Enzyme Commission (EC): Endoribonucleases producing 5'-phosphomonoesters

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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:

Disease Ontology (DO) Ontology (DO)
DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
Human Phenotype (HP) Ontology (HP)
HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
Mouse Phenotype (MP) Ontology (MP)
MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
Worm Phenotype (WP) Ontology (WP)
WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
Yeast Phenotype (YP) Ontology (YP)
Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
Fly Phenotype (FP) Ontology (FP)
FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
Fly Anatomy (FA) Ontology (FA)
FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
Zebrafish Anatomy (ZA) Ontology (ZA)
ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
Xenopus Anatomy (XA) Ontology (XA)
XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
Arabidopsis Plant Ontology (AP) Ontology (AP)
As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
Enzyme Commission (EC) Ontology (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
DrugBank ATC (DB) Ontology (DB)
In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
UniProtKB KeyWords (KW) Ontology (KW)
Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
UniProtKB UniPathway (UP) Ontology (UP)
UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.

Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).

Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)

+ + + 3: root [root] <7>

+ + 2: Hydrolases [3] <13> (396|669) (395|421|209)

+ 1: Acting on ester bonds [3.1] <23> (157|226) (157|126|55)

0: Endoribonucleases producing 5'-phosphomonoesters [3.1.26] <15> (24|29) (24|21|20)

- 1: Argonaute-2 [3.1.26.n2] (1|1) (1|1|0)

- 1: Physarum polycephalum ribonuclease [3.1.26.1] (0|0) (0|0|0)

- 1: Retroviral ribonuclease H [3.1.26.13] (10|11) (10|11|11)

- 1: Ribonuclease (poly-(U)-specific) [3.1.26.9] (0|0) (0|0|0)

- 1: Ribonuclease E [3.1.26.12] (1|1) (1|0|0)

- 1: Ribonuclease H [3.1.26.4] (3|9) (3|7|8)

- 1: Ribonuclease III [3.1.26.3] (2|2) (2|2|1)

- 1: Ribonuclease IV [3.1.26.6] (0|0) (0|0|0)

- 1: Ribonuclease IX [3.1.26.10] (0|0) (0|0|0)

- 1: Ribonuclease M5 [3.1.26.8] (1|1) (1|0|0)

- 1: Ribonuclease P [3.1.26.5] (7|5) (7|0|0)

- 1: Ribonuclease P4 [3.1.26.7] (0|0) (0|0|0)

- 1: Ribonuclease Z [3.1.26.11] (1|1) (1|0|0)

- 1: Ribonuclease alpha [3.1.26.2] (0|0) (0|0|0)

- 1: Transferred entry: 3.1.26.12 [3.1.26.n1] (0|0) (0|0|0)

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Superfamily

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SCOP term	FDR (all)	Annotation (direct or inherited)
Rof/RNase P subunit-like	0	Direct
Retrovirus capsid dimerization domain-like	0	Direct
RNase III domain-like	0	Direct
Rnp2-like	0	Direct
Retroviral matrix proteins	0	Direct
Ribonuclease H-like	0	Direct
AlbA-like	0	Direct
Acid proteases	0	Direct
DNA-binding domain of retroviral integrase	0	Direct
L9 N-domain-like	0	Direct
PAZ domain	0	Direct
Ribosomal protein S5 domain 2-like	0	Direct
dsRNA-binding domain-like	0	Direct
Retrovirus zinc finger-like domains	0	Direct
Toprim domain	0	Direct
N-terminal Zn binding domain of HIV integrase	0	Direct
DNA/RNA polymerases	0	Direct
Retrovirus capsid protein, N-terminal core domain	0	Direct
Metallo-hydrolase/oxidoreductase	0	Direct
PHP domain-like	0.0000000004184	Direct
PIN domain-like	0.00000002373	Direct
L30e-like	0.0001591	Direct
dUTPase-like	0.000817	Direct
Nucleic acid-binding proteins	1	Inherited

