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Fly Phenotype (FP): phenotype
(show info)
Phenotype Ontology
Like Gene Ontology (GO), phenotypy ontology classifies and organizes gene-mutant/null phenotypic information from the very general at the top to more specific terms in the directed acyclic graph (DAG) by viewing an individual term as a node and its relations to parental terms (allowing for multiple parents) as directed edges. To navigate this hierarchy, we display all parental phenotypic terms to the current phenotypic term of interest ordered by their shortest distances to the current term. Also, only direct children phenotypic terms of the current phenotypic term are listed. Phenotype ontologies we have incorporated are as follows:
- Disease Ontology (DO) Ontology (DO) DO semantically integrates disease and medical vocabularies through extensive cross mapping of DO terms to MeSH, ICD, NCI thesaurus, SNOMED and OMIM.
- Human Phenotype (HP) Ontology (HP) HP captures phenotypic abnormalities that are described in OMIM, along with the corresponding disease-causing genes. It includes three complementary biological concepts: Mode_of_Inheritance (MI), ONset_and_clinical_course (ON), and Phenotypic_Abnormality (PA).
- Mouse Phenotype (MP) Ontology (MP) MP describes phenotypes of the mouse after a specific gene is genetically disrupted. Using it, Mouse Genome Informatics (MGI) provides high-coverate gene-level phenotypes for the mouse.
- Worm Phenotype (WP) Ontology (WP) WP classifies and organizes phenotype descriptions for C. elegans and other nematodes. Using it, WormBase provides primary resource for phenotype annotations for C. elegans.
- Yeast Phenotype (YP) Ontology (YP) Based on YP which is the major contributor to the Ascomycete phenotype ontology, Saccharomyces Genome Database (SGD) provides single mutant phenotypes for every gene in the yeast genome.
- Fly Phenotype (FP) Ontology (FP) FP refers to FlyBase controlled vocabulary. Specifically, a structured controlled vocabulary is used for the annotation of alleles (for their mutagen etc) in FlyBase.
- Fly Anatomy (FA) Ontology (FA) FA is a structured controlled vocabulary of the anatomy of Drosophila melanogaster, used for the description of phenotypes and where a gene is expressed.
- Zebrafish Anatomy (ZA) Ontology (ZA) ZA displays anatomical terms of the zebrafish using standard anatomical nomenclature, together with affected genes.
- Xenopus Anatomy (XA) Ontology (XA) XA represents the lineage of tissues and the timing of development for frogs (Xenopus laevis and Xenopus tropicalis). It is used to annotate Xenopus gene expression patterns and mutant and morphant phenotypes.
- Arabidopsis Plant Ontology (AP) Ontology (AP) As a major contributor to Plant Ontology which describes plant anatomical and morphological structures (AN) and growth and developmental stages (DE), the Arabidopsis Information Resource (TAIR) provides arabidopsis plant ontology annotations for the model higher plant Arabidopsis thaliana.
- Enzyme Commission (EC) Ontology (EC) Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed.
- DrugBank ATC (DB) Ontology (DB) In the Anatomical Therapeutic Chemical (ATC) classification system, drugs are classified in groups at five different levels according to the organ or system (1st level, anatomical main group) on which they act and their therapeutic (2nd level, therapeutic subgroup), pharmacological (3rd level, pharmacological subgroup) and chemical properties (4th level, chemical subgroup; 5th level, chemical substance). Only drugs in DrugBank are considered.
- UniProtKB KeyWords (KW) Ontology (KW) Keywords in UniProtKB are controlled vocabulary, providing a summary of the entry content and are used to index UniProtKB/Swiss-Prot entries based on 10 categories (the category "Technical term" being excluded here). Each keyword is attributed manually to UniProtKB/Swiss-Prot entries and automatically to UniProtKB/TrEMBL entries (according to specific annotation rules).
- UniProtKB UniPathway (UP) Ontology (UP) UP is a fully manually curated resource for the representation and annotation of metabolic pathways, being used as controlled vocabulary for pathway annotation in UniProtKB.
Structural Domain Phenotype Ontology and its Annotations
Structural Classification of Proteins (SCOP) classifies evolutionary-related domains into Superfamily level and Family level. Using the phenotype ontologies above, we have generated the domain-centric phenotype annotations, and further identified those phenotype terms which are the most informative to annotate SCOP domains. Promisingly, domain-centric phenotypic annotations can serve as an alternative starting point to explore genotype-phenotype relationships. We provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Structural Domain Disease Ontology (DO) Ontology (SDDO) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DO.txt, and the corresponding ontology:SDDO.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Human Phenotype (HP) Ontology (SDHP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2HP.txt, and the corresponding ontology:SDHP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Mouse Phenotype (MP) Ontology (SDMP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2MP.txt, and the corresponding ontology:SDMP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Worm Phenotype (WP) Ontology (SDWP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2WP.txt, and the corresponding ontology:SDWP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Yeast Phenotype (YP) Ontology (SDYP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2YP.txt, and the corresponding ontology:SDYP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Phenotype (FP) Ontology (SDFP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FP.txt, and the corresponding ontology:SDFP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Fly Anatomy (FA) Ontology (SDFA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2FA.txt, and the corresponding ontology:SDFA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Zebrafish Anatomy (ZA) Ontology (SDZA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2ZA.txt, and the corresponding ontology:SDZA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Xenopus Anatomy (XA) Ontology (SDXA) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2XA.txt, and the corresponding ontology:SDXA.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Arabidopsis Plant Ontology (AP) Ontology (SDAP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2AP.txt, and the corresponding ontology:SDAP.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain Enzyme Commission (EC) Ontology (SDEC) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2EC.txt, and the corresponding ontology:SDEC.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain DrugBank ATC (DB) Ontology (SDDB) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2DB.txt, and the corresponding ontology:SDDB.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB KeyWords (KW) Ontology (SDKW) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2KW.txt, and the corresponding ontology:SDKW.txt) and mysql tables (Domain2PO.sql.gz).
- Structural Domain UniProtKB UniPathway (UP) Ontology (SDUP) and its Annotations: For details, please visit Document: PO annotation for SCOP domains, wherein Data Availability contains parsable flat files (the annotation:Domain2UP.txt, and the corresponding ontology:SDUP.txt) and mysql tables (Domain2PO.sql.gz).
Supra-domain Phenotype Ontology and its Annotations
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are interested in domain combinations. Also, we provide several relevant files for the download, including the annotation and the corresponding ontology for each phenotype ontology.
- Supra-domain Domain Disease Ontology (DO) Ontology (SPDO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DO.txt, and the corresponding ontology:SPDO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Human Phenotype (HP) Ontology (SPHO) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2HP.txt, and the corresponding ontology:SPHO.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Mouse Phenotype (MP) Ontology (SPMP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2MP.txt, and the corresponding ontology:SPMP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Worm Phenotype (WP) Ontology (SPWP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2WP.txt, and the corresponding ontology:SPWP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Yeast Phenotype (YP) Ontology (SPYP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2YP.txt, and the corresponding ontology:SPYP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Phenotype (FP) Ontology (SPFP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FP.txt, and the corresponding ontology:SPFP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Fly Anatomy (FA) Ontology (SPFA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2FA.txt, and the corresponding ontology:SPFA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Zebrafish Anatomy (ZA) Ontology (SPZA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2ZA.txt, and the corresponding ontology:SPZA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Xenopus Anatomy (XA) Ontology (SPXA) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2XA.txt, and the corresponding ontology:SPXA.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Arabidopsis Plant Ontology (AP) Ontology (SPAP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2AP.txt, and the corresponding ontology:SPAP.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain Enzyme Commission (EC) Ontology (SPEC) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2EC.txt, and the corresponding ontology:SPEC.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain DrugBank ATC (DB) Ontology (SPDB) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2DB.txt, and the corresponding ontology:SPDB.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB KeyWords (KW) Ontology (SPKW) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2KW.txt, and the corresponding ontology:SPKW.txt) and mysql tables (SP2PO.sql.gz).
- Supra-domain Domain UniProtKB UniPathway (UP) Ontology (SPUP) and its Annotations: For details, please visit Document: PO annotation for Supra-domains, wherein Data Availability contains parsable flat files (the annotation:SP2UP.txt, and the corresponding ontology:SPUP.txt) and mysql tables (SP2PO.sql.gz).
