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Fly Anatomy (FA): larva
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: FA Hierarchy (fly anatomy from FlyBase anatomy ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this FA term (SDFA level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
| RNase III catalytic domain-like | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| Nucleosome core histones | 0 | DIRECT |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | DIRECT |
| MBT repeat | 0 | DIRECT |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
| Hect, E3 ligase catalytic domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| R3H domain | 0 | DIRECT |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| SCF ubiquitin ligase complex WHB domain | 0 | DIRECT |
| Fibroblast growth factors (FGF) | 0 | DIRECT |
| SNARE fusion complex | 0 | DIRECT |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
| Thioltransferase | 0 | DIRECT |
| Frizzled cysteine-rich domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Cullin homology domain | 0 | DIRECT |
| SPRY domain | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | DIRECT |
| Toll/Interleukin receptor TIR domain | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| Class II glutamine amidotransferases | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| Regulator of chromosome condensation RCC1 | 0 | DIRECT |
| Diacylglycerol kinase-like | 0 | DIRECT |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | DIRECT |
| Diap1 N-terninal region-like | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
| Extracellular domain of cell surface receptors | 0 | DIRECT |
| Histone deacetylase, HDAC | 0 | DIRECT |
| Transforming growth factor (TGF)-beta | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| EF-hand modules in multidomain proteins | 0 | DIRECT |
| Laminin-type module | 0 | DIRECT |
| POU-specific domain | 0 | DIRECT |
| Tetramerization domain of potassium channels | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| L-arabinose binding protein-like | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| CRAL/TRIO domain | 0 | DIRECT |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| Cullin repeat | 0 | DIRECT |
| acyl-CoA oxidase C-terminal domains | 0 | DIRECT |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Arrestin/Vps26-like | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| acyl-CoA oxidase N-terminal domains | 0 | DIRECT |
| MIR domain | 0 | DIRECT |
| Protein kinases, catalytic subunit | 0.04479 | INHERITED FROM: photoreceptor cell R8 of pale ommatidium || imaginal disc || larval imaginal tissue || embryonic/larval integumentary system |
| Homeodomain | 0.06964 | INHERITED FROM: embryonic supraesophageal neuromere || larval neuromere || larval segment || maxillary palp olfactory receptor neuron || transverse nerve || ventral intersegmental muscle || larval prothoracic segment || embryonic/larval sensillum || hypodermal muscle of prothorax || embryonic/larval subesophageal ganglion || dorsal margin photoreceptor || larval tagma || interneuron || EL neuron || larval head || embryonic/larval sense organ || A1-7 ventral acute muscle 1 || T1 beard || embryonic/larval supraesophageal ganglion || larval metathoracic segment || larval abdomen || larval head segment || embryonic/larval neuron || uniglomerular antennal lobe projection neuron || embryonic/larval central nervous system || embryonic/larval labial organ || U neuron || metathoracic ventral denticle belt || prothoracic ventral intersegmental muscle || terminal organ || embryonic/larval muscle system |
| Laminin G-like module | 0.1027 | INHERITED FROM: rhabdomeric photoreceptor cell || embryonic/larval dorsal vessel || photoreceptor cell R4 |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.1027 | INHERITED FROM: embryonic/larval garland cell || embryonic/larval garland organ |
| Spectrin repeat | 0.112 | INHERITED FROM: embryonic/larval gut || embryonic/larval alimentary canal || longitudinal connective || neuron projection bundle of ventral nerve cord |
| Paired domain | 0.1261 | INHERITED FROM: RP2 motor neuron || abdominal 2 ventral denticle belt || EG neuron || abdominal 8 ventral denticle belt || abdominal 4 ventral denticle belt || EL neuron || abdominal 6 ventral denticle belt || abdominal ventral denticle belt || larval abdominal segment A2-7 || U neuron |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0.1261 | INHERITED FROM: intersegmental nerve |
| Growth factor receptor domain | 0.1261 | INHERITED FROM: embryonic/larval tracheal system || primary lobe of embryonic/larval lymph gland || embryonic/larval lymph gland |
| Proteasome subunits | 0.1261 | INHERITED FROM: embryonic/larval fat body |
| Fibronectin type III | 0.1548 | INHERITED FROM: LNv neuron || larval tagma || LN period neuron || pacemaker neuron || larval abdomen || s-LNv neuron || adult pacemaker neuron || gustatory receptor neuron || neuron projection bundle of ventral nerve cord |
| G proteins | 0.1812 | INHERITED FROM: embryonic/larval fat body || embryonic/larval adipose system |
| LDL receptor-like module | 0.2338 | INHERITED FROM: embryonic/larval dorsal trunk |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0.2343 | INHERITED FROM: eye-antennal disc || eye disc || gastric caecum |
| T-box | 0.2343 | INHERITED FROM: embryonic/larval dorsal vessel |
