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Enzyme Commission (EC): Hydrolases
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: EC Hierarchy (from IntEnz release 70)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this EC term (SDEC level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Bacterial GAP domain | 0 | DIRECT |
| Rof/RNase P subunit-like | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| Xylose isomerase-like | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Cysteine proteinases | 0 | DIRECT |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | DIRECT |
| "Winged helix" DNA-binding domain | 0 | DIRECT |
| Sulfolobus fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| ComB-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| Urease, beta-subunit | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Plant lectins/antimicrobial peptides | 0 | DIRECT |
| Plant invertase/pectin methylesterase inhibitor | 0 | DIRECT |
| Type I dockerin domain | 0 | DIRECT |
| Voltage-gated potassium channels | 0 | DIRECT |
| Retrovirus capsid dimerization domain-like | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| SpoIIaa-like | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Peptidyl-tRNA hydrolase domain-like | 0 | DIRECT |
| Apyrase | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Hyaluronidase post-catalytic domain-like | 0 | DIRECT |
| C-terminal domain of Ku80 | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| Concanavalin A-like lectins/glucanases | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| Isochorismatase-like hydrolases | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| alpha/beta-Hydrolases | 0 | DIRECT |
| Methylesterase CheB, C-terminal domain | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| STI-like | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Lysozyme-like | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| Replicase NSP9 | 0 | DIRECT |
| CobE/GbiG C-terminal domain-like | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| Peptidyl-tRNA hydrolase-like | 0 | DIRECT |
| Invasin/intimin cell-adhesion fragments | 0 | DIRECT |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| Dcp2 domain-like | 0 | DIRECT |
| Sortase | 0 | DIRECT |
| Rnp2-like | 0 | DIRECT |
| Retroviral matrix proteins | 0 | DIRECT |
| Carbohydrate-binding domain | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| CbiG N-terminal domain-like | 0 | DIRECT |
| Ribosome inactivating proteins (RIP) | 0 | DIRECT |
| N-terminal domain of DnaB helicase | 0 | DIRECT |
| CheY-like | 0 | DIRECT |
| Glycosyl hydrolases family 6, cellulases | 0 | DIRECT |
| OMPT-like | 0 | DIRECT |
| Thermostable phytase (3-phytase) | 0 | DIRECT |
| Acylphosphatase/BLUF domain-like | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Peptidase/esterase 'gauge' domain | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| all-alpha NTP pyrophosphatases | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Ribonuclease H-like | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| SurE-like | 0 | DIRECT |
| Putative cyclase | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| (Trans)glycosidases | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| CinA-like | 0 | DIRECT |
| LmbE-like | 0 | DIRECT |
| Beta-galactosidase LacA, domain 3 | 0 | DIRECT |
| XseB-like | 0 | DIRECT |
| Cellulose-binding domain | 0 | DIRECT |
| DHH phosphoesterases | 0 | DIRECT |
| LigT-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| CYTH-like phosphatases | 0 | DIRECT |
| AbfB domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Peptidyl-tRNA hydrolase II | 0 | DIRECT |
| Trypsin-like serine proteases | 0 | DIRECT |
| Toll/Interleukin receptor TIR domain | 0 | DIRECT |
| DNA primase core | 0 | DIRECT |
| Sialidases | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| HisI-like | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| Transthyretin (synonym: prealbumin) | 0 | DIRECT |
| AlbA-like | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| Macro domain-like | 0 | DIRECT |
| Glutaminase/Asparaginase | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| Type X cellulose binding domain, CBDX | 0 | DIRECT |
| Viral protein domain | 0 | DIRECT |
| Nucleoside hydrolase | 0 | DIRECT |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | DIRECT |
| Putative isomerase YbhE | 0 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
| Coronavirus NSP10-like | 0 | DIRECT |
| Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Sec-C motif | 0 | DIRECT |
| Coronavirus NSP8-like | 0 | DIRECT |
| RibA-like | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Cellulose docking domain, dockering | 0 | DIRECT |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | DIRECT |
| CNF1/YfiH-like putative cysteine hydrolases | 0 | DIRECT |
| DTD-like | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| SEA domain | 0 | DIRECT |
| N-terminal domain of MutM-like DNA repair proteins | 0 | DIRECT |
| Rap30/74 interaction domains | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| HybD-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
| SARS Nsp1-like | 0 | DIRECT |
| Aminopeptidase/glucanase lid domain | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | DIRECT |
| Inorganic pyrophosphatase | 0 | DIRECT |
| L9 N-domain-like | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| EGF/Laminin | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| AF0625-like | 0 | DIRECT |
| Peptide deformylase | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| Nitrous oxide reductase, N-terminal domain | 0 | DIRECT |
| ssDNA viruses | 0 | DIRECT |
| Penicillin binding protein dimerisation domain | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Origin of replication-binding domain, RBD-like | 0 | DIRECT |
| Initiation factor IF2/eIF5b, domain 3 | 0 | DIRECT |
| Creatininase | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Phage fibre proteins | 0 | DIRECT |
| Saposin | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Toprim domain | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| Anthrax protective antigen | 0 | DIRECT |
| LD-carboxypeptidase A C-terminal domain-like | 0 | DIRECT |
| Collagen-binding domain | 0 | DIRECT |
| Phospholipase C/P1 nuclease | 0 | DIRECT |
| Dextranase, N-terminal domain | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| NSP3A-like | 0 | DIRECT |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | DIRECT |
| Kazal-type serine protease inhibitors | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| MCP/YpsA-like | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| Urease, gamma-subunit | 0 | DIRECT |
| Outer membrane phospholipase A (OMPLA) | 0 | DIRECT |
| Prokaryotic SH3-related domain | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| beta-N-acetylhexosaminidase-like domain | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| Coronavirus NSP7-like | 0 | DIRECT |
| Acetamidase/Formamidase-like | 0 | DIRECT |
| Penicillin-binding protein associated domain | 0 | DIRECT |
| TMV-like viral coat proteins | 0 | DIRECT |
| Metallo-dependent phosphatases | 0 | DIRECT |
| Arabinanase/levansucrase/invertase | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Archaeal IMP cyclohydrolase PurO | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| Holliday junction resolvase RusA | 0 | DIRECT |
| dUTPase-like | 0 | DIRECT |
| Galactose-binding domain-like | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | DIRECT |
| Influenza hemagglutinin (stalk) | 0 | DIRECT |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | DIRECT |
| Carbohydrate binding domain | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Herpes virus serine proteinase, assemblin | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| Autotransporter | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| E set domains | 2.574e-16 | DIRECT |
| HD-domain/PDEase-like | 2.574e-16 | DIRECT |
| vWA-like | 0.000000000000004014 | DIRECT |
| LysM domain | 0.00000000000003341 | DIRECT |
| Calcium-dependent phosphotriesterase | 0.00000000000004556 | DIRECT |
| EF-hand | 0.0000000000000605 | DIRECT |
| Translation proteins | 0.00000000000006195 | DIRECT |
| Microbial ribonucleases | 0.0000000000001068 | DIRECT |
| Purine and uridine phosphorylases | 0.0000000000003759 | DIRECT |
| EAL domain-like | 0.000000000000525 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0.000000000003233 | DIRECT |
| Tudor/PWWP/MBT | 0.00000000001922 | DIRECT |
| Phosphotyrosine protein phosphatases I | 0.00000000003059 | DIRECT |
| Staphylococcal nuclease | 0.0000000007822 | DIRECT |
| Ubiquitin-like | 0.0000000008392 | DIRECT |
| UBA-like | 0.000000002187 | DIRECT |
| DEATH domain | 0.0000000128 | DIRECT |
| PA domain | 0.00000001484 | DIRECT |
| Hairpin loop containing domain-like | 0.00000001644 | DIRECT |
| YjgF-like | 0.00000002395 | DIRECT |
| GAF domain-like | 0.00000003639 | DIRECT |
| LDL receptor-like module | 0.00000007491 | DIRECT |
| Phospholipase D/nuclease | 0.00000008644 | DIRECT |
| Fibronectin type III | 0.0000002887 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0.0000003763 | DIRECT |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.0000004054 | DIRECT |
| Starch-binding domain-like | 0.000001078 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0.00000174 | DIRECT |
| Phosphoglycerate mutase-like | 0.000004242 | DIRECT |
| beta-Roll | 0.000004884 | DIRECT |
| PUG domain-like | 0.000006756 | DIRECT |
| DNA clamp | 0.00002019 | DIRECT |
| CBD9-like | 0.00002019 | DIRECT |
| HCP-like | 0.000025 | DIRECT |
| HIT/MYND zinc finger-like | 0.00002946 | DIRECT |
| DEK C-terminal domain | 0.00002955 | DIRECT |
| PH0987 N-terminal domain-like | 0.00009805 | DIRECT |
| FnI-like domain | 0.0002467 | DIRECT |
| Chromo domain-like | 0.0003177 | DIRECT |
| Barwin-like endoglucanases | 0.0003483 | DIRECT |
| SRCR-like | 0.0008644 | DIRECT |
| Hedgehog/intein (Hint) domain | 0.001094 | INHERITED FROM: Exodeoxyribonucleases producing 5'-phosphomonoesters || DNA helicase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides || Exodeoxyribonuclease I |
| Ricin B-like lectins | 0.001753 | INHERITED FROM: Hydrolyzing N-glycosyl compounds || rRNA N-glycosylase || Glycosylases || Alpha-galactosidase |
| Cell wall binding repeat | 0.001772 | INHERITED FROM: N-acetylmuramoyl-L-alanine amidase || Glycosylases || In linear amides || Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds |
| WD40 repeat-like | 0.001984 | INHERITED FROM: Acting on ester bonds || Methylated diphthine methylhydrolase || Poly(A)-specific ribonuclease || Exoribonucleases producing 5'-phosphomonoesters |
| Ras GEF | 0.002281 | INHERITED FROM: Acting on ester bonds || Phosphoric diester hydrolases || Phosphoinositide phospholipase C |
| SAP domain | 0.002998 | INHERITED FROM: DNA helicase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides |
| Integrin alpha N-terminal domain | 0.004294 | INHERITED FROM: Acting on ester bonds || Phosphoric diester hydrolases || Glycosylphosphatidylinositol phospholipase D |
| GTPase activation domain, GAP | 0.004294 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Phosphoinositide 5-phosphatase || Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase || Inositol-polyphosphate 5-phosphatase |
| FAH | 0.006129 | INHERITED FROM: Acylpyruvate hydrolase || Acting on carbon-carbon bonds || Fumarylacetoacetase |
| PX domain | 0.007581 | INHERITED FROM: Acting on ester bonds || Phosphoric diester hydrolases || Phospholipase D |
| PIN domain-like | 0.008423 | INHERITED FROM: Acting on ester bonds || Endoribonucleases producing 5'-phosphomonoesters || Ribonuclease P || Exodeoxyribonuclease (lambda-induced) |
| F-box domain | 0.00926 | INHERITED FROM: DNA helicase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides |
| Rhodanese/Cell cycle control phosphatase | 0.01218 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Omega peptidases || Ubiquitinyl hydrolase 1 || Protein-serine/threonine phosphatase || Protein-tyrosine-phosphatase |
| C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase | 0.01415 | INHERITED FROM: Acting on ester bonds || 6-phosphogluconolactonase |
| RNA-binding domain, RBD | 0.01499 | INHERITED FROM: Poly(A)-specific ribonuclease || Phosphoinositide 5-phosphatase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides || RNA helicase || Exoribonucleases producing 5'-phosphomonoesters |
| Chaperone J-domain | 0.02284 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| MIT domain | 0.02305 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides || Vesicle-fusing ATPase |
| DNA-glycosylase | 0.02377 | INHERITED FROM: Hydrolyzing N-glycosyl compounds || Glycosylases || DNA-3-methyladenine glycosylase II || Adenine glycosylase |
| SCOP hierarchy in SUPERFAMILY | 0.02777 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides |
| Second domain of FERM | 0.03031 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Duplicated hybrid motif | 0.03372 | INHERITED FROM: Metalloendopeptidases || Lysostaphin || Acting on peptide bonds (peptidases) |
| PHP domain-like | 0.04797 | INHERITED FROM: Acting on ester bonds || Endoribonucleases producing 5'-phosphomonoesters || Histidinol-phosphatase || Ribonuclease P || 3',5'-nucleoside bisphosphate phosphatase |
| Homing endonucleases | 0.07904 | INHERITED FROM: DNA helicase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides |
| SMAD/FHA domain | 0.08389 | INHERITED FROM: Exodeoxyribonucleases producing 5'-phosphomonoesters || Acting on ester bonds || Adenosine-5'-diphospho-5'-(DNA) diphosphatase || Exodeoxyribonucleases producing 3'-phosphomonoesters || DNA-3'-diphospho-5'-guanosine diphosphatase |
| Ran binding protein zinc finger-like | 0.09462 | INHERITED FROM: Omega peptidases || Ubiquitinyl hydrolase 1 || Acting on peptide bonds (peptidases) |
| TATA-box binding protein-like | 0.1103 | INHERITED FROM: Hydrolyzing N-glycosyl compounds || Glycosylases || DNA-3-methyladenine glycosylase II |
| YrdC/RibB | 0.1146 | INHERITED FROM: GTP cyclohydrolase II || Acting on carbon-nitrogen bonds, other than peptide bonds || In cyclic amidines |
| CRAL/TRIO domain | 0.1536 | INHERITED FROM: Phosphoric monoester hydrolases || Protein-tyrosine-phosphatase |
| HMA, heavy metal-associated domain | 0.2483 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances || Acting on acid anhydrides |
| TRAF domain-like | 0.2483 | INHERITED FROM: Metalloendopeptidases || Meprin A || Omega peptidases || Meprin B || Ubiquitinyl hydrolase 1 || Acting on peptide bonds (peptidases) |
| NTF2-like | 0.2597 | INHERITED FROM: Phosphoric monoester hydrolases || RNA helicase || Sucrose-phosphate phosphatase |
| HSP20-like chaperones | 0.2812 | INHERITED FROM: Omega peptidases || Ubiquitinyl hydrolase 1 |
| Ankyrin repeat | 0.3555 | INHERITED FROM: Adenosinetriphosphatase || Phosphoric diester hydrolases || In linear amides || Glutaminase || 1-alkyl-2-acetylglycerophosphocholine esterase || NAD(+) diphosphatase || Lysophospholipase || Asparaginase |
| Non-globular alpha+beta subunits of globular proteins | 0.5869 | INHERITED FROM: Phosphoric monoester hydrolases || Protein-tyrosine-phosphatase |
| post-AAA+ oligomerization domain-like | 0.6337 | INHERITED FROM: Adenosinetriphosphatase || In phosphorus-containing anhydrides |
| PUA domain-like | 0.719 | INHERITED FROM: Serine endopeptidases || Acting on peptide bonds (peptidases) || Endopeptidase La |
| FYVE/PHD zinc finger | 0.7621 | INHERITED FROM: Phosphoric monoester hydrolases || Phosphatidylinositol-3,5-bisphosphate 3-phosphatase || DNA helicase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides || Protein-tyrosine-phosphatase || Phosphatidylinositol-3-phosphatase |
| ARM repeat | 0.7723 | INHERITED FROM: Ether hydrolases || ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase || Aminopeptidase B || Omega peptidases || Ubiquitinyl hydrolase 1 || Acting on ether bonds |
| Prokaryotic type I DNA topoisomerase | 0.8162 | INHERITED FROM: DNA helicase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides |
| Heme oxygenase-like | 0.8927 | INHERITED FROM: In other compounds || Aminopyrimidine aminohydrolase || Acting on carbon-nitrogen bonds, other than peptide bonds |
| Bromodomain | 0.9085 | INHERITED FROM: Adenosinetriphosphatase |
| Kelch motif | 0.9506 | INHERITED FROM: Phosphoric monoester hydrolases || Protein-serine/threonine phosphatase |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: Exoribonuclease II || Ribonuclease E || DNA helicase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides || Exoribonucleases producing 5'-phosphomonoesters |
| Thioredoxin-like | 1 | INHERITED FROM: Phospholipase A(2) |
| DHS-like NAD/FAD-binding domain | 1 | INHERITED FROM: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) || Acting on carbon-carbon bonds |
| Ribonuclease Rh-like | 1 | INHERITED FROM: Nucleoside-triphosphate phosphatase || Acting on ATP; involved in cellular and subcellular movement || Serine endopeptidases || Pestivirus NS3 polyprotein peptidase || RNA helicase || In phosphorus-containing anhydrides |
| Cupredoxins | 1 | INHERITED FROM: Protein-arginine deiminase || In linear amidines |
| L30e-like | 1 | INHERITED FROM: Endoribonucleases producing 5'-phosphomonoesters || Ribonuclease P |
| L domain-like | 1 | INHERITED FROM: Acting on ester bonds || Poly(A)-specific ribonuclease || Hydrolyzing N-glycosyl compounds || ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase || Exoribonucleases producing 5'-phosphomonoesters || Protein-serine/threonine phosphatase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| Terpenoid cyclases/Protein prenyltransferases | 1 | INHERITED FROM: Diphosphoric monoester hydrolases || Geranyl diphosphate diphosphatase |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | INHERITED FROM: Flavivirin || SARS coronavirus main proteinase || ADP-ribose 1''-phosphate phosphatase || Oleoyl-[acyl-carrier-protein] hydrolase || Nucleoside-triphosphate phosphatase || Endothelin-converting enzyme 1 || Polynucleotide 5'-phosphatase || RNA helicase |
| SH3-domain | 1 | INHERITED FROM: Phosphoric diester hydrolases || Phosphoinositide phospholipase C |
| LuxS/MPP-like metallohydrolase | 1 | INHERITED FROM: Pitrilysin || Metalloendopeptidases || Mitochondrial processing peptidase || Nardilysin || Insulysin || Acting on peptide bonds (peptidases) |
| Inosine monophosphate dehydrogenase (IMPDH) | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase |
| Acyl-CoA N-acyltransferases (Nat) | 1 | INHERITED FROM: Protein O-GlcNAcase |
| WW domain | 1 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || RNA helicase |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Glycerophosphocholine cholinephosphodiesterase || Phosphodiesterase I || Alkylglycerophosphoethanolamine phosphodiesterase || Acting on ester bonds || Bis(5'-adenosyl)-triphosphatase || Phosphoric diester hydrolases || Acting on carbon-phosphorus bonds || Phosphonoacetate hydrolase || Alkaline phosphatase || Sulfuric ester hydrolases || Nucleotide diphosphatase |
| Carbonic anhydrase | 1 | INHERITED FROM: Protein-tyrosine-phosphatase |
| Bet v1-like | 1 | INHERITED FROM: Acetyl-CoA hydrolase || Thiolester hydrolases |
| Calcium ATPase, transduction domain A | 1 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Calcium ATPase, transmembrane domain M | 1 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Growth factor receptor domain | 1 | INHERITED FROM: Coagulation factor Xa || Furin || Serine endopeptidases || Acting on peptide bonds (peptidases) |
| Phosphoenolpyruvate/pyruvate domain | 1 | INHERITED FROM: (3S)-malyl-CoA thioesterase |
| ACT-like | 1 | INHERITED FROM: Diphosphoric monoester hydrolases || Phosphoserine phosphatase || Formyltetrahydrofolate deformylase || Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase |
| Clavaminate synthase-like | 1 | INHERITED FROM: RNA helicase |
| beta-carbonic anhydrase, cab | 1 | INHERITED FROM: Acting on carbon-sulfur bonds || Carbon disulfide hydrolase |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: In other compounds || 1-aminocyclopropane-1-carboxylate deaminase |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | INHERITED FROM: 1,4-dihydroxy-2-naphthoyl-CoA hydrolase || Acting on ester bonds || Oleoyl-[acyl-carrier-protein] hydrolase || Palmitoyl-CoA hydrolase || Thiolester hydrolases |
| Cyclophilin-like | 1 | INHERITED FROM: In cyclic amides || 5-oxoprolinase (ATP-hydrolyzing) |
| Thiolase-like | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Acetyl-CoA hydrolase || Palmitoyl-CoA hydrolase || Thiolester hydrolases |
| Quinoprotein alcohol dehydrogenase-like | 1 | INHERITED FROM: Poly(A)-specific ribonuclease || Exoribonucleases producing 5'-phosphomonoesters |
| ADP-ribosylation | 1 | INHERITED FROM: NAD(+) glycohydrolase || Hydrolyzing N-glycosyl compounds |
| AraD/HMP-PK domain-like | 1 | INHERITED FROM: Acireductone synthase |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | INHERITED FROM: Adenosinetriphosphatase |
| Amidase signature (AS) enzymes | 1 | INHERITED FROM: In linear amides || Amidase || Fatty acid amide hydrolase || Allophanate hydrolase |
| FMT C-terminal domain-like | 1 | INHERITED FROM: DNA-3-methyladenine glycosylase II |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| PLP-dependent transferases | 1 | INHERITED FROM: Acting on carbon-carbon bonds || Kynureninase |
| ACP-like | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Ether hydrolases || Isochorismatase || Acting on ether bonds || Thiolester hydrolases |
| Nucleotidyltransferase | 1 | INHERITED FROM: Diphosphoric monoester hydrolases || Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase |
| Actin-like ATPase domain | 1 | INHERITED FROM: Adenosinetriphosphatase || Exopolyphosphatase || Guanosine-5'-triphosphate,3'-diphosphate diphosphatase || Non-chaperonin molecular chaperone ATPase || In phosphorus-containing anhydrides || UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) |
| TPR-like | 1 | INHERITED FROM: Protein-serine/threonine phosphatase |
| Immunoglobulin | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| PreATP-grasp domain | 1 | INHERITED FROM: Dihydroorotase |
| UDP-Glycosyltransferase/glycogen phosphorylase | 1 | INHERITED FROM: Trehalose-phosphatase || UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) |
| Formyltransferase | 1 | INHERITED FROM: Formyltetrahydrofolate deformylase |
| PHP14-like | 1 | INHERITED FROM: Acting on phosphorus-nitrogen bonds || Phosphohistidine phosphatase |
| SH2 domain | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Phosphoric diester hydrolases || Phosphoinositide 5-phosphatase || Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase || Inositol-polyphosphate 5-phosphatase || Phosphoinositide phospholipase C || Protein-tyrosine-phosphatase |
| Thiamin diphosphate-binding fold (THDP-binding) | 1 | INHERITED FROM: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) || Acting on carbon-carbon bonds |
| Dihydrofolate reductase-like | 1 | INHERITED FROM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase || Acting on carbon-nitrogen bonds, other than peptide bonds || In cyclic amidines |
| RmlC-like cupins | 1 | INHERITED FROM: (S)-ureidoglycine aminohydrolase |
| ADC-like | 1 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || Vesicle-fusing ATPase |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: Polynucleotide 5'-phosphatase |
| LDH C-terminal domain-like | 1 | INHERITED FROM: Alpha-galactosidase || Maltose-6'-phosphate glucosidase || Galacturonan 1,4-alpha-galacturonidase || 6-phospho-beta-glucosidase || Alpha-glucosidase |
| RING/U-box | 1 | INHERITED FROM: Omega peptidases || Ubiquitinyl hydrolase 1 |
| TGS-like | 1 | INHERITED FROM: Diphosphoric monoester hydrolases || Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Methenyltetrahydrofolate cyclohydrolase || Oleoyl-[acyl-carrier-protein] hydrolase || Thioether and trialkylsulfonium hydrolases || UDP-sulfoquinovose synthase || Maltose-6'-phosphate glucosidase || Acting on ether bonds || Acting on carbon-nitrogen bonds, other than peptide bonds || Alpha-N-acetylgalactosaminidase || In cyclic amidines |
| Periplasmic binding protein-like II | 1 | INHERITED FROM: Alkaline phosphatase |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Thiolester hydrolases |
| SAM/Pointed domain | 1 | INHERITED FROM: Hydrolyzing N-glycosyl compounds || ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase || Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase |
| Aspartate/ornithine carbamoyltransferase | 1 | INHERITED FROM: Dihydroorotase |
| GroES-like | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 1 | INHERITED FROM: Endodeoxyribonucleases producing 5'-phosphomonoesters || Deoxyribonuclease V |
| CCCH zinc finger | 1 | INHERITED FROM: RNA helicase |
| PYP-like sensor domain (PAS domain) | 1 | INHERITED FROM: Phosphoric diester hydrolases || 3',5'-cyclic-AMP phosphodiesterase || Cyclic-guanylate-specific phosphodiesterase |
| Nucleotide cyclase | 1 | INHERITED FROM: Phosphoric diester hydrolases || Cyclic-guanylate-specific phosphodiesterase |
| Terpenoid synthases | 1 | INHERITED FROM: Diphosphoric monoester hydrolases || Geranyl diphosphate diphosphatase |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Bacterial GAP domain | 0 | Direct |
| Rof/RNase P subunit-like | 0 | Direct |
| PH domain-like | 0 | Direct |
| Xylose isomerase-like | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
| PP2C-like | 0 | Direct |
| Cysteine proteinases | 0 | Direct |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | Direct |
| "Winged helix" DNA-binding domain | 0 | Direct |
| Sulfolobus fructose-1,6-bisphosphatase-like | 0 | Direct |
| ComB-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| (Phosphotyrosine protein) phosphatases II | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| Urease, beta-subunit | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Plant lectins/antimicrobial peptides | 0 | Direct |
| Plant invertase/pectin methylesterase inhibitor | 0 | Direct |
| Type I dockerin domain | 0 | Direct |
| Voltage-gated potassium channels | 0 | Direct |
| Retrovirus capsid dimerization domain-like | 0 | Direct |
| Kringle-like | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| DNase I-like | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| SpoIIaa-like | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Peptidyl-tRNA hydrolase domain-like | 0 | Direct |
| Apyrase | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Hyaluronidase post-catalytic domain-like | 0 | Direct |
| C-terminal domain of Ku80 | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| Concanavalin A-like lectins/glucanases | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| Isochorismatase-like hydrolases | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| alpha/beta-Hydrolases | 0 | Direct |
| Methylesterase CheB, C-terminal domain | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| STI-like | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Lysozyme-like | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| Replicase NSP9 | 0 | Direct |
| CobE/GbiG C-terminal domain-like | 0 | Direct |
| Nudix | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| Peptidyl-tRNA hydrolase-like | 0 | Direct |
| Invasin/intimin cell-adhesion fragments | 0 | Direct |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | Direct |
| EndoU-like | 0 | Direct |
| Dcp2 domain-like | 0 | Direct |
| Sortase | 0 | Direct |
| Rnp2-like | 0 | Direct |
| Retroviral matrix proteins | 0 | Direct |
| Carbohydrate-binding domain | 0 | Direct |
| Caspase-like | 0 | Direct |
| CbiG N-terminal domain-like | 0 | Direct |
| Ribosome inactivating proteins (RIP) | 0 | Direct |
| N-terminal domain of DnaB helicase | 0 | Direct |
| CheY-like | 0 | Direct |
| Glycosyl hydrolases family 6, cellulases | 0 | Direct |
| OMPT-like | 0 | Direct |
| Thermostable phytase (3-phytase) | 0 | Direct |
| Acylphosphatase/BLUF domain-like | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| Peptidase/esterase 'gauge' domain | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| all-alpha NTP pyrophosphatases | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| R3H domain | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| ITPase-like | 0 | Direct |
| HIT-like | 0 | Direct |
| HAD-like | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Ribonuclease H-like | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| SurE-like | 0 | Direct |
| Putative cyclase | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| (Trans)glycosidases | 0 | Direct |
| PKD domain | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| DUSP-like | 0 | Direct |
| CinA-like | 0 | Direct |
| LmbE-like | 0 | Direct |
| Beta-galactosidase LacA, domain 3 | 0 | Direct |
| XseB-like | 0 | Direct |
| Cellulose-binding domain | 0 | Direct |
| DHH phosphoesterases | 0 | Direct |
| LigT-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| CYTH-like phosphatases | 0 | Direct |
| AbfB domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Peptidyl-tRNA hydrolase II | 0 | Direct |
| Trypsin-like serine proteases | 0 | Direct |
| Toll/Interleukin receptor TIR domain | 0 | Direct |
| DNA primase core | 0 | Direct |
| Sialidases | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| HisI-like | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| Transthyretin (synonym: prealbumin) | 0 | Direct |
| AlbA-like | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| Acid proteases | 0 | Direct |
| Macro domain-like | 0 | Direct |
| Glutaminase/Asparaginase | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| Type X cellulose binding domain, CBDX | 0 | Direct |
| Viral protein domain | 0 | Direct |
| Nucleoside hydrolase | 0 | Direct |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | Direct |
| Putative isomerase YbhE | 0 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
| Coronavirus NSP10-like | 0 | Direct |
| Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Sec-C motif | 0 | Direct |
| Coronavirus NSP8-like | 0 | Direct |
| RibA-like | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Cellulose docking domain, dockering | 0 | Direct |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | Direct |
| CNF1/YfiH-like putative cysteine hydrolases | 0 | Direct |
| DTD-like | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| SEA domain | 0 | Direct |
| N-terminal domain of MutM-like DNA repair proteins | 0 | Direct |
| Rap30/74 interaction domains | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| HybD-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | Direct |
| GLA-domain | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
| SARS Nsp1-like | 0 | Direct |
| Aminopeptidase/glucanase lid domain | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | Direct |
| Inorganic pyrophosphatase | 0 | Direct |
| L9 N-domain-like | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| EGF/Laminin | 0 | Direct |
| HRDC-like | 0 | Direct |
| Trefoil | 0 | Direct |
| AF0625-like | 0 | Direct |
| Peptide deformylase | 0 | Direct |
| PAZ domain | 0 | Direct |
| Nitrous oxide reductase, N-terminal domain | 0 | Direct |
| ssDNA viruses | 0 | Direct |
| Penicillin binding protein dimerisation domain | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Origin of replication-binding domain, RBD-like | 0 | Direct |
| Initiation factor IF2/eIF5b, domain 3 | 0 | Direct |
| Creatininase | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Phage fibre proteins | 0 | Direct |
| Saposin | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Toprim domain | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| Anthrax protective antigen | 0 | Direct |
| LD-carboxypeptidase A C-terminal domain-like | 0 | Direct |
| Collagen-binding domain | 0 | Direct |
| Phospholipase C/P1 nuclease | 0 | Direct |
| Dextranase, N-terminal domain | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| NSP3A-like | 0 | Direct |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | Direct |
| Kazal-type serine protease inhibitors | 0 | Direct |
| Pentein | 0 | Direct |
| MCP/YpsA-like | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| Urease, gamma-subunit | 0 | Direct |
| Outer membrane phospholipase A (OMPLA) | 0 | Direct |
| Prokaryotic SH3-related domain | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| beta-N-acetylhexosaminidase-like domain | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| Coronavirus NSP7-like | 0 | Direct |
| Acetamidase/Formamidase-like | 0 | Direct |
| Penicillin-binding protein associated domain | 0 | Direct |
| TMV-like viral coat proteins | 0 | Direct |
| Metallo-dependent phosphatases | 0 | Direct |
| Arabinanase/levansucrase/invertase | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Archaeal IMP cyclohydrolase PurO | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| Holliday junction resolvase RusA | 0 | Direct |
| dUTPase-like | 0 | Direct |
| Galactose-binding domain-like | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | Direct |
| Influenza hemagglutinin (stalk) | 0 | Direct |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | Direct |
| Carbohydrate binding domain | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Herpes virus serine proteinase, assemblin | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| PGBD-like | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| BRK domain-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| beta-Galactosidase/glucuronidase domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| Autotransporter | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| E set domains | 2.574e-16 | Direct |
