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  Home > Phenotype Ontology > Serine endopeptidases

Enzyme Commission (EC): Serine endopeptidases

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Hydrolases [3] <13>(396|669) (395|421|209)
+ 1:   Acting on peptide bonds (peptidases) [3.4] <19>(114|168) (114|129|72)
0:   Serine endopeptidases [3.4.21] <121>(40|45) (40|47|34)
- 1:   3.4.21.67 [3.4.21.14](0|0) (0|0|0)
- 1:   Acrosin [3.4.21.10](1|1) (1|0|0)
- 1:   Alpha-lytic endopeptidase [3.4.21.12](0|0) (0|0|0)
- 1:   Alternative-complement-pathway C3/C5 convertase [3.4.21.47](2|3) (2|3|3)
- 1:   Aqualysin 1 [3.4.21.111](0|0) (0|0|0)
- 1:   Assemblin [3.4.21.97](1|1) (1|0|0)
- 1:   Brachyurin [3.4.21.32](0|0) (0|0|0)
- 1:   C-terminal processing peptidase [3.4.21.102](2|1) (2|1|0)
- 1:   C5a peptidase [3.4.21.110](2|2) (2|1|0)
- 1:   Cathepsin G [3.4.21.20](0|0) (0|0|0)
- 1:   Cerevisin [3.4.21.48](0|0) (0|0|0)
- 1:   Chymase [3.4.21.39](1|1) (1|0|0)
- 1:   Chymotrypsin [3.4.21.1](1|1) (1|0|0)
- 1:   Chymotrypsin C [3.4.21.2](0|0) (0|0|0)
- 1:   Classical-complement-pathway C3/C5 convertase [3.4.21.43](2|3) (2|3|3)
- 1:   Coagulation factor IXa [3.4.21.22](3|3) (3|2|1)
- 1:   Coagulation factor VIIa [3.4.21.21](2|3) (2|2|0)
- 1:   Coagulation factor XIIa [3.4.21.38](2|3) (2|1|0)
- 1:   Coagulation factor XIa [3.4.21.27](0|0) (0|0|0)
- 1:   Coagulation factor Xa [3.4.21.6](4|3) (4|4|1)
- 1:   Complement factor D [3.4.21.46](0|1) (0|0|0)
- 1:   Complement factor I [3.4.21.45](3|2) (3|4|3)
- 1:   Complement subcomponent C1r [3.4.21.41](3|4) (3|5|4)
- 1:   Complement subcomponent C1s [3.4.21.42](3|4) (3|5|4)
- 1:   Cucumisin [3.4.21.25](0|0) (0|0|0)
- 1:   Deleted entry [3.4.21.23](0|0) (0|0|0)
- 1:   Deleted entry [3.4.21.51](0|0) (0|0|0)
- 1:   Deleted entry [3.4.21.56](0|0) (0|0|0)
- 1:   Deleted entry [3.4.21.17](0|0) (0|0|0)
- 1:   Deleted entry [3.4.21.58](0|0) (0|0|0)
- 1:   Deleted entry [3.4.21.33](0|0) (0|0|0)
- 1:   Deleted entry [3.4.21.16](0|0) (0|0|0)
- 1:   Deleted entry [3.4.21.24](0|0) (0|0|0)
- 1:   Deleted entry [3.4.21.40](0|0) (0|0|0)
- 1:   Deleted entry [3.4.21.52](0|0) (0|0|0)
- 1:   Deleted entry [3.4.21.18](0|0) (0|0|0)
- 1:   Endopeptidase Clp [3.4.21.92](1|1) (1|0|0)
- 1:   Endopeptidase La [3.4.21.53](3|3) (3|1|0)
- 1:   Endopeptidase So [3.4.21.67](0|0) (0|0|0)
- 1:   Enteropeptidase [3.4.21.9](5|4) (5|7|6)
- 1:   Equine arterivirus serine peptidase [3.4.21.114](0|0) (0|0|0)
- 1:   Flavivirin [3.4.21.91](7|7) (7|4|1)
- 1:   Furin [3.4.21.75](4|4) (4|3|2)
- 1:   Gamma-renin [3.4.21.54](0|0) (0|0|0)
- 1:   Glutamyl endopeptidase [3.4.21.19](1|1) (1|0|0)
- 1:   Glutamyl endopeptidase II [3.4.21.82](0|0) (0|0|0)
- 1:   Granzyme A [3.4.21.78](0|0) (0|0|0)
- 1:   Granzyme B [3.4.21.79](0|0) (0|0|0)
- 1:   Hepacivirin [3.4.21.98](3|3) (3|2|1)
- 1:   Hepsin [3.4.21.106](1|1) (1|1|0)
- 1:   HtrA2 peptidase [3.4.21.108](2|2) (2|1|0)
- 1:   Hypodermin C [3.4.21.49](0|0) (0|0|0)
- 1:   IgA-specific serine endopeptidase [3.4.21.72](2|1) (2|0|0)
- 1:   Infectious pancreatic necrosis birnavirus Vp4 peptidase [3.4.21.115](0|0) (0|0|0)
- 1:   Kallikrein 13 [3.4.21.119](0|0) (0|0|0)
- 1:   Kallikrein 8 [3.4.21.118](0|0) (0|0|0)
- 1:   Kexin [3.4.21.61](0|0) (0|0|0)
- 1:   Lactocepin [3.4.21.96](2|2) (2|1|0)
- 1:   Leucyl endopeptidase [3.4.21.57](0|0) (0|0|0)
- 1:   Leukocyte elastase [3.4.21.37](0|0) (0|0|0)
- 1:   Limulus clotting enzyme [3.4.21.86](0|0) (0|0|0)
- 1:   Limulus clotting factor B [3.4.21.85](0|0) (0|0|0)
- 1:   Limulus clotting factor C [3.4.21.84](0|0) (0|0|0)
- 1:   Lys-Lys/Arg-Xaa endopeptidase [3.4.21.121](0|0) (0|0|0)
- 1:   Lysyl endopeptidase [3.4.21.50](0|1) (0|0|0)
- 1:   Mannan-binding lectin-associated serine protease-2 [3.4.21.104](3|3) (3|5|4)
- 1:   Matriptase [3.4.21.109](3|2) (3|5|5)