| EGF-type module | 0.2405 | INHERITED FROM: embryonic/larval midgut cell || adult midgut progenitor cell || embryonic/larval tracheal system || primary lobe of embryonic/larval lymph gland || cortical zone of lymph gland primary lobe || dorsal acute muscle |
| I set domains | 0.274 | INHERITED FROM: interface glial cell || LNv neuron || embryonic/larval lateral glial cell || mechanosensory system neuron || gustatory system neuron || pacemaker neuron || adult descending neuron || larval abdomen || s-LNv neuron || larval abdominal sensory neuron || adult pacemaker neuron || gustatory receptor neuron || leg taste bristle chemosensory neuron || embryonic/larval thoracic/abdominal lateral sensory cluster |
| Ngr ectodomain-like | 0.3644 | INHERITED FROM: intersegmental nerve branch ISNb of A1-7 || abdominal intersegmental nerve || intersegmental nerve of A1-7 |
| Cap-Gly domain | 0.4387 | INHERITED FROM: interneuron |
| SH2 domain | 0.4537 | INHERITED FROM: rhabdomeric photoreceptor cell || photoreceptor cell || adult optic lobe neuron || histaminergic neuron || photoreceptor cell R7 |
| Histone lysine methyltransferases | 0.4927 | INHERITED FROM: dorsal thoracic disc |
| Ankyrin repeat | 0.5126 | INHERITED FROM: ventral multidendritic neuron || Johnston organ neuron |
| Forkhead DNA-binding domain | 0.518 | INHERITED FROM: RP2sib neuron || embryonic/larval digestive system |
| Caspase catalytic domain | 0.6524 | INHERITED FROM: peptidergic neuron |
| Regulator of G-protein signaling, RGS | 0.6524 | INHERITED FROM: embryonic/first instar larval cuticle |
| Calponin-homology domain, CH-domain | 0.6815 | INHERITED FROM: abdominal segmental nerve |
| HLH, helix-loop-helix DNA-binding domain | 0.7054 | INHERITED FROM: EL neuron || 5-6I of thorax |
| Hairy Orange domain | 0.7131 | INHERITED FROM: EG neuron || EL neuron |
| Cytochrome P450 | 0.7207 | INHERITED FROM: midline glial cell || embryonic/larval glial cell || larval neuropil glial cell || larval VNC neuropil glial cell || embryonic/larval hindgut || embryonic/larval foregut |
| Ubiquitin-related | 0.7207 | INHERITED FROM: mushroom body extrinsic neuron |
| Nuclear receptor ligand-binding domain | 0.7436 | INHERITED FROM: mushroom body intrinsic neuron || interneuron || supraesophageal ganglion neuron |
| Nuclear receptor | 0.778 | INHERITED FROM: mushroom body intrinsic neuron || interneuron || supraesophageal ganglion neuron || larval abdominal neuromere |
| Cadherin | 0.7827 | INHERITED FROM: outer photoreceptor cell || photoreceptor cell R4 |
| Classic zinc finger, C2H2 | 1 | INHERITED FROM: embryonic/larval head sensillum |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
| RNase III catalytic domain-like | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| FHA domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| Nucleosome core histones | 0 | Direct |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | Direct |
| MBT repeat | 0 | Direct |
| DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
| Hect, E3 ligase catalytic domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| R3H domain | 0 | Direct |
| DNA polymerase III clamp loader subunits, C-terminal domain | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| SCF ubiquitin ligase complex WHB domain | 0 | Direct |
| Fibroblast growth factors (FGF) | 0 | Direct |
| SNARE fusion complex | 0 | Direct |
| Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
| Thioltransferase | 0 | Direct |
| Frizzled cysteine-rich domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Cullin homology domain | 0 | Direct |
| SPRY domain | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| Tropomyosin | 0 | Direct |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0 | Direct |
| Toll/Interleukin receptor TIR domain | 0 | Direct |
| SMAD domain | 0 | Direct |
| Class II glutamine amidotransferases | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| Regulator of chromosome condensation RCC1 | 0 | Direct |
| Diacylglycerol kinase-like | 0 | Direct |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | Direct |
| Diap1 N-terninal region-like | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
| Extracellular domain of cell surface receptors | 0 | Direct |
| Histone deacetylase, HDAC | 0 | Direct |
| Transforming growth factor (TGF)-beta | 0 | Direct |
| Sema domain | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| L27 domain | 0 | Direct |
| EF-hand modules in multidomain proteins | 0 | Direct |
| Laminin-type module | 0 | Direct |
| POU-specific domain | 0 | Direct |
| Tetramerization domain of potassium channels | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| SAP domain | 0 | Direct |
| L-arabinose binding protein-like | 0 | Direct |
| Integrin domains | 0 | Direct |
| CRAL/TRIO domain | 0 | Direct |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
| Zf-UBP | 0 | Direct |
| Cullin repeat | 0 | Direct |
| acyl-CoA oxidase C-terminal domains | 0 | Direct |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Arrestin/Vps26-like | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| acyl-CoA oxidase N-terminal domains | 0 | Direct |
| MIR domain | 0 | Direct |
| Protein kinases, catalytic subunit | 0.04479 | Inherited |
| Homeodomain | 0.06964 | Inherited |
| Laminin G-like module | 0.1027 | Inherited |
| FYVE, a phosphatidylinositol-3-phosphate binding domain | 0.1027 | Inherited |
| Spectrin repeat | 0.112 | Inherited |