| HD-domain/PDEase-like | 2.574e-16 | Direct |
| vWA-like | 0.000000000000004014 | Direct |
| LysM domain | 0.00000000000003341 | Direct |
| Calcium-dependent phosphotriesterase | 0.00000000000004556 | Direct |
| EF-hand | 0.0000000000000605 | Direct |
| Translation proteins | 0.00000000000006195 | Direct |
| Microbial ribonucleases | 0.0000000000001068 | Direct |
| Purine and uridine phosphorylases | 0.0000000000003759 | Direct |
| EAL domain-like | 0.000000000000525 | Direct |
| Ribosomal protein S5 domain 2-like | 0.000000000003233 | Direct |
| Tudor/PWWP/MBT | 0.00000000001922 | Direct |
| Phosphotyrosine protein phosphatases I | 0.00000000003059 | Direct |
| Staphylococcal nuclease | 0.0000000007822 | Direct |
| Ubiquitin-like | 0.0000000008392 | Direct |
| UBA-like | 0.000000002187 | Direct |
| DEATH domain | 0.0000000128 | Direct |
| PA domain | 0.00000001484 | Direct |
| Hairpin loop containing domain-like | 0.00000001644 | Direct |
| YjgF-like | 0.00000002395 | Direct |
| GAF domain-like | 0.00000003639 | Direct |
| LDL receptor-like module | 0.00000007491 | Direct |
| Phospholipase D/nuclease | 0.00000008644 | Direct |
| Fibronectin type III | 0.0000002887 | Direct |
| NagB/RpiA/CoA transferase-like | 0.0000003763 | Direct |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.0000004054 | Direct |
| Starch-binding domain-like | 0.000001078 | Direct |
| N-(deoxy)ribosyltransferase-like | 0.00000174 | Direct |
| Phosphoglycerate mutase-like | 0.000004242 | Direct |
| beta-Roll | 0.000004884 | Direct |
| PUG domain-like | 0.000006756 | Direct |
| DNA clamp | 0.00002019 | Direct |
| CBD9-like | 0.00002019 | Direct |
| HCP-like | 0.000025 | Direct |
| HIT/MYND zinc finger-like | 0.00002946 | Direct |
| DEK C-terminal domain | 0.00002955 | Direct |
| PH0987 N-terminal domain-like | 0.00009805 | Direct |
| FnI-like domain | 0.0002467 | Direct |
| Chromo domain-like | 0.0003177 | Direct |
| Barwin-like endoglucanases | 0.0003483 | Direct |
| SRCR-like | 0.0008644 | Direct |
| Hedgehog/intein (Hint) domain | 0.001094 | Inherited |
| Ricin B-like lectins | 0.001753 | Inherited |
| Cell wall binding repeat | 0.001772 | Inherited |
| WD40 repeat-like | 0.001984 | Inherited |
| Ras GEF | 0.002281 | Inherited |
| SAP domain | 0.002998 | Inherited |
| Integrin alpha N-terminal domain | 0.004294 | Inherited |
| GTPase activation domain, GAP | 0.004294 | Inherited |
| FAH | 0.006129 | Inherited |
| PX domain | 0.007581 | Inherited |
| PIN domain-like | 0.008423 | Inherited |
| F-box domain | 0.00926 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.01218 | Inherited |
| C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase | 0.01415 | Inherited |
| RNA-binding domain, RBD | 0.01499 | Inherited |
| Chaperone J-domain | 0.02284 | Inherited |
| MIT domain | 0.02305 | Inherited |
| DNA-glycosylase | 0.02377 | Inherited |
| SCOP hierarchy in SUPERFAMILY | 0.02777 | Inherited |
| Second domain of FERM | 0.03031 | Inherited |
| Duplicated hybrid motif | 0.03372 | Inherited |
| PHP domain-like | 0.04797 | Inherited |
| Homing endonucleases | 0.07904 | Inherited |
| SMAD/FHA domain | 0.08389 | Inherited |
| Ran binding protein zinc finger-like | 0.09462 | Inherited |
| TATA-box binding protein-like | 0.1103 | Inherited |
| YrdC/RibB | 0.1146 | Inherited |
| CRAL/TRIO domain | 0.1536 | Inherited |
| HMA, heavy metal-associated domain | 0.2483 | Inherited |
| TRAF domain-like | 0.2483 | Inherited |
| NTF2-like | 0.2597 | Inherited |
| HSP20-like chaperones | 0.2812 | Inherited |
| Ankyrin repeat | 0.3555 | Inherited |
| Non-globular alpha+beta subunits of globular proteins | 0.5869 | Inherited |
| post-AAA+ oligomerization domain-like | 0.6337 | Inherited |
| PUA domain-like | 0.719 | Inherited |
| FYVE/PHD zinc finger | 0.7621 | Inherited |
| ARM repeat | 0.7723 | Inherited |
| Prokaryotic type I DNA topoisomerase | 0.8162 | Inherited |
| Heme oxygenase-like | 0.8927 | Inherited |
| Bromodomain | 0.9085 | Inherited |
| Kelch motif | 0.9506 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
| Thioredoxin-like | 1 | Inherited |
| DHS-like NAD/FAD-binding domain | 1 | Inherited |
| Ribonuclease Rh-like | 1 | Inherited |
| Cupredoxins | 1 | Inherited |
| L30e-like | 1 | Inherited |
| L domain-like | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| Terpenoid cyclases/Protein prenyltransferases | 1 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | Inherited |
| SH3-domain | 1 | Inherited |
| LuxS/MPP-like metallohydrolase | 1 | Inherited |
| Inosine monophosphate dehydrogenase (IMPDH) | 1 | Inherited |
| Acyl-CoA N-acyltransferases (Nat) | 1 | Inherited |
| WW domain | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| Carbonic anhydrase | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| Calcium ATPase, transduction domain A | 1 | Inherited |
| Calcium ATPase, transmembrane domain M | 1 | Inherited |
| Growth factor receptor domain | 1 | Inherited |
| Phosphoenolpyruvate/pyruvate domain | 1 | Inherited |
| ACT-like | 1 | Inherited |
| Clavaminate synthase-like | 1 | Inherited |
| beta-carbonic anhydrase, cab | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | Inherited |
| Cyclophilin-like | 1 | Inherited |
| Thiolase-like | 1 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 1 | Inherited |
| ADP-ribosylation | 1 | Inherited |
| AraD/HMP-PK domain-like | 1 | Inherited |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | Inherited |
| Amidase signature (AS) enzymes | 1 | Inherited |
| FMT C-terminal domain-like | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
| PLP-dependent transferases | 1 | Inherited |
| ACP-like | 1 | Inherited |
| Nucleotidyltransferase | 1 | Inherited |
| Actin-like ATPase domain | 1 | Inherited |
| TPR-like | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
| PreATP-grasp domain | 1 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 1 | Inherited |
| Formyltransferase | 1 | Inherited |
| PHP14-like | 1 | Inherited |
| SH2 domain | 1 | Inherited |
| Thiamin diphosphate-binding fold (THDP-binding) | 1 | Inherited |
| Dihydrofolate reductase-like | 1 | Inherited |
| RmlC-like cupins | 1 | Inherited |
| ADC-like | 1 | Inherited |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
| LDH C-terminal domain-like | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| TGS-like | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| Periplasmic binding protein-like II | 1 | Inherited |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | Inherited |
| SAM/Pointed domain | 1 | Inherited |
| Aspartate/ornithine carbamoyltransferase | 1 | Inherited |
| GroES-like | 1 | Inherited |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 1 | Inherited |
| CCCH zinc finger | 1 | Inherited |
| PYP-like sensor domain (PAS domain) | 1 | Inherited |
| Nucleotide cyclase | 1 | Inherited |
| Terpenoid synthases | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this EC term (SDEC level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Sphingomyelin phosphodiesterase-like | 0 | DIRECT |
| RecU-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Fibronectin type I module | 0 | DIRECT |
| ITPase (Ham1) | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| Alkaline phosphatase | 0 | DIRECT |
| Exodeoxyribonuclease V beta chain (RecB), C-terminal domain | 0 | DIRECT |
| HTLV-II matrix protein | 0 | DIRECT |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | DIRECT |
| Methylesterase CheB, C-terminal domain | 0 | DIRECT |
| tRNA splicing product Appr>p cyclic nucleotide phosphodiesterase | 0 | DIRECT |
| S-adenosylhomocystein hydrolase | 0 | DIRECT |
| Acyl-CoA thioesterase | 0 | DIRECT |
| M48USP-like | 0 | DIRECT |
| Tandem AAA-ATPase domain | 0 | DIRECT |
| ADPRibase-Mn-like | 0 | DIRECT |
| Plant invertase/pectin methylesterase inhibitor | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| alpha-mannosidase, domain 2 | 0 | DIRECT |
| Phospholipase C | 0 | DIRECT |
| Mismatch glycosylase | 0 | DIRECT |
| Carboxylesterase | 0 | DIRECT |
| YihX-like | 0 | DIRECT |
| Esterase | 0 | DIRECT |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Glycerophosphoryl diester phosphodiesterase | 0 | DIRECT |
| CBM22 | 0 | DIRECT |
| CDH-like | 0 | DIRECT |
| Lysophospholipase | 0 | DIRECT |
| Putative isomerase YbhE | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| Hypothetical esterase YJL068C | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Germination protease | 0 | DIRECT |
| Ppx/GppA phosphatase | 0 | DIRECT |
| CobE/GbiG C-terminal domain-like | 0 | DIRECT |
| alpha-Subunit of urease | 0 | DIRECT |
| Hyaluronidase N-terminal domain-like | 0 | DIRECT |
| DUSP, domain in ubiquitin-specific proteases | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| Phosphotriesterase-like | 0 | DIRECT |
| Dac-like | 0 | DIRECT |
| Insect phospholipase A2 | 0 | DIRECT |
| Thermolysin-like | 0 | DIRECT |
| RNase P subunit p30 | 0 | DIRECT |
| Glycosyl hydrolases family 32 N-terminal domain | 0 | DIRECT |
| Ribonuclease H | 0 | DIRECT |
| Galacturonase | 0 | DIRECT |
| Viral proteases | 0 | DIRECT |
| HAD-related | 0 | DIRECT |
| DTD-like | 0 | DIRECT |
| Arginine deiminase | 0 | DIRECT |
| GUCT domain | 0 | DIRECT |
| PepX catalytic domain-like | 0 | DIRECT |
| Dihydroorotase | 0 | DIRECT |
| RNase III catalytic domain-like | 0 | DIRECT |
| Alpha-toxin, C-terminal domain | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| Gastric lipase | 0 | DIRECT |
| Vertebrate phospholipase A2 | 0 | DIRECT |
| Glycosyl Hydrolase Family 88 | 0 | DIRECT |
| TNF-alpha converting enzyme, TACE, catalytic domain | 0 | DIRECT |
| LmbE-like | 0 | DIRECT |
| TMV-like viral coat proteins | 0 | DIRECT |
| Viral cysteine protease of trypsin fold | 0 | DIRECT |
| Zn metallo-beta-lactamase | 0 | DIRECT |
| HtrA-like serine proteases | 0 | DIRECT |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | DIRECT |
| CinA-like | 0 | DIRECT |
| Leukotriene A4 hydrolase catalytic domain | 0 | DIRECT |
| Elongation factors | 0 | DIRECT |
| AglA-like glucosidase | 0 | DIRECT |
| Fibronectin type II module | 0 | DIRECT |
| Proprotein convertase P-domain | 0 | DIRECT |
| Pancreatic carboxypeptidase, activation domain | 0 | DIRECT |
| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC | 0 | DIRECT |
| MtnX-like | 0 | DIRECT |
| Sulfolobus fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| Family 9 carbohydrate-binding module, CBD9 | 0 | DIRECT |
| Cellulose-binding domain family II | 0 | DIRECT |
| Cytidine deaminase | 0 | DIRECT |
| ATP-dependent protease Lon (La), catalytic domain | 0 | DIRECT |
| RecQ helicase DNA-binding domain-like | 0 | DIRECT |
| Phosphonoacetate hydrolase | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| mRNA decapping enzyme DcpS C-terminal domain | 0 | DIRECT |
| Papain-like | 0 | DIRECT |
| Peptidyl-tRNA hydrolase domain | 0 | DIRECT |
| Class B acid phosphatase, AphA | 0 | DIRECT |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | DIRECT |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | DIRECT |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | DIRECT |
| NSP3A-like | 0 | DIRECT |
| Glutaminase | 0 | DIRECT |
| Staphopain B, prodomain | 0 | DIRECT |
| Exodeoxyribonuclease V beta chain (RecC), C-terminal domain | 0 | DIRECT |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Peptide deformylase | 0 | DIRECT |
| Tail specific protease, catalytic domain | 0 | DIRECT |
| Apyrase | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Mason-Pfizer monkey virus matrix protein | 0 | DIRECT |
| C-terminal, Zn-finger domain of MutM-like DNA repair proteins | 0 | DIRECT |
| Glutaminase/Asparaginase | 0 | DIRECT |
| MutY C-terminal domain-like | 0 | DIRECT |
| MgsA/YrvN C-terminal domain-like | 0 | DIRECT |
| Shiga toxin, A-chain | 0 | DIRECT |
| Prohormone convertase 1 pro-domain | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| Arylsulfatase | 0 | DIRECT |
| Clostridium neurotoxins, C-terminal domain | 0 | DIRECT |
| Penicillin acylase, catalytic domain | 0 | DIRECT |
| Phosphoserine phosphatase | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Cutinase-like | 0 | DIRECT |
| Initiation factor IF2/eIF5b, domain 3 | 0 | DIRECT |
| Dextranase, N-terminal domain | 0 | DIRECT |
| SEA domain | 0 | DIRECT |
| alpha-L-arabinanase-like | 0 | DIRECT |
| Serralysin-like metalloprotease, catalytic (N-terminal) domain | 0 | DIRECT |
| Type 1 signal peptidase | 0 | DIRECT |
| Dimethylarginine dimethylaminohydrolase DDAH | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Biotin biosynthesis protein BioH | 0 | DIRECT |
| Fungal lipases | 0 | DIRECT |
| AF0625-like | 0 | DIRECT |
| Methionine aminopeptidase, insert domain | 0 | DIRECT |
| ADP ribosyl cyclase-like | 0 | DIRECT |
| DPP6 catalytic domain-like | 0 | DIRECT |
| Dual specificity phosphatase-like | 0 | DIRECT |
| Family 28 carbohydrate binding module, CBM28 | 0 | DIRECT |
| Predicted hydrolases Cof | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Purple acid phosphatase-like | 0 | DIRECT |
| MoCo carrier protein-like | 0 | DIRECT |
| Glycosyl hydrolases family 32 C-terminal domain | 0 | DIRECT |
| Alpha-L-arabinofuranosidase B, N-terminal domain | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| GRAM domain | 0 | DIRECT |
| Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF1 | 0 | DIRECT |
| FMDV leader protease | 0 | DIRECT |
| Hjc-like | 0 | DIRECT |
| Serine carboxypeptidase-like | 0 | DIRECT |
| Pancreatic carboxypeptidases | 0 | DIRECT |
| Transthyretin (synonym: prealbumin) | 0 | DIRECT |
| LamB/YcsF-like | 0 | DIRECT |
| Family 17 carbohydrate binding module, CBM17 | 0 | DIRECT |
| Z-DNA binding domain | 0 | DIRECT |
| Allantoicase repeat | 0 | DIRECT |
| RNA helicase | 0 | DIRECT |
| Janus/Ocnus | 0 | DIRECT |
| Sec63 C-terminal domain-like | 0 | DIRECT |
| D-aminoacylase, catalytic domain | 0 | DIRECT |
| Family 1 of glycosyl hydrolase | 0 | DIRECT |
| (Glycosyl)asparaginase | 0 | DIRECT |
| Amylase, catalytic domain | 0 | DIRECT |
| Putative alpha-L-fucosidase, catalytic domain | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| 2'-5' RNA ligase LigT | 0 | DIRECT |
| Type X cellulose binding domain, CBDX | 0 | DIRECT |
| Carboxypeptidase T | 0 | DIRECT |
| CBM11 | 0 | DIRECT |
| Dcp2 box A domain | 0 | DIRECT |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | DIRECT |
| NagD-like | 0 | DIRECT |
| Epoxide hydrolase | 0 | DIRECT |
| Deoxycytidylate deaminase-like | 0 | DIRECT |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | DIRECT |
| LexA-related | 0 | DIRECT |
| RuvC resolvase | 0 | DIRECT |
| Ku70 subunit middle domain | 0 | DIRECT |
| 1,4-beta-N-acetylmuraminidase | 0 | DIRECT |
| Sec63 N-terminal domain | 0 | DIRECT |
| Gamma-glutamyltranspeptidase-like | 0 | DIRECT |
| Nsp15 N-terminal domain-like | 0 | DIRECT |
| Retrovirus capsid protein C-terminal domain | 0 | DIRECT |
| Peptidyl-tRNA hydrolase II | 0 | DIRECT |
| beta-Galactosidase/glucuronidase, N-terminal domain | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| XseB-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| N-acetylglucosamine-6-phosphate deacetylase, NagA | 0 | DIRECT |
| Pepsin-like | 0 | DIRECT |
| EAL domain | 0 | DIRECT |
| Sialidases (neuraminidases) | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Plant cytotoxins | 0 | DIRECT |
| Archaeal IMP cyclohydrolase PurO | 0 | DIRECT |
| Isochorismatase-like hydrolases | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Coronavirus NSP7-like | 0 | DIRECT |
| LD-carboxypeptidase A N-terminal domain-like | 0 | DIRECT |
| DNA-binding domain from rap30 | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| Family 19 glycosidase | 0 | DIRECT |
| Ku70 subunit N-terminal domain | 0 | DIRECT |
| PUD-like | 0 | DIRECT |
| Pectin methylesterase | 0 | DIRECT |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | DIRECT |
| Outer membrane phospholipase A (OMPLA) | 0 | DIRECT |
| AbfB domain | 0 | DIRECT |
| mRNA triphosphatase CET1 | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF1 | 0 | DIRECT |
| GTP cyclohydrolase I | 0 | DIRECT |
| G-type lysozyme | 0 | DIRECT |
| Urease, gamma-subunit | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| PDEase | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase) | 0 | DIRECT |
| D-aminoacylase | 0 | DIRECT |
| Penta-EF-hand proteins | 0 | DIRECT |
| Carboxypeptidase regulatory domain | 0 | DIRECT |
| NPCBM-like | 0 | DIRECT |
| NagZ-like | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | DIRECT |
| SGL-like | 0 | DIRECT |
| Glycosyl hydrolases family 6, cellulases | 0 | DIRECT |
| C-terminal domain of Ku80 | 0 | DIRECT |
| Acyl-ACP thioesterase-like | 0 | DIRECT |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain | 0 | DIRECT |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | DIRECT |
| Hepsin, N-terminal domain | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| DEATH effector domain, DED | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| CbiG N-terminal domain-like | 0 | DIRECT |
| LON domain-like | 0 | DIRECT |
| Proline iminopeptidase-like | 0 | DIRECT |
| Replication initiation protein E1 | 0 | DIRECT |
| RNB domain-like | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| Arginase-like amidino hydrolases | 0 | DIRECT |
| Actin/HSP70 | 0 | DIRECT |
| YlbA-like | 0 | DIRECT |
| Gingipain R (RgpB), N-terminal domain | 0 | DIRECT |
| DNA/RNA non-specific endonuclease | 0 | DIRECT |
| Leucine aminopeptidase (Aminopeptidase A), N-terminal domain | 0 | DIRECT |
| Chitosanase | 0 | DIRECT |
| Bee venom hyaluronidase | 0 | DIRECT |
| Thioesterases | 0 | DIRECT |
| Class II viral fusion proteins C-terminal domain | 0 | DIRECT |
| Cdc48 N-terminal domain-like | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| Integrin alpha N-terminal domain | 0 | DIRECT |
| Enolase-phosphatase E1 | 0 | DIRECT |
| HRDC domain from helicases | 0 | DIRECT |
| SARS Nsp1-like | 0 | DIRECT |
| RNase P subunit p29-like | 0 | DIRECT |
| Serine-carboxyl proteinase, SCP | 0 | DIRECT |
| Eukaryotic proteases | 0 | DIRECT |
| LexA repressor, N-terminal DNA-binding domain | 0 | DIRECT |
| Influenza hemagglutinin (stalk) | 0 | DIRECT |
| Cytosine deaminase catalytic domain | 0 | DIRECT |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Peptidoglycan binding domain, PGBD | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| Caspase catalytic domain | 0 | DIRECT |
| N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain | 0 | DIRECT |
| Dextranase, catalytic domain | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| Carbon-carbon bond hydrolase | 0 | DIRECT |
| Virulence factor P.69 pertactin | 0 | DIRECT |
| Immunodeficiency virus matrix proteins | 0 | DIRECT |
| N-terminal domain of MutM-like DNA repair proteins | 0 | DIRECT |
| Matrix metalloproteases, catalytic domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| alpha-mannosidase, C-terminal domain | 0 | DIRECT |
| SAH/MTA deaminase-like | 0 | DIRECT |
| beta-N-acetylhexosaminidase catalytic domain | 0 | DIRECT |
| Caliciviridae-like VP | 0 | DIRECT |
| NodB-like polysaccharide deacetylase | 0 | DIRECT |
| Toll/Interleukin receptor TIR domain | 0 | DIRECT |
| GlpX-like bacterial fructose-1,6-bisphosphatase | 0 | DIRECT |
| RibA-like | 0 | DIRECT |
| Trehalose-phosphatase | 0 | DIRECT |
| Leishmanolysin | 0 | DIRECT |
| Prolyl oligopeptidase, N-terminal domain | 0 | DIRECT |
| Outer membrane protease OMPT | 0 | DIRECT |
| Pancreatic lipase, N-terminal domain | 0 | DIRECT |
| Trypanosoma sialidase, C-terminal domain | 0 | DIRECT |
| PBP5 C-terminal domain-like | 0 | DIRECT |
| Nsp15 C-terminal domain-like | 0 | DIRECT |
| Coronavirus NSP10-like | 0 | DIRECT |
| Aminopeptidase/glucanase lid domain | 0 | DIRECT |
| G proteins | 0 | DIRECT |
| Adenain-like | 0 | DIRECT |
| NADH pyrophosphatase | 0 | DIRECT |
| alpha-subunit of urease, catalytic domain | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| LD-carboxypeptidase A C-terminal domain-like | 0 | DIRECT |
| Bacterial dinuclear zinc exopeptidases | 0 | DIRECT |
| beta-glycanases | 0 | DIRECT |
| Endonuclease I | 0 | DIRECT |
| beta-Lactamase/D-ala carboxypeptidase | 0 | DIRECT |
| Glycosyl hydrolase family 7 catalytic core | 0 | DIRECT |
| HisI-like | 0 | DIRECT |
| Clostridium neurotoxins, catalytic domain | 0 | DIRECT |
| Putative serine hydrolase Ydr428c | 0 | DIRECT |
| Gingipain R (RgpB), C-terminal domain | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| CAF1-like ribonuclease | 0 | DIRECT |
| DNA helicase RuvA subunit, middle domain | 0 | DIRECT |
| alpha-mannosidase | 0 | DIRECT |
| Achaeal helicase C-terminal domain | 0 | DIRECT |
| beta-Galactosidase, domain 5 | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Leucine aminopeptidase, C-terminal domain | 0 | DIRECT |
| Putative acetylxylan esterase-like | 0 | DIRECT |
| Putative glucosidase YicI, domain 3 | 0 | DIRECT |
| NagB-like | 0 | DIRECT |
| NlpC/P60 | 0 | DIRECT |
| RNase Z-like | 0 | DIRECT |
| Zinc protease | 0 | DIRECT |
| MutT-like | 0 | DIRECT |
| GAG polyprotein M-domain | 0 | DIRECT |
| NTF2-like | 0 | DIRECT |
| MMP N-terminal domain | 0 | DIRECT |
| Nuclease | 0 | DIRECT |
| 3-methyladenine DNA glycosylase (AAG, ANPG, MPG) | 0 | DIRECT |
| Invasin/intimin cell-adhesion fragments | 0 | DIRECT |
| Retroviral integrase, catalytic domain | 0 | DIRECT |
| Helicase-like "domain" of reverse gyrase | 0 | DIRECT |
| YicI catalytic domain-like | 0 | DIRECT |
| Extended PAW domain | 0 | DIRECT |
| MMLV matrix protein-like | 0 | DIRECT |
| Acetylcholinesterase-like | 0 | DIRECT |
| Uracil-DNA glycosylase | 0 | DIRECT |
| Hyaluronidase post-catalytic domain-like | 0 | DIRECT |
| AstE/AspA-like | 0 | DIRECT |
| RNase P protein | 0 | DIRECT |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | DIRECT |
| Holliday junction resolvase RusA | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| Bacterial lipase | 0 | DIRECT |
| beta-N-acetylhexosaminidase domain | 0 | DIRECT |
| Nodaviridae-like VP | 0 | DIRECT |
| Proteasome subunits | 0 | DIRECT |
| beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
| alpha-D-glucuronidase/Hyaluronidase catalytic domain | 0 | DIRECT |
| Coronavirus NSP8-like | 0 | DIRECT |
| mRNA decapping enzyme-like | 0 | DIRECT |
| P1 nuclease | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| Clp protease, ClpP subunit | 0 | DIRECT |
| EGF-type module | 0 | DIRECT |
| Fungal zinc peptidase | 0 | DIRECT |
| Putative cyclase | 0 | DIRECT |
| Integrin A (or I) domain | 0 | DIRECT |
| Histidinol phosphatase-like | 0 | DIRECT |
| Trehalase-like | 0 | DIRECT |
| Carbohydrate binding domain | 0 | DIRECT |
| Adenosine/AMP deaminase | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
| Ppx associated domain | 0 | DIRECT |
| Ku80 subunit middle domain | 0 | DIRECT |
| Creatininase | 0 | DIRECT |
| GW domain | 0 | DIRECT |
| D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
| Patatin | 0 | DIRECT |
| CheY-related | 0 | DIRECT |
| GpdQ-like | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| Endonuclease IV | 0 | DIRECT |
| beta-Phosphoglucomutase-like | 0 | DIRECT |
| Herpes virus serine proteinase, assemblin | 0 | DIRECT |
| SurE-like | 0 | DIRECT |
| Imidazolonepropionase-like | 0 | DIRECT |
| Sortase | 0 | DIRECT |
| Carbamilase | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| 4HBT-like | 0 | DIRECT |
| Clostridium neurotoxins, the second last domain | 0 | DIRECT |
| Neutral endopeptidase (neprilysin) | 0 | DIRECT |
| Staphylococcal nuclease | 0 | DIRECT |
| Succinylarginine dihydrolase-like | 0 | DIRECT |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | DIRECT |
| Phosphonoacetaldehyde hydrolase-like | 0 | DIRECT |
| Beta-galactosidase LacA, domain 2 | 0 | DIRECT |
| Peptidyl-tRNA hydrolase-like | 0 | DIRECT |
| Mammalian PLC | 0 | DIRECT |
| Porphyromonas-type peptidylarginine deiminase | 0 | DIRECT |
| MazG-like | 0 | DIRECT |
| AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Xylanase/endoglucanase 11/12 | 0 | DIRECT |
| Myotubularin-like phosphatases | 0 | DIRECT |
| RecG "wedge" domain | 0 | DIRECT |
| Cellulose-binding domain | 0 | DIRECT |
| Macro domain | 0 | DIRECT |
| Beta-galactosidase LacA, domain 3 | 0 | DIRECT |
| Renal dipeptidase | 0 | DIRECT |
| Cellulases catalytic domain | 0 | DIRECT |
| Phage lysozyme | 0 | DIRECT |
| DNA helicase RuvA subunit, N-terminal domain | 0 | DIRECT |
| YicI N-terminal domain-like | 0 | DIRECT |
| Sec-C motif | 0 | DIRECT |
| C-type lysozyme | 0 | DIRECT |
| Helicase DNA-binding domain | 0 | DIRECT |
| SAH/MTA deaminase-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| PepX C-terminal domain-like | 0 | DIRECT |
| Astacin | 0 | DIRECT |
| Inosicase | 0 | DIRECT |
| Reverse transcriptase | 0 | DIRECT |
| PA1517-like | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| 2',3'-cyclic nucleotide 3'-phosphodiesterase, catalytic domain | 0 | DIRECT |
| RNase D C-terminal domains | 0 | DIRECT |
| Cellulose-binding domain family III | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Type II chitinase | 0 | DIRECT |
| Ubiquitin thiolesterase protein OTUB2 (Otubain-2) | 0 | DIRECT |
| Urease, beta-subunit | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| FolH catalytic domain-like | 0 | DIRECT |
| Rap30/74 interaction domains | 0 | DIRECT |
| Rpp14/Pop5-like | 0 | DIRECT |
| VanX-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| Toprim domain | 0 | DIRECT |
| alpha-D-glucuronidase, N-terminal domain | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| Composite domain of glycosyl hydrolase families 5, 30, 39 and 51 | 0 | DIRECT |
| Mug-like | 0 | DIRECT |
| Colipase-binding domain | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| Maf-like | 0 | DIRECT |
| Retroviral protease (retropepsin) | 0 | DIRECT |
| Acetamidase/Formamidase-like | 0 | DIRECT |
| Eng V-like | 0 | DIRECT |
| Leukotriene A4 hydrolase C-terminal domain | 0 | DIRECT |
| N-terminal domain of DnaB helicase | 0 | DIRECT |
| Type 2 phosphatidic acid phosphatase, PAP2 | 0 | DIRECT |
| mRNA cap methylase | 0 | DIRECT |
| Bacterial ribonucleases | 0 | DIRECT |
| Type I dockerin domain | 0 | DIRECT |
| Glycosyl hydrolases family 35 catalytic domain | 0 | DIRECT |
| Inorganic pyrophosphatase | 0 | DIRECT |
| Collagen-binding domain | 0 | DIRECT |
| RNA-dependent RNA-polymerase | 0 | DIRECT |
| CBM4/9 | 0 | DIRECT |
| Acylphosphatase-like | 0 | DIRECT |
| MPP-like | 0 | DIRECT |
| Pyrimidine 5'-nucleotidase (UMPH-1) | 0 | DIRECT |
| TIP49 domain | 0 | DIRECT |
| CheD-like | 0 | DIRECT |
| Subtilase propeptides/inhibitors | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| Neurolysin-like | 0 | DIRECT |
| ComB-like | 0 | DIRECT |
| Imidazolonepropionase-like | 0 | DIRECT |
| Parvoviridae-like VP | 0 | DIRECT |
| Bacterial chitobiase, n-terminal domain | 0 | DIRECT |
| N-terminal domain of RNase HI | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| Bacterial GAP domain | 0 | DIRECT |
| Prokaryotic proteases | 0 | DIRECT |
| Glucoamylase | 0 | DIRECT |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | DIRECT |
| TAP-like | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| dUTPase-like | 0 | DIRECT |
| Extended AAA-ATPase domain | 0 | DIRECT |
| A4 beta-galactosidase middle domain | 0 | DIRECT |
| Dienelactone hydrolase | 0 | DIRECT |
| Nitrilase | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| YdjC-like | 0 | DIRECT |
| Prolyl oligopeptidase, C-terminal domain | 0 | DIRECT |
| cAMP-binding domain | 0 | DIRECT |
| Ku80 subunit N-terminal domain | 0 | DIRECT |
| HisE-like (PRA-PH) | 0 | DIRECT |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| Penicillin binding protein dimerisation domain | 0 | DIRECT |
| Middle domain of MutM-like DNA repair proteins | 0 | DIRECT |
| EF-G/eEF-2 domains III and V | 0 | DIRECT |
| Replicase NSP9 | 0 | DIRECT |
| Manganese-dependent inorganic pyrophosphatase (family II) | 0 | DIRECT |
| Magnesium-dependent phosphatase-1, Mdp1 | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Beta-D-xylosidase C-terminal domain-like | 0 | DIRECT |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | DIRECT |
| Cellulose docking domain, dockering | 0 | DIRECT |
| Hevein-like agglutinin (lectin) domain | 0 | DIRECT |
| Thermostable phytase (3-phytase) | 0 | DIRECT |
| 5' nucleotidase-like | 0 | DIRECT |
| Nucleoside hydrolase | 0 | DIRECT |
| Virulence effector SptP domain | 0 | DIRECT |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
| Aspartyl dipeptidase PepE | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| NLI interacting factor-like phosphatase | 0 | DIRECT |
| Beta-galactosidase LacA, domains 4 and 5 | 0 | DIRECT |
| Kringle modules | 0 | DIRECT |
| HD domain | 3.693e-16 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 3.693e-16 | DIRECT |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0.000000000000002732 | DIRECT |
| MAM domain | 0.000000000000004356 | DIRECT |
| PA domain | 0.000000000000005436 | DIRECT |
| LysM domain | 0.00000000000003329 | DIRECT |
| DJ-1/PfpI | 0.00000000000008783 | DIRECT |
| EF-hand modules in multidomain proteins | 0.0000000000001042 | DIRECT |
| Haloalkane dehalogenase | 0.0000000000006696 | DIRECT |
| Purine and uridine phosphorylases | 0.000000000002011 | DIRECT |
| Nitrous oxide reductase, N-terminal domain | 0.000000000002366 | DIRECT |
| GAF domain | 0.00000000001962 | DIRECT |
| Caspase recruitment domain, CARD | 0.00000000002198 | DIRECT |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0.0000000002793 | DIRECT |
| Fungal ribonucleases | 0.0000000002793 | DIRECT |
| YjgF/L-PSP | 0.0000000007256 | DIRECT |
| Low-molecular-weight phosphotyrosine protein phosphatases | 0.0000000007361 | DIRECT |
| Tudor domain | 0.000000004515 | DIRECT |
| 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB | 0.000000007392 | DIRECT |
| Chromo domain | 0.000000008821 | DIRECT |
| LDL receptor-like module | 0.00000006839 | DIRECT |
| HCP-like | 0.0000001569 | DIRECT |
| TENA/THI-4 | 0.0000002849 | DIRECT |
| CYTH domain | 0.0000003816 | DIRECT |
| Starch-binding domain | 0.000000396 | DIRECT |
| Fibronectin type III | 0.0000003997 | DIRECT |
| Acetylhydrolase | 0.0000007617 | DIRECT |
| Peptidoglycan hydrolase LytM | 0.0000007617 | DIRECT |
| Ubiquitin-related | 0.000003163 | DIRECT |
| Serralysin-like metalloprotease, C-terminal domain | 0.000004648 | DIRECT |
| Glycosyl hydrolases family 16 | 0.00000596 | DIRECT |
| PUG domain | 0.000006062 | DIRECT |
| phosphatase domain of polynucleotide kinase | 0.00001784 | DIRECT |
| UBA domain | 0.00001997 | DIRECT |
| MATH domain | 0.00003045 | DIRECT |
| Pleckstrin-homology domain (PH domain) | 0.00003228 | DIRECT |
| PH0987 C-terminal domain-like | 0.00008657 | DIRECT |
| E-set domains of sugar-utilizing enzymes | 0.0001124 | DIRECT |
| Family 6 carbohydrate binding module, CBM6 | 0.0001147 | DIRECT |
| MYND zinc finger | 0.0001147 | DIRECT |
| Transglutaminase core | 0.0002342 | DIRECT |
| RibD C-terminal domain-like | 0.0003243 | DIRECT |
| PH0987 N-terminal domain-like | 0.0004187 | DIRECT |
| PaaI/YdiI-like | 0.0004187 | DIRECT |
| DEK C-terminal domain | 0.0004886 | DIRECT |
| 4-alpha-glucanotransferase, N-terminal domain | 0.0004886 | DIRECT |
| Acyl-carrier protein (ACP) | 0.0004886 | DIRECT |
| Third domain of FERM | 0.0005077 | DIRECT |
| Cell wall binding repeat | 0.001633 | INHERITED FROM: N-acetylmuramoyl-L-alanine amidase || Glycosylases || In linear amides || Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds |
| Anthrax toxin lethal factor, N- and C-terminal domains | 0.002032 | INHERITED FROM: Metalloendopeptidases || Acting on peptide bonds (peptidases) |
| GS domain | 0.002032 | INHERITED FROM: Omega peptidases || Ubiquitinyl hydrolase 1 || Acting on peptide bonds (peptidases) |
| Galactose-binding domain | 0.002046 | INHERITED FROM: Glycosylases || Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds |
| 4-alpha-glucanotransferase, domain 2 | 0.002046 | INHERITED FROM: Glycosylases || Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds || Alpha-amylase |
| 4-alpha-glucanotransferase, C-terminal domain | 0.002046 | INHERITED FROM: Glycosylases || Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds || Alpha-amylase |
| Ras GEF | 0.002046 | INHERITED FROM: Acting on ester bonds || Phosphoric diester hydrolases || Phosphoinositide phospholipase C |
| DNase I-like | 0.002119 | INHERITED FROM: Exodeoxyribonucleases producing 5'-phosphomonoesters || Endodeoxyribonucleases producing 5'-phosphomonoesters || Acting on ester bonds || Deoxyribonuclease I || Exodeoxyribonuclease III |
| SAP domain | 0.002868 | INHERITED FROM: DNA helicase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides |
| DNA repair glycosylase, 2 C-terminal domains | 0.003104 | INHERITED FROM: Hydrolyzing N-glycosyl compounds || Glycosylases || DNA-3-methyladenine glycosylase II |
| First domain of FERM | 0.003289 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| BCR-homology GTPase activation domain (BH-domain) | 0.003906 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Phosphoinositide 5-phosphatase || Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase || Inositol-polyphosphate 5-phosphatase |
| DnaQ-like 3'-5' exonuclease | 0.004738 | INHERITED FROM: Exodeoxyribonucleases producing 5'-phosphomonoesters || Acting on ester bonds || Poly(A)-specific ribonuclease || Exodeoxyribonuclease III || Ribonuclease H || Exoribonucleases producing 5'-phosphomonoesters || Exodeoxyribonuclease I || Ribonuclease D |
