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Phenotypic Abnormality (PA): Aplasia/hypoplasia of the extremities

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Abnormality of the skeletal system [HP:0000924] <7>(88|98) (93|55|34)
+ + 2:   Abnormality of skeletal morphology [HP:0011842] <17>(86|89) (90|52|33)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of limbs [HP:0040064] <8>(58|66) (63|33|25)
+ 1:   Aplasia/hypoplasia involving the skeleton [HP:0009115] <2>(13|12) (15|10|17)
0:   Aplasia/hypoplasia of the extremities [HP:0009815] <6>(8|10) (10|3|5)
- 1:   Limb undergrowth [HP:0009826] <8>(1|1) (1|0|0)
- 1:   Amelia [HP:0009827] <3>(0|0) (0|0|0)
- 1:   Aplasia/hypoplasia involving bones of the extremities [HP:0045060] <3>(7|9) (9|3|5)
- 1:   Phocomelia [HP:0009829] <3>(0|0) (0|0|0)
- 1:   Acromelia [HP:0010884] <2>(0|0) (0|0|0)
- 1:   Peromelia [HP:0009828] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
ARID-like0.002865Inherited
Arginase/deacetylase0.003814Inherited
Multidrug efflux transporter AcrB transmembrane domain0.01197Inherited
RuvA domain 2-like0.04414Inherited
BRK domain-like0.04414Inherited
HMG-box0.04845Inherited
p53-like transcription factors0.05465Inherited
Immunoglobulin0.6872Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
SWIRM domain0Direct
Histone deacetylase, HDAC0Direct
ARID domain0.001691Inherited
BRK domain-like0.03438Inherited
Notch domain0.03438Inherited
HMG-box0.03913Inherited
RecA protein-like (ATPase-domain)0.04309Inherited
Transforming growth factor (TGF)-beta0.3411Inherited
I set domains0.4379Inherited
Homeodomain0.5197Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
ARID-like0.001655Inherited
Arginase/deacetylase0.002254Inherited
Multidrug efflux transporter AcrB transmembrane domain0.007805Inherited
BRK domain-like0.03204Inherited
Notch domain0.03204Inherited
RuvA domain 2-like0.03204Inherited
HMG-box0.03555Inherited
p53-like transcription factors0.0406Inherited
Cystine-knot cytokines0.4574Inherited
Immunoglobulin0.6479Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.01286Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.03877Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.7145Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.01286Inherited
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.01815Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.01982Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.5438Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)