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  Home > Phenotype Ontology > Phosphoric monoester hydrolases

Enzyme Commission (EC): Phosphoric monoester hydrolases

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Hydrolases [3] <13>(396|669) (395|421|209)
+ 1:   Acting on ester bonds [3.1] <23>(157|226) (157|126|55)
0:   Phosphoric monoester hydrolases [3.1.3] <112>(60|78) (60|45|12)
- 1:   2,3-bisphosphoglycerate 3-phosphatase [3.1.3.80](1|1) (1|0|0)
- 1:   2-carboxy-D-arabinitol-1-phosphatase [3.1.3.63](0|0) (0|0|0)
- 1:   2-deoxyglucose-6-phosphatase [3.1.3.68](0|0) (0|0|0)
- 1:   2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [3.1.3.87](1|1) (1|0|0)
- 1:   2-lysophosphatidate phosphatase [3.1.3.106](0|0) (0|0|0)
- 1:   2-phosphosulfolactate phosphatase [3.1.3.71](1|1) (1|0|0)
- 1:   3'(2'),5'-bisphosphate nucleotidase [3.1.3.7](2|1) (2|0|0)
- 1:   3',5'-nucleoside bisphosphate phosphatase [3.1.3.97](1|1) (1|0|0)
- 1:   3'-nucleotidase [3.1.3.6](2|3) (2|1|0)
- 1:   3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphatase [3.1.3.103](0|0) (0|0|0)
- 1:   3-deoxy-manno-octulosonate-8-phosphatase [3.1.3.45](1|1) (1|0|0)
- 1:   3-phosphoglycerate phosphatase [3.1.3.38](0|0) (0|0|0)
- 1:   3-phytase [3.1.3.8](2|2) (2|0|0)
- 1:   4-nitrophenylphosphatase [3.1.3.41](0|0) (0|0|0)
- 1:   4-phytase [3.1.3.26](0|0) (0|0|0)
- 1:   5''-phosphoribostamycin phosphatase [3.1.3.88](0|0) (0|0|0)
- 1:   5'-deoxynucleotidase [3.1.3.89](1|1) (1|0|0)
- 1:   5'-nucleotidase [3.1.3.5](2|5) (2|1|0)
- 1:   5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [3.1.3.104](1|1) (1|0|0)
- 1:   5-phytase [3.1.3.72](0|0) (0|0|0)
- 1:   7-methylguanosine nucleotidase [3.1.3.91](1|1) (1|0|0)
- 1:   ADP-phosphoglycerate phosphatase [3.1.3.28](0|0) (0|0|0)
- 1:   ADP-ribose 1''-phosphate phosphatase [3.1.3.84](4|1) (4|1|0)
- 1:   Acid phosphatase [3.1.3.2](4|6) (4|1|0)
- 1:   Acireductone synthase [3.1.3.77](2|2) (2|1|0)
- 1:   Adenosylcobalamin/alpha-ribazole phosphatase [3.1.3.73](1|0) (1|0|0)
- 1:   Alkaline phosphatase [3.1.3.1](2|2) (2|0|0)
- 1:   Alkylacetylglycerophosphatase [3.1.3.59](0|0) (0|0|0)
- 1:   Caldesmon-phosphatase [3.1.3.55](0|0) (0|0|0)
- 1:   D-galactose 1-phosphate phosphatase [3.1.3.94](1|1) (1|0|0)
- 1:   D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase [3.1.3.83](1|1) (1|0|0)
- 1:   D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase [3.1.3.82](1|1) (1|0|0)
- 1:   Deleted entry [3.1.3.61](0|0) (0|0|0)
- 1:   Deleted entry [3.1.3.13](0|0) (0|0|0)
- 1:   Deoxynucleotide 3'-phosphatase [3.1.3.34](0|0) (0|0|0)
- 1:   Diacylglycerol diphosphate phosphatase [3.1.3.81](1|0) (1|0|0)
- 1:   Dolichyl-phosphatase [3.1.3.51](0|0) (0|0|0)
- 1:   FMN hydrolase [3.1.3.102](0|0) (0|0|0)
- 1:   Fructose-2,6-bisphosphate 2-phosphatase [3.1.3.46](2|3) (2|1|0)
- 1:   Fructose-2,6-bisphosphate 6-phosphatase [3.1.3.54](0|0) (0|0|0)
- 1:   Fructose-bisphosphatase [3.1.3.11](2|3) (2|1|0)
- 1:   Glucose-1-phosphatase [3.1.3.10](1|1) (1|0|0)
- 1:   Glucose-6-phosphatase [3.1.3.9](1|0) (1|0|0)
- 1:   Glucosyl-3-phosphoglycerate phosphatase [3.1.3.85](0|0) (0|0|0)
- 1:   Glucosylglycerol 3-phosphatase [3.1.3.69](0|0) (0|0|0)
- 1:   Glycerol-1-phosphatase [3.1.3.21](1|1) (1|0|0)
- 1:   Glycerol-2-phosphatase [3.1.3.19](0|0) (0|0|0)
- 1:   Guanidinodeoxy-scyllo-inositol-4-phosphatase [3.1.3.40](0|0) (0|0|0)
- 1:   Histidinol-phosphatase [3.1.3.15](3|3) (3|2|1)
- 1:   IMP-specific 5'-nucleotidase [3.1.3.99](1|0) (1|0|0)
