-terminal domain of transcriptional repressors | 0.02807 | INHERITED FROM: Pantothenate kinase || Phosphotransferases with an alcohol group as acceptor |
| Rubredoxin-like | 0.03057 | INHERITED FROM: Adenylate kinase || Phosphotransferases with a phosphate group as acceptor |
| GroEL-intermediate domain like | 0.04421 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || 1-phosphatidylinositol-3-phosphate 5-kinase |
| HCP-like | 0.04428 | INHERITED FROM: [Elongation factor 2] kinase || Protein-serine/threonine kinases |
| cAMP-binding domain-like | 0.05607 | INHERITED FROM: Protein-serine/threonine kinases || cGMP-dependent protein kinase |
| RCC1/BLIP-II | 0.0618 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| C-type lectin-like | 0.06839 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| CYTH-like phosphatases | 0.1029 | INHERITED FROM: mRNA guanylyltransferase |
| Nucleotide cyclase | 0.1069 | INHERITED FROM: Nucleotidyltransferases || Diguanylate cyclase |
| SMAD/FHA domain | 0.131 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| SCOP hierarchy in SUPERFAMILY | 0.1877 | INHERITED FROM: cAMP-dependent protein kinase || Protein-serine/threonine kinases |
| WD40 repeat-like | 0.2833 | INHERITED FROM: [Myosin heavy-chain] kinase || Protein-serine/threonine kinases |
| Macro domain-like | 0.3529 | INHERITED FROM: Nucleotidyltransferases || Polynucleotide adenylyltransferase || RNA-directed RNA polymerase |
| SAICAR synthase-like | 0.5358 | INHERITED FROM: Inositol-trisphosphate 3-kinase || Phosphotransferases with an alcohol group as acceptor || 1-phosphatidylinositol-5-phosphate 4-kinase || Inositol-tetrakisphosphate 5-kinase || Inositol-polyphosphate multikinase || Inositol-hexakisphosphate kinase || 1-phosphatidylinositol-4-phosphate 5-kinase || 1-phosphatidylinositol-3-phosphate 5-kinase || Phosphatidylinositol-4,5-bisphosphate 3-kinase |
| Cyclin-like | 0.6034 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Homeodomain-like | 0.7071 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || Glucokinase |
| MoeA N-terminal region -like | 0.7521 | INHERITED FROM: Nucleotidyltransferases || Molybdopterin adenylyltransferase |
| MoeA C-terminal domain-like | 0.7521 | INHERITED FROM: Nucleotidyltransferases || Molybdopterin adenylyltransferase |
| Zinc beta-ribbon | 0.769 | INHERITED FROM: DNA-directed RNA polymerase |
| UBA-like | 0.7762 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| PurM N-terminal domain-like | 0.7838 | INHERITED FROM: Thiamine-phosphate kinase || Phosphotransferases with paired acceptors || Selenide, water dikinase |
| Globin-like | 0.7873 | INHERITED FROM: Diguanylate cyclase |
| PurM C-terminal domain-like | 0.7897 | INHERITED FROM: Thiamine-phosphate kinase || Phosphotransferases with paired acceptors || Selenide, water dikinase |
| Galactose oxidase, central domain | 0.8163 | INHERITED FROM: Guanylate kinase || Phosphotransferases with a phosphate group as acceptor |
| Ribonuclease Rh-like | 0.881 | INHERITED FROM: RNA-directed RNA polymerase |
| Kringle-like | 0.9785 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases |
| EPT/RTPC-like | 1 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || Shikimate kinase |
| Cysteine proteinases | 1 | INHERITED FROM: RNA-directed RNA polymerase |
| "Winged helix" DNA-binding domain | 1 | INHERITED FROM: CTP-dependent riboflavin kinase || 1-phosphatidylinositol-3-phosphate 5-kinase |
| Thioredoxin-like | 1 | INHERITED FROM: Protein-histidine kinases |
| (Phosphotyrosine protein) phosphatases II | 1 | INHERITED FROM: mRNA guanylyltransferase |
| DNase I-like | 1 | INHERITED FROM: RNA-directed DNA polymerase |
| ALDH-like | 1 | INHERITED FROM: Glutamate 5-kinase |
| Concanavalin A-like lectins/glucanases | 1 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| RuvA domain 2-like | 1 | INHERITED FROM: Diadenylate cyclase |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
| Dihydropteroate synthetase-like | 1 | INHERITED FROM: Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | INHERITED FROM: mRNA guanylyltransferase || RNA-directed RNA polymerase |
| Nudix | 1 | INHERITED FROM: ADP-D-ribose pyrophosphorylase |
| FYVE/PHD zinc finger | 1 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase || 1-phosphatidylinositol-3-phosphate 5-kinase |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase || Transferases for other substituted phosphate groups |
| Heme oxygenase-like | 1 | INHERITED FROM: Hydroxymethylpyrimidine kinase || Phosphooxymethylpyrimidine kinase |
| RNA-binding domain, RBD | 1 | INHERITED FROM: Polynucleotide adenylyltransferase || RNA uridylyltransferase |
| Phosphoenolpyruvate/pyruvate domain | 1 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || Pyruvate, phosphate dikinase || Phosphotransferases with paired acceptors || Pyruvate kinase || Protein-N(pi)-phosphohistidine--D-fructose phosphotransferase || Phosphoenolpyruvate--protein phosphotransferase || Phosphotransferases with a nitrogenous group as acceptor || Pyruvate, water dikinase |
| HAD-like | 1 | INHERITED FROM: Polynucleotide 5'-hydroxyl-kinase || N-acylneuraminate cytidylyltransferase |
| Clavaminate synthase-like | 1 | INHERITED FROM: RNA-directed RNA polymerase |
| Bromodomain | 1 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase || Non-specific serine/threonine protein kinase |
| Adenine nucleotide alpha hydrolases-like | 1 | INHERITED FROM: Sulfate adenylyltransferase || FAD synthase |
| lambda repressor-like DNA-binding domains | 1 | INHERITED FROM: Nicotinamide-nucleotide adenylyltransferase || Ribosylnicotinamide kinase |
| Ankyrin repeat | 1 | INHERITED FROM: Diacylglycerol kinase (ATP) || Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| ADP-ribosylation | 1 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || 2'-phosphotransferase || 1-phosphatidylinositol 4-kinase |
| BRCT domain | 1 | INHERITED FROM: DNA nucleotidylexotransferase |
| E set domains | 1 | INHERITED FROM: Nucleotidyltransferases || Receptor protein-tyrosine kinase || Protein-tyrosine kinases || RNA-directed RNA polymerase |
| Phosphoglucomutase, C-terminal domain | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| PRTase-like | 1 | INHERITED FROM: Ribose-phosphate diphosphokinase || Diphosphotransferases || Uridine kinase |
| SGNH hydrolase | 1 | INHERITED FROM: N-acylneuraminate cytidylyltransferase |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: Polynucleotide adenylyltransferase || RNA uridylyltransferase |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Shikimate kinase |
| Aldolase | 1 | INHERITED FROM: Shikimate kinase |
| Sec63 N-terminal domain-like | 1 | INHERITED FROM: DNA-directed DNA polymerase |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | INHERITED FROM: Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase |
| UDP-Glycosyltransferase/glycogen phosphorylase | 1 | INHERITED FROM: Teichoic acid poly(glycerol phosphate) polymerase || Teichoic acid glycerol-phosphate primase || N-acylmannosamine kinase |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
| Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| SIS domain | 1 | INHERITED FROM: Glucokinase |
| Phosphoglycerate mutase-like | 1 | INHERITED FROM: Diphosphoinositol-pentakisphosphate kinase || 6-phosphofructo-2-kinase || Inositol-hexakisphosphate kinase |
| RmlC-like cupins | 1 | INHERITED FROM: Mannose-1-phosphate guanylyltransferase |
| Translation proteins | 1 | INHERITED FROM: Nucleotidyltransferases || Sulfate adenylyltransferase || Adenylyl-sulfate kinase |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: mRNA guanylyltransferase |
| Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: Pyruvate, phosphate dikinase || Diphosphoinositol-pentakisphosphate kinase || Inositol-tetrakisphosphate 1-kinase || Phosphotransferases with paired acceptors || Inositol-1,3,4-trisphosphate 5/6-kinase || Inositol-hexakisphosphate kinase || Pyruvate, water dikinase |
| TGS-like | 1 | INHERITED FROM: GTP diphosphokinase || Diphosphotransferases |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Shikimate kinase || Aspartate kinase |
| dUTPase-like | 1 | INHERITED FROM: DNA-directed DNA polymerase || RNA-directed DNA polymerase |
| Galactose-binding domain-like | 1 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases |
| Dehydroquinate synthase-like | 1 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || Shikimate kinase |
| Thiamin phosphate synthase | 1 | INHERITED FROM: Hydroxymethylpyrimidine kinase || Phosphooxymethylpyrimidine kinase |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | INHERITED FROM: 6-phosphofructokinase |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Phosphohistidine domain | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| PH domain-like | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| HPr-like | 0 | Direct |
| Plexin repeat | 0 | Direct |
| PUA domain-like | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Retrovirus capsid dimerization domain-like | 0 | Direct |
| Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
| EF-hand | 0 | Direct |
| KA1-like | 0 | Direct |
| YrdC/RibB | 0 | Direct |
| ApbE-like | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| L domain-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
| DNA polymerase III chi subunit | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| HAMP domain-like | 0 | Direct |
| CheW-like | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| SH3-domain | 0 | Direct |
| PPK N-terminal domain-like | 0 | Direct |
| Riboflavin kinase-like | 0 | Direct |
| TAF(II)230 TBP-binding fragment | 0 | Direct |
| EndoU-like | 0 | Direct |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Retroviral matrix proteins | 0 | Direct |
| DAK1/DegV-like | 0 | Direct |
| PK C-terminal domain-like | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| alpha-D-mannose-specific plant lectins | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| Glycerate kinase I | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| ACT-like | 0 | Direct |
| Ribonuclease H-like | 0 | Direct |
| Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
| BAR/IMD domain-like | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| YgbK-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| RNI-like | 0 | Direct |
| PTS system fructose IIA component-like | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| Polo-box domain | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| Sporulation response regulatory protein Spo0B | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| Trypsin-like serine proteases | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| Acid proteases | 0 | Direct |
| RNA polymerase subunit RPB10 | 0 | Direct |
| RPB5-like RNA polymerase subunit | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| PsbU/PolX domain-like | 0 | Direct |
| PTS IIb component | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Fic-like | 0 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
| PHP domain-like | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| Immunoglobulin | 0 | Direct |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | Direct |
| Insert subdomain of RNA polymerase alpha subunit | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| PHP14-like | 0 | Direct |
| SH2 domain | 0 | Direct |
| Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Sema domain | 0 | Direct |
| Glucose permease domain IIB | 0 | Direct |
| Phosphoglycerate kinase | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| CheY-binding domain of CheA | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| L27 domain | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| Notch domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| Trm112p-like | 0 | Direct |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
| Thiamin pyrophosphokinase, catalytic domain | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| PTS system IIB component-like | 0 | Direct |
| AF1531-like | 0 | Direct |
| Poly(A) polymerase catalytic subunit-like | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| Sensory domain-like | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| CofD-like | 0 | Direct |
| FAT domain of focal adhesion kinase | 0 | Direct |
| GAF domain-like | 0 | Direct |
| YojJ-like | 0 | Direct |
| Protein kinase-like (PK-like) | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| SAM/Pointed domain | 0 | Direct |
| C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| Carbamate kinase-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| RPB6/omega subunit-like | 0 | Direct |
| Poly A polymerase C-terminal region-like | 0 | Direct |
| DhaL-like | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0.00000000000001193 | Direct |
| CheY-like | 0.000000000001922 | Direct |
| ARM repeat | 0.000000000006522 | Direct |
| Replicase NSP9 | 0.00000000001027 | Direct |
| Coronavirus NSP10-like | 0.00000000001027 | Direct |
| Coronavirus NSP8-like | 0.00000000001027 | Direct |
| Coronavirus NSP7-like | 0.00000000001027 | Direct |
| Ubiquitin-like | 0.0000000001648 | Direct |
| RNA polymerase subunits | 0.0000000001848 | Direct |
| Duplicated hybrid motif | 0.0000000003566 | Direct |
| GckA/TtuD-like | 0.000000002487 | Direct |
| HD-domain/PDEase-like | 0.000000008509 | Direct |
| NSP3A-like | 0.0000000541 | Direct |
| PX domain | 0.00000005433 | Direct |
| Hedgehog/intein (Hint) domain | 0.0000006691 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0.000004199 | Direct |
| GroEL apical domain-like | 0.000006709 | Direct |
| Second domain of FERM | 0.00001163 | Direct |
| CRAL/TRIO domain | 0.00001322 | Direct |
| YWTD domain | 0.00001811 | Direct |
| beta-sandwich domain of Sec23/24 | 0.00003643 | Direct |
| Glutamine synthetase/guanido kinase | 0.00006841 | Direct |
| DEATH domain | 0.0001123 | Direct |
| IpsF-like | 0.0001406 | Direct |
| NTF2-like | 0.0001777 | Direct |
| Homing endonucleases | 0.0002917 | Direct |
| MIT domain | 0.0006833 | Direct |
| SARS Nsp1-like | 0.003921 | Inherited |
| Myosin rod fragments | 0.005558 | Inherited |
| HIT-like | 0.006852 | Inherited |
| GTPase activation domain, GAP | 0.007601 | Inherited |
| Chaperone J-domain | 0.007985 | Inherited |
| TPR-like | 0.009254 | Inherited |
| Molybdenum cofactor biosynthesis proteins | 0.01066 | Inherited |
| PDZ domain-like | 0.01085 | Inherited |
| Nucleic acid-binding proteins | 0.01358 | Inherited |
| C-terminal domain of transcriptional repressors | 0.02807 | Inherited |
| Rubredoxin-like | 0.03057 | Inherited |
| GroEL-intermediate domain like | 0.04421 | Inherited |
| HCP-like | 0.04428 | Inherited |
| cAMP-binding domain-like | 0.05607 | Inherited |
| RCC1/BLIP-II | 0.0618 | Inherited |
| C-type lectin-like | 0.06839 | Inherited |
| CYTH-like phosphatases | 0.1029 | Inherited |
| Nucleotide cyclase | 0.1069 | Inherited |
| SMAD/FHA domain | 0.131 | Inherited |
| SCOP hierarchy in SUPERFAMILY | 0.1877 | Inherited |
| WD40 repeat-like | 0.2833 | Inherited |
| Macro domain-like | 0.3529 | Inherited |
| SAICAR synthase-like | 0.5358 | Inherited |
| Cyclin-like | 0.6034 | Inherited |
| Homeodomain-like | 0.7071 | Inherited |
| MoeA N-terminal region -like | 0.7521 | Inherited |
| MoeA C-terminal domain-like | 0.7521 | Inherited |
| Zinc beta-ribbon | 0.769 | Inherited |
| UBA-like | 0.7762 | Inherited |
| PurM N-terminal domain-like | 0.7838 | Inherited |
| Globin-like | 0.7873 | Inherited |
| PurM C-terminal domain-like | 0.7897 | Inherited |
| Galactose oxidase, central domain | 0.8163 | Inherited |
| Ribonuclease Rh-like | 0.881 | Inherited |
| Kringle-like | 0.9785 | Inherited |
| EPT/RTPC-like | 1 | Inherited |
| Cysteine proteinases | 1 | Inherited |
| "Winged helix" DNA-binding domain | 1 | Inherited |
| Thioredoxin-like | 1 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 1 | Inherited |
| DNase I-like | 1 | Inherited |
| ALDH-like | 1 | Inherited |
| Concanavalin A-like lectins/glucanases | 1 | Inherited |
| RuvA domain 2-like | 1 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | Inherited |
| Dihydropteroate synthetase-like | 1 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | Inherited |
| Nudix | 1 | Inherited |
| FYVE/PHD zinc finger | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| Heme oxygenase-like | 1 | Inherited |
| RNA-binding domain, RBD | 1 | Inherited |
| Phosphoenolpyruvate/pyruvate domain | 1 | Inherited |
| HAD-like | 1 | Inherited |
| Clavaminate synthase-like | 1 | Inherited |
| Bromodomain | 1 | Inherited |
| Adenine nucleotide alpha hydrolases-like | 1 | Inherited |
| lambda repressor-like DNA-binding domains | 1 | Inherited |
| Ankyrin repeat | 1 | Inherited |
| ADP-ribosylation | 1 | Inherited |
| BRCT domain | 1 | Inherited |
| E set domains | 1 | Inherited |
| Phosphoglucomutase, C-terminal domain | 1 | Inherited |
| PRTase-like | 1 | Inherited |
| SGNH hydrolase | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Aldolase | 1 | Inherited |
| Sec63 N-terminal domain-like | 1 | Inherited |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 1 | Inherited |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 1 | Inherited |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 1 | Inherited |
| Phosphoglucomutase, first 3 domains | 1 | Inherited |
| SIS domain | 1 | Inherited |
| Phosphoglycerate mutase-like | 1 | Inherited |
| RmlC-like cupins | 1 | Inherited |
| Translation proteins | 1 | Inherited |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
| TGS-like | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| dUTPase-like | 1 | Inherited |
| Galactose-binding domain-like | 1 | Inherited |
| Dehydroquinate synthase-like | 1 | Inherited |
| Thiamin phosphate synthase | 1 | Inherited |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | Inherited |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this EC term (Not in SDEC)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| alpha-D-mannose-specific plant lectins | 0 | DIRECT |
| Archaeal tRNA CCA-adding enzyme | 0 | DIRECT |
| BphP N-terminal domain-like | 0 | DIRECT |
| HTLV-II matrix protein | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| KaiB-like | 0 | DIRECT |
| CofD-like | 0 | DIRECT |
| RNA polymerase omega subunit | 0 | DIRECT |
| Thiamin pyrophosphokinase, catalytic domain | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| DNA polymerase beta-like, second domain | 0 | DIRECT |
| PTS system, Fructose specific IIB subunit-like | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| GrpB-like | 0 | DIRECT |
| YgbK-like | 0 | DIRECT |
| CoaX-like | 0 | DIRECT |
| Polygalacturonase inhibiting protein PGIP | 0 | DIRECT |
| T7 RNA polymerase | 0 | DIRECT |
| Ras-binding domain, RBD | 0 | DIRECT |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | DIRECT |
| DhaL-like | 0 | DIRECT |
| RIO1-like kinases | 0 | DIRECT |
| Fumble-like | 0 | DIRECT |
| PPK middle domain-like | 0 | DIRECT |
| PTS IIb component | 0 | DIRECT |
| Viral proteases | 0 | DIRECT |
| AF1531-like | 0 | DIRECT |
| PyrH-like | 0 | DIRECT |
| Ssp2 C-terminal domain-like | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Protein kinases, catalytic subunit | 0 | DIRECT |
| ADP-specific Phosphofructokinase/Glucokinase | 0 | DIRECT |
| Receiver domain of the ethylene receptor | 0 | DIRECT |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | DIRECT |
| Sensory domain of two-component sensor kinase | 0 | DIRECT |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
| Viral cysteine protease of trypsin fold | 0 | DIRECT |
| Chemotaxis protein CheA P1 domain | 0 | DIRECT |
| Pyruvate phosphate dikinase, N-terminal domain | 0 | DIRECT |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
| FCH domain | 0 | DIRECT |
| Ribonuclease PH domain 1-like | 0 | DIRECT |
| L domain | 0 | DIRECT |
| Archaeal tRNA CCA-adding enzyme substrate-binding domain | 0 | DIRECT |
| PB1 domain | 0 | DIRECT |
| Myosin rod fragments | 0 | DIRECT |
| ROK | 0 | DIRECT |
| Archaeal tRNA CCA-adding enzyme catalytic domain | 0 | DIRECT |
| IIA domain of mannitol-specific and ntr phosphotransferase EII | 0 | DIRECT |
| DNA polymerase I | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| Sporulation response regulatory protein Spo0B | 0 | DIRECT |