- 1:   Metridin [3.4.21.3](0|0) (0|0|0)
- 1:   Myeloblastin [3.4.21.76](0|0) (0|0|0)
- 1:   Oligopeptidase B [3.4.21.83](0|0) (0|0|0)
- 1:   Oryzin [3.4.21.63](2|2) (2|1|0)
- 1:   Oviductin [3.4.21.120](1|1) (1|2|1)
- 1:   Pancreatic elastase [3.4.21.36](1|1) (1|0|0)
- 1:   Pancreatic elastase II [3.4.21.71](0|1) (0|0|0)
- 1:   Pancreatic endopeptidase E [3.4.21.70](0|0) (0|0|0)
- 1:   Peptidase Do [3.4.21.107](2|2) (2|2|1)
- 1:   Peptidase K [3.4.21.64](0|0) (0|0|0)
- 1:   Pestivirus NS3 polyprotein peptidase [3.4.21.113](3|3) (3|0|0)
- 1:   Physarolisin [3.4.21.103](0|0) (0|0|0)
- 1:   Plasma kallikrein [3.4.21.34](0|0) (0|0|0)
- 1:   Plasmin [3.4.21.7](3|2) (3|3|3)
- 1:   Prolyl oligopeptidase [3.4.21.26](3|4) (3|2|0)
- 1:   Proprotein convertase 1 [3.4.21.93](3|3) (3|2|1)
- 1:   Proprotein convertase 2 [3.4.21.94](3|3) (3|2|1)
- 1:   Protein C (activated) [3.4.21.69](3|3) (3|3|2)
- 1:   Repressor LexA [3.4.21.88](2|2) (2|1|0)
- 1:   Rhomboid protease [3.4.21.105](2|1) (2|0|0)
- 1:   Scutelarin [3.4.21.60](0|0) (0|0|0)
- 1:   Sedolisin [3.4.21.100](0|0) (0|0|0)
- 1:   Semenogelase [3.4.21.77](0|0) (0|0|0)
- 1:   Signal peptidase I [3.4.21.89](1|1) (1|0|0)
- 1:   Site-1 protease [3.4.21.112](1|1) (1|0|0)
- 1:   Snake venom factor V activator [3.4.21.95](0|0) (0|0|0)
- 1:   Spermosin [3.4.21.99](0|0) (0|0|0)
- 1:   SpoIVB peptidase [3.4.21.116](0|0) (0|0|0)
- 1:   Stratum corneum chymotryptic enzyme [3.4.21.117](0|0) (0|0|0)
- 1:   Streptogrisin A [3.4.21.80](0|0) (0|0|0)
- 1:   Streptogrisin B [3.4.21.81](0|0) (0|0|0)
- 1:   Subtilisin [3.4.21.62](2|2) (2|1|0)
- 1:   T-plasminogen activator [3.4.21.68](3|3) (3|3|2)
- 1:   Thermitase [3.4.21.66](0|0) (0|0|0)
- 1:   Thermomycolin [3.4.21.65](0|0) (0|0|0)
- 1:   Thrombin [3.4.21.5](2|3) (2|3|2)
- 1:   Tissue kallikrein [3.4.21.35](1|1) (1|0|0)
- 1:   Togavirin [3.4.21.90](3|3) (3|1|0)
- 1:   Transferred entry: 3.4.16.5 and 3.4.16.6 [3.4.21.13](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.21.34 and 3.4.21.35 [3.4.21.8](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.21.36 and 3.4.21.37 [3.4.21.11](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.21.43 [3.4.21.44](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.21.63 [3.4.21.15](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.21.68 and 3.4.21.73 [3.4.21.31](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.21.74 [3.4.21.28](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.21.74 [3.4.21.29](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.21.74 [3.4.21.30](0|0) (0|0|0)
- 1:   Transferred entry: 3.4.23.49 [3.4.21.87](0|0) (0|0|0)
- 1:   Trypsin [3.4.21.4](1|1) (1|0|0)
- 1:   Tryptase [3.4.21.59](1|1) (1|0|0)
- 1:   U-plasminogen activator [3.4.21.73](2|2) (2|1|0)
- 1:   Venombin A [3.4.21.74](1|1) (1|0|0)
- 1:   Venombin AB [3.4.21.55](0|0) (0|0|0)
- 1:   Xanthomonalisin [3.4.21.101](0|0) (0|0|0)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
"Winged helix" DNA-binding domain0Direct
LDL receptor-like module0Direct
PUA domain-like0Direct
Hairpin loop containing domain-like0Direct
Rhomboid-like0Direct
ClpP/crotonase0Direct
LexA/Signal peptidase0Direct
Flavivirus capsid protein C0Direct
E set domains0Direct
Trypsin-like serine proteases0Direct
SEA domain0Direct
PDZ domain-like0Direct
GLA-domain0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
EGF/Laminin0Direct
Ribosomal protein S5 domain 2-like0Direct
Kazal-type serine protease inhibitors0Direct
Viral glycoprotein, central and dimerisation domains0Direct
SRCR-like0Direct
Herpes virus serine proteinase, assemblin0Direct
FnI-like domain0.000000000000003019Direct
Complement control module/SCR domain0.00000000000003001Direct
Kringle-like0.0000000000001672Direct
vWA-like0.0000000000006845Direct
Autotransporter0.000000000001271Direct
Subtilisin-like0.0000000000231Direct
