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Fly Anatomy (FA): sensory system
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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
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Root: FA Hierarchy (fly anatomy from FlyBase anatomy ontology)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this FA term (Not in SDFA)
Highlighted in gray are those with FDR_all>0.001
SCOP term | FDR (all) | Annotation (direct or inherited) |
RNase III catalytic domain-like | 0 | DIRECT |
Eps15 homology domain (EH domain) | 0 | DIRECT |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
Fibrinogen C-terminal domain-like | 0 | DIRECT |
Rel/Dorsal transcription factors, DNA-binding domain | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
Frizzled cysteine-rich domain | 0 | DIRECT |
VHS domain | 0 | DIRECT |
Diacylglycerol kinase-like | 0 | DIRECT |
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | DIRECT |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | DIRECT |
Sema domain | 0 | DIRECT |
Laminin-type module | 0 | DIRECT |
SAP domain | 0 | DIRECT |
Integrin domains | 0 | DIRECT |
Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
Arrestin/Vps26-like | 0 | DIRECT |
Third domain of FERM | 0.03637 | INHERITED FROM: ommatidium |
Laminin G-like module | 0.05323 | INHERITED FROM: photoreceptor cell R4 || rhabdomeric photoreceptor cell |
Second domain of FERM | 0.05323 | INHERITED FROM: head bristle |
POU-specific domain | 0.05913 | INHERITED FROM: adult olfactory receptor neuron Or42a || olfactory system || chemosensory system || olfactory system neuron || chemosensory neuron || chemosensory system neuron || olfactory receptor neuron || antennal sense organ || eo neuron || adult olfactory receptor neuron |
PLC-like (P variant) | 0.0599 | INHERITED FROM: larval dorsal multidendritic neuron || larval dorsal multidendritic neuron ddaC |
Growth factor receptor domain | 0.08202 | INHERITED FROM: ocellus |
I set domains | 0.1007 | INHERITED FROM: gustatory system || gustatory system neuron || leg taste bristle chemosensory neuron || mechanosensory system neuron || gustatory receptor neuron || larval abdominal sensory neuron |
SH2 domain | 0.1165 | INHERITED FROM: photoreceptor cell R7 || head sensillum || photoreceptor cell || ommatidium || rhabdomeric photoreceptor cell |
Fibronectin type III | 0.1191 | INHERITED FROM: gustatory receptor neuron |
Ankyrin repeat | 0.1223 | INHERITED FROM: ventral multidendritic neuron || Johnston organ neuron |
Cadherin | 0.1867 | INHERITED FROM: photoreceptor cell R4 || outer photoreceptor cell |
Protein kinases, catalytic subunit | 0.225 | INHERITED FROM: photoreceptor cell R8 of pale ommatidium |
Transducin (alpha subunit), insertion domain | 0.3899 | INHERITED FROM: chemosensory system || eo neuron |
Classic zinc finger, C2H2 | 0.6027 | INHERITED FROM: embryonic/larval head sensillum |
HLH, helix-loop-helix DNA-binding domain | 0.6396 | INHERITED FROM: sensillum campaniformium || anterior orbital bristle |
Homeodomain | 0.9144 | INHERITED FROM: terminal organ || head bristle || embryonic/larval sense organ || embryonic/larval labial organ || dorsal rim area || dorsal margin photoreceptor || embryonic/larval sensillum || maxillary palp olfactory receptor neuron || dorsal margin ommatidium |
SCOP term | FDR (all) | Annotation (direct or inherited) |
RNase III catalytic domain-like | 0 | Direct |
Eps15 homology domain (EH domain) | 0 | Direct |
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
Fibrinogen C-terminal domain-like | 0 | Direct |
Rel/Dorsal transcription factors, DNA-binding domain | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
Frizzled cysteine-rich domain | 0 | Direct |
VHS domain | 0 | Direct |
Diacylglycerol kinase-like | 0 | Direct |
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | Direct |
Inositol polyphosphate 5-phosphatase (IPP5) | 0 | Direct |
Sema domain | 0 | Direct |
Laminin-type module | 0 | Direct |
SAP domain | 0 | Direct |
Integrin domains | 0 | Direct |
Cell cycle control phosphatase, catalytic domain | 0 | Direct |
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
Arrestin/Vps26-like | 0 | Direct |
Third domain of FERM | 0.03637 | Inherited |
Laminin G-like module | 0.05323 | Inherited |
Second domain of FERM | 0.05323 | Inherited |
POU-specific domain | 0.05913 | Inherited |
PLC-like (P variant) | 0.0599 | Inherited |
Growth factor receptor domain | 0.08202 | Inherited |
I set domains | 0.1007 | Inherited |
SH2 domain | 0.1165 | Inherited |
Fibronectin type III | 0.1191 | Inherited |
Ankyrin repeat | 0.1223 | Inherited |
Cadherin | 0.1867 | Inherited |
Protein kinases, catalytic subunit | 0.225 | Inherited |
Transducin (alpha subunit), insertion domain | 0.3899 | Inherited |
Classic zinc finger, C2H2 | 0.6027 | Inherited |
HLH, helix-loop-helix DNA-binding domain | 0.6396 | Inherited |
Homeodomain | 0.9144 | Inherited |
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Trees by TreeVector
A presence/absence matrix is generated using protein domain
architecture data for all genomes in SUPERFAMILY. The PAUP
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this FA term (Not in SPFA)
Highlighted in gray are those with FDR>0.001
(show details)
Supra-domains annotated to this FA term (Not in SPFA)
Highlighted in gray are those with FDR>0.001
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | DIRECT |