| HAMP domain | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| RpiR-like | 0 | DIRECT |
| Shikimate kinase (AroK) | 0 | DIRECT |
| 5' to 3' exonuclease catalytic domain | 0 | DIRECT |
| 4'-Phosphopantetheinyl transferase SFP | 0 | DIRECT |
| Adenylyltransferase | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| DNA polymerase III chi subunit | 0 | DIRECT |
| Adenosine-5'phosphosulfate kinase (APS kinase) | 0 | DIRECT |
| RPB6 | 0 | DIRECT |
| CTP-dependent riboflavin kinase-like | 0 | DIRECT |
| Choline kinase | 0 | DIRECT |
| FMDV leader protease | 0 | DIRECT |
| 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase IspE | 0 | DIRECT |
| Insert subdomain of RNA polymerase alpha subunit | 0 | DIRECT |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
| RNA helicase | 0 | DIRECT |
| RNA-polymerase beta-prime | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| Type II thymidine kinase | 0 | DIRECT |
| Glucokinase | 0 | DIRECT |
| Swapped Polo-box domain | 0 | DIRECT |
| PAPS reductase-like | 0 | DIRECT |
| Polo-box duplicated region | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| DNA polymerase beta-like | 0 | DIRECT |
| GlmU C-terminal domain-like | 0 | DIRECT |
| Gluconate kinase | 0 | DIRECT |
| ATP sulfurylase catalytic domain | 0 | DIRECT |
| Glucose permease domain IIB | 0 | DIRECT |
| GHMP Kinase, N-terminal domain | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| Nsp15 N-terminal domain-like | 0 | DIRECT |
| Retrovirus capsid protein C-terminal domain | 0 | DIRECT |
| FAT domain of focal adhesion kinase | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| Cold shock DNA-binding domain-like | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| Calmodulin-like | 0 | DIRECT |
| MarR-like transcriptional regulators | 0 | DIRECT |
| Legume lectins | 0 | DIRECT |
| Glycerol kinase | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| beta-lactamase inhibitor protein-II, BLIP-II | 0 | DIRECT |
| RelA/SpoT domain | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| RNA polymerase subunit RPB10 | 0 | DIRECT |
| Molybdenum cofactor biosynthesis protein MobA | 0 | DIRECT |
| GGDEF domain | 0 | DIRECT |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| I set domains | 0 | DIRECT |
| Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Molybdenum cofactor biosynthesis protein MoeB | 0 | DIRECT |
| RBP11/RpoL | 0 | DIRECT |
| Class II viral fusion proteins C-terminal domain | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| V set domains (antibody variable domain-like) | 0 | DIRECT |
| mRNA capping enzyme | 0 | DIRECT |
| Phosphoribosylpyrophosphate synthetase-like | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | DIRECT |
| Immunodeficiency virus matrix proteins | 0 | DIRECT |
| Pyruvate phosphate dikinase, C-terminal domain | 0 | DIRECT |
| DAK1 | 0 | DIRECT |
| Caliciviridae-like VP | 0 | DIRECT |
| Cytidylytransferase | 0 | DIRECT |
| Polyphosphate kinase C-terminal domain | 0 | DIRECT |
| Phosphoglycerate kinase | 0 | DIRECT |
| Nsp15 C-terminal domain-like | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| MHCK/EF2 kinase | 0 | DIRECT |
| Trm112p-like | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Glycerate kinase I | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| PTS system, Lactose/Cellobiose specific IIB subunit | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| YojJ-like | 0 | DIRECT |
| Pyruvate kinase beta-barrel domain | 0 | DIRECT |
| ATP sulfurylase N-terminal domain | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | DIRECT |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | DIRECT |
| mannose-1-phosphate guanylyl transferase | 0 | DIRECT |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | DIRECT |
| Nucleotide and nucleoside kinases | 0 | DIRECT |
| Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
| Fic-like | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system | 0 | DIRECT |
| GAG polyprotein M-domain | 0 | DIRECT |
| Phosphoribulokinase/pantothenate kinase | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| RPB5 | 0 | DIRECT |
| Phytochrome-specific domain | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | DIRECT |
| Retroviral integrase, catalytic domain | 0 | DIRECT |
| Homoserine kinase | 0 | DIRECT |
| DhaM-like | 0 | DIRECT |
| MMLV matrix protein-like | 0 | DIRECT |
| Hexokinase | 0 | DIRECT |
| Poly(A) polymerase, PAP, middle domain | 0 | DIRECT |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | DIRECT |
| Glucose permease-like | 0 | DIRECT |
| TAF(II)230 TBP-binding fragment | 0 | DIRECT |
| CheW-like | 0 | DIRECT |
| Carbamate kinase | 0 | DIRECT |
| Thiamin biosynthesis kinases | 0 | DIRECT |
| Histidine kinase | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| APH phosphotransferases | 0 | DIRECT |
| Cytidylyltransferase | 0 | DIRECT |
| Pyruvate kinase, C-terminal domain | 0 | DIRECT |
| glucose-1-phosphate thymidylyltransferase | 0 | DIRECT |
| Galactokinase | 0 | DIRECT |
| ApbE-like | 0 | DIRECT |
| N-acetyl-l-glutamate kinase | 0 | DIRECT |
| NAD kinase-like | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | DIRECT |
| Poxvirus poly(A) polymerase catalytic subunit-like | 0 | DIRECT |
| Plasmid maintenance system epsilon/zeta, toxin zeta subunit | 0 | DIRECT |
| Holo-(acyl carrier protein) synthase ACPS | 0 | DIRECT |
| Macro domain | 0 | DIRECT |
| Poly A polymerase C-terminal region-like | 0 | DIRECT |
| Hexose-1-phosphate uridylyltransferase | 0 | DIRECT |
| C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
| Kinase associated domain 1, KA1 | 0 | DIRECT |
| Pyruvate phosphate dikinase, central domain | 0 | DIRECT |
| RhoA-binding domain | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| Acetokinase-like | 0 | DIRECT |
| Reverse transcriptase | 0 | DIRECT |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| ATP-dependent riboflavin kinase-like | 0 | DIRECT |
| Flavin-binding PAS domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | DIRECT |
| Pyruvate kinase | 0 | DIRECT |
| GlnE-like domain | 0 | DIRECT |
| YrdC-like | 0 | DIRECT |
| Aspartokinase allosteric domain-like | 0 | DIRECT |
| Extracellular domain of cell surface receptors | 0 | DIRECT |
| Glutamine synthase adenylyltransferase GlnE, domain 2 | 0 | DIRECT |
| DEP domain | 0 | DIRECT |
| RcsC linker domain-like | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| Retroviral protease (retropepsin) | 0 | DIRECT |
| RNA polymerase alpha subunit dimerisation domain | 0 | DIRECT |
| MM2497-like | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| YWTD domain | 0 | DIRECT |
| RNA-polymerase beta | 0 | DIRECT |
| Diacylglycerol kinase-like | 0 | DIRECT |
| RNA-dependent RNA-polymerase | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
| CheY-binding domain of CheA | 0 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
| ATP sulfurylase C-terminal domain | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Mevalonate kinase | 0 | DIRECT |
| Guanido kinase catalytic domain | 0 | DIRECT |
| LuxQ-periplasmic domain-like | 0 | DIRECT |
| Type II thymidine kinase zinc finger | 0 | DIRECT |
| HPr-like | 0 | DIRECT |
| Synaptotagmin-like (S variant) | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Ephrin receptor ligand binding domain | 0 | DIRECT |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
| PPK N-terminal domain-like | 0 | DIRECT |
| Tpt1/KptA | 0 | DIRECT |
| Poly A polymerase head domain-like | 0 | DIRECT |
| UDP-glucose pyrophosphorylase | 0 | DIRECT |
| SAM (sterile alpha motif) domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| PfkB-like kinase | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| mRNA cap methylase | 1.855e-16 | DIRECT |
| PHP domain | 0.000000000002312 | DIRECT |
| Coronavirus NSP7-like | 0.000000000006567 | DIRECT |
| Coronavirus NSP10-like | 0.000000000006567 | DIRECT |
| Coronavirus NSP8-like | 0.000000000006567 | DIRECT |
| Replicase NSP9 | 0.000000000006567 | DIRECT |
| Heme-binding PAS domain | 0.00000000002437 | DIRECT |
| MogA-like | 0.00000000004622 | DIRECT |
| GAF domain | 0.00000000004937 | DIRECT |
| Ngr ectodomain-like | 0.0000000004619 | DIRECT |
| PX domain | 0.000000006382 | DIRECT |
| GckA/TtuD-like | 0.00000001086 | DIRECT |
| HD domain | 0.00000002826 | DIRECT |
| NSP3A-like | 0.00000003785 | DIRECT |
| LIM domain | 0.00000004468 | DIRECT |
| phosphatase domain of polynucleotide kinase | 0.000002067 | DIRECT |
| Elongation factors | 0.0000029 | DIRECT |
| BadF/BadG/BcrA/BcrD-like | 0.00001012 | DIRECT |
| PLC-like (P variant) | 0.00002132 | DIRECT |
| Second domain of FERM | 0.00005289 | DIRECT |
| Mason-Pfizer monkey virus matrix protein | 0.00009121 | DIRECT |
| Probable phosphatase YrbI | 0.00009121 | DIRECT |
| IpsF-like | 0.00009307 | DIRECT |
| MIT domain | 0.0002203 | DIRECT |
| Intein (protein splicing domain) | 0.001664 | INHERITED FROM: Nucleotidyltransferases || DNA-directed DNA polymerase |
| Homoserine dehydrogenase-like | 0.002096 | INHERITED FROM: Aspartate kinase || Phosphotransferases with a carboxy group as acceptor |
| SARS Nsp1-like | 0.003226 | INHERITED FROM: Nucleotidyltransferases || RNA-directed RNA polymerase |
| CheY-related | 0.003964 | INHERITED FROM: Protein-histidine kinases |
| BCR-homology GTPase activation domain (BH-domain) | 0.006313 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Motor proteins | 0.00662 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Chaperone J-domain | 0.006664 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| RWD domain | 0.01044 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| cAMP-binding domain | 0.01643 | INHERITED FROM: Protein-serine/threonine kinases || cGMP-dependent protein kinase |
| Biotin repressor (BirA) | 0.02389 | INHERITED FROM: Pantothenate kinase || Phosphotransferases with an alcohol group as acceptor |
| TENA/THI-4 | 0.02393 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || Hydroxymethylpyrimidine kinase || Phosphooxymethylpyrimidine kinase || Phosphotransferases with a phosphate group as acceptor |
| Quinoprotein alcohol dehydrogenase-like | 0.02563 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| First domain of FERM | 0.0522 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
| Third domain of FERM | 0.0522 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
| Sulfatase-modifying factor-like | 0.08648 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| AlkB-like | 0.08819 | INHERITED FROM: Nucleotidyltransferases || RNA-directed RNA polymerase |
| FHA domain | 0.1469 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| EF-hand modules in multidomain proteins | 0.1903 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || Diacylglycerol kinase (ATP) |
| Biotin holoenzyme synthetase | 0.1936 | INHERITED FROM: Pantothenate kinase |
| Regulator of chromosome condensation RCC1 | 0.2089 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| UDP-N-acetylglucosamine 2-epimerase | 0.2445 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || N-acylmannosamine kinase |
| PDZ domain | 0.3293 | INHERITED FROM: Protein-serine/threonine kinases |
| DHN aldolase/epimerase | 0.3769 | INHERITED FROM: Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.4466 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || 1-phosphatidylinositol-3-phosphate 5-kinase |
| Canonical RBD | 0.5495 | INHERITED FROM: Polynucleotide adenylyltransferase || RNA uridylyltransferase |
| DNase I-like | 0.551 | INHERITED FROM: RNA-directed DNA polymerase |
| UBA domain | 0.5777 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Achaeal helicase C-terminal domain | 0.6065 | INHERITED FROM: DNA-directed DNA polymerase |
| Caspase recruitment domain, CARD | 0.6388 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase || Non-specific serine/threonine protein kinase |
| Ubiquitin-related | 0.6845 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || 1-phosphatidylinositol 4-kinase |
| Kringle modules | 0.7069 | INHERITED FROM: Receptor protein-tyrosine kinase || Protein-tyrosine kinases |
| MoeA C-terminal domain-like | 0.7195 | INHERITED FROM: Nucleotidyltransferases || Molybdopterin adenylyltransferase |
| PurM N-terminal domain-like | 0.7328 | INHERITED FROM: Thiamine-phosphate kinase || Phosphotransferases with paired acceptors || Selenide, water dikinase |
| PurM C-terminal domain-like | 0.7383 | INHERITED FROM: Thiamine-phosphate kinase || Phosphotransferases with paired acceptors || Selenide, water dikinase |
| MoeA N-terminal region -like | 0.7868 | INHERITED FROM: Nucleotidyltransferases || Molybdopterin adenylyltransferase |
| MoeA central domain-like | 0.7868 | INHERITED FROM: Nucleotidyltransferases || Molybdopterin adenylyltransferase |
| Ribonuclease Rh-like | 0.8206 | INHERITED FROM: RNA-directed RNA polymerase |
| Globins | 0.8565 | INHERITED FROM: Diguanylate cyclase |
| G proteins | 0.9457 | INHERITED FROM: Nucleotidyltransferases || Sulfate adenylyltransferase || Adenylyl-sulfate kinase |
| WD40-repeat | 0.9516 | INHERITED FROM: [Myosin heavy-chain] kinase || Protein-serine/threonine kinases |
| Shikimate dehydrogenase-like | 0.9909 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || Shikimate kinase |
| mRNA cap (Guanine N-7) methyltransferase | 1 | INHERITED FROM: mRNA guanylyltransferase |
| Ribonuclease H | 1 | INHERITED FROM: Nucleotidyltransferases || DNA-directed DNA polymerase || RNA-directed DNA polymerase |
| ALDH-like | 1 | INHERITED FROM: Glutamate 5-kinase |
| Tetratricopeptide repeat (TPR) | 1 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| PHD domain | 1 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
| Bromodomain | 1 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase || Non-specific serine/threonine protein kinase |
| Dual specificity phosphatase-like | 1 | INHERITED FROM: mRNA guanylyltransferase |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 1 | INHERITED FROM: mRNA guanylyltransferase |
| Class I aldolase | 1 | INHERITED FROM: Shikimate kinase |
| Dehydroquinate synthase, DHQS | 1 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || Shikimate kinase |
| mono-SIS domain | 1 | INHERITED FROM: Glucokinase |
| Aminoacid dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Shikimate kinase |
| RecA protein-like (ATPase-domain) | 1 | INHERITED FROM: Adenosylcobinamide-phosphate guanylyltransferase || Adenosylcobinamide kinase |
| Ankyrin repeat | 1 | INHERITED FROM: Diacylglycerol kinase (ATP) || Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Enolpyruvate transferase, EPT | 1 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || Shikimate kinase |
| Phosphoribosyltransferases (PRTases) | 1 | INHERITED FROM: Uridine kinase |
| MutT-like | 1 | INHERITED FROM: ADP-D-ribose pyrophosphorylase |
| Dihydropteroate synthetase | 1 | INHERITED FROM: Diphosphotransferases || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
| Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) | 1 | INHERITED FROM: Phosphotransferases with a phosphate group as acceptor || (d)CMP kinase |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
| Nitrogenase iron protein-like | 1 | INHERITED FROM: Non-specific protein-tyrosine kinase |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
| Thiamin phosphate synthase | 1 | INHERITED FROM: Hydroxymethylpyrimidine kinase || Phosphooxymethylpyrimidine kinase |
| dUTPase-like | 1 | INHERITED FROM: DNA-directed DNA polymerase || RNA-directed DNA polymerase |
| Extended AAA-ATPase domain | 1 | INHERITED FROM: DNA-directed DNA polymerase |
| Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| alpha-D-mannose-specific plant lectins | 0 | Direct |
| Archaeal tRNA CCA-adding enzyme | 0 | Direct |
| BphP N-terminal domain-like | 0 | Direct |
| HTLV-II matrix protein | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| KaiB-like | 0 | Direct |
| CofD-like | 0 | Direct |
| RNA polymerase omega subunit | 0 | Direct |
| Thiamin pyrophosphokinase, catalytic domain | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| DNA polymerase beta-like, second domain | 0 | Direct |
| PTS system, Fructose specific IIB subunit-like | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| GrpB-like | 0 | Direct |
| YgbK-like | 0 | Direct |
| CoaX-like | 0 | Direct |
| Polygalacturonase inhibiting protein PGIP | 0 | Direct |
| T7 RNA polymerase | 0 | Direct |
| Ras-binding domain, RBD | 0 | Direct |
| Poly(A) polymerase, PAP, N-terminal domain | 0 | Direct |
| DhaL-like | 0 | Direct |
| RIO1-like kinases | 0 | Direct |
| Fumble-like | 0 | Direct |
| PPK middle domain-like | 0 | Direct |
| PTS IIb component | 0 | Direct |
| Viral proteases | 0 | Direct |
| AF1531-like | 0 | Direct |
| PyrH-like | 0 | Direct |
| Ssp2 C-terminal domain-like | 0 | Direct |
| Plexin repeat | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Protein kinases, catalytic subunit | 0 | Direct |
| ADP-specific Phosphofructokinase/Glucokinase | 0 | Direct |
| Receiver domain of the ethylene receptor | 0 | Direct |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | Direct |
| Sensory domain of two-component sensor kinase | 0 | Direct |
| Poly(A) polymerase, PAP, C-terminal domain | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
| Viral cysteine protease of trypsin fold | 0 | Direct |
| Chemotaxis protein CheA P1 domain | 0 | Direct |
| Pyruvate phosphate dikinase, N-terminal domain | 0 | Direct |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
| FCH domain | 0 | Direct |
| Ribonuclease PH domain 1-like | 0 | Direct |
| L domain | 0 | Direct |
| Archaeal tRNA CCA-adding enzyme substrate-binding domain | 0 | Direct |
| PB1 domain | 0 | Direct |
| Myosin rod fragments | 0 | Direct |
| ROK | 0 | Direct |
| Archaeal tRNA CCA-adding enzyme catalytic domain | 0 | Direct |
| IIA domain of mannitol-specific and ntr phosphotransferase EII | 0 | Direct |
| DNA polymerase I | 0 | Direct |
| SH2 domain | 0 | Direct |
| Sporulation response regulatory protein Spo0B | 0 | Direct |
| HAMP domain | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| L27 domain | 0 | Direct |
| RpiR-like | 0 | Direct |
| Shikimate kinase (AroK) | 0 | Direct |
| 5' to 3' exonuclease catalytic domain | 0 | Direct |
| 4'-Phosphopantetheinyl transferase SFP | 0 | Direct |
| Adenylyltransferase | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| DNA polymerase III chi subunit | 0 | Direct |
| Adenosine-5'phosphosulfate kinase (APS kinase) | 0 | Direct |
| RPB6 | 0 | Direct |
| CTP-dependent riboflavin kinase-like | 0 | Direct |
| Choline kinase | 0 | Direct |
| FMDV leader protease | 0 | Direct |
| 4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase IspE | 0 | Direct |
| Insert subdomain of RNA polymerase alpha subunit | 0 | Direct |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
| RNA helicase | 0 | Direct |
| RNA-polymerase beta-prime | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| Type II thymidine kinase | 0 | Direct |
| Glucokinase | 0 | Direct |
| Swapped Polo-box domain | 0 | Direct |
| PAPS reductase-like | 0 | Direct |
| Polo-box duplicated region | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| DNA polymerase beta-like | 0 | Direct |
| GlmU C-terminal domain-like | 0 | Direct |
| Gluconate kinase | 0 | Direct |
| ATP sulfurylase catalytic domain | 0 | Direct |
| Glucose permease domain IIB | 0 | Direct |
| GHMP Kinase, N-terminal domain | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| Nsp15 N-terminal domain-like | 0 | Direct |
| Retrovirus capsid protein C-terminal domain | 0 | Direct |
| FAT domain of focal adhesion kinase | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| Cold shock DNA-binding domain-like | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| Calmodulin-like | 0 | Direct |
| MarR-like transcriptional regulators | 0 | Direct |
| Legume lectins | 0 | Direct |
| Glycerol kinase | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| beta-lactamase inhibitor protein-II, BLIP-II | 0 | Direct |
| RelA/SpoT domain | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| RNA polymerase subunit RPB10 | 0 | Direct |
| Molybdenum cofactor biosynthesis protein MobA | 0 | Direct |
| GGDEF domain | 0 | Direct |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| I set domains | 0 | Direct |
| Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Molybdenum cofactor biosynthesis protein MoeB | 0 | Direct |
