SUPERFAMILY 1.75 HMM library and genome assignments server

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Phenotypic Abnormality (PA): Mitral valve prolapse

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   Phenotypic abnormality [HP:0000118] <25>
+ + + + + + 6:   Abnormality of the cardiovascular system [HP:0001626] <5>(60|88) (73|43|30)
+ + + + + 5:   Abnormality of cardiovascular system morphology [HP:0030680] <3>(29|42) (31|19|20)
+ + + + 4:   Abnormal heart morphology [HP:0001627] <16>(20|35) (24|16|20)
+ + + 3:   Abnormal heart valve morphology [HP:0001654] <4>(5|11) (6|10|11)
+ + 2:   Abnormal atrioventricular valve morphology [HP:0006705] <3>(4|5) (4|6|8)
+ 1:   Abnormal mitral valve morphology [HP:0001633] <10>(4|5) (4|6|8)
0:   Mitral valve prolapse [HP:0001634] <1>(2|2) (2|4|6)
- 1:   Myxomatous mitral valve degeneration [HP:0004764](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
FnI-like domain0.000007928Direct
TB module/8-cys domain0.00002238Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
VWC domain0.00000117Direct
TB module/8-cys domain0.00001287Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
FnI-like domain0.000003297Direct
TB module/8-cys domain0.000009709Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57581,57184
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57184,57581
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.000002074Direct
    57581,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.000009709Direct
    57196,57581
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.000009709Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57184,57581,57184
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    57581,57184,57581
  • 57581 - TB module/8-cys domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0Direct
    57184,57581,57196
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 0.000002074Direct
    57184,57184,57581
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 57581 - TB module/8-cys domain
  • 0.000002074Direct
    57581,57196,57581
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57581 - TB module/8-cys domain
  • 0.000009709Direct
    57581,57196,57196
  • 57581 - TB module/8-cys domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000009709Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)