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Phenotypic Abnormality (PA): Abnormality of skin adnexa morphology

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Phenotypic abnormality [HP:0000118] <25>
+ 1:   Abnormality of the integument [HP:0001574] <4>(48|69) (59|37|15)
0:   Abnormality of skin adnexa morphology [HP:0011138] <5>(16|19) (17|6|2)
- 1:   Abnormality of the nail [HP:0001597] <25>(5|5) (5|3|1)
- 1:   Abnormal hair morphology [HP:0001595] <12>(14|18) (15|4|1)
- 1:   Skin appendage neoplasm [HP:0012842] <8>(0|0) (0|0|0)
- 1:   Abnormal sebaceous gland morphology [HP:0032226] <2>(0|0) (0|0|0)
- 1:   Abnormal sweat gland morphology [HP:0000971] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Notch domain0Direct
Plakin repeat0Direct
Smc hinge domain0Direct
CCCH zinc finger0Direct
SET domain0.0181Inherited
BRK domain-like0.02906Inherited
Histone-fold0.03301Inherited
ARID-like0.03301Inherited
Bromodomain0.04158Inherited
HMG-box0.04501Inherited
Intermediate filament protein, coiled coil region0.05138Inherited
BRCT domain0.05558Inherited
GroEL equatorial domain-like0.1823Inherited
MHC antigen-recognition domain0.2347Inherited
EGF/Laminin0.5417Inherited
RING/U-box0.6922Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
CCCH zinc finger0Direct
Notch domain0Direct
Smc hinge domain0Direct
Plakin repeat0Direct
Histone lysine methyltransferases0.0004131Direct
BRK domain-like0.02073Inherited
ARID domain0.02385Inherited
Bromodomain0.02854Inherited
HMG-box0.03104Inherited
Hect, E3 ligase catalytic domain0.03485Inherited
Intermediate filament protein, coiled coil region0.03522Inherited
TBP-associated factors, TAFs0.05753Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.1067Inherited
MHC antigen-recognition domain0.1945Inherited
Laminin-type module0.2679Inherited
Actin/HSP700.2679Inherited
Extended AAA-ATPase domain0.4811Inherited
C1 set domains (antibody constant domain-like)0.5287Inherited
ABC transporter ATPase domain-like0.9477Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Smc hinge domain0Direct
Notch domain0Direct
Plakin repeat0Direct
CCCH zinc finger0Direct
SET domain0.01217Inherited
BRK domain-like0.02032Inherited
Histone-fold0.02338Inherited
ARID-like0.02338Inherited
Bromodomain0.02998Inherited
HMG-box0.03279Inherited
Hect, E3 ligase catalytic domain0.03576Inherited
Intermediate filament protein, coiled coil region0.03797Inherited
BRCT domain0.0414Inherited
GroEL equatorial domain-like0.1509Inherited
MHC antigen-recognition domain0.1991Inherited
EGF/Laminin0.4977Inherited
RING/U-box0.6533Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
75399,75399
  • 75399 - Plakin repeat
  • 75399 - Plakin repeat
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.09436Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.1495Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.1991Inherited
    64593,64593
  • 64593 - Intermediate filament protein, coiled coil region
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.1991Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4258Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)