- 1:   Inositol-1,4-bisphosphate 1-phosphatase [3.1.3.57](1|1) (1|0|0)
- 1:   Inositol-phosphate phosphatase [3.1.3.25](1|1) (1|0|0)
- 1:   Inositol-polyphosphate 5-phosphatase [3.1.3.56](3|3) (3|0|0)
- 1:   Kanosamine-6-phosphate phosphatase [3.1.3.92](0|0) (0|0|0)
- 1:   L-galactose 1-phosphate phosphatase [3.1.3.93](0|0) (0|0|0)
- 1:   Lipid-phosphate phosphatase [3.1.3.76](1|2) (1|1|0)
- 1:   Maltose 6'-phosphate phosphatase [3.1.3.90](0|0) (0|0|0)
- 1:   Mannitol-1-phosphatase [3.1.3.22](0|0) (0|0|0)
- 1:   Mannosyl-3-phosphoglycerate phosphatase [3.1.3.70](1|1) (1|0|0)
- 1:   Mannosylfructose-phosphate phosphatase [3.1.3.79](0|0) (0|0|0)
- 1:   Methylphosphothioglycerate phosphatase [3.1.3.14](0|0) (0|0|0)
- 1:   Multiple inositol-polyphosphate phosphatase [3.1.3.62](1|1) (1|0|0)
- 1:   N-acetyl-D-muramate 6-phosphate phosphatase [3.1.3.105](0|0) (0|0|0)
- 1:   N-acylneuraminate-9-phosphatase [3.1.3.29](0|1) (0|0|0)
- 1:   Nucleotidase [3.1.3.31](0|0) (0|0|0)
- 1:   Phosphatidate phosphatase [3.1.3.4](1|0) (1|0|0)
- 1:   Phosphatidylglycerophosphatase [3.1.3.27](1|0) (1|0|0)
- 1:   Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase [3.1.3.67](2|2) (2|1|0)
- 1:   Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase [3.1.3.86](4|4) (4|1|0)
- 1:   Phosphatidylinositol-3,4-bisphosphate 4-phosphatase [3.1.3.66](1|0) (1|0|0)
- 1:   Phosphatidylinositol-3,5-bisphosphate 3-phosphatase [3.1.3.95](3|3) (3|1|0)
- 1:   Phosphatidylinositol-3-phosphatase [3.1.3.64](3|3) (3|1|0)
- 1:   Phosphatidylinositol-4,5-bisphosphate 4-phosphatase [3.1.3.78](0|0) (0|0|0)
- 1:   Phosphoenolpyruvate phosphatase [3.1.3.60](0|0) (0|0|0)
- 1:   Phosphoethanolamine/phosphocholine phosphatase [3.1.3.75](0|0) (0|0|0)
- 1:   Phosphoglycerate phosphatase [3.1.3.20](0|0) (0|0|0)
- 1:   Phosphoglycolate phosphatase [3.1.3.18](1|2) (1|0|0)
- 1:   Phosphoinositide 5-phosphatase [3.1.3.36](4|4) (4|2|0)
- 1:   Phosphoserine phosphatase [3.1.3.3](2|2) (2|0|0)
- 1:   Polynucleotide 3'-phosphatase [3.1.3.32](2|2) (2|1|0)
- 1:   Polynucleotide 5'-phosphatase [3.1.3.33](6|4) (6|4|1)
- 1:   Protein-serine/threonine phosphatase [3.1.3.16](11|10) (11|8|0)
- 1:   Protein-tyrosine-phosphatase [3.1.3.48](21|23) (21|19|9)
- 1:   Pseudouridine 5'-phosphatase [3.1.3.96](0|1) (0|0|0)
- 1:   Pyridoxal phosphatase [3.1.3.74](1|2) (1|0|0)
- 1:   Sedoheptulose-bisphosphatase [3.1.3.37](1|1) (1|0|0)
- 1:   Sorbitol-6-phosphatase [3.1.3.50](0|0) (0|0|0)
- 1:   Streptomycin-6-phosphatase [3.1.3.39](0|0) (0|0|0)
- 1:   Sucrose-phosphate phosphatase [3.1.3.24](2|1) (2|1|0)
- 1:   Sugar-phosphatase [3.1.3.23](1|1) (1|0|0)
- 1:   Sugar-terminal-phosphatase [3.1.3.58](0|0) (0|0|0)
- 1:   Thiamine phosphate phosphatase [3.1.3.100](0|0) (0|0|0)
- 1:   Thymidylate 5'-phosphatase [3.1.3.35](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.3.31 [3.1.3.30](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.3.64 [3.1.3.65](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.3.78 [3.1.3.n3](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.3.84 [3.1.3.n2](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.3.86 [3.1.3.n1](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.3.87 [3.1.3.n4](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.3.93 [3.1.3.n5](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.3.96 [3.1.3.n6](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.1.68 [3.1.3.98](0|0) (0|0|0)
