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Phenotypic Abnormality (PA): Abnormality of lower limb joint

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the skeletal system [HP:0000924] <7>(88|98) (93|55|34)
+ + 2:   Abnormality of skeletal morphology [HP:0011842] <17>(86|89) (90|52|33)
+ + 2:   Abnormality of limbs [HP:0040064] <8>(58|66) (63|33|25)
+ 1:   Abnormal joint morphology [HP:0001367] <18>(19|23) (20|9|2)
+ 1:   Abnormality of the lower limb [HP:0002814] <17>(31|34) (35|15|13)
0:   Abnormality of lower limb joint [HP:0100491] <5>(10|13) (11|2|1)
- 1:   Abnormality of the knee [HP:0002815] <15>(4|4) (4|1|1)
- 1:   Abnormality of the ankles [HP:0003028] <9>(2|1) (2|1|0)
- 1:   Abnormality of the hip joint [HP:0001384] <5>(5|9) (6|2|0)
- 1:   Synostosis involving bones of the lower limbs [HP:0009138] <3>(1|0) (1|0|0)
- 1:   Joint contractures involving the joints of the feet [HP:0100492] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
RuvA domain 2-like0Direct
Restriction endonuclease-like0.002866Inherited
SNARE fusion complex0.009124Inherited
Tropomyosin0.009582Inherited
ARID-like0.05612Inherited
SET domain0.07129Inherited
Bromodomain0.0742Inherited
vWA-like0.1426Inherited
Cystine-knot cytokines0.2353Inherited
Voltage-gated potassium channels0.7453Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Filamin repeat (rod domain)0Direct
XPF/Rad1/Mus81 nuclease0Direct
Histone lysine methyltransferases0.003335Inherited
Clathrin adaptor core protein0.006138Inherited
SNARE fusion complex0.006138Inherited
Tropomyosin0.006511Inherited
VWC domain0.01938Inherited
ARID domain0.04424Inherited
Myosin rod fragments0.05734Inherited
RecA protein-like (ATPase-domain)0.05734Inherited
Bromodomain0.06097Inherited
Integrin A (or I) domain0.06133Inherited
Inositol polyphosphate 5-phosphatase (IPP5)0.112Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
RuvA domain 2-like0Direct
Restriction endonuclease-like0.001656Inherited
SNARE fusion complex0.005838Inherited
Tropomyosin0.006147Inherited
ARID-like0.04184Inherited
Myosin rod fragments0.05402Inherited
SET domain0.05438Inherited
Bromodomain0.0568Inherited
vWA-like0.1159Inherited
Cystine-knot cytokines0.1996Inherited
Voltage-gated potassium channels0.7078Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.04184Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.04184Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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