| RBP11/RpoL | 0 | Direct |
| Class II viral fusion proteins C-terminal domain | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| V set domains (antibody variable domain-like) | 0 | Direct |
| mRNA capping enzyme | 0 | Direct |
| Phosphoribosylpyrophosphate synthetase-like | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | Direct |
| Immunodeficiency virus matrix proteins | 0 | Direct |
| Pyruvate phosphate dikinase, C-terminal domain | 0 | Direct |
| DAK1 | 0 | Direct |
| Caliciviridae-like VP | 0 | Direct |
| Cytidylytransferase | 0 | Direct |
| Polyphosphate kinase C-terminal domain | 0 | Direct |
| Phosphoglycerate kinase | 0 | Direct |
| Nsp15 C-terminal domain-like | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| MHCK/EF2 kinase | 0 | Direct |
| Trm112p-like | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Glycerate kinase I | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| PTS system, Lactose/Cellobiose specific IIB subunit | 0 | Direct |
| Notch domain | 0 | Direct |
| YojJ-like | 0 | Direct |
| Pyruvate kinase beta-barrel domain | 0 | Direct |
| ATP sulfurylase N-terminal domain | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, second domain | 0 | Direct |
| Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) | 0 | Direct |
| mannose-1-phosphate guanylyl transferase | 0 | Direct |
| 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain | 0 | Direct |
| Nucleotide and nucleoside kinases | 0 | Direct |
| Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
| Fic-like | 0 | Direct |
| HR1 repeat | 0 | Direct |
| N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system | 0 | Direct |
| GAG polyprotein M-domain | 0 | Direct |
| Phosphoribulokinase/pantothenate kinase | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| RPB5 | 0 | Direct |
| Phytochrome-specific domain | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, C-terminal domain | 0 | Direct |
| Retroviral integrase, catalytic domain | 0 | Direct |
| Homoserine kinase | 0 | Direct |
| DhaM-like | 0 | Direct |
| MMLV matrix protein-like | 0 | Direct |
| Hexokinase | 0 | Direct |
| Poly(A) polymerase, PAP, middle domain | 0 | Direct |
| Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A | 0 | Direct |
| Glucose permease-like | 0 | Direct |
| TAF(II)230 TBP-binding fragment | 0 | Direct |
| CheW-like | 0 | Direct |
| Carbamate kinase | 0 | Direct |
| Thiamin biosynthesis kinases | 0 | Direct |
| Histidine kinase | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| APH phosphotransferases | 0 | Direct |
| Cytidylyltransferase | 0 | Direct |
| Pyruvate kinase, C-terminal domain | 0 | Direct |
| glucose-1-phosphate thymidylyltransferase | 0 | Direct |
| Galactokinase | 0 | Direct |
| ApbE-like | 0 | Direct |
| N-acetyl-l-glutamate kinase | 0 | Direct |
| NAD kinase-like | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0 | Direct |
| Poxvirus poly(A) polymerase catalytic subunit-like | 0 | Direct |
| Plasmid maintenance system epsilon/zeta, toxin zeta subunit | 0 | Direct |
| Holo-(acyl carrier protein) synthase ACPS | 0 | Direct |
| Macro domain | 0 | Direct |
| Poly A polymerase C-terminal region-like | 0 | Direct |
| Hexose-1-phosphate uridylyltransferase | 0 | Direct |
| C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
| Kinase associated domain 1, KA1 | 0 | Direct |
| Pyruvate phosphate dikinase, central domain | 0 | Direct |
| RhoA-binding domain | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| Acetokinase-like | 0 | Direct |
| Reverse transcriptase | 0 | Direct |
| RNA editing terminal uridyl transferase 2, RET2, domain 2 | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| ATP-dependent riboflavin kinase-like | 0 | Direct |
| Flavin-binding PAS domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), catalytic domain | 0 | Direct |
| Pyruvate kinase | 0 | Direct |
| GlnE-like domain | 0 | Direct |
| YrdC-like | 0 | Direct |
| Aspartokinase allosteric domain-like | 0 | Direct |
| Extracellular domain of cell surface receptors | 0 | Direct |
| Glutamine synthase adenylyltransferase GlnE, domain 2 | 0 | Direct |
| DEP domain | 0 | Direct |
| RcsC linker domain-like | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| Retroviral protease (retropepsin) | 0 | Direct |
| RNA polymerase alpha subunit dimerisation domain | 0 | Direct |
| MM2497-like | 0 | Direct |
| SH3-domain | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| YWTD domain | 0 | Direct |
| RNA-polymerase beta | 0 | Direct |
| Diacylglycerol kinase-like | 0 | Direct |
| RNA-dependent RNA-polymerase | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| DnaQ-like 3'-5' exonuclease | 0 | Direct |
| CheY-binding domain of CheA | 0 | Direct |
| Pleckstrin-homology domain (PH domain) | 0 | Direct |
| Cyclin | 0 | Direct |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
| ATP sulfurylase C-terminal domain | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Mevalonate kinase | 0 | Direct |
| Guanido kinase catalytic domain | 0 | Direct |
| LuxQ-periplasmic domain-like | 0 | Direct |
| Type II thymidine kinase zinc finger | 0 | Direct |
| HPr-like | 0 | Direct |
| Synaptotagmin-like (S variant) | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Ephrin receptor ligand binding domain | 0 | Direct |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
| PPK N-terminal domain-like | 0 | Direct |
| Tpt1/KptA | 0 | Direct |
| Poly A polymerase head domain-like | 0 | Direct |
| UDP-glucose pyrophosphorylase | 0 | Direct |
| SAM (sterile alpha motif) domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Sema domain | 0 | Direct |
| PfkB-like kinase | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| mRNA cap methylase | 1.855e-16 | Direct |
| PHP domain | 0.000000000002312 | Direct |
| Coronavirus NSP7-like | 0.000000000006567 | Direct |
| Coronavirus NSP10-like | 0.000000000006567 | Direct |
| Coronavirus NSP8-like | 0.000000000006567 | Direct |
| Replicase NSP9 | 0.000000000006567 | Direct |
| Heme-binding PAS domain | 0.00000000002437 | Direct |
| MogA-like | 0.00000000004622 | Direct |
| GAF domain | 0.00000000004937 | Direct |
| Ngr ectodomain-like | 0.0000000004619 | Direct |
| PX domain | 0.000000006382 | Direct |
| GckA/TtuD-like | 0.00000001086 | Direct |
| HD domain | 0.00000002826 | Direct |
| NSP3A-like | 0.00000003785 | Direct |
| LIM domain | 0.00000004468 | Direct |
| phosphatase domain of polynucleotide kinase | 0.000002067 | Direct |
| Elongation factors | 0.0000029 | Direct |
| BadF/BadG/BcrA/BcrD-like | 0.00001012 | Direct |
| PLC-like (P variant) | 0.00002132 | Direct |
| Second domain of FERM | 0.00005289 | Direct |
| Mason-Pfizer monkey virus matrix protein | 0.00009121 | Direct |
| Probable phosphatase YrbI | 0.00009121 | Direct |
| IpsF-like | 0.00009307 | Direct |
| MIT domain | 0.0002203 | Direct |
| Intein (protein splicing domain) | 0.001664 | Inherited |
| Homoserine dehydrogenase-like | 0.002096 | Inherited |
| SARS Nsp1-like | 0.003226 | Inherited |
| CheY-related | 0.003964 | Inherited |
| BCR-homology GTPase activation domain (BH-domain) | 0.006313 | Inherited |
| Motor proteins | 0.00662 | Inherited |
| Chaperone J-domain | 0.006664 | Inherited |
| RWD domain | 0.01044 | Inherited |
| cAMP-binding domain | 0.01643 | Inherited |
| Biotin repressor (BirA) | 0.02389 | Inherited |
| TENA/THI-4 | 0.02393 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.02563 | Inherited |
| First domain of FERM | 0.0522 | Inherited |
| Third domain of FERM | 0.0522 | Inherited |
| Sulfatase-modifying factor-like | 0.08648 | Inherited |
| AlkB-like | 0.08819 | Inherited |
| FHA domain | 0.1469 | Inherited |
| EF-hand modules in multidomain proteins | 0.1903 | Inherited |
| Biotin holoenzyme synthetase | 0.1936 | Inherited |
| Regulator of chromosome condensation RCC1 | 0.2089 | Inherited |
| UDP-N-acetylglucosamine 2-epimerase | 0.2445 | Inherited |
| PDZ domain | 0.3293 | Inherited |
| DHN aldolase/epimerase | 0.3769 | Inherited |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.4466 | Inherited |
| Canonical RBD | 0.5495 | Inherited |
| DNase I-like | 0.551 | Inherited |
| UBA domain | 0.5777 | Inherited |
| Achaeal helicase C-terminal domain | 0.6065 | Inherited |
| Caspase recruitment domain, CARD | 0.6388 | Inherited |
| Ubiquitin-related | 0.6845 | Inherited |
| Kringle modules | 0.7069 | Inherited |
| MoeA C-terminal domain-like | 0.7195 | Inherited |
| PurM N-terminal domain-like | 0.7328 | Inherited |
| PurM C-terminal domain-like | 0.7383 | Inherited |
| MoeA N-terminal region -like | 0.7868 | Inherited |
| MoeA central domain-like | 0.7868 | Inherited |
| Ribonuclease Rh-like | 0.8206 | Inherited |
| Globins | 0.8565 | Inherited |
| G proteins | 0.9457 | Inherited |
| WD40-repeat | 0.9516 | Inherited |
| Shikimate dehydrogenase-like | 0.9909 | Inherited |
| mRNA cap (Guanine N-7) methyltransferase | 1 | Inherited |
| Ribonuclease H | 1 | Inherited |
| ALDH-like | 1 | Inherited |
| Tetratricopeptide repeat (TPR) | 1 | Inherited |
| PHD domain | 1 | Inherited |
| Bromodomain | 1 | Inherited |
| Dual specificity phosphatase-like | 1 | Inherited |
| DNA ligase/mRNA capping enzyme postcatalytic domain | 1 | Inherited |
| Class I aldolase | 1 | Inherited |
| Dehydroquinate synthase, DHQS | 1 | Inherited |
| mono-SIS domain | 1 | Inherited |
| Aminoacid dehydrogenase-like, C-terminal domain | 1 | Inherited |
| RecA protein-like (ATPase-domain) | 1 | Inherited |
| Ankyrin repeat | 1 | Inherited |
| Enolpyruvate transferase, EPT | 1 | Inherited |
| Phosphoribosyltransferases (PRTases) | 1 | Inherited |
| MutT-like | 1 | Inherited |
| Dihydropteroate synthetase | 1 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) | 1 | Inherited |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 1 | Inherited |
| Nitrogenase iron protein-like | 1 | Inherited |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | Inherited |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 1 | Inherited |
| Thiamin phosphate synthase | 1 | Inherited |
| dUTPase-like | 1 | Inherited |
| Extended AAA-ATPase domain | 1 | Inherited |
| Phosphoglucomutase, first 3 domains | 1 | Inherited |
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A presence/absence matrix is generated using protein domain
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this EC term (SPEC level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
| Tricorn protease domain 2 | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| Phosphofructokinase | 0 | DIRECT |
| Thiamin pyrophosphokinase, catalytic domain | 0 | DIRECT |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
| Retrovirus capsid dimerization domain-like | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| SH2 domain | 0 | DIRECT |
| Ribonuclease H-like | 0 | DIRECT |
| DNA polymerase III chi subunit | 0 | DIRECT |
| PTS system fructose IIA component-like | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
| Growth factor receptor domain | 0 | DIRECT |
| AF1531-like | 0 | DIRECT |
| YrdC/RibB | 0 | DIRECT |
| Fic-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| PHP14-like | 0 | DIRECT |
| SAM/Pointed domain | 0 | DIRECT |
| alpha-D-mannose-specific plant lectins | 0 | DIRECT |
| Ribokinase-like | 0 | DIRECT |
| Cysteine-rich domain | 0 | DIRECT |
| PAP/OAS1 substrate-binding domain | 0 | DIRECT |
| Immunoglobulin | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Poly A polymerase C-terminal region-like | 0 | DIRECT |
| GHMP Kinase, C-terminal domain | 0 | DIRECT |
| EF-hand | 0 | DIRECT |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
| 4'-phosphopantetheinyl transferase | 0 | DIRECT |
| GAF domain-like | 0 | DIRECT |
| RPB5-like RNA polymerase subunit | 0 | DIRECT |
| Sporulation response regulatory protein Spo0B | 0 | DIRECT |
| Guanido kinase N-terminal domain | 0 | DIRECT |
| G protein-binding domain | 0 | DIRECT |
| Sensory domain-like | 0 | DIRECT |
| YojJ-like | 0 | DIRECT |
| Nucleotidyltransferase | 0 | DIRECT |
| ApbE-like | 0 | DIRECT |
| BAR/IMD domain-like | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| CofD-like | 0 | DIRECT |
| Doublecortin (DC) | 0 | DIRECT |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
| RNI-like | 0 | DIRECT |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | DIRECT |
| Phosphohistidine domain | 0 | DIRECT |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
| DAK1/DegV-like | 0 | DIRECT |
| FAT domain of focal adhesion kinase | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| Carbamate kinase-like | 0 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
| Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
| Protein kinase-like (PK-like) | 0 | DIRECT |
| YgbK-like | 0 | DIRECT |
| Poly(A) polymerase catalytic subunit-like | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | DIRECT |
| Phoshotransferase/anion transport protein | 0 | DIRECT |
| MAST3 pre-PK domain-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| DhaL-like | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| DBL homology domain (DH-domain) | 0 | DIRECT |
| Actin-like ATPase domain | 0 | DIRECT |
| Glucose permease domain IIB | 0 | DIRECT |
| Trm112p-like | 0 | DIRECT |
| RNA polymerase subunit RPB10 | 0 | DIRECT |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
| CheY-binding domain of CheA | 0 | DIRECT |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
| Cadherin-like | 0 | DIRECT |
| Riboflavin kinase-like | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Phospholipase D/nuclease | 0 | DIRECT |
| C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| PUA domain-like | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
| Retroviral matrix proteins | 0 | DIRECT |
| SH3-domain | 0 | DIRECT |
| Nucleotidylyl transferase | 0 | DIRECT |
| Insert subdomain of RNA polymerase alpha subunit | 0 | DIRECT |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| TAF(II)230 TBP-binding fragment | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| Phosphoglycerate kinase | 0 | DIRECT |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
| Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
| RPB6/omega subunit-like | 0 | DIRECT |
| PsbU/PolX domain-like | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Glycerate kinase I | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| PK beta-barrel domain-like | 0 | DIRECT |
| Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 0 | DIRECT |
| Polo-box domain | 0 | DIRECT |
| PHP domain-like | 0 | DIRECT |
| HPr-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| Trypsin-like serine proteases | 0 | DIRECT |
| HAMP domain-like | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| L domain-like | 0 | DIRECT |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | DIRECT |
| Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
| CheW-like | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| PK C-terminal domain-like | 0 | DIRECT |
| PTS system IIB component-like | 0 | DIRECT |
| Notch domain | 0 | DIRECT |
| PPK N-terminal domain-like | 0 | DIRECT |
| PTS IIb component | 0 | DIRECT |
| Trimeric LpxA-like enzymes | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| Fibronectin type III | 0 | DIRECT |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| post-AAA+ oligomerization domain-like | 0.000000000000008377 | DIRECT |
| CheY-like | 0.000000000001382 | DIRECT |
| ARM repeat | 0.00000000000471 | DIRECT |
| Replicase NSP9 | 0.000000000007432 | DIRECT |
| Coronavirus NSP8-like | 0.000000000007432 | DIRECT |
| Coronavirus NSP10-like | 0.000000000007432 | DIRECT |
| Coronavirus NSP7-like | 0.000000000007432 | DIRECT |
| Ubiquitin-like | 0.0000000001213 | DIRECT |
| RNA polymerase subunits | 0.0000000001363 | DIRECT |
| Duplicated hybrid motif | 0.0000000002637 | DIRECT |
| GckA/TtuD-like | 0.000000001859 | DIRECT |
| HD-domain/PDEase-like | 0.00000000641 | DIRECT |
| NSP3A-like | 0.00000004121 | DIRECT |
| PX domain | 0.00000004139 | DIRECT |
| Hedgehog/intein (Hint) domain | 0.0000005197 | DIRECT |
| Quinoprotein alcohol dehydrogenase-like | 0.000003299 | DIRECT |
| GroEL apical domain-like | 0.000005282 | DIRECT |
| Second domain of FERM | 0.000009219 | DIRECT |
| CRAL/TRIO domain | 0.00001049 | DIRECT |
| YWTD domain | 0.00001441 | DIRECT |
| beta-sandwich domain of Sec23/24 | 0.00002911 | DIRECT |
| Glutamine synthetase/guanido kinase | 0.00005488 | DIRECT |
| DEATH domain | 0.00009068 | DIRECT |
| IpsF-like | 0.0001137 | DIRECT |
| NTF2-like | 0.0001439 | DIRECT |
| Homing endonucleases | 0.0002374 | DIRECT |
| MIT domain | 0.000561 | DIRECT |
| SARS Nsp1-like | 0.003282 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases |
| Myosin rod fragments | 0.004669 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| HIT-like | 0.005772 | INHERITED FROM: UDP-glucose--hexose-1-phosphate uridylyltransferase || Nucleotidyltransferases || Sulfate adenylyltransferase (ADP) || ATP adenylyltransferase |
| GTPase activation domain, GAP | 0.006413 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Chaperone J-domain | 0.006742 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| TPR-like | 0.007829 | INHERITED FROM: Dual-specificity kinases (those acting on Ser/Thr and Tyr residues) || Protein-serine/threonine kinases || Protein adenylyltransferase || Dual-specificity kinase || Non-specific serine/threonine protein kinase |
| Molybdenum cofactor biosynthesis proteins | 0.009034 | INHERITED FROM: Molybdopterin adenylyltransferase || Nucleotidyltransferases || FAD synthase |
| PDZ domain-like | 0.0092 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Nucleic acid-binding proteins | 0.01153 | INHERITED FROM: mRNA guanylyltransferase || Nucleotidyltransferases || Polyribonucleotide nucleotidyltransferase |
| C-terminal domain of transcriptional repressors | 0.02407 | INHERITED FROM: Pantothenate kinase || Phosphotransferases with an alcohol group as acceptor |
| Rubredoxin-like | 0.02625 | INHERITED FROM: Adenylate kinase || Phosphotransferases with a phosphate group as acceptor |
| GroEL-intermediate domain like | 0.03807 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || 1-phosphatidylinositol-3-phosphate 5-kinase |
| HCP-like | 0.03813 | INHERITED FROM: Protein-serine/threonine kinases || [Elongation factor 2] kinase |
| cAMP-binding domain-like | 0.04852 | INHERITED FROM: cGMP-dependent protein kinase || Protein-serine/threonine kinases |
| RCC1/BLIP-II | 0.05358 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| C-type lectin-like | 0.05934 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| CYTH-like phosphatases | 0.08976 | INHERITED FROM: mRNA guanylyltransferase |
| Nucleotide cyclase | 0.09331 | INHERITED FROM: Nucleotidyltransferases || Diguanylate cyclase |
| SMAD/FHA domain | 0.1148 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| WD40 repeat-like | 0.2551 | INHERITED FROM: [Myosin heavy-chain] kinase || Protein-serine/threonine kinases |
| Macro domain-like | 0.3191 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases || Polynucleotide adenylyltransferase |
| SAICAR synthase-like | 0.4904 | INHERITED FROM: Inositol-hexakisphosphate kinase || 1-phosphatidylinositol-4-phosphate 5-kinase || Inositol-polyphosphate multikinase || Phosphotransferases with an alcohol group as acceptor || Inositol-tetrakisphosphate 5-kinase || Phosphatidylinositol-4,5-bisphosphate 3-kinase || 1-phosphatidylinositol-3-phosphate 5-kinase || 1-phosphatidylinositol-5-phosphate 4-kinase || Inositol-trisphosphate 3-kinase |
| Cyclin-like | 0.5537 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Homeodomain-like | 0.65 | INHERITED FROM: Glucokinase || Phosphotransferases with an alcohol group as acceptor |
| MoeA N-terminal region -like | 0.6919 | INHERITED FROM: Molybdopterin adenylyltransferase || Nucleotidyltransferases |
| MoeA C-terminal domain-like | 0.6919 | INHERITED FROM: Molybdopterin adenylyltransferase || Nucleotidyltransferases |
| Zinc beta-ribbon | 0.7077 | INHERITED FROM: DNA-directed RNA polymerase |
| UBA-like | 0.7143 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| PurM N-terminal domain-like | 0.7212 | INHERITED FROM: Phosphotransferases with paired acceptors || Thiamine-phosphate kinase || Selenide, water dikinase |
