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Fly Anatomy (FA): organism
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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: FA Hierarchy (fly anatomy from FlyBase anatomy ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this FA term (Not in SDFA)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
L30e-like | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
DNA-binding domain | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
dsRNA-binding domain-like | 0 | DIRECT |
S15/NS1 RNA-binding domain | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
Nucleotidylyl transferase | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Orange domain-like | 0 | DIRECT |
ARID-like | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
SNARE-like | 0 | DIRECT |
Alkaline phosphatase-like | 0 | DIRECT |
4Fe-4S ferredoxins | 0 | DIRECT |
Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
BAR/IMD domain-like | 0 | DIRECT |
p53-like transcription factors | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
RNI-like | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
Glutamine synthetase/guanido kinase | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
Ribonuclease H-like | 0 | DIRECT |
lambda repressor-like DNA-binding domains | 0 | DIRECT |
PIN domain-like | 0 | DIRECT |
(Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
TIMP-like | 0 | DIRECT |
SAND domain-like | 0 | DIRECT |
SMAD/FHA domain | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
beta-sandwich domain of Sec23/24 | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
C-type lectin-like | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
PapD-like | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
MIR domain | 0 | DIRECT |
2Fe-2S ferredoxin-like | 0 | DIRECT |
Cullin repeat-like | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
PX domain | 0 | DIRECT |
TSP-1 type 1 repeat | 0 | DIRECT |
L27 domain | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
FabD/lysophospholipase-like | 0 | DIRECT |
CAD & PB1 domains | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
Serpins | 0 | DIRECT |
GINS helical bundle-like | 0 | DIRECT |
Putative DNA-binding domain | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
Mob1/phocein | 0 | DIRECT |
TRAF domain-like | 0 | DIRECT |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
Sema domain | 0 | DIRECT |
Periplasmic binding protein-like I | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
MFS general substrate transporter | 0 | DIRECT |
Metallo-dependent phosphatases | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
BRCT domain | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
TATA-box binding protein-like | 0 | DIRECT |
Toll/Interleukin receptor TIR domain | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Kazal-type serine protease inhibitors | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
Arginase/deacetylase | 0 | DIRECT |
UDP-Glycosyltransferase/glycogen phosphorylase | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
ACP-like | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
Clavaminate synthase-like | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
TPR-like | 0 | DIRECT |
Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
HMG-box | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
SAP domain | 0 | DIRECT |
Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
SIS domain | 0 | DIRECT |
(Trans)glycosidases | 0 | DIRECT |
EGF/Laminin | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
Snake toxin-like | 0 | DIRECT |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
Protein prenylyltransferase | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
L domain-like | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
R3H domain | 0 | DIRECT |
cAMP-binding domain-like | 0 | DIRECT |
Class I glutamine amidotransferase-like | 0 | DIRECT |
FKBP-like | 0 | DIRECT |
Terpenoid synthases | 0 | DIRECT |
Sm-like ribonucleoproteins | 0 | DIRECT |
NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
WW domain | 0 | DIRECT |
PriA/YqbF domain | 0 | DIRECT |
alpha-catenin/vinculin-like | 0 | DIRECT |
Actin depolymerizing proteins | 0 | DIRECT |
SNF-like | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
DNA/RNA polymerases | 0 | DIRECT |
Translation proteins SH3-like domain | 0 | DIRECT |
SCOP hierarchy in SUPERFAMILY | 0 | DIRECT |
DNase I-like | 0 | DIRECT |
Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
PDZ domain-like | 0 | DIRECT |
SAM/Pointed domain | 0 | DIRECT |
vWA-like | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
Caspase-like | 0 | DIRECT |
RNase III domain-like | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
HAD-like | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
Concanavalin A-like lectins/glucanases | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
Nuclear receptor ligand-binding domain | 0 | DIRECT |
PAP/OAS1 substrate-binding domain | 0 | DIRECT |
Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
post-AAA+ oligomerization domain-like | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
GTPase activation domain, GAP | 0 | DIRECT |
Ribosomal protein S5 domain 2-like | 0 | DIRECT |
Riboflavin synthase domain-like | 0 | DIRECT |
FnI-like domain | 0 | DIRECT |
HIT/MYND zinc finger-like | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
PAZ domain | 0 | DIRECT |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Rhomboid-like | 0 | DIRECT |
Cytokine | 0 | DIRECT |
DEATH domain | 0 | DIRECT |
RCC1/BLIP-II | 0 | DIRECT |
Protein kinase-like (PK-like) | 0.00286 | INHERITED FROM: somatic cell of ovariole || pupa || intestinal stem cell || nervous system || pupal/adult digestive system || ovariole || embryo || female-specific anatomical entity || larval imaginal tissue || imaginal disc || embryonic/larval integumentary system || egg || synaptic neuropil |
beta-beta-alpha zinc fingers | 0.008375 | INHERITED FROM: thoracic segment || adult || adult mesothoracic segment || subesophageal ganglion neuron || integumentary system || adult thoracic segment || organ system || serotonergic neuron || adult integumentary system || thorax || tagma || adult segment || adult tagma || region of integument || adult thorax || appendage |
Homeodomain-like | 0.09134 | INHERITED FROM: U neuron || embryonic brain || metathoracic ventral denticle belt || dorsal rim area || antennal lobe glomerulus VA1v || head bristle || presumptive embryonic/larval nervous system || presumptive embryonic/larval central nervous system || integumentary process || ventral nerve cord primordium || antenna || embryonic/larval neuron || trunk mesoderm derivative || gnathal segment || larval abdomen || ventral nervous system || developing embryonic structure || integument of larval mesothoracic segment || proboscis || tritocerebrum || A1-7 ventral acute muscle 1 || embryonic/larval dorsal vessel || EL neuron || gonadal sheath proper primordium || embryonic/larval supraesophageal ganglion || adult || wing hinge || embryonic protocerebrum || T1 beard || segment of leg || embryonic segment || adult metathoracic segment || pretarsus || maxillary palpus || adult antennal segment || abdomen || mesothoracic tergum || embryonic/larval subesophageal ganglion || female terminalia || thoracic neuroblast || embryonic tagma || embryonic mesothoracic segment || embryonic thoracic segment || central brain || embryonic/larval sensillum || ganglion || embryonic neuroblast || integumentary system || parasegment || mouthpart || embryonic/larval muscle system || basiproboscis || embryonic/larval thoracic/abdominal lateral sensory cluster || stomatogastric nervous system || extended germ band embryo || tract neuropil || antennal segment || metathoracic segment || prothoracic ventral intersegmental muscle || embryonic head segment || head capsule || organ system || embryonic fiber tract founder cluster || dorsal margin ommatidium || appendage segment || adult integumentary system || neuron projection bundle || uniglomerular antennal lobe projection neuron || thorax || distiproboscis || tagma || adult segment || alula || intercalary segment || embryonic/larval sense organ || head segment || larval metathoracic segment || adult external head || denticle belt || embryonic supraesophageal neuromere || region of integument || larval neuromere || larval segment || transverse nerve || embryonic head || dorsal margin photoreceptor || commissure || adult thorax || larval tagma || interneuron || appendage || larval prothoracic segment || abdominal segment |
P-loop containing nucleoside triphosphate hydrolases | 0.1976 | INHERITED FROM: gonad || reproductive system |
PH domain-like | 0.2258 | INHERITED FROM: embryonic foregut |
RING/U-box | 0.44 | INHERITED FROM: garland cell || embryonic/larval garland organ || embryonic/larval garland cell |
Fibronectin type III | 0.4679 | INHERITED FROM: neuron projection bundle of ventral nerve cord || procephalic segment || larval abdomen || s-LNv neuron || embryonic heart cardioblast || LN period neuron || lobe system of adult mushroom body || leg taste bristle chemosensory neuron || tract neuropil || neuron projection bundle || adult pacemaker neuron || pacemaker neuron || synaptic neuropil || commissure || larval tagma || LNv neuron |
Ankyrin repeat | 0.5507 | INHERITED FROM: Johnston organ neuron |
E set domains | 0.6176 | INHERITED FROM: embryonic hemocyte || head mesoderm derived embryonic hemocyte || embryonic hemocoel |
SH2 domain | 0.6445 | INHERITED FROM: histaminergic neuron || adult optic lobe neuron || ommatidium || embryonic midline of ventral nerve cord || head sensillum || photoreceptor cell R7 || cyst progenitor cell || adult peripheral nervous system || egg chamber || midline || adult segment || photoreceptor cell || embryonic/larval integumentary system || rhabdomeric photoreceptor cell || midline crossing tract |
POZ domain | 0.6777 | INHERITED FROM: terminal filament |
Cysteine-rich domain | 0.7626 | INHERITED FROM: embryonic/larval integumentary system |
Cystine-knot cytokines | 0.7626 | INHERITED FROM: stigmatophore || cephalic furrow || embryonic/larval posterior spiracle || stage 7 embryo || embryonic/larval spiracle |
