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Phenotypic Abnormality (PA): Abnormality of the cerebral white matter

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + 8:   Phenotypic abnormality [HP:0000118] <25>
+ + + + + + + 7:   Abnormality of the nervous system [HP:0000707] <4>(142|168) (156|103|45)
+ + + + + + 6:   Abnormality of nervous system morphology [HP:0012639] <5>(69|97) (79|52|16)
+ + + + + 5:   Morphological abnormality of the central nervous system [HP:0002011] <17>(60|85) (69|44|16)
+ + + + 4:   Abnormality of brain morphology [HP:0012443] <13>(43|63) (53|34|15)
+ + + 3:   Abnormality of forebrain morphology [HP:0100547] <6>(26|32) (30|18|5)
+ + 2:   Abnormality of the cerebrum [HP:0002060] <16>(25|31) (29|18|5)
+ 1:   Abnormality of the cerebral subcortex [HP:0010993] <3>(6|9) (6|2|0)
0:   Abnormality of the cerebral white matter [HP:0002500] <15>(6|7) (6|2|0)
- 1:   Abnormal corpus callosum morphology [HP:0001273] <7>(5|7) (5|2|0)
- 1:   Hyperintensity of cerebral white matter on MRI [HP:0030890] <5>(0|0) (0|0|0)
- 1:   Hypointensity of cerebral white matter on MRI [HP:0007103] <5>(0|0) (0|0|0)
- 1:   Abnormality of the periventricular white matter [HP:0002518] <3>(0|0) (0|0|0)
- 1:   Abnormality of the anterior commissure [HP:0030301] <2>(0|0) (0|0|0)
- 1:   Aplasia/Hypoplasia of the cerebral white matter [HP:0012429] <2>(0|0) (0|0|0)
- 1:   Diffuse white matter abnormalities [HP:0007204] <2>(0|0) (0|0|0)
- 1:   Focal white matter lesions [HP:0007042] <2>(0|0) (0|0|0)
- 1:   Multifocal cerebral white matter abnormalities [HP:0007052] <2>(0|0) (0|0|0)
- 1:   Abnormality of the bed nucleus of stria terminalis [HP:0030798] <1>(0|0) (0|0|0)
- 1:   Cerebral white matter atrophy [HP:0012762] <1>(0|0) (0|0|0)
- 1:   Abnormality of the internal capsule [HP:0012502](0|0) (0|0|0)
- 1:   Diffuse swelling of cerebral white matter [HP:0007341](0|0) (0|0|0)
- 1:   Subcortical white matter calcifications [HP:0007346](0|0) (0|0|0)
- 1:   White mater abnormalities in the posterior periventricular region [HP:0006812](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
ADC-like0Direct
Class II aaRS and biotin synthetases0.0001972Direct
Periplasmic binding protein-like II0.003592Inherited
ARID-like0.007295Inherited
Nucleotidylyl transferase0.03578Inherited
Homeodomain-like0.03984Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.000407Direct
Phosphate binding protein-like0.0007268Direct
ARID domain0.004003Inherited
Ypt/Rab-GAP domain of gyp1p0.00467Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.0196Inherited
Homeodomain0.0868Inherited
G proteins0.7078Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
ADC-like0Direct
Class II aaRS and biotin synthetases0.00009441Direct
Periplasmic binding protein-like II0.002109Inherited
ARID-like0.004584Inherited
Nucleotidylyl transferase0.02557Inherited
Homeodomain-like0.02866Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.005229Inherited
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.01106Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)