| Ricin B-like | 0.004833 | INHERITED FROM: Hydrolyzing N-glycosyl compounds || rRNA N-glycosylase || Glycosylases || Alpha-galactosidase |
| FAH | 0.004845 | INHERITED FROM: Acylpyruvate hydrolase || Acting on carbon-carbon bonds || Fumarylacetoacetase |
| Probable phosphatase YrbI | 0.005439 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || 3-deoxy-manno-octulosonate-8-phosphatase |
| Hydroxynitrile lyase-like | 0.008335 | INHERITED FROM: Carboxylic ester hydrolases || Acting on ester bonds |
| F-box domain | 0.008335 | INHERITED FROM: DNA helicase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides |
| MIT domain | 0.01143 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides || Vesicle-fusing ATPase |
| Intein (protein splicing domain) | 0.0189 | INHERITED FROM: DNA helicase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides |
| Chaperone J-domain | 0.02077 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Glycosyltransferase family 36 C-terminal domain | 0.02187 | INHERITED FROM: Alpha,alpha-trehalase || Glycosylases || Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds || Protein-glucosylgalactosylhydroxylysine glucosidase |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.02246 | INHERITED FROM: Acting on ester bonds || Oleoyl-[acyl-carrier-protein] hydrolase || Thiolester hydrolases |
| Second domain of FERM | 0.02325 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Leucine rich effector protein YopM | 0.02398 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-serine/threonine phosphatase |
| PX domain | 0.034 | INHERITED FROM: Acting on ester bonds || Phosphoric diester hydrolases || Phospholipase D |
| PHP domain | 0.04841 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Histidinol-phosphatase || 3',5'-nucleoside bisphosphate phosphatase |
| Haloperoxidase | 0.06732 | INHERITED FROM: Carboxylic ester hydrolases || Acting on ester bonds |
| UDP-N-acetylglucosamine 2-epimerase | 0.06838 | INHERITED FROM: Glycosylases || Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds || UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) |
| Canonical RBD | 0.08217 | INHERITED FROM: Acting on ester bonds || Poly(A)-specific ribonuclease || Phosphoinositide 5-phosphatase || RNA helicase || Exoribonucleases producing 5'-phosphomonoesters |
| MaoC-like | 0.08659 | INHERITED FROM: Acting on ester bonds || Oleoyl-[acyl-carrier-protein] hydrolase || Thiolester hydrolases |
| PDZ domain | 0.08659 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Ran binding protein zinc finger-like | 0.08942 | INHERITED FROM: Omega peptidases || Ubiquitinyl hydrolase 1 || Acting on peptide bonds (peptidases) |
| FHA domain | 0.0958 | INHERITED FROM: Exodeoxyribonucleases producing 5'-phosphomonoesters || Acting on ester bonds || Adenosine-5'-diphospho-5'-(DNA) diphosphatase || Exodeoxyribonucleases producing 3'-phosphomonoesters |
| DNA repair glycosylase, N-terminal domain | 0.1015 | INHERITED FROM: Hydrolyzing N-glycosyl compounds || Glycosylases || DNA-3-methyladenine glycosylase II |
| mRNA capping enzyme | 0.1532 | INHERITED FROM: Phosphoric monoester hydrolases || Polynucleotide 5'-phosphatase |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.1565 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Phosphatidylinositol-3,5-bisphosphate 3-phosphatase || Protein-tyrosine-phosphatase || Phosphatidylinositol-3-phosphatase |
| RelA/SpoT domain | 0.1849 | INHERITED FROM: Diphosphoric monoester hydrolases || Acting on ester bonds || Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase |
| Scavenger receptor cysteine-rich (SRCR) domain | 0.1918 | INHERITED FROM: Serine endopeptidases || Acting on peptide bonds (peptidases) || Complement factor I |
| PP1699/LP2961-like | 0.1925 | INHERITED FROM: Carboxylic ester hydrolases |
| CoA transferase alpha subunit-like | 0.2421 | INHERITED FROM: Acting on ester bonds || Acetyl-CoA hydrolase || Thiolester hydrolases |
| HMA, heavy metal-associated domain | 0.2437 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances || Acting on acid anhydrides |
| AlkB-like | 0.2792 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides || RNA helicase |
| PBP transglycosylase domain-like | 0.2821 | INHERITED FROM: Serine-type carboxypeptidases || Serine-type D-Ala-D-Ala carboxypeptidase || Acting on peptide bonds (peptidases) |
| Ankyrin repeat | 0.3277 | INHERITED FROM: Adenosinetriphosphatase || Phosphoric diester hydrolases || In linear amides || Glutaminase || 1-alkyl-2-acetylglycerophosphocholine esterase || NAD(+) diphosphatase || Lysophospholipase || Asparaginase |
| Ecto-ART | 0.3743 | INHERITED FROM: NAD(+) glycohydrolase || Hydrolyzing N-glycosyl compounds || Glycosylases |
| Pyruvate oxidase and decarboxylase, middle domain | 0.6149 | INHERITED FROM: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) || Acting on carbon-carbon bonds |
| I set domains | 0.7423 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Protein-tyrosine-phosphatase |
| Prokaryotic type I DNA topoisomerase | 0.7892 | INHERITED FROM: DNA helicase || Acting on ATP; involved in cellular and subcellular movement || Acting on acid anhydrides |
| Bromodomain | 0.8663 | INHERITED FROM: Adenosinetriphosphatase |
| FabD-like | 0.8864 | INHERITED FROM: Acting on ester bonds || Oleoyl-[acyl-carrier-protein] hydrolase || Thiolester hydrolases |
| mRNA cap (Guanine N-7) methyltransferase | 0.9019 | INHERITED FROM: Phosphoric monoester hydrolases || Polynucleotide 5'-phosphatase |
| Ras-binding domain, RBD | 0.9195 | INHERITED FROM: Phosphoric diester hydrolases || Phosphoinositide phospholipase C |
| WD40-repeat | 0.9376 | INHERITED FROM: Poly(A)-specific ribonuclease || Exoribonucleases producing 5'-phosphomonoesters |
| GGDEF domain | 0.9544 | INHERITED FROM: Phosphoric diester hydrolases || Cyclic-guanylate-specific phosphodiesterase |
| Ribonuclease Rh-like | 0.9668 | INHERITED FROM: Nucleoside-triphosphate phosphatase || Acting on ATP; involved in cellular and subcellular movement || Serine endopeptidases || Pestivirus NS3 polyprotein peptidase || RNA helicase || In phosphorus-containing anhydrides |
| 5' to 3' exonuclease catalytic domain | 0.9693 | INHERITED FROM: Exodeoxyribonucleases producing 5'-phosphomonoesters || Exodeoxyribonuclease (lambda-induced) |
| Terpenoid cyclase N-terminal domain | 1 | INHERITED FROM: Diphosphoric monoester hydrolases || Geranyl diphosphate diphosphatase |
| LDH N-terminal domain-like | 1 | INHERITED FROM: Alpha-galactosidase || Maltose-6'-phosphate glucosidase || Galacturonan 1,4-alpha-galacturonidase || 6-phospho-beta-glucosidase || Alpha-glucosidase |
| Amidase signature (AS) enzymes | 1 | INHERITED FROM: In linear amides || Amidase || Fatty acid amide hydrolase || Allophanate hydrolase |
| Carbonic anhydrase | 1 | INHERITED FROM: Protein-tyrosine-phosphatase |
| SPRY domain | 1 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || RNA helicase |
| Tetratricopeptide repeat (TPR) | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Protein-serine/threonine phosphatase |
| Terpenoid cyclase C-terminal domain | 1 | INHERITED FROM: Diphosphoric monoester hydrolases || Geranyl diphosphate diphosphatase |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| Thiolase-related | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Acetyl-CoA hydrolase || Palmitoyl-CoA hydrolase || Thiolester hydrolases |
| ROK | 1 | INHERITED FROM: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) |
| PHD domain | 1 | INHERITED FROM: DNA helicase || Acting on ATP; involved in cellular and subcellular movement |
| Class II glutamine amidotransferases | 1 | INHERITED FROM: Gamma-glutamyl hercynylcysteine S-oxide hydrolase |
| DNA polymerase I | 1 | INHERITED FROM: Endoribonucleases producing 5'-phosphomonoesters || Ribonuclease H |
| SH2 domain | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Phosphoric diester hydrolases || Phosphoinositide 5-phosphatase || Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase || Inositol-polyphosphate 5-phosphatase || Phosphoinositide phospholipase C || Protein-tyrosine-phosphatase |
| CCCH zinc finger | 1 | INHERITED FROM: RNA helicase |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 1 | INHERITED FROM: Endodeoxyribonucleases producing 5'-phosphomonoesters || Deoxyribonuclease V |
| AraD-like aldolase/epimerase | 1 | INHERITED FROM: Acireductone synthase |
| Trehalose-6-phosphate synthase, OtsA | 1 | INHERITED FROM: Trehalose-phosphatase |
| Growth factor receptor domain | 1 | INHERITED FROM: Furin || Serine endopeptidases |
| Cofactor-dependent phosphoglycerate mutase | 1 | INHERITED FROM: Fructose-2,6-bisphosphate 2-phosphatase |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Thiolester hydrolases |
| Pyruvate oxidase and decarboxylase PP module | 1 | INHERITED FROM: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) || Acting on carbon-carbon bonds |
| L-histidinol dehydrogenase HisD | 1 | INHERITED FROM: Phosphoribosyl-AMP cyclohydrolase || Phosphoribosyl-ATP diphosphatase |
| Cold shock DNA-binding domain-like | 1 | INHERITED FROM: Acting on ester bonds || Exoribonuclease II || Ribonuclease E || Exoribonucleases producing 5'-phosphomonoesters |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: Dihydroorotase || In cyclic amides |
| Phosphate binding protein-like | 1 | INHERITED FROM: Alkaline phosphatase |
| Tyrosine-dependent oxidoreductases | 1 | INHERITED FROM: Acting on carbon-sulfur bonds || Oleoyl-[acyl-carrier-protein] hydrolase || UDP-sulfoquinovose synthase |
| Calcium ATPase, transduction domain A | 1 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| WW domain | 1 | INHERITED FROM: Acting on ATP; involved in cellular and subcellular movement || RNA helicase |
| RecA protein-like (ATPase-domain) | 1 | INHERITED FROM: Nucleoside-triphosphate phosphatase |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: In other compounds || 1-aminocyclopropane-1-carboxylate deaminase |
| Formyltransferase | 1 | INHERITED FROM: Formyltetrahydrofolate deformylase |
| Meta-cation ATPase, catalytic domain P | 1 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Alcohol dehydrogenase-like, C-terminal domain | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase |
| Crotonase-like | 1 | INHERITED FROM: Acting on carbon-carbon bonds || 4-chlorobenzoyl-CoA dehalogenase || Acting on halide bonds || 3-hydroxyisobutyryl-CoA hydrolase || Thiolester hydrolases || 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase |
| Nucleotide and nucleoside kinases | 1 | INHERITED FROM: Polynucleotide 3'-phosphatase |
| BC N-terminal domain-like | 1 | INHERITED FROM: Dihydroorotase |
| Aspartate/ornithine carbamoyltransferase | 1 | INHERITED FROM: Dihydroorotase |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Alpha-N-acetylgalactosaminidase |
| Calcium ATPase, transmembrane domain M | 1 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| HpcH/HpaI aldolase | 1 | INHERITED FROM: (3S)-malyl-CoA thioesterase || Thiolester hydrolases |
| Cystathionine synthase-like | 1 | INHERITED FROM: Acting on carbon-carbon bonds || Kynureninase |
| Alcohol dehydrogenase-like, N-terminal domain | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase |
| Glucose 6-phosphate dehydrogenase-like | 1 | INHERITED FROM: 6-phosphogluconolactonase |
| Pyruvate oxidase and decarboxylase Pyr module | 1 | INHERITED FROM: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) || Acting on carbon-carbon bonds |
| SH3-domain | 1 | INHERITED FROM: Phosphoric diester hydrolases || Phosphoinositide phospholipase C |
| beta-carbonic anhydrase, cab | 1 | INHERITED FROM: Acting on carbon-sulfur bonds || Carbon disulfide hydrolase |
| BC ATP-binding domain-like | 1 | INHERITED FROM: Dihydroorotase |
| SAM (sterile alpha motif) domain | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase |
| Imidazole glycerol phosphate dehydratase | 1 | INHERITED FROM: Phosphoric monoester hydrolases || Acting on ester bonds || Histidinol-phosphatase |
| Glutathione peroxidase-like | 1 | INHERITED FROM: Phospholipase A(2) |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Sphingomyelin phosphodiesterase-like | 0 | Direct |
| RecU-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Fibronectin type I module | 0 | Direct |
| ITPase (Ham1) | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| Zf-UBP | 0 | Direct |
| Alkaline phosphatase | 0 | Direct |
| Exodeoxyribonuclease V beta chain (RecB), C-terminal domain | 0 | Direct |
| HTLV-II matrix protein | 0 | Direct |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | Direct |
| Methylesterase CheB, C-terminal domain | 0 | Direct |
| tRNA splicing product Appr>p cyclic nucleotide phosphodiesterase | 0 | Direct |
| S-adenosylhomocystein hydrolase | 0 | Direct |
| Acyl-CoA thioesterase | 0 | Direct |
| M48USP-like | 0 | Direct |
| Tandem AAA-ATPase domain | 0 | Direct |
| ADPRibase-Mn-like | 0 | Direct |
| Plant invertase/pectin methylesterase inhibitor | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| alpha-mannosidase, domain 2 | 0 | Direct |
| Phospholipase C | 0 | Direct |
| Mismatch glycosylase | 0 | Direct |
| Carboxylesterase | 0 | Direct |
| YihX-like | 0 | Direct |
| Esterase | 0 | Direct |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| Peptidylarginine deiminase Pad4, catalytic C-terminal domain | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Glycerophosphoryl diester phosphodiesterase | 0 | Direct |
| CBM22 | 0 | Direct |
| CDH-like | 0 | Direct |
| Lysophospholipase | 0 | Direct |
| Putative isomerase YbhE | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| Hypothetical esterase YJL068C | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Germination protease | 0 | Direct |
| Ppx/GppA phosphatase | 0 | Direct |
| CobE/GbiG C-terminal domain-like | 0 | Direct |
| alpha-Subunit of urease | 0 | Direct |
| Hyaluronidase N-terminal domain-like | 0 | Direct |
| DUSP, domain in ubiquitin-specific proteases | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| Phosphotriesterase-like | 0 | Direct |
| Dac-like | 0 | Direct |
| Insect phospholipase A2 | 0 | Direct |
| Thermolysin-like | 0 | Direct |
| RNase P subunit p30 | 0 | Direct |
| Glycosyl hydrolases family 32 N-terminal domain | 0 | Direct |
| Ribonuclease H | 0 | Direct |
| Galacturonase | 0 | Direct |
| Viral proteases | 0 | Direct |
| HAD-related | 0 | Direct |
| DTD-like | 0 | Direct |
| Arginine deiminase | 0 | Direct |
| GUCT domain | 0 | Direct |
| PepX catalytic domain-like | 0 | Direct |
| Dihydroorotase | 0 | Direct |
| RNase III catalytic domain-like | 0 | Direct |
| Alpha-toxin, C-terminal domain | 0 | Direct |
| BRK domain-like | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| Gastric lipase | 0 | Direct |
| Vertebrate phospholipase A2 | 0 | Direct |
| Glycosyl Hydrolase Family 88 | 0 | Direct |
| TNF-alpha converting enzyme, TACE, catalytic domain | 0 | Direct |
| LmbE-like | 0 | Direct |
| TMV-like viral coat proteins | 0 | Direct |
| Viral cysteine protease of trypsin fold | 0 | Direct |
| Zn metallo-beta-lactamase | 0 | Direct |
| HtrA-like serine proteases | 0 | Direct |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | Direct |
| CinA-like | 0 | Direct |
| Leukotriene A4 hydrolase catalytic domain | 0 | Direct |
| Elongation factors | 0 | Direct |
| AglA-like glucosidase | 0 | Direct |
| Fibronectin type II module | 0 | Direct |
| Proprotein convertase P-domain | 0 | Direct |
| Pancreatic carboxypeptidase, activation domain | 0 | Direct |
| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC | 0 | Direct |
| MtnX-like | 0 | Direct |
| Sulfolobus fructose-1,6-bisphosphatase-like | 0 | Direct |
| Family 9 carbohydrate-binding module, CBD9 | 0 | Direct |
| Cellulose-binding domain family II | 0 | Direct |
| Cytidine deaminase | 0 | Direct |
| ATP-dependent protease Lon (La), catalytic domain | 0 | Direct |
| RecQ helicase DNA-binding domain-like | 0 | Direct |
| Phosphonoacetate hydrolase | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| mRNA decapping enzyme DcpS C-terminal domain | 0 | Direct |
| Papain-like | 0 | Direct |
| Peptidyl-tRNA hydrolase domain | 0 | Direct |
| Class B acid phosphatase, AphA | 0 | Direct |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | Direct |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | Direct |
| Glyoxalase II (hydroxyacylglutathione hydrolase) | 0 | Direct |
| NSP3A-like | 0 | Direct |
| Glutaminase | 0 | Direct |
| Staphopain B, prodomain | 0 | Direct |
| Exodeoxyribonuclease V beta chain (RecC), C-terminal domain | 0 | Direct |
| Tetrahydrofolate dehydrogenase/cyclohydrolase | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Peptide deformylase | 0 | Direct |
| Tail specific protease, catalytic domain | 0 | Direct |
| Apyrase | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Mason-Pfizer monkey virus matrix protein | 0 | Direct |
| C-terminal, Zn-finger domain of MutM-like DNA repair proteins | 0 | Direct |
| Glutaminase/Asparaginase | 0 | Direct |
| MutY C-terminal domain-like | 0 | Direct |
| MgsA/YrvN C-terminal domain-like | 0 | Direct |
| Shiga toxin, A-chain | 0 | Direct |
| Prohormone convertase 1 pro-domain | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| Arylsulfatase | 0 | Direct |
| Clostridium neurotoxins, C-terminal domain | 0 | Direct |
| Penicillin acylase, catalytic domain | 0 | Direct |
| Phosphoserine phosphatase | 0 | Direct |
| PKD domain | 0 | Direct |
| Cutinase-like | 0 | Direct |
| Initiation factor IF2/eIF5b, domain 3 | 0 | Direct |
| Dextranase, N-terminal domain | 0 | Direct |
| SEA domain | 0 | Direct |
| alpha-L-arabinanase-like | 0 | Direct |
| Serralysin-like metalloprotease, catalytic (N-terminal) domain | 0 | Direct |
| Type 1 signal peptidase | 0 | Direct |
| Dimethylarginine dimethylaminohydrolase DDAH | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Biotin biosynthesis protein BioH | 0 | Direct |
| Fungal lipases | 0 | Direct |
| AF0625-like | 0 | Direct |
| Methionine aminopeptidase, insert domain | 0 | Direct |
| ADP ribosyl cyclase-like | 0 | Direct |
| DPP6 catalytic domain-like | 0 | Direct |
| Dual specificity phosphatase-like | 0 | Direct |
| Family 28 carbohydrate binding module, CBM28 | 0 | Direct |
| Predicted hydrolases Cof | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| R3H domain | 0 | Direct |
| Purple acid phosphatase-like | 0 | Direct |
| MoCo carrier protein-like | 0 | Direct |
| Glycosyl hydrolases family 32 C-terminal domain | 0 | Direct |
| Alpha-L-arabinofuranosidase B, N-terminal domain | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| GRAM domain | 0 | Direct |
| Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF1 | 0 | Direct |
| FMDV leader protease | 0 | Direct |
| Hjc-like | 0 | Direct |
| Serine carboxypeptidase-like | 0 | Direct |
| Pancreatic carboxypeptidases | 0 | Direct |
| Transthyretin (synonym: prealbumin) | 0 | Direct |
| LamB/YcsF-like | 0 | Direct |
| Family 17 carbohydrate binding module, CBM17 | 0 | Direct |
| Z-DNA binding domain | 0 | Direct |
| Allantoicase repeat | 0 | Direct |
| RNA helicase | 0 | Direct |
| Janus/Ocnus | 0 | Direct |
| Sec63 C-terminal domain-like | 0 | Direct |
| D-aminoacylase, catalytic domain | 0 | Direct |
| Family 1 of glycosyl hydrolase | 0 | Direct |
| (Glycosyl)asparaginase | 0 | Direct |
| Amylase, catalytic domain | 0 | Direct |
| Putative alpha-L-fucosidase, catalytic domain | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| 2'-5' RNA ligase LigT | 0 | Direct |
| Type X cellulose binding domain, CBDX | 0 | Direct |
| Carboxypeptidase T | 0 | Direct |
| CBM11 | 0 | Direct |
| Dcp2 box A domain | 0 | Direct |
| Formate/glycerate dehydrogenases, NAD-domain | 0 | Direct |
| NagD-like | 0 | Direct |
| Epoxide hydrolase | 0 | Direct |
| Deoxycytidylate deaminase-like | 0 | Direct |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | Direct |
| LexA-related | 0 | Direct |
| RuvC resolvase | 0 | Direct |
| Ku70 subunit middle domain | 0 | Direct |
| 1,4-beta-N-acetylmuraminidase | 0 | Direct |
| Sec63 N-terminal domain | 0 | Direct |
| Gamma-glutamyltranspeptidase-like | 0 | Direct |
| Nsp15 N-terminal domain-like | 0 | Direct |
| Retrovirus capsid protein C-terminal domain | 0 | Direct |
| Peptidyl-tRNA hydrolase II | 0 | Direct |
| beta-Galactosidase/glucuronidase, N-terminal domain | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| XseB-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| N-acetylglucosamine-6-phosphate deacetylase, NagA | 0 | Direct |
| Pepsin-like | 0 | Direct |
| EAL domain | 0 | Direct |
| Sialidases (neuraminidases) | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Plant cytotoxins | 0 | Direct |
| Archaeal IMP cyclohydrolase PurO | 0 | Direct |
| Isochorismatase-like hydrolases | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Coronavirus NSP7-like | 0 | Direct |
| LD-carboxypeptidase A N-terminal domain-like | 0 | Direct |
| DNA-binding domain from rap30 | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| Family 19 glycosidase | 0 | Direct |
| Ku70 subunit N-terminal domain | 0 | Direct |
| PUD-like | 0 | Direct |
| Pectin methylesterase | 0 | Direct |
| Serum paraoxonase/arylesterase 1, PON1 | 0 | Direct |
| Outer membrane phospholipase A (OMPLA) | 0 | Direct |
| AbfB domain | 0 | Direct |
| mRNA triphosphatase CET1 | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF1 | 0 | Direct |
| GTP cyclohydrolase I | 0 | Direct |
| G-type lysozyme | 0 | Direct |
| Urease, gamma-subunit | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| PDEase | 0 | Direct |
| Hydantoinase (dihydropyrimidinase) | 0 | Direct |
| D-aminoacylase | 0 | Direct |
| Penta-EF-hand proteins | 0 | Direct |
| Carboxypeptidase regulatory domain | 0 | Direct |
| NPCBM-like | 0 | Direct |
| NagZ-like | 0 | Direct |
| Peptidylarginine deiminase Pad4, N-terminal domain | 0 | Direct |
| SGL-like | 0 | Direct |
| Glycosyl hydrolases family 6, cellulases | 0 | Direct |
| C-terminal domain of Ku80 | 0 | Direct |
| Acyl-ACP thioesterase-like | 0 | Direct |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain | 0 | Direct |
| Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | Direct |
| Hepsin, N-terminal domain | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| DEATH effector domain, DED | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| CbiG N-terminal domain-like | 0 | Direct |
| LON domain-like | 0 | Direct |
| Proline iminopeptidase-like | 0 | Direct |
| Replication initiation protein E1 | 0 | Direct |
| RNB domain-like | 0 | Direct |
| Subtilases | 0 | Direct |
| Arginase-like amidino hydrolases | 0 | Direct |
| Actin/HSP70 | 0 | Direct |
| YlbA-like | 0 | Direct |
| Gingipain R (RgpB), N-terminal domain | 0 | Direct |
| DNA/RNA non-specific endonuclease | 0 | Direct |
| Leucine aminopeptidase (Aminopeptidase A), N-terminal domain | 0 | Direct |
| Chitosanase | 0 | Direct |
| Bee venom hyaluronidase | 0 | Direct |
| Thioesterases | 0 | Direct |
| Class II viral fusion proteins C-terminal domain | 0 | Direct |
| Cdc48 N-terminal domain-like | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| Integrin alpha N-terminal domain | 0 | Direct |
| Enolase-phosphatase E1 | 0 | Direct |
| HRDC domain from helicases | 0 | Direct |
| SARS Nsp1-like | 0 | Direct |
| RNase P subunit p29-like | 0 | Direct |
| Serine-carboxyl proteinase, SCP | 0 | Direct |
| Eukaryotic proteases | 0 | Direct |
| LexA repressor, N-terminal DNA-binding domain | 0 | Direct |
| Influenza hemagglutinin (stalk) | 0 | Direct |
| Cytosine deaminase catalytic domain | 0 | Direct |
| Hydantoinase (dihydropyrimidinase), catalytic domain | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| Peptidoglycan binding domain, PGBD | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| Caspase catalytic domain | 0 | Direct |
| N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain | 0 | Direct |
| Dextranase, catalytic domain | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| Carbon-carbon bond hydrolase | 0 | Direct |
| Virulence factor P.69 pertactin | 0 | Direct |
| Immunodeficiency virus matrix proteins | 0 | Direct |
| N-terminal domain of MutM-like DNA repair proteins | 0 | Direct |
| Matrix metalloproteases, catalytic domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| alpha-mannosidase, C-terminal domain | 0 | Direct |
| SAH/MTA deaminase-like | 0 | Direct |
| beta-N-acetylhexosaminidase catalytic domain | 0 | Direct |
| Caliciviridae-like VP | 0 | Direct |
| NodB-like polysaccharide deacetylase | 0 | Direct |
| Toll/Interleukin receptor TIR domain | 0 | Direct |
| GlpX-like bacterial fructose-1,6-bisphosphatase | 0 | Direct |
| RibA-like | 0 | Direct |
| Trehalose-phosphatase | 0 | Direct |
| Leishmanolysin | 0 | Direct |
| Prolyl oligopeptidase, N-terminal domain | 0 | Direct |
| Outer membrane protease OMPT | 0 | Direct |
| Pancreatic lipase, N-terminal domain | 0 | Direct |
| Trypanosoma sialidase, C-terminal domain | 0 | Direct |
| PBP5 C-terminal domain-like | 0 | Direct |
| Nsp15 C-terminal domain-like | 0 | Direct |
| Coronavirus NSP10-like | 0 | Direct |
| Aminopeptidase/glucanase lid domain | 0 | Direct |
| G proteins | 0 | Direct |
| Adenain-like | 0 | Direct |
| NADH pyrophosphatase | 0 | Direct |
| alpha-subunit of urease, catalytic domain | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| LD-carboxypeptidase A C-terminal domain-like | 0 | Direct |
| Bacterial dinuclear zinc exopeptidases | 0 | Direct |
| beta-glycanases | 0 | Direct |
| Endonuclease I | 0 | Direct |
| beta-Lactamase/D-ala carboxypeptidase | 0 | Direct |
| Glycosyl hydrolase family 7 catalytic core | 0 | Direct |
| HisI-like | 0 | Direct |
| Clostridium neurotoxins, catalytic domain | 0 | Direct |
| Putative serine hydrolase Ydr428c | 0 | Direct |
| Gingipain R (RgpB), C-terminal domain | 0 | Direct |
| GLA-domain | 0 | Direct |
| CAF1-like ribonuclease | 0 | Direct |
| DNA helicase RuvA subunit, middle domain | 0 | Direct |
| alpha-mannosidase | 0 | Direct |
| Achaeal helicase C-terminal domain | 0 | Direct |
| beta-Galactosidase, domain 5 | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Leucine aminopeptidase, C-terminal domain | 0 | Direct |
| Putative acetylxylan esterase-like | 0 | Direct |
| Putative glucosidase YicI, domain 3 | 0 | Direct |
| NagB-like | 0 | Direct |
| NlpC/P60 | 0 | Direct |
| RNase Z-like | 0 | Direct |
| Zinc protease | 0 | Direct |
| MutT-like | 0 | Direct |
| GAG polyprotein M-domain | 0 | Direct |
| NTF2-like | 0 | Direct |
| MMP N-terminal domain | 0 | Direct |
| Nuclease | 0 | Direct |
| 3-methyladenine DNA glycosylase (AAG, ANPG, MPG) | 0 | Direct |
| Invasin/intimin cell-adhesion fragments | 0 | Direct |
| Retroviral integrase, catalytic domain | 0 | Direct |
| Helicase-like "domain" of reverse gyrase | 0 | Direct |
| YicI catalytic domain-like | 0 | Direct |
| Extended PAW domain | 0 | Direct |
| MMLV matrix protein-like | 0 | Direct |
| Acetylcholinesterase-like | 0 | Direct |
| Uracil-DNA glycosylase | 0 | Direct |
| Hyaluronidase post-catalytic domain-like | 0 | Direct |
| AstE/AspA-like | 0 | Direct |
| RNase P protein | 0 | Direct |
| Acylamino-acid-releasing enzyme, C-terminal donain | 0 | Direct |
| Holliday junction resolvase RusA | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| Bacterial lipase | 0 | Direct |
| beta-N-acetylhexosaminidase domain | 0 | Direct |
| Nodaviridae-like VP | 0 | Direct |
| Proteasome subunits | 0 | Direct |
| beta-Galactosidase/glucuronidase domain | 0 | Direct |
| alpha-D-glucuronidase/Hyaluronidase catalytic domain | 0 | Direct |
| Coronavirus NSP8-like | 0 | Direct |
| mRNA decapping enzyme-like | 0 | Direct |
| P1 nuclease | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| Clp protease, ClpP subunit | 0 | Direct |
| EGF-type module | 0 | Direct |
| Fungal zinc peptidase | 0 | Direct |
| Putative cyclase | 0 | Direct |
| Integrin A (or I) domain | 0 | Direct |
| Histidinol phosphatase-like | 0 | Direct |
| Trehalase-like | 0 | Direct |
| Carbohydrate binding domain | 0 | Direct |
| Adenosine/AMP deaminase | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
| Ppx associated domain | 0 | Direct |
| Ku80 subunit middle domain | 0 | Direct |
| Creatininase | 0 | Direct |
| GW domain | 0 | Direct |
| D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
| Patatin | 0 | Direct |
| CheY-related | 0 | Direct |
| GpdQ-like | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| Endonuclease IV | 0 | Direct |
| beta-Phosphoglucomutase-like | 0 | Direct |
| Herpes virus serine proteinase, assemblin | 0 | Direct |
| SurE-like | 0 | Direct |
| Imidazolonepropionase-like | 0 | Direct |
| Sortase | 0 | Direct |
| Carbamilase | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| 4HBT-like | 0 | Direct |
| Clostridium neurotoxins, the second last domain | 0 | Direct |
| Neutral endopeptidase (neprilysin) | 0 | Direct |
| Staphylococcal nuclease | 0 | Direct |
| Succinylarginine dihydrolase-like | 0 | Direct |
| alpha-Amylases, C-terminal beta-sheet domain | 0 | Direct |
| Phosphonoacetaldehyde hydrolase-like | 0 | Direct |
| Beta-galactosidase LacA, domain 2 | 0 | Direct |
| Peptidyl-tRNA hydrolase-like | 0 | Direct |
| Mammalian PLC | 0 | Direct |
| Porphyromonas-type peptidylarginine deiminase | 0 | Direct |
| MazG-like | 0 | Direct |
| AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC | 0 | Direct |
| PP2C-like | 0 | Direct |
| Xylanase/endoglucanase 11/12 | 0 | Direct |
| Myotubularin-like phosphatases | 0 | Direct |
| RecG "wedge" domain | 0 | Direct |
| Cellulose-binding domain | 0 | Direct |
| Macro domain | 0 | Direct |
| Beta-galactosidase LacA, domain 3 | 0 | Direct |
| Renal dipeptidase | 0 | Direct |
| Cellulases catalytic domain | 0 | Direct |
| Phage lysozyme | 0 | Direct |
| DNA helicase RuvA subunit, N-terminal domain | 0 | Direct |
| YicI N-terminal domain-like | 0 | Direct |
| Sec-C motif | 0 | Direct |
| C-type lysozyme | 0 | Direct |
| Helicase DNA-binding domain | 0 | Direct |
| SAH/MTA deaminase-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| PepX C-terminal domain-like | 0 | Direct |
| Astacin | 0 | Direct |
| Inosicase | 0 | Direct |
| Reverse transcriptase | 0 | Direct |
| PA1517-like | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| 2',3'-cyclic nucleotide 3'-phosphodiesterase, catalytic domain | 0 | Direct |
| RNase D C-terminal domains | 0 | Direct |
| Cellulose-binding domain family III | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Type II chitinase | 0 | Direct |
| Ubiquitin thiolesterase protein OTUB2 (Otubain-2) | 0 | Direct |
| Urease, beta-subunit | 0 | Direct |
| PAZ domain | 0 | Direct |
| FolH catalytic domain-like | 0 | Direct |
| Rap30/74 interaction domains | 0 | Direct |
| Rpp14/Pop5-like | 0 | Direct |
| VanX-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| Trefoil | 0 | Direct |
| Toprim domain | 0 | Direct |
| alpha-D-glucuronidase, N-terminal domain | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| Composite domain of glycosyl hydrolase families 5, 30, 39 and 51 | 0 | Direct |
| Mug-like | 0 | Direct |
| Colipase-binding domain | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| Maf-like | 0 | Direct |
| Retroviral protease (retropepsin) | 0 | Direct |
| Acetamidase/Formamidase-like | 0 | Direct |
| Eng V-like | 0 | Direct |
| Leukotriene A4 hydrolase C-terminal domain | 0 | Direct |
| N-terminal domain of DnaB helicase | 0 | Direct |
| Type 2 phosphatidic acid phosphatase, PAP2 | 0 | Direct |
| mRNA cap methylase | 0 | Direct |
| Bacterial ribonucleases | 0 | Direct |
| Type I dockerin domain | 0 | Direct |
| Glycosyl hydrolases family 35 catalytic domain | 0 | Direct |
| Inorganic pyrophosphatase | 0 | Direct |
| Collagen-binding domain | 0 | Direct |
| RNA-dependent RNA-polymerase | 0 | Direct |
| CBM4/9 | 0 | Direct |
| Acylphosphatase-like | 0 | Direct |
| MPP-like | 0 | Direct |
| Pyrimidine 5'-nucleotidase (UMPH-1) | 0 | Direct |
| TIP49 domain | 0 | Direct |
| CheD-like | 0 | Direct |
| Subtilase propeptides/inhibitors | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| Neurolysin-like | 0 | Direct |
| ComB-like | 0 | Direct |
| Imidazolonepropionase-like | 0 | Direct |
| Parvoviridae-like VP | 0 | Direct |
| Bacterial chitobiase, n-terminal domain | 0 | Direct |
| N-terminal domain of RNase HI | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| Bacterial GAP domain | 0 | Direct |
| Prokaryotic proteases | 0 | Direct |
| Glucoamylase | 0 | Direct |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | Direct |
| TAP-like | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| dUTPase-like | 0 | Direct |
| Extended AAA-ATPase domain | 0 | Direct |
| A4 beta-galactosidase middle domain | 0 | Direct |
| Dienelactone hydrolase | 0 | Direct |
| Nitrilase | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| YdjC-like | 0 | Direct |
| Prolyl oligopeptidase, C-terminal domain | 0 | Direct |
| cAMP-binding domain | 0 | Direct |
| Ku80 subunit N-terminal domain | 0 | Direct |
| HisE-like (PRA-PH) | 0 | Direct |
| Inositol monophosphatase/fructose-1,6-bisphosphatase-like | 0 | Direct |
| Penicillin binding protein dimerisation domain | 0 | Direct |
| Middle domain of MutM-like DNA repair proteins | 0 | Direct |
| EF-G/eEF-2 domains III and V | 0 | Direct |
| Replicase NSP9 | 0 | Direct |
| Manganese-dependent inorganic pyrophosphatase (family II) | 0 | Direct |
| Magnesium-dependent phosphatase-1, Mdp1 | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Beta-D-xylosidase C-terminal domain-like | 0 | Direct |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | Direct |
| Cellulose docking domain, dockering | 0 | Direct |