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Root: FP Hierarchy (fly phenotype from FlyBase controlled vocabulary with sub-ontology "phenotypic class")
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this FP term (Not in SDFP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| FtsH protease domain-like | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Cytokine | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Bet v1-like | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Orange domain-like | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| Toll/Interleukin receptor TIR domain | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Periplasmic binding protein-like I | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| Lipocalins | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Nucleoporin domain | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| Taf5 N-terminal domain-like | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Translation proteins SH3-like domain | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Homeodomain-like | 0.0000049 | DIRECT |
| ARM repeat | 0.00004337 | DIRECT |
| SH3-domain | 0.0001039 | DIRECT |
| Protein kinase-like (PK-like) | 0.000374 | DIRECT |
| EGF/Laminin | 0.01653 | INHERITED FROM: immune response defective || lethal - all die before end of P-stage || lethal - all die before end of pupal stage || lethal - all die before end of first instar larval stage || lethal - all die before end of prepupal stage || planar polarity defective || lethal - all die before end of larval stage || lethal - all die before end of embryonic stage || some die during embryonic stage || cell polarity defective |
| p53-like transcription factors | 0.0731 | INHERITED FROM: size defective |
| Cysteine-rich domain | 0.0731 | INHERITED FROM: wound healing defective |
| Nucleotidylyl transferase | 0.0731 | INHERITED FROM: decreased cell size |
| beta-sandwich domain of Sec23/24 | 0.08651 | INHERITED FROM: some die during larval stage || lethal - all die before end of pupal stage || cell shape defective || lethal - all die before end of larval stage || lethal - all die before end of embryonic stage |
| PDZ domain-like | 0.09537 | INHERITED FROM: cell polarity defective |
| Leucine zipper domain | 0.0987 | INHERITED FROM: developmental rate defective || increased mortality || lethal - all die before end of pupal stage || lethal - all die before end of first instar larval stage || lethal - all die before end of larval stage |
| Cyclin-like | 0.115 | INHERITED FROM: mitotic cell cycle defective || cell cycle defective |
| Periplasmic binding protein-like II | 0.1248 | INHERITED FROM: feeding behavior defective || sensory perception defective || neurophysiology defective |
| FYVE/PHD zinc finger | 0.129 | INHERITED FROM: modifier of variegation |
| BRCT domain | 0.1337 | INHERITED FROM: radiation sensitive |
| EF-hand | 0.1349 | INHERITED FROM: flightless |
| SNARE fusion complex | 0.1555 | INHERITED FROM: increased mortality during development || neurophysiology defective || uncoordinated |
| Fibronectin type III | 0.1658 | INHERITED FROM: cell adhesion defective |
| beta-beta-alpha zinc fingers | 0.1953 | INHERITED FROM: visible |
| Concanavalin A-like lectins/glucanases | 0.2241 | INHERITED FROM: cell polarity defective |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.2332 | INHERITED FROM: neurophysiology defective |
| N-acetylmuramoyl-L-alanine amidase-like | 0.2449 | INHERITED FROM: immune response defective |
| Tudor/PWWP/MBT | 0.2667 | INHERITED FROM: sterile || neoplasia |
| Cysteine proteinases | 0.2737 | INHERITED FROM: behavior defective |
| Chromo domain-like | 0.295 | INHERITED FROM: modifier of variegation || non-suppressor of variegation || suppressor of variegation |
| Ankyrin repeat | 0.3104 | INHERITED FROM: temperature response defective || thermotaxis behavior defective || behavior defective || courtship behavior defective || sensory perception defective || neurophysiology defective |
| HMG-box | 0.3172 | INHERITED FROM: visible |
| P-loop containing nucleoside triphosphate hydrolases | 0.3696 | INHERITED FROM: cell cycle defective |
| Macro domain-like | 0.3766 | INHERITED FROM: male sterile || sterile |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4092 | INHERITED FROM: chemical resistant || phototaxis defective |
| Nicotinic receptor ligand binding domain-like | 0.4092 | INHERITED FROM: chemical resistant || phototaxis defective |
| SH2 domain | 0.4162 | INHERITED FROM: planar polarity defective |
| Voltage-gated potassium channels | 0.4484 | INHERITED FROM: chemical resistant || chemical sensitive || behavior defective || chemosensitive behavior defective || neurophysiology defective || circadian rhythm defective |
| Growth factor receptor domain | 0.4484 | INHERITED FROM: planar polarity defective || cell polarity defective |
| SCOP hierarchy in SUPERFAMILY | 0.4514 | INHERITED FROM: Minute |
| Cystine-knot cytokines | 0.4929 | INHERITED FROM: circadian rhythm defective |
| POZ domain | 0.493 | INHERITED FROM: body color defective || sleep defective |
| PAZ domain | 0.5003 | INHERITED FROM: modifier of variegation || mitotic cell cycle defective || cell cycle defective || suppressor of variegation |
| Tubulin nucleotide-binding domain-like | 0.5552 | INHERITED FROM: cell cycle defective |
| Family A G protein-coupled receptor-like | 0.5623 | INHERITED FROM: hypoactive || behavior defective || mating defective |
| RNA-binding domain, RBD | 0.5757 | INHERITED FROM: lethal |
| Ribonuclease H-like | 0.5939 | INHERITED FROM: melanotic mass phenotype |
| Cadherin-like | 0.6221 | INHERITED FROM: cell polarity defective |
| cAMP-binding domain-like | 0.6221 | INHERITED FROM: hyperactive || sensory perception defective |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.6425 | INHERITED FROM: visible |
| Immunoglobulin | 0.7429 | INHERITED FROM: cell migration defective |
| SET domain | 0.7471 | INHERITED FROM: modifier of variegation || non-suppressor of variegation || suppressor of variegation || homeotic |
| Nucleotide cyclase | 0.8548 | INHERITED FROM: taste perception defective |
| NAD(P)-binding Rossmann-fold domains | 0.9418 | INHERITED FROM: electrophoretic variant |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: electrophoretic variant |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| FtsH protease domain-like | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| Integrin domains | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| ACT-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Ferritin-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Cytokine | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| Sema domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Prefoldin | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Bromodomain | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| L30e-like | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Bet v1-like | 0 | Direct |
| Sec7 domain | 0 | Direct |
| ARID-like | 0 | Direct |
| Orange domain-like | 0 | Direct |
| DEATH domain | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| vWA-like | 0 | Direct |
| TIMP-like | 0 | Direct |
| Toll/Interleukin receptor TIR domain | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Periplasmic binding protein-like I | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| Caspase-like | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| SAND domain-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| Insulin-like | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| L27 domain | 0 | Direct |
| PX domain | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| PIN domain-like | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| Lipocalins | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Nucleoporin domain | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| Nop domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| Taf5 N-terminal domain-like | 0 | Direct |
| SAP domain | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Tropomyosin | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| KA1-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| ACP-like | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Aldolase | 0 | Direct |
| PapD-like | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| HRDC-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| SNARE-like | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Translation proteins SH3-like domain | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Homeodomain-like | 0.0000049 | Direct |
| ARM repeat | 0.00004337 | Direct |
| SH3-domain | 0.0001039 | Direct |
| Protein kinase-like (PK-like) | 0.000374 | Direct |
| EGF/Laminin | 0.01653 | Inherited |
| p53-like transcription factors | 0.0731 | Inherited |
| Cysteine-rich domain | 0.0731 | Inherited |
| Nucleotidylyl transferase | 0.0731 | Inherited |
| beta-sandwich domain of Sec23/24 | 0.08651 | Inherited |
| PDZ domain-like | 0.09537 | Inherited |
| Leucine zipper domain | 0.0987 | Inherited |
| Cyclin-like | 0.115 | Inherited |
| Periplasmic binding protein-like II | 0.1248 | Inherited |
| FYVE/PHD zinc finger | 0.129 | Inherited |
| BRCT domain | 0.1337 | Inherited |
| EF-hand | 0.1349 | Inherited |
| SNARE fusion complex | 0.1555 | Inherited |
| Fibronectin type III | 0.1658 | Inherited |
| beta-beta-alpha zinc fingers | 0.1953 | Inherited |
| Concanavalin A-like lectins/glucanases | 0.2241 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.2332 | Inherited |
| N-acetylmuramoyl-L-alanine amidase-like | 0.2449 | Inherited |
| Tudor/PWWP/MBT | 0.2667 | Inherited |