Calponin-homology domain, CH-domain | 0.7626 | INHERITED FROM: flight muscle || indirect flight muscle |
Tubulin nucleotide-binding domain-like | 0.7881 | INHERITED FROM: spermatid cyst || spermatid || fat cell |
Invertebrate chitin-binding proteins | 0.8162 | INHERITED FROM: tracheal system || embryonic/larval cuticle || primary trachea || embryonic/larval trachea || embryonic/larval tracheal system || embryonic/larval integumentary system || embryonic/larval dorsal trunk |
Cytochrome P450 | 0.8308 | INHERITED FROM: presumptive embryonic/larval nervous system || presumptive embryonic/larval central nervous system || neuropil glial sheath || epidermis || midgut || presumptive embryonic/larval integumentary system || midline glial cell || hindgut || tract || tract neuropil || embryonic/larval foregut || embryonic ventral epidermis || larval VNC neuropil glial cell || embryonic/larval hindgut || larval neuropil glial cell || CNS glial cell || neuropil associated CNS glial cell || embryonic head || midline crossing tract || embryonic/larval glial cell || commissure |
CoA-dependent acyltransferases | 0.8465 | INHERITED FROM: flight muscle || skeletal muscle of mesothorax || adult muscle system || skeletal muscle of thorax || adult somatic muscle |
SET domain | 0.8484 | INHERITED FROM: haltere || metathoracic leg |
Spectrin repeat | 0.866 | INHERITED FROM: neuron projection bundle of ventral nerve cord || copper cell || oocyte || enterocyte || connective || embryonic/larval gut || tract || ipsilateral tract || longitudinal connective || gut epithelial section || gut epithelium || midgut epithelium || fat cell || middle midgut |
ENTH/VHS domain | 0.9032 | INHERITED FROM: disc epithelium proper || imaginal disc epithelial cell |
Leucine zipper domain | 0.9464 | INHERITED FROM: embryonic dorsal epidermis || adult dorsal vessel || adult heart |
Metalloproteases ("zincins"), catalytic domain | 0.9509 | INHERITED FROM: embryonic cardioblast || heart primordium || embryonic heart cardioblast || dorsal vessel primordium |
Immunoglobulin | 0.9915 | INHERITED FROM: neuron projection bundle of ventral nerve cord || procephalic segment || embryonic cardioblast || adult brain || larval abdomen || heart primordium || embryonic heart cardioblast || connective || neuropil glial sheath || abdominal segmental nerve || LN period neuron || nervous system || lobe system of adult mushroom body || dorsal vessel primordium || longitudinal muscle || larval abdominal segment || abdominal nerve || leg taste bristle chemosensory neuron || tract neuropil || neuron projection bundle || central nervous system || adult pacemaker neuron || pacemaker neuron || antennal lobe glomerulus || synaptic neuropil || nerve || commissure || LNv neuron |
SCOP term | FDR (all) | Annotation (direct or inherited) |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
L30e-like | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
DNA-binding domain | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
Bromodomain | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
dsRNA-binding domain-like | 0 | Direct |
S15/NS1 RNA-binding domain | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
Cadherin-like | 0 | Direct |
Smc hinge domain | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
CBS-domain pair | 0 | Direct |
Nucleotidylyl transferase | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Orange domain-like | 0 | Direct |
ARID-like | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
SNARE-like | 0 | Direct |
Alkaline phosphatase-like | 0 | Direct |
4Fe-4S ferredoxins | 0 | Direct |
Rhodanese/Cell cycle control phosphatase | 0 | Direct |
BAR/IMD domain-like | 0 | Direct |
p53-like transcription factors | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
Second domain of FERM | 0 | Direct |
RNI-like | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
Glutamine synthetase/guanido kinase | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
Ribonuclease H-like | 0 | Direct |
lambda repressor-like DNA-binding domains | 0 | Direct |
PIN domain-like | 0 | Direct |
(Phosphotyrosine protein) phosphatases II | 0 | Direct |
TIMP-like | 0 | Direct |
SAND domain-like | 0 | Direct |
SMAD/FHA domain | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
beta-sandwich domain of Sec23/24 | 0 | Direct |
NTF2-like | 0 | Direct |
C-type lectin-like | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
Kelch motif | 0 | Direct |
PapD-like | 0 | Direct |
NHL repeat | 0 | Direct |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
MIR domain | 0 | Direct |
2Fe-2S ferredoxin-like | 0 | Direct |
Cullin repeat-like | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
PX domain | 0 | Direct |
TSP-1 type 1 repeat | 0 | Direct |
L27 domain | 0 | Direct |
Tropomyosin | 0 | Direct |
FabD/lysophospholipase-like | 0 | Direct |
CAD & PB1 domains | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
Serpins | 0 | Direct |
GINS helical bundle-like | 0 | Direct |
Putative DNA-binding domain | 0 | Direct |
Chromo domain-like | 0 | Direct |
Mob1/phocein | 0 | Direct |
TRAF domain-like | 0 | Direct |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
Sema domain | 0 | Direct |
Periplasmic binding protein-like I | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
MFS general substrate transporter | 0 | Direct |
Metallo-dependent phosphatases | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
BRCT domain | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
TATA-box binding protein-like | 0 | Direct |
Toll/Interleukin receptor TIR domain | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Kazal-type serine protease inhibitors | 0 | Direct |
t-snare proteins | 0 | Direct |
Arginase/deacetylase | 0 | Direct |
UDP-Glycosyltransferase/glycogen phosphorylase | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
ACP-like | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
Clavaminate synthase-like | 0 | Direct |
Integrin domains | 0 | Direct |
SPOC domain-like | 0 | Direct |
TPR-like | 0 | Direct |
Nucleotide-diphospho-sugar transferases | 0 | Direct |
HMG-box | 0 | Direct |
Plexin repeat | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
SAP domain | 0 | Direct |
Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
SIS domain | 0 | Direct |
(Trans)glycosidases | 0 | Direct |
EGF/Laminin | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
Snake toxin-like | 0 | Direct |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
Ferritin-like | 0 | Direct |
Protein prenylyltransferase | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
YWTD domain | 0 | Direct |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
L domain-like | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
R3H domain | 0 | Direct |
cAMP-binding domain-like | 0 | Direct |
Class I glutamine amidotransferase-like | 0 | Direct |
FKBP-like | 0 | Direct |
Terpenoid synthases | 0 | Direct |
Sm-like ribonucleoproteins | 0 | Direct |
NAD kinase/diacylglycerol kinase-like | 0 | Direct |
Multidrug resistance efflux transporter EmrE | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
WW domain | 0 | Direct |
PriA/YqbF domain | 0 | Direct |
alpha-catenin/vinculin-like | 0 | Direct |
Actin depolymerizing proteins | 0 | Direct |
SNF-like | 0 | Direct |
SNARE fusion complex | 0 | Direct |
DNA/RNA polymerases | 0 | Direct |
Translation proteins SH3-like domain | 0 | Direct |
SCOP hierarchy in SUPERFAMILY | 0 | Direct |
DNase I-like | 0 | Direct |
Adenine nucleotide alpha hydrolases-like | 0 | Direct |
Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
PDZ domain-like | 0 | Direct |
SAM/Pointed domain | 0 | Direct |
vWA-like | 0 | Direct |
Cap-Gly domain | 0 | Direct |
Caspase-like | 0 | Direct |
RNase III domain-like | 0 | Direct |
Cullin homology domain | 0 | Direct |
HAD-like | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
Concanavalin A-like lectins/glucanases | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
Nuclear receptor ligand-binding domain | 0 | Direct |
PAP/OAS1 substrate-binding domain | 0 | Direct |
Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
post-AAA+ oligomerization domain-like | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
GTPase activation domain, GAP | 0 | Direct |
Ribosomal protein S5 domain 2-like | 0 | Direct |
Riboflavin synthase domain-like | 0 | Direct |
FnI-like domain | 0 | Direct |
HIT/MYND zinc finger-like | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
PAZ domain | 0 | Direct |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Rhomboid-like | 0 | Direct |
Cytokine | 0 | Direct |
DEATH domain | 0 | Direct |
RCC1/BLIP-II | 0 | Direct |
Protein kinase-like (PK-like) | 0.00286 | Inherited |
beta-beta-alpha zinc fingers | 0.008375 | Inherited |
Homeodomain-like | 0.09134 | Inherited |
P-loop containing nucleoside triphosphate hydrolases | 0.1976 | Inherited |
PH domain-like | 0.2258 | Inherited |
RING/U-box | 0.44 | Inherited |
Fibronectin type III | 0.4679 | Inherited |
Ankyrin repeat | 0.5507 | Inherited |
E set domains | 0.6176 | Inherited |
SH2 domain | 0.6445 | Inherited |
POZ domain | 0.6777 | Inherited |
Cysteine-rich domain | 0.7626 | Inherited |
Cystine-knot cytokines | 0.7626 | Inherited |
Calponin-homology domain, CH-domain | 0.7626 | Inherited |
Tubulin nucleotide-binding domain-like | 0.7881 | Inherited |
Invertebrate chitin-binding proteins | 0.8162 | Inherited |
Cytochrome P450 | 0.8308 | Inherited |
CoA-dependent acyltransferases | 0.8465 | Inherited |
SET domain | 0.8484 | Inherited |
Spectrin repeat | 0.866 | Inherited |
ENTH/VHS domain | 0.9032 | Inherited |
Leucine zipper domain | 0.9464 | Inherited |
Metalloproteases ("zincins"), catalytic domain | 0.9509 | Inherited |
Immunoglobulin | 0.9915 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this FA term (Not in SDFA)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
Myb/SANT domain | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
EGF-type module | 0 | DIRECT |
RNase III catalytic domain-like | 0 | DIRECT |
Ngr ectodomain-like | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
Laminin G-like module | 0 | DIRECT |
Isoprenyl diphosphate synthases | 0 | DIRECT |