| Hevein-like agglutinin (lectin) domain | 0 | Direct |
| Thermostable phytase (3-phytase) | 0 | Direct |
| 5' nucleotidase-like | 0 | Direct |
| Nucleoside hydrolase | 0 | Direct |
| Virulence effector SptP domain | 0 | Direct |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
| Aspartyl dipeptidase PepE | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| NLI interacting factor-like phosphatase | 0 | Direct |
| Beta-galactosidase LacA, domains 4 and 5 | 0 | Direct |
| Kringle modules | 0 | Direct |
| HD domain | 3.693e-16 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain | 3.693e-16 | Direct |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain | 0.000000000000002732 | Direct |
| MAM domain | 0.000000000000004356 | Direct |
| PA domain | 0.000000000000005436 | Direct |
| LysM domain | 0.00000000000003329 | Direct |
| DJ-1/PfpI | 0.00000000000008783 | Direct |
| EF-hand modules in multidomain proteins | 0.0000000000001042 | Direct |
| Haloalkane dehalogenase | 0.0000000000006696 | Direct |
| Purine and uridine phosphorylases | 0.000000000002011 | Direct |
| Nitrous oxide reductase, N-terminal domain | 0.000000000002366 | Direct |
| GAF domain | 0.00000000001962 | Direct |
| Caspase recruitment domain, CARD | 0.00000000002198 | Direct |
| HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0.0000000002793 | Direct |
| Fungal ribonucleases | 0.0000000002793 | Direct |
| YjgF/L-PSP | 0.0000000007256 | Direct |
| Low-molecular-weight phosphotyrosine protein phosphatases | 0.0000000007361 | Direct |
| Tudor domain | 0.000000004515 | Direct |
| 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB | 0.000000007392 | Direct |
| Chromo domain | 0.000000008821 | Direct |
| LDL receptor-like module | 0.00000006839 | Direct |
| HCP-like | 0.0000001569 | Direct |
| TENA/THI-4 | 0.0000002849 | Direct |
| CYTH domain | 0.0000003816 | Direct |
| Starch-binding domain | 0.000000396 | Direct |
| Fibronectin type III | 0.0000003997 | Direct |
| Acetylhydrolase | 0.0000007617 | Direct |
| Peptidoglycan hydrolase LytM | 0.0000007617 | Direct |
| Ubiquitin-related | 0.000003163 | Direct |
| Serralysin-like metalloprotease, C-terminal domain | 0.000004648 | Direct |
| Glycosyl hydrolases family 16 | 0.00000596 | Direct |
| PUG domain | 0.000006062 | Direct |
| phosphatase domain of polynucleotide kinase | 0.00001784 | Direct |
| UBA domain | 0.00001997 | Direct |
| MATH domain | 0.00003045 | Direct |
| Pleckstrin-homology domain (PH domain) | 0.00003228 | Direct |
| PH0987 C-terminal domain-like | 0.00008657 | Direct |
| E-set domains of sugar-utilizing enzymes | 0.0001124 | Direct |
| Family 6 carbohydrate binding module, CBM6 | 0.0001147 | Direct |
| MYND zinc finger | 0.0001147 | Direct |
| Transglutaminase core | 0.0002342 | Direct |
| RibD C-terminal domain-like | 0.0003243 | Direct |
| PH0987 N-terminal domain-like | 0.0004187 | Direct |
| PaaI/YdiI-like | 0.0004187 | Direct |
| DEK C-terminal domain | 0.0004886 | Direct |
| 4-alpha-glucanotransferase, N-terminal domain | 0.0004886 | Direct |
| Acyl-carrier protein (ACP) | 0.0004886 | Direct |
| Third domain of FERM | 0.0005077 | Direct |
| Cell wall binding repeat | 0.001633 | Inherited |
| Anthrax toxin lethal factor, N- and C-terminal domains | 0.002032 | Inherited |
| GS domain | 0.002032 | Inherited |
| Galactose-binding domain | 0.002046 | Inherited |
| 4-alpha-glucanotransferase, domain 2 | 0.002046 | Inherited |
| 4-alpha-glucanotransferase, C-terminal domain | 0.002046 | Inherited |
| Ras GEF | 0.002046 | Inherited |
| DNase I-like | 0.002119 | Inherited |
| SAP domain | 0.002868 | Inherited |
| DNA repair glycosylase, 2 C-terminal domains | 0.003104 | Inherited |
| First domain of FERM | 0.003289 | Inherited |
| BCR-homology GTPase activation domain (BH-domain) | 0.003906 | Inherited |
| DnaQ-like 3'-5' exonuclease | 0.004738 | Inherited |
| Ricin B-like | 0.004833 | Inherited |
| FAH | 0.004845 | Inherited |
| Probable phosphatase YrbI | 0.005439 | Inherited |
| Hydroxynitrile lyase-like | 0.008335 | Inherited |
| F-box domain | 0.008335 | Inherited |
| MIT domain | 0.01143 | Inherited |
| Intein (protein splicing domain) | 0.0189 | Inherited |
| Chaperone J-domain | 0.02077 | Inherited |
| Glycosyltransferase family 36 C-terminal domain | 0.02187 | Inherited |
| Thioesterase domain of polypeptide, polyketide and fatty acid synthases | 0.02246 | Inherited |
| Second domain of FERM | 0.02325 | Inherited |
| Leucine rich effector protein YopM | 0.02398 | Inherited |
| PX domain | 0.034 | Inherited |
| PHP domain | 0.04841 | Inherited |
| Haloperoxidase | 0.06732 | Inherited |
| UDP-N-acetylglucosamine 2-epimerase | 0.06838 | Inherited |
| Canonical RBD | 0.08217 | Inherited |
| MaoC-like | 0.08659 | Inherited |
| PDZ domain | 0.08659 | Inherited |
| Ran binding protein zinc finger-like | 0.08942 | Inherited |
| FHA domain | 0.0958 | Inherited |
| DNA repair glycosylase, N-terminal domain | 0.1015 | Inherited |
| mRNA capping enzyme | 0.1532 | Inherited |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.1565 | Inherited |
| RelA/SpoT domain | 0.1849 | Inherited |
| Scavenger receptor cysteine-rich (SRCR) domain | 0.1918 | Inherited |
| PP1699/LP2961-like | 0.1925 | Inherited |
| CoA transferase alpha subunit-like | 0.2421 | Inherited |
| HMA, heavy metal-associated domain | 0.2437 | Inherited |
| AlkB-like | 0.2792 | Inherited |
| PBP transglycosylase domain-like | 0.2821 | Inherited |
| Ankyrin repeat | 0.3277 | Inherited |
| Ecto-ART | 0.3743 | Inherited |
| Pyruvate oxidase and decarboxylase, middle domain | 0.6149 | Inherited |
| I set domains | 0.7423 | Inherited |
| Prokaryotic type I DNA topoisomerase | 0.7892 | Inherited |
| Bromodomain | 0.8663 | Inherited |
| FabD-like | 0.8864 | Inherited |
| mRNA cap (Guanine N-7) methyltransferase | 0.9019 | Inherited |
| Ras-binding domain, RBD | 0.9195 | Inherited |
| WD40-repeat | 0.9376 | Inherited |
| GGDEF domain | 0.9544 | Inherited |
| Ribonuclease Rh-like | 0.9668 | Inherited |
| 5' to 3' exonuclease catalytic domain | 0.9693 | Inherited |
| Terpenoid cyclase N-terminal domain | 1 | Inherited |
| LDH N-terminal domain-like | 1 | Inherited |
| Amidase signature (AS) enzymes | 1 | Inherited |
| Carbonic anhydrase | 1 | Inherited |
| SPRY domain | 1 | Inherited |
| Tetratricopeptide repeat (TPR) | 1 | Inherited |
| Terpenoid cyclase C-terminal domain | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| Thiolase-related | 1 | Inherited |
| ROK | 1 | Inherited |
| PHD domain | 1 | Inherited |
| Class II glutamine amidotransferases | 1 | Inherited |
| DNA polymerase I | 1 | Inherited |
| SH2 domain | 1 | Inherited |
| CCCH zinc finger | 1 | Inherited |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 1 | Inherited |
| AraD-like aldolase/epimerase | 1 | Inherited |
| Trehalose-6-phosphate synthase, OtsA | 1 | Inherited |
| Growth factor receptor domain | 1 | Inherited |
| Cofactor-dependent phosphoglycerate mutase | 1 | Inherited |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | Inherited |
| Pyruvate oxidase and decarboxylase PP module | 1 | Inherited |
| L-histidinol dehydrogenase HisD | 1 | Inherited |
| Cold shock DNA-binding domain-like | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
| Phosphate binding protein-like | 1 | Inherited |
| Tyrosine-dependent oxidoreductases | 1 | Inherited |
| Calcium ATPase, transduction domain A | 1 | Inherited |
| WW domain | 1 | Inherited |
| RecA protein-like (ATPase-domain) | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| Formyltransferase | 1 | Inherited |
| Meta-cation ATPase, catalytic domain P | 1 | Inherited |
| Alcohol dehydrogenase-like, C-terminal domain | 1 | Inherited |
| Crotonase-like | 1 | Inherited |
| Nucleotide and nucleoside kinases | 1 | Inherited |
| BC N-terminal domain-like | 1 | Inherited |
| Aspartate/ornithine carbamoyltransferase | 1 | Inherited |
| Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Calcium ATPase, transmembrane domain M | 1 | Inherited |
| HpcH/HpaI aldolase | 1 | Inherited |
| Cystathionine synthase-like | 1 | Inherited |
| Alcohol dehydrogenase-like, N-terminal domain | 1 | Inherited |
| Glucose 6-phosphate dehydrogenase-like | 1 | Inherited |
| Pyruvate oxidase and decarboxylase Pyr module | 1 | Inherited |
| SH3-domain | 1 | Inherited |
| beta-carbonic anhydrase, cab | 1 | Inherited |
| BC ATP-binding domain-like | 1 | Inherited |
| SAM (sterile alpha motif) domain | 1 | Inherited |
| Imidazole glycerol phosphate dehydratase | 1 | Inherited |
| Glutathione peroxidase-like | 1 | Inherited |
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this EC term (SPEC level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Aminopeptidase/glucanase lid domain | 0 | DIRECT |
| PKD domain | 0 | DIRECT |
| Galactose-binding domain-like | 0 | DIRECT |
| Lysozyme-like | 0 | DIRECT |
| Nucleoside hydrolase | 0 | DIRECT |
| Glutaminase/Asparaginase | 0 | DIRECT |
| N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
| AN1-like Zinc finger | 0 | DIRECT |
| "Winged helix" DNA-binding domain | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Methylglyoxal synthase-like | 0 | DIRECT |
| Retrovirus capsid dimerization domain-like | 0 | DIRECT |
| Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
| Voltage-gated potassium channels | 0 | DIRECT |
| Ribonuclease H-like | 0 | DIRECT |
| PAZ domain | 0 | DIRECT |
| DUSP-like | 0 | DIRECT |
| LD-carboxypeptidase A C-terminal domain-like | 0 | DIRECT |
| Carboxypeptidase regulatory domain-like | 0 | DIRECT |
| ClpP/crotonase | 0 | DIRECT |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Peptidyl-tRNA hydrolase-like | 0 | DIRECT |
| Flavivirus capsid protein C | 0 | DIRECT |
| ComB-like | 0 | DIRECT |
| Nitrous oxide reductase, N-terminal domain | 0 | DIRECT |
| CinA-like | 0 | DIRECT |
| Sec-C motif | 0 | DIRECT |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
| HisI-like | 0 | DIRECT |
| ADP-ribosylglycohydrolase | 0 | DIRECT |
| Toprim domain | 0 | DIRECT |
| Peptide deformylase | 0 | DIRECT |
| (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
| Penicillin-binding protein associated domain | 0 | DIRECT |
| Carbon-nitrogen hydrolase | 0 | DIRECT |
| Glycoside hydrolase/deacetylase | 0 | DIRECT |
| Invasin/intimin cell-adhesion fragments | 0 | DIRECT |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | DIRECT |
| Archaeal IMP cyclohydrolase PurO | 0 | DIRECT |
| Kazal-type serine protease inhibitors | 0 | DIRECT |
| EF-G C-terminal domain-like | 0 | DIRECT |
| Glycosyl hydrolase domain | 0 | DIRECT |
| Uracil-DNA glycosylase-like | 0 | DIRECT |
| Putative cyclase | 0 | DIRECT |
| Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
| Phage fibre proteins | 0 | DIRECT |
| EGF/Laminin | 0 | DIRECT |
| Penicillin binding protein dimerisation domain | 0 | DIRECT |
| Trefoil | 0 | DIRECT |
| Sec63 N-terminal domain-like | 0 | DIRECT |
| Carbohydrate phosphatase | 0 | DIRECT |
| Cellulose-binding domain | 0 | DIRECT |
| Urease, gamma-subunit | 0 | DIRECT |
| Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
| Apyrase | 0 | DIRECT |
| Cellulose docking domain, dockering | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Spermadhesin, CUB domain | 0 | DIRECT |
| Initiation factor IF2/eIF5b, domain 3 | 0 | DIRECT |
| Transferrin receptor-like dimerisation domain | 0 | DIRECT |
| DPP6 N-terminal domain-like | 0 | DIRECT |
| Hyaluronidase post-catalytic domain-like | 0 | DIRECT |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | DIRECT |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | DIRECT |
| Herpes virus serine proteinase, assemblin | 0 | DIRECT |
| Viral leader polypeptide zinc finger | 0 | DIRECT |
| CNF1/YfiH-like putative cysteine hydrolases | 0 | DIRECT |
| SEA domain | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | DIRECT |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
| SGNH hydrolase | 0 | DIRECT |
| Peptidyl-tRNA hydrolase II | 0 | DIRECT |
| Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
| Sortase | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| L9 N-domain-like | 0 | DIRECT |
| Cdc48 domain 2-like | 0 | DIRECT |
| Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
| Replicase NSP9 | 0 | DIRECT |
| all-alpha NTP pyrophosphatases | 0 | DIRECT |
| Six-hairpin glycosidases | 0 | DIRECT |
| Creatinase/prolidase N-terminal domain | 0 | DIRECT |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | DIRECT |
| Zn-dependent exopeptidases | 0 | DIRECT |
| Cap-Gly domain | 0 | DIRECT |
| Acid proteases | 0 | DIRECT |
| SARS Nsp1-like | 0 | DIRECT |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
| Kringle-like | 0 | DIRECT |
| Rof/RNase P subunit-like | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| Concanavalin A-like lectins/glucanases | 0 | DIRECT |
| Acetamidase/Formamidase-like | 0 | DIRECT |
| DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
| Coronavirus NSP8-like | 0 | DIRECT |
| Coronavirus NSP10-like | 0 | DIRECT |
| CheY-like | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
| DNase I-like | 0 | DIRECT |
| Rap30/74 interaction domains | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Creatininase | 0 | DIRECT |
| LigT-like | 0 | DIRECT |
| Dcp2 domain-like | 0 | DIRECT |
| FabD/lysophospholipase-like | 0 | DIRECT |
| Carbohydrate binding domain | 0 | DIRECT |
| Thermostable phytase (3-phytase) | 0 | DIRECT |
| Metallo-dependent hydrolases | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| DNA primase core | 0 | DIRECT |
| TMV-like viral coat proteins | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Outer membrane phospholipase A (OMPLA) | 0 | DIRECT |
| Sulfolobus fructose-1,6-bisphosphatase-like | 0 | DIRECT |
| C-terminal domain of PLC-beta | 0 | DIRECT |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | DIRECT |
| EndoU-like | 0 | DIRECT |
| alpha/beta-Hydrolases | 0 | DIRECT |
| Cytidine deaminase-like | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| His-Me finger endonucleases | 0 | DIRECT |
| Phospholipase A2, PLA2 | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Coronavirus NSP7-like | 0 | DIRECT |
| LmbE-like | 0 | DIRECT |
| STI-like | 0 | DIRECT |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | DIRECT |
| Nudix | 0 | DIRECT |
| Inorganic pyrophosphatase | 0 | DIRECT |
| P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
| Metallo-dependent phosphatases | 0 | DIRECT |
| Metallo-hydrolase/oxidoreductase | 0 | DIRECT |
| Methylesterase CheB, C-terminal domain | 0 | DIRECT |
| Plant lectins/antimicrobial peptides | 0 | DIRECT |
| Viral protein domain | 0 | DIRECT |
| Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
| GLA-domain | 0 | DIRECT |
| Isochorismatase-like hydrolases | 0 | DIRECT |
| beta-lactamase/transpeptidase-like | 0 | DIRECT |
| Transthyretin (synonym: prealbumin) | 0 | DIRECT |
| CRAL/TRIO N-terminal domain | 0 | DIRECT |
| HIT-like | 0 | DIRECT |
| PH domain-like | 0 | DIRECT |
| AlbA-like | 0 | DIRECT |
| N-terminal domain of DnaB helicase | 0 | DIRECT |
| Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
| PP2C-like | 0 | DIRECT |
| Putative isomerase YbhE | 0 | DIRECT |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| CbiG N-terminal domain-like | 0 | DIRECT |
| Retroviral matrix proteins | 0 | DIRECT |
| Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
| Pentein | 0 | DIRECT |
| Galactose mutarotase-like | 0 | DIRECT |
| Hemopexin-like domain | 0 | DIRECT |
| Cystatin/monellin | 0 | DIRECT |
| BRK domain-like | 0 | DIRECT |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | DIRECT |
| Peptidyl-tRNA hydrolase domain-like | 0 | DIRECT |
| Influenza hemagglutinin (stalk) | 0 | DIRECT |
| Arginase/deacetylase | 0 | DIRECT |
| cAMP-binding domain-like | 0 | DIRECT |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
| DTD-like | 0 | DIRECT |
| CobE/GbiG C-terminal domain-like | 0 | DIRECT |
| DNA-binding domain of retroviral integrase | 0 | DIRECT |
| DHH phosphoesterases | 0 | DIRECT |
| SurE-like | 0 | DIRECT |
| C-terminal domain of Ku80 | 0 | DIRECT |
| Cysteine proteinases | 0 | DIRECT |
| Acylphosphatase/BLUF domain-like | 0 | DIRECT |
| CYTH-like phosphatases | 0 | DIRECT |
| HybD-like | 0 | DIRECT |
| Holliday junction resolvase RusA | 0 | DIRECT |
| Type I dockerin domain | 0 | DIRECT |
| TSP-1 type 1 repeat | 0 | DIRECT |
| D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
| Hedgehog/DD-peptidase | 0 | DIRECT |
| Glycosyl hydrolases family 6, cellulases | 0 | DIRECT |
| beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
| Invertebrate chitin-binding proteins | 0 | DIRECT |
| MCP/YpsA-like | 0 | DIRECT |
| Beta-galactosidase LacA, domain 3 | 0 | DIRECT |
| Toll/Interleukin receptor TIR domain | 0 | DIRECT |
| S13-like H2TH domain | 0 | DIRECT |
| AF0625-like | 0 | DIRECT |
| Macro domain-like | 0 | DIRECT |
| Protease propeptides/inhibitors | 0 | DIRECT |
| Dextranase, N-terminal domain | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| (Trans)glycosidases | 0 | DIRECT |
| Trypsin-like serine proteases | 0 | DIRECT |
| Type X cellulose binding domain, CBDX | 0 | DIRECT |
| LexA/Signal peptidase | 0 | DIRECT |
| RibA-like | 0 | DIRECT |
| Urease, beta-subunit | 0 | DIRECT |
| HAD-like | 0 | DIRECT |
| beta-N-acetylhexosaminidase-like domain | 0 | DIRECT |
| Saposin | 0 | DIRECT |
| Xylose isomerase-like | 0 | DIRECT |
| Viral glycoprotein, central and dimerisation domains | 0 | DIRECT |
| Bacterial GAP domain | 0 | DIRECT |
| Anthrax protective antigen | 0 | DIRECT |
| Peptidase/esterase 'gauge' domain | 0 | DIRECT |
| Ribosome inactivating proteins (RIP) | 0 | DIRECT |
| SpoIIaa-like | 0 | DIRECT |
| dUTPase-like | 0 | DIRECT |
| Sialidases | 0 | DIRECT |
| ssDNA viruses | 0 | DIRECT |
| Arabinanase/levansucrase/invertase | 0 | DIRECT |
| Chitinase insertion domain | 0 | DIRECT |
| OMPT-like | 0 | DIRECT |
| Complement control module/SCR domain | 0 | DIRECT |
| XseB-like | 0 | DIRECT |
| PLC-like phosphodiesterases | 0 | DIRECT |
| NSP3A-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Phospholipase C/P1 nuclease | 0 | DIRECT |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| Origin of replication-binding domain, RBD-like | 0 | DIRECT |
| Creatinase/aminopeptidase | 0 | DIRECT |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | DIRECT |
| Positive stranded ssRNA viruses | 0 | DIRECT |
| AbfB domain | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| ITPase-like | 0 | DIRECT |
| PDZ domain-like | 0 | DIRECT |
| Autotransporter | 0 | DIRECT |
| Leukotriene A4 hydrolase N-terminal domain | 0 | DIRECT |
| Rnp2-like | 0 | DIRECT |
| Carbohydrate-binding domain | 0 | DIRECT |
| N-terminal domain of MutM-like DNA repair proteins | 0 | DIRECT |
| Somatomedin B domain | 0 | DIRECT |
| Collagen-binding domain | 0 | DIRECT |
| Prokaryotic SH3-related domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Plant invertase/pectin methylesterase inhibitor | 0 | DIRECT |
| RuvA domain 2-like | 0 | DIRECT |
| Purple acid phosphatase, N-terminal domain | 0 | DIRECT |
| PGBD-like | 0 | DIRECT |
| E set domains | 1.78e-16 | DIRECT |
| HD-domain/PDEase-like | 1.78e-16 | DIRECT |
| vWA-like | 0.000000000000002809 | DIRECT |
| LysM domain | 0.00000000000002358 | DIRECT |
| Calcium-dependent phosphotriesterase | 0.00000000000003215 | DIRECT |
| EF-hand | 0.00000000000004279 | DIRECT |
| Translation proteins | 0.00000000000004382 | DIRECT |
| Microbial ribonucleases | 0.00000000000007573 | DIRECT |
| Purine and uridine phosphorylases | 0.0000000000002683 | DIRECT |
| EAL domain-like | 0.0000000000003752 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0.000000000002328 | DIRECT |
| Tudor/PWWP/MBT | 0.00000000001395 | DIRECT |
| Phosphotyrosine protein phosphatases I | 0.00000000002229 | DIRECT |
| Staphylococcal nuclease | 0.0000000005812 | DIRECT |
| Ubiquitin-like | 0.0000000006239 | DIRECT |
| UBA-like | 0.000000001634 | DIRECT |
| DEATH domain | 0.000000009677 | DIRECT |
| PA domain | 0.00000001122 | DIRECT |
| Hairpin loop containing domain-like | 0.00000001244 | DIRECT |
| YjgF-like | 0.00000001816 | DIRECT |
| GAF domain-like | 0.00000002764 | DIRECT |
| LDL receptor-like module | 0.00000005715 | DIRECT |
| Phospholipase D/nuclease | 0.00000006593 | DIRECT |
| Fibronectin type III | 0.0000002224 | DIRECT |
| NagB/RpiA/CoA transferase-like | 0.0000002904 | DIRECT |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.0000003132 | DIRECT |
| Starch-binding domain-like | 0.0000008391 | DIRECT |
| N-(deoxy)ribosyltransferase-like | 0.000001362 | DIRECT |
| Phosphoglycerate mutase-like | 0.000003333 | DIRECT |
| beta-Roll | 0.000003838 | DIRECT |
| PUG domain-like | 0.00000532 | DIRECT |
| DNA clamp | 0.00001607 | DIRECT |
| CBD9-like | 0.00001607 | DIRECT |
| HCP-like | 0.00001991 | DIRECT |
| HIT/MYND zinc finger-like | 0.00002349 | DIRECT |
| DEK C-terminal domain | 0.00002356 | DIRECT |
| PH0987 N-terminal domain-like | 0.00007897 | DIRECT |
| FnI-like domain | 0.0002005 | DIRECT |
| Chromo domain-like | 0.0002587 | DIRECT |
| Barwin-like endoglucanases | 0.0002835 | DIRECT |
| SRCR-like | 0.0007115 | DIRECT |
| Hedgehog/intein (Hint) domain | 0.0009016 | DIRECT |
| Ricin B-like lectins | 0.001455 | INHERITED FROM: Alpha-galactosidase || Hydrolyzing N-glycosyl compounds || rRNA N-glycosylase || Glycosylases |
| Cell wall binding repeat | 0.001471 | INHERITED FROM: In linear amides || N-acetylmuramoyl-L-alanine amidase || Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds || Glycosylases |
| WD40 repeat-like | 0.00165 | INHERITED FROM: Acting on ester bonds || Poly(A)-specific ribonuclease || Exoribonucleases producing 5'-phosphomonoesters || Methylated diphthine methylhydrolase |
| Ras GEF | 0.0019 | INHERITED FROM: Phosphoric diester hydrolases || Phosphoinositide phospholipase C || Acting on ester bonds |
| SAP domain | 0.002503 | INHERITED FROM: Acting on acid anhydrides || Acting on ATP; involved in cellular and subcellular movement || DNA helicase |
| GTPase activation domain, GAP | 0.003596 | INHERITED FROM: Phosphoinositide 5-phosphatase || Acting on ester bonds || Inositol-polyphosphate 5-phosphatase || Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase || Phosphoric monoester hydrolases |
| Integrin alpha N-terminal domain | 0.003596 | INHERITED FROM: Phosphoric diester hydrolases || Acting on ester bonds || Glycosylphosphatidylinositol phospholipase D |
| FAH | 0.005158 | INHERITED FROM: Fumarylacetoacetase || Acting on carbon-carbon bonds || Acylpyruvate hydrolase |
| PX domain | 0.006395 | INHERITED FROM: Phosphoric diester hydrolases || Acting on ester bonds || Phospholipase D |
| PIN domain-like | 0.007118 | INHERITED FROM: Ribonuclease P || Acting on ester bonds || Exodeoxyribonuclease (lambda-induced) || Endoribonucleases producing 5'-phosphomonoesters |
| F-box domain | 0.007836 | INHERITED FROM: Acting on acid anhydrides || Acting on ATP; involved in cellular and subcellular movement || DNA helicase |
| Rhodanese/Cell cycle control phosphatase | 0.01034 | INHERITED FROM: Acting on ester bonds || Protein-tyrosine-phosphatase || Protein-serine/threonine phosphatase || Omega peptidases || Phosphoric monoester hydrolases || Ubiquitinyl hydrolase 1 |
| C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase | 0.01203 | INHERITED FROM: Acting on ester bonds || 6-phosphogluconolactonase |
| RNA-binding domain, RBD | 0.01276 | INHERITED FROM: Phosphoinositide 5-phosphatase || RNA helicase || Acting on acid anhydrides || Poly(A)-specific ribonuclease || Exoribonucleases producing 5'-phosphomonoesters || Acting on ATP; involved in cellular and subcellular movement |
| Chaperone J-domain | 0.01954 | INHERITED FROM: Acting on ester bonds || Protein-tyrosine-phosphatase || Phosphoric monoester hydrolases |
| MIT domain | 0.01972 | INHERITED FROM: Vesicle-fusing ATPase || Acting on acid anhydrides || Acting on ATP; involved in cellular and subcellular movement |
| DNA-glycosylase | 0.02035 | INHERITED FROM: Adenine glycosylase || Hydrolyzing N-glycosyl compounds || Glycosylases || DNA-3-methyladenine glycosylase II |
| Second domain of FERM | 0.02603 | INHERITED FROM: Acting on ester bonds || Protein-tyrosine-phosphatase || Phosphoric monoester hydrolases |
| Duplicated hybrid motif | 0.02897 | INHERITED FROM: Metalloendopeptidases || Acting on peptide bonds (peptidases) || Lysostaphin |
| PHP domain-like | 0.04137 | INHERITED FROM: Ribonuclease P || Acting on ester bonds || Histidinol-phosphatase || Endoribonucleases producing 5'-phosphomonoesters || 3',5'-nucleoside bisphosphate phosphatase |
| Homing endonucleases | 0.0687 | INHERITED FROM: Acting on acid anhydrides || Acting on ATP; involved in cellular and subcellular movement || DNA helicase |
| SMAD/FHA domain | 0.07298 | INHERITED FROM: Exodeoxyribonucleases producing 3'-phosphomonoesters || Exodeoxyribonucleases producing 5'-phosphomonoesters || Acting on ester bonds || Adenosine-5'-diphospho-5'-(DNA) diphosphatase || DNA-3'-diphospho-5'-guanosine diphosphatase |
| Ran binding protein zinc finger-like | 0.08247 | INHERITED FROM: Acting on peptide bonds (peptidases) || Omega peptidases || Ubiquitinyl hydrolase 1 |
| TATA-box binding protein-like | 0.09636 | INHERITED FROM: Hydrolyzing N-glycosyl compounds || Glycosylases || DNA-3-methyladenine glycosylase II |
| YrdC/RibB | 0.1001 | INHERITED FROM: GTP cyclohydrolase II || In cyclic amidines || Acting on carbon-nitrogen bonds, other than peptide bonds |
| CRAL/TRIO domain | 0.1352 | INHERITED FROM: Protein-tyrosine-phosphatase || Phosphoric monoester hydrolases |
| TRAF domain-like | 0.2215 | INHERITED FROM: Meprin A || Metalloendopeptidases || Acting on peptide bonds (peptidases) || Omega peptidases || Meprin B || Ubiquitinyl hydrolase 1 |
| HMA, heavy metal-associated domain | 0.2215 | INHERITED FROM: Acting on acid anhydrides || Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| NTF2-like | 0.2321 | INHERITED FROM: RNA helicase || Sucrose-phosphate phosphatase || Phosphoric monoester hydrolases |
| HSP20-like chaperones | 0.2529 | INHERITED FROM: Omega peptidases || Ubiquitinyl hydrolase 1 |
| Ankyrin repeat | 0.3215 | INHERITED FROM: Asparaginase || Lysophospholipase || 1-alkyl-2-acetylglycerophosphocholine esterase || Phosphoric diester hydrolases || In linear amides || NAD(+) diphosphatase || Glutaminase || Adenosinetriphosphatase |
| Non-globular alpha+beta subunits of globular proteins | 0.5386 | INHERITED FROM: Protein-tyrosine-phosphatase || Phosphoric monoester hydrolases |
| post-AAA+ oligomerization domain-like | 0.5818 | INHERITED FROM: In phosphorus-containing anhydrides || Adenosinetriphosphatase |
| PUA domain-like | 0.6612 | INHERITED FROM: Serine endopeptidases || Acting on peptide bonds (peptidases) || Endopeptidase La |
| FYVE/PHD zinc finger | 0.7012 | INHERITED FROM: Acting on acid anhydrides || Protein-tyrosine-phosphatase || Acting on ATP; involved in cellular and subcellular movement || Phosphatidylinositol-3-phosphatase || Phosphoric monoester hydrolases || DNA helicase || Phosphatidylinositol-3,5-bisphosphate 3-phosphatase |
| ARM repeat | 0.7108 | INHERITED FROM: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase || Ether hydrolases || Acting on ether bonds || Aminopeptidase B || Omega peptidases || Ubiquitinyl hydrolase 1 |
| Prokaryotic type I DNA topoisomerase | 0.7516 | INHERITED FROM: Acting on acid anhydrides || Acting on ATP; involved in cellular and subcellular movement || DNA helicase |
| Heme oxygenase-like | 0.8238 | INHERITED FROM: Aminopyrimidine aminohydrolase || In other compounds || Acting on carbon-nitrogen bonds, other than peptide bonds |
| Bromodomain | 0.8387 | INHERITED FROM: Adenosinetriphosphatase |
| Kelch motif | 0.8793 | INHERITED FROM: Protein-serine/threonine phosphatase || Phosphoric monoester hydrolases |
| L30e-like | 0.9309 | INHERITED FROM: Ribonuclease P || Endoribonucleases producing 5'-phosphomonoesters |
| Ribonuclease Rh-like | 0.9422 | INHERITED FROM: Serine endopeptidases || RNA helicase || Nucleoside-triphosphate phosphatase || In phosphorus-containing anhydrides || Pestivirus NS3 polyprotein peptidase || Acting on ATP; involved in cellular and subcellular movement |
| beta-carbonic anhydrase, cab | 0.9598 | INHERITED FROM: Carbon disulfide hydrolase || Acting on carbon-sulfur bonds |
| Quinoprotein alcohol dehydrogenase-like | 0.9853 | INHERITED FROM: Poly(A)-specific ribonuclease || Exoribonucleases producing 5'-phosphomonoesters |
| CCCH zinc finger | 0.9987 | INHERITED FROM: RNA helicase |
| Amidase signature (AS) enzymes | 1 | INHERITED FROM: In linear amides || Allophanate hydrolase || Amidase || Fatty acid amide hydrolase |
| UDP-Glycosyltransferase/glycogen phosphorylase | 1 | INHERITED FROM: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) || Trehalose-phosphatase |
| Phosphoenolpyruvate/pyruvate domain | 1 | INHERITED FROM: (3S)-malyl-CoA thioesterase |
| PreATP-grasp domain | 1 | INHERITED FROM: Dihydroorotase |
| SH2 domain | 1 | INHERITED FROM: Phosphoric diester hydrolases || Phosphoinositide 5-phosphatase || Phosphoinositide phospholipase C || Acting on ester bonds || Protein-tyrosine-phosphatase || Inositol-polyphosphate 5-phosphatase || Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase || Phosphoric monoester hydrolases |
| RmlC-like cupins | 1 | INHERITED FROM: (S)-ureidoglycine aminohydrolase |
| PLP-dependent transferases | 1 | INHERITED FROM: Kynureninase || Acting on carbon-carbon bonds |
| ACP-like | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Ether hydrolases || Acting on ether bonds || Thiolester hydrolases || Isochorismatase |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 1 | INHERITED FROM: Deoxyribonuclease V || Endodeoxyribonucleases producing 5'-phosphomonoesters |
| Growth factor receptor domain | 1 | INHERITED FROM: Serine endopeptidases || Furin || Acting on peptide bonds (peptidases) || Coagulation factor Xa |
| Cyclophilin-like | 1 | INHERITED FROM: In cyclic amides || 5-oxoprolinase (ATP-hydrolyzing) |
| PYP-like sensor domain (PAS domain) | 1 | INHERITED FROM: Phosphoric diester hydrolases || 3',5'-cyclic-AMP phosphodiesterase || Cyclic-guanylate-specific phosphodiesterase |
| PHP14-like | 1 | INHERITED FROM: Phosphohistidine phosphatase || Acting on phosphorus-nitrogen bonds |
| Terpenoid synthases | 1 | INHERITED FROM: Geranyl diphosphate diphosphatase || Diphosphoric monoester hydrolases |
| SAM/Pointed domain | 1 | INHERITED FROM: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase || Hydrolyzing N-glycosyl compounds || Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase |
| Thioredoxin-like | 1 | INHERITED FROM: Phospholipase A(2) |
| Immunoglobulin | 1 | INHERITED FROM: Acting on ester bonds || Protein-tyrosine-phosphatase || Phosphoric monoester hydrolases |
| Nucleotide cyclase | 1 | INHERITED FROM: Phosphoric diester hydrolases || Cyclic-guanylate-specific phosphodiesterase |
| Nucleotidyltransferase | 1 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Diphosphoric monoester hydrolases |
| Calcium ATPase, transmembrane domain M | 1 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Thiolester hydrolases |
| Formyltransferase | 1 | INHERITED FROM: Formyltetrahydrofolate deformylase |
| Dihydrofolate reductase-like | 1 | INHERITED FROM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase || In cyclic amidines || Acting on carbon-nitrogen bonds, other than peptide bonds |
| TGS-like | 1 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Diphosphoric monoester hydrolases |
| Inosine monophosphate dehydrogenase (IMPDH) | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase |
| RING/U-box | 1 | INHERITED FROM: Omega peptidases || Ubiquitinyl hydrolase 1 |
| Periplasmic binding protein-like II | 1 | INHERITED FROM: Alkaline phosphatase |
| Bet v1-like | 1 | INHERITED FROM: Thiolester hydrolases || Acetyl-CoA hydrolase |
| Terpenoid cyclases/Protein prenyltransferases | 1 | INHERITED FROM: Geranyl diphosphate diphosphatase || Diphosphoric monoester hydrolases |
| LuxS/MPP-like metallohydrolase | 1 | INHERITED FROM: Metalloendopeptidases || Nardilysin || Acting on peptide bonds (peptidases) || Mitochondrial processing peptidase || Pitrilysin || Insulysin |
| TPR-like | 1 | INHERITED FROM: Protein-serine/threonine phosphatase || Phosphoric monoester hydrolases |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: In cyclic amides || Dihydroorotase |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | INHERITED FROM: Polynucleotide 5'-phosphatase |
| ADP-ribosylation | 1 | INHERITED FROM: Hydrolyzing N-glycosyl compounds || NAD(+) glycohydrolase |
| AraD/HMP-PK domain-like | 1 | INHERITED FROM: Acireductone synthase |
| Actin-like ATPase domain | 1 | INHERITED FROM: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) || Guanosine-5'-triphosphate,3'-diphosphate diphosphatase || In phosphorus-containing anhydrides || Exopolyphosphatase || Adenosinetriphosphatase || Non-chaperonin molecular chaperone ATPase |
| NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Maltose-6'-phosphate glucosidase || UDP-sulfoquinovose synthase || Acting on ether bonds || Alpha-N-acetylgalactosaminidase || Thioether and trialkylsulfonium hydrolases || In cyclic amidines || Methenyltetrahydrofolate cyclohydrolase || Acting on carbon-nitrogen bonds, other than peptide bonds |
| Cupredoxins | 1 | INHERITED FROM: In linear amidines || Protein-arginine deiminase |
| ADC-like | 1 | INHERITED FROM: Vesicle-fusing ATPase || Acting on ATP; involved in cellular and subcellular movement |
| Thiamin diphosphate-binding fold (THDP-binding) | 1 | INHERITED FROM: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) || Acting on carbon-carbon bonds |
