SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Phenotypic Abnormality (PA): Abnormality of vision

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Phenotypic abnormality [HP:0000118] <25>
+ + 2:   Abnormality of the eye [HP:0000478] <2>(64|78) (69|38|28)
+ 1:   Abnormal eye physiology [HP:0012373] <17>(34|47) (37|22|20)
0:   Abnormality of vision [HP:0000504] <15>(4|16) (9|8|8)
- 1:   Abnormal contrast sensitivity [HP:0032036] <5>(0|0) (0|0|0)
- 1:   Visual impairment [HP:0000505] <4>(0|8) (3|6|7)
- 1:   Color vision defect [HP:0000551] <3>(2|2) (2|0|0)
- 1:   Nyctalopia [HP:0000662] <3>(0|0) (0|1|0)
- 1:   Abnormality of binocular vision [HP:0011514] <2>(0|0) (2|1|0)
- 1:   Difficulty adjusting to changes in luminance [HP:0030512] <2>(0|0) (0|0|0)
- 1:   Blurred vision [HP:0000622] <1>(0|0) (0|0|0)
- 1:   Vitreous floaters [HP:0100832] <1>(0|0) (0|0|0)
- 1:   Amaurosis fugax [HP:0100576](2|2) (2|1|0)
- 1:   Bradyopsia [HP:0030511](0|0) (0|0|0)
- 1:   Hemeralopia [HP:0012047](0|0) (0|0|0)
- 1:   Metamorphopsia [HP:0012508](0|0) (0|0|0)
- 1:   Photophobia [HP:0000613](1|3) (1|0|0)
- 1:   Photopsia [HP:0030786](0|0) (0|0|0)
- 1:   Poor visual behavior for age [HP:0025152](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.08009Inherited
cAMP-binding domain-like0.09542Inherited
Family A G protein-coupled receptor-like0.3615Inherited
Ribosomal protein S5 domain 2-like0.5053Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Ferredoxin domains from multidomain proteins0Direct
Clathrin adaptor core protein0Direct
Glycosyl transferases group 10Direct
XPF/Rad1/Mus81 nuclease0Direct
IF2B-like0Direct
DNA gyrase/MutL, second domain0.005594Inherited
DNA gyrase/MutL, N-terminal domain0.005594Inherited
GAF domain0.0172Inherited
Pyrin domain, PYD0.04859Inherited
28-residue LRR0.06263Inherited
cAMP-binding domain0.1115Inherited
Fibroblast growth factors (FGF)0.2341Inherited
Rhodopsin-like0.2716Inherited
PDZ domain0.3235Inherited
G proteins0.4117Inherited
Phosphate binding protein-like0.6463Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GAF domain-like0.0176Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.0617Inherited
cAMP-binding domain-like0.07461Inherited
Family A G protein-coupled receptor-like0.3192Inherited
Nicotinic receptor ligand binding domain-like0.3775Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.3775Inherited
Ribosomal protein S5 domain 2-like0.461Inherited
PDZ domain-like0.5036Inherited
Periplasmic binding protein-like II0.6417Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0.005814Inherited
    55781,109604
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0176Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.0176Inherited
    50156,50156
  • 50156 - PDZ domain-like
  • 50156 - PDZ domain-like
  • 0.2334Inherited
    49899,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.2472Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.3775Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57581,57196
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0Direct
    57196,57196,57581
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0Direct
    49899,57196,49899
  • 49899 - Concanavalin A-like lectins/glucanases
  • 57196 - EGF/Laminin
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    141072,141072,141072
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 141072 - CalX-like
  • 0Direct
    57196,57581,57184
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.002548Inherited
    55781,55781,109604
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 109604 - HD-domain/PDEase-like
  • 0.0176Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.3292Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)