ets domain | 0 | DIRECT |
NLI interacting factor-like phosphatase | 0 | DIRECT |
MSP-like | 0 | DIRECT |
Caspase catalytic domain | 0 | DIRECT |
FHA domain | 0 | DIRECT |
Calmodulin-like | 0 | DIRECT |
Paired domain | 0 | DIRECT |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
SNF-like | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
BC ATP-binding domain-like | 0 | DIRECT |
Eps15 homology domain (EH domain) | 0 | DIRECT |
Nucleosome core histones | 0 | DIRECT |
Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | DIRECT |
Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | DIRECT |
DnaQ-like 3'-5' exonuclease | 0 | DIRECT |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
Third domain of FERM | 0 | DIRECT |
p120GAP domain-like | 0 | DIRECT |
CAD domain | 0 | DIRECT |
Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
Single strand DNA-binding domain, SSB | 0 | DIRECT |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
C-type lectin domain | 0 | DIRECT |
N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
Rel/Dorsal transcription factors, DNA-binding domain | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
Tubulin, C-terminal domain | 0 | DIRECT |
CoA-binding domain | 0 | DIRECT |
6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | DIRECT |
MBT repeat | 0 | DIRECT |
PAZ domain | 0 | DIRECT |
DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
Dual specificity phosphatase-like | 0 | DIRECT |
Protein prenylyltransferase | 0 | DIRECT |
SAM (sterile alpha motif) domain | 0 | DIRECT |
Phosphotyrosine-binding domain (PTB) | 0 | DIRECT |
Pyk2-associated protein beta ARF-GAP domain | 0 | DIRECT |
Tandem AAA-ATPase domain | 0 | DIRECT |
First domain of FERM | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
R3H domain | 0 | DIRECT |
DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
Erythroid transcription factor GATA-1 | 0 | DIRECT |
Choline/Carnitine O-acyltransferase | 0 | DIRECT |
BCR-homology GTPase activation domain (BH-domain) | 0 | DIRECT |
Dachshund-homology domain | 0 | DIRECT |
RecA protein-like (ATPase-domain) | 0 | DIRECT |
Fibroblast growth factors (FGF) | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
PDZ domain | 0 | DIRECT |
Proteasome subunits | 0 | DIRECT |
PX domain | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
Thioltransferase | 0 | DIRECT |
BAR domain | 0 | DIRECT |
N-acetyl transferase, NAT | 0 | DIRECT |
Nuclear receptor ligand-binding domain | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
Serpins | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Myotubularin-like phosphatases | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
TSP-1 type 1 repeat | 0 | DIRECT |
Synaptotagmin-like (S variant) | 0 | DIRECT |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
SPRY domain | 0 | DIRECT |
Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
HMG-box | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
DEATH domain, DD | 0 | DIRECT |
VHS domain | 0 | DIRECT |
Forkhead DNA-binding domain | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
Pyridoxal-dependent decarboxylase | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
ARID domain | 0 | DIRECT |
Clathrin coat assembly domain | 0 | DIRECT |
Cofilin-like | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
Toll/Interleukin receptor TIR domain | 0 | DIRECT |
Cadherin | 0 | DIRECT |
Tyrosine-dependent oxidoreductases | 0 | DIRECT |
Protein kinases, catalytic subunit | 0 | DIRECT |
SMAD domain | 0 | DIRECT |
Class II glutamine amidotransferases | 0 | DIRECT |
Pleckstrin-homology domain (PH domain) | 0 | DIRECT |
LIM domain | 0 | DIRECT |
ZZ domain | 0 | DIRECT |
PLC-like (P variant) | 0 | DIRECT |
Regulator of chromosome condensation RCC1 | 0 | DIRECT |
Diacylglycerol kinase-like | 0 | DIRECT |
Extended AAA-ATPase domain | 0 | DIRECT |
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | DIRECT |
Diap1 N-terninal region-like | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
Pointed domain | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
Neutral endopeptidase (neprilysin) | 0 | DIRECT |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
Extracellular domain of cell surface receptors | 0 | DIRECT |
BC N-terminal domain-like | 0 | DIRECT |
Histone deacetylase, HDAC | 0 | DIRECT |
Transforming growth factor (TGF)-beta | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
Sema domain | 0 | DIRECT |
Hairy Orange domain | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
L27 domain | 0 | DIRECT |
EF-hand modules in multidomain proteins | 0 | DIRECT |
Elongation factors | 0 | DIRECT |
WW domain | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
Laminin-type module | 0 | DIRECT |
POU-specific domain | 0 | DIRECT |
Tetramerization domain of potassium channels | 0 | DIRECT |
Armadillo repeat | 0 | DIRECT |
Tetratricopeptide repeat (TPR) | 0 | DIRECT |
Mob1/phocein | 0 | DIRECT |
Rhomboid-like | 0 | DIRECT |
Chromo barrel domain | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
Transcriptional factor domain | 0 | DIRECT |
SAP domain | 0 | DIRECT |
L-arabinose binding protein-like | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
T-box | 0 | DIRECT |
Pepsin-like | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
FKBP immunophilin/proline isomerase | 0 | DIRECT |
Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
Ras-binding domain, RBD | 0 | DIRECT |
Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
Phosphate binding protein-like | 0 | DIRECT |
2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
Zf-UBP | 0 | DIRECT |
Cullin repeat | 0 | DIRECT |
PIWI domain | 0 | DIRECT |
acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
cAMP-binding domain | 0 | DIRECT |
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
Nucleotide and nucleoside kinases | 0 | DIRECT |
Protein serine/threonine phosphatase | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Arrestin/Vps26-like | 0 | DIRECT |
Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
TATA-box binding protein (TBP), C-terminal domain | 0 | DIRECT |
Histone lysine methyltransferases | 0 | DIRECT |
acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
THAP domain | 0 | DIRECT |
Motor proteins | 0 | DIRECT |
Nuclear receptor | 0 | DIRECT |
Homeodomain | 0 | DIRECT |
Chromo domain | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Clathrin adaptor core protein | 0 | DIRECT |
Classic zinc finger, C2H2 | 0.1248 | INHERITED FROM: adult || adult mesothoracic segment || integumentary system || adult integumentary system || thorax || embryonic ganglion mother cell || adult segment || adult tagma || embryonic/larval head sensillum || region of integument || adult thorax || appendage |
Fibronectin type III | 0.4443 | INHERITED FROM: neuron projection bundle of ventral nerve cord || procephalic segment || larval abdomen || s-LNv neuron || gustatory receptor neuron || embryonic heart cardioblast || LN period neuron || lobe system of adult mushroom body || tract neuropil || neuron projection bundle || adult pacemaker neuron || pacemaker neuron || synaptic neuropil || nerve || commissure || larval tagma || LNv neuron |
Ankyrin repeat | 0.5305 | INHERITED FROM: Johnston organ neuron || ventral multidendritic neuron |
G proteins | 0.6017 | INHERITED FROM: hemocyte || wing hair || circulatory system || embryonic/larval fat body || embryonic/larval adipose system |
SH2 domain | 0.6215 | INHERITED FROM: histaminergic neuron || adult optic lobe neuron || ommatidium || embryonic midline of ventral nerve cord || head sensillum || photoreceptor cell R7 || cyst progenitor cell || adult peripheral nervous system || egg chamber || midline || adult segment || photoreceptor cell || rhabdomeric photoreceptor cell || midline crossing tract |
BTB/POZ domain | 0.6646 | INHERITED FROM: adult abdominal segment || terminal filament || adult antennal segment || prothoracic tarsal segment |
I set domains | 0.68 | INHERITED FROM: ganglionic branch primordium || embryonic somatic muscle || procephalic segment || embryonic cardioblast || adult brain || larval abdominal sensory neuron || visceral mesoderm derivative || larval abdomen || s-LNv neuron || gustatory receptor neuron || heart primordium || embryonic heart cardioblast || mechanosensory system neuron || connective || neuropil glial sheath || visceral muscle fiber || interface glial cell || lobe system of adult mushroom body || dorsal vessel primordium || adult cerebral ganglion || leg taste bristle chemosensory neuron || embryonic/larval thoracic/abdominal lateral sensory cluster || tract neuropil || neuron projection bundle || adult head segment || adult pacemaker neuron || gustatory system neuron || head segment || pacemaker neuron || adult descending neuron || adult central nervous system || antennal lobe glomerulus || synaptic neuropil || embryonic/larval lateral glial cell || synaptic neuropil subdomain || commissure || synaptic neuropil block || LNv neuron |
Ubiquitin-related | 0.6843 | INHERITED FROM: mushroom body extrinsic neuron |
Cyclin | 0.7099 | INHERITED FROM: germarium |
Calponin-homology domain, CH-domain | 0.7443 | INHERITED FROM: flight muscle || abdominal segmental nerve || indirect flight muscle |
Tubulin, GTPase domain | 0.7684 | INHERITED FROM: spermatid cyst || spermatid || fat cell |
LDL receptor-like module | 0.8152 | INHERITED FROM: embryonic/larval dorsal trunk |
Cytochrome P450 | 0.8152 | INHERITED FROM: presumptive embryonic/larval nervous system || presumptive embryonic/larval central nervous system || neuropil glial sheath || epidermis || midgut || presumptive embryonic/larval integumentary system || midline glial cell || hindgut || tract || tract neuropil || embryonic/larval foregut || embryonic ventral epidermis || larval VNC neuropil glial cell || embryonic/larval hindgut || larval neuropil glial cell || CNS glial cell || neuropil associated CNS glial cell || embryonic head || midline crossing tract || embryonic/larval glial cell || commissure |
Spectrin repeat | 0.854 | INHERITED FROM: neuron projection bundle of ventral nerve cord || copper cell || oocyte || enterocyte || connective || embryonic/larval gut || tract || ipsilateral tract || embryonic/larval alimentary canal || longitudinal connective || gut epithelial section || gut epithelium || midgut epithelium || fat cell || middle midgut |