| Paired domain | 0.1261 | Inherited |
| Higher-molecular-weight phosphotyrosine protein phosphatases | 0.1261 | Inherited |
| Growth factor receptor domain | 0.1261 | Inherited |
| Proteasome subunits | 0.1261 | Inherited |
| Fibronectin type III | 0.1548 | Inherited |
| G proteins | 0.1812 | Inherited |
| LDL receptor-like module | 0.2338 | Inherited |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0.2343 | Inherited |
| T-box | 0.2343 | Inherited |
| EGF-type module | 0.2405 | Inherited |
| I set domains | 0.274 | Inherited |
| Ngr ectodomain-like | 0.3644 | Inherited |
| Cap-Gly domain | 0.4387 | Inherited |
| SH2 domain | 0.4537 | Inherited |
| Histone lysine methyltransferases | 0.4927 | Inherited |
| Ankyrin repeat | 0.5126 | Inherited |
| Forkhead DNA-binding domain | 0.518 | Inherited |
| Caspase catalytic domain | 0.6524 | Inherited |
| Regulator of G-protein signaling, RGS | 0.6524 | Inherited |
| Calponin-homology domain, CH-domain | 0.6815 | Inherited |
| HLH, helix-loop-helix DNA-binding domain | 0.7054 | Inherited |
| Hairy Orange domain | 0.7131 | Inherited |
| Cytochrome P450 | 0.7207 | Inherited |
| Ubiquitin-related | 0.7207 | Inherited |
| Nuclear receptor ligand-binding domain | 0.7436 | Inherited |
| Nuclear receptor | 0.778 | Inherited |
| Cadherin | 0.7827 | Inherited |
| Classic zinc finger, C2H2 | 1 | Inherited |
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
 |
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Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
(show details)
Supra-domains annotated to this FA term (SPFA level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | DIRECT |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | DIRECT |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0 | DIRECT |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
49854,49854
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | DIRECT |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | DIRECT |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | DIRECT |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0.2221 | INHERITED FROM: embryonic/larval tracheal system |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.2681 | INHERITED FROM: pacemaker neuron || adult pacemaker neuron || LNv neuron || larval abdomen || longitudinal muscle || s-LNv neuron || LN period neuron || leg taste bristle chemosensory neuron |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.2751 | INHERITED FROM: photoreceptor cell R7 || embryonic/larval tracheal system || cortical zone of lymph gland primary lobe || embryonic/larval lymph gland || primary lobe of embryonic/larval lymph gland || embryonic/larval dorsal branch || inner photoreceptor cell || crystal cell || intersegmental nerve |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.4006 | INHERITED FROM: embryonic/larval pericardial cell || rhabdomeric photoreceptor cell || embryonic/larval somatic muscle || intersegmental nerve branch ISNb of A1-7 || eye disc posterior to the morphogenetic furrow || embryonic/larval muscle system || eye photoreceptor cell stalk || embryonic/larval dorsal vessel |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.4041 | INHERITED FROM: mechanosensory system neuron || mechanosensory neuron |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.4273 | INHERITED FROM: bouton || synapse |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0.4273 | INHERITED FROM: embryonic/larval peripheral nervous system |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.4273 | INHERITED FROM: photoreceptor cell R7 || inner photoreceptor cell |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.45 | INHERITED FROM: imaginal disc posterior compartment || dorsal thoracic disc posterior compartment || wing disc posterior compartment |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.5503 | INHERITED FROM: abdominal neuron || larval abdominal sensory neuron || dendritic arborizing neuron || larval abdomen || multidendritic neuron || intersegmental nerve |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.5573 | INHERITED FROM: pacemaker neuron || gustatory receptor neuron || mechanosensory neuron || adult pacemaker neuron || LNv neuron || embryonic/larval thoracic/abdominal lateral sensory cluster || chemosensory neuron || giant fiber neuron || neuron projection bundle of ventral nerve cord || chemosensory system neuron || adult descending neuron || s-LNv neuron || LN period neuron || leg taste bristle chemosensory neuron |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0.6239 | INHERITED FROM: 5-6I of thorax || 5-6I || nervous system of embryonic/larval thorax || EL neuron || EG neuron || thoracic neuron |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.7643 | INHERITED FROM: bouton |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.7653 | INHERITED FROM: photoreceptor cell R4 || outer photoreceptor cell |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.8855 | INHERITED FROM: morphogenetic furrow |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
47769,47769
47769 - SAM/Pointed domain
47769 - SAM/Pointed domain | 0 | Direct |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
52799,52799
52799 - (Phosphotyrosine protein) phosphatases II
52799 - (Phosphotyrosine protein) phosphatases II | 0 | Direct |
56645,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0 | Direct |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