| Cysteine proteinases | 0.2737 | Inherited |
| Chromo domain-like | 0.295 | Inherited |
| Ankyrin repeat | 0.3104 | Inherited |
| HMG-box | 0.3172 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.3696 | Inherited |
| Macro domain-like | 0.3766 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4092 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.4092 | Inherited |
| SH2 domain | 0.4162 | Inherited |
| Voltage-gated potassium channels | 0.4484 | Inherited |
| Growth factor receptor domain | 0.4484 | Inherited |
| SCOP hierarchy in SUPERFAMILY | 0.4514 | Inherited |
| Cystine-knot cytokines | 0.4929 | Inherited |
| POZ domain | 0.493 | Inherited |
| PAZ domain | 0.5003 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.5552 | Inherited |
| Family A G protein-coupled receptor-like | 0.5623 | Inherited |
| RNA-binding domain, RBD | 0.5757 | Inherited |
| Ribonuclease H-like | 0.5939 | Inherited |
| Cadherin-like | 0.6221 | Inherited |
| cAMP-binding domain-like | 0.6221 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.6425 | Inherited |
| Immunoglobulin | 0.7429 | Inherited |
| SET domain | 0.7471 | Inherited |
| Nucleotide cyclase | 0.8548 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.9418 | Inherited |
| alpha/beta-Hydrolases | 1 | Inherited |
Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this FP term (Not in SDFP)
Highlighted in gray are those with FDR_all>0.001
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| MSP-like | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Single strand DNA-binding domain, SSB | 0 | DIRECT |
| Hsp90 middle domain | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| beta-CASP RNA-metabolising hydrolases | 0 | DIRECT |
| Fibroblast growth factors (FGF) | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | DIRECT |
| S-adenosylhomocystein hydrolase | 0 | DIRECT |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | DIRECT |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| a tRNA synthase domain | 0 | DIRECT |
| Anticodon-binding domain of Class II aaRS | 0 | DIRECT |
| GroEL-like chaperone, intermediate domain | 0 | DIRECT |
| Extracellular domain of cell surface receptors | 0 | DIRECT |
| Hairy Orange domain | 0 | DIRECT |
| Ngr ectodomain-like | 0 | DIRECT |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| Nuclear receptor | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | DIRECT |
| TBP-associated factors, TAFs | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| PLC-like (P variant) | 0 | DIRECT |
| TATA-box binding protein (TBP), C-terminal domain | 0 | DIRECT |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| DEATH domain, DD | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| IF2B-like | 0 | DIRECT |
| Clathrin adaptor core protein | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Laminin-type module | 0 | DIRECT |
| Class I glutamine amidotransferases (GAT) | 0 | DIRECT |
| Meta-cation ATPase, catalytic domain P | 0 | DIRECT |
| Diap1 N-terninal region-like | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| POU-specific domain | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| MBT repeat | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Dachshund-homology domain | 0 | DIRECT |
| Caspase catalytic domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| Zf-UBP | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| L30e/L7ae ribosomal proteins | 0 | DIRECT |
| Pointed domain | 0 | DIRECT |
| Transcriptional factor domain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| BC C-terminal domain-like | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Reprolysin-like | 0 | DIRECT |
| BAR domain | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| Cell cycle control phosphatase, catalytic domain | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| FHA domain | 0 | DIRECT |
| Astacin | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| NLI interacting factor-like phosphatase | 0 | DIRECT |
| Chromo barrel domain | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| Acyl-carrier protein (ACP) | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| PAPS sulfotransferase | 0 | DIRECT |
| Neurolysin-like | 0 | DIRECT |
| Sedlin (SEDL) | 0 | DIRECT |
| Ubiquitin activating enzymes (UBA) | 0 | DIRECT |
| BC N-terminal domain-like | 0 | DIRECT |
| Nitrogenase iron protein-like | 0 | DIRECT |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | DIRECT |
| First domain of FERM | 0 | DIRECT |
| CAD domain | 0 | DIRECT |
| NHL repeat | 0 | DIRECT |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | DIRECT |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Leucine aminopeptidase (Aminopeptidase A), N-terminal domain | 0 | DIRECT |
| Isoprenyl diphosphate synthases | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | DIRECT |
| XPF/Rad1/Mus81 nuclease | 0 | DIRECT |
| MIF4G domain-like | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| Transforming growth factor (TGF)-beta | 0 | DIRECT |
| RUNT domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | DIRECT |
| Ribonuclease PH domain 1-like | 0 | DIRECT |
| Histidine acid phosphatase | 0 | DIRECT |
| Ferredoxin domains from multidomain proteins | 0 | DIRECT |
| Toll/Interleukin receptor TIR domain | 0 | DIRECT |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| La domain | 0 | DIRECT |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | DIRECT |
| Protein serine/threonine phosphatase | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| ZZ domain | 0 | DIRECT |
| Leucine aminopeptidase, C-terminal domain | 0 | DIRECT |
| Eps15 homology domain (EH domain) | 0 | DIRECT |
| Taf5 N-terminal domain-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Double-stranded RNA-binding domain (dsRBD) | 0 | DIRECT |
| ets domain | 0 | DIRECT |
| Subtilases | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| Calmodulin-like | 0 | DIRECT |
| Arrestin/Vps26-like | 0 | DIRECT |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | DIRECT |
| Cyclin | 0 | DIRECT |
| Inositol polyphosphate kinase (IPK) | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| Calpain large subunit, catalytic domain (domain II) | 0 | DIRECT |
| Clathrin coat assembly domain | 0 | DIRECT |
| Erythroid transcription factor GATA-1 | 0 | DIRECT |
| ARID domain | 0 | DIRECT |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | DIRECT |
| BC ATP-binding domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase, beta-chain, N-terminal domain | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| L-arabinose binding protein-like | 0 | DIRECT |
| Rhomboid-like | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| Cell cycle transcription factor e2f-dp | 0 | DIRECT |
| SMAD domain | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | DIRECT |
| Paired domain | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Myb/SANT domain | 0 | DIRECT |
| GroEL chaperone, ATPase domain | 0 | DIRECT |
| RecA protein-like (ATPase-domain) | 0 | DIRECT |
| Penta-EF-hand proteins | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| T-box | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| Gelsolin-like | 0 | DIRECT |
| RNase III catalytic domain-like | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Laminin G-like module | 0 | DIRECT |
| Forkhead DNA-binding domain | 0 | DIRECT |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| Armadillo repeat | 0 | DIRECT |
| GroEL-like chaperone, apical domain | 0 | DIRECT |
| MAM domain | 0 | DIRECT |
| H-NOX domain | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| Histone lysine methyltransferases | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| GMC oxidoreductases | 0 | DIRECT |
| Protein kinases, catalytic subunit | 0.00001477 | DIRECT |
| Homeodomain | 0.00003692 | DIRECT |
| SH3-domain | 0.0002296 | DIRECT |
| PDZ domain | 0.01872 | INHERITED FROM: cell polarity defective |
| Motor proteins | 0.03489 | INHERITED FROM: lethal - all die before end of first instar larval stage || lethal - all die before end of larval stage || cell cycle defective || lethal - all die before end of embryonic stage || auditory perception defective |
| I set domains | 0.06292 | INHERITED FROM: cell migration defective |
| EGF-type module | 0.08341 | INHERITED FROM: tumorigenic || decreased occurrence of cell division || hyperplasia || lethal - all die before end of prepupal stage || planar polarity defective || lethal - all die before end of larval stage || some die during pupal stage || cell polarity defective || increased cell number || increased occurrence of cell division |
| Tandem AAA-ATPase domain | 0.1074 | INHERITED FROM: increased mortality || DNA repair defective || radiation sensitive |
| Phosphate binding protein-like | 0.1111 | INHERITED FROM: neurophysiology defective |
| Leucine zipper domain | 0.1111 | INHERITED FROM: developmental rate defective || lethal - all die before end of pupal stage || lethal - all die before end of first instar larval stage || lethal - all die before end of larval stage |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.1703 | INHERITED FROM: cell size defective || decreased cell size |
| SAM (sterile alpha motif) domain | 0.1947 | INHERITED FROM: homeotic || neoplasia |
| Fibronectin type III | 0.2245 | INHERITED FROM: cell adhesion defective |
| PHD domain | 0.2516 | INHERITED FROM: modifier of variegation || homeotic |
| Dual specificity phosphatase-like | 0.2538 | INHERITED FROM: chemical resistant |
| N-acetylmuramoyl-L-alanine amidase-like | 0.2538 | INHERITED FROM: immune response defective |
| Rhodopsin-like | 0.3562 | INHERITED FROM: hypoactive || behavior defective || courtship behavior defective || mating defective |