| SH3-domain | 1 | INHERITED FROM: Phosphoric diester hydrolases || Phosphoinositide phospholipase C |
| Clavaminate synthase-like | 1 | INHERITED FROM: RNA helicase |
| DHS-like NAD/FAD-binding domain | 1 | INHERITED FROM: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) || Acting on carbon-carbon bonds |
| GroES-like | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase |
| Nucleic acid-binding proteins | 1 | INHERITED FROM: Exoribonuclease II || Acting on acid anhydrides || Ribonuclease E || Exoribonucleases producing 5'-phosphomonoesters || Acting on ATP; involved in cellular and subcellular movement || DNA helicase |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Acting on ester bonds || Palmitoyl-CoA hydrolase || Thiolester hydrolases || 1,4-dihydroxy-2-naphthoyl-CoA hydrolase |
| WW domain | 1 | INHERITED FROM: RNA helicase || Acting on ATP; involved in cellular and subcellular movement |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | INHERITED FROM: 1-aminocyclopropane-1-carboxylate deaminase || In other compounds |
| L domain-like | 1 | INHERITED FROM: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase || Hydrolyzing N-glycosyl compounds || Acting on ester bonds || Protein-serine/threonine phosphatase || Poly(A)-specific ribonuclease || Exoribonucleases producing 5'-phosphomonoesters |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | INHERITED FROM: Adenosinetriphosphatase |
| LDH C-terminal domain-like | 1 | INHERITED FROM: Maltose-6'-phosphate glucosidase || Alpha-galactosidase || 6-phospho-beta-glucosidase || Alpha-glucosidase || Galacturonan 1,4-alpha-galacturonidase |
| Aspartate/ornithine carbamoyltransferase | 1 | INHERITED FROM: Dihydroorotase |
| Acyl-CoA N-acyltransferases (Nat) | 1 | INHERITED FROM: Protein O-GlcNAcase |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || RNA helicase || Nucleoside-triphosphate phosphatase || ADP-ribose 1''-phosphate phosphatase || Polynucleotide 5'-phosphatase || SARS coronavirus main proteinase || Flavivirin || Endothelin-converting enzyme 1 |
| Thiolase-like | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Palmitoyl-CoA hydrolase || Thiolester hydrolases || Acetyl-CoA hydrolase |
| Carbonic anhydrase | 1 | INHERITED FROM: Protein-tyrosine-phosphatase |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | INHERITED FROM: In cyclic amides || Dihydroorotase |
| Alkaline phosphatase-like | 1 | INHERITED FROM: Sulfuric ester hydrolases || Phosphodiesterase I || Phosphoric diester hydrolases || Acting on carbon-phosphorus bonds || Alkaline phosphatase || Acting on ester bonds || Alkylglycerophosphoethanolamine phosphodiesterase || Phosphonoacetate hydrolase || Bis(5'-adenosyl)-triphosphatase || Glycerophosphocholine cholinephosphodiesterase || Nucleotide diphosphatase |
| FMT C-terminal domain-like | 1 | INHERITED FROM: DNA-3-methyladenine glycosylase II |
| Calcium ATPase, transduction domain A | 1 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
| ACT-like | 1 | INHERITED FROM: Phosphoserine phosphatase || Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Diphosphoric monoester hydrolases || Formyltetrahydrofolate deformylase |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Aminopeptidase/glucanase lid domain | 0 | Direct |
| PKD domain | 0 | Direct |
| Galactose-binding domain-like | 0 | Direct |
| Lysozyme-like | 0 | Direct |
| Nucleoside hydrolase | 0 | Direct |
| Glutaminase/Asparaginase | 0 | Direct |
| N-terminal Zn binding domain of HIV integrase | 0 | Direct |
| AN1-like Zinc finger | 0 | Direct |
| "Winged helix" DNA-binding domain | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Methylglyoxal synthase-like | 0 | Direct |
| Retrovirus capsid dimerization domain-like | 0 | Direct |
| Soluble domain of poliovirus core protein 3a | 0 | Direct |
| Voltage-gated potassium channels | 0 | Direct |
| Ribonuclease H-like | 0 | Direct |
| PAZ domain | 0 | Direct |
| DUSP-like | 0 | Direct |
| LD-carboxypeptidase A C-terminal domain-like | 0 | Direct |
| Carboxypeptidase regulatory domain-like | 0 | Direct |
| ClpP/crotonase | 0 | Direct |
| Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
| Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Peptidyl-tRNA hydrolase-like | 0 | Direct |
| Flavivirus capsid protein C | 0 | Direct |
| ComB-like | 0 | Direct |
| Nitrous oxide reductase, N-terminal domain | 0 | Direct |
| CinA-like | 0 | Direct |
| Sec-C motif | 0 | Direct |
| Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
| HisI-like | 0 | Direct |
| ADP-ribosylglycohydrolase | 0 | Direct |
| Toprim domain | 0 | Direct |
| Peptide deformylase | 0 | Direct |
| (Phosphotyrosine protein) phosphatases II | 0 | Direct |
| Penicillin-binding protein associated domain | 0 | Direct |
| Carbon-nitrogen hydrolase | 0 | Direct |
| Glycoside hydrolase/deacetylase | 0 | Direct |
| Invasin/intimin cell-adhesion fragments | 0 | Direct |
| Fumarylacetoacetate hydrolase, FAH, N-terminal domain | 0 | Direct |
| Archaeal IMP cyclohydrolase PurO | 0 | Direct |
| Kazal-type serine protease inhibitors | 0 | Direct |
| EF-G C-terminal domain-like | 0 | Direct |
| Glycosyl hydrolase domain | 0 | Direct |
| Uracil-DNA glycosylase-like | 0 | Direct |
| Putative cyclase | 0 | Direct |
| Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
| Phage fibre proteins | 0 | Direct |
| EGF/Laminin | 0 | Direct |
| Penicillin binding protein dimerisation domain | 0 | Direct |
| Trefoil | 0 | Direct |
| Sec63 N-terminal domain-like | 0 | Direct |
| Carbohydrate phosphatase | 0 | Direct |
| Cellulose-binding domain | 0 | Direct |
| Urease, gamma-subunit | 0 | Direct |
| Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
| Apyrase | 0 | Direct |
| Cellulose docking domain, dockering | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Spermadhesin, CUB domain | 0 | Direct |
| Initiation factor IF2/eIF5b, domain 3 | 0 | Direct |
| Transferrin receptor-like dimerisation domain | 0 | Direct |
| DPP6 N-terminal domain-like | 0 | Direct |
| Hyaluronidase post-catalytic domain-like | 0 | Direct |
| Dipeptidyl peptidase I (cathepsin C), exclusion domain | 0 | Direct |
| X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain | 0 | Direct |
| Herpes virus serine proteinase, assemblin | 0 | Direct |
| Viral leader polypeptide zinc finger | 0 | Direct |
| CNF1/YfiH-like putative cysteine hydrolases | 0 | Direct |
| SEA domain | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| Clostridium neurotoxins, "coiled-coil" domain | 0 | Direct |
| N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
| SGNH hydrolase | 0 | Direct |
| Peptidyl-tRNA hydrolase II | 0 | Direct |
| Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
| Sortase | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| L9 N-domain-like | 0 | Direct |
| Cdc48 domain 2-like | 0 | Direct |
| Calpain large subunit, middle domain (domain III) | 0 | Direct |
| Replicase NSP9 | 0 | Direct |
| all-alpha NTP pyrophosphatases | 0 | Direct |
| Six-hairpin glycosidases | 0 | Direct |
| Creatinase/prolidase N-terminal domain | 0 | Direct |
| Methenyltetrahydromethanopterin cyclohydrolase | 0 | Direct |
| Zn-dependent exopeptidases | 0 | Direct |
| Cap-Gly domain | 0 | Direct |
| Acid proteases | 0 | Direct |
| SARS Nsp1-like | 0 | Direct |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
| Kringle-like | 0 | Direct |
| Rof/RNase P subunit-like | 0 | Direct |
| R3H domain | 0 | Direct |
| Concanavalin A-like lectins/glucanases | 0 | Direct |
| Acetamidase/Formamidase-like | 0 | Direct |
| DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
| Coronavirus NSP8-like | 0 | Direct |
| Coronavirus NSP10-like | 0 | Direct |
| CheY-like | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
| DNase I-like | 0 | Direct |
| Rap30/74 interaction domains | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Creatininase | 0 | Direct |
| LigT-like | 0 | Direct |
| Dcp2 domain-like | 0 | Direct |
| FabD/lysophospholipase-like | 0 | Direct |
| Carbohydrate binding domain | 0 | Direct |
| Thermostable phytase (3-phytase) | 0 | Direct |
| Metallo-dependent hydrolases | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| DNA primase core | 0 | Direct |
| TMV-like viral coat proteins | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Outer membrane phospholipase A (OMPLA) | 0 | Direct |
| Sulfolobus fructose-1,6-bisphosphatase-like | 0 | Direct |
| C-terminal domain of PLC-beta | 0 | Direct |
| Formate/glycerate dehydrogenase catalytic domain-like | 0 | Direct |
| EndoU-like | 0 | Direct |
| alpha/beta-Hydrolases | 0 | Direct |
| Cytidine deaminase-like | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| His-Me finger endonucleases | 0 | Direct |
| Phospholipase A2, PLA2 | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Coronavirus NSP7-like | 0 | Direct |
| LmbE-like | 0 | Direct |
| STI-like | 0 | Direct |
| mRNA decapping enzyme DcpS N-terminal domain | 0 | Direct |
| Nudix | 0 | Direct |
| Inorganic pyrophosphatase | 0 | Direct |
| P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
| Metallo-dependent phosphatases | 0 | Direct |
| Metallo-hydrolase/oxidoreductase | 0 | Direct |
| Methylesterase CheB, C-terminal domain | 0 | Direct |
| Plant lectins/antimicrobial peptides | 0 | Direct |
| Viral protein domain | 0 | Direct |
| Composite domain of metallo-dependent hydrolases | 0 | Direct |
| GLA-domain | 0 | Direct |
| Isochorismatase-like hydrolases | 0 | Direct |
| beta-lactamase/transpeptidase-like | 0 | Direct |
| Transthyretin (synonym: prealbumin) | 0 | Direct |
| CRAL/TRIO N-terminal domain | 0 | Direct |
| HIT-like | 0 | Direct |
| PH domain-like | 0 | Direct |
| AlbA-like | 0 | Direct |
| N-terminal domain of DnaB helicase | 0 | Direct |
| Bacterial exopeptidase dimerisation domain | 0 | Direct |
| PP2C-like | 0 | Direct |
| Putative isomerase YbhE | 0 | Direct |
| Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) | 0 | Direct |
| HRDC-like | 0 | Direct |
| CbiG N-terminal domain-like | 0 | Direct |
| Retroviral matrix proteins | 0 | Direct |
| Families 57/38 glycoside transferase middle domain | 0 | Direct |
| Pentein | 0 | Direct |
| Galactose mutarotase-like | 0 | Direct |
| Hemopexin-like domain | 0 | Direct |
| Cystatin/monellin | 0 | Direct |
| BRK domain-like | 0 | Direct |
| 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | Direct |
| Peptidyl-tRNA hydrolase domain-like | 0 | Direct |
| Influenza hemagglutinin (stalk) | 0 | Direct |
| Arginase/deacetylase | 0 | Direct |
| cAMP-binding domain-like | 0 | Direct |
| Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
| DTD-like | 0 | Direct |
| CobE/GbiG C-terminal domain-like | 0 | Direct |
| DNA-binding domain of retroviral integrase | 0 | Direct |
| DHH phosphoesterases | 0 | Direct |
| SurE-like | 0 | Direct |
| C-terminal domain of Ku80 | 0 | Direct |
| Cysteine proteinases | 0 | Direct |
| Acylphosphatase/BLUF domain-like | 0 | Direct |
| CYTH-like phosphatases | 0 | Direct |
| HybD-like | 0 | Direct |
| Holliday junction resolvase RusA | 0 | Direct |
| Type I dockerin domain | 0 | Direct |
| TSP-1 type 1 repeat | 0 | Direct |
| D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
| Hedgehog/DD-peptidase | 0 | Direct |
| Glycosyl hydrolases family 6, cellulases | 0 | Direct |
| beta-Galactosidase/glucuronidase domain | 0 | Direct |
| Invertebrate chitin-binding proteins | 0 | Direct |
| MCP/YpsA-like | 0 | Direct |
| Beta-galactosidase LacA, domain 3 | 0 | Direct |
| Toll/Interleukin receptor TIR domain | 0 | Direct |
| S13-like H2TH domain | 0 | Direct |
| AF0625-like | 0 | Direct |
| Macro domain-like | 0 | Direct |
| Protease propeptides/inhibitors | 0 | Direct |
| Dextranase, N-terminal domain | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| (Trans)glycosidases | 0 | Direct |
| Trypsin-like serine proteases | 0 | Direct |
| Type X cellulose binding domain, CBDX | 0 | Direct |
| LexA/Signal peptidase | 0 | Direct |
| RibA-like | 0 | Direct |
| Urease, beta-subunit | 0 | Direct |
| HAD-like | 0 | Direct |
| beta-N-acetylhexosaminidase-like domain | 0 | Direct |
| Saposin | 0 | Direct |
| Xylose isomerase-like | 0 | Direct |
| Viral glycoprotein, central and dimerisation domains | 0 | Direct |
| Bacterial GAP domain | 0 | Direct |
| Anthrax protective antigen | 0 | Direct |
| Peptidase/esterase 'gauge' domain | 0 | Direct |
| Ribosome inactivating proteins (RIP) | 0 | Direct |
| SpoIIaa-like | 0 | Direct |
| dUTPase-like | 0 | Direct |
| Sialidases | 0 | Direct |
| ssDNA viruses | 0 | Direct |
| Arabinanase/levansucrase/invertase | 0 | Direct |
| Chitinase insertion domain | 0 | Direct |
| OMPT-like | 0 | Direct |
| Complement control module/SCR domain | 0 | Direct |
| XseB-like | 0 | Direct |
| PLC-like phosphodiesterases | 0 | Direct |
| NSP3A-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Phospholipase C/P1 nuclease | 0 | Direct |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | Direct |
| Caspase-like | 0 | Direct |
| Origin of replication-binding domain, RBD-like | 0 | Direct |
| Creatinase/aminopeptidase | 0 | Direct |
| Beta-D-glucan exohydrolase, C-terminal domain | 0 | Direct |
| Positive stranded ssRNA viruses | 0 | Direct |
| AbfB domain | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| ITPase-like | 0 | Direct |
| PDZ domain-like | 0 | Direct |
| Autotransporter | 0 | Direct |
| Leukotriene A4 hydrolase N-terminal domain | 0 | Direct |
| Rnp2-like | 0 | Direct |
| Carbohydrate-binding domain | 0 | Direct |
| N-terminal domain of MutM-like DNA repair proteins | 0 | Direct |
| Somatomedin B domain | 0 | Direct |
| Collagen-binding domain | 0 | Direct |
| Prokaryotic SH3-related domain | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Plant invertase/pectin methylesterase inhibitor | 0 | Direct |
| RuvA domain 2-like | 0 | Direct |
| Purple acid phosphatase, N-terminal domain | 0 | Direct |
| PGBD-like | 0 | Direct |
| E set domains | 1.78e-16 | Direct |
| HD-domain/PDEase-like | 1.78e-16 | Direct |
| vWA-like | 0.000000000000002809 | Direct |
| LysM domain | 0.00000000000002358 | Direct |
| Calcium-dependent phosphotriesterase | 0.00000000000003215 | Direct |
| EF-hand | 0.00000000000004279 | Direct |
| Translation proteins | 0.00000000000004382 | Direct |
| Microbial ribonucleases | 0.00000000000007573 | Direct |
| Purine and uridine phosphorylases | 0.0000000000002683 | Direct |
| EAL domain-like | 0.0000000000003752 | Direct |
| Ribosomal protein S5 domain 2-like | 0.000000000002328 | Direct |
| Tudor/PWWP/MBT | 0.00000000001395 | Direct |
| Phosphotyrosine protein phosphatases I | 0.00000000002229 | Direct |
| Staphylococcal nuclease | 0.0000000005812 | Direct |
| Ubiquitin-like | 0.0000000006239 | Direct |
| UBA-like | 0.000000001634 | Direct |
| DEATH domain | 0.000000009677 | Direct |
| PA domain | 0.00000001122 | Direct |
| Hairpin loop containing domain-like | 0.00000001244 | Direct |
| YjgF-like | 0.00000001816 | Direct |
| GAF domain-like | 0.00000002764 | Direct |
| LDL receptor-like module | 0.00000005715 | Direct |
| Phospholipase D/nuclease | 0.00000006593 | Direct |
| Fibronectin type III | 0.0000002224 | Direct |
| NagB/RpiA/CoA transferase-like | 0.0000002904 | Direct |
| Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.0000003132 | Direct |
| Starch-binding domain-like | 0.0000008391 | Direct |
| N-(deoxy)ribosyltransferase-like | 0.000001362 | Direct |
| Phosphoglycerate mutase-like | 0.000003333 | Direct |
| beta-Roll | 0.000003838 | Direct |
| PUG domain-like | 0.00000532 | Direct |
| DNA clamp | 0.00001607 | Direct |
| CBD9-like | 0.00001607 | Direct |
| HCP-like | 0.00001991 | Direct |
| HIT/MYND zinc finger-like | 0.00002349 | Direct |
| DEK C-terminal domain | 0.00002356 | Direct |
| PH0987 N-terminal domain-like | 0.00007897 | Direct |
| FnI-like domain | 0.0002005 | Direct |
| Chromo domain-like | 0.0002587 | Direct |
| Barwin-like endoglucanases | 0.0002835 | Direct |
| SRCR-like | 0.0007115 | Direct |
| Hedgehog/intein (Hint) domain | 0.0009016 | Direct |
| Ricin B-like lectins | 0.001455 | Inherited |
| Cell wall binding repeat | 0.001471 | Inherited |
| WD40 repeat-like | 0.00165 | Inherited |
| Ras GEF | 0.0019 | Inherited |
| SAP domain | 0.002503 | Inherited |
| GTPase activation domain, GAP | 0.003596 | Inherited |
| Integrin alpha N-terminal domain | 0.003596 | Inherited |
| FAH | 0.005158 | Inherited |
| PX domain | 0.006395 | Inherited |
| PIN domain-like | 0.007118 | Inherited |
| F-box domain | 0.007836 | Inherited |
| Rhodanese/Cell cycle control phosphatase | 0.01034 | Inherited |
| C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase | 0.01203 | Inherited |
| RNA-binding domain, RBD | 0.01276 | Inherited |
| Chaperone J-domain | 0.01954 | Inherited |
| MIT domain | 0.01972 | Inherited |
| DNA-glycosylase | 0.02035 | Inherited |
| Second domain of FERM | 0.02603 | Inherited |
| Duplicated hybrid motif | 0.02897 | Inherited |
| PHP domain-like | 0.04137 | Inherited |
| Homing endonucleases | 0.0687 | Inherited |
| SMAD/FHA domain | 0.07298 | Inherited |
| Ran binding protein zinc finger-like | 0.08247 | Inherited |
| TATA-box binding protein-like | 0.09636 | Inherited |
| YrdC/RibB | 0.1001 | Inherited |
| CRAL/TRIO domain | 0.1352 | Inherited |
| TRAF domain-like | 0.2215 | Inherited |
| HMA, heavy metal-associated domain | 0.2215 | Inherited |
| NTF2-like | 0.2321 | Inherited |
| HSP20-like chaperones | 0.2529 | Inherited |
| Ankyrin repeat | 0.3215 | Inherited |
| Non-globular alpha+beta subunits of globular proteins | 0.5386 | Inherited |
| post-AAA+ oligomerization domain-like | 0.5818 | Inherited |
| PUA domain-like | 0.6612 | Inherited |
| FYVE/PHD zinc finger | 0.7012 | Inherited |
| ARM repeat | 0.7108 | Inherited |
| Prokaryotic type I DNA topoisomerase | 0.7516 | Inherited |
| Heme oxygenase-like | 0.8238 | Inherited |
| Bromodomain | 0.8387 | Inherited |
| Kelch motif | 0.8793 | Inherited |
| L30e-like | 0.9309 | Inherited |
| Ribonuclease Rh-like | 0.9422 | Inherited |
| beta-carbonic anhydrase, cab | 0.9598 | Inherited |
| Quinoprotein alcohol dehydrogenase-like | 0.9853 | Inherited |
| CCCH zinc finger | 0.9987 | Inherited |
| Amidase signature (AS) enzymes | 1 | Inherited |
| UDP-Glycosyltransferase/glycogen phosphorylase | 1 | Inherited |
| Phosphoenolpyruvate/pyruvate domain | 1 | Inherited |
| PreATP-grasp domain | 1 | Inherited |
| SH2 domain | 1 | Inherited |
| RmlC-like cupins | 1 | Inherited |
| PLP-dependent transferases | 1 | Inherited |
| ACP-like | 1 | Inherited |
| Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 1 | Inherited |
| Growth factor receptor domain | 1 | Inherited |
| Cyclophilin-like | 1 | Inherited |
| PYP-like sensor domain (PAS domain) | 1 | Inherited |
| PHP14-like | 1 | Inherited |
| Terpenoid synthases | 1 | Inherited |
| SAM/Pointed domain | 1 | Inherited |
| Thioredoxin-like | 1 | Inherited |
| Immunoglobulin | 1 | Inherited |
| Nucleotide cyclase | 1 | Inherited |
| Nucleotidyltransferase | 1 | Inherited |
| Calcium ATPase, transmembrane domain M | 1 | Inherited |
| Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | Inherited |
| Formyltransferase | 1 | Inherited |
| Dihydrofolate reductase-like | 1 | Inherited |
| TGS-like | 1 | Inherited |
| Inosine monophosphate dehydrogenase (IMPDH) | 1 | Inherited |
| RING/U-box | 1 | Inherited |
| Periplasmic binding protein-like II | 1 | Inherited |
| Bet v1-like | 1 | Inherited |
| Terpenoid cyclases/Protein prenyltransferases | 1 | Inherited |
| LuxS/MPP-like metallohydrolase | 1 | Inherited |
| TPR-like | 1 | Inherited |
| Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
| DNA ligase/mRNA capping enzyme, catalytic domain | 1 | Inherited |
| ADP-ribosylation | 1 | Inherited |
| AraD/HMP-PK domain-like | 1 | Inherited |
| Actin-like ATPase domain | 1 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
| Cupredoxins | 1 | Inherited |
| ADC-like | 1 | Inherited |
| Thiamin diphosphate-binding fold (THDP-binding) | 1 | Inherited |
| SH3-domain | 1 | Inherited |
| Clavaminate synthase-like | 1 | Inherited |
| DHS-like NAD/FAD-binding domain | 1 | Inherited |
| GroES-like | 1 | Inherited |
| Nucleic acid-binding proteins | 1 | Inherited |
| Thioesterase/thiol ester dehydrase-isomerase | 1 | Inherited |
| WW domain | 1 | Inherited |
| Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | Inherited |
| L domain-like | 1 | Inherited |
| ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | Inherited |
| LDH C-terminal domain-like | 1 | Inherited |
| Aspartate/ornithine carbamoyltransferase | 1 | Inherited |
| Acyl-CoA N-acyltransferases (Nat) | 1 | Inherited |
| S-adenosyl-L-methionine-dependent methyltransferases | 1 | Inherited |
| Thiolase-like | 1 | Inherited |
| Carbonic anhydrase | 1 | Inherited |
| Carbamoyl phosphate synthetase, small subunit N-terminal domain | 1 | Inherited |
| Alkaline phosphatase-like | 1 | Inherited |
| FMT C-terminal domain-like | 1 | Inherited |
| Calcium ATPase, transduction domain A | 1 | Inherited |
| ACT-like | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (SPEC level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
101596,51126
101596 - Dextranase, N-terminal domain
51126 - Pectin lyase-like | 0 | DIRECT |
57850,54001
57850 - RING/U-box
54001 - Cysteine proteinases | 0 | DIRECT |
102860,54197
102860 - mRNA decapping enzyme DcpS N-terminal domain
54197 - HIT-like | 0 | DIRECT |
82671,57424
82671 - SEA domain
57424 - LDL receptor-like module | 0 | DIRECT |
56784,54427
56784 - HAD-like
54427 - NTF2-like | 0 | DIRECT |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | DIRECT |
53639,56784
53639 - AraD/HMP-PK domain-like
56784 - HAD-like | 0 | DIRECT |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49265,51445
49265 - Fibronectin type III
51445 - (Trans)glycosidases | 0 | DIRECT |
55486,51120
55486 - Metalloproteases ("zincins"), catalytic domain
51120 - beta-Roll | 0 | DIRECT |
51445,63446
51445 - (Trans)glycosidases
63446 - Type I dockerin domain | 0 | DIRECT |
49599,54001
49599 - TRAF domain-like
54001 - Cysteine proteinases | 0 | DIRECT |
53098,54928
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | DIRECT |
52743,52025
52743 - Subtilisin-like
52025 - PA domain | 0 | DIRECT |
49899,57180
49899 - Concanavalin A-like lectins/glucanases
57180 - Cellulose-binding domain | 0 | DIRECT |
55846,47090
55846 - N-acetylmuramoyl-L-alanine amidase-like
47090 - PGBD-like | 0 | DIRECT |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | DIRECT |
56601,52091
56601 - beta-lactamase/transpeptidase-like
52091 - SpoIIaa-like | 0 | DIRECT |
54637,55961
54637 - Thioesterase/thiol ester dehydrase-isomerase
55961 - Bet v1-like | 0 | DIRECT |
49899,110221
49899 - Concanavalin A-like lectins/glucanases
110221 - AbfB domain | 0 | DIRECT |
51445,49785
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like | 0 | DIRECT |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
56601,69189
56601 - beta-lactamase/transpeptidase-like
69189 - Penicillin-binding protein associated domain | 0 | DIRECT |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
49303,74650
49303 - beta-Galactosidase/glucuronidase domain
74650 - Galactose mutarotase-like | 0 | DIRECT |
51445,51055
51445 - (Trans)glycosidases
51055 - Carbohydrate binding domain | 0 | DIRECT |
52540,52156
52540 - P-loop containing nucleoside triphosphate hydrolases
52156 - Initiation factor IF2/eIF5b, domain 3 | 0 | DIRECT |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | DIRECT |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
64571,64571
64571 - Cellulose docking domain, dockering
64571 - Cellulose docking domain, dockering | 0 | DIRECT |
54106,54001
54106 - LysM domain
54001 - Cysteine proteinases | 0 | DIRECT |
55608,56712
55608 - Homing endonucleases
56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
51126,51126
51126 - Pectin lyase-like
51126 - Pectin lyase-like | 0 | DIRECT |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
51445,140657
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
52540,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
56219,56219
56219 - DNase I-like
56219 - DNase I-like | 0 | DIRECT |
100895,56487
100895 - Kazal-type serine protease inhibitors
56487 - SRCR-like | 0 | DIRECT |
55811,55811
55811 - Nudix
55811 - Nudix | 0 | DIRECT |
49854,49854
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
140657,49785
140657 - Hyaluronidase post-catalytic domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | DIRECT |
81761,53474
81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
49384,49265
49384 - Carbohydrate-binding domain
49265 - Fibronectin type III | 0 | DIRECT |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | DIRECT |
54001,46934
54001 - Cysteine proteinases
46934 - UBA-like | 0 | DIRECT |
52279,56988
52279 - Beta-D-glucan exohydrolase, C-terminal domain
56988 - Anthrax protective antigen | 0 | DIRECT |
49899,49785
49899 - Concanavalin A-like lectins/glucanases
49785 - Galactose-binding domain-like | 0 | DIRECT |
56519,56601
56519 - Penicillin binding protein dimerisation domain
56601 - beta-lactamase/transpeptidase-like | 0 | DIRECT |
101821,53187
101821 - Aminopeptidase/glucanase lid domain
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
53092,55920
53092 - Creatinase/prolidase N-terminal domain
55920 - Creatinase/aminopeptidase | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
100939,68906
100939 - SPOC domain-like
68906 - SAP domain | 0 | DIRECT |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
101908,56219
101908 - Putative isomerase YbhE
56219 - DNase I-like | 0 | DIRECT |
56784,52540
56784 - HAD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54001,49785
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | DIRECT |
53092,53092
53092 - Creatinase/prolidase N-terminal domain
53092 - Creatinase/prolidase N-terminal domain | 0 | DIRECT |
52151,51412
52151 - FabD/lysophospholipase-like
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | DIRECT |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | DIRECT |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 0 | DIRECT |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | DIRECT |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
75005,49899
75005 - Arabinanase/levansucrase/invertase
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49384,57615
49384 - Carbohydrate-binding domain
57615 - Type X cellulose binding domain, CBDX | 0 | DIRECT |
54403,54001
54403 - Cystatin/monellin
54001 - Cysteine proteinases | 0 | DIRECT |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0 | DIRECT |
49562,54236
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
54236 - Ubiquitin-like | 0 | DIRECT |
47819,47819
47819 - HRDC-like
47819 - HRDC-like | 0 | DIRECT |
57603,57440
57603 - FnI-like domain
57440 - Kringle-like | 0 | DIRECT |
50156,52096
50156 - PDZ domain-like
52096 - ClpP/crotonase | 0 | DIRECT |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
140586,55811
140586 - Dcp2 domain-like
55811 - Nudix | 0 | DIRECT |
49265,49384
49265 - Fibronectin type III
49384 - Carbohydrate-binding domain | 0 | DIRECT |
51445,52279
51445 - (Trans)glycosidases
52279 - Beta-D-glucan exohydrolase, C-terminal domain | 0 | DIRECT |
52087,52799
52087 - CRAL/TRIO domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
53098,53098
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | DIRECT |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
-8,52540
-8 - ECOD
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,50494
53300 - vWA-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
50974,50974
50974 - Nitrous oxide reductase, N-terminal domain
50974 - Nitrous oxide reductase, N-terminal domain | 0 | DIRECT |
52799,56091
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
49899,50386
49899 - Concanavalin A-like lectins/glucanases
50386 - STI-like | 0 | DIRECT |
89260,89260
89260 - Collagen-binding domain
89260 - Collagen-binding domain | 0 | DIRECT |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
75001,54001
75001 - Dipeptidyl peptidase I (cathepsin C), exclusion domain
54001 - Cysteine proteinases | 0 | DIRECT |
54111,51278
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit | 0 | DIRECT |
47836,47943
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain | 0 | DIRECT |
49384,51445
49384 - Carbohydrate-binding domain
51445 - (Trans)glycosidases | 0 | DIRECT |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57180,51445
57180 - Cellulose-binding domain
51445 - (Trans)glycosidases | 0 | DIRECT |
52949,53187
52949 - Macro domain-like
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
51445,81296
51445 - (Trans)glycosidases
81296 - E set domains | 0 | DIRECT |
51011,117100
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3 | 0 | DIRECT |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | DIRECT |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
56568,47233
56568 - Non-globular alpha+beta subunits of globular proteins
47233 - Bacterial GAP domain | 0 | DIRECT |
48452,56300
48452 - TPR-like
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
51695,51695
51695 - PLC-like phosphodiesterases
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
51445,52317
51445 - (Trans)glycosidases
52317 - Class I glutamine amidotransferase-like | 0 | DIRECT |
58091,49899
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0 | DIRECT |
101386,101386
101386 - all-alpha NTP pyrophosphatases
101386 - all-alpha NTP pyrophosphatases | 0 | DIRECT |
57424,49854
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49854,50494
49854 - Spermadhesin, CUB domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
49899,48726
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin | 0 | DIRECT |
52129,81296
52129 - Caspase-like
81296 - E set domains | 0 | DIRECT |
50249,56300
50249 - Nucleic acid-binding proteins
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
54980,54980
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
50886,50886
50886 - D-aminopeptidase, middle and C-terminal domains
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
101386,53720
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | DIRECT |
56672,46919
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
103642,55920
103642 - Sec-C motif
55920 - Creatinase/aminopeptidase | 0 | DIRECT |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
81324,52799
81324 - Voltage-gated potassium channels
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
49758,47473
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | DIRECT |
56601,50886
56601 - beta-lactamase/transpeptidase-like
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
55658,53098
55658 - L9 N-domain-like
53098 - Ribonuclease H-like | 0 | DIRECT |
52499,47336
52499 - Isochorismatase-like hydrolases
47336 - ACP-like | 0 | DIRECT |
57756,51283
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0 | DIRECT |
51069,49265
51069 - Carbonic anhydrase
49265 - Fibronectin type III | 0 | DIRECT |
49303,51445
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases | 0 | DIRECT |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
100939,101420
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | DIRECT |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
69065,69065
69065 - RNase III domain-like
69065 - RNase III domain-like | 0 | DIRECT |
53474,49723
53474 - alpha/beta-Hydrolases
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | DIRECT |
82671,49854
82671 - SEA domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
53098,47819
53098 - Ribonuclease H-like
47819 - HRDC-like | 0 | DIRECT |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
-9,52540
-9 - PDB
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
51278,51338
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
48150,55811
48150 - DNA-glycosylase
55811 - Nudix | 0 | DIRECT |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | DIRECT |
55021,53328
55021 - ACT-like
53328 - Formyltransferase | 0 | DIRECT |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
46785,51306
46785 - "Winged helix" DNA-binding domain
51306 - LexA/Signal peptidase | 0 | DIRECT |
81624,46946
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain | 0 | DIRECT |
110296,110296
110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase
110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | DIRECT |
51445,49303
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | DIRECT |
57184,50494
57184 - Growth factor receptor domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
55486,57440
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like | 0 | DIRECT |
52540,-9
52540 - P-loop containing nucleoside triphosphate hydrolases
-9 - PDB | 0 | DIRECT |
52156,50447
52156 - Initiation factor IF2/eIF5b, domain 3
50447 - Translation proteins | 0 | DIRECT |
49303,49303
49303 - beta-Galactosidase/glucuronidase domain
49303 - beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0 | DIRECT |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | DIRECT |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
49299,89260
49299 - PKD domain
89260 - Collagen-binding domain | 0 | DIRECT |
57535,53300
57535 - Complement control module/SCR domain
53300 - vWA-like | 0 | DIRECT |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | DIRECT |
56371,50370
56371 - Ribosome inactivating proteins (RIP)
50370 - Ricin B-like lectins | 0 | DIRECT |
49899,49854
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49363,56300
49363 - Purple acid phosphatase, N-terminal domain
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
50044,51695
50044 - SH3-domain
