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  Home > Phenotype Ontology > Protein-serine/threonine kinases

Enzyme Commission (EC): Protein-serine/threonine kinases

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Transferases [2] <10>(445|680) (444|535|275)
+ 1:   Transferring phosphorus-containing groups [2.7] <15>(255|337) (254|318|190)
0:   Protein-serine/threonine kinases [2.7.11] <35>(59|62) (58|92|40)
- 1:   Calcium/calmodulin-dependent protein kinase [2.7.11.17](1|1) (1|1|0)
- 1:   Cyclin-dependent kinase [2.7.11.22](0|0) (0|0|0)
- 1:   Dephospho-[reductase kinase] kinase [2.7.11.3](0|0) (0|0|0)
- 1:   Fas-activated serine/threonine kinase [2.7.11.8](0|0) (0|0|0)
- 1:   I-kappa-B kinase [2.7.11.10](0|0) (0|0|0)
- 1:   Mitogen-activated protein kinase [2.7.11.24](0|0) (0|0|0)
- 1:   Mitogen-activated protein kinase kinase kinase [2.7.11.25](3|3) (3|2|0)
- 1:   Non-specific serine/threonine protein kinase [2.7.11.1](34|39) (34|61|25)
- 1:   Phosphorylase kinase [2.7.11.19](0|0) (0|0|0)
- 1:   Polo kinase [2.7.11.21](1|2) (1|2|1)
- 1:   Protein kinase C [2.7.11.13](5|6) (5|8|4)
- 1:   Receptor protein serine/threonine kinase [2.7.11.30](1|1) (1|0|0)
- 1:   Rhodopsin kinase [2.7.11.14](1|1) (1|1|0)
- 1:   Transferred entry: 2.7.11.32 [2.7.11.n1](0|0) (0|0|0)
- 1:   Transferred entry: 2.7.11.33 [2.7.11.n2](0|0) (0|0|0)
- 1:   Tropomyosin kinase [2.7.11.28](0|0) (0|0|0)
- 1:   [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase [2.7.11.4](2|2) (2|1|0)
- 1:   [Acetyl-CoA carboxylase] kinase [2.7.11.27](1|1) (1|1|0)
- 1:   [Beta-adrenergic-receptor] kinase [2.7.11.15](2|2) (2|2|1)
- 1:   [Elongation factor 2] kinase [2.7.11.20](1|1) (1|0|0)
- 1:   [G-protein-coupled receptor] kinase [2.7.11.16](1|1) (1|1|0)
- 1:   [Goodpasture-antigen-binding protein] kinase [2.7.11.9](0|0) (0|0|0)
- 1:   [Hydroxymethylglutaryl-CoA reductase (NADPH)] kinase [2.7.11.31](1|1) (1|1|0)
- 1:   [Isocitrate dehydrogenase (NADP(+))] kinase [2.7.11.5](0|0) (0|0|0)
- 1:   [Low-density-lipoprotein receptor] kinase [2.7.11.29](0|0) (0|0|0)
- 1:   [Myosin heavy-chain] kinase [2.7.11.7](1|2) (1|0|0)
- 1:   [Myosin light-chain] kinase [2.7.11.18](2|2) (2|4|4)
- 1:   [Pyruvate dehydrogenase (acetyl-transferring)] kinase [2.7.11.2](2|2) (2|1|0)
- 1:   [Pyruvate, phosphate dikinase] kinase [2.7.11.32](1|0) (1|0|0)
- 1:   [Pyruvate, water dikinase] kinase [2.7.11.33](1|0) (1|0|0)
- 1:   [RNA-polymerase]-subunit kinase [2.7.11.23](0|0) (0|0|0)
- 1:   [Tau protein] kinase [2.7.11.26](1|2) (1|1|0)
- 1:   [Tyrosine 3-monooxygenase] kinase [2.7.11.6](0|0) (0|0|0)
- 1:   cAMP-dependent protein kinase [2.7.11.11](1|0) (0|1|0)
- 1:   cGMP-dependent protein kinase [2.7.11.12](1|1) (1|2|1)

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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PH domain-like0Direct
EF-hand0Direct
KA1-like0Direct
WD40 repeat-like0Direct
L domain-like0Direct
ARM repeat0Direct
TAF(II)230 TBP-binding fragment0Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0Direct
DBL homology domain (DH-domain)0Direct
alpha-D-mannose-specific plant lectins0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
Regulator of G-protein signaling, RGS0Direct
MAST3 pre-PK domain-like0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
RNI-like0Direct
Ankyrin repeat0Direct
Polo-box domain0Direct
Spectrin repeat0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
NTF2-like0Direct
DEATH domain0Direct
Tricorn protease domain 20Direct
PDZ domain-like0Direct
Snake toxin-like0Direct
Penicillin-binding protein 2x (pbp-2x), c-terminal domain0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
L27 domain0Direct
Cysteine-rich domain0Direct
G protein-binding domain0Direct
RCC1/BLIP-II0Direct
HR1 repeat0Direct
Doublecortin (DC)0Direct
Protein kinase-like (PK-like)0Direct
Concanavalin A-like lectins/glucanases0.00000000000000377Direct
CAD & PB1 domains0.00000000000002342Direct
MIT domain0.0000000000007927Direct
SMAD/FHA domain0.000000000001123Direct
CRAL/TRIO domain0.000000000001465Direct
cAMP-binding domain-like0.000000000006902Direct
Myosin rod fragments0.00000000008977Direct
Ubiquitin-like0.0000000002786Direct
beta-sandwich domain of Sec23/240.0000000003885Direct
TPR-like0.0000002613Direct
GTPase activation domain, GAP0.0000004897Direct
UBA-like0.00000271Direct
Chaperone J-domain0.000003086Direct
HCP-like0.000004509Direct
Cyclin-like0.00002377Direct
SH3-domain0.00003455Direct
C-type lectin-like0.00005201Direct
SCOP hierarchy in SUPERFAMILY0.0001132Direct
PX domain0.0002854Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.001342Inherited
Bromodomain0.001914Inherited
SAM/Pointed domain0.005992Inherited
Immunoglobulin0.02447Inherited
Fibronectin type III0.1475Inherited
PYP-like sensor domain (PAS domain)0.915Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
alpha-D-mannose-specific plant lectins0Direct
Polygalacturonase inhibiting protein PGIP0Direct
RIO1-like kinases0Direct
LIM domain0Direct
Ssp2 C-terminal domain-like0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