| Globin-like | 0.7244 | INHERITED FROM: Diguanylate cyclase |
| PurM C-terminal domain-like | 0.7267 | INHERITED FROM: Phosphotransferases with paired acceptors || Thiamine-phosphate kinase || Selenide, water dikinase |
| Galactose oxidase, central domain | 0.7517 | INHERITED FROM: Phosphotransferases with a phosphate group as acceptor || Guanylate kinase |
| Ribonuclease Rh-like | 0.8127 | INHERITED FROM: RNA-directed RNA polymerase |
| Kringle-like | 0.9057 | INHERITED FROM: Protein-tyrosine kinases || Receptor protein-tyrosine kinase |
| Sec63 N-terminal domain-like | 0.9937 | INHERITED FROM: DNA-directed DNA polymerase |
| RNA-binding domain, RBD | 0.9998 | INHERITED FROM: RNA uridylyltransferase || Polynucleotide adenylyltransferase |
| Galactose-binding domain-like | 1 | INHERITED FROM: Protein-tyrosine kinases || Receptor protein-tyrosine kinase |
| BRCT domain | 1 | INHERITED FROM: DNA nucleotidylexotransferase |
| Adenine nucleotide alpha hydrolases-like | 1 | INHERITED FROM: Sulfate adenylyltransferase || FAD synthase |
| UDP-Glycosyltransferase/glycogen phosphorylase | 1 | INHERITED FROM: Teichoic acid glycerol-phosphate primase || Teichoic acid poly(glycerol phosphate) polymerase || N-acylmannosamine kinase |
| "Winged helix" DNA-binding domain | 1 | INHERITED FROM: CTP-dependent riboflavin kinase || 1-phosphatidylinositol-3-phosphate 5-kinase |
| Phosphoenolpyruvate/pyruvate domain | 1 | INHERITED FROM: Phosphotransferases with paired acceptors || Pyruvate, phosphate dikinase || Pyruvate kinase || Phosphotransferases with an alcohol group as acceptor || Phosphotransferases with a nitrogenous group as acceptor || Protein-N(pi)-phosphohistidine--D-fructose phosphotransferase || Phosphoenolpyruvate--protein phosphotransferase || Pyruvate, water dikinase |
| RmlC-like cupins | 1 | INHERITED FROM: Mannose-1-phosphate guanylyltransferase |
| Dehydroquinate synthase-like | 1 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || Shikimate kinase |
| (Phosphotyrosine protein) phosphatases II | 1 | INHERITED FROM: mRNA guanylyltransferase |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | INHERITED FROM: 6-phosphofructokinase |
| Thioredoxin-like | 1 | INHERITED FROM: Protein-histidine kinases |
| Heme oxygenase-like | 1 | INHERITED FROM: Hydroxymethylpyrimidine kinase || Phosphooxymethylpyrimidine kinase |
| Aldolase | 1 | INHERITED FROM: Shikimate kinase |
| Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: Inositol-hexakisphosphate kinase || Phosphotransferases with paired acceptors || Pyruvate, phosphate dikinase || Inositol-1,3,4-trisphosphate 5/6-kinase || Inositol-tetrakisphosphate 1-kinase || Diphosphoinositol-pentakisphosphate kinase || Pyruvate, water dikinase |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
| E set domains | 1 | INHERITED FROM: RNA-directed RNA polymerase || Protein-tyrosine kinases || Receptor protein-tyrosine kinase || Nucleotidyltransferases |
| SGNH hydrolase | 1 | INHERITED FROM: N-acylneuraminate cytidylyltransferase |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
| TGS-like | 1 | INHERITED FROM: GTP diphosphokinase || Diphosphotransferases |
| Phosphoglycerate mutase-like | 1 | INHERITED FROM: Inositol-hexakisphosphate kinase || Diphosphoinositol-pentakisphosphate kinase || 6-phosphofructo-2-kinase |
| Concanavalin A-like lectins/glucanases | 1 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| DNase I-like | 1 | INHERITED FROM: RNA-directed DNA polymerase |
| lambda repressor-like DNA-binding domains | 1 | INHERITED FROM: Ribosylnicotinamide kinase || Nicotinamide-nucleotide adenylyltransferase |
| FYVE/PHD zinc finger | 1 | INHERITED FROM: Protein-tyrosine kinases || 1-phosphatidylinositol-3-phosphate 5-kinase || Non-specific protein-tyrosine kinase |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: mRNA guanylyltransferase |
| ADP-ribosylation | 1 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || 2'-phosphotransferase || 1-phosphatidylinositol 4-kinase |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Shikimate kinase || Aspartate kinase |
| SIS domain | 1 | INHERITED FROM: Glucokinase |
| Nudix | 1 | INHERITED FROM: ADP-D-ribose pyrophosphorylase |
| Thiamin phosphate synthase | 1 | INHERITED FROM: Hydroxymethylpyrimidine kinase || Phosphooxymethylpyrimidine kinase |
| EPT/RTPC-like | 1 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || Shikimate kinase |
| Clavaminate synthase-like | 1 | INHERITED FROM: RNA-directed RNA polymerase |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
| Dihydropteroate synthetase-like | 1 | INHERITED FROM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase || Diphosphotransferases |
| PRTase-like | 1 | INHERITED FROM: Uridine kinase || Ribose-phosphate diphosphokinase || Diphosphotransferases |
| Cysteine proteinases | 1 | INHERITED FROM: RNA-directed RNA polymerase |
| Ankyrin repeat | 1 | INHERITED FROM: Diacylglycerol kinase (ATP) || Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
| Translation proteins | 1 | INHERITED FROM: Sulfate adenylyltransferase || Nucleotidyltransferases || Adenylyl-sulfate kinase |
| beta-beta-alpha zinc fingers | 1 | INHERITED FROM: RNA uridylyltransferase || Polynucleotide adenylyltransferase |
| Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| HAD-like | 1 | INHERITED FROM: Polynucleotide 5'-hydroxyl-kinase || N-acylneuraminate cytidylyltransferase |
| Bromodomain | 1 | INHERITED FROM: Protein-tyrosine kinases || Non-specific serine/threonine protein kinase || Non-specific protein-tyrosine kinase |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
| dUTPase-like | 1 | INHERITED FROM: RNA-directed DNA polymerase || DNA-directed DNA polymerase |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | INHERITED FROM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase || Diphosphotransferases |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | INHERITED FROM: RNA-directed RNA polymerase || mRNA guanylyltransferase |
| ALDH-like | 1 | INHERITED FROM: Glutamate 5-kinase |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Transferases for other substituted phosphate groups || Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase |
| Phosphoglucomutase, C-terminal domain | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Shikimate kinase |
| RuvA domain 2-like | 1 | INHERITED FROM: Diadenylate cyclase |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
| Tricorn protease domain 2 | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| Phosphofructokinase | 0 | Direct |
| Thiamin pyrophosphokinase, catalytic domain | 0 | Direct |
| 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
| Retrovirus capsid dimerization domain-like | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| SH2 domain | 0 | Direct |
| Ribonuclease H-like | 0 | Direct |
| DNA polymerase III chi subunit | 0 | Direct |
| PTS system fructose IIA component-like | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| NAD kinase/diacylglycerol kinase-like | 0 | Direct |
| Growth factor receptor domain | 0 | Direct |
| AF1531-like | 0 | Direct |
| YrdC/RibB | 0 | Direct |
| Fic-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| PHP14-like | 0 | Direct |
| SAM/Pointed domain | 0 | Direct |
| alpha-D-mannose-specific plant lectins | 0 | Direct |
| Ribokinase-like | 0 | Direct |
| Cysteine-rich domain | 0 | Direct |
| PAP/OAS1 substrate-binding domain | 0 | Direct |
| Immunoglobulin | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Poly A polymerase C-terminal region-like | 0 | Direct |
| GHMP Kinase, C-terminal domain | 0 | Direct |
| EF-hand | 0 | Direct |
| Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
| 4'-phosphopantetheinyl transferase | 0 | Direct |
| GAF domain-like | 0 | Direct |
| RPB5-like RNA polymerase subunit | 0 | Direct |
| Sporulation response regulatory protein Spo0B | 0 | Direct |
| Guanido kinase N-terminal domain | 0 | Direct |
| G protein-binding domain | 0 | Direct |
| Sensory domain-like | 0 | Direct |
| YojJ-like | 0 | Direct |
| Nucleotidyltransferase | 0 | Direct |
| ApbE-like | 0 | Direct |
| BAR/IMD domain-like | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| CofD-like | 0 | Direct |
| Doublecortin (DC) | 0 | Direct |
| Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
| RNI-like | 0 | Direct |
| Nucleotidyltransferase substrate binding subunit/domain | 0 | Direct |
| Phosphohistidine domain | 0 | Direct |
| Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
| DAK1/DegV-like | 0 | Direct |
| FAT domain of focal adhesion kinase | 0 | Direct |
| Acid proteases | 0 | Direct |
| Carbamate kinase-like | 0 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
| Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
| Protein kinase-like (PK-like) | 0 | Direct |
| YgbK-like | 0 | Direct |
| Poly(A) polymerase catalytic subunit-like | 0 | Direct |
| KA1-like | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| PIN domain-like | 0 | Direct |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| N-terminal, heterodimerisation domain of RBP7 (RpoE) | 0 | Direct |
| Phoshotransferase/anion transport protein | 0 | Direct |
| MAST3 pre-PK domain-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| DhaL-like | 0 | Direct |
| EndoU-like | 0 | Direct |
| DBL homology domain (DH-domain) | 0 | Direct |
| Actin-like ATPase domain | 0 | Direct |
| Glucose permease domain IIB | 0 | Direct |
| Trm112p-like | 0 | Direct |
| RNA polymerase subunit RPB10 | 0 | Direct |
| Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
| CheY-binding domain of CheA | 0 | Direct |
| EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
| Cadherin-like | 0 | Direct |
| Riboflavin kinase-like | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Phospholipase D/nuclease | 0 | Direct |
| C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| PUA domain-like | 0 | Direct |
| PH domain-like | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| DNA polymerase beta, N-terminal domain-like | 0 | Direct |
| Retroviral matrix proteins | 0 | Direct |
| SH3-domain | 0 | Direct |
| Nucleotidylyl transferase | 0 | Direct |
| Insert subdomain of RNA polymerase alpha subunit | 0 | Direct |
| Histidine-containing phosphotransfer domain, HPT domain | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| TAF(II)230 TBP-binding fragment | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| Phosphoglycerate kinase | 0 | Direct |
| Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
| Nucleotide-diphospho-sugar transferases | 0 | Direct |
| RPB6/omega subunit-like | 0 | Direct |
| PsbU/PolX domain-like | 0 | Direct |
| Sema domain | 0 | Direct |
| Glycerate kinase I | 0 | Direct |
| L27 domain | 0 | Direct |
| PK beta-barrel domain-like | 0 | Direct |
| Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 0 | Direct |
| Polo-box domain | 0 | Direct |
| PHP domain-like | 0 | Direct |
| HPr-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| Trypsin-like serine proteases | 0 | Direct |
| HAMP domain-like | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| L domain-like | 0 | Direct |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
| alpha-ketoacid dehydrogenase kinase, N-terminal domain | 0 | Direct |
| Nucleoside diphosphate kinase, NDK | 0 | Direct |
| CheW-like | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| PK C-terminal domain-like | 0 | Direct |
| PTS system IIB component-like | 0 | Direct |
| Notch domain | 0 | Direct |
| PPK N-terminal domain-like | 0 | Direct |
| PTS IIb component | 0 | Direct |
| Trimeric LpxA-like enzymes | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| Fibronectin type III | 0 | Direct |
| FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 0 | Direct |
| ACT-like | 0 | Direct |
| post-AAA+ oligomerization domain-like | 0.000000000000008377 | Direct |
| CheY-like | 0.000000000001382 | Direct |
| ARM repeat | 0.00000000000471 | Direct |
| Replicase NSP9 | 0.000000000007432 | Direct |
| Coronavirus NSP8-like | 0.000000000007432 | Direct |
| Coronavirus NSP10-like | 0.000000000007432 | Direct |
| Coronavirus NSP7-like | 0.000000000007432 | Direct |
| Ubiquitin-like | 0.0000000001213 | Direct |
| RNA polymerase subunits | 0.0000000001363 | Direct |
| Duplicated hybrid motif | 0.0000000002637 | Direct |
| GckA/TtuD-like | 0.000000001859 | Direct |
| HD-domain/PDEase-like | 0.00000000641 | Direct |
| NSP3A-like | 0.00000004121 | Direct |
| PX domain | 0.00000004139 | Direct |
| Hedgehog/intein (Hint) domain | 0.0000005197 | Direct |
| Quinoprotein alcohol dehydrogenase-like | 0.000003299 | Direct |
| GroEL apical domain-like | 0.000005282 | Direct |
| Second domain of FERM | 0.000009219 | Direct |
| CRAL/TRIO domain | 0.00001049 | Direct |
| YWTD domain | 0.00001441 | Direct |
| beta-sandwich domain of Sec23/24 | 0.00002911 | Direct |
| Glutamine synthetase/guanido kinase | 0.00005488 | Direct |
| DEATH domain | 0.00009068 | Direct |
| IpsF-like | 0.0001137 | Direct |
| NTF2-like | 0.0001439 | Direct |
| Homing endonucleases | 0.0002374 | Direct |
| MIT domain | 0.000561 | Direct |
| SARS Nsp1-like | 0.003282 | Inherited |
| Myosin rod fragments | 0.004669 | Inherited |
| HIT-like | 0.005772 | Inherited |
| GTPase activation domain, GAP | 0.006413 | Inherited |
| Chaperone J-domain | 0.006742 | Inherited |
| TPR-like | 0.007829 | Inherited |
| Molybdenum cofactor biosynthesis proteins | 0.009034 | Inherited |
| PDZ domain-like | 0.0092 | Inherited |
| Nucleic acid-binding proteins | 0.01153 | Inherited |
| C-terminal domain of transcriptional repressors | 0.02407 | Inherited |
| Rubredoxin-like | 0.02625 | Inherited |
| GroEL-intermediate domain like | 0.03807 | Inherited |
| HCP-like | 0.03813 | Inherited |
| cAMP-binding domain-like | 0.04852 | Inherited |
| RCC1/BLIP-II | 0.05358 | Inherited |
| C-type lectin-like | 0.05934 | Inherited |
| CYTH-like phosphatases | 0.08976 | Inherited |
| Nucleotide cyclase | 0.09331 | Inherited |
| SMAD/FHA domain | 0.1148 | Inherited |
| WD40 repeat-like | 0.2551 | Inherited |
| Macro domain-like | 0.3191 | Inherited |
| SAICAR synthase-like | 0.4904 | Inherited |
| Cyclin-like | 0.5537 | Inherited |
| Homeodomain-like | 0.65 | Inherited |
| MoeA N-terminal region -like | 0.6919 | Inherited |
| MoeA C-terminal domain-like | 0.6919 | Inherited |
| Zinc beta-ribbon | 0.7077 | Inherited |
| UBA-like | 0.7143 | Inherited |
| PurM N-terminal domain-like | 0.7212 | Inherited |
| Globin-like | 0.7244 | Inherited |
| PurM C-terminal domain-like | 0.7267 | Inherited |
| Galactose oxidase, central domain | 0.7517 | Inherited |
| Ribonuclease Rh-like | 0.8127 | Inherited |
| Kringle-like | 0.9057 | Inherited |
| Sec63 N-terminal domain-like | 0.9937 | Inherited |
| RNA-binding domain, RBD | 0.9998 | Inherited |
| Galactose-binding domain-like | 1 | Inherited |
| BRCT domain | 1 | Inherited |
| Adenine nucleotide alpha hydrolases-like | 1 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 1 | Inherited |
| "Winged helix" DNA-binding domain | 1 | Inherited |
| Phosphoenolpyruvate/pyruvate domain | 1 | Inherited |
| RmlC-like cupins | 1 | Inherited |
| Dehydroquinate synthase-like | 1 | Inherited |
| (Phosphotyrosine protein) phosphatases II | 1 | Inherited |
| Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | Inherited |
| Thioredoxin-like | 1 | Inherited |
| Heme oxygenase-like | 1 | Inherited |
| Aldolase | 1 | Inherited |
| Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
| Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 1 | Inherited |
| E set domains | 1 | Inherited |
| SGNH hydrolase | 1 | Inherited |
| Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 1 | Inherited |
| TGS-like | 1 | Inherited |
| Phosphoglycerate mutase-like | 1 | Inherited |
| Concanavalin A-like lectins/glucanases | 1 | Inherited |
| DNase I-like | 1 | Inherited |
| lambda repressor-like DNA-binding domains | 1 | Inherited |
| FYVE/PHD zinc finger | 1 | Inherited |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
| ADP-ribosylation | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| SIS domain | 1 | Inherited |
| Nudix | 1 | Inherited |
| Thiamin phosphate synthase | 1 | Inherited |
| EPT/RTPC-like | 1 | Inherited |
| Clavaminate synthase-like | 1 | Inherited |
| Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | Inherited |
| Dihydropteroate synthetase-like | 1 | Inherited |
| PRTase-like | 1 | Inherited |
| Cysteine proteinases | 1 | Inherited |
| Ankyrin repeat | 1 | Inherited |
| Translation proteins | 1 | Inherited |
| beta-beta-alpha zinc fingers | 1 | Inherited |
| Phosphoglucomutase, first 3 domains | 1 | Inherited |
| HAD-like | 1 | Inherited |
| Bromodomain | 1 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | Inherited |
| dUTPase-like | 1 | Inherited |
| Tetrahydrobiopterin biosynthesis enzymes-like | 1 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | Inherited |
| ALDH-like | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| Phosphoglucomutase, C-terminal domain | 1 | Inherited |
| Aminoacid dehydrogenase-like, N-terminal domain | 1 | Inherited |
| RuvA domain 2-like | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (SPEC level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56112,101288
56112 - Protein kinase-like (PK-like)
101288 - L27 domain | 0 | DIRECT |
55604,51261
55604 - Glucose permease domain IIB
51261 - Duplicated hybrid motif | 0 | DIRECT |
53850,56112
53850 - Periplasmic binding protein-like II
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55021,56112
55021 - ACT-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53448,51161
53448 - Nucleotide-diphospho-sugar transferases
51161 - Trimeric LpxA-like enzymes | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | DIRECT |
56112,54427
56112 - Protein kinase-like (PK-like)
54427 - NTF2-like | 0 | DIRECT |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
81301,81891
81301 - Nucleotidyltransferase
81891 - Poly A polymerase C-terminal region-like | 0 | DIRECT |
103190,47384
103190 - Sensory domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
52374,52540
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,51569
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | DIRECT |
109604,81301
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase | 0 | DIRECT |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,47473
56112 - Protein kinase-like (PK-like)
47473 - EF-hand | 0 | DIRECT |
52374,82114
52374 - Nucleotidylyl transferase
82114 - Riboflavin kinase-like | 0 | DIRECT |
52540,47648
52540 - P-loop containing nucleoside triphosphate hydrolases
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | DIRECT |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | DIRECT |
55608,56672
55608 - Homing endonucleases
56672 - DNA/RNA polymerases | 0 | DIRECT |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | DIRECT |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
81593,81891
81593 - Nucleotidyltransferase substrate binding subunit/domain
81891 - Poly A polymerase C-terminal region-like | 0 | DIRECT |
88697,52374
88697 - PUA domain-like
52374 - Nucleotidylyl transferase | 0 | DIRECT |
56112,52799
56112 - Protein kinase-like (PK-like)
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
56112,50998
56112 - Protein kinase-like (PK-like)
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
55666,46915
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
56219,56672
56219 - DNase I-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
50800,51621
50800 - PK beta-barrel domain-like
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
56784,52540
56784 - HAD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47807,53098
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like | 0 | DIRECT |
158472,55785
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
55083,51717
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
51717 - Dihydropteroate synthetase-like | 0 | DIRECT |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
52172,55785
52172 - CheY-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
52949,52540
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
64484,-9
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
-9 - PDB | 0 | DIRECT |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
47212,56112
47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55781,47384
