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Phenotypic Abnormality (PA): Fatigable weakness of skeletal muscles

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Root: HP Hierarchy (human phenotype with 3 sub-ontologies PA, MI, ON)

Shortest distance to current term (+ for parents, - for children) HP term [HP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Abnormality of the nervous system [HP:0000707] <4>(142|168) (156|103|45)
+ + + + + 5:   Phenotypic abnormality [HP:0000118] <25>
+ + + + + 5:   Abnormality of nervous system physiology [HP:0012638] <26>(101|119) (112|81|39)
+ + + + 4:   Abnormality of the musculature [HP:0003011] <3>(64|83) (70|33|9)
+ + + + 4:   Abnormal synaptic transmission [HP:0012535] <1>(6|6) (6|2|0)
+ + + 3:   Abnormal peripheral nervous system synaptic transmission [HP:0030191] <2>(6|6) (6|2|0)
+ + + 3:   Abnormal muscle physiology [HP:0011804] <12>(44|59) (51|22|5)
+ + 2:   Abnormal synaptic transmission at the neuromuscular junction [HP:0003398] <4>(6|6) (6|2|0)
+ + 2:   Muscle weakness [HP:0001324] <22>(13|14) (15|4|0)
+ 1:   Fatigable weakness [HP:0003473] <3>(6|6) (6|2|0)
0:   Fatigable weakness of skeletal muscles [HP:0030197] <3>(2|2) (2|1|0)
- 1:   Fatigable weakness of distal limb muscles [HP:0030198](0|0) (0|0|0)
- 1:   Fatigable weakness of neck muscles [HP:0030199](2|2) (2|1|0)
- 1:   Fatiguable weakness of proximal limb muscles [HP:0030200](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Neurotransmitter-gated ion-channel transmembrane pore0.00003192Direct
Nicotinic receptor ligand binding domain-like0.00003192Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Neurotransmitter-gated ion-channel transmembrane pore0.00001311Direct
Nicotinic receptor ligand binding domain-like0.00001311Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nicotinic receptor ligand binding domain-like0.00001406Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00001406Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.00001406Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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