- 1:   Trehalose-phosphatase [3.1.3.12](2|2) (2|2|0)
- 1:   Validoxylamine A 7'-phosphate phosphatase [3.1.3.101](0|0) (0|0|0)
- 1:   [Acetyl-CoA carboxylase]-phosphatase [3.1.3.44](0|0) (0|0|0)
- 1:   [Glycogen-synthase-D] phosphatase [3.1.3.42](0|0) (0|0|0)
- 1:   [Hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase [3.1.3.47](0|0) (0|0|0)
- 1:   [Myosin-light-chain] phosphatase [3.1.3.53](0|0) (0|0|0)
- 1:   [Phosphorylase] phosphatase [3.1.3.17](0|0) (0|0|0)
- 1:   [Pyruvate dehydrogenase (acetyl-transferring)]-phosphatase [3.1.3.43](1|1) (1|0|0)
- 1:   [Pyruvate kinase]-phosphatase [3.1.3.49](0|0) (0|0|0)
- 1:   phosphatase [3.1.3.52](0|0) (0|0|0)

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Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Bacterial GAP domain0Direct
PP2C-like0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
ComB-like0Direct
(Phosphotyrosine protein) phosphatases II0Direct
Voltage-gated potassium channels0Direct
Purple acid phosphatase, N-terminal domain0Direct
CRAL/TRIO N-terminal domain0Direct
Carbohydrate phosphatase0Direct
HAD-like0Direct
Phosphotyrosine protein phosphatases I0Direct
Fibronectin type III0Direct
SurE-like0Direct
CYTH-like phosphatases0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0Direct
Phosphoglycerate mutase-like0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
Metallo-dependent phosphatases0Direct
Rhodanese/Cell cycle control phosphatase0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
Immunoglobulin2.574e-16Direct
Second domain of FERM0.0000000000000552Direct
DEK C-terminal domain0.0000000000001386Direct
Macro domain-like0.00000000004116Direct
Ubiquitin-like0.000000002276Direct
GTPase activation domain, GAP0.00000000374Direct
NTF2-like0.000000009306Direct
SH2 domain0.000001014Direct
Chaperone J-domain0.000002091Direct
PH domain-like0.000007383Direct
Kelch motif0.00001753Direct
CRAL/TRIO domain0.00002636Direct
Non-globular alpha+beta subunits of globular proteins0.0003259Direct
FYVE/PHD zinc finger0.0005347Direct
PDZ domain-like0.0008281Direct
TPR-like0.001105Inherited
Carbonic anhydrase0.001622Inherited
DNase I-like0.00168Inherited
SAM/Pointed domain0.003047Inherited
AraD/HMP-PK domain-like0.003544Inherited
Starch-binding domain-like0.0128Inherited
RNA-binding domain, RBD0.0197Inherited
DHH phosphoesterases0.0284Inherited
Thermostable phytase (3-phytase)0.03613Inherited
Alkaline phosphatase-like0.13Inherited
PHP domain-like0.371Inherited
Concanavalin A-like lectins/glucanases0.3943Inherited
L domain-like0.7469Inherited
EF-hand1Inherited
alpha/beta-Hydrolases1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
ACT-like1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
HD-domain/PDEase-like1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Ribosomal protein S5 domain 2-like1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
Periplasmic binding protein-like II1Inherited
DNA/RNA polymerases1Inherited

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Alkaline phosphatase0Direct
Cell cycle control phosphatase, catalytic domain0Direct
YihX-like0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0Direct
MtnX-like0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
CRAL/TRIO N-terminal domain0Direct
Class B acid phosphatase, AphA0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Phosphoserine phosphatase0Direct
Dual specificity phosphatase-like0Direct
Predicted hydrolases Cof0Direct
