Phenotypic Abnormality (PA): Abnormal blood glucose concentration

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children)	HP term [HP ID] <#Children>	(#SF|#FA)	#Supra-domain (Single|Duplex|Triple)
+ + + + 4:	Phenotypic abnormality [HP:0000118] <25>
+ + + 3:	Abnormality of metabolism/homeostasis [HP:0001939] <16>	(75|82)	(79|40|16)
+ + 2:	Abnormal homeostasis [HP:0012337] <8>	(44|47)	(44|22|8)
+ 1:	Abnormal glucose homeostasis [HP:0011014] <7>	(11|12)	(12|7|4)
0:	Abnormal blood glucose concentration [HP:0011015] <2>	(7|7)	(7|3|1)
- 1:	Hypoglycemia [HP:0001943] <7>	(7|7)	(7|3|1)
- 1:	Hyperglycemia [HP:0003074] <1>	(0|0)	(0|0|0)

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Superfamily

Superfamily domains annotated to this HP term (Not in SDHP)
Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
Acyl-CoA dehydrogenase C-terminal domain-like	0.0000003136	DIRECT
Acyl-CoA dehydrogenase NM domain-like	0.0000003136	DIRECT
Rudiment single hybrid motif	0.0001921	DIRECT
4Fe-4S ferredoxins	0.0001921	DIRECT
Insulin-like	0.0001921	DIRECT
Thiolase-like	0.0007421	DIRECT
Single hybrid motif	0.0008359	DIRECT

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Family

Family domains annotated to this HP term (Not in SDHP)
Highlighted in gray are those with FDR_all>0.001

SCOP term	FDR (all)	Annotation (direct or inherited)
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain	0.00000001102	DIRECT
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains	0.00000001102	DIRECT
Insulin-like	0.0001114	DIRECT
BC C-terminal domain-like	0.0001114	DIRECT
Biotinyl/lipoyl-carrier proteins and domains	0.0005136	DIRECT
BC N-terminal domain-like	0.001104	INHERITED FROM: Hypoglycemia
BC ATP-binding domain-like	0.001104	INHERITED FROM: Hypoglycemia

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Supra-domain (including individual superfamily)

Supra-domains annotated to this HP term (Not in SPHO)
Highlighted in gray are those with FDR>0.001

Supra-domain (Single)	FDR (all)	Annotation (direct or inherited)
Acyl-CoA dehydrogenase NM domain-like	0.0000001229	DIRECT
Acyl-CoA dehydrogenase C-terminal domain-like	0.0000001229	DIRECT
Insulin-like	0.00009172	DIRECT
Rudiment single hybrid motif	0.00009172	DIRECT
4Fe-4S ferredoxins	0.00009172	DIRECT
Thiolase-like	0.0003852	DIRECT
Single hybrid motif	0.0004373	DIRECT

Supra-domains annotated to this HP term (Not in SPHO)
Highlighted in gray are those with FDR>0.001

Supra-domain (Duplex) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
56645,47203 56645 - Acyl-CoA dehydrogenase NM domain-like 47203 - Acyl-CoA dehydrogenase C-terminal domain-like	0.0000001229	DIRECT
56059,51246 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif	0.00009172	DIRECT
53901,53901 53901 - Thiolase-like 53901 - Thiolase-like	0.0003852	DIRECT

Supra-domains annotated to this HP term (Not in SPHO)
Highlighted in gray are those with FDR>0.001

Supra-domain (Triple) in N- to C-terminal order	FDR (all)	Annotation (direct or inherited)
52440,56059,51246 52440 - PreATP-grasp domain 56059 - Glutathione synthetase ATP-binding domain-like 51246 - Rudiment single hybrid motif	0.00009172	DIRECT