Spermadhesin, CUB domain0.0000000004118Direct
Growth factor receptor domain0.0000007236Direct
Ribonuclease Rh-like0.00002385Direct
Peptidase/esterase 'gauge' domain0.00007467Direct
Protease propeptides/inhibitors0.001555Inherited
Pectin lyase-like0.2405Inherited
PA domain0.384Inherited
Galactose-binding domain-like0.5538Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.9377Inherited
EF-hand1Inherited
Concanavalin A-like lectins/glucanases1Inherited
alpha/beta-Hydrolases1Inherited
DPP6 N-terminal domain-like1Inherited
DNA/RNA polymerases1Inherited

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Fibronectin type I module0Direct
Viral proteases0Direct
HtrA-like serine proteases0Direct
ATP-dependent protease Lon (La), catalytic domain0Direct
Tail specific protease, catalytic domain0Direct
Rhomboid-like0Direct
Prohormone convertase 1 pro-domain0Direct
SEA domain0Direct
Type 1 signal peptidase0Direct
RNA helicase0Direct
LexA-related0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Hepsin, N-terminal domain0Direct
LON domain-like0Direct
Subtilases0Direct
Class II viral fusion proteins C-terminal domain0Direct
Flavivirus capsid protein C0Direct
Eukaryotic proteases0Direct
LexA repressor, N-terminal DNA-binding domain0Direct
Virulence factor P.69 pertactin0Direct
Prolyl oligopeptidase, N-terminal domain0Direct
GLA-domain0Direct
Clp protease, ClpP subunit0Direct
EGF-type module0Direct
Integrin A (or I) domain0Direct
Herpes virus serine proteinase, assemblin0Direct
mRNA cap methylase0Direct
Prokaryotic proteases0Direct
Extended AAA-ATPase domain0Direct
Prolyl oligopeptidase, C-terminal domain0Direct
LDL receptor-like module0Direct
Kringle modules0Direct
Complement control module/SCR domain0.00000000000001655Direct
Proprotein convertase P-domain0.0000000000006736Direct
Spermadhesin, CUB domain0.0000000002468Direct
Subtilase propeptides/inhibitors0.000000001815Direct
Scavenger receptor cysteine-rich (SRCR) domain0.00000007011Direct
Growth factor receptor domain0.0000004861Direct
Ribonuclease Rh-like0.00002498Direct
RNA-dependent RNA-polymerase0.004325Inherited
MAM domain0.2117Inherited
PA domain0.3406Inherited
Fibronectin type II module0.3855Inherited
DPP6 N-terminal domain-like1Inherited
DPP6 catalytic domain-like1Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
"Winged helix" DNA-binding domain0Direct
ClpP/crotonase0Direct
Flavivirus capsid protein C0Direct
Kazal-type serine protease inhibitors0Direct
EGF/Laminin0Direct
Rhomboid-like0Direct
Herpes virus serine proteinase, assemblin0Direct
SEA domain0Direct
E set domains0Direct
Hairpin loop containing domain-like0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
GLA-domain0Direct
PUA domain-like0Direct
Trypsin-like serine proteases0Direct
LexA/Signal peptidase0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Ribosomal protein S5 domain 2-like0Direct
PDZ domain-like0Direct
SRCR-like0Direct
LDL receptor-like module0Direct
FnI-like domain0.00000000000000211Direct
Complement control module/SCR domain0.00000000000002116Direct
Kringle-like0.0000000000001187Direct
vWA-like0.00000000000049Direct
Autotransporter0.0000000000009124Direct
Subtilisin-like0.0000000000168Direct
Spermadhesin, CUB domain0.0000000003046Direct
Growth factor receptor domain0.0000005627Direct
Ribonuclease Rh-like0.000019Direct
Peptidase/esterase 'gauge' domain0.00005996Direct
Protease propeptides/inhibitors0.001288Inherited
Pectin lyase-like0.2144Inherited
PA domain0.3478Inherited
Galactose-binding domain-like0.5072Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.8668Inherited
DNA/RNA polymerases0.9428Inherited
EF-hand1Inherited
DPP6 N-terminal domain-like1Inherited
Concanavalin A-like lectins/glucanases1Inherited
alpha/beta-Hydrolases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
82671,57424
  • 82671 - SEA domain