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
54001,143791
54001 - Cysteine proteinases
143791 - DUSP-like | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
54001,55205
54001 - Cysteine proteinases
55205 - EPT/RTPC-like | 0 | DIRECT |
56487,57424
56487 - SRCR-like
57424 - LDL receptor-like module | 0 | DIRECT |
49344,49344
49344 - CBD9-like
49344 - CBD9-like | 0 | DIRECT |
57440,57196
57440 - Kringle-like
57196 - EGF/Laminin | 0 | DIRECT |
50199,63748
50199 - Staphylococcal nuclease
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
52317,141986
52317 - Class I glutamine amidotransferase-like
141986 - LD-carboxypeptidase A C-terminal domain-like | 0 | DIRECT |
52335,53927
52335 - Methylglyoxal synthase-like
53927 - Cytidine deaminase-like | 0 | DIRECT |
54637,52151
54637 - Thioesterase/thiol ester dehydrase-isomerase
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
49562,52151
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
52266,49818
52266 - SGNH hydrolase
49818 - Viral protein domain | 0 | DIRECT |
49785,63446
49785 - Galactose-binding domain-like
63446 - Type I dockerin domain | 0 | DIRECT |
82708,53098
82708 - R3H domain
53098 - Ribonuclease H-like | 0 | DIRECT |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
51011,51445
51011 - Glycosyl hydrolase domain
51445 - (Trans)glycosidases | 0 | DIRECT |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
49785,51445
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases | 0 | DIRECT |
52200,52540
52200 - Toll/Interleukin receptor TIR domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47769,52200
47769 - SAM/Pointed domain
52200 - Toll/Interleukin receptor TIR domain | 0 | DIRECT |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0 | DIRECT |
49899,49599
49899 - Concanavalin A-like lectins/glucanases
49599 - TRAF domain-like | 0 | DIRECT |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
56300,47473
56300 - Metallo-dependent phosphatases
47473 - EF-hand | 0 | DIRECT |
51011,50370
51011 - Glycosyl hydrolase domain
50370 - Ricin B-like lectins | 0 | DIRECT |
48208,63446
48208 - Six-hairpin glycosidases
63446 - Type I dockerin domain | 0 | DIRECT |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | DIRECT |
49265,49452
49265 - Fibronectin type III
49452 - Starch-binding domain-like | 0 | DIRECT |
143791,54236
143791 - DUSP-like
54236 - Ubiquitin-like | 0 | DIRECT |
57630,57440
57630 - GLA-domain
57440 - Kringle-like | 0 | DIRECT |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
53474,49785
53474 - alpha/beta-Hydrolases
49785 - Galactose-binding domain-like | 0 | DIRECT |
52151,52151
52151 - FabD/lysophospholipase-like
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
51445,64571
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering | 0 | DIRECT |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | DIRECT |
53756,53067
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53067 - Actin-like ATPase domain | 0 | DIRECT |
51445,49384
51445 - (Trans)glycosidases
49384 - Carbohydrate-binding domain | 0 | DIRECT |
55486,58091
55486 - Metalloproteases ("zincins"), catalytic domain
58091 - Clostridium neurotoxins, "coiled-coil" domain | 0 | DIRECT |
52266,103515
52266 - SGNH hydrolase
103515 - Autotransporter | 0 | DIRECT |
55781,109604
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | DIRECT |
57016,53955
57016 - Plant lectins/antimicrobial peptides
53955 - Lysozyme-like | 0 | DIRECT |
47090,47090
47090 - PGBD-like
47090 - PGBD-like | 0 | DIRECT |
48371,47769
48371 - ARM repeat
47769 - SAM/Pointed domain | 0 | DIRECT |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | DIRECT |
52540,-8
52540 - P-loop containing nucleoside triphosphate hydrolases
-8 - ECOD | 0 | DIRECT |
55154,56091
55154 - CYTH-like phosphatases
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | DIRECT |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | DIRECT |
54211,54637
54211 - Ribosomal protein S5 domain 2-like
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | DIRECT |
52058,56219
52058 - L domain-like
56219 - DNase I-like | 0 | DIRECT |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0 | DIRECT |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | DIRECT |
49562,56024
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56024 - Phospholipase D/nuclease | 0 | DIRECT |
46785,47819
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | DIRECT |
54211,54211
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
48208,49384
48208 - Six-hairpin glycosidases
49384 - Carbohydrate-binding domain | 0 | DIRECT |
52540,57756
52540 - P-loop containing nucleoside triphosphate hydrolases
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
74924,54001
74924 - Cap-Gly domain
54001 - Cysteine proteinases | 0 | DIRECT |
47233,52799
47233 - Bacterial GAP domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
49899,49384
49899 - Concanavalin A-like lectins/glucanases
49384 - Carbohydrate-binding domain | 0 | DIRECT |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
49854,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | DIRECT |
50494,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | DIRECT |
141734,101386
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases | 0 | DIRECT |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
50370,50370
50370 - Ricin B-like lectins
50370 - Ricin B-like lectins | 0 | DIRECT |
159672,159664
159672 - CbiG N-terminal domain-like
159664 - CobE/GbiG C-terminal domain-like | 0 | DIRECT |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
56487,50494
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
50156,52799
50156 - PDZ domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
53649,54060
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0 | DIRECT |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
55486,49899
55486 - Metalloproteases ("zincins"), catalytic domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
56784,53474
56784 - HAD-like
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | DIRECT |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | DIRECT |
51445,49344
51445 - (Trans)glycosidases
49344 - CBD9-like | 0 | DIRECT |
56784,56784
56784 - HAD-like
56784 - HAD-like | 0 | DIRECT |
52172,52738
52172 - CheY-like
52738 - Methylesterase CheB, C-terminal domain | 0 | DIRECT |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | DIRECT |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
53067,109604
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | DIRECT |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | DIRECT |
55550,52799
55550 - SH2 domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
53474,53474
53474 - alpha/beta-Hydrolases
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
52540,54211
52540 - P-loop containing nucleoside triphosphate hydrolases
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
57424,50494
57424 - LDL receptor-like module
50494 - Trypsin-like serine proteases | 0 | DIRECT |
57630,57184
57630 - GLA-domain
57184 - Growth factor receptor domain | 0 | DIRECT |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
56300,56300
56300 - Metallo-dependent phosphatases
56300 - Metallo-dependent phosphatases | 0 | DIRECT |
50729,56024
50729 - PH domain-like
56024 - Phospholipase D/nuclease | 0 | DIRECT |
116846,52540
116846 - MIT domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50916,46785
50916 - Rap30/74 interaction domains
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
101148,51126
101148 - Plant invertase/pectin methylesterase inhibitor
51126 - Pectin lyase-like | 0 | DIRECT |
47781,46929
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
160481,160481
160481 - BRK domain-like
160481 - BRK domain-like | 0 | DIRECT |
49879,54197
49879 - SMAD/FHA domain
54197 - HIT-like | 0 | DIRECT |
56219,54928
56219 - DNase I-like
54928 - RNA-binding domain, RBD | 0 | DIRECT |
81296,48208
81296 - E set domains
48208 - Six-hairpin glycosidases | 0 | DIRECT |
57424,56487
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | DIRECT |
50249,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
52540,49899
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
158702,81296
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | DIRECT |
56300,55816
56300 - Metallo-dependent phosphatases
55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | DIRECT |
56731,52540
56731 - DNA primase core
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55545,51445
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases | 0 | DIRECT |
46946,57716
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
57492,74650
57492 - Trefoil
74650 - Galactose mutarotase-like | 0 | DIRECT |
53774,48403
53774 - Glutaminase/Asparaginase
48403 - Ankyrin repeat | 0 | DIRECT |
56784,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
49452,52799
49452 - Starch-binding domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | DIRECT |
48371,54001
48371 - ARM repeat
54001 - Cysteine proteinases | 0 | DIRECT |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | DIRECT |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
50199,50199
50199 - Staphylococcal nuclease
50199 - Staphylococcal nuclease | 0 | DIRECT |
54001,53098
54001 - Cysteine proteinases
53098 - Ribonuclease H-like | 0 | DIRECT |
54236,54001
54236 - Ubiquitin-like
54001 - Cysteine proteinases | 0 | DIRECT |
49854,49899
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
54001,144232
54001 - Cysteine proteinases
144232 - HIT/MYND zinc finger-like | 0 | DIRECT |
143503,54001
143503 - PUG domain-like
54001 - Cysteine proteinases | 0 | DIRECT |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | DIRECT |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
158702,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
117100,49785
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like | 0 | DIRECT |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51445,57180
51445 - (Trans)glycosidases
57180 - Cellulose-binding domain | 0 | DIRECT |
51283,51283
51283 - dUTPase-like
51283 - dUTPase-like | 0 | DIRECT |
50993,53474
50993 - Peptidase/esterase 'gauge' domain
53474 - alpha/beta-Hydrolases | 0 | DIRECT |
51011,49265
51011 - Glycosyl hydrolase domain
49265 - Fibronectin type III | 0 | DIRECT |
49464,53187
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | DIRECT |
51283,50630
51283 - dUTPase-like
50630 - Acid proteases | 0 | DIRECT |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | DIRECT |
48537,49723
48537 - Phospholipase C/P1 nuclease
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | DIRECT |
50249,47781
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like | 0 | DIRECT |
109715,52799
109715 - DEK C-terminal domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
55464,52540
55464 - Origin of replication-binding domain, RBD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53955,54106
53955 - Lysozyme-like
54106 - LysM domain | 0 | DIRECT |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | DIRECT |
53300,100939
53300 - vWA-like
100939 - SPOC domain-like | 0 | DIRECT |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | DIRECT |
48208,49452
48208 - Six-hairpin glycosidases
49452 - Starch-binding domain-like | 0 | DIRECT |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
74924,74924
74924 - Cap-Gly domain
74924 - Cap-Gly domain | 0 | DIRECT |
54236,56784
54236 - Ubiquitin-like
56784 - HAD-like | 0 | DIRECT |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | DIRECT |
52540,48403
52540 - P-loop containing nucleoside triphosphate hydrolases
48403 - Ankyrin repeat | 0 | DIRECT |
143791,143791
143791 - DUSP-like
143791 - DUSP-like | 0 | DIRECT |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
52768,52768
52768 - Arginase/deacetylase
52768 - Arginase/deacetylase | 0 | DIRECT |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | DIRECT |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | DIRECT |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | DIRECT |
48024,52540
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49785,49303
49785 - Galactose-binding domain-like
49303 - beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | DIRECT |
52540,54928
52540 - P-loop containing nucleoside triphosphate hydrolases
54928 - RNA-binding domain, RBD | 0 | DIRECT |
52540,55144
52540 - P-loop containing nucleoside triphosphate hydrolases
55144 - LigT-like | 0 | DIRECT |
55821,142695
55821 - YrdC/RibB
142695 - RibA-like | 0 | DIRECT |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | DIRECT |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
52317,51011
52317 - Class I glutamine amidotransferase-like
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
49384,55545
49384 - Carbohydrate-binding domain
55545 - beta-N-acetylhexosaminidase-like domain | 0 | DIRECT |
63433,56529
63433 - Fumarylacetoacetate hydrolase, FAH, N-terminal domain
56529 - FAH | 0 | DIRECT |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 3.548e-16 | DIRECT |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 5.316e-16 | DIRECT |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.00000000000006338 | DIRECT |
54106,54106
54106 - LysM domain
54106 - LysM domain | 0.000000000001862 | DIRECT |
88688,74650
88688 - Families 57/38 glycoside transferase middle domain
74650 - Galactose mutarotase-like | 0.00000000002664 | DIRECT |
51735,52283
51735 - NAD(P)-binding Rossmann-fold domains
52283 - Formate/glycerate dehydrogenase catalytic domain-like | 0.0000000000457 | DIRECT |
53955,56601
53955 - Lysozyme-like
56601 - beta-lactamase/transpeptidase-like | 0.0000000000457 | DIRECT |
53927,53597
53927 - Cytidine deaminase-like
53597 - Dihydrofolate reductase-like | 0.0000000001248 | DIRECT |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.00000001244 | DIRECT |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.00000001315 | DIRECT |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0.00000002724 | DIRECT |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.00000007459 | DIRECT |
64268,50729
64268 - PX domain
50729 - PH domain-like | 0.0000006634 | DIRECT |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0.000002298 | DIRECT |
51011,49452
51011 - Glycosyl hydrolase domain
49452 - Starch-binding domain-like | 0.00001607 | DIRECT |
55073,141868
55073 - Nucleotide cyclase
141868 - EAL domain-like | 0.00001607 | DIRECT |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00002349 | DIRECT |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00002356 | DIRECT |
52540,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0.00002757 | DIRECT |
160467,50891
160467 - PH0987 N-terminal domain-like
50891 - Cyclophilin-like | 0.00007897 | DIRECT |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.00008918 | DIRECT |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.00009526 | DIRECT |
63748,50199
63748 - Tudor/PWWP/MBT
50199 - Staphylococcal nuclease | 0.0001035 | DIRECT |
49899,50939
49899 - Concanavalin A-like lectins/glucanases
50939 - Sialidases | 0.0003875 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.0004372 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0.001462 | INHERITED FROM: In cyclic amidines || Double-stranded RNA adenine deaminase |
49785,81296
49785 - Galactose-binding domain-like
81296 - E set domains | 0.0019 | INHERITED FROM: Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds || Glycosylases |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0.001905 | INHERITED FROM: Acting on peptide bonds (peptidases) || Omega peptidases || Ubiquitinyl hydrolase 1 |
56712,51294
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0.001905 | INHERITED FROM: Acting on acid anhydrides || Acting on ATP; involved in cellular and subcellular movement || DNA helicase |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.002807 | INHERITED FROM: In cyclic amides || Dihydroorotase || Acting on carbon-nitrogen bonds, other than peptide bonds |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.005052 | INHERITED FROM: Acting on ester bonds || Protein-tyrosine-phosphatase || Phosphoric monoester hydrolases |
47336,53474
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.007395 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Acting on ester bonds || Thiolester hydrolases |
51294,55608
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0.01145 | INHERITED FROM: Acting on acid anhydrides || Acting on ATP; involved in cellular and subcellular movement || DNA helicase |
53474,53335
53474 - alpha/beta-Hydrolases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.01954 | INHERITED FROM: Acting on ester bonds || Carboxylic ester hydrolases || Carboxylesterase |
81296,51445
81296 - E set domains
51445 - (Trans)glycosidases | 0.02869 | INHERITED FROM: Limit dextrin alpha-1,6-maltotetraose-hydrolase || Isoamylase || 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase || Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds || Glycosylases || Pullulanase || Neopullulanase |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0.02897 | INHERITED FROM: Acting on ester bonds || Thiolester hydrolases || Acetyl-CoA hydrolase |
81301,81271
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.05535 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Acting on ester bonds || Diphosphoric monoester hydrolases |
55608,52540
55608 - Homing endonucleases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.06378 | INHERITED FROM: Acting on acid anhydrides || Acting on ATP; involved in cellular and subcellular movement || DNA helicase |
55945,48150
55945 - TATA-box binding protein-like
48150 - DNA-glycosylase | 0.09636 | INHERITED FROM: Hydrolyzing N-glycosyl compounds || Glycosylases || DNA-3-methyladenine glycosylase II |
109604,81301
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase | 0.1308 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Acting on ester bonds || Diphosphoric monoester hydrolases |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0.1352 | INHERITED FROM: Phosphoric diester hydrolases || Phosphoinositide phospholipase C |
74650,48208
74650 - Galactose mutarotase-like
48208 - Six-hairpin glycosidases | 0.2529 | INHERITED FROM: Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds || Alpha,alpha-trehalase || Glycosylases |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.277 | INHERITED FROM: Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds || Glycosylases |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0.2921 | INHERITED FROM: Trehalose-phosphatase || Phosphoric monoester hydrolases |
52317,51366
52317 - Class I glutamine amidotransferase-like
51366 - Ribulose-phoshate binding barrel | 0.3097 | INHERITED FROM: In linear amides || Glutaminase |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0.3566 | INHERITED FROM: Phosphoric diester hydrolases || Acting on ester bonds || Exonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters || Phospholipase D |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0.3982 | INHERITED FROM: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase || Hydrolyzing N-glycosyl compounds || Protein-serine/threonine phosphatase || Phosphoric monoester hydrolases |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0.5818 | INHERITED FROM: In phosphorus-containing anhydrides || Adenosinetriphosphatase |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0.6528 | INHERITED FROM: Serine endopeptidases || Furin || Acting on peptide bonds (peptidases) |
51735,51735
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.7921 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Thiolester hydrolases |
51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.807 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Thiolester hydrolases |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 1 | INHERITED FROM: In cyclic amides || Dihydroorotase |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 1 | INHERITED FROM: Polynucleotide 5'-phosphatase |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 1 | INHERITED FROM: Ribonuclease H || Endoribonucleases producing 5'-phosphomonoesters |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 1 | INHERITED FROM: Acting on acid anhydrides; catalyzing transmembrane movement of substances |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 1 | INHERITED FROM: Acting on acid anhydrides || Guanosine-5'-triphosphate,3'-diphosphate diphosphatase || In phosphorus-containing anhydrides || Exopolyphosphatase || Non-chaperonin molecular chaperone ATPase |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | INHERITED FROM: In cyclic amides || Dihydroorotase |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | INHERITED FROM: In cyclic amides || Dihydroorotase |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 1 | INHERITED FROM: Maltose-6'-phosphate glucosidase || Alpha-galactosidase || 6-phospho-beta-glucosidase || Alpha-glucosidase || Galacturonan 1,4-alpha-galacturonidase |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: Dihydroorotase |
52151,55048
52151 - FabD/lysophospholipase-like
55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Thiolester hydrolases |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 1 | INHERITED FROM: Palmitoyl-CoA hydrolase || Acetyl-CoA hydrolase |
52518,52467
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain | 1 | INHERITED FROM: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) || Acting on carbon-carbon bonds |
48239,48576
48239 - Terpenoid cyclases/Protein prenyltransferases
48576 - Terpenoid synthases | 1 | INHERITED FROM: Geranyl diphosphate diphosphatase || Diphosphoric monoester hydrolases |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | INHERITED FROM: Protein-tyrosine-phosphatase || Phosphoric monoester hydrolases |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: In cyclic amides || Dihydroorotase |
52467,52518
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 1 | INHERITED FROM: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) || Acting on carbon-carbon bonds |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
101596,51126
101596 - Dextranase, N-terminal domain
51126 - Pectin lyase-like | 0 | Direct |
57850,54001
57850 - RING/U-box
54001 - Cysteine proteinases | 0 | Direct |
102860,54197
102860 - mRNA decapping enzyme DcpS N-terminal domain
54197 - HIT-like | 0 | Direct |
82671,57424
82671 - SEA domain
57424 - LDL receptor-like module | 0 | Direct |
56784,54427
56784 - HAD-like
54427 - NTF2-like | 0 | Direct |
51556,51338
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
90188,90188
90188 - Somatomedin B domain
90188 - Somatomedin B domain | 0 | Direct |
53639,56784
53639 - AraD/HMP-PK domain-like
56784 - HAD-like | 0 | Direct |
50494,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49265,51445
49265 - Fibronectin type III
51445 - (Trans)glycosidases | 0 | Direct |
55486,51120
55486 - Metalloproteases ("zincins"), catalytic domain
51120 - beta-Roll | 0 | Direct |
51445,63446
51445 - (Trans)glycosidases
63446 - Type I dockerin domain | 0 | Direct |
49599,54001
49599 - TRAF domain-like
54001 - Cysteine proteinases | 0 | Direct |
53098,54928
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | Direct |
52743,52025
52743 - Subtilisin-like
52025 - PA domain | 0 | Direct |
49899,57180
49899 - Concanavalin A-like lectins/glucanases
57180 - Cellulose-binding domain | 0 | Direct |
55846,47090
55846 - N-acetylmuramoyl-L-alanine amidase-like
47090 - PGBD-like | 0 | Direct |
54897,52743
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like | 0 | Direct |
56601,52091
56601 - beta-lactamase/transpeptidase-like
52091 - SpoIIaa-like | 0 | Direct |
54637,55961
54637 - Thioesterase/thiol ester dehydrase-isomerase
55961 - Bet v1-like | 0 | Direct |
49899,110221
49899 - Concanavalin A-like lectins/glucanases
110221 - AbfB domain | 0 | Direct |
51445,49785
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like | 0 | Direct |
69065,54768
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
56601,69189
56601 - beta-lactamase/transpeptidase-like
69189 - Penicillin-binding protein associated domain | 0 | Direct |
52821,52799
52821 - Rhodanese/Cell cycle control phosphatase
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
49303,74650
49303 - beta-Galactosidase/glucuronidase domain
74650 - Galactose mutarotase-like | 0 | Direct |
51445,51055
51445 - (Trans)glycosidases
51055 - Carbohydrate binding domain | 0 | Direct |
52540,52156
52540 - P-loop containing nucleoside triphosphate hydrolases
52156 - Initiation factor IF2/eIF5b, domain 3 | 0 | Direct |
89043,50494
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | Direct |
53098,50122
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
64571,64571
64571 - Cellulose docking domain, dockering
64571 - Cellulose docking domain, dockering | 0 | Direct |
54106,54001
54106 - LysM domain
54001 - Cysteine proteinases | 0 | Direct |
55608,56712
55608 - Homing endonucleases
56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
51126,51126
51126 - Pectin lyase-like
51126 - Pectin lyase-like | 0 | Direct |
90188,53649
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
51445,140657
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
52540,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like | 0 | Direct |
56219,56219
56219 - DNase I-like
56219 - DNase I-like | 0 | Direct |
100895,56487
100895 - Kazal-type serine protease inhibitors
56487 - SRCR-like | 0 | Direct |
55811,55811
55811 - Nudix
55811 - Nudix | 0 | Direct |
49854,49854
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
140657,49785
140657 - Hyaluronidase post-catalytic domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
52980,47781
52980 - Restriction endonuclease-like
47781 - RuvA domain 2-like | 0 | Direct |
81761,53474
81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
53474 - alpha/beta-Hydrolases | 0 | Direct |
53187,47672
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
49384,49265
49384 - Carbohydrate-binding domain
49265 - Fibronectin type III | 0 | Direct |
50249,50249
50249 - Nucleic acid-binding proteins
50249 - Nucleic acid-binding proteins | 0 | Direct |
52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | Direct |
54001,46934
54001 - Cysteine proteinases
46934 - UBA-like | 0 | Direct |
52279,56988
52279 - Beta-D-glucan exohydrolase, C-terminal domain
56988 - Anthrax protective antigen | 0 | Direct |
49899,49785
49899 - Concanavalin A-like lectins/glucanases
49785 - Galactose-binding domain-like | 0 | Direct |
56519,56601
56519 - Penicillin binding protein dimerisation domain
56601 - beta-lactamase/transpeptidase-like | 0 | Direct |
101821,53187
101821 - Aminopeptidase/glucanase lid domain
53187 - Zn-dependent exopeptidases | 0 | Direct |
53092,55920
53092 - Creatinase/prolidase N-terminal domain
55920 - Creatinase/aminopeptidase | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
100939,68906
100939 - SPOC domain-like
68906 - SAP domain | 0 | Direct |
49899,52540
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
101908,56219
101908 - Putative isomerase YbhE
56219 - DNase I-like | 0 | Direct |
56784,52540
56784 - HAD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54001,49785
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | Direct |
53092,53092
53092 - Creatinase/prolidase N-terminal domain
53092 - Creatinase/prolidase N-terminal domain | 0 | Direct |
52151,51412
52151 - FabD/lysophospholipase-like
51412 - Inosine monophosphate dehydrogenase (IMPDH) | 0 | Direct |
54001,49758
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III) | 0 | Direct |
55781,55781
55781 - GAF domain-like
55781 - GAF domain-like | 0 | Direct |
82171,53474
82171 - DPP6 N-terminal domain-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
88713,88688
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain | 0 | Direct |
57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
75005,49899
75005 - Arabinanase/levansucrase/invertase
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49384,57615
49384 - Carbohydrate-binding domain
57615 - Type X cellulose binding domain, CBDX | 0 | Direct |
54403,54001
54403 - Cystatin/monellin
54001 - Cysteine proteinases | 0 | Direct |
56983,81296
56983 - Viral glycoprotein, central and dimerisation domains
81296 - E set domains | 0 | Direct |
49562,54236
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
54236 - Ubiquitin-like | 0 | Direct |
47819,47819
47819 - HRDC-like
47819 - HRDC-like | 0 | Direct |
57603,57440
57603 - FnI-like domain
57440 - Kringle-like | 0 | Direct |
50156,52096
50156 - PDZ domain-like
52096 - ClpP/crotonase | 0 | Direct |
50494,56672
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | Direct |
140586,55811
140586 - Dcp2 domain-like
55811 - Nudix | 0 | Direct |
49265,49384
49265 - Fibronectin type III
49384 - Carbohydrate-binding domain | 0 | Direct |
51445,52279
51445 - (Trans)glycosidases
52279 - Beta-D-glucan exohydrolase, C-terminal domain | 0 | Direct |
52087,52799
52087 - CRAL/TRIO domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
53098,53098
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | Direct |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
-8,52540
-8 - ECOD
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,50494
53300 - vWA-like
50494 - Trypsin-like serine proteases | 0 | Direct |
50974,50974
50974 - Nitrous oxide reductase, N-terminal domain
50974 - Nitrous oxide reductase, N-terminal domain | 0 | Direct |
52799,56091
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
49899,50386
49899 - Concanavalin A-like lectins/glucanases
50386 - STI-like | 0 | Direct |
89260,89260
89260 - Collagen-binding domain
89260 - Collagen-binding domain | 0 | Direct |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
56672,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
75001,54001
75001 - Dipeptidyl peptidase I (cathepsin C), exclusion domain
54001 - Cysteine proteinases | 0 | Direct |
54111,51278
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit | 0 | Direct |
47836,47943
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain | 0 | Direct |
49384,51445
49384 - Carbohydrate-binding domain
51445 - (Trans)glycosidases | 0 | Direct |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57180,51445
57180 - Cellulose-binding domain
51445 - (Trans)glycosidases | 0 | Direct |
52949,53187
52949 - Macro domain-like
53187 - Zn-dependent exopeptidases | 0 | Direct |
51445,81296
51445 - (Trans)glycosidases
81296 - E set domains | 0 | Direct |
51011,117100
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3 | 0 | Direct |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0 | Direct |
47353,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
56568,47233
56568 - Non-globular alpha+beta subunits of globular proteins
47233 - Bacterial GAP domain | 0 | Direct |
48452,56300
48452 - TPR-like
56300 - Metallo-dependent phosphatases | 0 | Direct |
51695,51695
51695 - PLC-like phosphodiesterases
51695 - PLC-like phosphodiesterases | 0 | Direct |
51445,52317
51445 - (Trans)glycosidases
52317 - Class I glutamine amidotransferase-like | 0 | Direct |
58091,49899
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
51338,51556
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
140367,143076
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like | 0 | Direct |
101386,101386
101386 - all-alpha NTP pyrophosphatases
101386 - all-alpha NTP pyrophosphatases | 0 | Direct |
57424,49854
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain | 0 | Direct |
49854,50494
49854 - Spermadhesin, CUB domain
50494 - Trypsin-like serine proteases | 0 | Direct |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
49899,48726
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin | 0 | Direct |
52129,81296
52129 - Caspase-like
81296 - E set domains | 0 | Direct |
50249,56300
50249 - Nucleic acid-binding proteins
56300 - Metallo-dependent phosphatases | 0 | Direct |
54980,54980
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
50886,50886
50886 - D-aminopeptidase, middle and C-terminal domains
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
53187,49464
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
101386,53720
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | Direct |
56672,46919
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
103642,55920
103642 - Sec-C motif
55920 - Creatinase/aminopeptidase | 0 | Direct |
55486,48371
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
81324,52799
81324 - Voltage-gated potassium channels
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
49758,47473
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | Direct |
56601,50886
56601 - beta-lactamase/transpeptidase-like
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
55658,53098
55658 - L9 N-domain-like
53098 - Ribonuclease H-like | 0 | Direct |
52499,47336
52499 - Isochorismatase-like hydrolases
47336 - ACP-like | 0 | Direct |
57756,51283
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0 | Direct |
51069,49265
51069 - Carbonic anhydrase
49265 - Fibronectin type III | 0 | Direct |
49303,51445
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases | 0 | Direct |
49854,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
100939,101420
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | Direct |
63737,55486
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
69065,69065
69065 - RNase III domain-like
69065 - RNase III domain-like | 0 | Direct |
53474,49723
53474 - alpha/beta-Hydrolases
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | Direct |
82671,49854
82671 - SEA domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
