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Phenotypic Abnormality (PA): Abnormal vascular morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the cardiovascular system [HP:0001626] <5>(60|88) (73|43|30)
+ 1:   Abnormality of cardiovascular system morphology [HP:0030680] <3>(29|42) (31|19|20)
+ 1:   Abnormality of the vasculature [HP:0002597] <13>(35|56) (45|27|18)
0:   Abnormal vascular morphology [HP:0025015] <12>(15|18) (16|11|10)
- 1:   Abnormal systemic arterial morphology [HP:0011004] <24>(8|11) (9|4|2)
- 1:   Abnormal venous morphology [HP:0002624] <9>(1|1) (1|0|0)
- 1:   Arteriovenous malformation [HP:0100026] <8>(0|1) (0|0|0)
- 1:   Dilatation [HP:0002617] <6>(4|5) (4|5|6)
- 1:   Vasculitis [HP:0002633] <6>(4|3) (4|2|0)
- 1:   Abnormal lymphatic vessel morphology [HP:0100766] <5>(0|0) (0|0|0)
- 1:   Abnormal morphology of the great vessels [HP:0030962] <5>(5|7) (6|4|6)
- 1:   Perivascular fibrosis [HP:0032200] <1>(0|0) (0|0|0)
- 1:   Vascular calcification [HP:0004934] <1>(0|0) (0|0|0)
- 1:   Vascular tortuosity [HP:0004948] <1>(0|0) (0|0|0)
- 1:   Abnormal capillary morphology [HP:0025016](0|0) (0|0|0)
- 1:   Abnormal vasa vasorum morphology [HP:0031465](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
p53-like transcription factors0.0009305Direct
Snake toxin-like0.02808Inherited
FnI-like domain0.06022Inherited
Notch domain0.07125Inherited
SMAD MH1 domain0.07125Inherited
DEATH domain0.1218Inherited
TB module/8-cys domain0.1642Inherited
Myosin rod fragments0.1686Inherited
(Trans)glycosidases0.1934Inherited
SMAD/FHA domain0.3146Inherited
RNI-like0.3427Inherited
TNF receptor-like0.3427Inherited
MHC antigen-recognition domain0.3749Inherited
Tropomyosin0.3749Inherited
Actin-like ATPase domain0.595Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Growth factor receptor domain0.0003571Direct
DEATH domain, DD0.004167Inherited
Extracellular domain of cell surface receptors0.004276Inherited
Double-stranded RNA-binding domain (dsRBD)0.004935Inherited
VWC domain0.0104Inherited
Transforming growth factor (TGF)-beta0.05078Inherited
Notch domain0.05623Inherited
SMAD MH1 domain0.05623Inherited
SMAD domain0.05623Inherited
TB module/8-cys domain0.1381Inherited
Myosin rod fragments0.1418Inherited
RecA protein-like (ATPase-domain)0.1418Inherited
Actin/HSP700.2208Inherited
ABC transporter ATPase domain-like0.297Inherited
Tropomyosin0.3385Inherited
MHC antigen-recognition domain0.3385Inherited
Erythroid transcription factor GATA-10.3385Inherited
C1 set domains (antibody constant domain-like)0.5362Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53-like transcription factors0.000492Direct
Snake toxin-like0.0196Inherited
FnI-like domain0.04521Inherited
Notch domain0.05435Inherited
SMAD MH1 domain0.05435Inherited
DEATH domain0.09716Inherited
TB module/8-cys domain0.1346Inherited
Myosin rod fragments0.1387Inherited
(Trans)glycosidases0.1612Inherited
SMAD/FHA domain0.2739Inherited
TNF receptor-like0.3012Inherited
RNI-like0.3012Inherited
Tropomyosin0.332Inherited
MHC antigen-recognition domain0.332Inherited
Actin-like ATPase domain0.5523Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.6196Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    49562,48350
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48350 - GTPase activation domain, GAP
  • 0Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.004566Inherited
    57196,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.01297Inherited
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.05435Inherited
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.1346Inherited
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.1346Inherited
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.2159Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.332Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.4337Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.4727Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57184,57184
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.01166Inherited
    57196,57196,57184
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.02471Inherited
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.05435Inherited
    57184,57184,57196
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.05435Inherited
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.05435Inherited
    57196,57184,57196
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.07291Inherited
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.1346Inherited
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1346Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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