Leucine zipper domain | 0.9407 | INHERITED FROM: embryonic dorsal epidermis || adult heart |
SCOP term | FDR (all) | Annotation (direct or inherited) |
Myb/SANT domain | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
EGF-type module | 0 | Direct |
RNase III catalytic domain-like | 0 | Direct |
Ngr ectodomain-like | 0 | Direct |
Cap-Gly domain | 0 | Direct |
Laminin G-like module | 0 | Direct |
Isoprenyl diphosphate synthases | 0 | Direct |
ets domain | 0 | Direct |
NLI interacting factor-like phosphatase | 0 | Direct |
MSP-like | 0 | Direct |
Caspase catalytic domain | 0 | Direct |
FHA domain | 0 | Direct |
Calmodulin-like | 0 | Direct |
Paired domain | 0 | Direct |
Transducin (alpha subunit), insertion domain | 0 | Direct |
Higher-molecular-weight phosphotyrosine protein phosphatases | 0 | Direct |
NHL repeat | 0 | Direct |
SNF-like | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
BC ATP-binding domain-like | 0 | Direct |
Eps15 homology domain (EH domain) | 0 | Direct |
Nucleosome core histones | 0 | Direct |
Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | Direct |
Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | Direct |
DnaQ-like 3'-5' exonuclease | 0 | Direct |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
Third domain of FERM | 0 | Direct |
p120GAP domain-like | 0 | Direct |
CAD domain | 0 | Direct |
Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
Single strand DNA-binding domain, SSB | 0 | Direct |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
C-type lectin domain | 0 | Direct |
N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
Rel/Dorsal transcription factors, DNA-binding domain | 0 | Direct |
Kelch motif | 0 | Direct |
Tubulin, C-terminal domain | 0 | Direct |
CoA-binding domain | 0 | Direct |
6-phosphogluconate dehydrogenase-like, N-terminal domain | 0 | Direct |
MBT repeat | 0 | Direct |
PAZ domain | 0 | Direct |
DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
Dual specificity phosphatase-like | 0 | Direct |
Protein prenylyltransferase | 0 | Direct |
SAM (sterile alpha motif) domain | 0 | Direct |
Phosphotyrosine-binding domain (PTB) | 0 | Direct |
Pyk2-associated protein beta ARF-GAP domain | 0 | Direct |
Tandem AAA-ATPase domain | 0 | Direct |
First domain of FERM | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
R3H domain | 0 | Direct |
DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
SCF ubiquitin ligase complex WHB domain | 0 | Direct |
Erythroid transcription factor GATA-1 | 0 | Direct |
Choline/Carnitine O-acyltransferase | 0 | Direct |
BCR-homology GTPase activation domain (BH-domain) | 0 | Direct |
Dachshund-homology domain | 0 | Direct |
RecA protein-like (ATPase-domain) | 0 | Direct |
Fibroblast growth factors (FGF) | 0 | Direct |
SNARE fusion complex | 0 | Direct |
Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
PDZ domain | 0 | Direct |
Proteasome subunits | 0 | Direct |
PX domain | 0 | Direct |
t-snare proteins | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
Thioltransferase | 0 | Direct |
BAR domain | 0 | Direct |
N-acetyl transferase, NAT | 0 | Direct |
Nuclear receptor ligand-binding domain | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
Cullin homology domain | 0 | Direct |
Serpins | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Myotubularin-like phosphatases | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
TSP-1 type 1 repeat | 0 | Direct |
Synaptotagmin-like (S variant) | 0 | Direct |
FYVE, a phosphatidylinositol-3-phosphate binding domain | 0 | Direct |
YWTD domain | 0 | Direct |
Class I glutamine amidotransferases (GAT) | 0 | Direct |
SPRY domain | 0 | Direct |
Ubiquitin activating enzymes (UBA) | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
HMG-box | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
DEATH domain, DD | 0 | Direct |
VHS domain | 0 | Direct |
Forkhead DNA-binding domain | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
Pyridoxal-dependent decarboxylase | 0 | Direct |
NTF2-like | 0 | Direct |
ARID domain | 0 | Direct |
Clathrin coat assembly domain | 0 | Direct |
Cofilin-like | 0 | Direct |
Tropomyosin | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
Toll/Interleukin receptor TIR domain | 0 | Direct |
Cadherin | 0 | Direct |
Tyrosine-dependent oxidoreductases | 0 | Direct |
Protein kinases, catalytic subunit | 0 | Direct |
SMAD domain | 0 | Direct |
Class II glutamine amidotransferases | 0 | Direct |
Pleckstrin-homology domain (PH domain) | 0 | Direct |
LIM domain | 0 | Direct |
ZZ domain | 0 | Direct |
PLC-like (P variant) | 0 | Direct |
Regulator of chromosome condensation RCC1 | 0 | Direct |
Diacylglycerol kinase-like | 0 | Direct |
Extended AAA-ATPase domain | 0 | Direct |
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | Direct |
Diap1 N-terninal region-like | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
Plexin repeat | 0 | Direct |
Pointed domain | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
Neutral endopeptidase (neprilysin) | 0 | Direct |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
Extracellular domain of cell surface receptors | 0 | Direct |
BC N-terminal domain-like | 0 | Direct |
Histone deacetylase, HDAC | 0 | Direct |
Transforming growth factor (TGF)-beta | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
Sema domain | 0 | Direct |
Hairy Orange domain | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
L27 domain | 0 | Direct |
EF-hand modules in multidomain proteins | 0 | Direct |
Elongation factors | 0 | Direct |
WW domain | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
Laminin-type module | 0 | Direct |
POU-specific domain | 0 | Direct |
Tetramerization domain of potassium channels | 0 | Direct |
Armadillo repeat | 0 | Direct |
Tetratricopeptide repeat (TPR) | 0 | Direct |
Mob1/phocein | 0 | Direct |
Rhomboid-like | 0 | Direct |
Chromo barrel domain | 0 | Direct |
Smc hinge domain | 0 | Direct |
CBS-domain pair | 0 | Direct |
Transcriptional factor domain | 0 | Direct |
SAP domain | 0 | Direct |
L-arabinose binding protein-like | 0 | Direct |
Integrin domains | 0 | Direct |
Bromodomain | 0 | Direct |
T-box | 0 | Direct |
Pepsin-like | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
FKBP immunophilin/proline isomerase | 0 | Direct |
Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
Cell cycle control phosphatase, catalytic domain | 0 | Direct |
Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
Ras-binding domain, RBD | 0 | Direct |
Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
Phosphate binding protein-like | 0 | Direct |
2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
Zf-UBP | 0 | Direct |
Cullin repeat | 0 | Direct |
PIWI domain | 0 | Direct |
acyl-CoA oxidase C-terminal domains | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
cAMP-binding domain | 0 | Direct |
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
Nucleotide and nucleoside kinases | 0 | Direct |
Protein serine/threonine phosphatase | 0 | Direct |
Second domain of FERM | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Arrestin/Vps26-like | 0 | Direct |
Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
TATA-box binding protein (TBP), C-terminal domain | 0 | Direct |
Histone lysine methyltransferases | 0 | Direct |
acyl-CoA oxidase N-terminal domains | 0 | Direct |
THAP domain | 0 | Direct |
Motor proteins | 0 | Direct |
Nuclear receptor | 0 | Direct |
Homeodomain | 0 | Direct |
Chromo domain | 0 | Direct |
MIR domain | 0 | Direct |
Clathrin adaptor core protein | 0 | Direct |
Classic zinc finger, C2H2 | 0.1248 | Inherited |
Fibronectin type III | 0.4443 | Inherited |
Ankyrin repeat | 0.5305 | Inherited |
G proteins | 0.6017 | Inherited |
SH2 domain | 0.6215 | Inherited |
BTB/POZ domain | 0.6646 | Inherited |
I set domains | 0.68 | Inherited |
Ubiquitin-related | 0.6843 | Inherited |
Cyclin | 0.7099 | Inherited |
Calponin-homology domain, CH-domain | 0.7443 | Inherited |
Tubulin, GTPase domain | 0.7684 | Inherited |
LDL receptor-like module | 0.8152 | Inherited |
Cytochrome P450 | 0.8152 | Inherited |
Spectrin repeat | 0.854 | Inherited |
Leucine zipper domain | 0.9407 | Inherited |
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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A presence/absence matrix is generated using protein domain
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if individual trees had been produced. However, this data is extracted from the single
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this FA term (Not in SPFA)
Highlighted in gray are those with FDR>0.001
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Transducin (alpha subunit), insertion domain | 0 | DIRECT |
Multidrug resistance efflux transporter EmrE | 0 | DIRECT |
Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
DBL homology domain (DH-domain) | 0 | DIRECT |
Succinyl-CoA synthetase domains | 0 | DIRECT |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
S15/NS1 RNA-binding domain | 0 | DIRECT |
dsRNA-binding domain-like | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
Retrovirus zinc finger-like domains | 0 | DIRECT |
Growth factor receptor domain | 0 | DIRECT |
FtsH protease domain-like | 0 | DIRECT |
UDP-Glycosyltransferase/glycogen phosphorylase | 0 | DIRECT |
4Fe-4S ferredoxins | 0 | DIRECT |
Smc hinge domain | 0 | DIRECT |
SMAD MH1 domain | 0 | DIRECT |
PDZ domain-like | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
DNase I-like | 0 | DIRECT |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
GTPase activation domain, GAP | 0 | DIRECT |
Sec1/munc18-like (SM) proteins | 0 | DIRECT |
NTF2-like | 0 | DIRECT |
Cytokine | 0 | DIRECT |
PX domain | 0 | DIRECT |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | DIRECT |
SNARE-like | 0 | DIRECT |
GINS helical bundle-like | 0 | DIRECT |
HMG-box | 0 | DIRECT |
ARID-like | 0 | DIRECT |
Concanavalin A-like lectins/glucanases | 0 | DIRECT |
MIR domain | 0 | DIRECT |
Sm-like ribonucleoproteins | 0 | DIRECT |
NAD kinase/diacylglycerol kinase-like | 0 | DIRECT |
Mitochondrial carrier | 0 | DIRECT |
