SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

  Home > Phenotype Ontology > Acid--ammonia (or amine) ligases (amide synthases)

Enzyme Commission (EC): Acid--ammonia (or amine) ligases (amide synthases)

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <7>
+ + 2:   Ligases [6] <6>(98|123) (97|115|71)
+ 1:   Forming carbon-nitrogen bonds [6.3] <5>(59|78) (58|59|38)
0:   Acid--ammonia (or amine) ligases (amide synthases) [6.3.1] <20>(8|11) (8|4|1)
- 1:   4-methyleneglutamate--ammonia ligase [6.3.1.7](0|0) (0|0|0)
- 1:   8-demethylnovobiocic acid synthase [6.3.1.15](0|0) (0|0|0)
- 1:   Adenosylcobinamide-phosphate synthase [6.3.1.10](0|0) (0|0|0)
- 1:   Aspartate--ammonia ligase [6.3.1.1](1|1) (1|0|0)
- 1:   Aspartate--ammonia ligase (ADP-forming) [6.3.1.4](0|0) (0|0|0)
- 1:   Beta-citrylglutamate synthase [6.3.1.17](1|0) (1|0|0)
- 1:   D-aspartate ligase [6.3.1.12](0|0) (0|0|0)
- 1:   Diphthine--ammonia ligase [6.3.1.14](0|0) (0|0|0)
- 1:   Gamma-glutamylanilide synthase [6.3.1.18](0|0) (0|0|0)
- 1:   Glutamate--ethylamine ligase [6.3.1.6](0|0) (0|0|0)
- 1:   Glutamate--putrescine ligase [6.3.1.11](0|0) (0|0|0)
- 1:   Glutamine synthetase [6.3.1.2](2|2) (2|1|0)
- 1:   Glutathionylspermidine synthase [6.3.1.8](0|0) (0|0|0)
- 1:   Lipoate--protein ligase [6.3.1.20](2|2) (2|1|0)
- 1:   NAD(+) synthase [6.3.1.5](1|1) (1|0|0)
- 1:   Prokaryotic ubiquitin-like protein ligase [6.3.1.19](0|0) (0|0|0)
- 1:   Transferred entry: 6.3.3.6 [6.3.1.16](0|0) (0|0|0)
- 1:   Transferred entry: 6.3.4.13 [6.3.1.3](0|0) (0|0|0)
- 1:   Trypanothione synthase [6.3.1.9](0|0) (0|0|0)
- 1:   ligase [6.3.1.13](2|2) (2|1|0)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Glutamine synthetase, N-terminal domain0Direct
Glutamine synthetase/guanido kinase0Direct
Class II aaRS and biotin synthetases0Direct
SufE/NifU0Direct
Adenine nucleotide alpha hydrolases-like0.000000000000003019Direct
Nucleotidylyl transferase0.00000001053Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Glutathionylspermidine synthase substrate-binding domain-like0Direct
N-type ATP pyrophosphatases0Direct
SP1160 C-terminal domain-like0Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0Direct
Glutamine synthetase, N-terminal domain0Direct
Glutathionylspermidine synthase ATP-binding domain-like0Direct
CHAP domain0Direct
LplA-like0Direct
Glutamine synthetase catalytic domain0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.9868Inherited

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Glutamine synthetase, N-terminal domain0Direct
Glutamine synthetase/guanido kinase0Direct
SufE/NifU0Direct
Class II aaRS and biotin synthetases0Direct
Adenine nucleotide alpha hydrolases-like0.00000000000000211Direct
Nucleotidylyl transferase0.000000007952Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.9312Inherited
Glutathione synthetase ATP-binding domain-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54001,56059
  • 54001 - Cysteine proteinases
  • 56059 - Glutathione synthetase ATP-binding domain-like
    		• 0Direct
    54368,55931
  • 54368 - Glutamine synthetase, N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
    		• 0Direct
    55681,82649
  • 55681 - Class II aaRS and biotin synthetases
  • 82649 - SufE/NifU
    		• 0Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
    		• 0.4994Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54001,56059,52440
  • 54001 - Cysteine proteinases
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52440 - PreATP-grasp domain
    		• 0Direct

    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)
    Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

    Please send feedback, comments or questions to superfamily@cs.bris.ac.uk or use the feedback form.

    © Copyright 2013 The SUPERFAMILY authors and Julian Gough.