57903,47370 57903 - FYVE/PHD zinc finger 47370 - Bromodomain | 0 | DIRECT |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0 | DIRECT |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | DIRECT |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | DIRECT |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | DIRECT |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.01318 | INHERITED FROM: leg taste bristle chemosensory neuron |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0.015 | INHERITED FROM: macrochaeta || mechanosensory system || mechanosensory sensory organ |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0.02801 | INHERITED FROM: olfactory receptor neuron || sensory neuron || chemosensory system || olfactory system neuron || antennal sense organ || adult olfactory receptor neuron || eo neuron || chemosensory sensory organ || adult olfactory receptor neuron Or42a || larval multidendritic class IV neuron |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0.02956 | INHERITED FROM: photoreceptor cell R4 || rhabdomeric photoreceptor cell || external compound sense organ || photoreceptor || compound sense organ |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0.04887 | INHERITED FROM: secondary pigment cell || ocellus || rhabdomeric photoreceptor cell || tertiary pigment cell || eye photoreceptor cell stalk |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0.09504 | INHERITED FROM: photoreceptor cell R7 || inner photoreceptor cell |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0.1069 | INHERITED FROM: head bristle |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.1159 | INHERITED FROM: mechanosensory neuron || gustatory receptor neuron || chemosensory system neuron || leg taste bristle chemosensory neuron || chemosensory neuron |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0.1383 | INHERITED FROM: mesothoracic bristle || adult thoracic sensillum || photoreceptor cell R7 || inner photoreceptor cell || adult mesothoracic sensillum || interommatidial bristle |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0.1525 | INHERITED FROM: bristle of mesothoracic tergum |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0.1647 | INHERITED FROM: photoreceptor cell R4 || outer photoreceptor cell |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0.2486 | INHERITED FROM: dendritic arborizing neuron || larval abdominal sensory neuron || multidendritic neuron |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.3633 | INHERITED FROM: chemosensory system || eo neuron |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0.489 | INHERITED FROM: mechanosensory neuron || mechanosensory system neuron |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0.9879 | INHERITED FROM: postalar bristle |
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
101912,103575 101912 - Sema domain 103575 - Plexin repeat | 0 | Direct |
57903,47370 57903 - FYVE/PHD zinc finger 47370 - Bromodomain | 0 | Direct |
49417,81296 49417 - p53-like transcription factors 81296 - E set domains | 0 | Direct |
57184,57184 57184 - Growth factor receptor domain 57184 - Growth factor receptor domain | 0 | Direct |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | Direct |
51045,51045 51045 - WW domain 51045 - WW domain | 0 | Direct |
48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.01318 | Inherited |
52058,52058 52058 - L domain-like 52058 - L domain-like | 0.015 | Inherited |
47413,46689 47413 - lambda repressor-like DNA-binding domains 46689 - Homeodomain-like | 0.02801 | Inherited |
49899,49899 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0.02956 | Inherited |
57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin | 0.04887 | Inherited |
55550,50044 55550 - SH2 domain 50044 - SH3-domain | 0.09504 | Inherited |
54236,47031 54236 - Ubiquitin-like 47031 - Second domain of FERM | 0.1069 | Inherited |
48726,49265 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.1159 | Inherited |
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0.1383 | Inherited |
54928,54928 54928 - RNA-binding domain, RBD 54928 - RNA-binding domain, RBD | 0.1525 | Inherited |
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like | 0.1647 | Inherited |
49265,49265 49265 - Fibronectin type III 49265 - Fibronectin type III | 0.2486 | Inherited |
47895,52540 47895 - Transducin (alpha subunit), insertion domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.3633 | Inherited |
50978,50978 50978 - WD40 repeat-like 50978 - WD40 repeat-like | 0.489 | Inherited |
57667,57667 57667 - beta-beta-alpha zinc fingers 57667 - beta-beta-alpha zinc fingers | 0.9879 | Inherited |
(show details)
Supra-domains annotated to this FA term (Not in SPFA)
Highlighted in gray are those with FDR>0.001
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0.0004735 | DIRECT |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0.02801 | INHERITED FROM: sensory system neuron || sensory neuron |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.04295 | INHERITED FROM: gustatory receptor neuron || leg taste bristle chemosensory neuron |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0.05203 | INHERITED FROM: bristle of mesothoracic tergum || adult thoracic mechanosensory chaeta |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.07143 | INHERITED FROM: mechanosensory neuron || gustatory receptor neuron || mechanosensory system neuron || chemosensory system neuron || eo neuron || leg taste bristle chemosensory neuron || chemosensory neuron |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0.08441 | INHERITED FROM: head bristle |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0.1647 | INHERITED FROM: photoreceptor cell R4 || outer photoreceptor cell |
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
57196,57196,57196 57196 - EGF/Laminin 57196 - EGF/Laminin 57196 - EGF/Laminin | 0.0004735 | Direct |
46966,46966,46966 46966 - Spectrin repeat 46966 - Spectrin repeat 46966 - Spectrin repeat | 0.02801 | Inherited |
48726,48726,48726 48726 - Immunoglobulin 48726 - Immunoglobulin 48726 - Immunoglobulin | 0.04295 | Inherited |
57196,57196,57184 57196 - EGF/Laminin 57196 - EGF/Laminin 57184 - Growth factor receptor domain | 0.05203 | Inherited |
48726,48726,49265 48726 - Immunoglobulin 48726 - Immunoglobulin 49265 - Fibronectin type III | 0.07143 | Inherited |
54236,47031,50729 54236 - Ubiquitin-like 47031 - Second domain of FERM 50729 - PH domain-like | 0.08441 | Inherited |
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like | 0.1647 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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