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Family

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SCOP term	FDR (all)	Annotation (direct or inherited)
HTLV-II matrix protein	0	Direct
Retrovirus capsid protein, N-terminal core domain	0	Direct
Retrovirus zinc finger-like domains	0	Direct
RNase P subunit p30	0	Direct
Ribonuclease H	0	Direct
RNase III catalytic domain-like	0	Direct
Retrovirus capsid protein C-terminal domain	0	Direct
L30e/L7ae ribosomal proteins	0	Direct
RNase P subunit p29-like	0	Direct
Immunodeficiency virus matrix proteins	0	Direct
RNase Z-like	0	Direct
GAG polyprotein M-domain	0	Direct
Retroviral integrase, catalytic domain	0	Direct
MMLV matrix protein-like	0	Direct
RNase P protein	0	Direct
Double-stranded RNA-binding domain (dsRBD)	0	Direct
N-terminal Zn binding domain of HIV integrase	0	Direct
Reverse transcriptase	0	Direct
PAZ domain	0	Direct
Rpp14/Pop5-like	0	Direct
Toprim domain	0	Direct
DNA-binding domain of retroviral integrase	0	Direct
Retroviral protease (retropepsin)	0	Direct
N-terminal domain of RNase HI	0	Direct
Mason-Pfizer monkey virus matrix protein	0.0000000000001219	Direct
DNA polymerase I	0.000001886	Direct
dUTPase-like	0.001033	Inherited
DnaQ-like 3'-5' exonuclease	0.9516	Inherited
Cold shock DNA-binding domain-like	1	Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
N-terminal Zn binding domain of HIV integrase	0	Direct
RNase III domain-like	0	Direct
Retrovirus capsid dimerization domain-like	0	Direct
Ribonuclease H-like	0	Direct
PAZ domain	0	Direct
Toprim domain	0	Direct
Retrovirus capsid protein, N-terminal core domain	0	Direct
L9 N-domain-like	0	Direct
Acid proteases	0	Direct
Rof/RNase P subunit-like	0	Direct
Retrovirus zinc finger-like domains	0	Direct
dsRNA-binding domain-like	0	Direct
Metallo-hydrolase/oxidoreductase	0	Direct
AlbA-like	0	Direct
Retroviral matrix proteins	0	Direct
DNA-binding domain of retroviral integrase	0	Direct
DNA/RNA polymerases	0	Direct
Ribosomal protein S5 domain 2-like	0	Direct
Rnp2-like	0	Direct
PHP domain-like	0.0000000003095	Direct
PIN domain-like	0.00000001799	Direct
L30e-like	0.0001289	Direct
dUTPase-like	0.0006721	Direct
Nucleic acid-binding proteins	1	Inherited

(show details)

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
69065,54768 69065 - RNase III domain-like 54768 - dsRNA-binding domain-like	0	Direct
53098,50122 53098 - Ribonuclease H-like 50122 - DNA-binding domain of retroviral integrase	0	Direct
53098,53098 53098 - Ribonuclease H-like 53098 - Ribonuclease H-like	0	Direct
47836,47943 47836 - Retroviral matrix proteins 47943 - Retrovirus capsid protein, N-terminal core domain	0	Direct
101690,53098 101690 - PAZ domain 53098 - Ribonuclease H-like	0	Direct
47353,57756 47353 - Retrovirus capsid dimerization domain-like 57756 - Retrovirus zinc finger-like domains	0	Direct
56672,46919 56672 - DNA/RNA polymerases 46919 - N-terminal Zn binding domain of HIV integrase	0	Direct
55658,53098 55658 - L9 N-domain-like 53098 - Ribonuclease H-like	0	Direct
69065,69065 69065 - RNase III domain-like 69065 - RNase III domain-like	0	Direct
46919,53098 46919 - N-terminal Zn binding domain of HIV integrase 53098 - Ribonuclease H-like	0	Direct
53098,51283 53098 - Ribonuclease H-like 51283 - dUTPase-like	0	Direct
53098,46919 53098 - Ribonuclease H-like 46919 - N-terminal Zn binding domain of HIV integrase	0	Direct
57756,50630 57756 - Retrovirus zinc finger-like domains 50630 - Acid proteases	0	Direct
51283,46919 51283 - dUTPase-like 46919 - N-terminal Zn binding domain of HIV integrase	0	Direct
50630,56672 50630 - Acid proteases 56672 - DNA/RNA polymerases	0	Direct
56672,53098 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like	0	Direct
47943,47353 47943 - Retrovirus capsid protein, N-terminal core domain 47353 - Retrovirus capsid dimerization domain-like	0	Direct
57756,51283 57756 - Retrovirus zinc finger-like domains 51283 - dUTPase-like	0.00000000000008067	Direct
51283,50630 51283 - dUTPase-like 50630 - Acid proteases	0.00000000000008067	Direct
57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains	0.0000000191	Direct
53098,56672 53098 - Ribonuclease H-like 56672 - DNA/RNA polymerases	0.0000001078	Direct

