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Phenotypic Abnormality (PA): Abnormality of skin pigmentation

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the integument [HP:0001574] <4>(48|69) (59|37|15)
+ + 2:   Abnormality of the skin [HP:0000951] <4>(34|55) (45|36|12)
+ 1:   Abnormality of skin morphology [HP:0011121] <22>(29|49) (40|31|11)
0:   Abnormality of skin pigmentation [HP:0001000] <17>(2|8) (4|2|0)
- 1:   Hypopigmentation of the skin [HP:0001010] <9>(0|0) (0|0|0)
- 1:   Hyperpigmentation of the skin [HP:0000953] <6>(0|2) (0|0|0)
- 1:   Melanocytic nevus [HP:0000995] <4>(0|1) (0|0|0)
- 1:   Abnormality of dermal melanosomes [HP:0011125] <3>(0|0) (0|0|0)
- 1:   Freckling [HP:0001480] <2>(0|0) (0|0|0)
- 1:   Mottled pigmentation [HP:0001070] <2>(0|0) (0|0|0)
- 1:   Vitiligo [HP:0001045] <1>(0|0) (0|0|0)
- 1:   Blotching pigmentation of the skin [HP:0007610](0|0) (0|0|0)
- 1:   Depigmentation/hyperpigmentation of skin [HP:0007483](0|0) (0|0|0)
- 1:   Fine, reticulate skin pigmentation [HP:0007617](0|0) (0|0|0)
- 1:   Numerous pigmented freckles [HP:0007587](0|0) (0|0|0)
- 1:   Perioral hyperpigmentation [HP:0010802](0|0) (0|0|0)
- 1:   Periorbital hyperpigmentation [HP:0001106](0|0) (0|0|0)
- 1:   Pigmentation anomalies of sun-exposed skin [HP:0007623](0|0) (0|0|0)
- 1:   Profuse pigmented skin lesions [HP:0005587](0|0) (0|0|0)
- 1:   Reticulated skin pigmentation [HP:0007427](1|1) (1|0|0)
- 1:   Symmetric great toe depigmentation [HP:0200015](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
Intermediate filament protein, coiled coil region0.8798Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
C-terminal, gelsolin-like domain of Sec23/240.000802Direct
Helical domain of Sec23/240.000802Direct
beta-sandwich domain of Sec23/240.000802Direct
Trunk domain of Sec23/240.000802Direct
RecA protein-like (ATPase-domain)0.007817Inherited
Ras-binding domain, RBD0.01703Inherited
Intermediate filament protein, coiled coil region0.8695Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Zn-finger domain of Sec23/240Direct
Helical domain of Sec23/240.0006652Direct
C-terminal, gelsolin-like domain of Sec23/240.0006652Direct
Intermediate filament protein, coiled coil region0.8494Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.0006652Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)