Purple acid phosphatase-like0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
GRAM domain0Direct
NagD-like0Direct
Fibronectin type III0Direct
mRNA triphosphatase CET10Direct
Histidine acid phosphatase0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain0Direct
I set domains0Direct
Enolase-phosphatase E10Direct
Purple acid phosphatase, N-terminal domain0Direct
GlpX-like bacterial fructose-1,6-bisphosphatase0Direct
Trehalose-phosphatase0Direct
Third domain of FERM0Direct
Histidinol phosphatase-like0Direct
beta-Phosphoglucomutase-like0Direct
SurE-like0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0Direct
PP2C-like0Direct
Myotubularin-like phosphatases0Direct
Low-molecular-weight phosphotyrosine protein phosphatases0Direct
Protein serine/threonine phosphatase0Direct
Type 2 phosphatidic acid phosphatase, PAP20Direct
Pyrimidine 5'-nucleotidase (UMPH-1)0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0Direct
ComB-like0Direct
Bacterial GAP domain0Direct
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0Direct
Magnesium-dependent phosphatase-1, Mdp10Direct
CRAL/TRIO domain0Direct
Thermostable phytase (3-phytase)0Direct
5' nucleotidase-like0Direct
Imidazole glycerol phosphate dehydratase0Direct
Virulence effector SptP domain0Direct
Higher-molecular-weight phosphotyrosine protein phosphatases0Direct
NLI interacting factor-like phosphatase0Direct
MAM domain0.00000000000001602Direct
Second domain of FERM0.00000000000002439Direct
First domain of FERM0.00000000000005878Direct
phosphatase domain of polynucleotide kinase0.0000000000006273Direct
Probable phosphatase YrbI0.0000000000589Direct
DEK C-terminal domain0.0000000002415Direct
BCR-homology GTPase activation domain (BH-domain)0.000000002749Direct
PDZ domain0.000000003813Direct
Ubiquitin-related0.000000004096Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.00000001146Direct
Macro domain0.00000001159Direct
Leucine rich effector protein YopM0.00000002818Direct
SH2 domain0.0000007989Direct
Chaperone J-domain0.000001616Direct
HD domain0.000002443Direct
mRNA capping enzyme0.000003269Direct
Epoxide hydrolase0.00004657Direct
Tetratricopeptide repeat (TPR)0.00005298Direct
mRNA cap (Guanine N-7) methyltransferase0.00006087Direct
PHP domain0.0004035Direct
SAM (sterile alpha motif) domain0.0004948Direct
Carbonic anhydrase0.001222Inherited
Cofactor-dependent phosphoglycerate mutase0.001857Inherited
AraD-like aldolase/epimerase0.002498Inherited
Trehalose-6-phosphate synthase, OtsA0.005568Inherited
Canonical RBD0.01701Inherited
Starch-binding domain0.02867Inherited
Phosphate binding protein-like1Inherited
Nucleotide and nucleoside kinases1Inherited
PLC-like (P variant)1Inherited

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Voltage-gated potassium channels0Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0Direct
ComB-like0Direct
Protein serine/threonine phosphatase 2C, C-terminal domain0Direct
(Phosphotyrosine protein) phosphatases II0Direct
Carbohydrate phosphatase0Direct
Phosphoglycerate mutase-like0Direct
Phosphotyrosine protein phosphatases I0Direct
Sulfolobus fructose-1,6-bisphosphatase-like0Direct
Metallo-dependent phosphatases0Direct
CRAL/TRIO N-terminal domain0Direct
PP2C-like0Direct
Rhodanese/Cell cycle control phosphatase0Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0Direct
SurE-like0Direct
CYTH-like phosphatases0Direct
HAD-like0Direct
Bacterial GAP domain0Direct
Fibronectin type III0Direct
Purple acid phosphatase, N-terminal domain0Direct