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
48452,140931
48452 - TPR-like
140931 - Fic-like | 0 | DIRECT |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0 | DIRECT |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | DIRECT |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
55205,52540
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56112,52540
56112 - Protein kinase-like (PK-like)
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | DIRECT |
50037,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | DIRECT |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
53098,53098
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | DIRECT |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | DIRECT |
56112,50044
56112 - Protein kinase-like (PK-like)
50044 - SH3-domain | 0 | DIRECT |
52799,56091
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
55804,52794
55804 - Phoshotransferase/anion transport protein
52794 - PTS system IIB component-like | 0 | DIRECT |
47986,56112
47986 - DEATH domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,48403
56112 - Protein kinase-like (PK-like)
48403 - Ankyrin repeat | 0 | DIRECT |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
56112,50978
56112 - Protein kinase-like (PK-like)
50978 - WD40 repeat-like | 0 | DIRECT |
158472,47384
158472 - HAMP domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
47836,47943
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
55890,55874
55890 - Sporulation response regulatory protein Spo0B
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
64484,64484
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
53613,52374
53613 - Ribokinase-like
52374 - Nucleotidylyl transferase | 0 | DIRECT |
54277,56112
54277 - CAD & PB1 domains
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | DIRECT |
109604,55021
109604 - HD-domain/PDEase-like
55021 - ACT-like | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
88798,50249
88798 - N-terminal, heterodimerisation domain of RBP7 (RpoE)
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
52540,53271
52540 - P-loop containing nucleoside triphosphate hydrolases
53271 - PRTase-like | 0 | DIRECT |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | DIRECT |
50249,89550
50249 - Nucleic acid-binding proteins
89550 - PHP domain-like | 0 | DIRECT |
46689,53697
46689 - Homeodomain-like
53697 - SIS domain | 0 | DIRECT |
52047,56112
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
51621,52935
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like | 0 | DIRECT |
54197,54197
54197 - HIT-like
54197 - HIT-like | 0 | DIRECT |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54277,57889
54277 - CAD & PB1 domains
57889 - Cysteine-rich domain | 0 | DIRECT |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55874,52172
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like | 0 | DIRECT |
50249,56300
50249 - Nucleic acid-binding proteins
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
56672,90234
56672 - DNA/RNA polymerases
90234 - Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
55073,56112
55073 - Nucleotide cyclase
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53850,55785
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
56112,116846
56112 - Protein kinase-like (PK-like)
116846 - MIT domain | 0 | DIRECT |
55781,55874
55781 - GAF domain-like
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
52172,47226
52172 - CheY-like
47226 - Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
56672,46919
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | DIRECT |
47226,55052
47226 - Histidine-containing phosphotransfer domain, HPT domain
55052 - CheY-binding domain of CheA | 0 | DIRECT |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
56112,48452
56112 - Protein kinase-like (PK-like)
48452 - TPR-like | 0 | DIRECT |
52540,52402
52540 - P-loop containing nucleoside triphosphate hydrolases
52402 - Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | DIRECT |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | DIRECT |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | DIRECT |
88723,47807
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain | 0 | DIRECT |
53448,69765
53448 - Nucleotide-diphospho-sugar transferases
69765 - IpsF-like | 0 | DIRECT |
51110,51110
51110 - alpha-D-mannose-specific plant lectins
51110 - alpha-D-mannose-specific plant lectins | 0 | DIRECT |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
56796,55205
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like | 0 | DIRECT |
51621,55804
51621 - Phosphoenolpyruvate/pyruvate domain
55804 - Phoshotransferase/anion transport protein | 0 | DIRECT |
51391,53613
51391 - Thiamin phosphate synthase
53613 - Ribokinase-like | 0 | DIRECT |
55594,47831
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
49562,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55931,48034
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain | 0 | DIRECT |
50729,69322
50729 - PH domain-like
69322 - Tricorn protease domain 2 | 0 | DIRECT |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | DIRECT |
57440,56112
57440 - Kringle-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57774,52540
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
52833,47384
52833 - Thioredoxin-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
55785,55781
55785 - PYP-like sensor domain (PAS domain)
55781 - GAF domain-like | 0 | DIRECT |
54791,50249
54791 - Eukaryotic type KH-domain (KH-domain type I)
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | DIRECT |
56214,56214
56214 - 4'-phosphopantetheinyl transferase
56214 - 4'-phosphopantetheinyl transferase | 0 | DIRECT |
101288,101288
101288 - L27 domain
101288 - L27 domain | 0 | DIRECT |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | DIRECT |
46585,49562
46585 - HR1 repeat
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
63999,63862
63999 - Thiamin pyrophosphokinase, catalytic domain
63862 - Thiamin pyrophosphokinase, substrate-binding domain | 0 | DIRECT |
55785,55890
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B | 0 | DIRECT |
47802,81585
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like | 0 | DIRECT |
103190,158472
103190 - Sensory domain-like
158472 - HAMP domain-like | 0 | DIRECT |
53633,53720
53633 - Carbamate kinase-like
53720 - ALDH-like | 0 | DIRECT |
55785,47384
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
81301,47473
81301 - Nucleotidyltransferase
47473 - EF-hand | 0 | DIRECT |
57716,50156
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like | 0 | DIRECT |
81301,81593
81301 - Nucleotidyltransferase
81593 - Nucleotidyltransferase substrate binding subunit/domain | 0 | DIRECT |
-9,-7
-9 - PDB
-7 - CATH | 0 | DIRECT |
81631,81301
81631 - PAP/OAS1 substrate-binding domain
81301 - Nucleotidyltransferase | 0 | DIRECT |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
52540,57802
52540 - P-loop containing nucleoside triphosphate hydrolases
57802 - Rubredoxin-like | 0 | DIRECT |
52794,52794
52794 - PTS system IIB component-like
52794 - PTS system IIB component-like | 0 | DIRECT |
56112,50985
56112 - Protein kinase-like (PK-like)
50985 - RCC1/BLIP-II | 0 | DIRECT |
56112,64268
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | DIRECT |
53271,53271
53271 - PRTase-like
53271 - PRTase-like | 0 | DIRECT |
53067,56112
53067 - Actin-like ATPase domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
53756,53067
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53067 - Actin-like ATPase domain | 0 | DIRECT |
46785,56112
46785 - "Winged helix" DNA-binding domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,90257
56112 - Protein kinase-like (PK-like)
90257 - Myosin rod fragments | 0 | DIRECT |
46785,82114
46785 - "Winged helix" DNA-binding domain
82114 - Riboflavin kinase-like | 0 | DIRECT |
143724,56024
143724 - PHP14-like
56024 - Phospholipase D/nuclease | 0 | DIRECT |
53062,55594
53062 - PTS system fructose IIA component-like
55594 - HPr-like | 0 | DIRECT |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
52009,51621
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
64268,49562
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
55154,56091
55154 - CYTH-like phosphatases
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | DIRECT |
56672,55608
56672 - DNA/RNA polymerases
55608 - Homing endonucleases | 0 | DIRECT |
50998,56112
50998 - Quinoprotein alcohol dehydrogenase-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54919,54919
54919 - Nucleoside diphosphate kinase, NDK
54919 - Nucleoside diphosphate kinase, NDK | 0 | DIRECT |
50965,52540
50965 - Galactose oxidase, central domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
116846,116846
116846 - MIT domain
116846 - MIT domain | 0 | DIRECT |
49899,56112
49899 - Concanavalin A-like lectins/glucanases
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50156,56112
50156 - PDZ domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56672,51294
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
56112,54928
56112 - Protein kinase-like (PK-like)
54928 - RNA-binding domain, RBD | 0 | DIRECT |
52087,46966
52087 - CRAL/TRIO domain
46966 - Spectrin repeat | 0 | DIRECT |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | DIRECT |
82549,101473
82549 - DAK1/DegV-like
101473 - DhaL-like | 0 | DIRECT |
140356,143724
140356 - PPK N-terminal domain-like
143724 - PHP14-like | 0 | DIRECT |
49562,48350
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | DIRECT |
53448,51182
53448 - Nucleotide-diphospho-sugar transferases
51182 - RmlC-like cupins | 0 | DIRECT |
51294,56672
51294 - Hedgehog/intein (Hint) domain
56672 - DNA/RNA polymerases | 0 | DIRECT |
52794,55804
52794 - PTS system IIB component-like
55804 - Phoshotransferase/anion transport protein | 0 | DIRECT |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | DIRECT |
81585,81301
81585 - PsbU/PolX domain-like
81301 - Nucleotidyltransferase | 0 | DIRECT |
81995,56112
81995 - beta-sandwich domain of Sec23/24
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | DIRECT |
50465,52540
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
55257,47789
55257 - RBP11-like subunits of RNA polymerase
47789 - C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
52058,56112
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55666,54791
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
57889,111331
57889 - Cysteine-rich domain
111331 - NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
54236,56112
54236 - Ubiquitin-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53633,55021
53633 - Carbamate kinase-like
55021 - ACT-like | 0 | DIRECT |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | DIRECT |
55874,50341
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
50341 - CheW-like | 0 | DIRECT |
53448,52266
53448 - Nucleotide-diphospho-sugar transferases
52266 - SGNH hydrolase | 0 | DIRECT |
56553,55257
56553 - Insert subdomain of RNA polymerase alpha subunit
55257 - RBP11-like subunits of RNA polymerase | 0 | DIRECT |
55620,55083
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49265,63825
49265 - Fibronectin type III
63825 - YWTD domain | 0 | DIRECT |
51735,52540
51735 - NAD(P)-binding Rossmann-fold domains
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
56112,103243
56112 - Protein kinase-like (PK-like)
103243 - KA1-like | 0 | DIRECT |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
51569,53223
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
47807,56672
47807 - 5' to 3' exonuclease, C-terminal subdomain
56672 - DNA/RNA polymerases | 0 | DIRECT |
53448,56784
53448 - Nucleotide-diphospho-sugar transferases
56784 - HAD-like | 0 | DIRECT |
89550,53098
89550 - PHP domain-like
53098 - Ribonuclease H-like | 0 | DIRECT |
52540,57774
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
55021,51735
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,57716
52540 - P-loop containing nucleoside triphosphate hydrolases
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
55052,47384
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
55781,55785
55781 - GAF domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
63825,49265
63825 - YWTD domain
49265 - Fibronectin type III | 0 | DIRECT |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | DIRECT |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | DIRECT |
56112,48726
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin | 0 | DIRECT |
52540,88697
52540 - P-loop containing nucleoside triphosphate hydrolases
88697 - PUA domain-like | 0 | DIRECT |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | DIRECT |
53633,88697
53633 - Carbamate kinase-like
88697 - PUA domain-like | 0 | DIRECT |
103190,55785
103190 - Sensory domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
89837,89837
89837 - Doublecortin (DC)
89837 - Doublecortin (DC) | 0 | DIRECT |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
47831,52009
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain | 0 | DIRECT |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
64268,56112
64268 - PX domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52113,47802
52113 - BRCT domain
47802 - DNA polymerase beta, N-terminal domain-like | 0 | DIRECT |
81631,57756
81631 - PAP/OAS1 substrate-binding domain
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
46915,54211
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
52540,81301
52540 - P-loop containing nucleoside triphosphate hydrolases
81301 - Nucleotidyltransferase | 0 | DIRECT |
54593,53784
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
53784 - Phosphofructokinase | 0 | DIRECT |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | DIRECT |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57667,54928
57667 - beta-beta-alpha zinc fingers
54928 - RNA-binding domain, RBD | 0 | DIRECT |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | DIRECT |
52935,52009
52935 - PK C-terminal domain-like
52009 - Phosphohistidine domain | 0 | DIRECT |
55021,55021
55021 - ACT-like
55021 - ACT-like | 0 | DIRECT |
56112,55681
56112 - Protein kinase-like (PK-like)
55681 - Class II aaRS and biotin synthetases | 0 | DIRECT |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81891,109604
81891 - Poly A polymerase C-terminal region-like
109604 - HD-domain/PDEase-like | 0 | DIRECT |
47391,52540
47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47384,55874
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
56059,52009
56059 - Glutathione synthetase ATP-binding domain-like
52009 - Phosphohistidine domain | 0 | DIRECT |
53613,51391
53613 - Ribokinase-like
51391 - Thiamin phosphate synthase | 0 | DIRECT |
52172,52172
52172 - CheY-like
52172 - CheY-like | 0 | DIRECT |
52047,52058
52047 - RNI-like
52058 - L domain-like | 0 | DIRECT |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.000000000000001059 | DIRECT |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0.00000000000000246 | DIRECT |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0.000000000000007682 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0.000000000000008377 | DIRECT |
81301,81271
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.00000000000002681 | DIRECT |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0.00000000000008799 | DIRECT |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0.000000000007432 | DIRECT |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.000000000007432 | DIRECT |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.000000000007432 | DIRECT |
51206,56112
51206 - cAMP-binding domain-like
56112 - Protein kinase-like (PK-like) | 0.00000000002565 | DIRECT |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0.0000000000293 | DIRECT |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.0000000003026 | DIRECT |
52374,52374
52374 - Nucleotidylyl transferase
52374 - Nucleotidylyl transferase | 0.000001297 | DIRECT |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.000002456 | DIRECT |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.000006963 | DIRECT |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.000009738 | DIRECT |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0.00001049 | DIRECT |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.00001843 | DIRECT |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.00002935 | DIRECT |
57756,51283
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0.0000946 | DIRECT |
51283,50630
51283 - dUTPase-like
50630 - Acid proteases | 0.0000946 | DIRECT |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.0001575 | DIRECT |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0.0003032 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.0003791 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0.0005992 | DIRECT |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.0007132 | DIRECT |
55785,55073
55785 - PYP-like sensor domain (PAS domain)
55073 - Nucleotide cyclase | 0.002588 | INHERITED FROM: Nucleotidyltransferases || Diguanylate cyclase |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0.003282 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.006742 | INHERITED FROM: RNA-directed RNA polymerase || Nucleotidyltransferases |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.022 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0.02407 | INHERITED FROM: Protein-tyrosine kinases || Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase || Non-specific protein-tyrosine kinase |
55681,50037
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors | 0.02407 | INHERITED FROM: Pantothenate kinase || Phosphotransferases with an alcohol group as acceptor |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.03527 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.03807 | INHERITED FROM: Phosphotransferases with an alcohol group as acceptor || 1-phosphatidylinositol-3-phosphate 5-kinase |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0.05024 | INHERITED FROM: cGMP-dependent protein kinase || Protein-serine/threonine kinases |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.07724 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
-9,-9
-9 - PDB
-9 - PDB | 0.1061 | INHERITED FROM: DNA-directed RNA polymerase || Nucleotidyltransferases |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.1941 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 0.3075 | INHERITED FROM: Protein-histidine kinases |
48403,47769
48403 - Ankyrin repeat
47769 - SAM/Pointed domain | 0.3131 | INHERITED FROM: Protein-serine/threonine kinases || Non-specific serine/threonine protein kinase |
63882,53218
63882 - MoeA N-terminal region -like
53218 - Molybdenum cofactor biosynthesis proteins | 0.6919 | INHERITED FROM: Molybdopterin adenylyltransferase || Nucleotidyltransferases |
53218,63867
53218 - Molybdenum cofactor biosynthesis proteins
63867 - MoeA C-terminal domain-like | 0.6919 | INHERITED FROM: Molybdopterin adenylyltransferase || Nucleotidyltransferases |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0.7156 | INHERITED FROM: Phosphotransferases with paired acceptors || Thiamine-phosphate kinase || Selenide, water dikinase |
55620,55620
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55620 - Tetrahydrobiopterin biosynthesis enzymes-like | 0.8009 | INHERITED FROM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase || Diphosphotransferases |
81296,81296
81296 - E set domains
81296 - E set domains | 1 | INHERITED FROM: Protein-tyrosine kinases || Receptor protein-tyrosine kinase |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 1 | INHERITED FROM: mRNA guanylyltransferase |
47648,52418
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 1 | INHERITED FROM: Polynucleotide 5'-hydroxyl-kinase || RNA-directed RNA polymerase || Nucleotidyltransferases |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Shikimate kinase |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Aspartate kinase |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
52418,54680
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
54680 - Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
57850,48371
57850 - RING/U-box
48371 - ARM repeat | 1 | INHERITED FROM: Mitogen-activated protein kinase kinase kinase |
53633,55729
53633 - Carbamate kinase-like