53098,47819
53098 - Ribonuclease H-like
47819 - HRDC-like | 0 | Direct |
52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
-9,52540
-9 - PDB
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46919,53098
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
51278,51338
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
48150,55811
48150 - DNA-glycosylase
55811 - Nudix | 0 | Direct |
52743,49785
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
57414,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like | 0 | Direct |
55021,53328
55021 - ACT-like
53328 - Formyltransferase | 0 | Direct |
51445,51011
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
46785,51306
46785 - "Winged helix" DNA-binding domain
51306 - LexA/Signal peptidase | 0 | Direct |
81624,46946
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain | 0 | Direct |
110296,110296
110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase
110296 - Oligoxyloglucan reducing end-specific cellobiohydrolase | 0 | Direct |
51445,49303
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain | 0 | Direct |
52540,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins | 0 | Direct |
57184,50494
57184 - Growth factor receptor domain
50494 - Trypsin-like serine proteases | 0 | Direct |
55486,57440
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like | 0 | Direct |
52540,-9
52540 - P-loop containing nucleoside triphosphate hydrolases
-9 - PDB | 0 | Direct |
52156,50447
52156 - Initiation factor IF2/eIF5b, domain 3
50447 - Translation proteins | 0 | Direct |
49303,49303
49303 - beta-Galactosidase/glucuronidase domain
49303 - beta-Galactosidase/glucuronidase domain | 0 | Direct |
159936,52949
159936 - NSP3A-like
52949 - Macro domain-like | 0 | Direct |
53098,51283
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | Direct |
53098,46919
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
54897,53187
54897 - Protease propeptides/inhibitors
53187 - Zn-dependent exopeptidases | 0 | Direct |
49299,89260
49299 - PKD domain
89260 - Collagen-binding domain | 0 | Direct |
57535,53300
57535 - Complement control module/SCR domain
53300 - vWA-like | 0 | Direct |
52283,51735
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
53335,56672
53335 - S-adenosyl-L-methionine-dependent methyltransferases
56672 - DNA/RNA polymerases | 0 | Direct |
56371,50370
56371 - Ribosome inactivating proteins (RIP)
50370 - Ricin B-like lectins | 0 | Direct |
49899,49854
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain | 0 | Direct |
49363,56300
49363 - Purple acid phosphatase, N-terminal domain
56300 - Metallo-dependent phosphatases | 0 | Direct |
50044,51695
50044 - SH3-domain
51695 - PLC-like phosphodiesterases | 0 | Direct |
54001,143791
54001 - Cysteine proteinases
143791 - DUSP-like | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
54001,55205
54001 - Cysteine proteinases
55205 - EPT/RTPC-like | 0 | Direct |
56487,57424
56487 - SRCR-like
57424 - LDL receptor-like module | 0 | Direct |
49344,49344
49344 - CBD9-like
49344 - CBD9-like | 0 | Direct |
57440,57196
57440 - Kringle-like
57196 - EGF/Laminin | 0 | Direct |
50199,63748
50199 - Staphylococcal nuclease
63748 - Tudor/PWWP/MBT | 0 | Direct |
52317,141986
52317 - Class I glutamine amidotransferase-like
141986 - LD-carboxypeptidase A C-terminal domain-like | 0 | Direct |
52335,53927
52335 - Methylglyoxal synthase-like
53927 - Cytidine deaminase-like | 0 | Direct |
54637,52151
54637 - Thioesterase/thiol ester dehydrase-isomerase
52151 - FabD/lysophospholipase-like | 0 | Direct |
49562,52151
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
52151 - FabD/lysophospholipase-like | 0 | Direct |
52266,49818
52266 - SGNH hydrolase
49818 - Viral protein domain | 0 | Direct |
49785,63446
49785 - Galactose-binding domain-like
63446 - Type I dockerin domain | 0 | Direct |
82708,53098
82708 - R3H domain
53098 - Ribonuclease H-like | 0 | Direct |
55920,46785
55920 - Creatinase/aminopeptidase
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
51011,51445
51011 - Glycosyl hydrolase domain
51445 - (Trans)glycosidases | 0 | Direct |
57196,50494
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
49785,51445
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases | 0 | Direct |
52200,52540
52200 - Toll/Interleukin receptor TIR domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47769,52200
47769 - SAM/Pointed domain
52200 - Toll/Interleukin receptor TIR domain | 0 | Direct |
143076,101816
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0 | Direct |
49899,49599
49899 - Concanavalin A-like lectins/glucanases
49599 - TRAF domain-like | 0 | Direct |
51445,54556
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
57756,50630
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
56300,47473
56300 - Metallo-dependent phosphatases
47473 - EF-hand | 0 | Direct |
51011,50370
51011 - Glycosyl hydrolase domain
50370 - Ricin B-like lectins | 0 | Direct |
48208,63446
48208 - Six-hairpin glycosidases
63446 - Type I dockerin domain | 0 | Direct |
57630,57196
57630 - GLA-domain
57196 - EGF/Laminin | 0 | Direct |
49265,49452
49265 - Fibronectin type III
49452 - Starch-binding domain-like | 0 | Direct |
143791,54236
143791 - DUSP-like
54236 - Ubiquitin-like | 0 | Direct |
57630,57440
57630 - GLA-domain
57440 - Kringle-like | 0 | Direct |
51283,46919
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
53474,49785
53474 - alpha/beta-Hydrolases
49785 - Galactose-binding domain-like | 0 | Direct |
52151,52151
52151 - FabD/lysophospholipase-like
52151 - FabD/lysophospholipase-like | 0 | Direct |
51445,64571
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering | 0 | Direct |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
46938,52087
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain | 0 | Direct |
53756,53067
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
53067 - Actin-like ATPase domain | 0 | Direct |
51445,49384
51445 - (Trans)glycosidases
49384 - Carbohydrate-binding domain | 0 | Direct |
55486,58091
55486 - Metalloproteases ("zincins"), catalytic domain
58091 - Clostridium neurotoxins, "coiled-coil" domain | 0 | Direct |
52266,103515
52266 - SGNH hydrolase
103515 - Autotransporter | 0 | Direct |
55781,109604
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | Direct |
57016,53955
57016 - Plant lectins/antimicrobial peptides
53955 - Lysozyme-like | 0 | Direct |
47090,47090
47090 - PGBD-like
47090 - PGBD-like | 0 | Direct |
48371,47769
48371 - ARM repeat
47769 - SAM/Pointed domain | 0 | Direct |
47090,55486
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain | 0 | Direct |
52540,-8
52540 - P-loop containing nucleoside triphosphate hydrolases
-8 - ECOD | 0 | Direct |
55154,56091
55154 - CYTH-like phosphatases
56091 - DNA ligase/mRNA capping enzyme, catalytic domain | 0 | Direct |
88633,50494
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases | 0 | Direct |
54211,54637
54211 - Ribosomal protein S5 domain 2-like
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
53927,53927
53927 - Cytidine deaminase-like
53927 - Cytidine deaminase-like | 0 | Direct |
52058,56219
52058 - L domain-like
56219 - DNase I-like | 0 | Direct |
47986,52129
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
101816,144246
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0 | Direct |
49503,110083
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain | 0 | Direct |
49562,56024
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
56024 - Phospholipase D/nuclease | 0 | Direct |
46785,47819
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | Direct |
54211,54211
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
48208,49384
48208 - Six-hairpin glycosidases
49384 - Carbohydrate-binding domain | 0 | Direct |
52540,57756
52540 - P-loop containing nucleoside triphosphate hydrolases
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
74924,54001
74924 - Cap-Gly domain
54001 - Cysteine proteinases | 0 | Direct |
47233,52799
47233 - Bacterial GAP domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
49899,49384
49899 - Concanavalin A-like lectins/glucanases
49384 - Carbohydrate-binding domain | 0 | Direct |
63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
52025,53187
52025 - PA domain
53187 - Zn-dependent exopeptidases | 0 | Direct |
49854,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | Direct |
50494,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like | 0 | Direct |
141734,101386
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases | 0 | Direct |
82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
110083,55909
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
50370,50370
50370 - Ricin B-like lectins
50370 - Ricin B-like lectins | 0 | Direct |
159672,159664
159672 - CbiG N-terminal domain-like
159664 - CobE/GbiG C-terminal domain-like | 0 | Direct |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
56487,50494
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | Direct |
50156,52799
50156 - PDZ domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
53649,54060
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0 | Direct |
55486,50923
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
55486,49899
55486 - Metalloproteases ("zincins"), catalytic domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
56784,53474
56784 - HAD-like
53474 - alpha/beta-Hydrolases | 0 | Direct |
51206,51206
51206 - cAMP-binding domain-like
51206 - cAMP-binding domain-like | 0 | Direct |
53335,142877
53335 - S-adenosyl-L-methionine-dependent methyltransferases
142877 - EndoU-like | 0 | Direct |
51445,49344
51445 - (Trans)glycosidases
49344 - CBD9-like | 0 | Direct |
56784,56784
56784 - HAD-like
56784 - HAD-like | 0 | Direct |
52172,52738
52172 - CheY-like
52738 - Methylesterase CheB, C-terminal domain | 0 | Direct |
56672,88633
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
57440,57440
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | Direct |
57535,50494
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
53067,109604
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | Direct |
50630,56672
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | Direct |
56601,48403
56601 - beta-lactamase/transpeptidase-like
48403 - Ankyrin repeat | 0 | Direct |
55550,52799
55550 - SH2 domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
47473,51695
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
53474,53474
53474 - alpha/beta-Hydrolases
53474 - alpha/beta-Hydrolases | 0 | Direct |
52540,54211
52540 - P-loop containing nucleoside triphosphate hydrolases
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
57424,50494
57424 - LDL receptor-like module
50494 - Trypsin-like serine proteases | 0 | Direct |
57630,57184
57630 - GLA-domain
57184 - Growth factor receptor domain | 0 | Direct |
54001,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
56300,56300
56300 - Metallo-dependent phosphatases
56300 - Metallo-dependent phosphatases | 0 | Direct |
50729,56024
50729 - PH domain-like
56024 - Phospholipase D/nuclease | 0 | Direct |
116846,52540
116846 - MIT domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50916,46785
50916 - Rap30/74 interaction domains
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
55486,82895
55486 - Metalloproteases ("zincins"), catalytic domain
82895 - TSP-1 type 1 repeat | 0 | Direct |
101148,51126
101148 - Plant invertase/pectin methylesterase inhibitor
51126 - Pectin lyase-like | 0 | Direct |
47781,46929
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
160481,160481
160481 - BRK domain-like
160481 - BRK domain-like | 0 | Direct |
49879,54197
49879 - SMAD/FHA domain
54197 - HIT-like | 0 | Direct |
56219,54928
56219 - DNase I-like
54928 - RNA-binding domain, RBD | 0 | Direct |
81296,48208
81296 - E set domains
48208 - Six-hairpin glycosidases | 0 | Direct |
57424,56487
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | Direct |
50249,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
52540,49899
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
158702,81296
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | Direct |
56300,55816
56300 - Metallo-dependent phosphatases
55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0 | Direct |
56731,52540
56731 - DNA primase core
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55545,51445
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases | 0 | Direct |
46946,57716
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
57492,74650
57492 - Trefoil
74650 - Galactose mutarotase-like | 0 | Direct |
53774,48403
53774 - Glutaminase/Asparaginase
48403 - Ankyrin repeat | 0 | Direct |
56784,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
49452,52799
49452 - Starch-binding domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | Direct |
48371,54001
48371 - ARM repeat
54001 - Cysteine proteinases | 0 | Direct |
74650,51445
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
53335,52949
53335 - S-adenosyl-L-methionine-dependent methyltransferases
52949 - Macro domain-like | 0 | Direct |
57440,50494
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
50199,50199
50199 - Staphylococcal nuclease
50199 - Staphylococcal nuclease | 0 | Direct |
54001,53098
54001 - Cysteine proteinases
53098 - Ribonuclease H-like | 0 | Direct |
54236,54001
54236 - Ubiquitin-like
54001 - Cysteine proteinases | 0 | Direct |
49854,49899
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
52540,89043
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
54001,144232
54001 - Cysteine proteinases
144232 - HIT/MYND zinc finger-like | 0 | Direct |
143503,54001
143503 - PUG domain-like
54001 - Cysteine proteinases | 0 | Direct |
81606,81601
81606 - PP2C-like
81601 - Protein serine/threonine phosphatase 2C, C-terminal domain | 0 | Direct |
88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
158702,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46785,158702
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
50447,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
54585,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
117100,49785
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like | 0 | Direct |
54160,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51445,57180
51445 - (Trans)glycosidases
57180 - Cellulose-binding domain | 0 | Direct |
51283,51283
51283 - dUTPase-like
51283 - dUTPase-like | 0 | Direct |
50993,53474
50993 - Peptidase/esterase 'gauge' domain
53474 - alpha/beta-Hydrolases | 0 | Direct |
51011,49265
51011 - Glycosyl hydrolase domain
49265 - Fibronectin type III | 0 | Direct |
49464,53187
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases | 0 | Direct |
56672,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | Direct |
51283,50630
51283 - dUTPase-like
50630 - Acid proteases | 0 | Direct |
47943,47353
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | Direct |
48537,49723
48537 - Phospholipase C/P1 nuclease
49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0 | Direct |
50249,47781
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like | 0 | Direct |
109715,52799
109715 - DEK C-terminal domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
55464,52540
55464 - Origin of replication-binding domain, RBD-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53955,54106
53955 - Lysozyme-like
54106 - LysM domain | 0 | Direct |
53187,55031
53187 - Zn-dependent exopeptidases
55031 - Bacterial exopeptidase dimerisation domain | 0 | Direct |
53300,100939
53300 - vWA-like
100939 - SPOC domain-like | 0 | Direct |
50729,47473
50729 - PH domain-like
47473 - EF-hand | 0 | Direct |
48208,49452
48208 - Six-hairpin glycosidases
49452 - Starch-binding domain-like | 0 | Direct |
50729,52799
50729 - PH domain-like
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
74924,74924
74924 - Cap-Gly domain
74924 - Cap-Gly domain | 0 | Direct |
54236,56784
54236 - Ubiquitin-like
56784 - HAD-like | 0 | Direct |
159936,53335
159936 - NSP3A-like
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0 | Direct |
52540,48403
52540 - P-loop containing nucleoside triphosphate hydrolases
48403 - Ankyrin repeat | 0 | Direct |
143791,143791
143791 - DUSP-like
143791 - DUSP-like | 0 | Direct |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
52768,52768
52768 - Arginase/deacetylase
52768 - Arginase/deacetylase | 0 | Direct |
54160,54160
54160 - Chromo domain-like
54160 - Chromo domain-like | 0 | Direct |
48403,52151
48403 - Ankyrin repeat
52151 - FabD/lysophospholipase-like | 0 | Direct |
50692,54585
50692 - ADC-like
54585 - Cdc48 domain 2-like | 0 | Direct |
48024,52540
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49785,49303
49785 - Galactose-binding domain-like
49303 - beta-Galactosidase/glucuronidase domain | 0 | Direct |
49854,57196
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin | 0 | Direct |
52540,54928
52540 - P-loop containing nucleoside triphosphate hydrolases
54928 - RNA-binding domain, RBD | 0 | Direct |
52540,55144
52540 - P-loop containing nucleoside triphosphate hydrolases
55144 - LigT-like | 0 | Direct |
55821,142695
55821 - YrdC/RibB
142695 - RibA-like | 0 | Direct |
47986,47986
47986 - DEATH domain
47986 - DEATH domain | 0 | Direct |
51695,49562
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
52317,51011
52317 - Class I glutamine amidotransferase-like
51011 - Glycosyl hydrolase domain | 0 | Direct |
49384,55545
49384 - Carbohydrate-binding domain
55545 - beta-N-acetylhexosaminidase-like domain | 0 | Direct |
63433,56529
63433 - Fumarylacetoacetate hydrolase, FAH, N-terminal domain
56529 - FAH | 0 | Direct |
52540,53254
52540 - P-loop containing nucleoside triphosphate hydrolases
53254 - Phosphoglycerate mutase-like | 3.548e-16 | Direct |
50156,50156
50156 - PDZ domain-like
50156 - PDZ domain-like | 5.316e-16 | Direct |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.00000000000006338 | Direct |
54106,54106
54106 - LysM domain
54106 - LysM domain | 0.000000000001862 | Direct |
88688,74650
88688 - Families 57/38 glycoside transferase middle domain
74650 - Galactose mutarotase-like | 0.00000000002664 | Direct |
51735,52283
51735 - NAD(P)-binding Rossmann-fold domains
52283 - Formate/glycerate dehydrogenase catalytic domain-like | 0.0000000000457 | Direct |
53955,56601
53955 - Lysozyme-like
56601 - beta-lactamase/transpeptidase-like | 0.0000000000457 | Direct |
53927,53597
53927 - Cytidine deaminase-like
53597 - Dihydrofolate reductase-like | 0.0000000001248 | Direct |
57756,57756
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0.00000001244 | Direct |
55550,55550
55550 - SH2 domain
55550 - SH2 domain | 0.00000001315 | Direct |
51445,51445
51445 - (Trans)glycosidases
51445 - (Trans)glycosidases | 0.00000002724 | Direct |
52799,49562
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.00000007459 | Direct |
64268,50729
64268 - PX domain
50729 - PH domain-like | 0.0000006634 | Direct |
54637,54637
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0.000002298 | Direct |
51011,49452
51011 - Glycosyl hydrolase domain
49452 - Starch-binding domain-like | 0.00001607 | Direct |
55073,141868
55073 - Nucleotide cyclase
141868 - EAL domain-like | 0.00001607 | Direct |
48403,52540
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00002349 | Direct |
51197,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.00002356 | Direct |
52540,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0.00002757 | Direct |
160467,50891
160467 - PH0987 N-terminal domain-like
50891 - Cyclophilin-like | 0.00007897 | Direct |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.00008918 | Direct |
52335,51556
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.00009526 | Direct |
63748,50199
63748 - Tudor/PWWP/MBT
50199 - Staphylococcal nuclease | 0.0001035 | Direct |
49899,50939
49899 - Concanavalin A-like lectins/glucanases
50939 - Sialidases | 0.0003875 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0.0004372 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0.001462 | Inherited |
49785,81296
49785 - Galactose-binding domain-like
81296 - E set domains | 0.0019 | Inherited |
90209,90209
90209 - Ran binding protein zinc finger-like
90209 - Ran binding protein zinc finger-like | 0.001905 | Inherited |
56712,51294
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0.001905 | Inherited |
52317,52440
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.002807 | Inherited |
47031,50729
47031 - Second domain of FERM
50729 - PH domain-like | 0.005052 | Inherited |
47336,53474
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.007395 | Inherited |
51294,55608
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0.01145 | Inherited |
53474,53335
53474 - alpha/beta-Hydrolases
53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.01954 | Inherited |
81296,51445
81296 - E set domains
51445 - (Trans)glycosidases | 0.02869 | Inherited |
100950,100950
100950 - NagB/RpiA/CoA transferase-like
100950 - NagB/RpiA/CoA transferase-like | 0.02897 | Inherited |
81301,81271
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.05535 | Inherited |
55608,52540
55608 - Homing endonucleases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.06378 | Inherited |
55945,48150
55945 - TATA-box binding protein-like
48150 - DNA-glycosylase | 0.09636 | Inherited |
109604,81301
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase | 0.1308 | Inherited |
54236,54236
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0.1352 | Inherited |
74650,48208
74650 - Galactose mutarotase-like
48208 - Six-hairpin glycosidases | 0.2529 | Inherited |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.277 | Inherited |
53756,56784
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
56784 - HAD-like | 0.2921 | Inherited |
52317,51366
52317 - Class I glutamine amidotransferase-like
51366 - Ribulose-phoshate binding barrel | 0.3097 | Inherited |
56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0.3566 | Inherited |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0.3982 | Inherited |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0.5818 | Inherited |
49785,57184
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0.6528 | Inherited |
51735,51735
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.7921 | Inherited |
51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.807 | Inherited |
52021,52317
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like | 1 | Inherited |
56091,50249
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 1 | Inherited |
53098,56672
53098 - Ribonuclease H-like
56672 - DNA/RNA polymerases | 1 | Inherited |
56784,81665
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 1 | Inherited |
53067,53067
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain | 1 | Inherited |
56059,52335
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | Inherited |
48108,52440
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | Inherited |
50129,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains | 1 | Inherited |
51735,56327
51735 - NAD(P)-binding Rossmann-fold domains
56327 - LDH C-terminal domain-like | 1 | Inherited |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
52151,55048
52151 - FabD/lysophospholipase-like
55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | Inherited |
53901,53901
53901 - Thiolase-like
53901 - Thiolase-like | 1 | Inherited |
52518,52467
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain | 1 | Inherited |
48239,48576
48239 - Terpenoid cyclases/Protein prenyltransferases
48576 - Terpenoid synthases | 1 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | Inherited |
56059,48108
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
52467,52518
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (SPEC level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57603,57440,57440
57603 - FnI-like domain
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
89043,50494,56672
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
53092,53092,55920
53092 - Creatinase/prolidase N-terminal domain
53092 - Creatinase/prolidase N-terminal domain
55920 - Creatinase/aminopeptidase | 0 | DIRECT |
90188,53649,54060
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0 | DIRECT |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
54637,54637,55961
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase
55961 - Bet v1-like | 0 | DIRECT |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
51445,49303,74650
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain
74650 - Galactose mutarotase-like | 0 | DIRECT |
57424,57424,50494
57424 - LDL receptor-like module
57424 - LDL receptor-like module
50494 - Trypsin-like serine proteases | 0 | DIRECT |
54001,49758,47473
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | DIRECT |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
54106,54106,54106
54106 - LysM domain
54106 - LysM domain
54106 - LysM domain | 0 | DIRECT |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | DIRECT |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
50729,56024,56024
50729 - PH domain-like
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
56371,50370,50370
56371 - Ribosome inactivating proteins (RIP)
50370 - Ricin B-like lectins
50370 - Ricin B-like lectins | 0 | DIRECT |
51278,51338,51556
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | DIRECT |
82708,53098,54928
82708 - R3H domain
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | DIRECT |
51445,49303,49303
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain
49303 - beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
51283,46919,53098
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
49384,55545,51445
49384 - Carbohydrate-binding domain
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases | 0 | DIRECT |
49854,49899,49854
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
47090,55486,57440
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like | 0 | DIRECT |
50630,56672,53098
50630 - Acid proteases
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | DIRECT |
49265,49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
50630,56672,46919
50630 - Acid proteases
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | DIRECT |
51445,51011,49265
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
49265 - Fibronectin type III | 0 | DIRECT |
52540,52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | DIRECT |
53187,49464,53187
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56784,54211,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
50494,52540,89043
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
49854,57424,56487
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | DIRECT |
49562,54236,54236
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | DIRECT |
57630,57196,57196
57630 - GLA-domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
56672,53098,51283
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | DIRECT |
55550,55550,50044
55550 - SH2 domain
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
49785,51445,64571
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering | 0 | DIRECT |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
50494,52540,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53955,54106,54106
53955 - Lysozyme-like
54106 - LysM domain
54106 - LysM domain | 0 | DIRECT |
50199,63748,50199
50199 - Staphylococcal nuclease
63748 - Tudor/PWWP/MBT
50199 - Staphylococcal nuclease | 0 | DIRECT |
143076,101816,144246
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0 | DIRECT |
49899,49854,57424
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | DIRECT |
51011,117100,49785
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like | 0 | DIRECT |
56568,47233,52799
56568 - Non-globular alpha+beta subunits of globular proteins
47233 - Bacterial GAP domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
57756,51283,50630
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like
50630 - Acid proteases | 0 | DIRECT |
64268,50729,56024
64268 - PX domain
50729 - PH domain-like
56024 - Phospholipase D/nuclease | 0 | DIRECT |
55545,51445,81296
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases
81296 - E set domains | 0 | DIRECT |
47836,47943,47353
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | DIRECT |
49785,49785,51445
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases | 0 | DIRECT |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | DIRECT |
51197,52540,56672
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
47473,51695,49562
47473 - EF-hand
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
49854,49854,50494
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
51197,52540,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56601,50886,50886
56601 - beta-lactamase/transpeptidase-like
50886 - D-aminopeptidase, middle and C-terminal domains
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | DIRECT |
46785,158702,81296
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | DIRECT |
49464,53187,49464
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | DIRECT |
51445,52317,51011
51445 - (Trans)glycosidases
52317 - Class I glutamine amidotransferase-like
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
57535,57535,53300
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
53300 - vWA-like | 0 | DIRECT |
58091,49899,50386
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases
50386 - STI-like | 0 | DIRECT |
51445,64571,64571
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering
64571 - Cellulose docking domain, dockering | 0 | DIRECT |
57196,57196,50494
57196 - EGF/Laminin
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
51445,49785,49785
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | DIRECT |
55550,55550,52799
55550 - SH2 domain
55550 - SH2 domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | DIRECT |
56672,53098,46919
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
50447,54980,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
54111,51278,51338
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | DIRECT |
47353,57756,50630
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | DIRECT |
54106,54106,54001
54106 - LysM domain
54106 - LysM domain
54001 - Cysteine proteinases | 0 | DIRECT |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | DIRECT |
50044,51695,49562
50044 - SH3-domain
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57630,57440,57440
57630 - GLA-domain
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
56672,53098,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | DIRECT |
54001,143791,143791
54001 - Cysteine proteinases
143791 - DUSP-like
143791 - DUSP-like | 0 | DIRECT |
52540,48403,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56672,52540,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50494,56672,88633
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
81296,48208,63446
81296 - E set domains
48208 - Six-hairpin glycosidases
63446 - Type I dockerin domain | 0 | DIRECT |
51445,49785,63446
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like
63446 - Type I dockerin domain | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
53300,100939,101420
53300 - vWA-like
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | DIRECT |
81624,46946,57716
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
143503,54001,49785
143503 - PUG domain-like
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | DIRECT |
52540,52156,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
52156 - Initiation factor IF2/eIF5b, domain 3
50447 - Translation proteins | 0 | DIRECT |
53067,53067,109604
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | DIRECT |
51445,51011,117100
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3 | 0 | DIRECT |
52540,46785,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | DIRECT |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | DIRECT |
49785,81296,48208
49785 - Galactose-binding domain-like
81296 - E set domains
48208 - Six-hairpin glycosidases | 0 | DIRECT |
88633,50494,52540
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | DIRECT |
49899,48726,49265
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | DIRECT |
47769,47769,52200
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
52200 - Toll/Interleukin receptor TIR domain | 0 | DIRECT |
57756,57756,51283
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0 | DIRECT |
52540,49899,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
56487,57424,57424
56487 - SRCR-like
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
54211,54211,54637
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | DIRECT |
50494,52540,56672
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | DIRECT |
55486,57440,57440
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
69065,69065,54768
69065 - RNase III domain-like
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
51283,50630,56672
51283 - dUTPase-like
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
52540,54980,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
49854,49854,57424
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | DIRECT |
52200,52540,46785
52200 - Toll/Interleukin receptor TIR domain
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
56672,53098,50122
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
57492,74650,51445
57492 - Trefoil
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | DIRECT |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
53300,100939,68906
53300 - vWA-like
100939 - SPOC domain-like
68906 - SAP domain | 0 | DIRECT |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