Immunoglobulin1.78e-16Direct
Second domain of FERM0.00000000000003902Direct
DEK C-terminal domain0.00000000000009823Direct
Macro domain-like0.00000000003002Direct
Ubiquitin-like0.000000001701Direct
GTPase activation domain, GAP0.000000002805Direct
NTF2-like0.000000007016Direct
SH2 domain0.000000789Direct
Chaperone J-domain0.000001639Direct
PH domain-like0.000005818Direct
Kelch motif0.00001395Direct
CRAL/TRIO domain0.00002101Direct
Non-globular alpha+beta subunits of globular proteins0.0002654Direct
FYVE/PHD zinc finger0.0004377Direct
PDZ domain-like0.0006815Direct
TPR-like0.0009114Direct
Carbonic anhydrase0.001344Inherited
DNase I-like0.001393Inherited
SAM/Pointed domain0.002543Inherited
AraD/HMP-PK domain-like0.002964Inherited
Starch-binding domain-like0.01087Inherited
RNA-binding domain, RBD0.01683Inherited
DHH phosphoesterases0.02436Inherited
Thermostable phytase (3-phytase)0.03106Inherited
Alkaline phosphatase-like0.1139Inherited
PHP domain-like0.3358Inherited
Concanavalin A-like lectins/glucanases0.3572Inherited
L domain-like0.6871Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
EF-hand1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited
Periplasmic binding protein-like II1Inherited
alpha/beta-Hydrolases1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
HD-domain/PDEase-like1Inherited
DNA/RNA polymerases1Inherited
Ribosomal protein S5 domain 2-like1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
ACT-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56784,54427
  • 56784 - HAD-like
  • 54427 - NTF2-like
    		• 0Direct
    53639,56784
  • 53639 - AraD/HMP-PK domain-like
  • 56784 - HAD-like
    		• 0Direct
    52821,52799
  • 52821 - Rhodanese/Cell cycle control phosphatase
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
    		• 0Direct
    56219,56219
  • 56219 - DNase I-like
  • 56219 - DNase I-like
    		• 0Direct
    101908,56219
  • 101908 - Putative isomerase YbhE
  • 56219 - DNase I-like
    		• 0Direct
    56784,52540
  • 56784 - HAD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0Direct
    52087,52799
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    52799,56091
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
    		• 0Direct
    52799,52799
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    56568,47233
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
    		• 0Direct
    48452,56300
  • 48452 - TPR-like
  • 56300 - Metallo-dependent phosphatases
    		• 0Direct
    49899,48726
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
    		• 0Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
    		• 0Direct
    81324,52799
  • 81324 - Voltage-gated potassium channels
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    51069,49265
  • 51069 - Carbonic anhydrase
  • 49265 - Fibronectin type III
    		• 0Direct
    49363,56300
  • 49363 - Purple acid phosphatase, N-terminal domain
  • 56300 - Metallo-dependent phosphatases
    		• 0Direct
    56300,47473
  • 56300 - Metallo-dependent phosphatases
  • 47473 - EF-hand
    		• 0Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
    		• 0Direct
    46938,52087
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
    		• 0Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
    		• 0Direct
    55154,56091
  • 55154 - CYTH-like phosphatases
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
    		• 0Direct
    54211,54211
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
