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Phenotypic Abnormality (PA): Atrophy/Degeneration affecting the cerebrum

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Phenotypic abnormality [HP:0000118] <25>
+ + + + 4:   Abnormality of the nervous system [HP:0000707] <4>(142|168) (156|103|45)
+ + + 3:   Abnormality of nervous system morphology [HP:0012639] <5>(69|97) (79|52|16)
+ + 2:   Abnormality of brain morphology [HP:0012443] <13>(43|63) (53|34|15)
+ + 2:   Abnormality of forebrain morphology [HP:0100547] <6>(26|32) (30|18|5)
+ + 2:   Morphological abnormality of the central nervous system [HP:0002011] <17>(60|85) (69|44|16)
+ + 2:   Atrophy/Degeneration affecting the central nervous system [HP:0007367] <10>(3|5) (5|3|0)
+ 1:   Aplasia/Hypoplasia involving the central nervous system [HP:0002977] <13>(19|26) (23|13|3)
+ 1:   Brain atrophy [HP:0012444] <3>(1|3) (3|2|0)
+ 1:   Abnormality of the cerebrum [HP:0002060] <16>(25|31) (29|18|5)
0:   Atrophy/Degeneration affecting the cerebrum [HP:0007369] <5>(1|3) (3|2|0)
- 1:   Cerebral atrophy [HP:0002059] <4>(0|2) (1|0|0)
- 1:   Subcortical cerebral atrophy [HP:0012157] <1>(1|1) (2|2|0)
- 1:   Cerebral cortical neurodegeneration [HP:0006964](0|0) (0|0|0)
- 1:   Cerebral degeneration [HP:0007313](0|0) (0|0|0)
- 1:   Corpus callosum atrophy [HP:0007371](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Actin-like ATPase domain0.05261Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.01892Inherited
Clathrin adaptor core protein0.01963Inherited
PDZ domain0.05493Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PDZ domain-like0.01342Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.03897Inherited
Actin-like ATPase domain0.03897Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.07131Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.1242Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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