| Classic zinc finger, C2H2 | 0.3585 | INHERITED FROM: visible |
| Extended AAA-ATPase domain | 0.3775 | INHERITED FROM: bang sensitive |
| Pancreatic lipase, N-terminal domain | 0.3798 | INHERITED FROM: electrophoretic variant |
| Tetramerization domain of potassium channels | 0.3798 | INHERITED FROM: courtship behavior defective || sleep defective || mating defective || neurophysiology defective || circadian rhythm defective |
| Ankyrin repeat | 0.4025 | INHERITED FROM: temperature response defective || thermotaxis behavior defective || behavior defective || chemosensitive behavior defective || sensory perception defective || neurophysiology defective |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4318 | INHERITED FROM: chemical resistant || phototaxis defective |
| Glutathione peroxidase-like | 0.4364 | INHERITED FROM: stress response defective |
| SH2 domain | 0.4644 | INHERITED FROM: planar polarity defective |
| Growth factor receptor domain | 0.4746 | INHERITED FROM: immune response defective || planar polarity defective || cell polarity defective |
| UBA domain | 0.5027 | INHERITED FROM: increased cell death |
| Nicotinic receptor ligand binding domain-like | 0.5239 | INHERITED FROM: chemical resistant || phototaxis defective |
| Canonical RBD | 0.5286 | INHERITED FROM: lethal |
| G proteins | 0.564 | INHERITED FROM: immune response defective || body size defective |
| Tubulin, GTPase domain | 0.5795 | INHERITED FROM: cell cycle defective |
| PAZ domain | 0.5797 | INHERITED FROM: modifier of variegation || mitotic cell cycle defective || cell cycle defective || suppressor of variegation |
| Voltage-gated potassium channels | 0.6806 | INHERITED FROM: chemosensitive behavior defective || neurophysiology defective || circadian rhythm defective |
| cAMP-binding domain | 0.6999 | INHERITED FROM: chemical resistant || hyperactive || sensory perception defective |
| Cadherin | 0.6999 | INHERITED FROM: cell polarity defective |
| Acetylcholinesterase-like | 0.7832 | INHERITED FROM: electrophoretic variant |
| Adenylyl and guanylyl cyclase catalytic domain | 0.8784 | INHERITED FROM: taste perception defective |
| Neutral endopeptidase (neprilysin) | 0.9702 | INHERITED FROM: female semi-sterile || semi-sterile |
| SCOP term | FDR (all) | Annotation (direct or inherited) |
| MSP-like | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Single strand DNA-binding domain, SSB | 0 | Direct |
| Hsp90 middle domain | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Insulin-like | 0 | Direct |
| beta-CASP RNA-metabolising hydrolases | 0 | Direct |
| Fibroblast growth factors (FGF) | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| Class I alpha-1;2-mannosidase, catalytic domain | 0 | Direct |
| S-adenosylhomocystein hydrolase | 0 | Direct |
| Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain) | 0 | Direct |
| Sm motif of small nuclear ribonucleoproteins, SNRNP | 0 | Direct |
| PX domain | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| a tRNA synthase domain | 0 | Direct |
| Anticodon-binding domain of Class II aaRS | 0 | Direct |
| GroEL-like chaperone, intermediate domain | 0 | Direct |
| Extracellular domain of cell surface receptors | 0 | Direct |
| Hairy Orange domain | 0 | Direct |
| Ngr ectodomain-like | 0 | Direct |
| Heat shock protein 90, HSP90, N-terminal domain | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| Nuclear receptor | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K), catalytic domain | 0 | Direct |
| TBP-associated factors, TAFs | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| PLC-like (P variant) | 0 | Direct |
| TATA-box binding protein (TBP), C-terminal domain | 0 | Direct |
| NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain | 0 | Direct |
| L27 domain | 0 | Direct |
| DEATH domain, DD | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| IF2B-like | 0 | Direct |
| Clathrin adaptor core protein | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Laminin-type module | 0 | Direct |
| Class I glutamine amidotransferases (GAT) | 0 | Direct |
| Meta-cation ATPase, catalytic domain P | 0 | Direct |
| Diap1 N-terninal region-like | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| POU-specific domain | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| MBT repeat | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase UCH-L | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Dachshund-homology domain | 0 | Direct |
| Caspase catalytic domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| Zf-UBP | 0 | Direct |
| Nop domain | 0 | Direct |
| Bromodomain | 0 | Direct |
| L30e/L7ae ribosomal proteins | 0 | Direct |
| Pointed domain | 0 | Direct |
| Transcriptional factor domain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), ATPase domain | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| BC C-terminal domain-like | 0 | Direct |
| Prefoldin | 0 | Direct |
| Reprolysin-like | 0 | Direct |
| BAR domain | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| Cell cycle control phosphatase, catalytic domain | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| FHA domain | 0 | Direct |
| Astacin | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| 2Fe-2S ferredoxin domains from multidomain proteins | 0 | Direct |
| Rel/Dorsal transcription factors, DNA-binding domain | 0 | Direct |
| Sec7 domain | 0 | Direct |
| NLI interacting factor-like phosphatase | 0 | Direct |
| Chromo barrel domain | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| Acyl-carrier protein (ACP) | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| PAPS sulfotransferase | 0 | Direct |
| Neurolysin-like | 0 | Direct |
| Sedlin (SEDL) | 0 | Direct |
| Ubiquitin activating enzymes (UBA) | 0 | Direct |
| BC N-terminal domain-like | 0 | Direct |
| Nitrogenase iron protein-like | 0 | Direct |
| Hypoxia-inducible factor Hif2a, C-terminal domain | 0 | Direct |
| First domain of FERM | 0 | Direct |
| CAD domain | 0 | Direct |
| NHL repeat | 0 | Direct |
| Dimeric isocitrate & isopropylmalate dehydrogenases | 0 | Direct |
| Alcohol dehydrogenase-like, C-terminal domain | 0 | Direct |
| Leucine aminopeptidase (Aminopeptidase A), N-terminal domain | 0 | Direct |
| Isoprenyl diphosphate synthases | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| Group II chaperonin (CCT, TRIC), apical domain | 0 | Direct |
| XPF/Rad1/Mus81 nuclease | 0 | Direct |
| MIF4G domain-like | 0 | Direct |
| Tropomyosin | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| Transforming growth factor (TGF)-beta | 0 | Direct |
| RUNT domain | 0 | Direct |
| Aminoacid dehydrogenase-like, C-terminal domain | 0 | Direct |
| Ribonuclease PH domain 1-like | 0 | Direct |
| Histidine acid phosphatase | 0 | Direct |
| Ferredoxin domains from multidomain proteins | 0 | Direct |
| Toll/Interleukin receptor TIR domain | 0 | Direct |
| Phoshoinositide 3-kinase (PI3K) helical domain | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| La domain | 0 | Direct |
| Enabled/VASP homology 1 domain (EVH1 domain) | 0 | Direct |
| Protein serine/threonine phosphatase | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| Integrin domains | 0 | Direct |
| ZZ domain | 0 | Direct |
| Leucine aminopeptidase, C-terminal domain | 0 | Direct |
| Eps15 homology domain (EH domain) | 0 | Direct |
| Taf5 N-terminal domain-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Double-stranded RNA-binding domain (dsRBD) | 0 | Direct |
| ets domain | 0 | Direct |
| Subtilases | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| Calmodulin-like | 0 | Direct |
| Arrestin/Vps26-like | 0 | Direct |
| Group II chaperonin (CCT, TRIC), intermediate domain | 0 | Direct |
| Cyclin | 0 | Direct |
| Inositol polyphosphate kinase (IPK) | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| Calpain large subunit, catalytic domain (domain II) | 0 | Direct |
| Clathrin coat assembly domain | 0 | Direct |
| Erythroid transcription factor GATA-1 | 0 | Direct |
| ARID domain | 0 | Direct |
| Ubiquitin carboxyl-terminal hydrolase, UCH | 0 | Direct |
| BC ATP-binding domain-like | 0 | Direct |
| Succinyl-CoA synthetase, beta-chain, N-terminal domain | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| L-arabinose binding protein-like | 0 | Direct |
| Rhomboid-like | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| Cell cycle transcription factor e2f-dp | 0 | Direct |
| SMAD domain | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta | 0 | Direct |
| Paired domain | 0 | Direct |
| SAP domain | 0 | Direct |
| Myb/SANT domain | 0 | Direct |
| GroEL chaperone, ATPase domain | 0 | Direct |
| RecA protein-like (ATPase-domain) | 0 | Direct |
| Penta-EF-hand proteins | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| T-box | 0 | Direct |
| Sema domain | 0 | Direct |
| Gelsolin-like | 0 | Direct |
| RNase III catalytic domain-like | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Laminin G-like module | 0 | Direct |
| Forkhead DNA-binding domain | 0 | Direct |
| Alcohol dehydrogenase-like, N-terminal domain | 0 | Direct |
| Armadillo repeat | 0 | Direct |
| GroEL-like chaperone, apical domain | 0 | Direct |
| MAM domain | 0 | Direct |
| H-NOX domain | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| Histone lysine methyltransferases | 0 | Direct |
| HR1 repeat | 0 | Direct |
| GMC oxidoreductases | 0 | Direct |
| Protein kinases, catalytic subunit | 0.00001477 | Direct |
| Homeodomain | 0.00003692 | Direct |
| SH3-domain | 0.0002296 | Direct |
| PDZ domain | 0.01872 | Inherited |
| Motor proteins | 0.03489 | Inherited |
| I set domains | 0.06292 | Inherited |
| EGF-type module | 0.08341 | Inherited |