  • 57424 - LDL receptor-like module
    		• 0Direct
    50494,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0Direct
    52743,52025
  • 52743 - Subtilisin-like
  • 52025 - PA domain
    		• 0Direct
    100895,56487
  • 100895 - Kazal-type serine protease inhibitors
  • 56487 - SRCR-like
    		• 0Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
    		• 0Direct
    56983,81296
  • 56983 - Viral glycoprotein, central and dimerisation domains
  • 81296 - E set domains
    		• 0Direct
    57603,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
    		• 0Direct
    50156,52096
  • 50156 - PDZ domain-like
  • 52096 - ClpP/crotonase
    		• 0Direct
    53300,50494
  • 53300 - vWA-like
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0Direct
    57424,49854
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
    		• 0Direct
    49854,50494
  • 49854 - Spermadhesin, CUB domain
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
    		• 0Direct
    49854,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
    		• 0Direct
    82671,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
    		• 0Direct
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
    		• 0Direct
    57414,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
    		• 0Direct
    46785,51306
  • 46785 - "Winged helix" DNA-binding domain
  • 51306 - LexA/Signal peptidase
    		• 0Direct
    57184,50494
  • 57184 - Growth factor receptor domain
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    57535,53300
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
    		• 0Direct
    53335,56672
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 56672 - DNA/RNA polymerases
    		• 0Direct
    49899,49854
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
    		• 0Direct
    56487,57424
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
    		• 0Direct
    57440,57196
  • 57440 - Kringle-like
  • 57196 - EGF/Laminin
    		• 0Direct
    57196,50494
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
    		• 0Direct
    57630,57440
  • 57630 - GLA-domain
  • 57440 - Kringle-like
    		• 0Direct
    49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
    		• 0Direct
    50494,50156
  • 50494 - Trypsin-like serine proteases
  • 50156 - PDZ domain-like
    		• 0Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
    		• 0Direct
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    57535,50494
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    52540,54211
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54211 - Ribosomal protein S5 domain 2-like
    		• 0Direct
    57424,50494
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    57630,57184
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
    		• 0Direct
    57424,56487
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
    		• 0Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    49854,49899
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
    		• 0Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
    		• 0.00000000000002116Direct
    57196,49854
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
    		• 0.0000000197Direct
    49854,57196
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
    		• 0.0000000197Direct
    54897,52743
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
    		• 0.0000001296Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
    		• 0.000001224Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
    		• 0.00003292Direct
    50993,53474
  • 50993 - Peptidase/esterase 'gauge' domain
  • 53474 - alpha/beta-Hydrolases
    		• 0.00005996Direct
    49854,49854
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
    		• 0.01918Inherited
    82171,53474
  • 82171 - DPP6 N-terminal domain-like
  • 53474 - alpha/beta-Hydrolases