55729 - Acyl-CoA N-acyltransferases (Nat) | 1 | INHERITED FROM: Acetylglutamate kinase || Phosphotransferases with a carboxy group as acceptor |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
56112,101288
56112 - Protein kinase-like (PK-like)
101288 - L27 domain | 0 | Direct |
55604,51261
55604 - Glucose permease domain IIB
51261 - Duplicated hybrid motif | 0 | Direct |
53850,56112
53850 - Periplasmic binding protein-like II
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55021,56112
55021 - ACT-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53448,51161
53448 - Nucleotide-diphospho-sugar transferases
51161 - Trimeric LpxA-like enzymes | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
54211,55060
54211 - Ribosomal protein S5 domain 2-like
55060 - GHMP Kinase, C-terminal domain | 0 | Direct |
56112,54427
56112 - Protein kinase-like (PK-like)
54427 - NTF2-like | 0 | Direct |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
81301,81891
81301 - Nucleotidyltransferase
81891 - Poly A polymerase C-terminal region-like | 0 | Direct |
103190,47384
103190 - Sensory domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
52374,52540
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,51569
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | Direct |
109604,81301
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase | 0 | Direct |
81631,55003
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
50044,56112
50044 - SH3-domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,47473
56112 - Protein kinase-like (PK-like)
47473 - EF-hand | 0 | Direct |
52374,82114
52374 - Nucleotidylyl transferase
82114 - Riboflavin kinase-like | 0 | Direct |
52540,47648
52540 - P-loop containing nucleoside triphosphate hydrolases
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 0 | Direct |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | Direct |
55608,56672
55608 - Homing endonucleases
56672 - DNA/RNA polymerases | 0 | Direct |
49562,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain | 0 | Direct |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
81593,81891
81593 - Nucleotidyltransferase substrate binding subunit/domain
81891 - Poly A polymerase C-terminal region-like | 0 | Direct |
88697,52374
88697 - PUA domain-like
52374 - Nucleotidylyl transferase | 0 | Direct |
56112,52799
56112 - Protein kinase-like (PK-like)
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
56112,50998
56112 - Protein kinase-like (PK-like)
50998 - Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
55666,46915
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
57889,49562
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
56219,56672
56219 - DNase I-like
56672 - DNA/RNA polymerases | 0 | Direct |
50800,51621
50800 - PK beta-barrel domain-like
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
56784,52540
56784 - HAD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47807,53098
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like | 0 | Direct |
158472,55785
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
55083,51717
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
51717 - Dihydropteroate synthetase-like | 0 | Direct |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
52172,55785
52172 - CheY-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
52949,52540
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
64484,-9
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
-9 - PDB | 0 | Direct |
103575,81296
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
47212,56112
47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55781,47384
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
48452,140931
48452 - TPR-like
140931 - Fic-like | 0 | Direct |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0 | Direct |
56672,100879
56672 - DNA/RNA polymerases
100879 - Lesion bypass DNA polymerase (Y-family), little finger domain | 0 | Direct |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | Direct |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | Direct |
52058,57184
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
55205,52540
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56112,52540
56112 - Protein kinase-like (PK-like)
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53613,48613
53613 - Ribokinase-like
48613 - Heme oxygenase-like | 0 | Direct |
50037,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | Direct |
57184,49265
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
53098,53098
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | Direct |
47370,47370
47370 - Bromodomain
47370 - Bromodomain | 0 | Direct |
56112,50044
56112 - Protein kinase-like (PK-like)
50044 - SH3-domain | 0 | Direct |
52799,56091
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
55804,52794
55804 - Phoshotransferase/anion transport protein
52794 - PTS system IIB component-like | 0 | Direct |
47986,56112
47986 - DEATH domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,48403
56112 - Protein kinase-like (PK-like)
48403 - Ankyrin repeat | 0 | Direct |
82615,82615
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
56112,50978
56112 - Protein kinase-like (PK-like)
50978 - WD40 repeat-like | 0 | Direct |
158472,47384
158472 - HAMP domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
47836,47943
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
55890,55874
55890 - Sporulation response regulatory protein Spo0B
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
64484,64484
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
53613,52374
53613 - Ribokinase-like
52374 - Nucleotidylyl transferase | 0 | Direct |
54277,56112
54277 - CAD & PB1 domains
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49879,56112
49879 - SMAD/FHA domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,47769
56112 - Protein kinase-like (PK-like)
47769 - SAM/Pointed domain | 0 | Direct |
109604,55021
109604 - HD-domain/PDEase-like
55021 - ACT-like | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
88798,50249
88798 - N-terminal, heterodimerisation domain of RBP7 (RpoE)
50249 - Nucleic acid-binding proteins | 0 | Direct |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
52540,53271
52540 - P-loop containing nucleoside triphosphate hydrolases
53271 - PRTase-like | 0 | Direct |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | Direct |
50249,89550
50249 - Nucleic acid-binding proteins
89550 - PHP domain-like | 0 | Direct |
46689,53697
46689 - Homeodomain-like
53697 - SIS domain | 0 | Direct |
52047,56112
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
51621,52935
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like | 0 | Direct |
54197,54197
54197 - HIT-like
54197 - HIT-like | 0 | Direct |
-7,56112
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54277,57889
54277 - CAD & PB1 domains
57889 - Cysteine-rich domain | 0 | Direct |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55874,52172
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like | 0 | Direct |
50249,56300
50249 - Nucleic acid-binding proteins
56300 - Metallo-dependent phosphatases | 0 | Direct |
56672,90234
56672 - DNA/RNA polymerases
90234 - Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
55073,56112
55073 - Nucleotide cyclase
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53850,55785
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
56112,116846
56112 - Protein kinase-like (PK-like)
116846 - MIT domain | 0 | Direct |
55781,55874
55781 - GAF domain-like
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
52172,47226
52172 - CheY-like
47226 - Histidine-containing phosphotransfer domain, HPT domain | 0 | Direct |
56672,46919
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
52047,52047
52047 - RNI-like
52047 - RNI-like | 0 | Direct |
47226,55052
47226 - Histidine-containing phosphotransfer domain, HPT domain
55052 - CheY-binding domain of CheA | 0 | Direct |
52058,49265
52058 - L domain-like
49265 - Fibronectin type III | 0 | Direct |
56112,48452
56112 - Protein kinase-like (PK-like)
48452 - TPR-like | 0 | Direct |
52540,52402
52540 - P-loop containing nucleoside triphosphate hydrolases
52402 - Adenine nucleotide alpha hydrolases-like | 0 | Direct |
56112,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain | 0 | Direct |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
56112,50729
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | Direct |
57184,52058
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | Direct |
88723,47807
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain | 0 | Direct |
53448,69765
53448 - Nucleotide-diphospho-sugar transferases
69765 - IpsF-like | 0 | Direct |
51110,51110
51110 - alpha-D-mannose-specific plant lectins
51110 - alpha-D-mannose-specific plant lectins | 0 | Direct |
81301,81631
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
56796,55205
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like | 0 | Direct |
51621,55804
51621 - Phosphoenolpyruvate/pyruvate domain
55804 - Phoshotransferase/anion transport protein | 0 | Direct |
51391,53613
51391 - Thiamin phosphate synthase
53613 - Ribokinase-like | 0 | Direct |
55594,47831
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
49562,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50729,56112
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55931,48034
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain | 0 | Direct |
50729,69322
50729 - PH domain-like
69322 - Tricorn protease domain 2 | 0 | Direct |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | Direct |
57440,56112
57440 - Kringle-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57774,52540
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
52833,47384
52833 - Thioredoxin-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
55785,55781
55785 - PYP-like sensor domain (PAS domain)
55781 - GAF domain-like | 0 | Direct |
54791,50249
54791 - Eukaryotic type KH-domain (KH-domain type I)
50249 - Nucleic acid-binding proteins | 0 | Direct |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | Direct |
56214,56214
56214 - 4'-phosphopantetheinyl transferase
56214 - 4'-phosphopantetheinyl transferase | 0 | Direct |
101288,101288
101288 - L27 domain
101288 - L27 domain | 0 | Direct |
47473,57889
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | Direct |
46585,49562
46585 - HR1 repeat
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
63999,63862
63999 - Thiamin pyrophosphokinase, catalytic domain
63862 - Thiamin pyrophosphokinase, substrate-binding domain | 0 | Direct |
55785,55890
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B | 0 | Direct |
47802,81585
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like | 0 | Direct |
103190,158472
103190 - Sensory domain-like
158472 - HAMP domain-like | 0 | Direct |
53633,53720
53633 - Carbamate kinase-like
53720 - ALDH-like | 0 | Direct |
55785,47384
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
81301,47473
81301 - Nucleotidyltransferase
47473 - EF-hand | 0 | Direct |
57716,50156
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like | 0 | Direct |
81301,81593
81301 - Nucleotidyltransferase
81593 - Nucleotidyltransferase substrate binding subunit/domain | 0 | Direct |
-9,-7
-9 - PDB
-7 - CATH | 0 | Direct |
81631,81301
81631 - PAP/OAS1 substrate-binding domain
81301 - Nucleotidyltransferase | 0 | Direct |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
48034,55931
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
52540,57802
52540 - P-loop containing nucleoside triphosphate hydrolases
57802 - Rubredoxin-like | 0 | Direct |
52794,52794
52794 - PTS system IIB component-like
52794 - PTS system IIB component-like | 0 | Direct |
56112,50985
56112 - Protein kinase-like (PK-like)
50985 - RCC1/BLIP-II | 0 | Direct |
56112,64268
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | Direct |
53271,53271
53271 - PRTase-like
53271 - PRTase-like | 0 | Direct |
53067,56112
53067 - Actin-like ATPase domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
69012,55874
69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
53756,53067
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53067 - Actin-like ATPase domain | 0 | Direct |
46785,56112
46785 - "Winged helix" DNA-binding domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,90257
56112 - Protein kinase-like (PK-like)
90257 - Myosin rod fragments | 0 | Direct |
46785,82114
46785 - "Winged helix" DNA-binding domain
82114 - Riboflavin kinase-like | 0 | Direct |
143724,56024
143724 - PHP14-like
56024 - Phospholipase D/nuclease | 0 | Direct |
53062,55594
53062 - PTS system fructose IIA component-like
55594 - HPr-like | 0 | Direct |
46585,46585
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
50729,50044
50729 - PH domain-like
50044 - SH3-domain | 0 | Direct |
52009,51621
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
64268,49562
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
55154,56091
55154 - CYTH-like phosphatases
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | Direct |
56672,55608
56672 - DNA/RNA polymerases
55608 - Homing endonucleases | 0 | Direct |
50998,56112
50998 - Quinoprotein alcohol dehydrogenase-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54919,54919
54919 - Nucleoside diphosphate kinase, NDK
54919 - Nucleoside diphosphate kinase, NDK | 0 | Direct |
50965,52540
50965 - Galactose oxidase, central domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
116846,116846
116846 - MIT domain
116846 - MIT domain | 0 | Direct |
49899,56112
49899 - Concanavalin A-like lectins/glucanases
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50156,56112
50156 - PDZ domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56672,51294
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
56112,54928
56112 - Protein kinase-like (PK-like)
54928 - RNA-binding domain, RBD | 0 | Direct |
52087,46966
52087 - CRAL/TRIO domain
46966 - Spectrin repeat | 0 | Direct |
57889,50729
57889 - Cysteine-rich domain
50729 - PH domain-like | 0 | Direct |
82549,101473
82549 - DAK1/DegV-like
101473 - DhaL-like | 0 | Direct |
140356,143724
140356 - PPK N-terminal domain-like
143724 - PHP14-like | 0 | Direct |
49562,48350
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48350 - GTPase activation domain, GAP | 0 | Direct |
53448,51182
53448 - Nucleotide-diphospho-sugar transferases
51182 - RmlC-like cupins | 0 | Direct |
51294,56672
51294 - Hedgehog/intein (Hint) domain
56672 - DNA/RNA polymerases | 0 | Direct |
52794,55804
52794 - PTS system IIB component-like
55804 - Phoshotransferase/anion transport protein | 0 | Direct |
54236,57889
54236 - Ubiquitin-like
57889 - Cysteine-rich domain | 0 | Direct |
81585,81301
81585 - PsbU/PolX domain-like
81301 - Nucleotidyltransferase | 0 | Direct |
81995,56112
81995 - beta-sandwich domain of Sec23/24
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | Direct |
50465,52540
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
55257,47789
55257 - RBP11-like subunits of RNA polymerase
47789 - C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
52058,52540
52058 - L domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | Direct |
52058,56112
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55666,54791
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
57889,111331
57889 - Cysteine-rich domain
111331 - NAD kinase/diacylglycerol kinase-like | 0 | Direct |
54236,56112
54236 - Ubiquitin-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53633,55021
53633 - Carbamate kinase-like
55021 - ACT-like | 0 | Direct |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
50729,57889
50729 - PH domain-like
57889 - Cysteine-rich domain | 0 | Direct |
55874,50341
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
50341 - CheW-like | 0 | Direct |
53448,52266
53448 - Nucleotide-diphospho-sugar transferases
52266 - SGNH hydrolase | 0 | Direct |
56553,55257
56553 - Insert subdomain of RNA polymerase alpha subunit
55257 - RBP11-like subunits of RNA polymerase | 0 | Direct |
55620,55083
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
49265,56112
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49265,63825
49265 - Fibronectin type III
63825 - YWTD domain | 0 | Direct |
51735,52540
51735 - NAD(P)-binding Rossmann-fold domains
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
82185,82185
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
56112,103243
56112 - Protein kinase-like (PK-like)
103243 - KA1-like | 0 | Direct |
50447,50465
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
51569,53223
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
47807,56672
47807 - 5' to 3' exonuclease, C-terminal subdomain
56672 - DNA/RNA polymerases | 0 | Direct |
53448,56784
53448 - Nucleotide-diphospho-sugar transferases
56784 - HAD-like | 0 | Direct |
89550,53098
89550 - PHP domain-like
53098 - Ribonuclease H-like | 0 | Direct |
52540,57774
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
55021,51735
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
48097,56112
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,57716
52540 - P-loop containing nucleoside triphosphate hydrolases
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
55052,47384
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
55781,55785
55781 - GAF domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
63825,49265
63825 - YWTD domain
49265 - Fibronectin type III | 0 | Direct |
50044,48065
50044 - SH3-domain
48065 - DBL homology domain (DH-domain) | 0 | Direct |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | Direct |
56112,48726
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin | 0 | Direct |
52540,88697
52540 - P-loop containing nucleoside triphosphate hydrolases
88697 - PUA domain-like | 0 | Direct |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | Direct |
53633,88697
53633 - Carbamate kinase-like
88697 - PUA domain-like | 0 | Direct |
103190,55785
103190 - Sensory domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
89837,89837
89837 - Doublecortin (DC)
89837 - Doublecortin (DC) | 0 | Direct |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
47831,52009
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain | 0 | Direct |
48726,56112
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | Direct |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
64268,56112
64268 - PX domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52113,47802
52113 - BRCT domain
47802 - DNA polymerase beta, N-terminal domain-like | 0 | Direct |
81631,57756
81631 - PAP/OAS1 substrate-binding domain
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
46915,54211
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
52540,81301
52540 - P-loop containing nucleoside triphosphate hydrolases
81301 - Nucleotidyltransferase | 0 | Direct |
54593,53784
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
53784 - Phosphofructokinase | 0 | Direct |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | Direct |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57667,54928
57667 - beta-beta-alpha zinc fingers
54928 - RNA-binding domain, RBD | 0 | Direct |
56112,56112
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
48065,50729
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
53784,53784
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | Direct |
52935,52009
52935 - PK C-terminal domain-like
52009 - Phosphohistidine domain | 0 | Direct |
55021,55021
55021 - ACT-like
55021 - ACT-like | 0 | Direct |
56112,55681
56112 - Protein kinase-like (PK-like)
55681 - Class II aaRS and biotin synthetases | 0 | Direct |
48403,56112
48403 - Ankyrin repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81891,109604
81891 - Poly A polymerase C-terminal region-like
109604 - HD-domain/PDEase-like | 0 | Direct |
47391,52540
47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47384,55874
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
56059,52009
56059 - Glutathione synthetase ATP-binding domain-like
52009 - Phosphohistidine domain | 0 | Direct |
53613,51391
53613 - Ribokinase-like
51391 - Thiamin phosphate synthase | 0 | Direct |
52172,52172
52172 - CheY-like
52172 - CheY-like | 0 | Direct |
52047,52058
52047 - RNI-like