| Tandem AAA-ATPase domain | 0.1074 | Inherited |
| Phosphate binding protein-like | 0.1111 | Inherited |
| Leucine zipper domain | 0.1111 | Inherited |
| Class I aminoacyl-tRNA synthetases (RS), catalytic domain | 0.1703 | Inherited |
| SAM (sterile alpha motif) domain | 0.1947 | Inherited |
| Fibronectin type III | 0.2245 | Inherited |
| PHD domain | 0.2516 | Inherited |
| Dual specificity phosphatase-like | 0.2538 | Inherited |
| N-acetylmuramoyl-L-alanine amidase-like | 0.2538 | Inherited |
| Rhodopsin-like | 0.3562 | Inherited |
| Classic zinc finger, C2H2 | 0.3585 | Inherited |
| Extended AAA-ATPase domain | 0.3775 | Inherited |
| Pancreatic lipase, N-terminal domain | 0.3798 | Inherited |
| Tetramerization domain of potassium channels | 0.3798 | Inherited |
| Ankyrin repeat | 0.4025 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.4318 | Inherited |
| Glutathione peroxidase-like | 0.4364 | Inherited |
| SH2 domain | 0.4644 | Inherited |
| Growth factor receptor domain | 0.4746 | Inherited |
| UBA domain | 0.5027 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.5239 | Inherited |
| Canonical RBD | 0.5286 | Inherited |
| G proteins | 0.564 | Inherited |
| Tubulin, GTPase domain | 0.5795 | Inherited |
| PAZ domain | 0.5797 | Inherited |
| Voltage-gated potassium channels | 0.6806 | Inherited |
| cAMP-binding domain | 0.6999 | Inherited |
| Cadherin | 0.6999 | Inherited |
| Acetylcholinesterase-like | 0.7832 | Inherited |
| Adenylyl and guanylyl cyclase catalytic domain | 0.8784 | Inherited |
| Neutral endopeptidase (neprilysin) | 0.9702 | Inherited |
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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A presence/absence matrix is generated using protein domain
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heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this FP term (Not in SPFP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Nucleoporin domain | 0 | DIRECT |
| 2Fe-2S ferredoxin-like | 0 | DIRECT |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | DIRECT |
| SAND domain-like | 0 | DIRECT |
| GroEL-intermediate domain like | 0 | DIRECT |
| DNA/RNA polymerases | 0 | DIRECT |
| GroEL apical domain-like | 0 | DIRECT |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | DIRECT |
| Cu,Zn superoxide dismutase-like | 0 | DIRECT |
| Snake toxin-like | 0 | DIRECT |
| Activating enzymes of the ubiquitin-like proteins | 0 | DIRECT |
| PriA/YqbF domain | 0 | DIRECT |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | DIRECT |
| dsRNA-binding domain-like | 0 | DIRECT |
| DEK C-terminal domain | 0 | DIRECT |
| Clathrin adaptor appendage domain | 0 | DIRECT |
| Orange domain-like | 0 | DIRECT |
| ACP-like | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | DIRECT |
| S15/NS1 RNA-binding domain | 0 | DIRECT |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | DIRECT |
| RBP11-like subunits of RNA polymerase | 0 | DIRECT |
| Smc hinge domain | 0 | DIRECT |
| Spectrin repeat | 0 | DIRECT |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
| 4Fe-4S ferredoxins | 0 | DIRECT |
| GINS helical bundle-like | 0 | DIRECT |
| ValRS/IleRS/LeuRS editing domain | 0 | DIRECT |
| Seven-hairpin glycosidases | 0 | DIRECT |
| Sm-like ribonucleoproteins | 0 | DIRECT |
| Ribosomal L27 protein-like | 0 | DIRECT |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | DIRECT |
| L27 domain | 0 | DIRECT |
| Plexin repeat | 0 | DIRECT |
| Cytokine | 0 | DIRECT |
| L30e-like | 0 | DIRECT |
| Bet v1-like | 0 | DIRECT |
| Roadblock/LC7 domain | 0 | DIRECT |
| Prefoldin | 0 | DIRECT |
| Tropomyosin | 0 | DIRECT |
| Skp1 dimerisation domain-like | 0 | DIRECT |
| PX domain | 0 | DIRECT |
| Taf5 N-terminal domain-like | 0 | DIRECT |
| Succinyl-CoA synthetase domains | 0 | DIRECT |
| CBS-domain pair | 0 | DIRECT |
| Formin homology 2 domain (FH2 domain) | 0 | DIRECT |
| Riboflavin synthase domain-like | 0 | DIRECT |
| DEATH domain | 0 | DIRECT |
| RNase III domain-like | 0 | DIRECT |
| Class I glutamine amidotransferase-like | 0 | DIRECT |
| DNA-binding domain | 0 | DIRECT |
| Hormone receptor domain | 0 | DIRECT |
| CAD & PB1 domains | 0 | DIRECT |
| PreATP-grasp domain | 0 | DIRECT |
| GroEL equatorial domain-like | 0 | DIRECT |
| PIN domain-like | 0 | DIRECT |
| Class II aaRS ABD-related | 0 | DIRECT |
| vWA-like | 0 | DIRECT |
| Glutamine synthetase/guanido kinase | 0 | DIRECT |
| A DNA-binding domain in eukaryotic transcription factors | 0 | DIRECT |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
| E2F-DP heterodimerization region | 0 | DIRECT |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | DIRECT |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | DIRECT |
| Zn-binding ribosomal proteins | 0 | DIRECT |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | DIRECT |
| SMAD MH1 domain | 0 | DIRECT |
| HR1 repeat | 0 | DIRECT |
| Ribosomal protein S5 domain 2-like | 0 | DIRECT |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | DIRECT |
| Sec1/munc18-like (SM) proteins | 0 | DIRECT |
| KA1-like | 0 | DIRECT |
| Mob1/phocein | 0 | DIRECT |
| Insulin-like | 0 | DIRECT |
| TIMP-like | 0 | DIRECT |
| Regulator of G-protein signaling, RGS | 0 | DIRECT |
| Putative DNA-binding domain | 0 | DIRECT |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | DIRECT |
| FtsH protease domain-like | 0 | DIRECT |
| lambda repressor-like DNA-binding domains | 0 | DIRECT |
| Ferritin-like | 0 | DIRECT |
| HRDC-like | 0 | DIRECT |
| SAICAR synthase-like | 0 | DIRECT |
| Rudiment single hybrid motif | 0 | DIRECT |
| HLH, helix-loop-helix DNA-binding domain | 0 | DIRECT |
| Restriction endonuclease-like | 0 | DIRECT |
| JAB1/MPN domain | 0 | DIRECT |
| Aldolase | 0 | DIRECT |
| Aquaporin-like | 0 | DIRECT |
| ARID-like | 0 | DIRECT |
| Sema domain | 0 | DIRECT |
| SPOC domain-like | 0 | DIRECT |
| Zinc beta-ribbon | 0 | DIRECT |
| Retrovirus zinc finger-like domains | 0 | DIRECT |
| PapD-like | 0 | DIRECT |
| Translation proteins SH3-like domain | 0 | DIRECT |
| HSP90 C-terminal domain | 0 | DIRECT |
| Ribosomal protein L1 | 0 | DIRECT |
| TATA-box binding protein-like | 0 | DIRECT |
| Transducin (alpha subunit), insertion domain | 0 | DIRECT |
| SMAD/FHA domain | 0 | DIRECT |
| Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
| Ribonuclease PH domain 2-like | 0 | DIRECT |
| B-box zinc-binding domain | 0 | DIRECT |
| Caspase-like | 0 | DIRECT |
| PYP-like sensor domain (PAS domain) | 0 | DIRECT |
| Pectin lyase-like | 0 | DIRECT |
| Toll/Interleukin receptor TIR domain | 0 | DIRECT |
| Bromodomain | 0 | DIRECT |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | DIRECT |
| ACT-like | 0 | DIRECT |
| Integrin domains | 0 | DIRECT |
| Sec7 domain | 0 | DIRECT |
| Periplasmic binding protein-like I | 0 | DIRECT |
| Terpenoid synthases | 0 | DIRECT |
| SNARE-like | 0 | DIRECT |
| SAP domain | 0 | DIRECT |
| Lipocalins | 0 | DIRECT |
| Nop domain | 0 | DIRECT |
| Nuclear receptor ligand-binding domain | 0 | DIRECT |
| Subtilisin-like | 0 | DIRECT |
| ThrRS/AlaRS common domain | 0 | DIRECT |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | DIRECT |
| Translational machinery components | 0 | DIRECT |
| Homeodomain-like | 0.000003536 | DIRECT |
| ARM repeat | 0.00003195 | DIRECT |
| SH3-domain | 0.00007731 | DIRECT |
| Protein kinase-like (PK-like) | 0.0002821 | DIRECT |
| EGF/Laminin | 0.01358 | INHERITED FROM: lethal - all die before end of P-stage || some die during embryonic stage || lethal - all die before end of pupal stage || lethal - all die before end of prepupal stage || planar polarity defective || cell polarity defective || lethal - all die before end of first instar larval stage || lethal - all die before end of embryonic stage || immune response defective || lethal - all die before end of larval stage |
| Cysteine-rich domain | 0.06332 | INHERITED FROM: wound healing defective |
| Nucleotidylyl transferase | 0.06332 | INHERITED FROM: decreased cell size |
| p53-like transcription factors | 0.06332 | INHERITED FROM: size defective |
| beta-sandwich domain of Sec23/24 | 0.07501 | INHERITED FROM: lethal - all die before end of pupal stage || some die during larval stage || lethal - all die before end of first instar larval stage || lethal - all die before end of embryonic stage || cell shape defective || lethal - all die before end of larval stage |
| PDZ domain-like | 0.08324 | INHERITED FROM: cell polarity defective |
| Leucine zipper domain | 0.08639 | INHERITED FROM: increased mortality || developmental rate defective || lethal - all die before end of pupal stage || lethal - all die before end of first instar larval stage || lethal - all die before end of larval stage |
| Cyclin-like | 0.1007 | INHERITED FROM: mitotic cell cycle defective || cell cycle defective |
| Periplasmic binding protein-like II | 0.109 | INHERITED FROM: neurophysiology defective || feeding behavior defective || sensory perception defective |
| FYVE/PHD zinc finger | 0.1129 | INHERITED FROM: modifier of variegation |
| BRCT domain | 0.1171 | INHERITED FROM: radiation sensitive |
| EF-hand | 0.1184 | INHERITED FROM: flightless |
| SNARE fusion complex | 0.1362 | INHERITED FROM: uncoordinated || neurophysiology defective || increased mortality during development |
| Fibronectin type III | 0.1455 | INHERITED FROM: cell adhesion defective |
| beta-beta-alpha zinc fingers | 0.1725 | INHERITED FROM: visible |
| Concanavalin A-like lectins/glucanases | 0.198 | INHERITED FROM: cell polarity defective |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.2067 | INHERITED FROM: neurophysiology defective |
| N-acetylmuramoyl-L-alanine amidase-like | 0.218 | INHERITED FROM: immune response defective |
