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Phenotypic Abnormality (PA): Abnormality of skull size

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + + 4:   Abnormality of the skeletal system [HP:0000924] <7>(88|98) (93|55|34)
+ + + 3:   Abnormality of head or neck [HP:0000152] <2>(86|104) (97|58|38)
+ + + 3:   Abnormality of skeletal morphology [HP:0011842] <17>(86|89) (90|52|33)
+ + 2:   Abnormal axial skeleton morphology [HP:0009121] <6>(47|61) (51|30|26)
+ + 2:   Abnormality of the head [HP:0000234] <6>(85|102) (96|57|38)
+ 1:   Abnormal skull morphology [HP:0000929] <14>(25|38) (28|22|20)
0:   Abnormality of skull size [HP:0000240] <2>(14|23) (15|11|5)
- 1:   Decreased head circumference [HP:0040195] <2>(7|13) (8|5|1)
- 1:   Increased head circumference [HP:0040194] <1>(3|5) (3|5|4)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
C-terminal, gelsolin-like domain of Sec23/240Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Acyl-CoA N-acyltransferases (Nat)0Direct
Restriction endonuclease-like0Direct
RuvA domain 2-like0Direct
Helical domain of Sec23/240Direct
Pseudouridine synthase0Direct
4Fe-4S ferredoxins0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
Zn-finger domain of Sec23/240Direct
BRK domain-like0Direct
NagB/RpiA/CoA transferase-like0.08552Inherited
Nucleotide-diphospho-sugar transferases0.2056Inherited
Ribonuclease H-like0.2976Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
Ferredoxin domains from multidomain proteins0Direct
Protein serine/threonine phosphatase0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Helical domain of Sec23/240Direct
N-acetyl transferase, NAT0Direct
Clathrin adaptor core protein0Direct
BRK domain-like0Direct
SWIRM domain0Direct
tRNA-intron endonuclease catalytic domain-like0Direct
XPF/Rad1/Mus81 nuclease0Direct
Histone deacetylase, HDAC0Direct
Exostosin0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
beta-sandwich domain of Sec23/240Direct
Trunk domain of Sec23/240Direct
IF2B-like0Direct
Histone lysine methyltransferases0.00003082Direct
Elongation factors0.001737Inherited
ARID domain0.003095Inherited
PHD domain0.02389Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.02748Inherited
Bromodomain0.02748Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Acyl-CoA N-acyltransferases (Nat)0Direct
BRK domain-like0Direct
Pseudouridine synthase0Direct
Restriction endonuclease-like0Direct
RuvA domain 2-like0Direct
Helical domain of Sec23/240Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Zn-finger domain of Sec23/240Direct
4Fe-4S ferredoxins0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
tRNA-intron endonuclease catalytic domain-like0Direct
Bromodomain0.03265Inherited
NagB/RpiA/CoA transferase-like0.06628Inherited
Nucleotide-diphospho-sugar transferases0.1724Inherited
Ribonuclease H-like0.2579Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    81995,81811
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    53300,81995
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 0Direct
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.002116Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.003605Inherited
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.003605Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    53300,81995,81811
  • 53300 - vWA-like
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 0Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    81995,81811,82754
  • 81995 - beta-sandwich domain of Sec23/24
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.003605Inherited
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.003605Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)