Protein kinases, catalytic subunit0Direct
Myosin rod fragments0Direct
MAST3 pre-PK domain-like0Direct
L27 domain0Direct
Swapped Polo-box domain0Direct
Polo-box duplicated region0Direct
Calmodulin-like0Direct
Legume lectins0Direct
Doublecortin (DC)0Direct
beta-lactamase inhibitor protein-II, BLIP-II0Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0Direct
Ankyrin repeat0Direct
MHCK/EF2 kinase0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0Direct
HR1 repeat0Direct
alpha-ketoacid dehydrogenase kinase, C-terminal domain0Direct
Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A0Direct
TAF(II)230 TBP-binding fragment0Direct
Kinase associated domain 1, KA10Direct
RhoA-binding domain0Direct
DEATH domain, DD0Direct
Extracellular domain of cell surface receptors0Direct
Pleckstrin-homology domain (PH domain)0Direct
Cyclin0Direct
Spectrin repeat0Direct
Synaptotagmin-like (S variant)0Direct
DBL homology domain (DH-domain)0Direct
Regulator of G-protein signaling, RGS0Direct
PLC-like (P variant)0Direct
Ras-binding domain, RBD5.532e-16Direct
RWD domain0.00000000000004253Direct
PB1 domain0.00000000000005117Direct
MIT domain0.0000000000003396Direct
cAMP-binding domain0.000000000001583Direct
FHA domain0.000000000002195Direct
Regulator of chromosome condensation RCC10.000000000007734Direct
Motor proteins0.00000000009439Direct
Quinoprotein alcohol dehydrogenase-like0.000000001231Direct
WD40-repeat0.0000001361Direct
BCR-homology GTPase activation domain (BH-domain)0.0000005076Direct
Chaperone J-domain0.000003068Direct
PDZ domain0.000006263Direct
Sulfatase-modifying factor-like0.00001494Direct
Tetratricopeptide repeat (TPR)0.00004023Direct
SH3-domain0.00009838Direct
UBA domain0.0001517Direct
I set domains0.0002304Direct
PX domain0.0003633Direct
Bromodomain0.002137Inherited
Caspase recruitment domain, CARD0.002337Inherited
Flavin-binding PAS domain0.003677Inherited
Phoshoinositide 3-kinase (PI3K) helical domain0.1678Inherited
Fibronectin type III0.2002Inherited
Histidine kinase0.2846Inherited
SAM (sterile alpha motif) domain1Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Tricorn protease domain 20Direct
alpha-D-mannose-specific plant lectins0Direct
Cysteine-rich domain0Direct
EF-hand0Direct
G protein-binding domain0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
DEATH domain0Direct
Doublecortin (DC)0Direct
RNI-like0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
Protein kinase-like (PK-like)0Direct
KA1-like0Direct
MAST3 pre-PK domain-like0Direct
DBL homology domain (DH-domain)0Direct
A DNA-binding domain in eukaryotic transcription factors0Direct
PH domain-like0Direct
Regulator of G-protein signaling, RGS0Direct
RCC1/BLIP-II0Direct
NTF2-like0Direct
ARM repeat0Direct
TAF(II)230 TBP-binding fragment0Direct
Ankyrin repeat0Direct
L27 domain0Direct
Penicillin-binding protein 2x (pbp-2x), c-terminal domain0Direct
Polo-box domain0Direct
L domain-like0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
Snake toxin-like0Direct
HR1 repeat0Direct
PDZ domain-like0Direct
Spectrin repeat0Direct
WD40 repeat-like0Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0Direct
Concanavalin A-like lectins/glucanases0.000000000000002635Direct
CAD & PB1 domains0.00000000000001651Direct
MIT domain0.0000000000005678Direct
SMAD/FHA domain0.0000000000008056Direct
CRAL/TRIO domain0.000000000001053Direct
cAMP-binding domain-like0.000000000004984Direct
Myosin rod fragments0.00000000006589Direct
Ubiquitin-like0.0000000002059Direct
beta-sandwich domain of Sec23/240.0000000002873Direct
TPR-like0.0000002012Direct
GTPase activation domain, GAP0.0000003791Direct
UBA-like0.000002126Direct
Chaperone J-domain0.000002423Direct
HCP-like0.000003544Direct
Cyclin-like0.00001893Direct
SH3-domain0.0000276Direct
C-type lectin-like0.00004167Direct
PX domain0.0002322Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.00111Inherited
Bromodomain0.001591Inherited
SAM/Pointed domain0.005042Inherited
Immunoglobulin0.02096Inherited
Fibronectin type III0.1296Inherited
PYP-like sensor domain (PAS domain)0.8451Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56112,101288
  • 56112 - Protein kinase-like (PK-like)
  • 101288 - L27 domain
    		• 0Direct
    53850,56112
  • 53850 - Periplasmic binding protein-like II
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    55021,56112
  • 55021 - ACT-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
    		• 0Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
    		• 0Direct
    56112,54427
  • 56112 - Protein kinase-like (PK-like)
  • 54427 - NTF2-like
    		• 0Direct
    50044,56112
  • 50044 - SH3-domain
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    56112,47473
  • 56112 - Protein kinase-like (PK-like)
  • 47473 - EF-hand
    		• 0Direct
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
    		• 0Direct
    56112,52799
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    56112,50998
  • 56112 - Protein kinase-like (PK-like)
  • 50998 - Quinoprotein alcohol dehydrogenase-like
    		• 0Direct
    57889,49562
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