| Tudor/PWWP/MBT | 0.239 | INHERITED FROM: neoplasia || sterile |
| Cysteine proteinases | 0.2456 | INHERITED FROM: behavior defective |
| Chromo domain-like | 0.2669 | INHERITED FROM: suppressor of variegation || non-suppressor of variegation || modifier of variegation |
| Ankyrin repeat | 0.282 | INHERITED FROM: neurophysiology defective || behavior defective || thermotaxis behavior defective || temperature response defective || courtship behavior defective || chemosensitive behavior defective || sensory perception defective |
| HMG-box | 0.2884 | INHERITED FROM: visible |
| P-loop containing nucleoside triphosphate hydrolases | 0.3391 | INHERITED FROM: cell cycle defective |
| Macro domain-like | 0.3452 | INHERITED FROM: male sterile || sterile |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.377 | INHERITED FROM: chemical resistant || phototaxis defective |
| Nicotinic receptor ligand binding domain-like | 0.377 | INHERITED FROM: chemical resistant || phototaxis defective |
| SH2 domain | 0.3841 | INHERITED FROM: planar polarity defective || visible |
| Growth factor receptor domain | 0.4154 | INHERITED FROM: planar polarity defective || cell polarity defective |
| Voltage-gated potassium channels | 0.4154 | INHERITED FROM: circadian rhythm defective || chemical resistant || neurophysiology defective || behavior defective || chemical sensitive || chemosensitive behavior defective || sensory perception defective |
| Cystine-knot cytokines | 0.4607 | INHERITED FROM: circadian rhythm defective |
| POZ domain | 0.4608 | INHERITED FROM: sleep defective || body color defective |
| PAZ domain | 0.4679 | INHERITED FROM: mitotic cell cycle defective || suppressor of variegation || cell cycle defective || modifier of variegation |
| Tubulin nucleotide-binding domain-like | 0.523 | INHERITED FROM: cell cycle defective |
| Family A G protein-coupled receptor-like | 0.5304 | INHERITED FROM: hypoactive || mating defective || behavior defective |
| RNA-binding domain, RBD | 0.5446 | INHERITED FROM: lethal |
| Ribonuclease H-like | 0.5637 | INHERITED FROM: melanotic mass phenotype |
| Cadherin-like | 0.5929 | INHERITED FROM: cell polarity defective |
| cAMP-binding domain-like | 0.5929 | INHERITED FROM: hyperactive || chemical resistant || sensory perception defective |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.6138 | INHERITED FROM: visible |
| Immunoglobulin | 0.7179 | INHERITED FROM: cell migration defective |
| SET domain | 0.7221 | INHERITED FROM: suppressor of variegation || non-suppressor of variegation || modifier of variegation || homeotic |
| Nucleotide cyclase | 0.8353 | INHERITED FROM: taste perception defective |
| NAD(P)-binding Rossmann-fold domains | 0.9268 | INHERITED FROM: electrophoretic variant |
| alpha/beta-Hydrolases | 1 | INHERITED FROM: electrophoretic variant |
| Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
| Nucleoporin domain | 0 | Direct |
| 2Fe-2S ferredoxin-like | 0 | Direct |
| Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0 | Direct |
| SAND domain-like | 0 | Direct |
| GroEL-intermediate domain like | 0 | Direct |
| DNA/RNA polymerases | 0 | Direct |
| GroEL apical domain-like | 0 | Direct |
| C-terminal, gelsolin-like domain of Sec23/24 | 0 | Direct |
| Cu,Zn superoxide dismutase-like | 0 | Direct |
| Snake toxin-like | 0 | Direct |
| Activating enzymes of the ubiquitin-like proteins | 0 | Direct |
| PriA/YqbF domain | 0 | Direct |
| Aminoacid dehydrogenase-like, N-terminal domain | 0 | Direct |
| dsRNA-binding domain-like | 0 | Direct |
| DEK C-terminal domain | 0 | Direct |
| Clathrin adaptor appendage domain | 0 | Direct |
| Orange domain-like | 0 | Direct |
| ACP-like | 0 | Direct |
| Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
| N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Cysteine-rich DNA binding domain, (DM domain) | 0 | Direct |
| S15/NS1 RNA-binding domain | 0 | Direct |
| Ferredoxin reductase-like, C-terminal NADP-linked domain | 0 | Direct |
| RBP11-like subunits of RNA polymerase | 0 | Direct |
| Smc hinge domain | 0 | Direct |
| Spectrin repeat | 0 | Direct |
| C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
| Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
| 4Fe-4S ferredoxins | 0 | Direct |
| GINS helical bundle-like | 0 | Direct |
| ValRS/IleRS/LeuRS editing domain | 0 | Direct |
| Seven-hairpin glycosidases | 0 | Direct |
| Sm-like ribonucleoproteins | 0 | Direct |
| Ribosomal L27 protein-like | 0 | Direct |
| Isocitrate/Isopropylmalate dehydrogenase-like | 0 | Direct |
| L27 domain | 0 | Direct |
| Plexin repeat | 0 | Direct |
| Cytokine | 0 | Direct |
| L30e-like | 0 | Direct |
| Bet v1-like | 0 | Direct |
| Roadblock/LC7 domain | 0 | Direct |
| Prefoldin | 0 | Direct |
| Tropomyosin | 0 | Direct |
| Skp1 dimerisation domain-like | 0 | Direct |
| PX domain | 0 | Direct |
| Taf5 N-terminal domain-like | 0 | Direct |
| Succinyl-CoA synthetase domains | 0 | Direct |
| CBS-domain pair | 0 | Direct |
| Formin homology 2 domain (FH2 domain) | 0 | Direct |
| Riboflavin synthase domain-like | 0 | Direct |
| DEATH domain | 0 | Direct |
| RNase III domain-like | 0 | Direct |
| Class I glutamine amidotransferase-like | 0 | Direct |
| DNA-binding domain | 0 | Direct |
| Hormone receptor domain | 0 | Direct |
| CAD & PB1 domains | 0 | Direct |
| PreATP-grasp domain | 0 | Direct |
| GroEL equatorial domain-like | 0 | Direct |
| PIN domain-like | 0 | Direct |
| Class II aaRS ABD-related | 0 | Direct |
| vWA-like | 0 | Direct |
| Glutamine synthetase/guanido kinase | 0 | Direct |
| A DNA-binding domain in eukaryotic transcription factors | 0 | Direct |
| Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
| E2F-DP heterodimerization region | 0 | Direct |
| Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 0 | Direct |
| Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 0 | Direct |
| Zn-binding ribosomal proteins | 0 | Direct |
| Tetrahydrobiopterin biosynthesis enzymes-like | 0 | Direct |
| SMAD MH1 domain | 0 | Direct |
| HR1 repeat | 0 | Direct |
| Ribosomal protein S5 domain 2-like | 0 | Direct |
| beta and beta-prime subunits of DNA dependent RNA-polymerase | 0 | Direct |
| Sec1/munc18-like (SM) proteins | 0 | Direct |
| KA1-like | 0 | Direct |
| Mob1/phocein | 0 | Direct |
| Insulin-like | 0 | Direct |
| TIMP-like | 0 | Direct |
| Regulator of G-protein signaling, RGS | 0 | Direct |
| Putative DNA-binding domain | 0 | Direct |
| Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | 0 | Direct |
| FtsH protease domain-like | 0 | Direct |
| lambda repressor-like DNA-binding domains | 0 | Direct |
| Ferritin-like | 0 | Direct |
| HRDC-like | 0 | Direct |
| SAICAR synthase-like | 0 | Direct |
| Rudiment single hybrid motif | 0 | Direct |
| HLH, helix-loop-helix DNA-binding domain | 0 | Direct |
| Restriction endonuclease-like | 0 | Direct |
| JAB1/MPN domain | 0 | Direct |
| Aldolase | 0 | Direct |
| Aquaporin-like | 0 | Direct |
| ARID-like | 0 | Direct |
| Sema domain | 0 | Direct |
| SPOC domain-like | 0 | Direct |
| Zinc beta-ribbon | 0 | Direct |
| Retrovirus zinc finger-like domains | 0 | Direct |
| PapD-like | 0 | Direct |
| Translation proteins SH3-like domain | 0 | Direct |
| HSP90 C-terminal domain | 0 | Direct |
| Ribosomal protein L1 | 0 | Direct |
| TATA-box binding protein-like | 0 | Direct |
| Transducin (alpha subunit), insertion domain | 0 | Direct |
| SMAD/FHA domain | 0 | Direct |
| Blood coagulation inhibitor (disintegrin) | 0 | Direct |
| Ribonuclease PH domain 2-like | 0 | Direct |
| B-box zinc-binding domain | 0 | Direct |
| Caspase-like | 0 | Direct |
| PYP-like sensor domain (PAS domain) | 0 | Direct |
| Pectin lyase-like | 0 | Direct |
| Toll/Interleukin receptor TIR domain | 0 | Direct |
| Bromodomain | 0 | Direct |
| YVTN repeat-like/Quinoprotein amine dehydrogenase | 0 | Direct |
| ACT-like | 0 | Direct |
| Integrin domains | 0 | Direct |
| Sec7 domain | 0 | Direct |
| Periplasmic binding protein-like I | 0 | Direct |
| Terpenoid synthases | 0 | Direct |
| SNARE-like | 0 | Direct |
| SAP domain | 0 | Direct |
| Lipocalins | 0 | Direct |
| Nop domain | 0 | Direct |
| Nuclear receptor ligand-binding domain | 0 | Direct |
| Subtilisin-like | 0 | Direct |
| ThrRS/AlaRS common domain | 0 | Direct |
| Multidrug efflux transporter AcrB transmembrane domain | 0 | Direct |
| Translational machinery components | 0 | Direct |
| Homeodomain-like | 0.000003536 | Direct |
| ARM repeat | 0.00003195 | Direct |
| SH3-domain | 0.00007731 | Direct |
| Protein kinase-like (PK-like) | 0.0002821 | Direct |
| EGF/Laminin | 0.01358 | Inherited |
| Cysteine-rich domain | 0.06332 | Inherited |
| Nucleotidylyl transferase | 0.06332 | Inherited |
| p53-like transcription factors | 0.06332 | Inherited |
| beta-sandwich domain of Sec23/24 | 0.07501 | Inherited |
| PDZ domain-like | 0.08324 | Inherited |
| Leucine zipper domain | 0.08639 | Inherited |
| Cyclin-like | 0.1007 | Inherited |
| Periplasmic binding protein-like II | 0.109 | Inherited |
| FYVE/PHD zinc finger | 0.1129 | Inherited |
| BRCT domain | 0.1171 | Inherited |
| EF-hand | 0.1184 | Inherited |
| SNARE fusion complex | 0.1362 | Inherited |
| Fibronectin type III | 0.1455 | Inherited |
| beta-beta-alpha zinc fingers | 0.1725 | Inherited |
| Concanavalin A-like lectins/glucanases | 0.198 | Inherited |
| C2 domain (Calcium/lipid-binding domain, CaLB) | 0.2067 | Inherited |
| N-acetylmuramoyl-L-alanine amidase-like | 0.218 | Inherited |
| Tudor/PWWP/MBT | 0.239 | Inherited |
| Cysteine proteinases | 0.2456 | Inherited |
| Chromo domain-like | 0.2669 | Inherited |
| Ankyrin repeat | 0.282 | Inherited |
| HMG-box | 0.2884 | Inherited |
| P-loop containing nucleoside triphosphate hydrolases | 0.3391 | Inherited |