49854,49854
49854 - Spermadhesin, CUB domain
49854 - Spermadhesin, CUB domain | 0 | Direct |
75632,46785
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | Direct |
74788,75632
74788 - Cullin repeat-like
75632 - Cullin homology domain | 0 | Direct |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
48452,48452
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
47203,47203
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
81660,56784
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
81296,81296
81296 - E set domains
81296 - E set domains | 0 | Direct |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
51045,51045
51045 - WW domain
51045 - WW domain | 0 | Direct |
52540,48019
52540 - P-loop containing nucleoside triphosphate hydrolases
48019 - post-AAA+ oligomerization domain-like | 0 | Direct |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0.2221 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.2681 | Inherited |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.2751 | Inherited |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.4006 | Inherited |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0.4041 | Inherited |
49562,49562
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
49562 - C2 domain (Calcium/lipid-binding domain, CaLB) | 0.4273 | Inherited |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0.4273 | Inherited |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0.4273 | Inherited |
54928,54928
54928 - RNA-binding domain, RBD
54928 - RNA-binding domain, RBD | 0.45 | Inherited |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0.5503 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.5573 | Inherited |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0.6239 | Inherited |
47473,47473
47473 - EF-hand
47473 - EF-hand | 0.7643 | Inherited |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.7653 | Inherited |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0.8855 | Inherited |
(show details)
Supra-domains annotated to this FA term (SPFA level: Least Informative)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | DIRECT |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | DIRECT |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | DIRECT |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.07447 | INHERITED FROM: embryonic/larval pericardial cell || rhabdomeric photoreceptor cell || embryonic/larval circulatory system || adult optic lobe neuron || embryonic/larval somatic muscle || embryonic/larval tracheal system || embryonic/larval hypodermal muscle || sensory neuron || embryonic/larval digestive system || eye disc posterior to the morphogenetic furrow || eye photoreceptor cell stalk || primary lobe of embryonic/larval lymph gland || histaminergic neuron || larval segment || larval tagma || embryonic/larval dorsal vessel || photoreceptor cell R6 || photoreceptor cell R1 |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.3428 | INHERITED FROM: embryonic/larval tracheal system || embryonic/larval trachea |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.5293 | INHERITED FROM: embryonic/larval central nervous system || mechanosensory system neuron || pacemaker neuron || gustatory receptor neuron || mechanosensory neuron || adult pacemaker neuron || LNv neuron || embryonic/larval thoracic/abdominal lateral sensory cluster || chemosensory neuron || giant fiber neuron || neuron projection bundle of ventral nerve cord || eo neuron || chemosensory system neuron || adult descending neuron || s-LNv neuron || LN period neuron || leg taste bristle chemosensory neuron |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.5511 | INHERITED FROM: pacemaker neuron || gustatory receptor neuron || adult pacemaker neuron || LNv neuron || neuron projection bundle of ventral nerve cord || embryonic/larval garland cell || s-LNv neuron || interneuron || leg taste bristle chemosensory neuron || embryonic/larval garland organ |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.7653 | INHERITED FROM: photoreceptor cell R4 || outer photoreceptor cell |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
56645,47203,47203
56645 - Acyl-CoA dehydrogenase NM domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like
47203 - Acyl-CoA dehydrogenase C-terminal domain-like | 0 | Direct |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
57716,57716,57716
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57716 - Glucocorticoid receptor-like (DNA-binding domain) | 0 | Direct |
74788,75632,46785
74788 - Cullin repeat-like
75632 - Cullin homology domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
81660,56784,81665
81660 - Metal cation-transporting ATPase, ATP-binding domain N
56784 - HAD-like
81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0 | Direct |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
57196,57196,57184
57196 - EGF/Laminin
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.07447 | Inherited |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.3428 | Inherited |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.5293 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.5511 | Inherited |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.7653 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
|
Plot tree as:
| |
Download Newick format tree:
|
(show help)
Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
|