Cadherin-like | 0 | DIRECT |
DNA/RNA polymerases | 0 | DIRECT |
SIS domain | 0 | DIRECT |
PIN domain-like | 0 | DIRECT |
Glycerol-3-phosphate (1)-acyltransferase | 0 | DIRECT |
Plexin repeat | 0 | DIRECT |
Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
SNF-like | 0 | DIRECT |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
Tropomyosin | 0 | DIRECT |
Riboflavin synthase domain-like | 0 | DIRECT |
Orange domain-like | 0 | DIRECT |
Rhodanese/Cell cycle control phosphatase | 0 | DIRECT |
SNARE fusion complex | 0 | DIRECT |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
Kazal-type serine protease inhibitors | 0 | DIRECT |
Terpenoid synthases | 0 | DIRECT |
SAP domain | 0 | DIRECT |
(Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
Glutamine synthetase/guanido kinase | 0 | DIRECT |
Spermadhesin, CUB domain | 0 | DIRECT |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
NHL repeat | 0 | DIRECT |
Clathrin adaptor appendage domain | 0 | DIRECT |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
PapD-like | 0 | DIRECT |
Regulator of G-protein signaling, RGS | 0 | DIRECT |
alpha-catenin/vinculin-like | 0 | DIRECT |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | DIRECT |
Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
TSP-1 type 1 repeat | 0 | DIRECT |
BAR/IMD domain-like | 0 | DIRECT |
Acyl-CoA N-acyltransferases (Nat) | 0 | DIRECT |
RCC1/BLIP-II | 0 | DIRECT |
Complement control module/SCR domain | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
Arginase/deacetylase | 0 | DIRECT |
L30e-like | 0 | DIRECT |
CBS-domain pair | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
GroEL-intermediate domain like | 0 | DIRECT |
Serpins | 0 | DIRECT |
HIT/MYND zinc finger-like | 0 | DIRECT |
PAZ domain | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
Tubulin C-terminal domain-like | 0 | DIRECT |
Acyl-CoA dehydrogenase NM domain-like | 0 | DIRECT |
post-AAA+ oligomerization domain-like | 0 | DIRECT |
Putative DNA-binding domain | 0 | DIRECT |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | DIRECT |
L domain-like | 0 | DIRECT |
GroEL equatorial domain-like | 0 | DIRECT |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
Ribosomal protein S5 domain 2-like | 0 | DIRECT |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
Periplasmic binding protein-like I | 0 | DIRECT |
TIMP-like | 0 | DIRECT |
YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
DEATH domain | 0 | DIRECT |
Protein prenylyltransferase | 0 | DIRECT |
Quinoprotein alcohol dehydrogenase-like | 0 | DIRECT |
Cullin homology domain | 0 | DIRECT |
Alkaline phosphatase-like | 0 | DIRECT |
Rhomboid-like | 0 | DIRECT |
RNase III domain-like | 0 | DIRECT |
TATA-box binding protein-like | 0 | DIRECT |
BRCT domain | 0 | DIRECT |
CRAL/TRIO domain | 0 | DIRECT |
Nuclear receptor ligand-binding domain | 0 | DIRECT |
Translation proteins SH3-like domain | 0 | DIRECT |
Nucleotide-diphospho-sugar transferases | 0 | DIRECT |
Hect, E3 ligase catalytic domain | 0 | DIRECT |
vWA-like | 0 | DIRECT |
cAMP-binding domain-like | 0 | DIRECT |
Clavaminate synthase-like | 0 | DIRECT |
Ferritin-like | 0 | DIRECT |
HAD-like | 0 | DIRECT |
ACP-like | 0 | DIRECT |
FabD/lysophospholipase-like | 0 | DIRECT |
Snake toxin-like | 0 | DIRECT |
Supernatant protein factor (SPF), C-terminal domain | 0 | DIRECT |
Cullin repeat-like | 0 | DIRECT |
2Fe-2S ferredoxin-like | 0 | DIRECT |
Adenine nucleotide alpha hydrolases-like | 0 | DIRECT |
Nucleotidylyl transferase | 0 | DIRECT |
EGF/Laminin | 0 | DIRECT |
Cap-Gly domain | 0 | DIRECT |
Chromo domain-like | 0 | DIRECT |
PriA/YqbF domain | 0 | DIRECT |
L27 domain | 0 | DIRECT |
Caspase-like | 0 | DIRECT |
PYP-like sensor domain (PAS domain) | 0 | DIRECT |
Sema domain | 0 | DIRECT |
FnI-like domain | 0 | DIRECT |
SMAD/FHA domain | 0 | DIRECT |
TRAF domain-like | 0 | DIRECT |
Bromodomain | 0 | DIRECT |
GroEL apical domain-like | 0 | DIRECT |
ArfGap/RecO-like zinc finger | 0 | DIRECT |
B-box zinc-binding domain | 0 | DIRECT |
p53-like transcription factors | 0 | DIRECT |
Kelch motif | 0 | DIRECT |
Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
SAICAR synthase-like | 0 | DIRECT |
MFS general substrate transporter | 0 | DIRECT |
t-snare proteins | 0 | DIRECT |
DNA-binding domain | 0 | DIRECT |
PreATP-grasp domain | 0 | DIRECT |
Toll/Interleukin receptor TIR domain | 0 | DIRECT |
(Trans)glycosidases | 0 | DIRECT |
R3H domain | 0 | DIRECT |
Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
Ypt/Rab-GAP domain of gyp1p | 0 | DIRECT |
FKBP-like | 0 | DIRECT |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
PAP/OAS1 substrate-binding domain | 0 | DIRECT |
Metallo-dependent phosphatases | 0 | DIRECT |
YWTD domain | 0 | DIRECT |
Ribonuclease H-like | 0 | DIRECT |
CAD & PB1 domains | 0 | DIRECT |
SAM/Pointed domain | 0 | DIRECT |
beta-sandwich domain of Sec23/24 | 0 | DIRECT |
TPR-like | 0 | DIRECT |
Actin depolymerizing proteins | 0 | DIRECT |
Ran binding protein zinc finger-like | 0 | DIRECT |
lambda repressor-like DNA-binding domains | 0 | DIRECT |
N-acetylmuramoyl-L-alanine amidase-like | 0 | DIRECT |
C-type lectin-like | 0 | DIRECT |
Mob1/phocein | 0 | DIRECT |
Second domain of FERM | 0 | DIRECT |
Class I glutamine amidotransferase-like | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
WW domain | 0 | DIRECT |
SAND domain-like | 0 | DIRECT |
RNI-like | 0 | DIRECT |
Protein kinase-like (PK-like) | 0.002069 | INHERITED FROM: female-specific anatomical entity || pupa || gut epithelial section || photoreceptor cell R8 of pale ommatidium || larval imaginal tissue || intestinal stem cell || somatic cell of ovariole || synaptic neuropil || pupal/adult digestive system || imaginal disc || embryo || egg || embryonic/larval integumentary system || nervous system || ovariole |
beta-beta-alpha zinc fingers | 0.006165 | INHERITED FROM: organ system || thoracic segment || adult segment || tagma || adult mesothoracic segment || adult || integumentary system || adult tagma || adult thoracic segment || adult integumentary system || region of integument || thorax || adult thorax || subesophageal ganglion neuron || serotonergic neuron || appendage |
Homeodomain-like | 0.07567 | INHERITED FROM: mesothoracic tergum || embryonic fiber tract founder cluster || mesothoracic tibial apical bristle || antennal lobe glomerulus VA1v || commissure || appendage segment || adult external metathorax || dorsal margin photoreceptor || adult abdomen || embryonic/larval digestive system || aorta primordium || hypodermal muscle of prothorax || embryonic tagma || distiproboscis || embryonic/larval labial organ || organ system || embryonic/larval muscle system || abdomen || larval neuromere || embryonic protocerebrum || metathoracic ventral denticle belt || ganglion || head capsule || embryonic supraesophageal neuromere || segment of leg || larval abdomen || presumptive embryonic/larval central nervous system || adult segment || larval abdominal segment || tagma || intercalary segment || integument of larval mesothoracic segment || head bristle || muscle cell || embryonic/larval supraesophageal ganglion || embryonic brain || proboscis || wing hinge || tract neuropil || embryonic head || female terminalia || adult || gnathal segment || transverse nerve || trunk mesoderm derivative || sclerite || integumentary system || basiproboscis || interneuron || pretarsus || head segment || antenna || embryonic/larval sensillum || adult integumentary system || metathoracic segment || ventral nerve cord primordium || dorsal margin ommatidium || central brain || embryonic thoracic segment || embryonic neuroblast || ventral nervous system || embryonic/larval thoracic/abdominal lateral sensory cluster || prothoracic ventral intersegmental muscle || A1-7 ventral acute muscle 1 || adult external head || uniglomerular antennal lobe projection neuron || stomatogastric nervous system || gonadal sheath proper primordium || denticle belt || region of integument || antennal segment || embryonic/larval subesophageal ganglion || maxillary palpus || alula || U neuron || embryonic segment || EL neuron || adult metathoracic segment || terminal filament || adult antennal segment || larval prothoracic segment || larval segment || larval tagma || integumentary process || embryonic thorax || dorsal rim area || thorax || embryonic/larval dorsal vessel || presumptive embryonic/larval nervous system || adult thorax || abdominal segment || larval metathoracic segment || parasegment || embryonic/larval sense organ || embryonic head segment || embryonic/larval neuron || developing embryonic structure || embryonic mesothoracic segment || neuron projection bundle || dorsal metathorax || thoracic neuroblast || T1 beard || mouthpart || extended germ band embryo || appendage || tritocerebrum |
P-loop containing nucleoside triphosphate hydrolases | 0.1721 | INHERITED FROM: reproductive system || gonad |
PH domain-like | 0.1981 | INHERITED FROM: embryonic foregut |
RING/U-box | 0.4076 | INHERITED FROM: garland cell || embryonic/larval garland cell || embryonic/larval garland organ |
Fibronectin type III | 0.4358 | INHERITED FROM: commissure || pacemaker neuron || dendritic arborizing neuron || adult cerebrum || neuron projection bundle of ventral nerve cord || larval abdomen || tract neuropil || s-LNv neuron || synaptic neuropil || embryonic heart cardioblast || adult pacemaker neuron || LNv neuron || embryonic cardioblast || lobe system of adult mushroom body || larval tagma || LN period neuron || neuron projection bundle || leg taste bristle chemosensory neuron || procephalic segment |
Ankyrin repeat | 0.5199 | INHERITED FROM: Johnston organ neuron |
E set domains | 0.5884 | INHERITED FROM: head mesoderm derived embryonic hemocyte || embryonic hemocoel || embryonic hemocyte |
Cyclin-like | 0.6077 | INHERITED FROM: morphogenetic furrow |
SH2 domain | 0.6166 | INHERITED FROM: egg chamber || tract || histaminergic neuron || adult segment || midline crossing tract || adult peripheral nervous system || photoreceptor cell || rhabdomeric photoreceptor cell || embryonic midline of ventral nerve cord || ommatidium || photoreceptor cell R7 || adult optic lobe neuron || embryonic/larval integumentary system || connective || cyst progenitor cell || midline || head sensillum |