| Macro domain-like | 0.3452 | Inherited |
| Neurotransmitter-gated ion-channel transmembrane pore | 0.377 | Inherited |
| Nicotinic receptor ligand binding domain-like | 0.377 | Inherited |
| SH2 domain | 0.3841 | Inherited |
| Growth factor receptor domain | 0.4154 | Inherited |
| Voltage-gated potassium channels | 0.4154 | Inherited |
| Cystine-knot cytokines | 0.4607 | Inherited |
| POZ domain | 0.4608 | Inherited |
| PAZ domain | 0.4679 | Inherited |
| Tubulin nucleotide-binding domain-like | 0.523 | Inherited |
| Family A G protein-coupled receptor-like | 0.5304 | Inherited |
| RNA-binding domain, RBD | 0.5446 | Inherited |
| Ribonuclease H-like | 0.5637 | Inherited |
| Cadherin-like | 0.5929 | Inherited |
| cAMP-binding domain-like | 0.5929 | Inherited |
| Glucocorticoid receptor-like (DNA-binding domain) | 0.6138 | Inherited |
| Immunoglobulin | 0.7179 | Inherited |
| SET domain | 0.7221 | Inherited |
| Nucleotide cyclase | 0.8353 | Inherited |
| NAD(P)-binding Rossmann-fold domains | 0.9268 | Inherited |
| alpha/beta-Hydrolases | 1 | Inherited |
(show details)
Supra-domains annotated to this FP term (Not in SPFP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | DIRECT |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | DIRECT |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | DIRECT |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | DIRECT |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | DIRECT |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | DIRECT |
46785,54928
46785 - "Winged helix" DNA-binding domain
54928 - RNA-binding domain, RBD | 0 | DIRECT |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | DIRECT |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | DIRECT |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | DIRECT |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | DIRECT |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | DIRECT |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | DIRECT |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | DIRECT |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | DIRECT |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | DIRECT |
50615,52540
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | DIRECT |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | DIRECT |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | DIRECT |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | DIRECT |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | DIRECT |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | DIRECT |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | DIRECT |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0 | DIRECT |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | DIRECT |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | DIRECT |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | DIRECT |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | DIRECT |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | DIRECT |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | DIRECT |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | DIRECT |
111418,81321
111418 - Hormone receptor domain
81321 - Family A G protein-coupled receptor-like | 0 | DIRECT |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0 | DIRECT |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
54534,48452
54534 - FKBP-like
48452 - TPR-like | 0 | DIRECT |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | DIRECT |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | DIRECT |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | DIRECT |
57716,46689
57716 - Glucocorticoid receptor-like (DNA-binding domain)
46689 - Homeodomain-like | 0 | DIRECT |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0 | DIRECT |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0 | DIRECT |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | DIRECT |
55945,55945
55945 - TATA-box binding protein-like
55945 - TATA-box binding protein-like | 0 | DIRECT |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | DIRECT |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | DIRECT |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | DIRECT |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | DIRECT |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | DIRECT |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | DIRECT |
52949,53187
52949 - Macro domain-like
53187 - Zn-dependent exopeptidases | 0 | DIRECT |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | DIRECT |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | DIRECT |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.1639 | INHERITED FROM: cell migration defective || cell adhesion defective |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.2364 | INHERITED FROM: cell migration defective || cell adhesion defective |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.2476 | INHERITED FROM: cell migration defective || cell adhesion defective |
51045,51045
51045 - WW domain
51045 - WW domain | 0.2543 | INHERITED FROM: increased cell number |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.3452 | INHERITED FROM: chemosensitive behavior defective || sensory perception defective |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.377 | INHERITED FROM: chemical resistant || phototaxis defective |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.377 | INHERITED FROM: behavior defective || cell polarity defective |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.4002 | INHERITED FROM: increased occurrence of cell division || decreased occurrence of cell division || planar polarity defective || hyperplasia |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.4759 | INHERITED FROM: visible |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0.5483 | INHERITED FROM: mitotic cell cycle defective || suppressor of variegation || cell cycle defective || modifier of variegation |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.68 | INHERITED FROM: auditory perception defective || radiation sensitive || DNA repair defective |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.6906 | INHERITED FROM: cell polarity defective |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0.762 | INHERITED FROM: body size defective |
| Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
47459,55785
47459 - HLH, helix-loop-helix DNA-binding domain
55785 - PYP-like sensor domain (PAS domain) | 0 | Direct |
48425,50729
48425 - Sec7 domain
50729 - PH domain-like | 0 | Direct |
56059,52210
56059 - Glutathione synthetase ATP-binding domain-like
52210 - Succinyl-CoA synthetase domains | 0 | Direct |
54980,54211
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like | 0 | Direct |
101912,103575
101912 - Sema domain
103575 - Plexin repeat | 0 | Direct |
48371,56112
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
49265,49265
49265 - Fibronectin type III
49265 - Fibronectin type III | 0 | Direct |
46785,54928
46785 - "Winged helix" DNA-binding domain
54928 - RNA-binding domain, RBD | 0 | Direct |
46785,46785
46785 - "Winged helix" DNA-binding domain
46785 - "Winged helix" DNA-binding domain | 0 | Direct |
48592,54849
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like | 0 | Direct |
57850,57850
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
54236,47031
54236 - Ubiquitin-like
47031 - Second domain of FERM | 0 | Direct |
52058,52058
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
52540,140990
52540 - P-loop containing nucleoside triphosphate hydrolases
140990 - FtsH protease domain-like | 0 | Direct |
56059,51246
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
57889,57889
57889 - Cysteine-rich domain
57889 - Cysteine-rich domain | 0 | Direct |
57196,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
54768,54768
54768 - dsRNA-binding domain-like
54768 - dsRNA-binding domain-like | 0 | Direct |
56112,48371
56112 - Protein kinase-like (PK-like)
48371 - ARM repeat | 0 | Direct |
46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
46689,46689
46689 - Homeodomain-like
46689 - Homeodomain-like | 0 | Direct |
101288,50156
101288 - L27 domain
50156 - PDZ domain-like | 0 | Direct |
57903,57903
57903 - FYVE/PHD zinc finger
57903 - FYVE/PHD zinc finger | 0 | Direct |
50615,52540
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54211,55666
54211 - Ribosomal protein S5 domain 2-like
55666 - Ribonuclease PH domain 2-like | 0 | Direct |
63748,63748
63748 - Tudor/PWWP/MBT
63748 - Tudor/PWWP/MBT | 0 | Direct |
55550,56112
55550 - SH2 domain
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54791,54791
54791 - Eukaryotic type KH-domain (KH-domain type I)
54791 - Eukaryotic type KH-domain (KH-domain type I) | 0 | Direct |
46785,144074
46785 - "Winged helix" DNA-binding domain
144074 - E2F-DP heterodimerization region | 0 | Direct |
50044,55550
50044 - SH3-domain
55550 - SH2 domain | 0 | Direct |
50677,52374
50677 - ValRS/IleRS/LeuRS editing domain
52374 - Nucleotidylyl transferase | 0 | Direct |
52374,47323
52374 - Nucleotidylyl transferase
47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0 | Direct |
57716,48508
57716 - Glucocorticoid receptor-like (DNA-binding domain)
48508 - Nuclear receptor ligand-binding domain | 0 | Direct |
50156,50044
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
53223,51735
53223 - Aminoacid dehydrogenase-like, N-terminal domain
51735 - NAD(P)-binding Rossmann-fold domains | 0 | Direct |
55681,52954
55681 - Class II aaRS and biotin synthetases
52954 - Class II aaRS ABD-related | 0 | Direct |
54695,81382
54695 - POZ domain
81382 - Skp1 dimerisation domain-like | 0 | Direct |
