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Phenotypic Abnormality (PA): Functional abnormality of the inner ear

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Phenotypic abnormality [HP:0000118] <25>
+ + + 3:   Abnormality of the ear [HP:0000598] <2>(17|32) (21|13|11)
+ + 2:   Abnormal ear morphology [HP:0031703] <5>(15|26) (18|11|10)
+ 1:   Abnormality of the inner ear [HP:0000359] <5>(6|9) (8|4|3)
0:   Functional abnormality of the inner ear [HP:0011389] <2>(6|6) (7|4|3)
- 1:   Sensorineural hearing impairment [HP:0000407] <13>(4|3) (5|1|1)
- 1:   Vestibular dysfunction [HP:0001751] <3>(2|3) (2|3|2)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
ADC-like0Direct
Smc hinge domain0Direct
Transcription factor STAT-4 N-domain0.06484Inherited
STAT0.06484Inherited
Integrin domains0.1898Inherited
Family A G protein-coupled receptor-like0.5855Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Smc hinge domain0Direct
Transcription factor STAT-4 N-domain0.05136Inherited
STAT DNA-binding domain0.05136Inherited
STAT0.05136Inherited
Integrin domains0.1632Inherited
Rhodopsin-like0.4354Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Smc hinge domain0Direct
ADC-like0Direct
Transcription factor STAT-4 N-domain0.04904Inherited
STAT0.04904Inherited
Integrin domains0.1579Inherited
Family A G protein-coupled receptor-like0.5426Inherited
Cysteine proteinases0.6943Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
103575,48726
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.04904Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.04904Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.04904Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    101912,103575,48726
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 48726 - Immunoglobulin
  • 0Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.04904Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.04904Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)