    		• 0Direct
    47212,56112
  • 47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
    		• 0Direct
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
    		• 0Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
    		• 0Direct
    47986,56112
  • 47986 - DEATH domain
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    56112,48403
  • 56112 - Protein kinase-like (PK-like)
  • 48403 - Ankyrin repeat
    		• 0Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
    		• 0Direct
    56112,50978
  • 56112 - Protein kinase-like (PK-like)
  • 50978 - WD40 repeat-like
    		• 0Direct
    52047,56112
  • 52047 - RNI-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    54277,57889
  • 54277 - CAD & PB1 domains
  • 57889 - Cysteine-rich domain
    		• 0Direct
    55073,56112
  • 55073 - Nucleotide cyclase
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    56112,116846
  • 56112 - Protein kinase-like (PK-like)
  • 116846 - MIT domain
    		• 0Direct
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
    		• 0Direct
    56112,48452
  • 56112 - Protein kinase-like (PK-like)
  • 48452 - TPR-like
    		• 0Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
    		• 0Direct
    56112,50729
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
    		• 0Direct
    51110,51110
  • 51110 - alpha-D-mannose-specific plant lectins
  • 51110 - alpha-D-mannose-specific plant lectins
    		• 0Direct
    49562,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    50729,69322
  • 50729 - PH domain-like
  • 69322 - Tricorn protease domain 2
    		• 0Direct
    101288,101288
  • 101288 - L27 domain
  • 101288 - L27 domain
    		• 0Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0Direct
    46585,49562
  • 46585 - HR1 repeat
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
    		• 0Direct
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
    		• 0Direct
    -9,-7
  • -9 - PDB
  • -7 - CATH
    		• 0Direct
    56112,50985
  • 56112 - Protein kinase-like (PK-like)
  • 50985 - RCC1/BLIP-II
    		• 0Direct
    53067,56112
  • 53067 - Actin-like ATPase domain
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    69012,55874
  • 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
    		• 0Direct
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
    		• 0Direct
    46785,56112
  • 46785 - "Winged helix" DNA-binding domain
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    56112,90257
  • 56112 - Protein kinase-like (PK-like)
  • 90257 - Myosin rod fragments
    		• 0Direct
    46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
    		• 0Direct
    50998,56112
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    116846,116846
  • 116846 - MIT domain
  • 116846 - MIT domain
    		• 0Direct
    49899,56112
  • 49899 - Concanavalin A-like lectins/glucanases
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
    		• 0Direct
    50156,56112
  • 50156 - PDZ domain-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    56112,54928
  • 56112 - Protein kinase-like (PK-like)
  • 54928 - RNA-binding domain, RBD
    		• 0Direct
    52087,46966
  • 52087 - CRAL/TRIO domain
  • 46966 - Spectrin repeat
    		• 0Direct
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
    		• 0Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
    		• 0Direct
    51206,56112
  • 51206 - cAMP-binding domain-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
    		• 0Direct
    81995,56112
  • 81995 - beta-sandwich domain of Sec23/24
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
    		• 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
    		• 0Direct
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0Direct
    52058,56112
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    56112,103243
  • 56112 - Protein kinase-like (PK-like)
  • 103243 - KA1-like
    		• 0Direct
    48097,56112
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    50044,48065
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
    		• 0Direct
    56112,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
    		• 0Direct
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
    		• 0Direct
    48726,56112
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    64268,56112
  • 64268 - PX domain
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
    		• 0Direct
    56112,55681
  • 56112 - Protein kinase-like (PK-like)
  • 55681 - Class II aaRS and biotin synthetases
    		• 0Direct
    48403,56112
  • 48403 - Ankyrin repeat
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
    		• 0Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
    		• 0.000000000000003506Direct
    49879,56112
  • 49879 - SMAD/FHA domain
  • 56112 - Protein kinase-like (PK-like)
    		• 0.0000000000004242Direct
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
    		• 0.0000000000007233Direct
    49265,56112
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
    		• 0.0000000000007552Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