POZ domain | 0.6514 | INHERITED FROM: terminal filament |
Calponin-homology domain, CH-domain | 0.7411 | INHERITED FROM: flight muscle || abdominal segmental nerve || indirect flight muscle |
Cysteine-rich domain | 0.7411 | INHERITED FROM: embryonic/larval integumentary system |
Cystine-knot cytokines | 0.7411 | INHERITED FROM: stigmatophore || stage 7 embryo || spiracle || embryonic/larval posterior spiracle || cephalic furrow || embryonic/larval spiracle |
Tubulin nucleotide-binding domain-like | 0.7679 | INHERITED FROM: fat cell || spermatid || spermatid cyst |
Invertebrate chitin-binding proteins | 0.7981 | INHERITED FROM: primary trachea || embryonic/larval tracheal system || tracheal system || embryonic/larval trachea || embryonic/larval cuticle || embryonic/larval integumentary system || embryonic/larval dorsal trunk |
Cytochrome P450 | 0.8134 | INHERITED FROM: commissure || neuropil glial sheath || larval neuropil glial cell || hindgut || tract || embryonic/larval glial cell || presumptive embryonic/larval central nervous system || midline crossing tract || tract neuropil || embryonic head || epidermis || embryonic/larval foregut || presumptive embryonic/larval integumentary system || larval VNC neuropil glial cell || CNS glial cell || midline glial cell || embryonic ventral epidermis || embryonic/larval hindgut || presumptive embryonic/larval nervous system || midgut || neuropil associated CNS glial cell || embryonic/first instar larval cuticle |
LDL receptor-like module | 0.8134 | INHERITED FROM: embryonic/larval dorsal trunk |
CoA-dependent acyltransferases | 0.8302 | INHERITED FROM: flight muscle || adult somatic muscle || skeletal muscle of thorax || adult muscle system || skeletal muscle of mesothorax |
SET domain | 0.8323 | INHERITED FROM: dorsal thoracic disc || metathoracic leg || haltere |
Spectrin repeat | 0.8513 | INHERITED FROM: fat cell || middle midgut || midgut epithelium || gut epithelial section || tract || neuron projection bundle of ventral nerve cord || embryonic/larval alimentary canal || gut epithelium || enterocyte || ipsilateral tract || oocyte || longitudinal connective || copper cell || connective || embryonic/larval gut |
ENTH/VHS domain | 0.892 | INHERITED FROM: eye disc || imaginal disc epithelial cell || disc epithelium proper |
Leucine zipper domain | 0.9384 | INHERITED FROM: adult heart || adult dorsal vessel || embryonic dorsal epidermis |
Metalloproteases ("zincins"), catalytic domain | 0.9433 | INHERITED FROM: heart primordium || embryonic heart cardioblast || embryonic cardioblast || dorsal vessel primordium |
Immunoglobulin | 0.9875 | INHERITED FROM: commissure || pacemaker neuron || nerve || neuropil glial sheath || central nervous system || neuron projection bundle of ventral nerve cord || glial cell || heart primordium || larval abdomen || larval abdominal segment || tract neuropil || abdominal segmental nerve || synaptic neuropil || embryonic heart cardioblast || abdominal nerve || adult brain || adult pacemaker neuron || LNv neuron || embryonic cardioblast || longitudinal muscle || connective || lobe system of adult mushroom body || nervous system || antennal lobe glomerulus || LN period neuron || neuron projection bundle || leg taste bristle chemosensory neuron || dorsal vessel primordium || procephalic segment |
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
Transducin (alpha subunit), insertion domain | 0 | Direct |
Multidrug resistance efflux transporter EmrE | 0 | Direct |
Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
DBL homology domain (DH-domain) | 0 | Direct |
Succinyl-CoA synthetase domains | 0 | Direct |
C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
S15/NS1 RNA-binding domain | 0 | Direct |
dsRNA-binding domain-like | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
Retrovirus zinc finger-like domains | 0 | Direct |
Growth factor receptor domain | 0 | Direct |
FtsH protease domain-like | 0 | Direct |
UDP-Glycosyltransferase/glycogen phosphorylase | 0 | Direct |
4Fe-4S ferredoxins | 0 | Direct |
Smc hinge domain | 0 | Direct |
SMAD MH1 domain | 0 | Direct |
PDZ domain-like | 0 | Direct |
SPOC domain-like | 0 | Direct |
DNase I-like | 0 | Direct |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
GTPase activation domain, GAP | 0 | Direct |
Sec1/munc18-like (SM) proteins | 0 | Direct |
NTF2-like | 0 | Direct |
Cytokine | 0 | Direct |
PX domain | 0 | Direct |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0 | Direct |
SNARE-like | 0 | Direct |
GINS helical bundle-like | 0 | Direct |
HMG-box | 0 | Direct |
ARID-like | 0 | Direct |
Concanavalin A-like lectins/glucanases | 0 | Direct |
MIR domain | 0 | Direct |
Sm-like ribonucleoproteins | 0 | Direct |
NAD kinase/diacylglycerol kinase-like | 0 | Direct |
Mitochondrial carrier | 0 | Direct |
Cadherin-like | 0 | Direct |
DNA/RNA polymerases | 0 | Direct |
SIS domain | 0 | Direct |
PIN domain-like | 0 | Direct |
Glycerol-3-phosphate (1)-acyltransferase | 0 | Direct |
Plexin repeat | 0 | Direct |
Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
SNF-like | 0 | Direct |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
Tropomyosin | 0 | Direct |
Riboflavin synthase domain-like | 0 | Direct |
Orange domain-like | 0 | Direct |
Rhodanese/Cell cycle control phosphatase | 0 | Direct |
SNARE fusion complex | 0 | Direct |
Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
Kazal-type serine protease inhibitors | 0 | Direct |
Terpenoid synthases | 0 | Direct |
SAP domain | 0 | Direct |
(Phosphotyrosine protein) phosphatases II | 0 | Direct |
Glutamine synthetase/guanido kinase | 0 | Direct |
Spermadhesin, CUB domain | 0 | Direct |
Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
NHL repeat | 0 | Direct |
Clathrin adaptor appendage domain | 0 | Direct |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
PapD-like | 0 | Direct |
Regulator of G-protein signaling, RGS | 0 | Direct |
alpha-catenin/vinculin-like | 0 | Direct |
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 0 | Direct |
Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
TSP-1 type 1 repeat | 0 | Direct |
BAR/IMD domain-like | 0 | Direct |
Acyl-CoA N-acyltransferases (Nat) | 0 | Direct |
RCC1/BLIP-II | 0 | Direct |
Complement control module/SCR domain | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
Arginase/deacetylase | 0 | Direct |
L30e-like | 0 | Direct |
CBS-domain pair | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
GroEL-intermediate domain like | 0 | Direct |
Serpins | 0 | Direct |
HIT/MYND zinc finger-like | 0 | Direct |
PAZ domain | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
Tubulin C-terminal domain-like | 0 | Direct |
Acyl-CoA dehydrogenase NM domain-like | 0 | Direct |
post-AAA+ oligomerization domain-like | 0 | Direct |
Putative DNA-binding domain | 0 | Direct |
Thiamin diphosphate-binding fold (THDP-binding) | 0 | Direct |
L domain-like | 0 | Direct |
GroEL equatorial domain-like | 0 | Direct |
Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
Ribosomal protein S5 domain 2-like | 0 | Direct |
Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
Periplasmic binding protein-like I | 0 | Direct |
TIMP-like | 0 | Direct |
YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
DEATH domain | 0 | Direct |
Protein prenylyltransferase | 0 | Direct |
Quinoprotein alcohol dehydrogenase-like | 0 | Direct |
Cullin homology domain | 0 | Direct |
Alkaline phosphatase-like | 0 | Direct |
Rhomboid-like | 0 | Direct |
RNase III domain-like | 0 | Direct |
TATA-box binding protein-like | 0 | Direct |
BRCT domain | 0 | Direct |
CRAL/TRIO domain | 0 | Direct |
Nuclear receptor ligand-binding domain | 0 | Direct |
Translation proteins SH3-like domain | 0 | Direct |
Nucleotide-diphospho-sugar transferases | 0 | Direct |
Hect, E3 ligase catalytic domain | 0 | Direct |
vWA-like | 0 | Direct |
cAMP-binding domain-like | 0 | Direct |
Clavaminate synthase-like | 0 | Direct |
Ferritin-like | 0 | Direct |
HAD-like | 0 | Direct |
ACP-like | 0 | Direct |
FabD/lysophospholipase-like | 0 | Direct |
Snake toxin-like | 0 | Direct |
Supernatant protein factor (SPF), C-terminal domain | 0 | Direct |
Cullin repeat-like | 0 | Direct |
2Fe-2S ferredoxin-like | 0 | Direct |
Adenine nucleotide alpha hydrolases-like | 0 | Direct |
Nucleotidylyl transferase | 0 | Direct |
EGF/Laminin | 0 | Direct |
Cap-Gly domain | 0 | Direct |
Chromo domain-like | 0 | Direct |
PriA/YqbF domain | 0 | Direct |
L27 domain | 0 | Direct |
Caspase-like | 0 | Direct |
PYP-like sensor domain (PAS domain) | 0 | Direct |
Sema domain | 0 | Direct |
FnI-like domain | 0 | Direct |
SMAD/FHA domain | 0 | Direct |
TRAF domain-like | 0 | Direct |
Bromodomain | 0 | Direct |
GroEL apical domain-like | 0 | Direct |
ArfGap/RecO-like zinc finger | 0 | Direct |
B-box zinc-binding domain | 0 | Direct |
p53-like transcription factors | 0 | Direct |
Kelch motif | 0 | Direct |
Formin homology 2 domain (FH2 domain) | 0 | Direct |
SAICAR synthase-like | 0 | Direct |
MFS general substrate transporter | 0 | Direct |
t-snare proteins | 0 | Direct |
DNA-binding domain | 0 | Direct |
PreATP-grasp domain | 0 | Direct |
Toll/Interleukin receptor TIR domain | 0 | Direct |
(Trans)glycosidases | 0 | Direct |
R3H domain | 0 | Direct |
Glutathione synthetase ATP-binding domain-like | 0 | Direct |
Ypt/Rab-GAP domain of gyp1p | 0 | Direct |
FKBP-like | 0 | Direct |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
PAP/OAS1 substrate-binding domain | 0 | Direct |
Metallo-dependent phosphatases | 0 | Direct |
YWTD domain | 0 | Direct |
Ribonuclease H-like | 0 | Direct |
CAD & PB1 domains | 0 | Direct |
SAM/Pointed domain | 0 | Direct |
beta-sandwich domain of Sec23/24 | 0 | Direct |
TPR-like | 0 | Direct |
Actin depolymerizing proteins | 0 | Direct |
Ran binding protein zinc finger-like | 0 | Direct |
lambda repressor-like DNA-binding domains | 0 | Direct |
N-acetylmuramoyl-L-alanine amidase-like | 0 | Direct |
C-type lectin-like | 0 | Direct |
Mob1/phocein | 0 | Direct |
Second domain of FERM | 0 | Direct |
Class I glutamine amidotransferase-like | 0 | Direct |
Integrin domains | 0 | Direct |
HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