    		• 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57603,57440,57440
  • 57603 - FnI-like domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
    		• 0Direct
    49854,57535,57535
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
    		• 0Direct
    57535,57535,50494
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    57424,57424,50494
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    49854,49899,49854
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
    		• 0Direct
    49854,57424,56487
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
    		• 0Direct
    57630,57196,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
    		• 0Direct
    50494,52540,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
    		• 0Direct
    49899,49854,57424
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
    		• 0Direct
    57196,49854,57535
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
  • 57535 - Complement control module/SCR domain
    		• 0Direct
    49854,49854,50494
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    57535,57535,53300
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
    		• 0Direct
    57196,57196,50494
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    57630,57440,57440
  • 57630 - GLA-domain
  • 57440 - Kringle-like
  • 57440 - Kringle-like
    		• 0Direct
    56487,57424,57424
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
    		• 0Direct
    49854,49854,57424
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
    		• 0Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
    		• 0Direct
    57630,57196,50494
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    57424,56487,50494
  • 57424 - LDL receptor-like module
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    57535,53300,50494
  • 57535 - Complement control module/SCR domain
  • 53300 - vWA-like
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    100895,56487,57424
  • 100895 - Kazal-type serine protease inhibitors
  • 56487 - SRCR-like
  • 57424 - LDL receptor-like module
    		• 0Direct
    82671,49854,49854
  • 82671 - SEA domain
  • 49854 - Spermadhesin, CUB domain
  • 49854 - Spermadhesin, CUB domain
    		• 0Direct
    49854,57424,57424
  • 49854 - Spermadhesin, CUB domain
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
    		• 0Direct
    52743,49785,57184
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
    		• 0Direct
    50494,50156,50156
  • 50494 - Trypsin-like serine proteases
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
    		• 0Direct
    57414,57440,57440
  • 57414 - Hairpin loop containing domain-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
    		• 0Direct
    57630,57184,50494
  • 57630 - GLA-domain
  • 57184 - Growth factor receptor domain
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    82671,57424,49854
  • 82671 - SEA domain
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
    		• 0Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
    		• 0Direct
    57424,49854,49899
  • 57424 - LDL receptor-like module
  • 49854 - Spermadhesin, CUB domain
  • 49899 - Concanavalin A-like lectins/glucanases
    		• 0Direct
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
    		• 0Direct
    49854,57196,49854
  • 49854 - Spermadhesin, CUB domain
  • 57196 - EGF/Laminin
  • 49854 - Spermadhesin, CUB domain
    		• 0.0000000197Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
    		• 0.0000006545Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
    		• 0.07365Inherited

    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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    Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

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    © Copyright 2013 The SUPERFAMILY authors and Julian Gough.