SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Phenotypic Abnormality (PA): Fatigable weakness of bulbar muscles

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Abnormality of the nervous system [HP:0000707] <4>(142|168) (156|103|45)
+ + + + + 5:   Phenotypic abnormality [HP:0000118] <25>
+ + + + + 5:   Abnormality of nervous system physiology [HP:0012638] <26>(101|119) (112|81|39)
+ + + + 4:   Abnormal synaptic transmission [HP:0012535] <1>(6|6) (6|2|0)
+ + + + 4:   Abnormality of the musculature [HP:0003011] <3>(64|83) (70|33|9)
+ + + 3:   Abnormal muscle physiology [HP:0011804] <12>(44|59) (51|22|5)
+ + + 3:   Abnormal peripheral nervous system synaptic transmission [HP:0030191] <2>(6|6) (6|2|0)
+ + 2:   Muscle weakness [HP:0001324] <22>(13|14) (15|4|0)
+ + 2:   Abnormal synaptic transmission at the neuromuscular junction [HP:0003398] <4>(6|6) (6|2|0)
+ 1:   Fatigable weakness [HP:0003473] <3>(6|6) (6|2|0)
0:   Fatigable weakness of bulbar muscles [HP:0030192] <3>(2|2) (2|1|0)
- 1:   Fatigable weakness of chewing muscles [HP:0030193](0|0) (0|0|0)
- 1:   Fatigable weakness of speech muscles [HP:0030194](0|0) (0|0|0)
- 1:   Fatigable weakness of swallowing muscles [HP:0030195](2|2) (2|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Calcium-dependent phosphotriesterase0.000001067Direct
RNA-binding domain, RBD0.00001457Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Serum paraoxonase/arylesterase 1, PON10Direct
Canonical RBD0.000005589Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Calcium-dependent phosphotriesterase0.0000004249Direct
RNA-binding domain, RBD0.000006221Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.00004329Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)