WW domain | 0 | Direct |
SAND domain-like | 0 | Direct |
RNI-like | 0 | Direct |
Protein kinase-like (PK-like) | 0.002069 | Inherited |
beta-beta-alpha zinc fingers | 0.006165 | Inherited |
Homeodomain-like | 0.07567 | Inherited |
P-loop containing nucleoside triphosphate hydrolases | 0.1721 | Inherited |
PH domain-like | 0.1981 | Inherited |
RING/U-box | 0.4076 | Inherited |
Fibronectin type III | 0.4358 | Inherited |
Ankyrin repeat | 0.5199 | Inherited |
E set domains | 0.5884 | Inherited |
Cyclin-like | 0.6077 | Inherited |
SH2 domain | 0.6166 | Inherited |
POZ domain | 0.6514 | Inherited |
Calponin-homology domain, CH-domain | 0.7411 | Inherited |
Cysteine-rich domain | 0.7411 | Inherited |
Cystine-knot cytokines | 0.7411 | Inherited |
Tubulin nucleotide-binding domain-like | 0.7679 | Inherited |
Invertebrate chitin-binding proteins | 0.7981 | Inherited |
Cytochrome P450 | 0.8134 | Inherited |
LDL receptor-like module | 0.8134 | Inherited |
CoA-dependent acyltransferases | 0.8302 | Inherited |
SET domain | 0.8323 | Inherited |
Spectrin repeat | 0.8513 | Inherited |
ENTH/VHS domain | 0.892 | Inherited |
Leucine zipper domain | 0.9384 | Inherited |
Metalloproteases ("zincins"), catalytic domain | 0.9433 | Inherited |
Immunoglobulin | 0.9875 | Inherited |
(show details)
Supra-domains annotated to this FA term (Not in SPFA)
Highlighted in gray are those with FDR>0.001
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57716,46689 57716 - Glucocorticoid receptor-like (DNA-binding domain) 46689 - Homeodomain-like | 0 | DIRECT |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | DIRECT |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | DIRECT |
47769,47769 47769 - SAM/Pointed domain 47769 - SAM/Pointed domain | 0 | DIRECT |
57903,47370 57903 - FYVE/PHD zinc finger 47370 - Bromodomain | 0 | DIRECT |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
52799,52799 52799 - (Phosphotyrosine protein) phosphatases II 52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
52058,48726 52058 - L domain-like 48726 - Immunoglobulin | 0 | DIRECT |
101690,53098 101690 - PAZ domain 53098 - Ribonuclease H-like | 0 | DIRECT |
56645,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | DIRECT |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | DIRECT |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0 | DIRECT |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0 | DIRECT |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | DIRECT |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | DIRECT |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | DIRECT |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | DIRECT |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | DIRECT |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | DIRECT |
55753,55753 55753 - Actin depolymerizing proteins 55753 - Actin depolymerizing proteins | 0 | DIRECT |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | DIRECT |
47220,47220 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like | 0 | DIRECT |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53223,51735 53223 - Aminoacid dehydrogenase-like, N-terminal domain 51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
51735,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | DIRECT |
81301,81631 81301 - Nucleotidyltransferase 81631 - PAP/OAS1 substrate-binding domain | 0 | DIRECT |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | DIRECT |
57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54534,48452 54534 - FKBP-like 48452 - TPR-like | 0 | DIRECT |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 0 | DIRECT |
47459,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | DIRECT |
47459,158457 47459 - HLH, helix-loop-helix DNA-binding domain 158457 - Orange domain-like | 0 | DIRECT |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0 | DIRECT |
49854,49854 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
55945,55945 55945 - TATA-box binding protein-like 55945 - TATA-box binding protein-like | 0 | DIRECT |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | DIRECT |
52113,52113 52113 - BRCT domain 52113 - BRCT domain | 0 | DIRECT |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | DIRECT |
75632,46785 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
63748,63748 63748 - Tudor/PWWP/MBT 63748 - Tudor/PWWP/MBT | 0 | DIRECT |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | DIRECT |
74788,75632 74788 - Cullin repeat-like 75632 - Cullin homology domain | 0 | DIRECT |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | DIRECT |
48452,48452 48452 - TPR-like 48452 - TPR-like | 0 | DIRECT |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | DIRECT |
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | DIRECT |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | DIRECT |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0 | DIRECT |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | DIRECT |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
81296,81296 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | DIRECT |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | DIRECT |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | DIRECT |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | DIRECT |
52540,48019 52540 - P-loop containing nucleoside triphosphate hydrolases 48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | DIRECT |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | DIRECT |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0 | DIRECT |
57196,49854 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | DIRECT |
54768,54768 54768 - dsRNA-binding domain-like 54768 - dsRNA-binding domain-like | 0 | DIRECT |
81383,52047 81383 - F-box domain 52047 - RNI-like | 0 | DIRECT |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | DIRECT |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
51206,51206 51206 - cAMP-binding domain-like 51206 - cAMP-binding domain-like | 0 | DIRECT |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0.03185 | INHERITED FROM: organ system || thoracic segment || adult segment || tagma || adult mesothoracic segment || adult || integumentary system || adult tagma || embryonic ganglion mother cell || adult thoracic segment || prescutum || adult integumentary system || postalar bristle || region of integument || thorax || adult thorax || appendage |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.6607 | INHERITED FROM: commissure || pacemaker neuron || neuropil glial sheath || chemosensory neuron || neuron projection bundle of ventral nerve cord || giant fiber neuron || adult antennal lobe glomerulus || tract neuropil || ganglionic branch primordium || s-LNv neuron || adult antennal lobe || embryonic heart cardioblast || mechanosensory neuron || gustatory receptor neuron || embryonic/larval thoracic/abdominal lateral sensory cluster || adult pacemaker neuron || LNv neuron || chemosensory system neuron || connective || lobe system of adult mushroom body || antennal lobe glomerulus || neuropil associated CNS glial cell || adult descending neuron || LN period neuron || neuron projection bundle || leg taste bristle chemosensory neuron |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0.6834 | INHERITED FROM: morphogenetic furrow |
47473,47473 47473 - EF-hand 47473 - EF-hand | 0.892 | INHERITED FROM: bouton |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 1 | INHERITED FROM: commissure || pacemaker neuron || adult cerebral ganglion || neuropil glial sheath || central nervous system || ganglion || embryonic somatic muscle || larval abdomen || adult head segment || tract neuropil || s-LNv neuron || synaptic neuropil || embryonic heart cardioblast || head segment || adult brain || adult pacemaker neuron || LNv neuron || embryonic cardioblast || longitudinal muscle || connective || lobe system of adult mushroom body || nervous system || antennal lobe glomerulus || LN period neuron || synaptic neuropil block || neuron projection bundle || leg taste bristle chemosensory neuron || dorsal vessel primordium || procephalic segment |
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57716,46689 57716 - Glucocorticoid receptor-like (DNA-binding domain) 46689 - Homeodomain-like | 0 | Direct |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | Direct |
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
52540,140990 52540 - P-loop containing nucleoside triphosphate hydrolases 140990 - FtsH protease domain-like | 0 | Direct |
47769,47769 47769 - SAM/Pointed domain 47769 - SAM/Pointed domain | 0 | Direct |
57903,47370 57903 - FYVE/PHD zinc finger 47370 - Bromodomain | 0 | Direct |
46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
52799,52799 52799 - (Phosphotyrosine protein) phosphatases II 52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
52058,48726 52058 - L domain-like 48726 - Immunoglobulin | 0 | Direct |
101690,53098 101690 - PAZ domain 53098 - Ribonuclease H-like | 0 | Direct |
56645,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
49562,49562 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0 | Direct |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | Direct |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0 | Direct |
48403,48403 48403 - Ankyrin repeat 48403 - Ankyrin repeat | 0 | Direct |
50044,52540 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like) | 0 | Direct |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0 | Direct |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | Direct |
52777,52777 52777 - CoA-dependent acyltransferases 52777 - CoA-dependent acyltransferases | 0 | Direct |
57889,57889 57889 - Cysteine-rich domain 57889 - Cysteine-rich domain | 0 | Direct |
50447,50465 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
100920,100934 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
49265,48726 49265 - Fibronectin type III 48726 - Immunoglobulin | 0 | Direct |
48592,54849 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like | 0 | Direct |
55753,55753 55753 - Actin depolymerizing proteins 55753 - Actin depolymerizing proteins | 0 | Direct |
57903,57903 57903 - FYVE/PHD zinc finger 57903 - FYVE/PHD zinc finger | 0 | Direct |