52058 - L domain-like | 0 | Direct |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.000000000000001059 | Direct |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0.00000000000000246 | Direct |
52058,52047
52058 - L domain-like
52047 - RNI-like | 0.000000000000007682 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0.000000000000008377 | Direct |
81301,81271
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.00000000000002681 | Direct |
50729,55550
50729 - PH domain-like
55550 - SH2 domain | 0.00000000000008799 | Direct |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0.000000000007432 | Direct |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.000000000007432 | Direct |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.000000000007432 | Direct |
51206,56112
51206 - cAMP-binding domain-like
56112 - Protein kinase-like (PK-like) | 0.00000000002565 | Direct |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0.0000000000293 | Direct |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.0000000003026 | Direct |
52374,52374
52374 - Nucleotidylyl transferase
52374 - Nucleotidylyl transferase | 0.000001297 | Direct |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.000002456 | Direct |
55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0.000006963 | Direct |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.000009738 | Direct |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0.00001049 | Direct |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0.00001843 | Direct |
48371,48371
48371 - ARM repeat
48371 - ARM repeat | 0.00002935 | Direct |
57756,51283
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0.0000946 | Direct |
51283,50630
51283 - dUTPase-like
50630 - Acid proteases | 0.0000946 | Direct |
57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0.0001575 | Direct |
53850,53850
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II | 0.0003032 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.0003791 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0.0005992 | Direct |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.0007132 | Direct |
55785,55073
55785 - PYP-like sensor domain (PAS domain)
55073 - Nucleotide cyclase | 0.002588 | Inherited |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0.003282 | Inherited |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.006742 | Inherited |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.022 | Inherited |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0.02407 | Inherited |
55681,50037
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors | 0.02407 | Inherited |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.03527 | Inherited |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0.03807 | Inherited |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0.05024 | Inherited |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.07724 | Inherited |
-9,-9
-9 - PDB
-9 - PDB | 0.1061 | Inherited |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.1941 | Inherited |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 0.3075 | Inherited |
48403,47769
48403 - Ankyrin repeat
47769 - SAM/Pointed domain | 0.3131 | Inherited |
63882,53218
63882 - MoeA N-terminal region -like
53218 - Molybdenum cofactor biosynthesis proteins | 0.6919 | Inherited |
53218,63867
53218 - Molybdenum cofactor biosynthesis proteins
63867 - MoeA C-terminal domain-like | 0.6919 | Inherited |
55326,56042
55326 - PurM N-terminal domain-like
56042 - PurM C-terminal domain-like | 0.7156 | Inherited |
55620,55620
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55620 - Tetrahydrobiopterin biosynthesis enzymes-like | 0.8009 | Inherited |
81296,81296
81296 - E set domains
81296 - E set domains | 1 | Inherited |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 1 | Inherited |
47648,52418
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 1 | Inherited |
53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 1 | Inherited |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 1 | Inherited |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
51735,55347
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | Inherited |
53738,55957
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 1 | Inherited |
52418,54680
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
54680 - Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | Inherited |
57850,48371
57850 - RING/U-box
48371 - ARM repeat | 1 | Inherited |
53633,55729
53633 - Carbamate kinase-like
55729 - Acyl-CoA N-acyltransferases (Nat) | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (SPEC level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52058,52047,52058
52058 - L domain-like
52047 - RNI-like
52058 - L domain-like | 0 | DIRECT |
48065,50729,50044
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50044 - SH3-domain | 0 | DIRECT |
89043,50494,56672
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
47031,50729,55550
47031 - Second domain of FERM
50729 - PH domain-like
55550 - SH2 domain | 0 | DIRECT |
50447,50465,52540
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50729,50044,55550
50729 - PH domain-like
50044 - SH3-domain
55550 - SH2 domain | 0 | DIRECT |
55681,50037,53067
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | DIRECT |
52540,51569,53223
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
55608,56672,51294
55608 - Homing endonucleases
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
55052,47384,55874
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
57774,52540,57774
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | DIRECT |
51283,46919,53098
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
57889,57889,111331
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
111331 - NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53098,56672,90234
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases
90234 - Zinc finger domain of DNA polymerase-alpha | 0 | DIRECT |
50800,51621,52935
50800 - PK beta-barrel domain-like
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like | 0 | DIRECT |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | DIRECT |
46915,54211,55666
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
50630,56672,53098
50630 - Acid proteases
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | DIRECT |
53850,53850,55785
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
88723,47807,56672
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain
56672 - DNA/RNA polymerases | 0 | DIRECT |
52949,52540,52540
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,88697,52374
52540 - P-loop containing nucleoside triphosphate hydrolases
88697 - PUA domain-like
52374 - Nucleotidylyl transferase | 0 | DIRECT |
50630,56672,46919
50630 - Acid proteases
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
48097,56112,50729
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | DIRECT |
55666,46915,54211
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
50044,48065,50729
50044 - SH3-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | DIRECT |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | DIRECT |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
53098,56672,51294
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
49265,56112,48726
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin | 0 | DIRECT |
48034,55931,48034
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain | 0 | DIRECT |
50494,52540,89043
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
52540,57774,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51294,56672,55608
51294 - Hedgehog/intein (Hint) domain
56672 - DNA/RNA polymerases
55608 - Homing endonucleases | 0 | DIRECT |
52949,52540,56672
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
56672,53098,51283
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | DIRECT |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57889,49562,56112
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55785,55890,55874
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
47802,81585,81301
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like
81301 - Nucleotidyltransferase | 0 | DIRECT |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
50494,52540,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55620,55083,51717
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
51717 - Dihydropteroate synthetase-like | 0 | DIRECT |
55205,52540,51569
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | DIRECT |
52113,47802,81585
52113 - BRCT domain
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like | 0 | DIRECT |
103190,55785,55890
103190 - Sensory domain-like
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B | 0 | DIRECT |
47836,47943,47353
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | DIRECT |
55931,48034,55931
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | DIRECT |
81301,81631,81301
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
81301 - Nucleotidyltransferase | 0 | DIRECT |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
51197,52540,56672
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
57716,50156,56112
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56553,55257,47789
56553 - Insert subdomain of RNA polymerase alpha subunit
55257 - RBP11-like subunits of RNA polymerase
47789 - C-terminal domain of RNA polymerase alpha subunit | 0 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
55785,47384,55874
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
53062,55594,47831
53062 - PTS system fructose IIA component-like
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | DIRECT |
-9,-9,-9
-9 - PDB
-9 - PDB
-9 - PDB | 0 | DIRECT |
52058,52058,56112
52058 - L domain-like
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
50037,53067,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | DIRECT |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
53850,53850,56112
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
48371,56112,64268
48371 - ARM repeat
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | DIRECT |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | DIRECT |
52009,51621,55804
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain
55804 - Phoshotransferase/anion transport protein | 0 | DIRECT |
57184,52058,49265
57184 - Growth factor receptor domain
52058 - L domain-like
49265 - Fibronectin type III | 0 | DIRECT |
56672,53098,46919
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
47384,55874,52172
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like | 0 | DIRECT |
47353,57756,50630
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
101288,101288,50156
101288 - L27 domain
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
55666,54791,50249
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I)
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
158472,47384,55874
158472 - HAMP domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
56672,53098,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | DIRECT |
109604,55021,55021
109604 - HD-domain/PDEase-like
55021 - ACT-like
55021 - ACT-like | 0 | DIRECT |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | DIRECT |
56672,52540,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50494,56672,88633
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
-9,-7,56112
-9 - PDB
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
53850,55785,47384
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
64484,-9,-9
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
-9 - PDB
-9 - PDB | 0 | DIRECT |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56059,52009,51621
56059 - Glutathione synthetase ATP-binding domain-like
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
55021,51735,55347
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | DIRECT |
55785,55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
51621,52935,52009
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like
52009 - Phosphohistidine domain | 0 | DIRECT |
55874,52172,47226
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like
47226 - Histidine-containing phosphotransfer domain, HPT domain | 0 | DIRECT |
52087,46966,46966
52087 - CRAL/TRIO domain
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
51569,53223,51735
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
52047,52047,52058
52047 - RNI-like
52047 - RNI-like
52058 - L domain-like | 0 | DIRECT |
47831,52009,51621
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | DIRECT |
57716,57716,50156
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like | 0 | DIRECT |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
47384,55874,50341
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
50341 - CheW-like | 0 | DIRECT |
50729,57889,57889
50729 - PH domain-like
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
56112,101288,101288
56112 - Protein kinase-like (PK-like)
101288 - L27 domain
101288 - L27 domain | 0 | DIRECT |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
88723,47807,53098
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like | 0 | DIRECT |
88633,50494,52540
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52172,55785,47384
52172 - CheY-like
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
54593,53784,53784
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | DIRECT |
56112,52799,49562
56112 - Protein kinase-like (PK-like)
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
56672,55608,56672
56672 - DNA/RNA polymerases
55608 - Homing endonucleases
56672 - DNA/RNA polymerases | 0 | DIRECT |
47031,50729,56112
47031 - Second domain of FERM
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54211,55666,54791
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
47473,47473,57889
47473 - EF-hand
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | DIRECT |
56112,116846,116846
56112 - Protein kinase-like (PK-like)
116846 - MIT domain
116846 - MIT domain | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
50494,52540,56672
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
158472,55785,47384
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
51283,50630,56672
51283 - dUTPase-like
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
52058,52047,56112
52058 - L domain-like
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56672,53098,50122
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
88697,52374,52540
88697 - PUA domain-like
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53633,55021,55021
53633 - Carbamate kinase-like
55021 - ACT-like
55021 - ACT-like | 0 | DIRECT |
50249,89550,53098
50249 - Nucleic acid-binding proteins
89550 - PHP domain-like
53098 - Ribonuclease H-like | 0 | DIRECT |
81631,81301,81631
81631 - PAP/OAS1 substrate-binding domain
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
56672,46919,53098
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
56112,64268,49562
56112 - Protein kinase-like (PK-like)
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
47226,55052,47384
47226 - Histidine-containing phosphotransfer domain, HPT domain
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
55021,55021,51735
55021 - ACT-like
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
103190,47384,55874
103190 - Sensory domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
109604,81301,47473
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase
47473 - EF-hand | 0 | DIRECT |
55781,55781,47384
55781 - GAF domain-like
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
81891,109604,55021
81891 - Poly A polymerase C-terminal region-like
109604 - HD-domain/PDEase-like
55021 - ACT-like | 0 | DIRECT |
103190,158472,55785
103190 - Sensory domain-like
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
55785,55785,47384
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | DIRECT |
56796,55205,52540
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55620,55620,55083
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | DIRECT |
47807,53098,56672
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | DIRECT |
53098,51283,46919
53098 - Ribonuclease H-like
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
52833,47384,55874
52833 - Thioredoxin-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
52540,47648,52418
52540 - P-loop containing nucleoside triphosphate hydrolases
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | DIRECT |
88633,88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
47473,57889,57889
47473 - EF-hand
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
55781,47384,55874
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | DIRECT |
52047,52058,56112
52047 - RNI-like
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
143724,56024,56024
143724 - PHP14-like
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
53098,46919,53098
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
48726,48726,56112
48726 - Immunoglobulin
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56112,48726,48726
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
52799,56091,50249
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | DIRECT |
55785,55781,55781
55785 - PYP-like sensor domain (PAS domain)
55781 - GAF domain-like
55781 - GAF domain-like | 0 | DIRECT |
54236,54236,56112
54236 - Ubiquitin-like
54236 - Ubiquitin-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
55594,47831,52009
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain | 0 | DIRECT |
55874,52172,52172
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like
52172 - CheY-like | 0 | DIRECT |
47943,47353,57756
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
47391,52540,52540
47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
63825,49265,63825
63825 - YWTD domain
49265 - Fibronectin type III
63825 - YWTD domain | 0 | DIRECT |
57756,50630,56672
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
52540,52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
54211,55666,46915
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | DIRECT |
81301,81631,57756
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
52058,49265,49265
52058 - L domain-like
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
46919,53098,50122
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
52540,89043,50494
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | DIRECT |
56112,48403,52540
56112 - Protein kinase-like (PK-like)
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54001,88633,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
52540,52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | DIRECT |
55874,52172,55785
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
140356,143724,56024
140356 - PPK N-terminal domain-like
143724 - PHP14-like
56024 - Phospholipase D/nuclease | 0 | DIRECT |
101912,103575,81296
101912 - Sema domain
103575 - Plexin repeat
81296 - E set domains | 0 | DIRECT |
52047,52047,56112
52047 - RNI-like
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
81301,81593,81891
81301 - Nucleotidyltransferase
81593 - Nucleotidyltransferase substrate binding subunit/domain
81891 - Poly A polymerase C-terminal region-like | 0 | DIRECT |
52058,57184,57184
52058 - L domain-like
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57889,50729,69322
57889 - Cysteine-rich domain
50729 - PH domain-like
69322 - Tricorn protease domain 2 | 0 | DIRECT |
109604,81301,81271
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.00000000000002681 | DIRECT |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.000000000004034 | DIRECT |
143076,101816,144246
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.000000000007432 | DIRECT |
140367,143076,101816
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.000000000007432 | DIRECT |
51206,51206,56112
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like
56112 - Protein kinase-like (PK-like) | 0.00000000002565 | DIRECT |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.0000000001526 | DIRECT |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.000005806 | DIRECT |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0.00001441 | DIRECT |
57756,51283,50630
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like
50630 - Acid proteases | 0.0000946 | DIRECT |
57756,57756,51283
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0.0007378 | DIRECT |
