Fly Phenotype (FP): viable

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Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:

Disease Ontology (DO) Ontology (DO)
DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
Human Phenotype (HP) Ontology (HP)
HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
Mouse Phenotype (MP) Ontology (MP)
MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
Worm Phenotype (WP) Ontology (WP)
WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
Yeast Phenotype (YP) Ontology (YP)
Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
Fly Phenotype (FP) Ontology (FP)
FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
Fly Anatomy (FA) Ontology (FA)
FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
Zebrafish Anatomy (ZA) Ontology (ZA)
ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
Xenopus Anatomy (XA) Ontology (XA)
XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
Arabidopsis Plant Ontology (AP) Ontology (AP)
As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
Enzyme Commission (EC) Ontology (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
DrugBank ATC (DB) Ontology (DB)
In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
UniProtKB KeyWords (KW) Ontology (KW)
Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
UniProtKB UniPathway (UP) Ontology (UP)
UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.

Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations:
For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).

Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.

Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations:
For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).

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Root: FP Hierarchy (fly phenotype from FlyBase controlled vocabulary with sub-ontology "phenotypic class")

Shortest distance to current term (+ for parents, - for children) FP term [FP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)

+ 1: phenotypic class [FBcv:0000347] <4>

0: viable [FBcv:0000349] <1> (37|53) (37|23|10)

- 1: partially lethal - majority live [FBcv:0000350] (0|0) (0|0|0)

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Superfamily

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SCOP term	FDR (all)	Annotation (direct or inherited)
FMN-linked oxidoreductases	0	Direct
Integrin domains	0	Direct
Ribosomal proteins S24e, L23 and L15e	0	Direct
beta-N-acetylhexosaminidase-like domain	0	Direct
alpha-helical ferredoxin	0	Direct
Composite domain of metallo-dependent hydrolases	0	Direct
Regulator of G-protein signaling, RGS	0	Direct
Carboxypeptidase regulatory domain-like	0	Direct
Phospholipase A2, PLA2	0	Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	0	Direct
Nucleotide-binding domain	0	Direct
GAT-like domain	0	Direct
6-phosphogluconate dehydrogenase C-terminal domain-like	0	Direct
Acyl-CoA dehydrogenase NM domain-like	0	Direct
TIMP-like	0	Direct
HD-domain/PDEase-like	0	Direct
Acyl-CoA dehydrogenase C-terminal domain-like	0	Direct
Class I glutamine amidotransferase-like	0	Direct
Insulin-like	0	Direct
L27 domain	0	Direct
NAD(P)-linked oxidoreductase	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
NHL repeat	0	Direct
Seven-hairpin glycosidases	0	Direct
Integrin alpha N-terminal domain	0	Direct
Isocitrate/Isopropylmalate dehydrogenase-like	0	Direct
B-box zinc-binding domain	0	Direct
PapD-like	0	Direct
Chitinase insertion domain	0	Direct
alpha-catenin/vinculin-like	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Formin homology 2 domain (FH2 domain)	0	Direct
VPS9 domain	0	Direct
DPP6 N-terminal domain-like	0	Direct
E2F-DP heterodimerization region	0	Direct
FnI-like domain	0	Direct
HSP90 C-terminal domain	0	Direct

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Family

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SCOP term	FDR (all)	Annotation (direct or inherited)
MSP-like	0	Direct
Hsp90 middle domain	0	Direct
Insulin-like	0	Direct
Class I alpha-1;2-mannosidase, catalytic domain	0	Direct
FCH domain	0	Direct
Heat shock protein 90, HSP90, N-terminal domain	0	Direct
Tetraspanin	0	Direct
AAT-like	0	Direct
6-phosphogluconate dehydrogenase-like, N-terminal domain	0	Direct
L27 domain	0	Direct
DEATH domain, DD	0	Direct
1,3-glucuronyltransferase	0	Direct
p120GAP domain-like	0	Direct
L domain	0	Direct
Class I glutamine amidotransferases (GAT)	0	Direct
Diap1 N-terninal region-like	0	Direct
Regulator of G-protein signaling, RGS	0	Direct
beta-N-acetylhexosaminidase catalytic domain	0	Direct
Alkaline phosphatase	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains	0	Direct
Cell cycle control phosphatase, catalytic domain	0	Direct
EF-hand modules in multidomain proteins	0	Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
DPP6 N-terminal domain-like	0	Direct
Arylsulfatase	0	Direct
PAPS sulfotransferase	0	Direct
Ovomucoid domain III-like	0	Direct
PDEase	0	Direct
NHL repeat	0	Direct
Dimeric isocitrate & isopropylmalate dehydrogenases	0	Direct
Glucose 6-phosphate dehydrogenase-like	0	Direct
SPRY domain	0	Direct
Inositol polyphosphate 5-phosphatase (IPP5)	0	Direct
UBX domain	0	Direct
N-terminal domain of adrenodoxin reductase-like	0	Direct
Cystathionine synthase-like	0	Direct
VPS9 domain	0	Direct
DPP6 catalytic domain-like	0	Direct
Formin homology 2 domain (FH2 domain)	0	Direct
Integrin domains	0	Direct
Band 7/SPFH domain	0	Direct
Aldo-keto reductases (NADP)	0	Direct
B-box zinc-binding domain	0	Direct
acyl-CoA oxidase C-terminal domains	0	Direct
Type II chitinase	0	Direct
Calpain large subunit, catalytic domain (domain II)	0	Direct
acyl-CoA oxidase N-terminal domains	0	Direct
MutT-like	0	Direct
Chitinase insertion domain	0	Direct
Cell cycle transcription factor e2f-dp	0	Direct
FMN-linked oxidoreductases	0	Direct
Formate/glycerate dehydrogenases, substrate-binding domain	0	Direct

Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term

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Supra-domain (including individual superfamily)

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Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
N-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
NAD(P)-linked oxidoreductase	0	Direct
FMN-linked oxidoreductases	0	Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
HD-domain/PDEase-like	0	Direct
Composite domain of metallo-dependent hydrolases	0	Direct
alpha-helical ferredoxin	0	Direct
Seven-hairpin glycosidases	0	Direct
Isocitrate/Isopropylmalate dehydrogenase-like	0	Direct
L27 domain	0	Direct
alpha-catenin/vinculin-like	0	Direct
Formin homology 2 domain (FH2 domain)	0	Direct
Carboxypeptidase regulatory domain-like	0	Direct
Class I glutamine amidotransferase-like	0	Direct
beta-N-acetylhexosaminidase-like domain	0	Direct
GAT-like domain	0	Direct
E2F-DP heterodimerization region	0	Direct
Chitinase insertion domain	0	Direct
FnI-like domain	0	Direct
Phospholipase A2, PLA2	0	Direct
6-phosphogluconate dehydrogenase C-terminal domain-like	0	Direct
Insulin-like	0	Direct
TIMP-like	0	Direct
Regulator of G-protein signaling, RGS	0	Direct
Ribosomal proteins S24e, L23 and L15e	0	Direct
Acyl-CoA dehydrogenase NM domain-like	0	Direct
PapD-like	0	Direct
HSP90 C-terminal domain	0	Direct
DPP6 N-terminal domain-like	0	Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	0	Direct
Nucleotide-binding domain	0	Direct
B-box zinc-binding domain	0	Direct
VPS9 domain	0	Direct
Acyl-CoA dehydrogenase C-terminal domain-like	0	Direct
Integrin alpha N-terminal domain	0	Direct
NHL repeat	0	Direct
Integrin domains	0	Direct

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Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
49313,49313 49313 - Cadherin-like 49313 - Cadherin-like	0	Direct
57196,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases	0	Direct
53901,53901 53901 - Thiolase-like 53901 - Thiolase-like	0	Direct
101288,50156 101288 - L27 domain 50156 - PDZ domain-like	0	Direct
57196,57184 57196 - EGF/Laminin 57184 - Growth factor receptor domain	0	Direct
50615,52540 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase 52540 - P-loop containing nucleoside triphosphate hydrolases	0	Direct
56645,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like	0	Direct
47220,47220 47220 - alpha-catenin/vinculin-like 47220 - alpha-catenin/vinculin-like	0	Direct
55545,51445 55545 - beta-N-acetylhexosaminidase-like domain 51445 - (Trans)glycosidases	0	Direct
55550,56112 55550 - SH2 domain 56112 - Protein kinase-like (PK-like)	0	Direct
46785,144074 46785 - "Winged helix" DNA-binding domain 144074 - E2F-DP heterodimerization region	0	Direct
63877,81321 63877 - Methuselah ectodomain 81321 - Family A G protein-coupled receptor-like	0	Direct
57184,63825 57184 - Growth factor receptor domain 63825 - YWTD domain	0	Direct
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
103473,103473 103473 - MFS general substrate transporter 103473 - MFS general substrate transporter	0	Direct
49899,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin	0	Direct
82171,53474 82171 - DPP6 N-terminal domain-like 53474 - alpha/beta-Hydrolases	0	Direct
51735,48179 51735 - NAD(P)-binding Rossmann-fold domains 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like	0	Direct
51445,54556 51445 - (Trans)glycosidases 54556 - Chitinase insertion domain	0	Direct
81324,81324 81324 - Voltage-gated potassium channels 81324 - Voltage-gated potassium channels	0	Direct
57424,57184 57424 - LDL receptor-like module 57184 - Growth factor receptor domain	0	Direct
48464,89009 48464 - ENTH/VHS domain 89009 - GAT-like domain	0	Direct
47203,47203 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like	0	Direct

(show details)

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
57196,49899,49899 57196 - EGF/Laminin 49899 - Concanavalin A-like lectins/glucanases 49899 - Concanavalin A-like lectins/glucanases	0	Direct
57196,57184,57196 57196 - EGF/Laminin 57184 - Growth factor receptor domain 57196 - EGF/Laminin	0	Direct
57850,57850,57850 57850 - RING/U-box 57850 - RING/U-box 57850 - RING/U-box	0	Direct
49313,49313,49313 49313 - Cadherin-like 49313 - Cadherin-like 49313 - Cadherin-like	0	Direct
101288,50156,50044 101288 - L27 domain 50156 - PDZ domain-like 50044 - SH3-domain	0	Direct
50615,52540,47917 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase	0	Direct
57424,57184,63825 57424 - LDL receptor-like module 57184 - Growth factor receptor domain 63825 - YWTD domain	0	Direct
56645,47203,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like	0	Direct
49899,57196,57196 49899 - Concanavalin A-like lectins/glucanases 57196 - EGF/Laminin 57196 - EGF/Laminin	0	Direct
57424,57424,57184 57424 - LDL receptor-like module 57424 - LDL receptor-like module 57184 - Growth factor receptor domain	0	Direct

Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term

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Fly Phenotype (FP): viable

Superfamily

Family

Supra-domain (including individual superfamily)