47220,47220 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like | 0 | Direct |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53223,51735 53223 - Aminoacid dehydrogenase-like, N-terminal domain 51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
53067,100920 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
51735,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like | 0 | Direct |
81301,81631 81301 - Nucleotidyltransferase 81631 - PAP/OAS1 substrate-binding domain | 0 | Direct |
50156,50044 50156 - PDZ domain-like 50044 - SH3-domain | 0 | Direct |
57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | Direct |
48371,56112 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
54534,48452 54534 - FKBP-like 48452 - TPR-like | 0 | Direct |
54849,52029 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin | 0 | Direct |
47459,55785 47459 - HLH, helix-loop-helix DNA-binding domain 55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0 | Direct |
47459,158457 47459 - HLH, helix-loop-helix DNA-binding domain 158457 - Orange domain-like | 0 | Direct |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0 | Direct |
49854,49854 49854 - Spermadhesin, CUB domain 49854 - Spermadhesin, CUB domain | 0 | Direct |
55945,55945 55945 - TATA-box binding protein-like 55945 - TATA-box binding protein-like | 0 | Direct |
48065,50729 48065 - DBL homology domain (DH-domain) 50729 - PH domain-like | 0 | Direct |
52113,52113 52113 - BRCT domain 52113 - BRCT domain | 0 | Direct |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | Direct |
75632,46785 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
63748,63748 63748 - Tudor/PWWP/MBT 63748 - Tudor/PWWP/MBT | 0 | Direct |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0 | Direct |
74788,75632 74788 - Cullin repeat-like 75632 - Cullin homology domain | 0 | Direct |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0 | Direct |
48452,48452 48452 - TPR-like 48452 - TPR-like | 0 | Direct |
82895,82895 82895 - TSP-1 type 1 repeat 82895 - TSP-1 type 1 repeat | 0 | Direct |
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
50044,50044 50044 - SH3-domain 50044 - SH3-domain | 0 | Direct |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
57184,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | Direct |
50044,55550 50044 - SH3-domain 55550 - SH2 domain | 0 | Direct |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49562,48371 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat | 0 | Direct |
52374,47323 52374 - Nucleotidylyl transferase 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
81296,81296 81296 - E set domains 81296 - E set domains | 0 | Direct |
50156,50156 50156 - PDZ domain-like 50156 - PDZ domain-like | 0 | Direct |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0 | Direct |
46785,46785 46785 - "Winged helix" DNA-binding domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
54791,54791 54791 - Eukaryotic type KH-domain (KH-domain type I) 54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0 | Direct |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | Direct |
52540,48019 52540 - P-loop containing nucleoside triphosphate hydrolases 48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
47031,50729 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
48425,50729 48425 - Sec7 domain 50729 - PH domain-like | 0 | Direct |
52490,55307 52490 - Tubulin nucleotide-binding domain-like 55307 - Tubulin C-terminal domain-like | 0 | Direct |
52440,56059 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
57716,48508 57716 - Glucocorticoid receptor-like (DNA-binding domain) 48508 - Nuclear receptor ligand-binding domain | 0 | Direct |
57196,49854 57196 - EGF/Laminin 49854 - Spermadhesin, CUB domain | 0 | Direct |
54768,54768 54768 - dsRNA-binding domain-like 54768 - dsRNA-binding domain-like | 0 | Direct |
81383,52047 81383 - F-box domain 52047 - RNI-like | 0 | Direct |
54236,54236 54236 - Ubiquitin-like 54236 - Ubiquitin-like | 0 | Direct |
57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
51206,51206 51206 - cAMP-binding domain-like 51206 - cAMP-binding domain-like | 0 | Direct |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0.03185 | Inherited |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.6607 | Inherited |
47954,47954 47954 - Cyclin-like 47954 - Cyclin-like | 0.6834 | Inherited |
47473,47473 47473 - EF-hand 47473 - EF-hand | 0.892 | Inherited |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 1 | Inherited |
(show details)
Supra-domains annotated to this FA term (Not in SPFA)
Highlighted in gray are those with FDR>0.001
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
49265,48726,48726 49265 - Fibronectin type III 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | DIRECT |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | DIRECT |
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | DIRECT |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
74788,75632,46785 74788 - Cullin repeat-like 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | DIRECT |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | DIRECT |
57667,57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | DIRECT |
57625,57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
57184,57196,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | DIRECT |
52058,52058,52058 52058 - L domain-like 52058 - L domain-like 52058 - L domain-like | 0 | DIRECT |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | DIRECT |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | DIRECT |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | DIRECT |
57196,57184,57196 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | DIRECT |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | DIRECT |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | DIRECT |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | DIRECT |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.7078 | INHERITED FROM: pacemaker neuron || embryonic/larval central nervous system || neuropil glial sheath || chemosensory neuron || eo neuron || neuron projection bundle of ventral nerve cord || giant fiber neuron || adult antennal lobe glomerulus || ganglionic branch primordium || s-LNv neuron || adult antennal lobe || embryonic heart cardioblast || mechanosensory system neuron || mechanosensory neuron || gustatory receptor neuron || embryonic/larval thoracic/abdominal lateral sensory cluster || adult pacemaker neuron || LNv neuron || chemosensory system neuron || connective || lobe system of adult mushroom body || antennal lobe glomerulus || neuropil associated CNS glial cell || adult descending neuron || LN period neuron || neuron projection bundle || leg taste bristle chemosensory neuron |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 1 | INHERITED FROM: commissure || pacemaker neuron || central nervous system || neuron projection bundle of ventral nerve cord || tract neuropil || s-LNv neuron || synaptic neuropil || interneuron || embryonic heart cardioblast || head segment || adult brain || gustatory receptor neuron || adult pacemaker neuron || LNv neuron || embryonic cardioblast || connective || lobe system of adult mushroom body || embryonic/larval garland cell || synaptic neuropil block || neuron projection bundle || leg taste bristle chemosensory neuron || embryonic/larval garland organ || procephalic segment |
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,53067,100920 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
49265,48726,48726 49265 - Fibronectin type III 48726 - Immunoglobulin 48726 - Immunoglobulin | 0 | Direct |
49562,48371,56112 49562 - C2 domain (Calcium/lipid-binding domain, CaLB) 48371 - ARM repeat 56112 - Protein kinase-like (PK-like) | 0 | Direct |
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
57535,57535,57535 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain 57535 - Complement control module/SCR domain | 0 | Direct |
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0 | Direct |
57716,57716,57716 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) 57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
74788,75632,46785 74788 - Cullin repeat-like 75632 - Cullin homology domain 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0 | Direct |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
48592,54849,52029 48592 - GroEL equatorial domain-like 54849 - GroEL-intermediate domain like 52029 - GroEL apical domain-like | 0 | Direct |
57667,57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0 | Direct |
57625,57625,57625 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins 57625 - Invertebrate chitin-binding proteins | 0 | Direct |
57184,57196,57196 57184 - Growth factor receptor domain 57196 - EGF/Laminin 57196 - EGF/Laminin | 0 | Direct |
52058,52058,52058 52058 - L domain-like 52058 - L domain-like 52058 - L domain-like | 0 | Direct |
57424,57424,57424 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57424 - LDL receptor-like module | 0 | Direct |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0 | Direct |
81296,81296,81296 81296 - E set domains 81296 - E set domains 81296 - E set domains | 0 | Direct |
57196,57184,57196 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57196 - EGF/Laminin | 0 | Direct |
52540,50447,50465 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 0 | Direct |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0 | Direct |
49899,49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53067,100920,100934 53067 - Actin-like ATPase domain 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
48452,48452,48452 48452 - TPR-like 48452 - TPR-like 48452 - TPR-like | 0 | Direct |
50156,50044,52540 50156 - PDZ domain-like 50044 - SH3-domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.7078 | Inherited |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 1 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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A presence/absence matrix is generated using protein domains and supradomains
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heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
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