52540,56712,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57630,57196,50494
57630 - GLA-domain
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | DIRECT |
81296,51445,54556
81296 - E set domains
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | DIRECT |
56672,46919,53098
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
50249,52540,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50199,50199,50199
50199 - Staphylococcal nuclease
50199 - Staphylococcal nuclease
50199 - Staphylococcal nuclease | 0 | DIRECT |
55486,58091,49899
55486 - Metalloproteases ("zincins"), catalytic domain
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
48371,47769,47769
48371 - ARM repeat
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
57424,56487,50494
57424 - LDL receptor-like module
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
49785,49303,51445
49785 - Galactose-binding domain-like
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases | 0 | DIRECT |
49303,51445,49303
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain | 0 | DIRECT |
57535,53300,50494
57535 - Complement control module/SCR domain
53300 - vWA-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
53098,51283,46919
53098 - Ribonuclease H-like
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | DIRECT |
81761,53474,49785
81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
53474 - alpha/beta-Hydrolases
49785 - Galactose-binding domain-like | 0 | DIRECT |
49785,51445,49344
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases
49344 - CBD9-like | 0 | DIRECT |
51445,51011,50370
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
50370 - Ricin B-like lectins | 0 | DIRECT |
47353,57756,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
100895,56487,57424
100895 - Kazal-type serine protease inhibitors
56487 - SRCR-like
57424 - LDL receptor-like module | 0 | DIRECT |
88633,88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
82671,49854,49854
82671 - SEA domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
49854,57424,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | DIRECT |
50199,50199,63748
50199 - Staphylococcal nuclease
50199 - Staphylococcal nuclease
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
48024,52540,51294
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
55545,51445,140657
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like | 0 | DIRECT |
53098,46919,53098
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | DIRECT |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | DIRECT |
56024,56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | DIRECT |
50494,50156,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | DIRECT |
52799,56091,50249
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | DIRECT |
50249,47781,46929
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | DIRECT |
57630,57184,50494
57630 - GLA-domain
57184 - Growth factor receptor domain
50494 - Trypsin-like serine proteases | 0 | DIRECT |
55781,55781,109604
55781 - GAF domain-like
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | DIRECT |
47943,47353,57756
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
82671,57424,49854
82671 - SEA domain
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
55550,50044,51695
55550 - SH2 domain
50044 - SH3-domain
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | DIRECT |
81324,52799,49562
81324 - Voltage-gated potassium channels
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
46938,52087,52799
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
55486,49899,49599
55486 - Metalloproteases ("zincins"), catalytic domain
49899 - Concanavalin A-like lectins/glucanases
49599 - TRAF domain-like | 0 | DIRECT |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | DIRECT |
57756,50630,56672
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | DIRECT |
46785,158702,52540
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
158702,52540,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46919,53098,50122
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | DIRECT |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | DIRECT |
52540,89043,50494
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | DIRECT |
51445,140657,49785
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
141734,101386,53720
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | DIRECT |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
55781,55781,55781
55781 - GAF domain-like
55781 - GAF domain-like
55781 - GAF domain-like | 0 | DIRECT |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
117100,49785,49785
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
54001,88633,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | DIRECT |
51011,51445,51011
51011 - Glycosyl hydrolase domain
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | DIRECT |
52540,52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | DIRECT |
51445,49344,49344
51445 - (Trans)glycosidases
49344 - CBD9-like
49344 - CBD9-like | 0 | DIRECT |
140367,143076,101816
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0 | DIRECT |
52540,52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
57424,49854,49899
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53098,47819,47819
53098 - Ribonuclease H-like
47819 - HRDC-like
47819 - HRDC-like | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | DIRECT |
88713,88688,74650
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain
74650 - Galactose mutarotase-like | 0.00000000002664 | DIRECT |
52283,51735,52283
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains
52283 - Formate/glycerate dehydrogenase catalytic domain-like | 0.0000000002262 | DIRECT |
52540,52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0.00000007213 | DIRECT |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.000001155 | DIRECT |
52335,51556,51338
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0.000003267 | DIRECT |
51445,51011,49452
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
49452 - Starch-binding domain-like | 0.00001607 | DIRECT |
51735,47336,53474
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.00007897 | DIRECT |
56059,52335,51556
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.00009526 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0.0004372 | DIRECT |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.001905 | INHERITED FROM: Acting on acid anhydrides || Acting on ATP; involved in cellular and subcellular movement |
52540,51294,55608
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0.002314 | INHERITED FROM: Acting on acid anhydrides || Acting on ATP; involved in cellular and subcellular movement || DNA helicase |
52317,52440,56059
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.002807 | INHERITED FROM: In cyclic amides || Dihydroorotase || Acting on carbon-nitrogen bonds, other than peptide bonds |
52021,52317,52440
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.002807 | INHERITED FROM: In cyclic amides || Dihydroorotase || Acting on carbon-nitrogen bonds, other than peptide bonds |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.008046 | INHERITED FROM: Acting on ester bonds || Protein-tyrosine-phosphatase || Phosphoric monoester hydrolases |
81296,51445,51011
81296 - E set domains
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0.03646 | INHERITED FROM: Limit dextrin alpha-1,6-maltotetraose-hydrolase || Isoamylase || 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase || Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds || Glycosylases || Pullulanase || Neopullulanase |
109604,81301,81271
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.05535 | INHERITED FROM: Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase || Acting on ester bonds || Diphosphoric monoester hydrolases |
50129,51735,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.1182 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Acting on ester bonds || Thiolester hydrolases |
51735,51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.7206 | INHERITED FROM: Oleoyl-[acyl-carrier-protein] hydrolase || Thiolester hydrolases |
48108,52440,56059
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | INHERITED FROM: In cyclic amides || Dihydroorotase |
52440,56059,48108
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | INHERITED FROM: In cyclic amides || Dihydroorotase |
52518,52467,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 1 | INHERITED FROM: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) || Acting on carbon-carbon bonds |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | INHERITED FROM: Protein-tyrosine-phosphatase || Phosphoric monoester hydrolases |
52440,56059,52335
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | INHERITED FROM: In cyclic amides || Dihydroorotase |
56059,48108,52440
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | INHERITED FROM: In cyclic amides || Dihydroorotase |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57603,57440,57440
57603 - FnI-like domain
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
89043,50494,56672
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases | 0 | Direct |
53092,53092,55920
53092 - Creatinase/prolidase N-terminal domain
53092 - Creatinase/prolidase N-terminal domain
55920 - Creatinase/aminopeptidase | 0 | Direct |
90188,53649,54060
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like
54060 - His-Me finger endonucleases | 0 | Direct |
49854,57535,57535
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
54637,54637,55961
54637 - Thioesterase/thiol ester dehydrase-isomerase
54637 - Thioesterase/thiol ester dehydrase-isomerase
55961 - Bet v1-like | 0 | Direct |
57535,57535,50494
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
50494 - Trypsin-like serine proteases | 0 | Direct |
51445,49303,74650
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain
74650 - Galactose mutarotase-like | 0 | Direct |
57424,57424,50494
57424 - LDL receptor-like module
57424 - LDL receptor-like module
50494 - Trypsin-like serine proteases | 0 | Direct |
54001,49758,47473
54001 - Cysteine proteinases
49758 - Calpain large subunit, middle domain (domain III)
47473 - EF-hand | 0 | Direct |
51338,51556,51338
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
54106,54106,54106
54106 - LysM domain
54106 - LysM domain
54106 - LysM domain | 0 | Direct |
90188,90188,53649
90188 - Somatomedin B domain
90188 - Somatomedin B domain
53649 - Alkaline phosphatase-like | 0 | Direct |
74650,51445,51011
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
50729,56024,56024
50729 - PH domain-like
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
56371,50370,50370
56371 - Ribosome inactivating proteins (RIP)
50370 - Ricin B-like lectins
50370 - Ricin B-like lectins | 0 | Direct |
51278,51338,51556
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases
51556 - Metallo-dependent hydrolases | 0 | Direct |
82708,53098,54928
82708 - R3H domain
53098 - Ribonuclease H-like
54928 - RNA-binding domain, RBD | 0 | Direct |
51445,49303,49303
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain
49303 - beta-Galactosidase/glucuronidase domain | 0 | Direct |
51283,46919,53098
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
49384,55545,51445
49384 - Carbohydrate-binding domain
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases | 0 | Direct |
49854,49899,49854
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain | 0 | Direct |
47090,55486,57440
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like | 0 | Direct |
50630,56672,53098
50630 - Acid proteases
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like | 0 | Direct |
49265,49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
50630,56672,46919
50630 - Acid proteases
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
52025,53187,47672
52025 - PA domain
53187 - Zn-dependent exopeptidases
47672 - Transferrin receptor-like dimerisation domain | 0 | Direct |
51445,51011,49265
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
49265 - Fibronectin type III | 0 | Direct |
52540,52540,47370
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47370 - Bromodomain | 0 | Direct |
53187,49464,53187
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases | 0 | Direct |
54585,52540,52540
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56784,54211,54211
56784 - HAD-like
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
50494,52540,89043
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
49854,57424,56487
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module
56487 - SRCR-like | 0 | Direct |
49562,54236,54236
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
54236 - Ubiquitin-like
54236 - Ubiquitin-like | 0 | Direct |
57630,57196,57196
57630 - GLA-domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
56672,53098,51283
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
51283 - dUTPase-like | 0 | Direct |
55550,55550,50044
55550 - SH2 domain
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
49785,51445,64571
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering | 0 | Direct |
57535,57535,57535
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain | 0 | Direct |
50494,52540,52540
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53955,54106,54106
53955 - Lysozyme-like
54106 - LysM domain
54106 - LysM domain | 0 | Direct |
50199,63748,50199
50199 - Staphylococcal nuclease
63748 - Tudor/PWWP/MBT
50199 - Staphylococcal nuclease | 0 | Direct |
143076,101816,144246
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9
144246 - Coronavirus NSP10-like | 0 | Direct |
49899,49854,57424
49899 - Concanavalin A-like lectins/glucanases
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | Direct |
51011,117100,49785
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like | 0 | Direct |
56568,47233,52799
56568 - Non-globular alpha+beta subunits of globular proteins
47233 - Bacterial GAP domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
57756,51283,50630
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like
50630 - Acid proteases | 0 | Direct |
64268,50729,56024
64268 - PX domain
50729 - PH domain-like
56024 - Phospholipase D/nuclease | 0 | Direct |
55545,51445,81296
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases
81296 - E set domains | 0 | Direct |
47836,47943,47353
47836 - Retroviral matrix proteins
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like | 0 | Direct |
49785,49785,51445
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases | 0 | Direct |
57196,49854,57535
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain
57535 - Complement control module/SCR domain | 0 | Direct |
51197,52540,56672
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
47473,51695,49562
47473 - EF-hand
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
49854,49854,50494
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain
50494 - Trypsin-like serine proteases | 0 | Direct |
51197,52540,52540
51197 - Clavaminate synthase-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56601,50886,50886
56601 - beta-lactamase/transpeptidase-like
50886 - D-aminopeptidase, middle and C-terminal domains
50886 - D-aminopeptidase, middle and C-terminal domains | 0 | Direct |
46785,158702,81296
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
81296 - E set domains | 0 | Direct |
49464,53187,49464
49464 - Carboxypeptidase regulatory domain-like
53187 - Zn-dependent exopeptidases
49464 - Carboxypeptidase regulatory domain-like | 0 | Direct |
51445,52317,51011
51445 - (Trans)glycosidases
52317 - Class I glutamine amidotransferase-like
51011 - Glycosyl hydrolase domain | 0 | Direct |
49785,49785,49785
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
57535,57535,53300
57535 - Complement control module/SCR domain
57535 - Complement control module/SCR domain
53300 - vWA-like | 0 | Direct |
58091,49899,50386
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases
50386 - STI-like | 0 | Direct |
51445,64571,64571
51445 - (Trans)glycosidases
64571 - Cellulose docking domain, dockering
64571 - Cellulose docking domain, dockering | 0 | Direct |
57196,57196,50494
57196 - EGF/Laminin
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
51445,49785,49785
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
49503,110083,55909
49503 - Cupredoxins
110083 - Peptidylarginine deiminase Pad4, middle domain
55909 - Pentein | 0 | Direct |
55550,55550,52799
55550 - SH2 domain
55550 - SH2 domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
82895,82895,82895
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat
82895 - TSP-1 type 1 repeat | 0 | Direct |
56672,53098,46919
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
54768,54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
50447,54980,54980
50447 - Translation proteins
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
54111,51278,51338
54111 - Urease, gamma-subunit
51278 - Urease, beta-subunit
51338 - Composite domain of metallo-dependent hydrolases | 0 | Direct |
47353,57756,50630
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases | 0 | Direct |
54106,54106,54001
54106 - LysM domain
54106 - LysM domain
54001 - Cysteine proteinases | 0 | Direct |
47090,55486,50923
47090 - PGBD-like
55486 - Metalloproteases ("zincins"), catalytic domain
50923 - Hemopexin-like domain | 0 | Direct |
50044,51695,49562
50044 - SH3-domain
51695 - PLC-like phosphodiesterases
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57630,57440,57440
57630 - GLA-domain
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
56672,53098,53098
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
53098 - Ribonuclease H-like | 0 | Direct |
54001,143791,143791
54001 - Cysteine proteinases
143791 - DUSP-like
143791 - DUSP-like | 0 | Direct |
52540,48403,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
48403 - Ankyrin repeat
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56672,52540,52540
56672 - DNA/RNA polymerases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50494,56672,88633
50494 - Trypsin-like serine proteases
56672 - DNA/RNA polymerases
88633 - Positive stranded ssRNA viruses | 0 | Direct |
81296,48208,63446
81296 - E set domains
48208 - Six-hairpin glycosidases
63446 - Type I dockerin domain | 0 | Direct |
51445,49785,63446
51445 - (Trans)glycosidases
49785 - Galactose-binding domain-like
63446 - Type I dockerin domain | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
53300,100939,101420
53300 - vWA-like
100939 - SPOC domain-like
101420 - C-terminal domain of Ku80 | 0 | Direct |
81624,46946,57716
81624 - N-terminal domain of MutM-like DNA repair proteins
46946 - S13-like H2TH domain
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
143503,54001,49785
143503 - PUG domain-like
54001 - Cysteine proteinases
49785 - Galactose-binding domain-like | 0 | Direct |
52540,52156,50447
52540 - P-loop containing nucleoside triphosphate hydrolases
52156 - Initiation factor IF2/eIF5b, domain 3
50447 - Translation proteins | 0 | Direct |
53067,53067,109604
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
109604 - HD-domain/PDEase-like | 0 | Direct |
51445,51011,117100
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
117100 - Beta-galactosidase LacA, domain 3 | 0 | Direct |
52540,46785,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
47819 - HRDC-like | 0 | Direct |
54160,54160,52540
54160 - Chromo domain-like
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
63737,55486,48371
63737 - Leukotriene A4 hydrolase N-terminal domain
55486 - Metalloproteases ("zincins"), catalytic domain
48371 - ARM repeat | 0 | Direct |
49785,81296,48208
49785 - Galactose-binding domain-like
81296 - E set domains
48208 - Six-hairpin glycosidases | 0 | Direct |
88633,50494,52540
88633 - Positive stranded ssRNA viruses
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,52540,47819
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
47819 - HRDC-like | 0 | Direct |
49899,48726,49265
49899 - Concanavalin A-like lectins/glucanases
48726 - Immunoglobulin
49265 - Fibronectin type III | 0 | Direct |
47769,47769,52200
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain
52200 - Toll/Interleukin receptor TIR domain | 0 | Direct |
57756,57756,51283
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains
51283 - dUTPase-like | 0 | Direct |
52540,49899,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
49899 - Concanavalin A-like lectins/glucanases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
56487,57424,57424
56487 - SRCR-like
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
54211,54211,54637
54211 - Ribosomal protein S5 domain 2-like
54211 - Ribosomal protein S5 domain 2-like
54637 - Thioesterase/thiol ester dehydrase-isomerase | 0 | Direct |
50494,52540,56672
50494 - Trypsin-like serine proteases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0 | Direct |
55486,57440,57440
55486 - Metalloproteases ("zincins"), catalytic domain
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
69065,69065,54768
69065 - RNase III domain-like
69065 - RNase III domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
51283,50630,56672
51283 - dUTPase-like
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | Direct |
52540,54980,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
54980 - EF-G C-terminal domain-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
49854,49854,57424
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module | 0 | Direct |
52200,52540,46785
52200 - Toll/Interleukin receptor TIR domain
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
56672,53098,50122
56672 - DNA/RNA polymerases
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
57492,74650,51445
57492 - Trefoil
74650 - Galactose mutarotase-like
51445 - (Trans)glycosidases | 0 | Direct |
57440,57440,57440
57440 - Kringle-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
53300,100939,68906
53300 - vWA-like
100939 - SPOC domain-like
68906 - SAP domain | 0 | Direct |
57424,57424,57424
57424 - LDL receptor-like module
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
52540,56712,51294
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
49854,57196,49854
49854 - Spermadhesin, CUB domain
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
57630,57196,50494
57630 - GLA-domain
57196 - EGF/Laminin
50494 - Trypsin-like serine proteases | 0 | Direct |
81296,51445,54556
81296 - E set domains
51445 - (Trans)glycosidases
54556 - Chitinase insertion domain | 0 | Direct |
56672,46919,53098
56672 - DNA/RNA polymerases
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
52540,52540,46785
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
50249,52540,52540
50249 - Nucleic acid-binding proteins
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50692,54585,52540
50692 - ADC-like
54585 - Cdc48 domain 2-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50199,50199,50199
50199 - Staphylococcal nuclease
50199 - Staphylococcal nuclease
50199 - Staphylococcal nuclease | 0 | Direct |
55486,58091,49899
55486 - Metalloproteases ("zincins"), catalytic domain
58091 - Clostridium neurotoxins, "coiled-coil" domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
48371,47769,47769
48371 - ARM repeat
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
57424,56487,50494
57424 - LDL receptor-like module
56487 - SRCR-like
50494 - Trypsin-like serine proteases | 0 | Direct |
49785,49303,51445
49785 - Galactose-binding domain-like
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases | 0 | Direct |
49303,51445,49303
49303 - beta-Galactosidase/glucuronidase domain
51445 - (Trans)glycosidases
49303 - beta-Galactosidase/glucuronidase domain | 0 | Direct |
57535,53300,50494
57535 - Complement control module/SCR domain
53300 - vWA-like
50494 - Trypsin-like serine proteases | 0 | Direct |
53098,51283,46919
53098 - Ribonuclease H-like
51283 - dUTPase-like
46919 - N-terminal Zn binding domain of HIV integrase | 0 | Direct |
81761,53474,49785
81761 - X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
53474 - alpha/beta-Hydrolases
49785 - Galactose-binding domain-like | 0 | Direct |
49785,51445,49344
49785 - Galactose-binding domain-like
51445 - (Trans)glycosidases
49344 - CBD9-like | 0 | Direct |
51445,51011,50370
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
50370 - Ricin B-like lectins | 0 | Direct |
47353,57756,57756
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
100895,56487,57424
100895 - Kazal-type serine protease inhibitors
56487 - SRCR-like
57424 - LDL receptor-like module | 0 | Direct |
88633,88633,88633
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
82671,49854,49854
82671 - SEA domain
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
49854,57424,57424
49854 - Spermadhesin, CUB domain
57424 - LDL receptor-like module
57424 - LDL receptor-like module | 0 | Direct |
50199,50199,63748
50199 - Staphylococcal nuclease
50199 - Staphylococcal nuclease
63748 - Tudor/PWWP/MBT | 0 | Direct |
48024,52540,51294
48024 - N-terminal domain of DnaB helicase
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
55545,51445,140657
55545 - beta-N-acetylhexosaminidase-like domain
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like | 0 | Direct |
53098,46919,53098
53098 - Ribonuclease H-like
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like | 0 | Direct |
52743,49785,57184
52743 - Subtilisin-like
49785 - Galactose-binding domain-like
57184 - Growth factor receptor domain | 0 | Direct |
56024,56024,56024
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease
56024 - Phospholipase D/nuclease | 0 | Direct |
50494,50156,50156
50494 - Trypsin-like serine proteases
50156 - PDZ domain-like
50156 - PDZ domain-like | 0 | Direct |
52799,56091,50249
52799 - (Phosphotyrosine protein) phosphatases II
56091 - DNA ligase/mRNA capping enzyme, catalytic domain
50249 - Nucleic acid-binding proteins | 0 | Direct |
50249,47781,46929
50249 - Nucleic acid-binding proteins
47781 - RuvA domain 2-like
46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
54160,52540,52540
54160 - Chromo domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57414,57440,57440
57414 - Hairpin loop containing domain-like
57440 - Kringle-like
57440 - Kringle-like | 0 | Direct |
57630,57184,50494
57630 - GLA-domain
57184 - Growth factor receptor domain
50494 - Trypsin-like serine proteases | 0 | Direct |
55781,55781,109604
55781 - GAF domain-like
55781 - GAF domain-like
109604 - HD-domain/PDEase-like | 0 | Direct |
47943,47353,57756
47943 - Retrovirus capsid protein, N-terminal core domain
47353 - Retrovirus capsid dimerization domain-like
57756 - Retrovirus zinc finger-like domains | 0 | Direct |
82671,57424,49854
82671 - SEA domain
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain | 0 | Direct |
55550,50044,51695
55550 - SH2 domain
50044 - SH3-domain
51695 - PLC-like phosphodiesterases | 0 | Direct |
47986,47986,52129
47986 - DEATH domain
47986 - DEATH domain
52129 - Caspase-like | 0 | Direct |
81324,52799,49562
81324 - Voltage-gated potassium channels
52799 - (Phosphotyrosine protein) phosphatases II
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
46938,52087,52799
46938 - CRAL/TRIO N-terminal domain
52087 - CRAL/TRIO domain
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
55486,49899,49599
55486 - Metalloproteases ("zincins"), catalytic domain
49899 - Concanavalin A-like lectins/glucanases
49599 - TRAF domain-like | 0 | Direct |
50729,47473,51695
50729 - PH domain-like
47473 - EF-hand
51695 - PLC-like phosphodiesterases | 0 | Direct |
57756,50630,56672
57756 - Retrovirus zinc finger-like domains
50630 - Acid proteases
56672 - DNA/RNA polymerases | 0 | Direct |
46785,158702,52540
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
158702,52540,52540
158702 - Sec63 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46919,53098,50122
46919 - N-terminal Zn binding domain of HIV integrase
53098 - Ribonuclease H-like
50122 - DNA-binding domain of retroviral integrase | 0 | Direct |
57440,57440,50494
57440 - Kringle-like
57440 - Kringle-like
50494 - Trypsin-like serine proteases | 0 | Direct |
52540,89043,50494
52540 - P-loop containing nucleoside triphosphate hydrolases
89043 - Soluble domain of poliovirus core protein 3a
50494 - Trypsin-like serine proteases | 0 | Direct |
51445,140657,49785
51445 - (Trans)glycosidases
140657 - Hyaluronidase post-catalytic domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
141734,101386,53720
141734 - HisI-like
101386 - all-alpha NTP pyrophosphatases
53720 - ALDH-like | 0 | Direct |
52540,50447,54980
52540 - P-loop containing nucleoside triphosphate hydrolases
50447 - Translation proteins
54980 - EF-G C-terminal domain-like | 0 | Direct |
55781,55781,55781
55781 - GAF domain-like
55781 - GAF domain-like
55781 - GAF domain-like | 0 | Direct |
52540,46785,158702
52540 - P-loop containing nucleoside triphosphate hydrolases
46785 - "Winged helix" DNA-binding domain
158702 - Sec63 N-terminal domain-like | 0 | Direct |
117100,49785,49785
117100 - Beta-galactosidase LacA, domain 3
49785 - Galactose-binding domain-like
49785 - Galactose-binding domain-like | 0 | Direct |
54001,88633,88633
54001 - Cysteine proteinases
88633 - Positive stranded ssRNA viruses
88633 - Positive stranded ssRNA viruses | 0 | Direct |
63411,63411,63411
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase
63411 - LuxS/MPP-like metallohydrolase | 0 | Direct |
51011,51445,51011
51011 - Glycosyl hydrolase domain
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0 | Direct |
52540,52540,142877
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
142877 - EndoU-like | 0 | Direct |
51445,49344,49344
51445 - (Trans)glycosidases
49344 - CBD9-like
49344 - CBD9-like | 0 | Direct |
140367,143076,101816
140367 - Coronavirus NSP7-like
143076 - Coronavirus NSP8-like
101816 - Replicase NSP9 | 0 | Direct |
52540,52540,56712
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
57424,49854,49899
57424 - LDL receptor-like module
49854 - Spermadhesin, CUB domain
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53098,47819,47819
53098 - Ribonuclease H-like
47819 - HRDC-like
47819 - HRDC-like | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
54897,52743,49785
54897 - Protease propeptides/inhibitors
52743 - Subtilisin-like
49785 - Galactose-binding domain-like | 0 | Direct |
88713,88688,74650
88713 - Glycoside hydrolase/deacetylase
88688 - Families 57/38 glycoside transferase middle domain
74650 - Galactose mutarotase-like | 0.00000000002664 | Direct |
52283,51735,52283
52283 - Formate/glycerate dehydrogenase catalytic domain-like
51735 - NAD(P)-binding Rossmann-fold domains
52283 - Formate/glycerate dehydrogenase catalytic domain-like | 0.0000000002262 | Direct |
52540,52540,56672
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
56672 - DNA/RNA polymerases | 0.00000007213 | Direct |
48726,49265,49265
48726 - Immunoglobulin
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.000001155 | Direct |
52335,51556,51338
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases
51338 - Composite domain of metallo-dependent hydrolases | 0.000003267 | Direct |
51445,51011,49452
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain
49452 - Starch-binding domain-like | 0.00001607 | Direct |
51735,47336,53474
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like
53474 - alpha/beta-Hydrolases | 0.00007897 | Direct |
56059,52335,51556
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like
51556 - Metallo-dependent hydrolases | 0.00009526 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0.0004372 | Direct |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.001905 | Inherited |
52540,51294,55608
52540 - P-loop containing nucleoside triphosphate hydrolases
51294 - Hedgehog/intein (Hint) domain
55608 - Homing endonucleases | 0.002314 | Inherited |
52317,52440,56059
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0.002807 | Inherited |
52021,52317,52440
52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
52317 - Class I glutamine amidotransferase-like
52440 - PreATP-grasp domain | 0.002807 | Inherited |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.008046 | Inherited |
81296,51445,51011
81296 - E set domains
51445 - (Trans)glycosidases
51011 - Glycosyl hydrolase domain | 0.03646 | Inherited |
109604,81301,81271
109604 - HD-domain/PDEase-like
81301 - Nucleotidyltransferase
81271 - TGS-like | 0.05535 | Inherited |
50129,51735,51735
50129 - GroES-like
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains | 0.1182 | Inherited |
51735,51735,47336
51735 - NAD(P)-binding Rossmann-fold domains
51735 - NAD(P)-binding Rossmann-fold domains
47336 - ACP-like | 0.7206 | Inherited |
48108,52440,56059
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 1 | Inherited |
52440,56059,48108
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain | 1 | Inherited |
52518,52467,52518
52518 - Thiamin diphosphate-binding fold (THDP-binding)
52467 - DHS-like NAD/FAD-binding domain
52518 - Thiamin diphosphate-binding fold (THDP-binding) | 1 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 1 | Inherited |
52440,56059,52335
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
52335 - Methylglyoxal synthase-like | 1 | Inherited |
56059,48108,52440
56059 - Glutathione synthetase ATP-binding domain-like
48108 - Carbamoyl phosphate synthetase, large subunit connection domain
52440 - PreATP-grasp domain | 1 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
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heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
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