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Phenotypic Abnormality (PA): Joint hypermobility

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the skeletal system [HP:0000924] <7>(88|98) (93|55|34)
+ + 2:   Abnormality of skeletal physiology [HP:0011843] <8>(17|23) (17|15|15)
+ 1:   Abnormality of joint mobility [HP:0011729] <6>(16|21) (16|15|15)
0:   Joint hypermobility [HP:0001382] <8>(5|9) (5|3|1)
- 1:   Finger joint hypermobility [HP:0006094] <2>(1|1) (1|1|0)
- 1:   Hyperextensible hand joints [HP:0005639] <1>(0|0) (0|0|0)
- 1:   Hypermobility of interphalangeal joints [HP:0005620] <1>(0|0) (0|0|0)
- 1:   Hip joint hypermobility [HP:0045087](0|0) (0|0|0)
- 1:   Hyperextensibility at elbow [HP:0010485](0|0) (0|0|0)
- 1:   Hyperextensibility at wrists [HP:0005072](1|1) (1|1|0)
- 1:   Joint hyperflexibility [HP:0005692](3|7) (3|2|1)
- 1:   Knee joint hypermobility [HP:0045086](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
C-terminal, gelsolin-like domain of Sec23/240.0003412Direct
Helical domain of Sec23/240.0003412Direct
Bromodomain0.0006223Direct
vWA-like0.01598Inherited
ARID-like0.03412Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
C-terminal, gelsolin-like domain of Sec23/240.0002206Direct
Helical domain of Sec23/240.0002206Direct
beta-sandwich domain of Sec23/240.0002206Direct
Trunk domain of Sec23/240.0002206Direct
Bromodomain0.0004517Direct
VWC domain0.01058Inherited
ARID domain0.02769Inherited
Ras-binding domain, RBD0.02769Inherited
Integrin A (or I) domain0.09654Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Helical domain of Sec23/240.000169Direct
C-terminal, gelsolin-like domain of Sec23/240.000169Direct
Bromodomain0.0003192Direct
vWA-like0.01067Inherited
ARID-like0.02425Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0.000169Direct
    53300,53300
  • 53300 - vWA-like
  • 53300 - vWA-like
  • 0.0006879Direct
    57184,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 0.05955Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57196,57184
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57184 - Growth factor receptor domain
  • 0.02425Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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