    		• 0.00000000002334Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
    		• 0.000000006698Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
    		• 0.00000001183Direct
    -7,56112
  • -7 - CATH
  • 56112 - Protein kinase-like (PK-like)
    		• 0.000004908Direct
    48403,47769
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
    		• 0.00000552Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
    		• 0.000007771Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
    		• 0.00001078Direct
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
    		• 0.00002623Direct
    48403,52540
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0.00004757Direct
    56112,50044
  • 56112 - Protein kinase-like (PK-like)
  • 50044 - SH3-domain
    		• 0.000116Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
    		• 0.0001818Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
    		• 0.0007725Direct
    56112,52540
  • 56112 - Protein kinase-like (PK-like)
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0.001409Inherited
    53850,53850
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
    		• 0.01388Inherited
    57850,48371
  • 57850 - RING/U-box
  • 48371 - ARM repeat
    		• 0.01946Inherited
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
    		• 0.08866Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
    		• 0.4463Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52058,52047,52058
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52058 - L domain-like
    		• 0Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
    		• 0Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0Direct
    46585,46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
    		• 0Direct
    48097,56112,50729
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
    		• 0Direct
    50044,48065,50729
  • 50044 - SH3-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
    		• 0Direct
    57889,57889,49562
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
    		• 0Direct
    49265,56112,48726
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
    		• 0Direct
    57889,49562,56112
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
    		• 0Direct
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
    		• 0Direct
    57716,50156,56112
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
    		• 0Direct
    52058,52058,56112
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    53850,53850,56112
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    101288,101288,50156
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
    		• 0Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
    		• 0Direct
    48726,49265,56112
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    -9,-7,56112
  • -9 - PDB
  • -7 - CATH
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
    		• 0Direct
    52087,46966,46966
  • 52087 - CRAL/TRIO domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
    		• 0Direct
    52047,52047,52058
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 52058 - L domain-like
    		• 0Direct
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
    		• 0Direct
    51206,51206,56112
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    56112,101288,101288
  • 56112 - Protein kinase-like (PK-like)
  • 101288 - L27 domain
  • 101288 - L27 domain
    		• 0Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
    		• 0Direct
    56112,52799,49562
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
    		• 0Direct
    56112,116846,116846
  • 56112 - Protein kinase-like (PK-like)
  • 116846 - MIT domain
  • 116846 - MIT domain
    		• 0Direct
    52047,52058,56112
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    48726,48726,56112
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    56112,48726,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
    		• 0Direct
    56112,48403,52540
  • 56112 - Protein kinase-like (PK-like)
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0Direct
    52047,52047,56112
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0Direct
    57889,50729,69322
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 69322 - Tricorn protease domain 2
    		• 0Direct
    52058,52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52058 - L domain-like
    		• 0.000000000009925Direct
    52058,52047,56112
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 56112 - Protein kinase-like (PK-like)
    		• 0.0000000001983Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
    		• 0.00000009997Direct
    49265,48726,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
    		• 0.0000007051Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
    		• 0.07743Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
    		• 0.1502Inherited

    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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    Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

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    © Copyright 2017 The SUPERFAMILY authors and Julian Gough.