    		• 0Direct
    47233,52799
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    50156,52799
  • 50156 - PDZ domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    56784,53474
  • 56784 - HAD-like
  • 53474 - alpha/beta-Hydrolases
    		• 0Direct
    56784,56784
  • 56784 - HAD-like
  • 56784 - HAD-like
    		• 0Direct
    55550,52799
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    56300,56300
  • 56300 - Metallo-dependent phosphatases
  • 56300 - Metallo-dependent phosphatases
    		• 0Direct
    56219,54928
  • 56219 - DNase I-like
  • 54928 - RNA-binding domain, RBD
    		• 0Direct
    56300,55816
  • 56300 - Metallo-dependent phosphatases
  • 55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
    		• 0Direct
    56784,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
    		• 0Direct
    49452,52799
  • 49452 - Starch-binding domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    81606,81601
  • 81606 - PP2C-like
  • 81601 - Protein serine/threonine phosphatase 2C, C-terminal domain
    		• 0Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
    		• 0Direct
    109715,52799
  • 109715 - DEK C-terminal domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    50729,52799
  • 50729 - PH domain-like
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    54236,56784
  • 54236 - Ubiquitin-like
  • 56784 - HAD-like
    		• 0Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
    		• 0.00000000000000246Direct
    53335,52949
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 52949 - Macro domain-like
    		• 0.00000000000001114Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
    		• 0.0000001085Direct
    53756,56784
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 56784 - HAD-like
    		• 0.000001924Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
    		• 0.0003289Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
    		• 0.01125Inherited
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
    		• 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49265,49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
    		• 0Direct
    56784,54211,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
    		• 0Direct
    56568,47233,52799
  • 56568 - Non-globular alpha+beta subunits of globular proteins
  • 47233 - Bacterial GAP domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
    		• 0Direct
    55550,55550,52799
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    49899,48726,49265
  • 49899 - Concanavalin A-like lectins/glucanases
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
    		• 0Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
    		• 0Direct
    52799,56091,50249
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
    		• 0Direct
    81324,52799,49562
  • 81324 - Voltage-gated potassium channels
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
    		• 0Direct
    46938,52087,52799
  • 46938 - CRAL/TRIO N-terminal domain
  • 52087 - CRAL/TRIO domain
  • 52799 - (Phosphotyrosine protein) phosphatases II
    		• 0Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
    		• 7.073e-16Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
    		• 0.000000005321Direct

    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)
    Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

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    © Copyright 2013 The SUPERFAMILY authors and Julian Gough.