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Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
51283,46919,53098 51283 - dUTPase-like 46919 - N-terminal Zn binding domain of HIV integrase 53098 - Ribonuclease H-like	0	Direct
50630,56672,53098 50630 - Acid proteases 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like	0	Direct
50630,56672,46919 50630 - Acid proteases 56672 - DNA/RNA polymerases 46919 - N-terminal Zn binding domain of HIV integrase	0	Direct
56672,53098,51283 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like 51283 - dUTPase-like	0	Direct
47836,47943,47353 47836 - Retroviral matrix proteins 47943 - Retrovirus capsid protein, N-terminal core domain 47353 - Retrovirus capsid dimerization domain-like	0	Direct
56672,53098,46919 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like 46919 - N-terminal Zn binding domain of HIV integrase	0	Direct
47353,57756,50630 47353 - Retrovirus capsid dimerization domain-like 57756 - Retrovirus zinc finger-like domains 50630 - Acid proteases	0	Direct
56672,53098,53098 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like 53098 - Ribonuclease H-like	0	Direct
69065,69065,54768 69065 - RNase III domain-like 69065 - RNase III domain-like 54768 - dsRNA-binding domain-like	0	Direct
51283,50630,56672 51283 - dUTPase-like 50630 - Acid proteases 56672 - DNA/RNA polymerases	0	Direct
56672,53098,50122 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like 50122 - DNA-binding domain of retroviral integrase	0	Direct
56672,46919,53098 56672 - DNA/RNA polymerases 46919 - N-terminal Zn binding domain of HIV integrase 53098 - Ribonuclease H-like	0	Direct
53098,51283,46919 53098 - Ribonuclease H-like 51283 - dUTPase-like 46919 - N-terminal Zn binding domain of HIV integrase	0	Direct
53098,46919,53098 53098 - Ribonuclease H-like 46919 - N-terminal Zn binding domain of HIV integrase 53098 - Ribonuclease H-like	0	Direct
47943,47353,57756 47943 - Retrovirus capsid protein, N-terminal core domain 47353 - Retrovirus capsid dimerization domain-like 57756 - Retrovirus zinc finger-like domains	0	Direct
57756,50630,56672 57756 - Retrovirus zinc finger-like domains 50630 - Acid proteases 56672 - DNA/RNA polymerases	0	Direct
46919,53098,50122 46919 - N-terminal Zn binding domain of HIV integrase 53098 - Ribonuclease H-like 50122 - DNA-binding domain of retroviral integrase	0	Direct
57756,51283,50630 57756 - Retrovirus zinc finger-like domains 51283 - dUTPase-like 50630 - Acid proteases	0.00000000000008067	Direct
57756,57756,51283 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains 51283 - dUTPase-like	0.000000000585	Direct
47353,57756,57756 47353 - Retrovirus capsid dimerization domain-like 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains	0.000000000585	Direct

Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term

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Enzyme Commission (EC): Endoribonucleases producing 5'-phosphomonoesters

Superfamily

Family

Supra-domain (including individual superfamily)