53067,100920
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
49265,48726
49265 - Fibronectin type III
48726 - Immunoglobulin | 0 | Direct |
50978,50978
50978 - WD40 repeat-like
50978 - WD40 repeat-like | 0 | Direct |
49562,48371
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat | 0 | Direct |
55486,57552
55486 - Metalloproteases ("zincins"), catalytic domain
57552 - Blood coagulation inhibitor (disintegrin) | 0 | Direct |
111418,81321
111418 - Hormone receptor domain
81321 - Family A G protein-coupled receptor-like | 0 | Direct |
52058,48726
52058 - L domain-like
48726 - Immunoglobulin | 0 | Direct |
52540,47917
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
54534,48452
54534 - FKBP-like
48452 - TPR-like | 0 | Direct |
49899,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin | 0 | Direct |
55550,50044
55550 - SH2 domain
50044 - SH3-domain | 0 | Direct |
52113,52113
52113 - BRCT domain
52113 - BRCT domain | 0 | Direct |
57716,46689
57716 - Glucocorticoid receptor-like (DNA-binding domain)
46689 - Homeodomain-like | 0 | Direct |
49417,81296
49417 - p53-like transcription factors
81296 - E set domains | 0 | Direct |
55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
47459,158457
47459 - HLH, helix-loop-helix DNA-binding domain
158457 - Orange domain-like | 0 | Direct |
50044,52540
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55021,56534
55021 - ACT-like
56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 0 | Direct |
55945,55945
55945 - TATA-box binding protein-like
55945 - TATA-box binding protein-like | 0 | Direct |
47413,46689
47413 - lambda repressor-like DNA-binding domains
46689 - Homeodomain-like | 0 | Direct |
54211,54980
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
52440,56059
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like | 0 | Direct |
47954,47954
47954 - Cyclin-like
47954 - Cyclin-like | 0 | Direct |
57903,47370
57903 - FYVE/PHD zinc finger
47370 - Bromodomain | 0 | Direct |
57184,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
100920,100934
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
50044,50044
50044 - SH3-domain
50044 - SH3-domain | 0 | Direct |
81383,52047
81383 - F-box domain
52047 - RNI-like | 0 | Direct |
52949,53187
52949 - Macro domain-like
53187 - Zn-dependent exopeptidases | 0 | Direct |
47895,52540
47895 - Transducin (alpha subunit), insertion domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54849,52029
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
57196,49854
57196 - EGF/Laminin
49854 - Spermadhesin, CUB domain | 0 | Direct |
57184,57184
57184 - Growth factor receptor domain
57184 - Growth factor receptor domain | 0 | Direct |
57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.1639 | Inherited |
48726,49265
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.2364 | Inherited |
48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.2476 | Inherited |
51045,51045
51045 - WW domain
51045 - WW domain | 0.2543 | Inherited |
48403,48403
48403 - Ankyrin repeat
48403 - Ankyrin repeat | 0.3452 | Inherited |
63712,90112
63712 - Nicotinic receptor ligand binding domain-like
90112 - Neurotransmitter-gated ion-channel transmembrane pore | 0.377 | Inherited |
49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0.377 | Inherited |
57196,57184
57196 - EGF/Laminin
57184 - Growth factor receptor domain | 0.4002 | Inherited |
57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.4759 | Inherited |
101690,53098
101690 - PAZ domain
53098 - Ribonuclease H-like | 0.5483 | Inherited |
52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.68 | Inherited |
49313,49313
49313 - Cadherin-like
49313 - Cadherin-like | 0.6906 | Inherited |
57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0.762 | Inherited |
(show details)
Supra-domains annotated to this FP term (Not in SPFP)
Highlighted in gray are those with FDR>0.001
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | DIRECT |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | DIRECT |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | DIRECT |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | DIRECT |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | DIRECT |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | DIRECT |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | DIRECT |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0 | DIRECT |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
55753,55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | DIRECT |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | DIRECT |
50615,52540,47917
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | DIRECT |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | DIRECT |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | DIRECT |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | DIRECT |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | DIRECT |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | DIRECT |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | DIRECT |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.04627 | INHERITED FROM: cell migration defective |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.1362 | INHERITED FROM: cell adhesion defective |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.1362 | INHERITED FROM: some die during embryonic stage || cell migration defective || planar polarity defective || cell polarity defective || cell adhesion defective || lethal - all die before end of first instar larval stage || size defective || lethal - all die before end of embryonic stage |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2966 | INHERITED FROM: auditory perception defective || sensory perception defective |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0.4679 | INHERITED FROM: body size defective || size defective |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.7337 | INHERITED FROM: cell polarity defective |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.8781 | INHERITED FROM: visible |
| Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
57196,49899,49899
57196 - EGF/Laminin
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
49265,48726,48726
49265 - Fibronectin type III
48726 - Immunoglobulin
48726 - Immunoglobulin | 0 | Direct |
49562,48371,56112
49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
48371 - ARM repeat
56112 - Protein kinase-like (PK-like) | 0 | Direct |
54236,47031,50729
54236 - Ubiquitin-like
47031 - Second domain of FERM
50729 - PH domain-like | 0 | Direct |
48592,54849,52029
48592 - GroEL equatorial domain-like
54849 - GroEL-intermediate domain like
52029 - GroEL apical domain-like | 0 | Direct |
53067,53067,100920
53067 - Actin-like ATPase domain
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain | 0 | Direct |
57196,57184,57196
57196 - EGF/Laminin
57184 - Growth factor receptor domain
57196 - EGF/Laminin | 0 | Direct |
48452,48452,48452
48452 - TPR-like
48452 - TPR-like
48452 - TPR-like | 0 | Direct |
57850,57850,57850
57850 - RING/U-box
57850 - RING/U-box
57850 - RING/U-box | 0 | Direct |
50156,50044,52540
50156 - PDZ domain-like
50044 - SH3-domain
52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
55753,55753,55753
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins
55753 - Actin depolymerizing proteins | 0 | Direct |
101288,50156,50044
101288 - L27 domain
50156 - PDZ domain-like
50044 - SH3-domain | 0 | Direct |
50615,52540,47917
50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
52540 - P-loop containing nucleoside triphosphate hydrolases
47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
81296,81296,81296
81296 - E set domains
81296 - E set domains
81296 - E set domains | 0 | Direct |
52440,56059,51246
52440 - PreATP-grasp domain
56059 - Glutathione synthetase ATP-binding domain-like
51246 - Rudiment single hybrid motif | 0 | Direct |
49899,49899,49899
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases
49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
53067,100920,100934
53067 - Actin-like ATPase domain
100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain | 0 | Direct |
54980,54211,54980
54980 - EF-G C-terminal domain-like
54211 - Ribosomal protein S5 domain 2-like
54980 - EF-G C-terminal domain-like | 0 | Direct |
57184,57196,57196
57184 - Growth factor receptor domain
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
49899,57196,57196
49899 - Concanavalin A-like lectins/glucanases
57196 - EGF/Laminin
57196 - EGF/Laminin | 0 | Direct |
46966,46966,46966
46966 - Spectrin repeat
46966 - Spectrin repeat
46966 - Spectrin repeat | 0 | Direct |
52058,52058,52058
52058 - L domain-like
52058 - L domain-like
52058 - L domain-like | 0 | Direct |
48726,48726,49265
48726 - Immunoglobulin
48726 - Immunoglobulin
49265 - Fibronectin type III | 0.04627 | Inherited |
48726,48726,48726
48726 - Immunoglobulin
48726 - Immunoglobulin
48726 - Immunoglobulin | 0.1362 | Inherited |
57196,57196,57196
57196 - EGF/Laminin
57196 - EGF/Laminin
57196 - EGF/Laminin | 0.1362 | Inherited |
52540,52540,52540
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases
52540 - P-loop containing nucleoside triphosphate hydrolases | 0.2966 | Inherited |
57625,57625,57625
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins
57625 - Invertebrate chitin-binding proteins | 0.4679 | Inherited |
49313,49313,49313
49313 - Cadherin-like
49313 - Cadherin-like
49313 - Cadherin-like | 0.7337 | Inherited |
57667,57667,57667
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers
57667 - beta-beta-alpha zinc fingers | 0.8781 | Inherited |
Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
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