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Phenotypic Abnormality (PA): Hyperammonemia

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Phenotypic abnormality [HP:0000118] <25>
+ + + + 4:   Abnormality of metabolism/homeostasis [HP:0001939] <16>(75|82) (79|40|16)
+ + + 3:   Abnormal circulating metabolite concentration [HP:0032180] <12>(30|31) (31|14|4)
+ + 2:   Abnormal circulating nitrogen compound concentration [HP:0004364] <10>(7|7) (7|3|1)
+ 1:   Azotemia [HP:0002157] <5>(7|7) (7|3|1)
0:   Hyperammonemia [HP:0001987] <2>(6|5) (6|2|0)
- 1:   Acute hyperammonemia [HP:0008281](0|0) (0|0|0)
- 1:   Asymptomatic hyperammonemia [HP:0008162](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PreATP-grasp domain0.000001633Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.0000055Direct
Acyl-CoA dehydrogenase NM domain-like0.0000055Direct
Glutathione synthetase ATP-binding domain-like0.000009123Direct
Mitochondrial carrier0.00007712Direct
ClpP/crotonase0.0003044Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
BC N-terminal domain-like0.00000004645Direct
BC ATP-binding domain-like0.00000004645Direct
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.0000008849Direct
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.0000008849Direct
Mitochondrial carrier0.00004496Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PreATP-grasp domain0.0000006561Direct
Acyl-CoA dehydrogenase NM domain-like0.000002279Direct
Acyl-CoA dehydrogenase C-terminal domain-like0.000002279Direct
Glutathione synthetase ATP-binding domain-like0.000003812Direct
Mitochondrial carrier0.00003521Direct
ClpP/crotonase0.0001499Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.0000002989Direct
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.000002279Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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