47353,57756,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.0007378 | DIRECT |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.001671 | INHERITED FROM: Protein-tyrosine kinases || Receptor protein-tyrosine kinase |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0.03527 | INHERITED FROM: Protein-tyrosine kinases || Non-specific protein-tyrosine kinase |
63882,53218,63867
63882 - MoeA N-terminal region -like
53218 - Molybdenum cofactor biosynthesis proteins
63867 - MoeA C-terminal domain-like | 0.6919 | INHERITED FROM: Molybdopterin adenylyltransferase || Nucleotidyltransferases |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 1 | INHERITED FROM: Glucose-1,6-bisphosphate synthase |
47648,52418,54680
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
54680 - Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | INHERITED FROM: Ribose 1,5-bisphosphate phosphokinase |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
52058,52047,52058
52058 - L domain-like
52047 - RNI-like
52058 - L domain-like | 0 | Direct |
48065,50729,50044
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like
50044 - SH3-domain | 0 | Direct |
89043,50494,56672
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | Direct |
47031,50729,55550
47031 - Second domain of FERM
50729 - PH domain-like
55550 - SH2 domain | 0 | Direct |
50447,50465,52540
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50729,50044,55550
50729 - PH domain-like
50044 - SH3-domain
55550 - SH2 domain | 0 | Direct |
55681,50037,53067
55681 - Class II aaRS and biotin synthetases
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain | 0 | Direct |
52540,51569,53223
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
55608,56672,51294
55608 - Homing endonucleases
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
103575,81296,81296
103575 - Plexin repeat
81296 - E set domains
81296 - E set domains | 0 | Direct |
55052,47384,55874
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
57774,52540,57774
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain | 0 | Direct |
51283,46919,53098
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
57889,57889,111331
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
111331 - NAD kinase/diacylglycerol kinase-like | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53098,56672,90234
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases
90234 - Zinc finger domain of DNA polymerase-alpha | 0 | Direct |
50800,51621,52935
50800 - PK beta-barrel domain-like
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like | 0 | Direct |
46585,46585,46585
46585 - HR1 repeat
46585 - HR1 repeat
46585 - HR1 repeat | 0 | Direct |
46915,54211,55666
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
50630,56672,53098
50630 - Acid proteases
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | Direct |
53850,53850,55785
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
88723,47807,56672
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain
56672 - DNA/RNA polymerases | 0 | Direct |
52949,52540,52540
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,88697,52374
52540 - P-loop containing nucleoside triphosphate hydrolases
88697 - PUA domain-like
52374 - Nucleotidylyl transferase | 0 | Direct |
50630,56672,46919
50630 - Acid proteases
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
48097,56112,50729
48097 - Regulator of G-protein signaling, RGS
56112 - Protein kinase-like (PK-like)
50729 - PH domain-like | 0 | Direct |
55666,46915,54211
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
50044,48065,50729
50044 - SH3-domain
48065 - DBL homology domain (DH-domain)
50729 - PH domain-like | 0 | Direct |
49785,57184,49265
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain
49265 - Fibronectin type III | 0 | Direct |
57889,57889,49562
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
53098,56672,51294
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
49265,56112,48726
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin | 0 | Direct |
48034,55931,48034
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain | 0 | Direct |
50494,52540,89043
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
52540,57774,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51294,56672,55608
51294 - Hedgehog/intein (Hint) domain
56672 - DNA/RNA polymerases
55608 - Homing endonucleases | 0 | Direct |
52949,52540,56672
52949 - Macro domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
56672,53098,51283
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | Direct |
55550,56112,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57889,49562,56112
57889 - Cysteine-rich domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55785,55890,55874
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
47802,81585,81301
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like
81301 - Nucleotidyltransferase | 0 | Direct |
48726,49265,48726
48726 - Immunoglobulin
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
50494,52540,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55620,55083,51717
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
51717 - Dihydropteroate synthetase-like | 0 | Direct |
55205,52540,51569
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases
51569 - Aldolase | 0 | Direct |
52113,47802,81585
52113 - BRCT domain
47802 - DNA polymerase beta, N-terminal domain-like
81585 - PsbU/PolX domain-like | 0 | Direct |
103190,55785,55890
103190 - Sensory domain-like
55785 - PYP-like sensor domain (PAS domain)
55890 - Sporulation response regulatory protein Spo0B | 0 | Direct |
47836,47943,47353
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | Direct |
55931,48034,55931
55931 - Glutamine synthetase/guanido kinase
48034 - Guanido kinase N-terminal domain
55931 - Glutamine synthetase/guanido kinase | 0 | Direct |
81301,81631,81301
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
81301 - Nucleotidyltransferase | 0 | Direct |
49562,57889,57889
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
51197,52540,56672
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
57716,50156,56112
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56553,55257,47789
56553 - Insert subdomain of RNA polymerase alpha subunit
55257 - RBP11-like subunits of RNA polymerase
47789 - C-terminal domain of RNA polymerase alpha subunit | 0 | Direct |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
55785,47384,55874
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
53062,55594,47831
53062 - PTS system fructose IIA component-like
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | 0 | Direct |
-9,-9,-9
-9 - PDB
-9 - PDB
-9 - PDB | 0 | Direct |
52058,52058,56112
52058 - L domain-like
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
50037,53067,53067
50037 - C-terminal domain of transcriptional repressors
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0 | Direct |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
53850,53850,56112
53850 - Periplasmic binding protein-like II
53850 - Periplasmic binding protein-like II
56112 - Protein kinase-like (PK-like) | 0 | Direct |
48371,56112,64268
48371 - ARM repeat
56112 - Protein kinase-like (PK-like)
64268 - PX domain | 0 | Direct |
52058,57184,52058
52058 - L domain-like
57184 - Growth factor receptor domain
52058 - L domain-like | 0 | Direct |
52009,51621,55804
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain
55804 - Phoshotransferase/anion transport protein | 0 | Direct |
57184,52058,49265
57184 - Growth factor receptor domain
52058 - L domain-like
49265 - Fibronectin type III | 0 | Direct |
56672,53098,46919
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
47384,55874,52172
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like | 0 | Direct |
47353,57756,50630
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
101288,101288,50156
101288 - L27 domain
101288 - L27 domain
50156 - PDZ domain-like | 0 | Direct |
55666,54791,50249
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I)
50249 - Nucleic acid-binding proteins | 0 | Direct |
158472,47384,55874
158472 - HAMP domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
56672,53098,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | Direct |
109604,55021,55021
109604 - HD-domain/PDEase-like
55021 - ACT-like
55021 - ACT-like | 0 | Direct |
56112,82615,82615
56112 - Protein kinase-like (PK-like)
82615 - Polo-box domain
82615 - Polo-box domain | 0 | Direct |
56672,52540,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50494,56672,88633
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
48726,49265,56112
48726 - Immunoglobulin
49265 - Fibronectin type III
56112 - Protein kinase-like (PK-like) | 0 | Direct |
-9,-7,56112
-9 - PDB
-7 - CATH
56112 - Protein kinase-like (PK-like) | 0 | Direct |
53850,55785,47384
53850 - Periplasmic binding protein-like II
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
49265,48726,49265
49265 - Fibronectin type III
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
64484,-9,-9
64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
-9 - PDB
-9 - PDB | 0 | Direct |
50729,55550,56112
50729 - PH domain-like
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56059,52009,51621
56059 - Glutathione synthetase ATP-binding domain-like
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
55021,51735,55347
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains
55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 0 | Direct |
55785,55785,55785
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
51621,52935,52009
51621 - Phosphoenolpyruvate/pyruvate domain
52935 - PK C-terminal domain-like
52009 - Phosphohistidine domain | 0 | Direct |
55874,52172,47226
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like
47226 - Histidine-containing phosphotransfer domain, HPT domain | 0 | Direct |
52087,46966,46966
52087 - CRAL/TRIO domain
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
51569,53223,51735
51569 - Aldolase
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
52047,52047,52058
52047 - RNI-like
52047 - RNI-like
52058 - L domain-like | 0 | Direct |
47831,52009,51621
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain
51621 - Phosphoenolpyruvate/pyruvate domain | 0 | Direct |
57716,57716,50156
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
50156 - PDZ domain-like | 0 | Direct |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
47384,55874,50341
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
50341 - CheW-like | 0 | Direct |
50729,57889,57889
50729 - PH domain-like
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
56112,101288,101288
56112 - Protein kinase-like (PK-like)
101288 - L27 domain
101288 - L27 domain | 0 | Direct |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
88723,47807,53098
88723 - PIN domain-like
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like | 0 | Direct |
88633,50494,52540
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52172,55785,47384
52172 - CheY-like
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
54593,53784,53784
54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
53784 - Phosphofructokinase
53784 - Phosphofructokinase | 0 | Direct |
56112,52799,49562
56112 - Protein kinase-like (PK-like)
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
56672,55608,56672
56672 - DNA/RNA polymerases
55608 - Homing endonucleases
56672 - DNA/RNA polymerases | 0 | Direct |
47031,50729,56112
47031 - Second domain of FERM
50729 - PH domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54211,55666,54791
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
47473,47473,57889
47473 - EF-hand
47473 - EF-hand
57889 - Cysteine-rich domain | 0 | Direct |
56112,116846,116846
56112 - Protein kinase-like (PK-like)
116846 - MIT domain
116846 - MIT domain | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52540,50447,50465
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
50494,52540,56672
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
158472,55785,47384
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
51283,50630,56672
51283 - dUTPase-like
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
57184,52058,57184
57184 - Growth factor receptor domain
52058 - L domain-like
57184 - Growth factor receptor domain | 0 | Direct |
52058,52047,56112
52058 - L domain-like
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56672,53098,50122
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
88697,52374,52540
88697 - PUA domain-like
52374 - Nucleotidylyl transferase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53633,55021,55021
53633 - Carbamate kinase-like
55021 - ACT-like
55021 - ACT-like | 0 | Direct |
50249,89550,53098
50249 - Nucleic acid-binding proteins
89550 - PHP domain-like
53098 - Ribonuclease H-like | 0 | Direct |
81631,81301,81631
81631 - PAP/OAS1 substrate-binding domain
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
56672,46919,53098
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
56112,64268,49562
56112 - Protein kinase-like (PK-like)
64268 - PX domain
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
47226,55052,47384
47226 - Histidine-containing phosphotransfer domain, HPT domain
55052 - CheY-binding domain of CheA
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
55021,55021,51735
55021 - ACT-like
55021 - ACT-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
103190,47384,55874
103190 - Sensory domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
109604,81301,47473
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase
47473 - EF-hand | 0 | Direct |
55781,55781,47384
55781 - GAF domain-like
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
81891,109604,55021
81891 - Poly A polymerase C-terminal region-like
109604 - HD-domain/PDEase-like
55021 - ACT-like | 0 | Direct |
103190,158472,55785
103190 - Sensory domain-like
158472 - HAMP domain-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
55785,55785,47384
55785 - PYP-like sensor domain (PAS domain)
55785 - PYP-like sensor domain (PAS domain)
47384 - Homodimeric domain of signal transducing histidine kinase | 0 | Direct |
56796,55205,52540
56796 - Dehydroquinate synthase-like
55205 - EPT/RTPC-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55620,55620,55083
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55620 - Tetrahydrobiopterin biosynthesis enzymes-like
55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | 0 | Direct |
47807,53098,56672
47807 - 5' to 3' exonuclease, C-terminal subdomain
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 0 | Direct |
53098,51283,46919
53098 - Ribonuclease H-like
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
52833,47384,55874
52833 - Thioredoxin-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
52540,47648,52418
52540 - P-loop containing nucleoside triphosphate hydrolases
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0 | Direct |
88633,88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
47473,57889,57889
47473 - EF-hand
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
55781,47384,55874
55781 - GAF domain-like
47384 - Homodimeric domain of signal transducing histidine kinase
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0 | Direct |
52047,52058,56112
52047 - RNI-like
52058 - L domain-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
143724,56024,56024
143724 - PHP14-like
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
53098,46919,53098
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
48726,48726,56112
48726 - Immunoglobulin
48726 - Immunoglobulin
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56112,48726,48726
56112 - Protein kinase-like (PK-like)
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
50044,55550,56112
50044 - SH3-domain
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
52799,56091,50249
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
81301,81631,55003
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0 | Direct |
55785,55781,55781
55785 - PYP-like sensor domain (PAS domain)
55781 - GAF domain-like
55781 - GAF domain-like | 0 | Direct |
54236,54236,56112
54236 - Ubiquitin-like
54236 - Ubiquitin-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
55594,47831,52009
55594 - HPr-like
47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
52009 - Phosphohistidine domain | 0 | Direct |
55874,52172,52172
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like
52172 - CheY-like | 0 | Direct |
47943,47353,57756
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
47391,52540,52540
47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
63825,49265,63825
63825 - YWTD domain
49265 - Fibronectin type III
63825 - YWTD domain | 0 | Direct |
57756,50630,56672
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | Direct |
52540,52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
54211,55666,46915
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like
46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0 | Direct |
81301,81631,57756
81301 - Nucleotidyltransferase
81631 - PAP/OAS1 substrate-binding domain
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
52058,49265,49265
52058 - L domain-like
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
46919,53098,50122
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
52540,89043,50494
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | Direct |
56112,48403,52540
56112 - Protein kinase-like (PK-like)
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54001,88633,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
52540,52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | Direct |
55874,52172,55785
55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
52172 - CheY-like
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
140356,143724,56024
140356 - PPK N-terminal domain-like
143724 - PHP14-like
56024 - Phospholipase D/nuclease | 0 | Direct |
101912,103575,81296
101912 - Sema domain
103575 - Plexin repeat
81296 - E set domains | 0 | Direct |
52047,52047,56112
52047 - RNI-like
52047 - RNI-like
56112 - Protein kinase-like (PK-like) | 0 | Direct |
81301,81593,81891
81301 - Nucleotidyltransferase
81593 - Nucleotidyltransferase substrate binding subunit/domain
81891 - Poly A polymerase C-terminal region-like | 0 | Direct |
52058,57184,57184
52058 - L domain-like
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57889,50729,69322
57889 - Cysteine-rich domain
50729 - PH domain-like
69322 - Tricorn protease domain 2 | 0 | Direct |
109604,81301,81271
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.00000000000002681 | Direct |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.000000000004034 | Direct |
143076,101816,144246
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0.000000000007432 | Direct |
140367,143076,101816
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0.000000000007432 | Direct |
51206,51206,56112
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like
56112 - Protein kinase-like (PK-like) | 0.00000000002565 | Direct |
52058,48726,48726
52058 - L domain-like
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.0000000001526 | Direct |
53067,53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 0.000005806 | Direct |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0.00001441 | Direct |
57756,51283,50630
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like
50630 - Acid proteases | 0.0000946 | Direct |
57756,57756,51283
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0.0007378 | Direct |
47353,57756,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.0007378 | Direct |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.001671 | Inherited |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0.03527 | Inherited |
63882,53218,63867
63882 - MoeA N-terminal region -like
53218 - Molybdenum cofactor biosynthesis proteins
63867 - MoeA C-terminal domain-like | 0.6919 | Inherited |
53738,53738,53738
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains | 1 | Inherited |
53738,53738,55957
53738 - Phosphoglucomutase, first 3 domains
53738 - Phosphoglucomutase, first 3 domains
55957 - Phosphoglucomutase, C-terminal domain | 1 | Inherited |
47648,52418,54680
47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
54680 - Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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